Amino acid dipepetide frequency for Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco s disease virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.927AlaAla: 18.927 ± 1.439
2.304AlaCys: 2.304 ± 0.219
6.144AlaAsp: 6.144 ± 0.552
7.184AlaGlu: 7.184 ± 0.555
3.666AlaPhe: 3.666 ± 0.278
7.556AlaGly: 7.556 ± 0.409
2.428AlaHis: 2.428 ± 0.236
3.939AlaIle: 3.939 ± 0.31
4.112AlaLys: 4.112 ± 0.502
10.157AlaLeu: 10.157 ± 0.697
2.651AlaMet: 2.651 ± 0.254
3.642AlaAsn: 3.642 ± 0.304
7.432AlaPro: 7.432 ± 0.698
3.245AlaGln: 3.245 ± 0.281
8.398AlaArg: 8.398 ± 0.524
8.522AlaSer: 8.522 ± 0.478
6.169AlaThr: 6.169 ± 0.539
8.051AlaVal: 8.051 ± 0.409
1.685AlaTrp: 1.685 ± 0.214
2.849AlaTyr: 2.849 ± 0.268
0.0AlaXaa: 0.0 ± 0.0
Cys
3.196CysAla: 3.196 ± 0.333
0.545CysCys: 0.545 ± 0.134
1.115CysAsp: 1.115 ± 0.192
1.164CysGlu: 1.164 ± 0.134
0.669CysPhe: 0.669 ± 0.119
1.511CysGly: 1.511 ± 0.154
0.421CysHis: 0.421 ± 0.092
0.718CysIle: 0.718 ± 0.142
0.595CysLys: 0.595 ± 0.095
2.106CysLeu: 2.106 ± 0.239
0.471CysMet: 0.471 ± 0.1
0.297CysAsn: 0.297 ± 0.084
1.09CysPro: 1.09 ± 0.2
0.347CysGln: 0.347 ± 0.082
1.635CysArg: 1.635 ± 0.223
1.61CysSer: 1.61 ± 0.242
0.644CysThr: 0.644 ± 0.122
1.561CysVal: 1.561 ± 0.189
0.223CysTrp: 0.223 ± 0.07
0.57CysTyr: 0.57 ± 0.093
0.0CysXaa: 0.0 ± 0.0
Asp
6.837AspAla: 6.837 ± 0.513
1.14AspCys: 1.14 ± 0.142
4.806AspAsp: 4.806 ± 0.418
4.286AspGlu: 4.286 ± 0.395
1.585AspPhe: 1.585 ± 0.23
4.41AspGly: 4.41 ± 0.405
1.288AspHis: 1.288 ± 0.175
1.784AspIle: 1.784 ± 0.212
2.279AspLys: 2.279 ± 0.245
4.88AspLeu: 4.88 ± 0.368
1.387AspMet: 1.387 ± 0.166
1.04AspAsn: 1.04 ± 0.116
3.741AspPro: 3.741 ± 0.336
1.09AspGln: 1.09 ± 0.148
3.79AspArg: 3.79 ± 0.314
4.187AspSer: 4.187 ± 0.31
2.824AspThr: 2.824 ± 0.385
3.989AspVal: 3.989 ± 0.288
0.595AspTrp: 0.595 ± 0.123
1.635AspTyr: 1.635 ± 0.175
0.0AspXaa: 0.0 ± 0.0
Glu
6.441GluAla: 6.441 ± 0.483
1.016GluCys: 1.016 ± 0.173
4.732GluAsp: 4.732 ± 0.353
4.36GluGlu: 4.36 ± 0.369
1.957GluPhe: 1.957 ± 0.188
2.948GluGly: 2.948 ± 0.253
1.412GluHis: 1.412 ± 0.161
2.378GluIle: 2.378 ± 0.274
2.329GluLys: 2.329 ± 0.378
5.747GluLeu: 5.747 ± 0.42
1.313GluMet: 1.313 ± 0.18
1.858GluAsn: 1.858 ± 0.201
2.898GluPro: 2.898 ± 0.319
1.709GluGln: 1.709 ± 0.189
4.806GluArg: 4.806 ± 0.484
3.741GluSer: 3.741 ± 0.293
4.137GluThr: 4.137 ± 0.25
2.477GluVal: 2.477 ± 0.235
0.471GluTrp: 0.471 ± 0.097
1.784GluTyr: 1.784 ± 0.176
0.0GluXaa: 0.0 ± 0.0
Phe
4.112PheAla: 4.112 ± 0.302
0.892PheCys: 0.892 ± 0.138
2.254PheAsp: 2.254 ± 0.23
1.932PheGlu: 1.932 ± 0.262
2.056PhePhe: 2.056 ± 0.222
2.552PheGly: 2.552 ± 0.282
0.768PheHis: 0.768 ± 0.149
1.016PheIle: 1.016 ± 0.177
1.214PheLys: 1.214 ± 0.215
4.063PheLeu: 4.063 ± 0.257
0.966PheMet: 0.966 ± 0.127
0.991PheAsn: 0.991 ± 0.183
2.106PhePro: 2.106 ± 0.247
0.694PheGln: 0.694 ± 0.115
1.585PheArg: 1.585 ± 0.244
2.775PheSer: 2.775 ± 0.242
1.734PheThr: 1.734 ± 0.259
3.047PheVal: 3.047 ± 0.304
0.322PheTrp: 0.322 ± 0.109
1.437PheTyr: 1.437 ± 0.237
0.0PheXaa: 0.0 ± 0.0
Gly
8.398GlyAla: 8.398 ± 0.445
1.239GlyCys: 1.239 ± 0.216
4.608GlyAsp: 4.608 ± 0.379
4.335GlyGlu: 4.335 ± 0.419
2.353GlyPhe: 2.353 ± 0.226
6.367GlyGly: 6.367 ± 0.466
1.263GlyHis: 1.263 ± 0.152
2.502GlyIle: 2.502 ± 0.276
2.923GlyLys: 2.923 ± 0.324
5.5GlyLeu: 5.5 ± 0.425
1.511GlyMet: 1.511 ± 0.163
2.403GlyAsn: 2.403 ± 0.261
3.419GlyPro: 3.419 ± 0.281
1.883GlyGln: 1.883 ± 0.199
5.202GlyArg: 5.202 ± 0.518
4.93GlySer: 4.93 ± 0.407
3.939GlyThr: 3.939 ± 0.301
4.162GlyVal: 4.162 ± 0.254
0.743GlyTrp: 0.743 ± 0.119
1.66GlyTyr: 1.66 ± 0.196
0.0GlyXaa: 0.0 ± 0.0
His
2.403HisAla: 2.403 ± 0.204
0.198HisCys: 0.198 ± 0.079
1.288HisAsp: 1.288 ± 0.18
1.486HisGlu: 1.486 ± 0.18
0.694HisPhe: 0.694 ± 0.109
2.131HisGly: 2.131 ± 0.23
0.446HisHis: 0.446 ± 0.11
0.917HisIle: 0.917 ± 0.149
0.793HisLys: 0.793 ± 0.118
1.66HisLeu: 1.66 ± 0.198
0.52HisMet: 0.52 ± 0.126
0.471HisAsn: 0.471 ± 0.12
0.966HisPro: 0.966 ± 0.161
0.718HisGln: 0.718 ± 0.123
1.313HisArg: 1.313 ± 0.152
1.313HisSer: 1.313 ± 0.187
1.016HisThr: 1.016 ± 0.182
1.585HisVal: 1.585 ± 0.3
0.173HisTrp: 0.173 ± 0.069
0.495HisTyr: 0.495 ± 0.096
0.0HisXaa: 0.0 ± 0.0
Ile
3.691IleAla: 3.691 ± 0.309
0.793IleCys: 0.793 ± 0.147
2.527IleAsp: 2.527 ± 0.322
1.982IleGlu: 1.982 ± 0.207
1.288IlePhe: 1.288 ± 0.186
2.18IleGly: 2.18 ± 0.217
0.57IleHis: 0.57 ± 0.126
1.288IleIle: 1.288 ± 0.215
1.288IleLys: 1.288 ± 0.209
3.865IleLeu: 3.865 ± 0.305
1.239IleMet: 1.239 ± 0.19
1.115IleAsn: 1.115 ± 0.16
1.808IlePro: 1.808 ± 0.197
1.065IleGln: 1.065 ± 0.175
2.477IleArg: 2.477 ± 0.234
2.75IleSer: 2.75 ± 0.298
2.007IleThr: 2.007 ± 0.236
2.75IleVal: 2.75 ± 0.241
0.223IleTrp: 0.223 ± 0.077
1.561IleTyr: 1.561 ± 0.208
0.0IleXaa: 0.0 ± 0.0
Lys
3.221LysAla: 3.221 ± 0.374
0.57LysCys: 0.57 ± 0.116
1.957LysAsp: 1.957 ± 0.175
1.288LysGlu: 1.288 ± 0.159
1.437LysPhe: 1.437 ± 0.183
1.288LysGly: 1.288 ± 0.185
1.065LysHis: 1.065 ± 0.158
1.808LysIle: 1.808 ± 0.229
1.858LysLys: 1.858 ± 0.276
3.32LysLeu: 3.32 ± 0.415
1.016LysMet: 1.016 ± 0.175
1.536LysAsn: 1.536 ± 0.185
2.254LysPro: 2.254 ± 0.258
1.214LysGln: 1.214 ± 0.174
2.576LysArg: 2.576 ± 0.295
2.502LysSer: 2.502 ± 0.277
2.378LysThr: 2.378 ± 0.244
2.106LysVal: 2.106 ± 0.261
0.545LysTrp: 0.545 ± 0.111
1.239LysTyr: 1.239 ± 0.157
0.0LysXaa: 0.0 ± 0.0
Leu
10.405LeuAla: 10.405 ± 0.505
2.131LeuCys: 2.131 ± 0.261
4.633LeuAsp: 4.633 ± 0.357
4.955LeuGlu: 4.955 ± 0.56
3.939LeuPhe: 3.939 ± 0.336
6.193LeuGly: 6.193 ± 0.363
1.734LeuHis: 1.734 ± 0.205
3.32LeuIle: 3.32 ± 0.307
3.493LeuLys: 3.493 ± 0.348
9.364LeuLeu: 9.364 ± 0.524
1.957LeuMet: 1.957 ± 0.254
2.824LeuAsn: 2.824 ± 0.265
4.905LeuPro: 4.905 ± 0.403
2.329LeuGln: 2.329 ± 0.221
7.705LeuArg: 7.705 ± 0.483
6.367LeuSer: 6.367 ± 0.335
5.054LeuThr: 5.054 ± 0.374
5.847LeuVal: 5.847 ± 0.381
1.189LeuTrp: 1.189 ± 0.155
2.502LeuTyr: 2.502 ± 0.305
0.0LeuXaa: 0.0 ± 0.0
Met
2.775MetAla: 2.775 ± 0.223
0.52MetCys: 0.52 ± 0.119
1.189MetAsp: 1.189 ± 0.155
1.214MetGlu: 1.214 ± 0.164
1.04MetPhe: 1.04 ± 0.156
1.709MetGly: 1.709 ± 0.235
0.694MetHis: 0.694 ± 0.125
0.966MetIle: 0.966 ± 0.147
0.644MetLys: 0.644 ± 0.134
2.329MetLeu: 2.329 ± 0.225
0.57MetMet: 0.57 ± 0.116
0.793MetAsn: 0.793 ± 0.146
1.486MetPro: 1.486 ± 0.242
0.669MetGln: 0.669 ± 0.149
1.709MetArg: 1.709 ± 0.218
1.412MetSer: 1.412 ± 0.165
1.313MetThr: 1.313 ± 0.21
1.387MetVal: 1.387 ± 0.212
0.248MetTrp: 0.248 ± 0.067
0.892MetTyr: 0.892 ± 0.161
0.0MetXaa: 0.0 ± 0.0
Asn
2.824AsnAla: 2.824 ± 0.304
0.694AsnCys: 0.694 ± 0.135
1.536AsnAsp: 1.536 ± 0.194
1.685AsnGlu: 1.685 ± 0.245
1.263AsnPhe: 1.263 ± 0.204
2.23AsnGly: 2.23 ± 0.237
0.396AsnHis: 0.396 ± 0.097
1.313AsnIle: 1.313 ± 0.174
1.338AsnLys: 1.338 ± 0.198
2.527AsnLeu: 2.527 ± 0.245
0.718AsnMet: 0.718 ± 0.13
1.09AsnAsn: 1.09 ± 0.145
1.363AsnPro: 1.363 ± 0.172
0.57AsnGln: 0.57 ± 0.117
1.982AsnArg: 1.982 ± 0.201
2.279AsnSer: 2.279 ± 0.268
1.858AsnThr: 1.858 ± 0.193
2.18AsnVal: 2.18 ± 0.193
0.396AsnTrp: 0.396 ± 0.093
0.941AsnTyr: 0.941 ± 0.15
0.0AsnXaa: 0.0 ± 0.0
Pro
6.54ProAla: 6.54 ± 0.374
1.313ProCys: 1.313 ± 0.223
2.973ProAsp: 2.973 ± 0.271
3.32ProGlu: 3.32 ± 0.304
1.61ProPhe: 1.61 ± 0.19
4.707ProGly: 4.707 ± 0.431
1.387ProHis: 1.387 ± 0.239
2.031ProIle: 2.031 ± 0.273
1.784ProLys: 1.784 ± 0.226
4.41ProLeu: 4.41 ± 0.398
1.115ProMet: 1.115 ± 0.175
1.164ProAsn: 1.164 ± 0.146
5.723ProPro: 5.723 ± 0.617
2.254ProGln: 2.254 ± 0.302
4.657ProArg: 4.657 ± 0.567
5.301ProSer: 5.301 ± 0.844
3.518ProThr: 3.518 ± 0.398
4.038ProVal: 4.038 ± 0.259
0.57ProTrp: 0.57 ± 0.132
1.239ProTyr: 1.239 ± 0.143
0.0ProXaa: 0.0 ± 0.0
Gln
2.7GlnAla: 2.7 ± 0.35
0.52GlnCys: 0.52 ± 0.103
1.189GlnAsp: 1.189 ± 0.178
1.288GlnGlu: 1.288 ± 0.179
0.941GlnPhe: 0.941 ± 0.139
1.189GlnGly: 1.189 ± 0.149
0.917GlnHis: 0.917 ± 0.18
1.313GlnIle: 1.313 ± 0.203
1.04GlnLys: 1.04 ± 0.149
2.527GlnLeu: 2.527 ± 0.189
0.446GlnMet: 0.446 ± 0.09
0.892GlnAsn: 0.892 ± 0.161
2.056GlnPro: 2.056 ± 0.28
1.61GlnGln: 1.61 ± 0.321
2.477GlnArg: 2.477 ± 0.264
2.056GlnSer: 2.056 ± 0.213
1.709GlnThr: 1.709 ± 0.283
1.486GlnVal: 1.486 ± 0.214
0.396GlnTrp: 0.396 ± 0.089
0.743GlnTyr: 0.743 ± 0.121
0.0GlnXaa: 0.0 ± 0.0
Arg
8.126ArgAla: 8.126 ± 0.595
1.288ArgCys: 1.288 ± 0.203
4.286ArgAsp: 4.286 ± 0.431
4.732ArgGlu: 4.732 ± 0.377
2.626ArgPhe: 2.626 ± 0.293
6.243ArgGly: 6.243 ± 0.43
1.462ArgHis: 1.462 ± 0.156
2.75ArgIle: 2.75 ± 0.255
2.626ArgLys: 2.626 ± 0.3
6.243ArgLeu: 6.243 ± 0.394
1.462ArgMet: 1.462 ± 0.19
2.403ArgAsn: 2.403 ± 0.243
4.088ArgPro: 4.088 ± 0.513
2.403ArgGln: 2.403 ± 0.298
8.596ArgArg: 8.596 ± 0.92
5.45ArgSer: 5.45 ± 0.405
3.344ArgThr: 3.344 ± 0.292
5.425ArgVal: 5.425 ± 0.457
0.768ArgTrp: 0.768 ± 0.145
1.883ArgTyr: 1.883 ± 0.243
0.0ArgXaa: 0.0 ± 0.0
Ser
9.785SerAla: 9.785 ± 0.532
1.734SerCys: 1.734 ± 0.173
3.84SerAsp: 3.84 ± 0.323
4.088SerGlu: 4.088 ± 0.286
2.651SerPhe: 2.651 ± 0.274
5.946SerGly: 5.946 ± 0.384
1.387SerHis: 1.387 ± 0.15
2.106SerIle: 2.106 ± 0.231
1.808SerLys: 1.808 ± 0.204
6.515SerLeu: 6.515 ± 0.363
1.561SerMet: 1.561 ± 0.188
1.808SerAsn: 1.808 ± 0.202
5.153SerPro: 5.153 ± 0.661
1.982SerGln: 1.982 ± 0.239
5.871SerArg: 5.871 ± 0.504
7.68SerSer: 7.68 ± 0.948
3.889SerThr: 3.889 ± 0.45
5.301SerVal: 5.301 ± 0.347
0.941SerTrp: 0.941 ± 0.194
1.734SerTyr: 1.734 ± 0.187
0.0SerXaa: 0.0 ± 0.0
Thr
6.59ThrAla: 6.59 ± 0.533
1.288ThrCys: 1.288 ± 0.232
2.898ThrAsp: 2.898 ± 0.252
3.32ThrGlu: 3.32 ± 0.267
2.131ThrPhe: 2.131 ± 0.258
3.468ThrGly: 3.468 ± 0.266
0.991ThrHis: 0.991 ± 0.142
2.155ThrIle: 2.155 ± 0.23
1.784ThrLys: 1.784 ± 0.192
5.376ThrLeu: 5.376 ± 0.382
1.387ThrMet: 1.387 ± 0.195
1.462ThrAsn: 1.462 ± 0.196
2.973ThrPro: 2.973 ± 0.347
1.338ThrGln: 1.338 ± 0.179
4.36ThrArg: 4.36 ± 0.366
4.484ThrSer: 4.484 ± 0.348
4.112ThrThr: 4.112 ± 0.79
4.187ThrVal: 4.187 ± 0.395
0.694ThrTrp: 0.694 ± 0.118
1.387ThrTyr: 1.387 ± 0.172
0.0ThrXaa: 0.0 ± 0.0
Val
8.027ValAla: 8.027 ± 0.458
1.412ValCys: 1.412 ± 0.221
3.295ValAsp: 3.295 ± 0.263
3.84ValGlu: 3.84 ± 0.337
3.221ValPhe: 3.221 ± 0.346
3.815ValGly: 3.815 ± 0.295
1.065ValHis: 1.065 ± 0.151
2.874ValIle: 2.874 ± 0.289
1.908ValLys: 1.908 ± 0.254
5.772ValLeu: 5.772 ± 0.422
2.106ValMet: 2.106 ± 0.22
2.205ValAsn: 2.205 ± 0.281
3.964ValPro: 3.964 ± 0.334
1.709ValGln: 1.709 ± 0.224
4.286ValArg: 4.286 ± 0.304
5.401ValSer: 5.401 ± 0.356
4.633ValThr: 4.633 ± 0.469
5.202ValVal: 5.202 ± 0.422
0.718ValTrp: 0.718 ± 0.14
2.155ValTyr: 2.155 ± 0.253
0.0ValXaa: 0.0 ± 0.0
Trp
0.768TrpAla: 0.768 ± 0.144
0.223TrpCys: 0.223 ± 0.075
0.669TrpAsp: 0.669 ± 0.144
0.446TrpGlu: 0.446 ± 0.103
0.372TrpPhe: 0.372 ± 0.089
0.818TrpGly: 0.818 ± 0.141
0.446TrpHis: 0.446 ± 0.101
0.297TrpIle: 0.297 ± 0.065
0.446TrpLys: 0.446 ± 0.093
1.536TrpLeu: 1.536 ± 0.195
0.347TrpMet: 0.347 ± 0.083
0.248TrpAsn: 0.248 ± 0.066
0.867TrpPro: 0.867 ± 0.122
0.297TrpGln: 0.297 ± 0.083
1.189TrpArg: 1.189 ± 0.217
0.892TrpSer: 0.892 ± 0.155
0.669TrpThr: 0.669 ± 0.119
0.545TrpVal: 0.545 ± 0.1
0.173TrpTrp: 0.173 ± 0.06
0.223TrpTyr: 0.223 ± 0.071
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.295TyrAla: 3.295 ± 0.259
0.669TyrCys: 0.669 ± 0.123
1.635TyrAsp: 1.635 ± 0.197
1.635TyrGlu: 1.635 ± 0.231
1.016TyrPhe: 1.016 ± 0.171
2.081TyrGly: 2.081 ± 0.164
0.446TyrHis: 0.446 ± 0.099
0.991TyrIle: 0.991 ± 0.173
0.917TyrLys: 0.917 ± 0.152
2.948TyrLeu: 2.948 ± 0.335
0.793TyrMet: 0.793 ± 0.133
0.941TyrAsn: 0.941 ± 0.174
1.363TyrPro: 1.363 ± 0.176
0.372TyrGln: 0.372 ± 0.074
1.585TyrArg: 1.585 ± 0.213
2.131TyrSer: 2.131 ± 0.199
1.437TyrThr: 1.437 ± 0.21
2.279TyrVal: 2.279 ± 0.208
0.396TyrTrp: 0.396 ± 0.089
1.164TyrTyr: 1.164 ± 0.205
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 72 proteins (40367 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski