Amino acid dipepetide frequency for Aquimarina algiphila

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.511AlaAla: 3.511 ± 0.056	0.503AlaCys: 0.503 ± 0.022	2.922AlaAsp: 2.922 ± 0.04	3.416AlaGlu: 3.416 ± 0.051	2.883AlaPhe: 2.883 ± 0.037	3.713AlaGly: 3.713 ± 0.065	0.981AlaHis: 0.981 ± 0.023	5.335AlaIle: 5.335 ± 0.06	4.3AlaLys: 4.3 ± 0.055	5.514AlaLeu: 5.514 ± 0.057	1.315AlaMet: 1.315 ± 0.031	3.253AlaAsn: 3.253 ± 0.045	1.807AlaPro: 1.807 ± 0.036	2.108AlaGln: 2.108 ± 0.034	1.787AlaArg: 1.787 ± 0.04	3.903AlaSer: 3.903 ± 0.057	3.595AlaThr: 3.595 ± 0.072	3.351AlaVal: 3.351 ± 0.045	0.563AlaTrp: 0.563 ± 0.018	2.299AlaTyr: 2.299 ± 0.037	0.001AlaXaa: 0.001 ± 0.001
Cys	0.388CysAla: 0.388 ± 0.015	0.103CysCys: 0.103 ± 0.008	0.422CysAsp: 0.422 ± 0.016	0.42CysGlu: 0.42 ± 0.014	0.401CysPhe: 0.401 ± 0.016	0.539CysGly: 0.539 ± 0.016	0.165CysHis: 0.165 ± 0.01	0.695CysIle: 0.695 ± 0.023	0.495CysLys: 0.495 ± 0.015	0.608CysLeu: 0.608 ± 0.018	0.148CysMet: 0.148 ± 0.008	0.435CysAsn: 0.435 ± 0.015	0.313CysPro: 0.313 ± 0.02	0.209CysGln: 0.209 ± 0.011	0.209CysArg: 0.209 ± 0.01	0.594CysSer: 0.594 ± 0.02	0.479CysThr: 0.479 ± 0.019	0.404CysVal: 0.404 ± 0.015	0.066CysTrp: 0.066 ± 0.007	0.331CysTyr: 0.331 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.386AspAla: 3.386 ± 0.046	0.456AspCys: 0.456 ± 0.018	3.233AspAsp: 3.233 ± 0.057	3.489AspGlu: 3.489 ± 0.05	3.666AspPhe: 3.666 ± 0.048	3.789AspGly: 3.789 ± 0.077	1.134AspHis: 1.134 ± 0.028	5.053AspIle: 5.053 ± 0.058	4.09AspLys: 4.09 ± 0.048	5.088AspLeu: 5.088 ± 0.059	1.039AspMet: 1.039 ± 0.024	3.49AspAsn: 3.49 ± 0.051	2.029AspPro: 2.029 ± 0.05	2.044AspGln: 2.044 ± 0.033	2.015AspArg: 2.015 ± 0.036	3.22AspSer: 3.22 ± 0.043	3.275AspThr: 3.275 ± 0.054	3.407AspVal: 3.407 ± 0.047	0.827AspTrp: 0.827 ± 0.02	2.64AspTyr: 2.64 ± 0.041	0.001AspXaa: 0.001 ± 0.001
Glu	3.963GluAla: 3.963 ± 0.061	0.344GluCys: 0.344 ± 0.014	3.655GluAsp: 3.655 ± 0.049	5.281GluGlu: 5.281 ± 0.077	2.965GluPhe: 2.965 ± 0.042	3.731GluGly: 3.731 ± 0.047	1.168GluHis: 1.168 ± 0.023	5.863GluIle: 5.863 ± 0.06	5.895GluLys: 5.895 ± 0.081	6.191GluLeu: 6.191 ± 0.073	1.384GluMet: 1.384 ± 0.028	4.513GluAsn: 4.513 ± 0.052	1.474GluPro: 1.474 ± 0.032	2.269GluGln: 2.269 ± 0.035	2.456GluArg: 2.456 ± 0.039	3.431GluSer: 3.431 ± 0.05	3.622GluThr: 3.622 ± 0.044	4.247GluVal: 4.247 ± 0.054	0.657GluTrp: 0.657 ± 0.019	2.781GluTyr: 2.781 ± 0.045	0.0GluXaa: 0.0 ± 0.0
Phe	2.678PheAla: 2.678 ± 0.037	0.415PheCys: 0.415 ± 0.015	3.399PheAsp: 3.399 ± 0.054	3.397PheGlu: 3.397 ± 0.041	2.831PhePhe: 2.831 ± 0.053	3.42PheGly: 3.42 ± 0.05	0.779PheHis: 0.779 ± 0.02	4.037PheIle: 4.037 ± 0.059	3.661PheLys: 3.661 ± 0.046	4.599PheLeu: 4.599 ± 0.058	1.068PheMet: 1.068 ± 0.024	3.331PheAsn: 3.331 ± 0.049	1.664PhePro: 1.664 ± 0.033	1.453PheGln: 1.453 ± 0.028	1.767PheArg: 1.767 ± 0.031	4.129PheSer: 4.129 ± 0.056	3.262PheThr: 3.262 ± 0.048	2.828PheVal: 2.828 ± 0.038	0.579PheTrp: 0.579 ± 0.021	2.227PheTyr: 2.227 ± 0.031	0.001PheXaa: 0.001 ± 0.001
Gly	3.732GlyAla: 3.732 ± 0.055	0.595GlyCys: 0.595 ± 0.022	3.496GlyAsp: 3.496 ± 0.055	3.591GlyGlu: 3.591 ± 0.047	3.617GlyPhe: 3.617 ± 0.05	4.511GlyGly: 4.511 ± 0.078	1.016GlyHis: 1.016 ± 0.024	5.478GlyIle: 5.478 ± 0.054	4.734GlyLys: 4.734 ± 0.056	5.366GlyLeu: 5.366 ± 0.061	1.385GlyMet: 1.385 ± 0.03	4.015GlyAsn: 4.015 ± 0.063	1.275GlyPro: 1.275 ± 0.033	1.795GlyGln: 1.795 ± 0.035	2.114GlyArg: 2.114 ± 0.039	4.113GlySer: 4.113 ± 0.062	4.134GlyThr: 4.134 ± 0.093	4.357GlyVal: 4.357 ± 0.056	0.793GlyTrp: 0.793 ± 0.021	2.958GlyTyr: 2.958 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	0.819HisAla: 0.819 ± 0.019	0.166HisCys: 0.166 ± 0.009	0.826HisAsp: 0.826 ± 0.021	0.952HisGlu: 0.952 ± 0.021	1.098HisPhe: 1.098 ± 0.027	0.96HisGly: 0.96 ± 0.021	0.519HisHis: 0.519 ± 0.016	1.552HisIle: 1.552 ± 0.033	1.359HisLys: 1.359 ± 0.028	1.738HisLeu: 1.738 ± 0.028	0.358HisMet: 0.358 ± 0.015	1.047HisAsn: 1.047 ± 0.024	0.858HisPro: 0.858 ± 0.023	0.775HisGln: 0.775 ± 0.019	0.704HisArg: 0.704 ± 0.018	1.076HisSer: 1.076 ± 0.026	1.039HisThr: 1.039 ± 0.022	0.83HisVal: 0.83 ± 0.022	0.245HisTrp: 0.245 ± 0.012	0.873HisTyr: 0.873 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.406IleAla: 5.406 ± 0.058	0.635IleCys: 0.635 ± 0.019	5.338IleAsp: 5.338 ± 0.056	5.941IleGlu: 5.941 ± 0.058	3.721IlePhe: 3.721 ± 0.047	5.252IleGly: 5.252 ± 0.059	1.589IleHis: 1.589 ± 0.03	6.65IleIle: 6.65 ± 0.082	6.476IleLys: 6.476 ± 0.064	7.406IleLeu: 7.406 ± 0.082	1.396IleMet: 1.396 ± 0.029	5.181IleAsn: 5.181 ± 0.051	3.362IlePro: 3.362 ± 0.043	2.857IleGln: 2.857 ± 0.042	2.856IleArg: 2.856 ± 0.037	6.286IleSer: 6.286 ± 0.063	5.674IleThr: 5.674 ± 0.084	4.861IleVal: 4.861 ± 0.055	0.752IleTrp: 0.752 ± 0.02	3.019IleTyr: 3.019 ± 0.039	0.0IleXaa: 0.0 ± 0.001
