Amino acid dipepetide frequency for Sutterella wadsworthensis 2_1_59BFAA

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.802AlaAla: 14.802 ± 0.219	1.628AlaCys: 1.628 ± 0.053	6.465AlaAsp: 6.465 ± 0.107	7.395AlaGlu: 7.395 ± 0.135	4.321AlaPhe: 4.321 ± 0.088	9.707AlaGly: 9.707 ± 0.14	1.925AlaHis: 1.925 ± 0.048	4.648AlaIle: 4.648 ± 0.099	4.588AlaLys: 4.588 ± 0.095	11.319AlaLeu: 11.319 ± 0.144	3.239AlaMet: 3.239 ± 0.072	2.67AlaAsn: 2.67 ± 0.064	4.453AlaPro: 4.453 ± 0.106	3.386AlaGln: 3.386 ± 0.083	7.396AlaArg: 7.396 ± 0.14	6.036AlaSer: 6.036 ± 0.094	4.781AlaThr: 4.781 ± 0.086	9.506AlaVal: 9.506 ± 0.128	1.477AlaTrp: 1.477 ± 0.051	2.363AlaTyr: 2.363 ± 0.061	0.0AlaXaa: 0.0 ± 0.0
Cys	1.497CysAla: 1.497 ± 0.056	0.244CysCys: 0.244 ± 0.022	0.671CysAsp: 0.671 ± 0.033	0.776CysGlu: 0.776 ± 0.04	0.498CysPhe: 0.498 ± 0.027	1.397CysGly: 1.397 ± 0.06	0.338CysHis: 0.338 ± 0.027	0.567CysIle: 0.567 ± 0.031	0.357CysLys: 0.357 ± 0.022	1.121CysLeu: 1.121 ± 0.042	0.293CysMet: 0.293 ± 0.02	0.336CysAsn: 0.336 ± 0.028	0.801CysPro: 0.801 ± 0.038	0.304CysGln: 0.304 ± 0.021	1.108CysArg: 1.108 ± 0.05	0.697CysSer: 0.697 ± 0.032	0.721CysThr: 0.721 ± 0.035	0.995CysVal: 0.995 ± 0.042	0.19CysTrp: 0.19 ± 0.017	0.287CysTyr: 0.287 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	6.309AspAla: 6.309 ± 0.098	0.679AspCys: 0.679 ± 0.031	3.162AspAsp: 3.162 ± 0.08	4.186AspGlu: 4.186 ± 0.089	2.487AspPhe: 2.487 ± 0.058	4.428AspGly: 4.428 ± 0.091	0.889AspHis: 0.889 ± 0.035	2.732AspIle: 2.732 ± 0.067	2.187AspLys: 2.187 ± 0.056	4.971AspLeu: 4.971 ± 0.086	1.576AspMet: 1.576 ± 0.05	1.497AspAsn: 1.497 ± 0.05	2.994AspPro: 2.994 ± 0.061	1.232AspGln: 1.232 ± 0.039	3.54AspArg: 3.54 ± 0.073	2.308AspSer: 2.308 ± 0.063	2.525AspThr: 2.525 ± 0.066	4.577AspVal: 4.577 ± 0.096	0.911AspTrp: 0.911 ± 0.036	1.439AspTyr: 1.439 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	8.385GluAla: 8.385 ± 0.158	0.679GluCys: 0.679 ± 0.032	3.251GluAsp: 3.251 ± 0.08	4.584GluGlu: 4.584 ± 0.106	2.024GluPhe: 2.024 ± 0.055	5.148GluGly: 5.148 ± 0.103	1.382GluHis: 1.382 ± 0.048	3.299GluIle: 3.299 ± 0.075	3.764GluLys: 3.764 ± 0.085	6.184GluLeu: 6.184 ± 0.101	1.62GluMet: 1.62 ± 0.047	2.114GluAsn: 2.114 ± 0.051	2.5GluPro: 2.5 ± 0.063	1.92GluGln: 1.92 ± 0.049	4.969GluArg: 4.969 ± 0.107	3.254GluSer: 3.254 ± 0.067	3.623GluThr: 3.623 ± 0.069	4.546GluVal: 4.546 ± 0.084	0.788GluTrp: 0.788 ± 0.034	1.376GluTyr: 1.376 ± 0.046	0.0GluXaa: 0.0 ± 0.0
Phe	4.003PheAla: 4.003 ± 0.081	0.587PheCys: 0.587 ± 0.029	2.584PheAsp: 2.584 ± 0.061	2.432PheGlu: 2.432 ± 0.061	1.696PhePhe: 1.696 ± 0.055	3.613PheGly: 3.613 ± 0.081	0.664PheHis: 0.664 ± 0.032	2.032PheIle: 2.032 ± 0.055	1.447PheLys: 1.447 ± 0.048	3.352PheLeu: 3.352 ± 0.078	1.102PheMet: 1.102 ± 0.041	1.35PheAsn: 1.35 ± 0.049	1.413PhePro: 1.413 ± 0.046	0.88PheGln: 0.88 ± 0.031	2.211PheArg: 2.211 ± 0.066	2.381PheSer: 2.381 ± 0.062	2.275PheThr: 2.275 ± 0.057	3.075PheVal: 3.075 ± 0.064	0.533PheTrp: 0.533 ± 0.029	0.971PheTyr: 0.971 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	7.91GlyAla: 7.91 ± 0.141	1.322GlyCys: 1.322 ± 0.047	3.961GlyAsp: 3.961 ± 0.092	4.915GlyGlu: 4.915 ± 0.092	3.533GlyPhe: 3.533 ± 0.071	5.965GlyGly: 5.965 ± 0.13	1.62GlyHis: 1.62 ± 0.055	4.735GlyIle: 4.735 ± 0.078	3.383GlyLys: 3.383 ± 0.078	8.321GlyLeu: 8.321 ± 0.115	2.431GlyMet: 2.431 ± 0.058	2.22GlyAsn: 2.22 ± 0.064	2.342GlyPro: 2.342 ± 0.055	1.909GlyGln: 1.909 ± 0.054	6.16GlyArg: 6.16 ± 0.111	4.405GlySer: 4.405 ± 0.087	4.666GlyThr: 4.666 ± 0.093	6.557GlyVal: 6.557 ± 0.101	1.266GlyTrp: 1.266 ± 0.047	2.144GlyTyr: 2.144 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	2.077HisAla: 2.077 ± 0.054	0.353HisCys: 0.353 ± 0.024	1.134HisAsp: 1.134 ± 0.043	1.253HisGlu: 1.253 ± 0.043	0.841HisPhe: 0.841 ± 0.031	1.596HisGly: 1.596 ± 0.055	0.514HisHis: 0.514 ± 0.043	0.907HisIle: 0.907 ± 0.035	0.723HisLys: 0.723 ± 0.034	1.779HisLeu: 1.779 ± 0.046	0.48HisMet: 0.48 ± 0.028	0.496HisAsn: 0.496 ± 0.025	1.212HisPro: 1.212 ± 0.041	0.598HisGln: 0.598 ± 0.026	1.197HisArg: 1.197 ± 0.045	0.949HisSer: 0.949 ± 0.031	0.892HisThr: 0.892 ± 0.038	1.478HisVal: 1.478 ± 0.049	0.297HisTrp: 0.297 ± 0.02	0.549HisTyr: 0.549 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.899IleAla: 5.899 ± 0.09	0.659IleCys: 0.659 ± 0.028	3.162IleAsp: 3.162 ± 0.07	3.689IleGlu: 3.689 ± 0.073	1.688IlePhe: 1.688 ± 0.053	4.095IleGly: 4.095 ± 0.089	0.941IleHis: 0.941 ± 0.037	2.358IleIle: 2.358 ± 0.06	1.848IleLys: 1.848 ± 0.056	4.489IleLeu: 4.489 ± 0.082	1.119IleMet: 1.119 ± 0.04	1.589IleAsn: 1.589 ± 0.054	2.527IlePro: 2.527 ± 0.055	1.295IleGln: 1.295 ± 0.048	3.521IleArg: 3.521 ± 0.068	2.873IleSer: 2.873 ± 0.064	2.656IleThr: 2.656 ± 0.066	3.998IleVal: 3.998 ± 0.073	0.485IleTrp: 0.485 ± 0.026	1.14IleTyr: 1.14 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	