Amino acid dipepetide frequency for Ceratocystis fimbriata f. sp. platani

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.067AlaAla: 11.067 ± 0.147	0.935AlaCys: 0.935 ± 0.023	4.792AlaAsp: 4.792 ± 0.048	5.978AlaGlu: 5.978 ± 0.116	3.043AlaPhe: 3.043 ± 0.035	5.738AlaGly: 5.738 ± 0.058	1.788AlaHis: 1.788 ± 0.024	4.446AlaIle: 4.446 ± 0.043	4.781AlaLys: 4.781 ± 0.057	7.907AlaLeu: 7.907 ± 0.067	2.486AlaMet: 2.486 ± 0.033	3.318AlaAsn: 3.318 ± 0.033	5.217AlaPro: 5.217 ± 0.066	3.793AlaGln: 3.793 ± 0.06	5.001AlaArg: 5.001 ± 0.054	8.114AlaSer: 8.114 ± 0.073	6.178AlaThr: 6.178 ± 0.058	5.729AlaVal: 5.729 ± 0.056	1.015AlaTrp: 1.015 ± 0.019	2.115AlaTyr: 2.115 ± 0.036	0.001AlaXaa: 0.001 ± 0.001
Cys	0.769CysAla: 0.769 ± 0.017	0.173CysCys: 0.173 ± 0.009	0.617CysAsp: 0.617 ± 0.014	0.565CysGlu: 0.565 ± 0.015	0.478CysPhe: 0.478 ± 0.014	0.812CysGly: 0.812 ± 0.02	0.288CysHis: 0.288 ± 0.011	0.599CysIle: 0.599 ± 0.016	0.489CysLys: 0.489 ± 0.015	1.044CysLeu: 1.044 ± 0.023	0.278CysMet: 0.278 ± 0.01	0.405CysAsn: 0.405 ± 0.011	0.522CysPro: 0.522 ± 0.014	0.383CysGln: 0.383 ± 0.013	0.595CysArg: 0.595 ± 0.015	0.781CysSer: 0.781 ± 0.019	0.609CysThr: 0.609 ± 0.017	0.665CysVal: 0.665 ± 0.016	0.155CysTrp: 0.155 ± 0.008	0.305CysTyr: 0.305 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	5.133AspAla: 5.133 ± 0.048	0.604AspCys: 0.604 ± 0.015	5.054AspAsp: 5.054 ± 0.067	5.004AspGlu: 5.004 ± 0.063	2.316AspPhe: 2.316 ± 0.033	4.069AspGly: 4.069 ± 0.042	1.192AspHis: 1.192 ± 0.021	3.288AspIle: 3.288 ± 0.034	2.789AspLys: 2.789 ± 0.036	5.061AspLeu: 5.061 ± 0.046	1.592AspMet: 1.592 ± 0.024	2.131AspAsn: 2.131 ± 0.029	3.148AspPro: 3.148 ± 0.034	1.851AspGln: 1.851 ± 0.025	2.939AspArg: 2.939 ± 0.038	4.617AspSer: 4.617 ± 0.047	3.017AspThr: 3.017 ± 0.038	3.871AspVal: 3.871 ± 0.044	0.804AspTrp: 0.804 ± 0.019	1.65AspTyr: 1.65 ± 0.029	0.0AspXaa: 0.0 ± 0.0
Glu	6.431GluAla: 6.431 ± 0.106	0.561GluCys: 0.561 ± 0.015	4.586GluAsp: 4.586 ± 0.055	5.646GluGlu: 5.646 ± 0.101	2.052GluPhe: 2.052 ± 0.031	3.439GluGly: 3.439 ± 0.039	1.277GluHis: 1.277 ± 0.021	3.285GluIle: 3.285 ± 0.039	4.02GluLys: 4.02 ± 0.056	5.265GluLeu: 5.265 ± 0.063	1.684GluMet: 1.684 ± 0.028	2.528GluAsn: 2.528 ± 0.032	2.761GluPro: 2.761 ± 0.072	2.393GluGln: 2.393 ± 0.036	3.751GluArg: 3.751 ± 0.055	4.416GluSer: 4.416 ± 0.052	3.701GluThr: 3.701 ± 0.046	3.579GluVal: 3.579 ± 0.035	0.879GluTrp: 0.879 ± 0.018	