Lys	4.453LysAla: 4.453 ± 0.062	0.348LysCys: 0.348 ± 0.014	4.568LysAsp: 4.568 ± 0.054	6.833LysGlu: 6.833 ± 0.092	2.82LysPhe: 2.82 ± 0.039	4.554LysGly: 4.554 ± 0.051	1.423LysHis: 1.423 ± 0.026	6.573LysIle: 6.573 ± 0.072	7.61LysLys: 7.61 ± 0.091	6.439LysLeu: 6.439 ± 0.069	1.846LysMet: 1.846 ± 0.031	5.599LysAsn: 5.599 ± 0.065	2.279LysPro: 2.279 ± 0.039	2.693LysGln: 2.693 ± 0.045	3.061LysArg: 3.061 ± 0.044	4.597LysSer: 4.597 ± 0.055	4.872LysThr: 4.872 ± 0.057	4.548LysVal: 4.548 ± 0.056	0.772LysTrp: 0.772 ± 0.02	3.102LysTyr: 3.102 ± 0.047	0.0LysXaa: 0.0 ± 0.0
Leu	4.989LeuAla: 4.989 ± 0.057	0.698LeuCys: 0.698 ± 0.017	5.13LeuAsp: 5.13 ± 0.051	5.965LeuGlu: 5.965 ± 0.059	4.764LeuPhe: 4.764 ± 0.056	5.564LeuGly: 5.564 ± 0.058	1.55LeuHis: 1.55 ± 0.028	7.19LeuIle: 7.19 ± 0.075	7.58LeuLys: 7.58 ± 0.073	8.365LeuLeu: 8.365 ± 0.094	1.883LeuMet: 1.883 ± 0.032	5.361LeuAsn: 5.361 ± 0.058	3.355LeuPro: 3.355 ± 0.047	3.277LeuGln: 3.277 ± 0.044	3.146LeuArg: 3.146 ± 0.047	6.94LeuSer: 6.94 ± 0.07	5.096LeuThr: 5.096 ± 0.062	4.907LeuVal: 4.907 ± 0.047	0.831LeuTrp: 0.831 ± 0.022	3.23LeuTyr: 3.23 ± 0.041	0.001LeuXaa: 0.001 ± 0.001
Met	1.242MetAla: 1.242 ± 0.027	0.118MetCys: 0.118 ± 0.009	1.073MetAsp: 1.073 ± 0.024	1.127MetGlu: 1.127 ± 0.027	0.82MetPhe: 0.82 ± 0.028	1.246MetGly: 1.246 ± 0.027	0.39MetHis: 0.39 ± 0.014	1.659MetIle: 1.659 ± 0.032	2.095MetLys: 2.095 ± 0.032	1.768MetLeu: 1.768 ± 0.032	0.516MetMet: 0.516 ± 0.015	1.37MetAsn: 1.37 ± 0.027	0.693MetPro: 0.693 ± 0.017	0.724MetGln: 0.724 ± 0.019	0.801MetArg: 0.801 ± 0.021	1.27MetSer: 1.27 ± 0.026	1.107MetThr: 1.107 ± 0.024	1.182MetVal: 1.182 ± 0.027	0.149MetTrp: 0.149 ± 0.009	0.787MetTyr: 0.787 ± 0.022	0.001MetXaa: 0.001 ± 0.001
Asn	3.656AsnAla: 3.656 ± 0.046	0.455AsnCys: 0.455 ± 0.017	3.711AsnAsp: 3.711 ± 0.056	3.774AsnGlu: 3.774 ± 0.043	3.065AsnPhe: 3.065 ± 0.047	4.236AsnGly: 4.236 ± 0.067	1.142AsnHis: 1.142 ± 0.025	5.142AsnIle: 5.142 ± 0.055	4.518AsnLys: 4.518 ± 0.058	5.307AsnLeu: 5.307 ± 0.052	1.222AsnMet: 1.222 ± 0.027	4.124AsnAsn: 4.124 ± 0.068	2.774AsnPro: 2.774 ± 0.039	2.379AsnGln: 2.379 ± 0.036	2.358AsnArg: 2.358 ± 0.035	3.93AsnSer: 3.93 ± 0.054	4.451AsnThr: 4.451 ± 0.064	3.459AsnVal: 3.459 ± 0.053	0.807AsnTrp: 0.807 ± 0.024	2.812AsnTyr: 2.812 ± 0.039	0.001AsnXaa: 0.001 ± 0.001
Pro	1.702ProAla: 1.702 ± 0.034	0.188ProCys: 0.188 ± 0.009	2.224ProAsp: 2.224 ± 0.042	2.759ProGlu: 2.759 ± 0.039	1.86ProPhe: 1.86 ± 0.035	2.037ProGly: 2.037 ± 0.048	0.559ProHis: 0.559 ± 0.018	2.849ProIle: 2.849 ± 0.048	2.615ProLys: 2.615 ± 0.04	2.788ProLeu: 2.788 ± 0.042	0.614ProMet: 0.614 ± 0.016	2.279ProAsn: 2.279 ± 0.038	0.931ProPro: 0.931 ± 0.028	1.059ProGln: 1.059 ± 0.024	0.943ProArg: 0.943 ± 0.023	2.298ProSer: 2.298 ± 0.04	1.936ProThr: 1.936 ± 0.042	2.201ProVal: 2.201 ± 0.039	0.334ProTrp: 0.334 ± 0.013	1.34ProTyr: 1.34 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	1.793GlnAla: 1.793 ± 0.03	0.202GlnCys: 0.202 ± 0.012	1.761GlnAsp: 1.761 ± 0.034	2.519GlnGlu: 2.519 ± 0.042	1.652GlnPhe: 1.652 ± 0.025	1.903GlnGly: 1.903 ± 0.033	0.637GlnHis: 0.637 ± 0.019	2.737GlnIle: 2.737 ± 0.04	3.102GlnLys: 3.102 ± 0.04	3.338GlnLeu: 3.338 ± 0.05	0.739GlnMet: 0.739 ± 0.021	2.375GlnAsn: 2.375 ± 0.035	1.076GlnPro: 1.076 ± 0.029	1.474GlnGln: 1.474 ± 0.033	1.267GlnArg: 1.267 ± 0.023	2.01GlnSer: 2.01 ± 0.032	1.883GlnThr: 1.883 ± 0.032	1.845GlnVal: 1.845 ± 0.031	0.402GlnTrp: 0.402 ± 0.014	1.513GlnTyr: 1.513 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	1.942ArgAla: 1.942 ± 0.035	0.221ArgCys: 0.221 ± 0.011	1.888ArgAsp: 1.888 ± 0.03	2.18ArgGlu: 2.18 ± 0.036	1.972ArgPhe: 1.972 ± 0.029	1.913ArgGly: 1.913 ± 0.034	0.568ArgHis: 0.568 ± 0.019	3.19ArgIle: 3.19 ± 0.042	2.938ArgLys: 2.938 ± 0.049	3.339ArgLeu: 3.339 ± 0.051	0.869ArgMet: 0.869 ± 0.021	2.215ArgAsn: 2.215 ± 0.036	1.084ArgPro: 1.084 ± 0.027	1.119ArgGln: 1.119 ± 0.023	1.402ArgArg: 1.402 ± 0.03	2.092ArgSer: 2.092 ± 0.036	1.955ArgThr: 1.955 ± 0.035	2.072ArgVal: 2.072 ± 0.03	0.421ArgTrp: 0.421 ± 0.013	1.698ArgTyr: 1.698 ± 0.033	0.001ArgXaa: 0.001 ± 0.001
Ser	3.474SerAla: 3.474 ± 0.044	0.701SerCys: 0.701 ± 0.022	3.692SerAsp: 3.692 ± 0.045	4.092SerGlu: 4.092 ± 0.051	3.945SerPhe: 3.945 ± 0.058	4.81SerGly: 4.81 ± 0.069	1.071SerHis: 1.071 ± 0.025	5.938SerIle: 5.938 ± 0.057	5.122SerLys: 5.122 ± 0.054	5.943SerLeu: 5.943 ± 0.068	1.214SerMet: 1.214 ± 0.025	4.186SerAsn: 4.186 ± 0.054	2.166SerPro: 2.166 ± 0.037	2.163SerGln: 2.163 ± 0.038	2.252SerArg: 2.252 ± 0.037	4.746SerSer: 4.746 ± 0.069	3.808SerThr: 3.808 ± 0.053	3.822SerVal: 3.822 ± 0.04	0.788SerTrp: 0.788 ± 0.025	2.971SerTyr: 2.971 ± 0.041	0.001SerXaa: 0.001 ± 0.001
Thr	3.607ThrAla: 3.607 ± 0.066	0.365ThrCys: 0.365 ± 0.015	3.357ThrAsp: 3.357 ± 0.056	3.479ThrGlu: 3.479 ± 0.044	3.129ThrPhe: 3.129 ± 0.046	4.254ThrGly: 4.254 ± 0.078	1.037ThrHis: 1.037 ± 0.023	5.906ThrIle: 5.906 ± 0.075	4.184ThrLys: 4.184 ± 0.052	5.6ThrLeu: 5.6 ± 0.058	0.994ThrMet: 0.994 ± 0.027	3.63ThrAsn: 3.63 ± 0.055	2.683ThrPro: 2.683 ± 0.054	1.988ThrGln: 1.988 ± 0.034	1.795ThrArg: 1.795 ± 0.033	4.325ThrSer: 4.325 ± 0.054	4.209ThrThr: 4.209 ± 0.073	3.72ThrVal: 3.72 ± 0.073	0.623ThrTrp: 0.623 ± 0.021	2.721ThrTyr: 2.721 ± 0.052	0.002ThrXaa: 0.002 ± 0.001
Val	3.504ValAla: 3.504 ± 0.046	0.459ValCys: 0.459 ± 0.016	3.453ValAsp: 3.453 ± 0.047	3.521ValGlu: 3.521 ± 0.05	3.352ValPhe: 3.352 ± 0.04	3.411ValGly: 3.411 ± 0.051	0.947ValHis: 0.947 ± 0.026	4.917ValIle: 4.917 ± 0.049	4.112ValLys: 4.112 ± 0.052	5.631ValLeu: 5.631 ± 0.053	1.163ValMet: 1.163 ± 0.024	3.483ValAsn: 3.483 ± 0.044	1.949ValPro: 1.949 ± 0.035	1.773ValGln: 1.773 ± 0.031	1.95ValArg: 1.95 ± 0.032	4.477ValSer: 4.477 ± 0.062	3.82ValThr: 3.82 ± 0.083	3.707ValVal: 3.707 ± 0.053	0.605ValTrp: 0.605 ± 0.017	2.31ValTyr: 2.31 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	0.527TrpAla: 0.527 ± 0.019	0.103TrpCys: 0.103 ± 0.008	0.659TrpAsp: 0.659 ± 0.022	0.704TrpGlu: 0.704 ± 0.021	0.557TrpPhe: 0.557 ± 0.016	0.712TrpGly: 0.712 ± 0.018	0.231TrpHis: 0.231 ± 0.01	0.844TrpIle: 0.844 ± 0.021	0.851TrpLys: 0.851 ± 0.024	0.992TrpLeu: 0.992 ± 0.026	0.293TrpMet: 0.293 ± 0.01	0.75TrpAsn: 0.75 ± 0.022	0.253TrpPro: 0.253 ± 0.011	0.407TrpGln: 0.407 ± 0.016	0.415TrpArg: 0.415 ± 0.012	0.711TrpSer: 0.711 ± 0.024	0.582TrpThr: 0.582 ± 0.019	0.643TrpVal: 0.643 ± 0.019	0.173TrpTrp: 0.173 ± 0.011	0.481TrpTyr: 0.481 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.288TyrAla: 2.288 ± 0.038	0.347TyrCys: 0.347 ± 0.012	2.561TyrAsp: 2.561 ± 0.041	2.453TyrGlu: 2.453 ± 0.041	2.409TyrPhe: 2.409 ± 0.041	2.521TyrGly: 2.521 ± 0.034	0.889TyrHis: 0.889 ± 0.024	3.047TyrIle: 3.047 ± 0.041	3.254TyrLys: 3.254 ± 0.046	3.8TyrLeu: 3.8 ± 0.049	0.693TyrMet: 0.693 ± 0.018	2.686TyrAsn: 2.686 ± 0.044	1.488TyrPro: 1.488 ± 0.029	1.662TyrGln: 1.662 ± 0.032	1.781TyrArg: 1.781 ± 0.035	2.756TyrSer: 2.756 ± 0.044	2.807TyrThr: 2.807 ± 0.045	2.154TyrVal: 2.154 ± 0.037	0.5TyrTrp: 0.5 ± 0.013	2.047TyrTyr: 2.047 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.003XaaIle: 0.003 ± 0.001	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.001	0.0XaaArg: 0.0 ± 0.0	0.002XaaSer: 0.002 ± 0.001	0.002XaaThr: 0.002 ± 0.001	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.001	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6064 proteins (2018512 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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