5.607LysAla: 5.607 ± 0.111	0.48LysCys: 0.48 ± 0.03	2.419LysAsp: 2.419 ± 0.064	2.476LysGlu: 2.476 ± 0.064	1.242LysPhe: 1.242 ± 0.047	3.363LysGly: 3.363 ± 0.077	0.911LysHis: 0.911 ± 0.036	2.107LysIle: 2.107 ± 0.056	2.45LysLys: 2.45 ± 0.079	4.203LysLeu: 4.203 ± 0.08	1.235LysMet: 1.235 ± 0.045	1.599LysAsn: 1.599 ± 0.052	2.195LysPro: 2.195 ± 0.059	1.189LysGln: 1.189 ± 0.044	2.755LysArg: 2.755 ± 0.07	2.584LysSer: 2.584 ± 0.066	3.025LysThr: 3.025 ± 0.081	3.101LysVal: 3.101 ± 0.072	0.468LysTrp: 0.468 ± 0.026	0.937LysTyr: 0.937 ± 0.04	0.0LysXaa: 0.0 ± 0.0
Leu	10.965LeuAla: 10.965 ± 0.147	1.275LeuCys: 1.275 ± 0.043	5.246LeuAsp: 5.246 ± 0.09	6.393LeuGlu: 6.393 ± 0.101	3.596LeuPhe: 3.596 ± 0.09	7.35LeuGly: 7.35 ± 0.114	1.704LeuHis: 1.704 ± 0.055	4.374LeuIle: 4.374 ± 0.079	4.502LeuLys: 4.502 ± 0.086	8.68LeuLeu: 8.68 ± 0.161	2.816LeuMet: 2.816 ± 0.075	2.952LeuAsn: 2.952 ± 0.063	5.063LeuPro: 5.063 ± 0.102	2.663LeuGln: 2.663 ± 0.064	6.434LeuArg: 6.434 ± 0.101	6.526LeuSer: 6.526 ± 0.098	5.777LeuThr: 5.777 ± 0.103	7.01LeuVal: 7.01 ± 0.107	1.094LeuTrp: 1.094 ± 0.047	2.188LeuTyr: 2.188 ± 0.063	0.0LeuXaa: 0.0 ± 0.0
Met	2.893MetAla: 2.893 ± 0.072	0.243MetCys: 0.243 ± 0.018	1.212MetAsp: 1.212 ± 0.039	1.234MetGlu: 1.234 ± 0.045	0.704MetPhe: 0.704 ± 0.035	2.023MetGly: 2.023 ± 0.057	0.567MetHis: 0.567 ± 0.026	1.42MetIle: 1.42 ± 0.048	1.757MetLys: 1.757 ± 0.051	2.847MetLeu: 2.847 ± 0.066	0.866MetMet: 0.866 ± 0.031	1.003MetAsn: 1.003 ± 0.037	1.601MetPro: 1.601 ± 0.047	1.003MetGln: 1.003 ± 0.036	1.853MetArg: 1.853 ± 0.058	1.868MetSer: 1.868 ± 0.054	2.446MetThr: 2.446 ± 0.055	1.622MetVal: 1.622 ± 0.055	0.194MetTrp: 0.194 ± 0.015	0.428MetTyr: 0.428 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.365AsnAla: 3.365 ± 0.074	0.353AsnCys: 0.353 ± 0.022	1.517AsnAsp: 1.517 ± 0.051	1.89AsnGlu: 1.89 ± 0.052	1.182AsnPhe: 1.182 ± 0.038	2.64AsnGly: 2.64 ± 0.072	0.587AsnHis: 0.587 ± 0.029	1.513AsnIle: 1.513 ± 0.053	1.155AsnLys: 1.155 ± 0.049	2.729AsnLeu: 2.729 ± 0.057	0.79AsnMet: 0.79 ± 0.034	0.955AsnAsn: 0.955 ± 0.045	1.996AsnPro: 1.996 ± 0.06	0.807AsnGln: 0.807 ± 0.033	1.906AsnArg: 1.906 ± 0.046	1.464AsnSer: 1.464 ± 0.043	1.544AsnThr: 1.544 ± 0.056	2.317AsnVal: 2.317 ± 0.065	0.405AsnTrp: 0.405 ± 0.026	0.781AsnTyr: 0.781 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	5.344ProAla: 5.344 ± 0.114	0.556ProCys: 0.556 ± 0.028	3.047ProAsp: 3.047 ± 0.071	4.26ProGlu: 4.26 ± 0.084	1.816ProPhe: 1.816 ± 0.047	3.537ProGly: 3.537 ± 0.084	0.889ProHis: 0.889 ± 0.038	1.878ProIle: 1.878 ± 0.051	2.154ProLys: 2.154 ± 0.058	3.981ProLeu: 3.981 ± 0.082	1.237ProMet: 1.237 ± 0.041	1.295ProAsn: 1.295 ± 0.04	1.455ProPro: 1.455 ± 0.062	1.345ProGln: 1.345 ± 0.045	2.249ProArg: 2.249 ± 0.071	2.476ProSer: 2.476 ± 0.064	2.083ProThr: 2.083 ± 0.05	4.434ProVal: 4.434 ± 0.083	0.606ProTrp: 0.606 ± 0.031	1.169ProTyr: 1.169 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.253GlnAla: 3.253 ± 0.078	0.339GlnCys: 0.339 ± 0.021	1.302GlnAsp: 1.302 ± 0.043	1.637GlnGlu: 1.637 ± 0.055	1.064GlnPhe: 1.064 ± 0.037	2.108GlnGly: 2.108 ± 0.054	0.511GlnHis: 0.511 ± 0.026	1.654GlnIle: 1.654 ± 0.046	1.532GlnLys: 1.532 ± 0.046	2.508GlnLeu: 2.508 ± 0.056	0.847GlnMet: 0.847 ± 0.032	0.948GlnAsn: 0.948 ± 0.041	1.241GlnPro: 1.241 ± 0.043	1.055GlnGln: 1.055 ± 0.046	1.704GlnArg: 1.704 ± 0.05	1.494GlnSer: 1.494 ± 0.049	1.772GlnThr: 1.772 ± 0.047	1.855GlnVal: 1.855 ± 0.05	0.363GlnTrp: 0.363 ± 0.019	0.762GlnTyr: 0.762 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	6.68ArgAla: 6.68 ± 0.11	0.721ArgCys: 0.721 ± 0.037	3.405ArgAsp: 3.405 ± 0.076	4.687ArgGlu: 4.687 ± 0.095	2.746ArgPhe: 2.746 ± 0.07	4.278ArgGly: 4.278 ± 0.081	1.58ArgHis: 1.58 ± 0.045	4.14ArgIle: 4.14 ± 0.084	2.788ArgLys: 2.788 ± 0.075	7.163ArgLeu: 7.163 ± 0.126	2.106ArgMet: 2.106 ± 0.057	2.049ArgAsn: 2.049 ± 0.061	3.093ArgPro: 3.093 ± 0.082	2.176ArgGln: 2.176 ± 0.061	5.838ArgArg: 5.838 ± 0.127	3.615ArgSer: 3.615 ± 0.086	4.066ArgThr: 4.066 ± 0.079	4.643ArgVal: 4.643 ± 0.08	1.011ArgTrp: 1.011 ± 0.04	1.699ArgTyr: 1.699 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	6.036SerAla: 6.036 ± 0.111	0.712SerCys: 0.712 ± 0.035	2.934SerAsp: 2.934 ± 0.068	3.302SerGlu: 3.302 ± 0.081	2.362SerPhe: 2.362 ± 0.062	5.137SerGly: 5.137 ± 0.096	1.071SerHis: 1.071 ± 0.04	2.815SerIle: 2.815 ± 0.06	2.179SerLys: 2.179 ± 0.059	5.589SerLeu: 5.589 ± 0.114	1.527SerMet: 1.527 ± 0.047	1.548SerAsn: 1.548 ± 0.047	2.492SerPro: 2.492 ± 0.064	1.493SerGln: 1.493 ± 0.051	3.836SerArg: 3.836 ± 0.087	3.257SerSer: 3.257 ± 0.077	3.007SerThr: 3.007 ± 0.072	4.478SerVal: 4.478 ± 0.079	0.729SerTrp: 0.729 ± 0.032	1.336SerTyr: 1.336 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	6.08ThrAla: 6.08 ± 0.102	0.654ThrCys: 0.654 ± 0.035	2.998ThrAsp: 2.998 ± 0.065	3.015ThrGlu: 3.015 ± 0.07	2.141ThrPhe: 2.141 ± 0.056	5.331ThrGly: 5.331 ± 0.094	1.077ThrHis: 1.077 ± 0.039	2.994ThrIle: 2.994 ± 0.072	2.218ThrLys: 2.218 ± 0.06	5.887ThrLeu: 5.887 ± 0.101	1.272ThrMet: 1.272 ± 0.042	1.604ThrAsn: 1.604 ± 0.046	3.218ThrPro: 3.218 ± 0.072	1.539ThrGln: 1.539 ± 0.052	3.185ThrArg: 3.185 ± 0.069	2.911ThrSer: 2.911 ± 0.066	3.148ThrThr: 3.148 ± 0.087	4.832ThrVal: 4.832 ± 0.089	0.614ThrTrp: 0.614 ± 0.031	1.234ThrTyr: 1.234 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	7.422ValAla: 7.422 ± 0.107	1.151ValCys: 1.151 ± 0.05	4.137ValAsp: 4.137 ± 0.081	5.099ValGlu: 5.099 ± 0.088	3.116ValPhe: 3.116 ± 0.08	5.01ValGly: 5.01 ± 0.101	1.46ValHis: 1.46 ± 0.047	4.173ValIle: 4.173 ± 0.078	3.853ValLys: 3.853 ± 0.074	7.689ValLeu: 7.689 ± 0.12	2.237ValMet: 2.237 ± 0.063	2.485ValAsn: 2.485 ± 0.072	3.662ValPro: 3.662 ± 0.07	2.016ValGln: 2.016 ± 0.056	5.772ValArg: 5.772 ± 0.106	4.775ValSer: 4.775 ± 0.081	4.949ValThr: 4.949 ± 0.085	6.172ValVal: 6.172 ± 0.1	0.993ValTrp: 0.993 ± 0.041	1.699ValTyr: 1.699 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	1.165TrpAla: 1.165 ± 0.043	0.225TrpCys: 0.225 ± 0.019	0.598TrpAsp: 0.598 ± 0.029	0.675TrpGlu: 0.675 ± 0.03	0.529TrpPhe: 0.529 ± 0.028	0.866TrpGly: 0.866 ± 0.042	0.271TrpHis: 0.271 ± 0.02	0.754TrpIle: 0.754 ± 0.032	0.59TrpLys: 0.59 ± 0.031	1.584TrpLeu: 1.584 ± 0.05	0.434TrpMet: 0.434 ± 0.023	0.447TrpAsn: 0.447 ± 0.027	0.5TrpPro: 0.5 ± 0.028	0.481TrpGln: 0.481 ± 0.024	1.067TrpArg: 1.067 ± 0.044	0.647TrpSer: 0.647 ± 0.029	0.79TrpThr: 0.79 ± 0.034	0.877TrpVal: 0.877 ± 0.04	0.186TrpTrp: 0.186 ± 0.015	0.313TrpTyr: 0.313 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.413TyrAla: 2.413 ± 0.056	0.338TyrCys: 0.338 ± 0.022	1.425TyrAsp: 1.425 ± 0.042	1.513TyrGlu: 1.513 ± 0.044	1.018TyrPhe: 1.018 ± 0.039	2.171TyrGly: 2.171 ± 0.055	0.422TyrHis: 0.422 ± 0.024	0.934TyrIle: 0.934 ± 0.032	0.87TyrLys: 0.87 ± 0.037	2.21TyrLeu: 2.21 ± 0.052	0.557TyrMet: 0.557 ± 0.026	0.742TyrAsn: 0.742 ± 0.037	1.052TyrPro: 1.052 ± 0.039	0.659TyrGln: 0.659 ± 0.034	1.779TyrArg: 1.779 ± 0.054	1.319TyrSer: 1.319 ± 0.047	1.204TyrThr: 1.204 ± 0.044	1.798TyrVal: 1.798 ± 0.052	0.39TyrTrp: 0.39 ± 0.024	0.571TyrTyr: 0.571 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2327 proteins (737528 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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