1.67GluTyr: 1.67 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	2.939PheAla: 2.939 ± 0.034	0.49PheCys: 0.49 ± 0.014	2.297PheAsp: 2.297 ± 0.034	2.146PheGlu: 2.146 ± 0.03	1.519PhePhe: 1.519 ± 0.028	2.627PheGly: 2.627 ± 0.037	0.823PheHis: 0.823 ± 0.017	1.687PheIle: 1.687 ± 0.028	1.619PheLys: 1.619 ± 0.031	3.104PheLeu: 3.104 ± 0.038	0.853PheMet: 0.853 ± 0.016	1.461PheAsn: 1.461 ± 0.026	1.688PhePro: 1.688 ± 0.029	1.278PheGln: 1.278 ± 0.024	1.854PheArg: 1.854 ± 0.027	2.979PheSer: 2.979 ± 0.036	2.021PheThr: 2.021 ± 0.029	2.336PheVal: 2.336 ± 0.034	0.517PheTrp: 0.517 ± 0.015	1.042PheTyr: 1.042 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.333GlyAla: 5.333 ± 0.055	0.689GlyCys: 0.689 ± 0.015	3.677GlyAsp: 3.677 ± 0.037	3.382GlyGlu: 3.382 ± 0.04	2.578GlyPhe: 2.578 ± 0.036	5.544GlyGly: 5.544 ± 0.087	1.63GlyHis: 1.63 ± 0.028	3.379GlyIle: 3.379 ± 0.034	3.375GlyLys: 3.375 ± 0.04	5.68GlyLeu: 5.68 ± 0.049	1.653GlyMet: 1.653 ± 0.03	2.522GlyAsn: 2.522 ± 0.031	3.132GlyPro: 3.132 ± 0.04	2.368GlyGln: 2.368 ± 0.034	3.731GlyArg: 3.731 ± 0.05	5.83GlySer: 5.83 ± 0.057	3.705GlyThr: 3.705 ± 0.05	4.104GlyVal: 4.104 ± 0.047	0.979GlyTrp: 0.979 ± 0.02	1.92GlyTyr: 1.92 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	1.764HisAla: 1.764 ± 0.026	0.265HisCys: 0.265 ± 0.011	1.347HisAsp: 1.347 ± 0.027	1.295HisGlu: 1.295 ± 0.02	0.826HisPhe: 0.826 ± 0.018	1.594HisGly: 1.594 ± 0.025	0.799HisHis: 0.799 ± 0.021	1.209HisIle: 1.209 ± 0.021	0.992HisLys: 0.992 ± 0.02	1.958HisLeu: 1.958 ± 0.026	0.634HisMet: 0.634 ± 0.016	0.926HisAsn: 0.926 ± 0.018	1.383HisPro: 1.383 ± 0.026	1.059HisGln: 1.059 ± 0.03	1.399HisArg: 1.399 ± 0.027	1.781HisSer: 1.781 ± 0.031	1.229HisThr: 1.229 ± 0.024	1.417HisVal: 1.417 ± 0.026	0.263HisTrp: 0.263 ± 0.009	0.674HisTyr: 0.674 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.322IleAla: 4.322 ± 0.036	0.626IleCys: 0.626 ± 0.016	3.252IleAsp: 3.252 ± 0.035	3.16IleGlu: 3.16 ± 0.032	1.849IlePhe: 1.849 ± 0.027	2.969IleGly: 2.969 ± 0.036	1.138IleHis: 1.138 ± 0.02	2.49IleIle: 2.49 ± 0.036	2.538IleLys: 2.538 ± 0.03	4.265IleLeu: 4.265 ± 0.045	1.199IleMet: 1.199 ± 0.021	1.957IleAsn: 1.957 ± 0.027	2.863IlePro: 2.863 ± 0.034	1.788IleGln: 1.788 ± 0.026	2.794IleArg: 2.794 ± 0.03	4.051IleSer: 4.051 ± 0.04	2.805IleThr: 2.805 ± 0.031	3.172IleVal: 3.172 ± 0.038	0.645IleTrp: 0.645 ± 0.017	1.303IleTyr: 1.303 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	5.216LysAla: 5.216 ± 0.054	0.456LysCys: 0.456 ± 0.013	2.949LysAsp: 2.949 ± 0.039	3.482LysGlu: 3.482 ± 0.052	1.545LysPhe: 1.545 ± 0.03	2.899LysGly: 2.899 ± 0.036	1.116LysHis: 1.116 ± 0.02	2.618LysIle: 2.618 ± 0.034	3.998LysLys: 3.998 ± 0.069	4.387LysLeu: 4.387 ± 0.045	1.262LysMet: 1.262 ± 0.019	2.029LysAsn: 2.029 ± 0.027	2.898LysPro: 2.898 ± 0.038	1.923LysGln: 1.923 ± 0.03	3.415LysArg: 3.415 ± 0.048	3.659LysSer: 3.659 ± 0.04	3.322LysThr: 3.322 ± 0.038	2.955LysVal: 2.955 ± 0.036	0.678LysTrp: 0.678 ± 0.018	1.417LysTyr: 1.417 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	8.145LeuAla: 8.145 ± 0.067	1.055LeuCys: 1.055 ± 0.019	5.267LeuAsp: 5.267 ± 0.042	5.61LeuGlu: 5.61 ± 0.057	2.969LeuPhe: 2.969 ± 0.037	5.422LeuGly: 5.422 ± 0.046	1.998LeuHis: 1.998 ± 0.031	3.684LeuIle: 3.684 ± 0.039	4.395LeuLys: 4.395 ± 0.052	7.531LeuLeu: 7.531 ± 0.074	1.984LeuMet: 1.984 ± 0.03	3.171LeuAsn: 3.171 ± 0.035	4.888LeuPro: 4.888 ± 0.055	3.671LeuGln: 3.671 ± 0.049	5.55LeuArg: 5.55 ± 0.057	6.822LeuSer: 6.822 ± 0.065	4.477LeuThr: 4.477 ± 0.043	5.337LeuVal: 5.337 ± 0.048	1.061LeuTrp: 1.061 ± 0.021	2.196LeuTyr: 2.196 ± 0.031	0.0LeuXaa: 0.0 ± 0.0
Met	2.722MetAla: 2.722 ± 0.03	0.254MetCys: 0.254 ± 0.01	1.495MetAsp: 1.495 ± 0.024	1.512MetGlu: 1.512 ± 0.024	0.869MetPhe: 0.869 ± 0.02	1.679MetGly: 1.679 ± 0.028	0.55MetHis: 0.55 ± 0.014	1.069MetIle: 1.069 ± 0.022	1.132MetLys: 1.132 ± 0.019	2.1MetLeu: 2.1 ± 0.03	0.709MetMet: 0.709 ± 0.019	0.922MetAsn: 0.922 ± 0.018	1.452MetPro: 1.452 ± 0.027	0.999MetGln: 0.999 ± 0.023	1.459MetArg: 1.459 ± 0.023	2.118MetSer: 2.118 ± 0.029	1.514MetThr: 1.514 ± 0.024	1.491MetVal: 1.491 ± 0.025	0.275MetTrp: 0.275 ± 0.008	0.619MetTyr: 0.619 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.293AsnAla: 3.293 ± 0.037	0.411AsnCys: 0.411 ± 0.013	2.267AsnAsp: 2.267 ± 0.03	2.205AsnGlu: 2.205 ± 0.034	1.378AsnPhe: 1.378 ± 0.026	2.931AsnGly: 2.931 ± 0.037	0.857AsnHis: 0.857 ± 0.018	2.175AsnIle: 2.175 ± 0.028	1.846AsnLys: 1.846 ± 0.026	3.149AsnLeu: 3.149 ± 0.036	1.044AsnMet: 1.044 ± 0.022	1.81AsnAsn: 1.81 ± 0.041	2.373AsnPro: 2.373 ± 0.033	1.317AsnGln: 1.317 ± 0.024	1.946AsnArg: 1.946 ± 0.029	3.124AsnSer: 3.124 ± 0.038	2.38AsnThr: 2.38 ± 0.034	2.342AsnVal: 2.342 ± 0.034	0.529AsnTrp: 0.529 ± 0.015	1.099AsnTyr: 1.099 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	5.524ProAla: 5.524 ± 0.065	0.433ProCys: 0.433 ± 0.015	3.088ProAsp: 3.088 ± 0.034	3.831ProGlu: 3.831 ± 0.048	1.768ProPhe: 1.768 ± 0.028	3.634ProGly: 3.634 ± 0.04	1.25ProHis: 1.25 ± 0.023	2.532ProIle: 2.532 ± 0.033	2.683ProLys: 2.683 ± 0.036	4.308ProLeu: 4.308 ± 0.049	1.26ProMet: 1.26 ± 0.024	2.063ProAsn: 2.063 ± 0.03	4.511ProPro: 4.511 ± 0.082	2.302ProGln: 2.302 ± 0.045	2.918ProArg: 2.918 ± 0.038	5.532ProSer: 5.532 ± 0.073	3.93ProThr: 3.93 ± 0.047	3.566ProVal: 3.566 ± 0.04	0.583ProTrp: 0.583 ± 0.013	1.316ProTyr: 1.316 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.906GlnAla: 3.906 ± 0.056	0.389GlnCys: 0.389 ± 0.011	2.024GlnAsp: 2.024 ± 0.031	2.337GlnGlu: 2.337 ± 0.037	1.217GlnPhe: 1.217 ± 0.023	2.126GlnGly: 2.126 ± 0.029	1.094GlnHis: 1.094 ± 0.03	1.922GlnIle: 1.922 ± 0.027	2.072GlnLys: 2.072 ± 0.03	3.381GlnLeu: 3.381 ± 0.044	1.011GlnMet: 1.011 ± 0.025	1.587GlnAsn: 1.587 ± 0.029	2.357GlnPro: 2.357 ± 0.038	3.231GlnGln: 3.231 ± 0.134	2.571GlnArg: 2.571 ± 0.035	2.877GlnSer: 2.877 ± 0.035	2.314GlnThr: 2.314 ± 0.032	2.121GlnVal: 2.121 ± 0.026	0.486GlnTrp: 0.486 ± 0.013	1.11GlnTyr: 1.11 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	4.714ArgAla: 4.714 ± 0.048	0.584ArgCys: 0.584 ± 0.016	3.393ArgAsp: 3.393 ± 0.047	3.739ArgGlu: 3.739 ± 0.047	2.091ArgPhe: 2.091 ± 0.034	3.431ArgGly: 3.431 ± 0.043	1.442ArgHis: 1.442 ± 0.025	2.907ArgIle: 2.907 ± 0.033	3.509ArgLys: 3.509 ± 0.044	5.23ArgLeu: 5.23 ± 0.054	1.466ArgMet: 1.466 ± 0.021	2.352ArgAsn: 2.352 ± 0.03	3.015ArgPro: 3.015 ± 0.044	2.478ArgGln: 2.478 ± 0.034	4.544ArgArg: 4.544 ± 0.061	4.309ArgSer: 4.309 ± 0.045	3.064ArgThr: 3.064 ± 0.033	3.23ArgVal: 3.23 ± 0.04	0.761ArgTrp: 0.761 ± 0.017	1.562ArgTyr: 1.562 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	7.399SerAla: 7.399 ± 0.067	0.728SerCys: 0.728 ± 0.017	4.574SerAsp: 4.574 ± 0.05	4.396SerGlu: 4.396 ± 0.05	2.889SerPhe: 2.889 ± 0.035	5.859SerGly: 5.859 ± 0.061	1.951SerHis: 1.951 ± 0.032	3.908SerIle: 3.908 ± 0.041	4.036SerLys: 4.036 ± 0.045	6.966SerLeu: 6.966 ± 0.064	1.942SerMet: 1.942 ± 0.029	3.18SerAsn: 3.18 ± 0.038	5.038SerPro: 5.038 ± 0.072	3.315SerGln: 3.315 ± 0.041	4.685SerArg: 4.685 ± 0.049	9.159SerSer: 9.159 ± 0.108	5.603SerThr: 5.603 ± 0.06	4.704SerVal: 4.704 ± 0.045	0.948SerTrp: 0.948 ± 0.02	1.963SerTyr: 1.963 ± 0.029	0.001SerXaa: 0.001 ± 0.001
Thr	5.889ThrAla: 5.889 ± 0.057	0.633ThrCys: 0.633 ± 0.018	3.016ThrAsp: 3.016 ± 0.03	3.379ThrGlu: 3.379 ± 0.044	1.958ThrPhe: 1.958 ± 0.029	4.136ThrGly: 4.136 ± 0.045	1.291ThrHis: 1.291 ± 0.018	3.046ThrIle: 3.046 ± 0.036	2.91ThrLys: 2.91 ± 0.038	5.023ThrLeu: 5.023 ± 0.049	1.341ThrMet: 1.341 ± 0.021	2.157ThrAsn: 2.157 ± 0.034	4.377ThrPro: 4.377 ± 0.047	2.139ThrGln: 2.139 ± 0.034	3.045ThrArg: 3.045 ± 0.035	5.428ThrSer: 5.428 ± 0.052	4.478ThrThr: 4.478 ± 0.058	3.738ThrVal: 3.738 ± 0.054	0.709ThrTrp: 0.709 ± 0.018	1.463ThrTyr: 1.463 ± 0.026	0.001ThrXaa: 0.001 ± 0.001
Val	5.709ValAla: 5.709 ± 0.048	0.743ValCys: 0.743 ± 0.016	3.794ValAsp: 3.794 ± 0.04	3.892ValGlu: 3.892 ± 0.057	2.418ValPhe: 2.418 ± 0.033	3.584ValGly: 3.584 ± 0.048	1.333ValHis: 1.333 ± 0.023	2.93ValIle: 2.93 ± 0.035	3.084ValLys: 3.084 ± 0.037	5.408ValLeu: 5.408 ± 0.052	1.494ValMet: 1.494 ± 0.022	2.228ValAsn: 2.228 ± 0.029	3.662ValPro: 3.662 ± 0.043	2.343ValGln: 2.343 ± 0.03	3.37ValArg: 3.37 ± 0.036	4.792ValSer: 4.792 ± 0.05	3.522ValThr: 3.522 ± 0.052	4.417ValVal: 4.417 ± 0.052	0.771ValTrp: 0.771 ± 0.019	1.688ValTyr: 1.688 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.057TrpAla: 1.057 ± 0.021	0.157TrpCys: 0.157 ± 0.008	0.911TrpAsp: 0.911 ± 0.024	0.805TrpGlu: 0.805 ± 0.017	0.454TrpPhe: 0.454 ± 0.012	0.765TrpGly: 0.765 ± 0.018	0.292TrpHis: 0.292 ± 0.011	0.684TrpIle: 0.684 ± 0.018	0.774TrpLys: 0.774 ± 0.017	1.096TrpLeu: 1.096 ± 0.023	0.376TrpMet: 0.376 ± 0.012	0.558TrpAsn: 0.558 ± 0.012	0.486TrpPro: 0.486 ± 0.012	0.471TrpGln: 0.471 ± 0.013	0.755TrpArg: 0.755 ± 0.018	0.883TrpSer: 0.883 ± 0.018	0.768TrpThr: 0.768 ± 0.018	0.78TrpVal: 0.78 ± 0.017	0.23TrpTrp: 0.23 ± 0.009	0.362TrpTyr: 0.362 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.108TyrAla: 2.108 ± 0.029	0.345TyrCys: 0.345 ± 0.012	1.728TyrAsp: 1.728 ± 0.027	1.558TyrGlu: 1.558 ± 0.027	1.066TyrPhe: 1.066 ± 0.021	1.953TyrGly: 1.953 ± 0.029	0.703TyrHis: 0.703 ± 0.017	1.329TyrIle: 1.329 ± 0.025	1.183TyrLys: 1.183 ± 0.023	2.37TyrLeu: 2.37 ± 0.033	0.672TyrMet: 0.672 ± 0.014	1.171TyrAsn: 1.171 ± 0.023	1.263TyrPro: 1.263 ± 0.024	1.031TyrGln: 1.031 ± 0.022	1.499TyrArg: 1.499 ± 0.024	1.973TyrSer: 1.973 ± 0.031	1.519TyrThr: 1.519 ± 0.026	1.63TyrVal: 1.63 ± 0.021	0.375TyrTrp: 0.375 ± 0.012	0.898TyrTyr: 0.898 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5620 proteins (2778377 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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