Amino acid dipepetide frequency for Garlic virus E

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.961AlaAla: 4.961 ± 0.523
2.481AlaCys: 2.481 ± 0.462
4.651AlaAsp: 4.651 ± 1.078
3.101AlaGlu: 3.101 ± 0.419
3.411AlaPhe: 3.411 ± 0.975
4.651AlaGly: 4.651 ± 0.748
2.171AlaHis: 2.171 ± 0.789
2.791AlaIle: 2.791 ± 1.286
7.442AlaLys: 7.442 ± 1.4
8.372AlaLeu: 8.372 ± 1.876
1.86AlaMet: 1.86 ± 0.898
3.101AlaAsn: 3.101 ± 0.879
3.101AlaPro: 3.101 ± 0.768
4.031AlaGln: 4.031 ± 0.739
3.721AlaArg: 3.721 ± 0.484
4.031AlaSer: 4.031 ± 1.06
5.891AlaThr: 5.891 ± 0.843
4.341AlaVal: 4.341 ± 1.218
0.93AlaTrp: 0.93 ± 0.767
3.101AlaTyr: 3.101 ± 1.925
0.0AlaXaa: 0.0 ± 0.0
Cys
0.62CysAla: 0.62 ± 0.385
0.62CysCys: 0.62 ± 0.646
0.93CysAsp: 0.93 ± 0.454
1.24CysGlu: 1.24 ± 0.77
0.62CysPhe: 0.62 ± 0.477
2.791CysGly: 2.791 ± 1.37
0.31CysHis: 0.31 ± 0.193
0.0CysIle: 0.0 ± 0.0
1.55CysLys: 1.55 ± 0.969
1.86CysLeu: 1.86 ± 0.725
0.31CysMet: 0.31 ± 0.337
0.31CysAsn: 0.31 ± 0.193
1.24CysPro: 1.24 ± 0.407
0.62CysGln: 0.62 ± 0.305
0.93CysArg: 0.93 ± 0.655
1.24CysSer: 1.24 ± 0.57
1.55CysThr: 1.55 ± 1.023
0.62CysVal: 0.62 ± 0.617
0.0CysTrp: 0.0 ± 0.0
2.481CysTyr: 2.481 ± 1.254
0.0CysXaa: 0.0 ± 0.0
Asp
5.271AspAla: 5.271 ± 0.713
2.171AspCys: 2.171 ± 0.737
4.341AspAsp: 4.341 ± 0.834
4.031AspGlu: 4.031 ± 0.955
4.341AspPhe: 4.341 ± 0.929
1.86AspGly: 1.86 ± 0.729
1.86AspHis: 1.86 ± 0.743
3.721AspIle: 3.721 ± 1.346
2.171AspLys: 2.171 ± 1.023
8.062AspLeu: 8.062 ± 1.473
1.86AspMet: 1.86 ± 0.54
2.481AspAsn: 2.481 ± 0.724
3.411AspPro: 3.411 ± 0.724
2.481AspGln: 2.481 ± 0.685
1.55AspArg: 1.55 ± 0.648
4.031AspSer: 4.031 ± 0.953
2.171AspThr: 2.171 ± 1.348
3.101AspVal: 3.101 ± 0.419
0.62AspTrp: 0.62 ± 0.385
2.481AspTyr: 2.481 ± 1.289
0.0AspXaa: 0.0 ± 0.0
Glu
4.341GluAla: 4.341 ± 1.198
0.93GluCys: 0.93 ± 0.511
3.411GluAsp: 3.411 ± 1.208
3.101GluGlu: 3.101 ± 1.665
1.86GluPhe: 1.86 ± 0.513
2.481GluGly: 2.481 ± 1.025
1.24GluHis: 1.24 ± 0.502
2.791GluIle: 2.791 ± 1.272
2.171GluLys: 2.171 ± 1.348
4.961GluLeu: 4.961 ± 0.694
0.31GluMet: 0.31 ± 0.193
2.791GluAsn: 2.791 ± 0.608
3.411GluPro: 3.411 ± 0.724
3.721GluGln: 3.721 ± 1.88
3.411GluArg: 3.411 ± 1.453
4.341GluSer: 4.341 ± 1.395
2.791GluThr: 2.791 ± 1.14
2.481GluVal: 2.481 ± 0.961
0.31GluTrp: 0.31 ± 0.353
0.93GluTyr: 0.93 ± 0.429
0.0GluXaa: 0.0 ± 0.0
Phe
3.411PheAla: 3.411 ± 0.576
1.24PheCys: 1.24 ± 0.627
4.031PheAsp: 4.031 ± 0.377
3.101PheGlu: 3.101 ± 0.524
2.171PhePhe: 2.171 ± 1.092
2.171PheGly: 2.171 ± 0.475
0.93PheHis: 0.93 ± 0.368
1.24PheIle: 1.24 ± 0.502
2.791PheLys: 2.791 ± 0.585
1.55PheLeu: 1.55 ± 0.721
1.86PheMet: 1.86 ± 0.436
2.481PheAsn: 2.481 ± 0.776
2.171PhePro: 2.171 ± 1.104
1.55PheGln: 1.55 ± 0.744
0.93PheArg: 0.93 ± 0.576
4.031PheSer: 4.031 ± 1.277
0.93PheThr: 0.93 ± 0.429
2.481PheVal: 2.481 ± 0.554
0.0PheTrp: 0.0 ± 0.0
2.171PheTyr: 2.171 ± 0.846
0.0PheXaa: 0.0 ± 0.0
Gly
4.341GlyAla: 4.341 ± 0.398
0.62GlyCys: 0.62 ± 0.385
3.411GlyAsp: 3.411 ± 0.9
2.171GlyGlu: 2.171 ± 1.104
1.55GlyPhe: 1.55 ± 0.687
3.721GlyGly: 3.721 ± 1.197
1.55GlyHis: 1.55 ± 0.521
1.86GlyIle: 1.86 ± 0.679
2.171GlyLys: 2.171 ± 1.104
2.481GlyLeu: 2.481 ± 0.661
2.481GlyMet: 2.481 ± 1.254
1.24GlyAsn: 1.24 ± 0.57
1.86GlyPro: 1.86 ± 0.898
2.171GlyGln: 2.171 ± 0.734
3.721GlyArg: 3.721 ± 0.761
4.961GlySer: 4.961 ± 3.089
4.651GlyThr: 4.651 ± 1.71
1.55GlyVal: 1.55 ± 0.865
0.62GlyTrp: 0.62 ± 0.385
3.411GlyTyr: 3.411 ± 0.514
0.0GlyXaa: 0.0 ± 0.0
His
3.411HisAla: 3.411 ± 1.504
1.55HisCys: 1.55 ± 0.695
0.31HisAsp: 0.31 ± 0.518
1.55HisGlu: 1.55 ± 0.521
3.101HisPhe: 3.101 ± 1.231
1.86HisGly: 1.86 ± 0.527
0.31HisHis: 0.31 ± 0.193
1.55HisIle: 1.55 ± 0.648
0.62HisLys: 0.62 ± 0.305
2.171HisLeu: 2.171 ± 0.724
0.62HisMet: 0.62 ± 0.392
1.86HisAsn: 1.86 ± 0.745
0.93HisPro: 0.93 ± 0.565
3.101HisGln: 3.101 ± 0.969
0.62HisArg: 0.62 ± 0.333
3.721HisSer: 3.721 ± 1.661
1.24HisThr: 1.24 ± 0.77
0.62HisVal: 0.62 ± 0.4
0.0HisTrp: 0.0 ± 0.0
0.62HisTyr: 0.62 ± 0.4
0.0HisXaa: 0.0 ± 0.0
Ile
1.86IleAla: 1.86 ± 0.678
0.93IleCys: 0.93 ± 0.64
1.86IleAsp: 1.86 ± 1.038
1.86IleGlu: 1.86 ± 0.66
2.171IlePhe: 2.171 ± 0.673
0.93IleGly: 0.93 ± 0.578
2.791IleHis: 2.791 ± 0.579
1.55IleIle: 1.55 ± 0.926
2.171IleLys: 2.171 ± 0.871
5.581IleLeu: 5.581 ± 3.091
0.62IleMet: 0.62 ± 0.385
0.93IleAsn: 0.93 ± 0.631
1.24IlePro: 1.24 ± 0.502
1.55IleGln: 1.55 ± 0.743
3.411IleArg: 3.411 ± 0.708
3.101IleSer: 3.101 ± 1.031
2.791IleThr: 2.791 ± 0.499
3.721IleVal: 3.721 ± 0.628
0.31IleTrp: 0.31 ± 0.193
1.24IleTyr: 1.24 ± 0.407
0.0IleXaa: 0.0 ± 0.0
Lys
4.651LysAla: 4.651 ± 1.382
0.0LysCys: 0.0 ± 0.0
3.721LysAsp: 3.721 ± 1.09
1.24LysGlu: 1.24 ± 0.77
2.481LysPhe: 2.481 ± 0.585
1.24LysGly: 1.24 ± 0.627
0.93LysHis: 0.93 ± 0.578
1.86LysIle: 1.86 ± 0.841
1.86LysLys: 1.86 ± 1.155
6.512LysLeu: 6.512 ± 1.804
1.24LysMet: 1.24 ± 0.864
1.24LysAsn: 1.24 ± 0.666
5.271LysPro: 5.271 ± 2.017
1.55LysGln: 1.55 ± 0.721
4.031LysArg: 4.031 ± 1.076
2.171LysSer: 2.171 ± 1.104
3.721LysThr: 3.721 ± 1.02
2.171LysVal: 2.171 ± 0.705
0.62LysTrp: 0.62 ± 0.385
0.31LysTyr: 0.31 ± 0.193
0.0LysXaa: 0.0 ± 0.0
Leu
8.372LeuAla: 8.372 ± 1.337
2.481LeuCys: 2.481 ± 0.843
5.891LeuAsp: 5.891 ± 1.036
3.721LeuGlu: 3.721 ± 1.259
4.961LeuPhe: 4.961 ± 1.266
5.271LeuGly: 5.271 ± 1.028
3.101LeuHis: 3.101 ± 1.247
4.961LeuIle: 4.961 ± 1.627
3.411LeuLys: 3.411 ± 0.676
8.062LeuLeu: 8.062 ± 2.199
3.411LeuMet: 3.411 ± 1.653
0.93LeuAsn: 0.93 ± 0.498
6.512LeuPro: 6.512 ± 2.121
4.031LeuGln: 4.031 ± 1.203
6.512LeuArg: 6.512 ± 0.378
7.132LeuSer: 7.132 ± 1.002
8.062LeuThr: 8.062 ± 1.208
3.411LeuVal: 3.411 ± 0.724
0.93LeuTrp: 0.93 ± 0.429
3.101LeuTyr: 3.101 ± 1.124
0.0LeuXaa: 0.0 ± 0.0
Met
0.93MetAla: 0.93 ± 0.578
0.31MetCys: 0.31 ± 0.193
0.62MetAsp: 0.62 ± 0.305
0.93MetGlu: 0.93 ± 0.578
0.31MetPhe: 0.31 ± 0.353
0.93MetGly: 0.93 ± 0.767
0.31MetHis: 0.31 ± 0.518
1.24MetIle: 1.24 ± 0.627
0.31MetLys: 0.31 ± 0.335
0.93MetLeu: 0.93 ± 0.767
0.0MetMet: 0.0 ± 0.0
3.721MetAsn: 3.721 ± 1.571
2.481MetPro: 2.481 ± 1.254
0.62MetGln: 0.62 ± 0.385
1.86MetArg: 1.86 ± 0.693
1.86MetSer: 1.86 ± 0.677
2.171MetThr: 2.171 ± 0.679
1.55MetVal: 1.55 ± 1.108
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
6.202AsnAla: 6.202 ± 2.32
0.31AsnCys: 0.31 ± 0.193
4.341AsnAsp: 4.341 ± 1.955
2.171AsnGlu: 2.171 ± 0.5
0.93AsnPhe: 0.93 ± 0.368
2.791AsnGly: 2.791 ± 1.943
1.86AsnHis: 1.86 ± 1.136
2.171AsnIle: 2.171 ± 0.824
2.791AsnLys: 2.791 ± 0.66
3.101AsnLeu: 3.101 ± 1.133
2.171AsnMet: 2.171 ± 1.388
2.171AsnAsn: 2.171 ± 1.023
3.101AsnPro: 3.101 ± 1.089
1.55AsnGln: 1.55 ± 1.003
1.86AsnArg: 1.86 ± 0.794
3.411AsnSer: 3.411 ± 2.274
2.791AsnThr: 2.791 ± 1.028
3.721AsnVal: 3.721 ± 0.893
0.93AsnTrp: 0.93 ± 0.767
1.24AsnTyr: 1.24 ± 0.77
0.0AsnXaa: 0.0 ± 0.0
Pro
5.581ProAla: 5.581 ± 1.057
0.93ProCys: 0.93 ± 0.767
2.481ProAsp: 2.481 ± 1.244
3.721ProGlu: 3.721 ± 1.682
2.171ProPhe: 2.171 ± 0.831
2.791ProGly: 2.791 ± 0.634
3.411ProHis: 3.411 ± 0.915
1.24ProIle: 1.24 ± 0.77
4.341ProLys: 4.341 ± 0.909
5.271ProLeu: 5.271 ± 1.262
1.24ProMet: 1.24 ± 0.864
4.961ProAsn: 4.961 ± 1.391
10.233ProPro: 10.233 ± 3.186
3.411ProGln: 3.411 ± 0.514
1.86ProArg: 1.86 ± 0.965
2.791ProSer: 2.791 ± 1.316
6.822ProThr: 6.822 ± 2.09
4.031ProVal: 4.031 ± 0.714
0.31ProTrp: 0.31 ± 0.193
0.93ProTyr: 0.93 ± 0.429
0.0ProXaa: 0.0 ± 0.0
Gln
3.101GlnAla: 3.101 ± 1.389
0.31GlnCys: 0.31 ± 0.518
2.791GlnAsp: 2.791 ± 0.903
1.55GlnGlu: 1.55 ± 0.743
1.86GlnPhe: 1.86 ± 0.558
2.791GlnGly: 2.791 ± 1.034
0.31GlnHis: 0.31 ± 0.353
2.791GlnIle: 2.791 ± 0.66
0.93GlnLys: 0.93 ± 0.368
4.961GlnLeu: 4.961 ± 0.933
0.0GlnMet: 0.0 ± 0.0
4.651GlnAsn: 4.651 ± 2.084
3.411GlnPro: 3.411 ± 0.789
4.031GlnGln: 4.031 ± 1.76
2.791GlnArg: 2.791 ± 0.832
5.891GlnSer: 5.891 ± 0.744
2.481GlnThr: 2.481 ± 0.604
1.86GlnVal: 1.86 ± 0.841
0.62GlnTrp: 0.62 ± 0.385
0.93GlnTyr: 0.93 ± 0.578
0.0GlnXaa: 0.0 ± 0.0
Arg
6.512ArgAla: 6.512 ± 1.023
1.24ArgCys: 1.24 ± 0.759
3.721ArgAsp: 3.721 ± 1.191
4.961ArgGlu: 4.961 ± 0.672
2.791ArgPhe: 2.791 ± 1.136
1.86ArgGly: 1.86 ± 0.735
0.93ArgHis: 0.93 ± 0.578
1.55ArgIle: 1.55 ± 0.63
1.55ArgLys: 1.55 ± 0.521
6.202ArgLeu: 6.202 ± 1.179
0.0ArgMet: 0.0 ± 0.0
1.24ArgAsn: 1.24 ± 0.576
6.202ArgPro: 6.202 ± 1.462
4.651ArgGln: 4.651 ± 1.562
5.581ArgArg: 5.581 ± 1.505
3.721ArgSer: 3.721 ± 1.62
4.651ArgThr: 4.651 ± 0.956
2.171ArgVal: 2.171 ± 0.869
0.0ArgTrp: 0.0 ± 0.0
1.55ArgTyr: 1.55 ± 0.69
0.0ArgXaa: 0.0 ± 0.0
Ser
2.171SerAla: 2.171 ± 0.859
0.31SerCys: 0.31 ± 0.353
7.132SerAsp: 7.132 ± 1.126
4.341SerGlu: 4.341 ± 1.771
0.93SerPhe: 0.93 ± 0.464
4.031SerGly: 4.031 ± 0.411
2.481SerHis: 2.481 ± 0.931
1.86SerIle: 1.86 ± 0.54
3.101SerLys: 3.101 ± 0.78
5.891SerLeu: 5.891 ± 0.81
0.93SerMet: 0.93 ± 0.767
4.961SerAsn: 4.961 ± 1.919
5.271SerPro: 5.271 ± 1.031
4.031SerGln: 4.031 ± 0.742
7.752SerArg: 7.752 ± 3.655
9.302SerSer: 9.302 ± 3.775
4.961SerThr: 4.961 ± 0.822
3.721SerVal: 3.721 ± 0.713
0.31SerTrp: 0.31 ± 0.193
1.55SerTyr: 1.55 ± 0.398
0.0SerXaa: 0.0 ± 0.0
Thr
5.581ThrAla: 5.581 ± 0.922
1.55ThrCys: 1.55 ± 0.521
2.791ThrAsp: 2.791 ± 0.95
2.171ThrGlu: 2.171 ± 0.789
3.411ThrPhe: 3.411 ± 0.378
3.721ThrGly: 3.721 ± 0.945
2.791ThrHis: 2.791 ± 1.118
3.101ThrIle: 3.101 ± 0.908
2.481ThrLys: 2.481 ± 0.961
9.922ThrLeu: 9.922 ± 1.31
0.62ThrMet: 0.62 ± 0.385
6.822ThrAsn: 6.822 ± 2.09
4.031ThrPro: 4.031 ± 0.463
0.93ThrGln: 0.93 ± 0.578
5.581ThrArg: 5.581 ± 1.5
4.341ThrSer: 4.341 ± 1.102
6.512ThrThr: 6.512 ± 1.377
4.341ThrVal: 4.341 ± 1.021
0.0ThrTrp: 0.0 ± 0.0
2.481ThrTyr: 2.481 ± 0.701
0.0ThrXaa: 0.0 ± 0.0
Val
2.481ValAla: 2.481 ± 0.613
0.31ValCys: 0.31 ± 0.391
3.101ValAsp: 3.101 ± 1.33
5.581ValGlu: 5.581 ± 1.399
1.55ValPhe: 1.55 ± 0.721
2.171ValGly: 2.171 ± 0.604
0.93ValHis: 0.93 ± 0.402
2.791ValIle: 2.791 ± 0.867
3.101ValLys: 3.101 ± 1.212
4.961ValLeu: 4.961 ± 1.243
0.93ValMet: 0.93 ± 0.578
2.791ValAsn: 2.791 ± 0.302
3.101ValPro: 3.101 ± 0.764
1.55ValGln: 1.55 ± 0.743
2.791ValArg: 2.791 ± 0.585
2.791ValSer: 2.791 ± 0.982
6.202ValThr: 6.202 ± 1.254
1.86ValVal: 1.86 ± 0.921
0.31ValTrp: 0.31 ± 0.193
1.55ValTyr: 1.55 ± 0.93
0.0ValXaa: 0.0 ± 0.0
Trp
0.31TrpAla: 0.31 ± 0.193
0.0TrpCys: 0.0 ± 0.0
0.31TrpAsp: 0.31 ± 0.193
0.0TrpGlu: 0.0 ± 0.0
0.31TrpPhe: 0.31 ± 0.193
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.62TrpLys: 0.62 ± 0.385
0.62TrpLeu: 0.62 ± 0.305
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.31TrpPro: 0.31 ± 0.193
0.0TrpGln: 0.0 ± 0.0
0.62TrpArg: 0.62 ± 0.333
1.55TrpSer: 1.55 ± 0.521
1.24TrpThr: 1.24 ± 0.627
0.93TrpVal: 0.93 ± 0.578
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.031TyrAla: 4.031 ± 0.843
1.55TyrCys: 1.55 ± 0.537
2.171TyrAsp: 2.171 ± 1.023
1.24TyrGlu: 1.24 ± 0.576
0.31TyrPhe: 0.31 ± 0.434
2.481TyrGly: 2.481 ± 0.805
1.55TyrHis: 1.55 ± 0.687
1.55TyrIle: 1.55 ± 0.828
1.24TyrLys: 1.24 ± 0.61
3.101TyrLeu: 3.101 ± 1.089
0.31TyrMet: 0.31 ± 0.193
0.93TyrAsn: 0.93 ± 0.548
1.24TyrPro: 1.24 ± 0.77
2.481TyrGln: 2.481 ± 0.415
1.55TyrArg: 1.55 ± 0.742
0.62TyrSer: 0.62 ± 0.333
1.55TyrThr: 1.55 ± 0.551
2.171TyrVal: 2.171 ± 0.5
0.0TyrTrp: 0.0 ± 0.0
0.62TyrTyr: 0.62 ± 0.385
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (3226 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski