Amino acid dipepetide frequency for Itaporanga virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.886AlaAla: 4.886 ± 4.39
3.343AlaCys: 3.343 ± 0.793
2.571AlaAsp: 2.571 ± 0.539
4.114AlaGlu: 4.114 ± 1.814
1.029AlaPhe: 1.029 ± 1.411
2.314AlaGly: 2.314 ± 0.691
2.571AlaHis: 2.571 ± 1.127
4.114AlaIle: 4.114 ± 0.878
3.6AlaLys: 3.6 ± 0.928
3.086AlaLeu: 3.086 ± 1.225
0.771AlaMet: 0.771 ± 0.473
1.543AlaAsn: 1.543 ± 0.582
1.8AlaPro: 1.8 ± 0.366
2.828AlaGln: 2.828 ± 0.802
3.086AlaArg: 3.086 ± 1.139
5.143AlaSer: 5.143 ± 1.628
3.857AlaThr: 3.857 ± 1.61
3.857AlaVal: 3.857 ± 1.175
0.514AlaTrp: 0.514 ± 0.164
0.771AlaTyr: 0.771 ± 1.471
0.0AlaXaa: 0.0 ± 0.0
Cys
1.286CysAla: 1.286 ± 1.054
0.514CysCys: 0.514 ± 0.315
1.286CysAsp: 1.286 ± 0.516
1.8CysGlu: 1.8 ± 0.532
2.314CysPhe: 2.314 ± 1.438
1.286CysGly: 1.286 ± 0.502
1.029CysHis: 1.029 ± 0.785
1.543CysIle: 1.543 ± 0.851
2.571CysLys: 2.571 ± 0.736
1.8CysLeu: 1.8 ± 0.901
0.514CysMet: 0.514 ± 0.315
0.771CysAsn: 0.771 ± 0.239
1.286CysPro: 1.286 ± 0.502
0.514CysGln: 0.514 ± 0.164
1.543CysArg: 1.543 ± 0.838
2.057CysSer: 2.057 ± 0.849
2.314CysThr: 2.314 ± 0.492
1.543CysVal: 1.543 ± 1.012
0.0CysTrp: 0.0 ± 0.0
2.057CysTyr: 2.057 ± 1.114
0.0CysXaa: 0.0 ± 0.0
Asp
2.828AspAla: 2.828 ± 1.134
1.543AspCys: 1.543 ± 0.838
4.628AspAsp: 4.628 ± 1.035
4.371AspGlu: 4.371 ± 1.023
2.828AspPhe: 2.828 ± 0.942
2.571AspGly: 2.571 ± 0.757
1.286AspHis: 1.286 ± 0.378
3.086AspIle: 3.086 ± 0.501
3.857AspLys: 3.857 ± 0.788
5.143AspLeu: 5.143 ± 1.589
2.314AspMet: 2.314 ± 1.104
1.543AspAsn: 1.543 ± 0.354
2.828AspPro: 2.828 ± 0.607
0.771AspGln: 0.771 ± 0.416
2.314AspArg: 2.314 ± 0.822
5.143AspSer: 5.143 ± 1.937
2.057AspThr: 2.057 ± 0.664
3.857AspVal: 3.857 ± 0.657
1.286AspTrp: 1.286 ± 0.362
1.8AspTyr: 1.8 ± 0.62
0.0AspXaa: 0.0 ± 0.0
Glu
3.343GluAla: 3.343 ± 0.664
1.286GluCys: 1.286 ± 0.362
2.828GluAsp: 2.828 ± 1.562
7.457GluGlu: 7.457 ± 2.39
3.086GluPhe: 3.086 ± 0.95
4.371GluGly: 4.371 ± 0.382
0.514GluHis: 0.514 ± 0.315
6.428GluIle: 6.428 ± 1.859
4.371GluLys: 4.371 ± 1.623
5.143GluLeu: 5.143 ± 0.521
2.571GluMet: 2.571 ± 1.485
2.314GluAsn: 2.314 ± 1.121
1.543GluPro: 1.543 ± 0.668
1.543GluGln: 1.543 ± 0.668
1.8GluArg: 1.8 ± 0.462
4.886GluSer: 4.886 ± 1.274
3.857GluThr: 3.857 ± 1.053
4.371GluVal: 4.371 ± 1.031
1.543GluTrp: 1.543 ± 0.838
2.828GluTyr: 2.828 ± 0.539
0.0GluXaa: 0.0 ± 0.0
Phe
2.828PheAla: 2.828 ± 1.841
1.543PheCys: 1.543 ± 0.699
2.057PheAsp: 2.057 ± 0.807
2.057PheGlu: 2.057 ± 0.42
2.314PhePhe: 2.314 ± 0.437
2.571PheGly: 2.571 ± 1.266
1.286PheHis: 1.286 ± 0.362
2.057PheIle: 2.057 ± 0.87
2.571PheLys: 2.571 ± 1.033
4.628PheLeu: 4.628 ± 0.453
1.543PheMet: 1.543 ± 0.809
2.828PheAsn: 2.828 ± 0.847
1.8PhePro: 1.8 ± 0.822
1.286PheGln: 1.286 ± 0.728
2.828PheArg: 2.828 ± 0.847
3.6PheSer: 3.6 ± 0.853
2.828PheThr: 2.828 ± 0.971
3.6PheVal: 3.6 ± 0.525
0.771PheTrp: 0.771 ± 0.239
0.771PheTyr: 0.771 ± 0.968
0.0PheXaa: 0.0 ± 0.0
Gly
3.6GlyAla: 3.6 ± 0.732
2.057GlyCys: 2.057 ± 0.626
3.343GlyAsp: 3.343 ± 1.052
3.6GlyGlu: 3.6 ± 0.803
4.114GlyPhe: 4.114 ± 1.39
5.914GlyGly: 5.914 ± 1.243
1.543GlyHis: 1.543 ± 0.354
1.543GlyIle: 1.543 ± 0.545
3.6GlyLys: 3.6 ± 0.986
5.657GlyLeu: 5.657 ± 0.824
1.8GlyMet: 1.8 ± 0.596
2.571GlyAsn: 2.571 ± 2.32
3.6GlyPro: 3.6 ± 1.445
1.286GlyGln: 1.286 ± 0.502
2.057GlyArg: 2.057 ± 1.089
7.971GlySer: 7.971 ± 0.989
2.057GlyThr: 2.057 ± 0.656
4.886GlyVal: 4.886 ± 1.5
0.514GlyTrp: 0.514 ± 0.164
1.8GlyTyr: 1.8 ± 0.641
0.0GlyXaa: 0.0 ± 0.0
His
0.771HisAla: 0.771 ± 0.349
0.771HisCys: 0.771 ± 0.349
0.514HisAsp: 0.514 ± 0.315
0.514HisGlu: 0.514 ± 0.164
1.286HisPhe: 1.286 ± 0.502
2.057HisGly: 2.057 ± 0.439
0.257HisHis: 0.257 ± 0.216
2.057HisIle: 2.057 ± 0.611
1.286HisLys: 1.286 ± 0.573
1.8HisLeu: 1.8 ± 0.532
0.514HisMet: 0.514 ± 0.428
0.771HisAsn: 0.771 ± 0.647
1.029HisPro: 1.029 ± 0.85
0.771HisGln: 0.771 ± 0.473
2.057HisArg: 2.057 ± 1.114
1.543HisSer: 1.543 ± 0.486
1.8HisThr: 1.8 ± 0.461
1.8HisVal: 1.8 ± 0.821
0.0HisTrp: 0.0 ± 0.0
1.029HisTyr: 1.029 ± 0.328
0.0HisXaa: 0.0 ± 0.0
Ile
3.857IleAla: 3.857 ± 1.733
0.771IleCys: 0.771 ± 0.473
4.114IleAsp: 4.114 ± 0.893
2.828IleGlu: 2.828 ± 1.445
2.057IlePhe: 2.057 ± 0.611
4.628IleGly: 4.628 ± 1.021
1.029IleHis: 1.029 ± 0.37
3.6IleIle: 3.6 ± 1.149
4.114IleLys: 4.114 ± 0.875
6.686IleLeu: 6.686 ± 2.038
0.771IleMet: 0.771 ± 0.239
2.057IleAsn: 2.057 ± 0.535
1.8IlePro: 1.8 ± 0.901
2.057IleGln: 2.057 ± 0.73
5.4IleArg: 5.4 ± 1.269
6.943IleSer: 6.943 ± 2.589
3.6IleThr: 3.6 ± 0.996
4.628IleVal: 4.628 ± 0.237
0.514IleTrp: 0.514 ± 0.315
1.543IleTyr: 1.543 ± 0.668
0.0IleXaa: 0.0 ± 0.0
Lys
5.4LysAla: 5.4 ± 1.596
1.543LysCys: 1.543 ± 0.699
2.828LysAsp: 2.828 ± 1.174
5.143LysGlu: 5.143 ± 0.518
2.828LysPhe: 2.828 ± 1.868
3.857LysGly: 3.857 ± 1.854
1.029LysHis: 1.029 ± 0.37
3.343LysIle: 3.343 ± 0.7
4.371LysLys: 4.371 ± 1.199
5.4LysLeu: 5.4 ± 0.966
2.571LysMet: 2.571 ± 1.218
2.057LysAsn: 2.057 ± 0.74
2.828LysPro: 2.828 ± 0.851
1.029LysGln: 1.029 ± 0.631
2.314LysArg: 2.314 ± 1.121
5.143LysSer: 5.143 ± 1.083
3.6LysThr: 3.6 ± 1.085
5.4LysVal: 5.4 ± 0.947
1.286LysTrp: 1.286 ± 0.789
1.543LysTyr: 1.543 ± 0.668
0.0LysXaa: 0.0 ± 0.0
Leu
5.143LeuAla: 5.143 ± 1.44
2.057LeuCys: 2.057 ± 0.611
3.6LeuAsp: 3.6 ± 0.839
5.143LeuGlu: 5.143 ± 1.167
5.143LeuPhe: 5.143 ± 1.399
5.914LeuGly: 5.914 ± 1.488
2.057LeuHis: 2.057 ± 0.42
7.714LeuIle: 7.714 ± 1.924
5.4LeuLys: 5.4 ± 0.93
6.943LeuLeu: 6.943 ± 2.093
1.286LeuMet: 1.286 ± 0.362
3.6LeuAsn: 3.6 ± 2.375
2.828LeuPro: 2.828 ± 1.287
2.314LeuGln: 2.314 ± 1.133
5.657LeuArg: 5.657 ± 0.802
7.971LeuSer: 7.971 ± 0.951
4.886LeuThr: 4.886 ± 2.258
5.143LeuVal: 5.143 ± 2.073
0.257LeuTrp: 0.257 ± 0.484
3.086LeuTyr: 3.086 ± 0.257
0.0LeuXaa: 0.0 ± 0.0
Met
0.771MetAla: 0.771 ± 0.239
0.0MetCys: 0.0 ± 0.0
3.086MetAsp: 3.086 ± 0.95
1.286MetGlu: 1.286 ± 0.789
1.286MetPhe: 1.286 ± 0.516
2.057MetGly: 2.057 ± 1.195
0.771MetHis: 0.771 ± 0.688
3.086MetIle: 3.086 ± 1.245
1.8MetLys: 1.8 ± 0.641
1.8MetLeu: 1.8 ± 1.053
2.057MetMet: 2.057 ± 0.648
1.8MetAsn: 1.8 ± 0.756
1.8MetPro: 1.8 ± 1.031
0.771MetGln: 0.771 ± 0.473
1.543MetArg: 1.543 ± 0.69
1.8MetSer: 1.8 ± 1.26
0.514MetThr: 0.514 ± 0.315
1.8MetVal: 1.8 ± 0.603
0.0MetTrp: 0.0 ± 0.0
0.257MetTyr: 0.257 ± 0.158
0.0MetXaa: 0.0 ± 0.0
Asn
2.057AsnAla: 2.057 ± 0.73
1.286AsnCys: 1.286 ± 0.965
1.8AsnAsp: 1.8 ± 1.108
1.286AsnGlu: 1.286 ± 0.789
2.057AsnPhe: 2.057 ± 0.74
1.543AsnGly: 1.543 ± 0.43
0.257AsnHis: 0.257 ± 0.158
1.543AsnIle: 1.543 ± 0.478
2.828AsnLys: 2.828 ± 1.164
4.628AsnLeu: 4.628 ± 1.419
1.286AsnMet: 1.286 ± 0.417
0.771AsnAsn: 0.771 ± 0.649
3.086AsnPro: 3.086 ± 2.26
1.029AsnGln: 1.029 ± 0.37
2.828AsnArg: 2.828 ± 1.029
3.857AsnSer: 3.857 ± 0.741
1.8AsnThr: 1.8 ± 0.905
1.543AsnVal: 1.543 ± 0.545
0.257AsnTrp: 0.257 ± 0.767
1.286AsnTyr: 1.286 ± 0.762
0.0AsnXaa: 0.0 ± 0.0
Pro
2.571ProAla: 2.571 ± 0.387
0.514ProCys: 0.514 ± 0.432
2.828ProAsp: 2.828 ± 0.607
4.114ProGlu: 4.114 ± 1.687
1.543ProPhe: 1.543 ± 0.699
3.857ProGly: 3.857 ± 0.885
0.514ProHis: 0.514 ± 0.315
1.8ProIle: 1.8 ± 0.659
2.571ProLys: 2.571 ± 0.821
4.114ProLeu: 4.114 ± 1.021
0.257ProMet: 0.257 ± 0.216
1.543ProAsn: 1.543 ± 0.604
1.8ProPro: 1.8 ± 0.717
1.029ProGln: 1.029 ± 0.557
1.543ProArg: 1.543 ± 1.157
4.371ProSer: 4.371 ± 1.256
2.571ProThr: 2.571 ± 0.387
3.086ProVal: 3.086 ± 0.485
0.771ProTrp: 0.771 ± 0.473
1.543ProTyr: 1.543 ± 0.478
0.0ProXaa: 0.0 ± 0.0
Gln
1.8GlnAla: 1.8 ± 1.006
1.286GlnCys: 1.286 ± 0.502
1.029GlnAsp: 1.029 ± 0.328
2.314GlnGlu: 2.314 ± 0.84
0.257GlnPhe: 0.257 ± 0.158
2.571GlnGly: 2.571 ± 0.668
0.771GlnHis: 0.771 ± 0.473
2.057GlnIle: 2.057 ± 0.74
2.571GlnLys: 2.571 ± 0.839
2.571GlnLeu: 2.571 ± 1.033
1.286GlnMet: 1.286 ± 0.547
0.257GlnAsn: 0.257 ± 0.216
1.8GlnPro: 1.8 ± 0.641
1.029GlnGln: 1.029 ± 0.7
1.8GlnArg: 1.8 ± 0.461
2.057GlnSer: 2.057 ± 0.611
1.286GlnThr: 1.286 ± 0.378
2.057GlnVal: 2.057 ± 1.001
0.0GlnTrp: 0.0 ± 0.0
0.514GlnTyr: 0.514 ± 0.315
0.0GlnXaa: 0.0 ± 0.0
Arg
3.343ArgAla: 3.343 ± 0.7
2.057ArgCys: 2.057 ± 1.526
3.857ArgAsp: 3.857 ± 1.704
5.143ArgGlu: 5.143 ± 1.519
1.543ArgPhe: 1.543 ± 0.691
4.886ArgGly: 4.886 ± 1.8
0.514ArgHis: 0.514 ± 0.315
3.086ArgIle: 3.086 ± 0.626
2.571ArgLys: 2.571 ± 0.932
4.371ArgLeu: 4.371 ± 1.566
1.286ArgMet: 1.286 ± 0.516
1.543ArgAsn: 1.543 ± 0.354
0.771ArgPro: 0.771 ± 0.349
1.543ArgGln: 1.543 ± 0.478
0.771ArgArg: 0.771 ± 0.473
3.857ArgSer: 3.857 ± 1.135
3.857ArgThr: 3.857 ± 1.016
4.371ArgVal: 4.371 ± 1.296
1.029ArgTrp: 1.029 ± 0.37
1.543ArgTyr: 1.543 ± 0.478
0.0ArgXaa: 0.0 ± 0.0
Ser
3.086SerAla: 3.086 ± 0.909
3.6SerCys: 3.6 ± 2.704
7.457SerAsp: 7.457 ± 1.452
3.857SerGlu: 3.857 ± 0.741
6.428SerPhe: 6.428 ± 1.562
6.428SerGly: 6.428 ± 1.748
3.086SerHis: 3.086 ± 1.16
4.886SerIle: 4.886 ± 0.359
5.914SerLys: 5.914 ± 0.382
7.457SerLeu: 7.457 ± 1.452
2.057SerMet: 2.057 ± 0.439
3.343SerAsn: 3.343 ± 0.412
5.4SerPro: 5.4 ± 0.306
2.314SerGln: 2.314 ± 0.437
5.143SerArg: 5.143 ± 1.165
10.028SerSer: 10.028 ± 1.983
5.143SerThr: 5.143 ± 0.852
5.143SerVal: 5.143 ± 0.376
2.057SerTrp: 2.057 ± 0.439
2.057SerTyr: 2.057 ± 0.989
0.0SerXaa: 0.0 ± 0.0
Thr
2.057ThrAla: 2.057 ± 0.42
1.543ThrCys: 1.543 ± 1.388
2.571ThrAsp: 2.571 ± 0.757
4.628ThrGlu: 4.628 ± 0.237
2.057ThrPhe: 2.057 ± 0.73
4.628ThrGly: 4.628 ± 0.674
1.029ThrHis: 1.029 ± 0.37
3.857ThrIle: 3.857 ± 1.306
2.828ThrLys: 2.828 ± 1.842
5.657ThrLeu: 5.657 ± 1.581
1.029ThrMet: 1.029 ± 1.422
2.828ThrAsn: 2.828 ± 0.412
2.314ThrPro: 2.314 ± 0.691
2.057ThrGln: 2.057 ± 0.611
2.828ThrArg: 2.828 ± 0.79
5.4ThrSer: 5.4 ± 0.538
4.371ThrThr: 4.371 ± 1.399
3.086ThrVal: 3.086 ± 0.702
0.514ThrTrp: 0.514 ± 0.74
1.543ThrTyr: 1.543 ± 0.582
0.0ThrXaa: 0.0 ± 0.0
Val
5.143ValAla: 5.143 ± 1.91
2.057ValCys: 2.057 ± 1.114
3.086ValAsp: 3.086 ± 1.131
4.628ValGlu: 4.628 ± 0.944
1.8ValPhe: 1.8 ± 0.366
1.029ValGly: 1.029 ± 0.557
1.543ValHis: 1.543 ± 0.699
4.371ValIle: 4.371 ± 0.297
4.886ValLys: 4.886 ± 0.61
5.143ValLeu: 5.143 ± 0.376
2.314ValMet: 2.314 ± 1.104
2.828ValAsn: 2.828 ± 1.116
2.314ValPro: 2.314 ± 0.559
3.6ValGln: 3.6 ± 1.004
3.857ValArg: 3.857 ± 1.053
8.228ValSer: 8.228 ± 0.595
3.857ValThr: 3.857 ± 1.601
4.371ValVal: 4.371 ± 1.114
0.257ValTrp: 0.257 ± 0.216
2.057ValTyr: 2.057 ± 0.439
0.0ValXaa: 0.0 ± 0.0
Trp
0.257TrpAla: 0.257 ± 0.158
0.0TrpCys: 0.0 ± 0.0
0.771TrpAsp: 0.771 ± 0.239
0.257TrpGlu: 0.257 ± 0.158
0.257TrpPhe: 0.257 ± 0.158
1.029TrpGly: 1.029 ± 0.357
0.0TrpHis: 0.0 ± 0.0
1.029TrpIle: 1.029 ± 0.37
0.0TrpLys: 0.0 ± 0.0
1.543TrpLeu: 1.543 ± 0.354
1.029TrpMet: 1.029 ± 0.37
0.771TrpAsn: 0.771 ± 0.239
0.514TrpPro: 0.514 ± 0.428
0.257TrpGln: 0.257 ± 0.767
0.771TrpArg: 0.771 ± 0.239
0.771TrpSer: 0.771 ± 0.349
1.286TrpThr: 1.286 ± 0.762
0.771TrpVal: 0.771 ± 0.349
0.257TrpTrp: 0.257 ± 0.158
0.257TrpTyr: 0.257 ± 0.158
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.771TyrAla: 0.771 ± 0.649
0.257TyrCys: 0.257 ± 0.158
1.8TyrAsp: 1.8 ± 0.651
1.543TyrGlu: 1.543 ± 0.486
1.543TyrPhe: 1.543 ± 0.946
0.257TyrGly: 0.257 ± 0.158
1.543TyrHis: 1.543 ± 0.43
1.8TyrIle: 1.8 ± 0.536
1.8TyrLys: 1.8 ± 1.227
2.571TyrLeu: 2.571 ± 1.064
0.771TyrMet: 0.771 ± 0.473
1.286TyrAsn: 1.286 ± 0.516
1.8TyrPro: 1.8 ± 0.717
1.286TyrGln: 1.286 ± 0.563
1.8TyrArg: 1.8 ± 0.532
4.114TyrSer: 4.114 ± 1.501
1.286TyrThr: 1.286 ± 0.502
2.057TyrVal: 2.057 ± 0.42
0.0TyrTrp: 0.0 ± 0.0
0.771TyrTyr: 0.771 ± 0.416
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3890 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski