Amino acid dipepetide frequency for Desulfocurvibacter africanus subsp. africanus str. Walvis Bay

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.717AlaAla: 11.717 ± 0.125	1.533AlaCys: 1.533 ± 0.04	5.121AlaAsp: 5.121 ± 0.072	7.305AlaGlu: 7.305 ± 0.094	3.86AlaPhe: 3.86 ± 0.059	9.266AlaGly: 9.266 ± 0.091	1.937AlaHis: 1.937 ± 0.047	4.788AlaIle: 4.788 ± 0.067	4.379AlaLys: 4.379 ± 0.068	12.137AlaLeu: 12.137 ± 0.112	3.528AlaMet: 3.528 ± 0.064	2.43AlaAsn: 2.43 ± 0.046	4.157AlaPro: 4.157 ± 0.065	3.888AlaGln: 3.888 ± 0.064	7.245AlaArg: 7.245 ± 0.091	5.796AlaSer: 5.796 ± 0.074	4.527AlaThr: 4.527 ± 0.063	7.872AlaVal: 7.872 ± 0.08	1.476AlaTrp: 1.476 ± 0.043	2.555AlaTyr: 2.555 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	1.249CysAla: 1.249 ± 0.032	0.237CysCys: 0.237 ± 0.017	0.571CysAsp: 0.571 ± 0.023	0.585CysGlu: 0.585 ± 0.022	0.427CysPhe: 0.427 ± 0.018	1.333CysGly: 1.333 ± 0.037	0.383CysHis: 0.383 ± 0.025	0.567CysIle: 0.567 ± 0.023	0.432CysLys: 0.432 ± 0.021	1.398CysLeu: 1.398 ± 0.038	0.327CysMet: 0.327 ± 0.016	0.291CysAsn: 0.291 ± 0.016	0.835CysPro: 0.835 ± 0.032	0.383CysGln: 0.383 ± 0.021	0.964CysArg: 0.964 ± 0.027	0.726CysSer: 0.726 ± 0.027	0.525CysThr: 0.525 ± 0.023	0.85CysVal: 0.85 ± 0.03	0.141CysTrp: 0.141 ± 0.011	0.304CysTyr: 0.304 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.875AspAla: 4.875 ± 0.064	0.64AspCys: 0.64 ± 0.026	2.367AspAsp: 2.367 ± 0.055	3.65AspGlu: 3.65 ± 0.054	2.283AspPhe: 2.283 ± 0.05	4.076AspGly: 4.076 ± 0.072	0.985AspHis: 0.985 ± 0.03	3.174AspIle: 3.174 ± 0.059	2.5AspLys: 2.5 ± 0.051	6.088AspLeu: 6.088 ± 0.071	1.687AspMet: 1.687 ± 0.038	1.395AspAsn: 1.395 ± 0.037	2.918AspPro: 2.918 ± 0.056	1.731AspGln: 1.731 ± 0.043	3.183AspArg: 3.183 ± 0.053	2.605AspSer: 2.605 ± 0.045	2.42AspThr: 2.42 ± 0.045	3.753AspVal: 3.753 ± 0.052	0.836AspTrp: 0.836 ± 0.024	1.569AspTyr: 1.569 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	7.336GluAla: 7.336 ± 0.091	0.67GluCys: 0.67 ± 0.024	3.235GluAsp: 3.235 ± 0.066	4.531GluGlu: 4.531 ± 0.073	2.326GluPhe: 2.326 ± 0.047	4.223GluGly: 4.223 ± 0.062	1.56GluHis: 1.56 ± 0.034	3.681GluIle: 3.681 ± 0.061	2.723GluLys: 2.723 ± 0.046	7.294GluLeu: 7.294 ± 0.086	1.661GluMet: 1.661 ± 0.035	1.811GluAsn: 1.811 ± 0.037	2.835GluPro: 2.835 ± 0.05	3.007GluGln: 3.007 ± 0.051	5.664GluArg: 5.664 ± 0.077	3.443GluSer: 3.443 ± 0.057	3.029GluThr: 3.029 ± 0.054	4.403GluVal: 4.403 ± 0.061	0.684GluTrp: 0.684 ± 0.028	1.618GluTyr: 1.618 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.539PheAla: 3.539 ± 0.059	0.574PheCys: 0.574 ± 0.026	2.151PheAsp: 2.151 ± 0.042	2.267PheGlu: 2.267 ± 0.046	1.735PhePhe: 1.735 ± 0.04	3.27PheGly: 3.27 ± 0.055	0.798PheHis: 0.798 ± 0.025	1.827PheIle: 1.827 ± 0.041	1.349PheLys: 1.349 ± 0.036	4.434PheLeu: 4.434 ± 0.067	0.988PheMet: 0.988 ± 0.028	1.024PheAsn: 1.024 ± 0.03	1.728PhePro: 1.728 ± 0.037	1.177PheGln: 1.177 ± 0.032	2.299PheArg: 2.299 ± 0.039	2.48PheSer: 2.48 ± 0.05	2.12PheThr: 2.12 ± 0.043	2.645PheVal: 2.645 ± 0.052	0.573PheTrp: 0.573 ± 0.025	1.098PheTyr: 1.098 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	6.888GlyAla: 6.888 ± 0.088	1.205GlyCys: 1.205 ± 0.034	3.812GlyAsp: 3.812 ± 0.062	4.937GlyGlu: 4.937 ± 0.069	3.459GlyPhe: 3.459 ± 0.054	6.505GlyGly: 6.505 ± 0.093	1.751GlyHis: 1.751 ± 0.038	4.204GlyIle: 4.204 ± 0.065	4.121GlyLys: 4.121 ± 0.057	10.172GlyLeu: 10.172 ± 0.115	2.569GlyMet: 2.569 ± 0.051	2.122GlyAsn: 2.122 ± 0.043	3.147GlyPro: 3.147 ± 0.062	3.435GlyGln: 3.435 ± 0.056	6.098GlyArg: 6.098 ± 0.072	4.58GlySer: 4.58 ± 0.072	3.693GlyThr: 3.693 ± 0.07	5.851GlyVal: 5.851 ± 0.082	1.178GlyTrp: 1.178 ± 0.035	2.284GlyTyr: 2.284 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	1.938HisAla: 1.938 ± 0.036	0.334HisCys: 0.334 ± 0.017	1.132HisAsp: 1.132 ± 0.032	1.35HisGlu: 1.35 ± 0.034	0.889HisPhe: 0.889 ± 0.03	1.972HisGly: 1.972 ± 0.046	0.499HisHis: 0.499 ± 0.022	1.05HisIle: 1.05 ± 0.03	0.824HisLys: 0.824 ± 0.024	2.093HisLeu: 2.093 ± 0.043	0.567HisMet: 0.567 ± 0.02	0.552HisAsn: 0.552 ± 0.022	1.24HisPro: 1.24 ± 0.033	0.561HisGln: 0.561 ± 0.021	1.177HisArg: 1.177 ± 0.031	1.04HisSer: 1.04 ± 0.031	0.866HisThr: 0.866 ± 0.028	1.45HisVal: 1.45 ± 0.036	0.264HisTrp: 0.264 ± 0.016	0.576HisTyr: 0.576 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	4.57IleAla: 4.57 ± 0.066	0.617IleCys: 0.617 ± 0.024	2.536IleAsp: 2.536 ± 0.047	3.116IleGlu: 3.116 ± 0.053	1.907IlePhe: 1.907 ± 0.043	3.864IleGly: 3.864 ± 0.054	0.965IleHis: 0.965 ± 0.027	2.579IleIle: 2.579 ± 0.052	2.059IleLys: 2.059 ± 0.049	5.389IleLeu: 5.389 ± 0.073	1.372IleMet: 1.372 ± 0.035	1.463IleAsn: 1.463 ± 0.038	2.525IlePro: 2.525 ± 0.044	1.478IleGln: 1.478 ± 0.035	3.169IleArg: 3.169 ± 0.056	2.979IleSer: 2.979 ± 0.06	2.547IleThr: 2.547 ± 0.049	3.638IleVal: 3.638 ± 0.058	0.568IleTrp: 0.568 ± 0.019	1.241IleTyr: 1.241 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	4.95LysAla: 4.95 ± 0.074	0.384LysCys: 0.384 ± 0.018	2.337LysAsp: 2.337 ± 0.044	2.551LysGlu: 2.551 ± 0.046	1.093LysPhe: 1.093 ± 0.03	3.167LysGly: 3.167 ± 0.054	0.779LysHis: 0.779 ± 0.025	2.002LysIle: 2.002 ± 0.047	1.792LysLys: 1.792 ± 0.046	4.079LysLeu: 4.079 ± 0.066	0.923LysMet: 0.923 ± 0.028	1.156LysAsn: 1.156 ± 0.032	2.441LysPro: 2.441 ± 0.049	1.416LysGln: 1.416 ± 0.035	2.814LysArg: 2.814 ± 0.045	2.231LysSer: 2.231 ± 0.042	2.115LysThr: 2.115 ± 0.041	2.837LysVal: 2.837 ± 0.05	0.394LysTrp: 0.394 ± 0.02	0.976LysTyr: 0.976 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	14.344LeuAla: 14.344 ± 0.147	1.348LeuCys: 1.348 ± 0.037	6.642LeuAsp: 6.642 ± 0.074	7.109LeuGlu: 7.109 ± 0.098	4.021LeuPhe: 4.021 ± 0.063	9.407LeuGly: 9.407 ± 0.116	2.226LeuHis: 2.226 ± 0.046	4.301LeuIle: 4.301 ± 0.06	4.225LeuLys: 4.225 ± 0.065	12.288LeuLeu: 12.288 ± 0.146	2.5LeuMet: 2.5 ± 0.05	2.815LeuAsn: 2.815 ± 0.051	5.802LeuPro: 5.802 ± 0.079	3.228LeuGln: 3.228 ± 0.056	8.252LeuArg: 8.252 ± 0.108	6.973LeuSer: 6.973 ± 0.088	5.818LeuThr: 5.818 ± 0.067	7.964LeuVal: 7.964 ± 0.093	1.191LeuTrp: 1.191 ± 0.038	2.322LeuTyr: 2.322 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	3.535MetAla: 3.535 ± 0.05	0.229MetCys: 0.229 ± 0.014	1.685MetAsp: 1.685 ± 0.046	1.7MetGlu: 1.7 ± 0.039	0.752MetPhe: 0.752 ± 0.026	2.126MetGly: 2.126 ± 0.045	0.611MetHis: 0.611 ± 0.025	1.08MetIle: 1.08 ± 0.033	0.953MetLys: 0.953 ± 0.031	2.929MetLeu: 2.929 ± 0.054	0.42MetMet: 0.42 ± 0.024	0.864MetAsn: 0.864 ± 0.029	1.604MetPro: 1.604 ± 0.037	0.925MetGln: 0.925 ± 0.028	2.082MetArg: 2.082 ± 0.042	1.746MetSer: 1.746 ± 0.034	1.451MetThr: 1.451 ± 0.037	1.792MetVal: 1.792 ± 0.04	0.177MetTrp: 0.177 ± 0.013	0.47MetTyr: 0.47 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.664AsnAla: 2.664 ± 0.048	0.359AsnCys: 0.359 ± 0.019	1.188AsnAsp: 1.188 ± 0.029	1.403AsnGlu: 1.403 ± 0.041	1.014AsnPhe: 1.014 ± 0.033	1.962AsnGly: 1.962 ± 0.051	0.474AsnHis: 0.474 ± 0.021	1.535AsnIle: 1.535 ± 0.04	1.028AsnLys: 1.028 ± 0.034	3.108AsnLeu: 3.108 ± 0.065	0.79AsnMet: 0.79 ± 0.026	0.686AsnAsn: 0.686 ± 0.027	1.809AsnPro: 1.809 ± 0.042	0.892AsnGln: 0.892 ± 0.027	1.711AsnArg: 1.711 ± 0.036	1.374AsnSer: 1.374 ± 0.036	1.236AsnThr: 1.236 ± 0.036	1.969AsnVal: 1.969 ± 0.041	0.361AsnTrp: 0.361 ± 0.018	0.763AsnTyr: 0.763 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	5.235ProAla: 5.235 ± 0.077	0.574ProCys: 0.574 ± 0.028	3.215ProAsp: 3.215 ± 0.056	4.426ProGlu: 4.426 ± 0.059	1.883ProPhe: 1.883 ± 0.038	4.619ProGly: 4.619 ± 0.069	0.924ProHis: 0.924 ± 0.029	1.896ProIle: 1.896 ± 0.044	1.886ProLys: 1.886 ± 0.043	4.947ProLeu: 4.947 ± 0.069	1.238ProMet: 1.238 ± 0.03	1.157ProAsn: 1.157 ± 0.035	2.112ProPro: 2.112 ± 0.051	1.691ProGln: 1.691 ± 0.044	2.754ProArg: 2.754 ± 0.053	2.643ProSer: 2.643 ± 0.049	2.1ProThr: 2.1 ± 0.043	3.716ProVal: 3.716 ± 0.063	0.744ProTrp: 0.744 ± 0.03	1.208ProTyr: 1.208 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	5.215GlnAla: 5.215 ± 0.075	0.34GlnCys: 0.34 ± 0.019	2.057GlnAsp: 2.057 ± 0.044	2.511GlnGlu: 2.511 ± 0.051	0.941GlnPhe: 0.941 ± 0.03	3.323GlnGly: 3.323 ± 0.061	0.611GlnHis: 0.611 ± 0.023	1.55GlnIle: 1.55 ± 0.04	1.303GlnLys: 1.303 ± 0.035	2.91GlnLeu: 2.91 ± 0.046	0.837GlnMet: 0.837 ± 0.029	0.946GlnAsn: 0.946 ± 0.032	1.763GlnPro: 1.763 ± 0.041	1.354GlnGln: 1.354 ± 0.041	2.344GlnArg: 2.344 ± 0.045	1.901GlnSer: 1.901 ± 0.046	1.735GlnThr: 1.735 ± 0.04	2.704GlnVal: 2.704 ± 0.052	0.356GlnTrp: 0.356 ± 0.019	0.662GlnTyr: 0.662 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	6.252ArgAla: 6.252 ± 0.084	0.741ArgCys: 0.741 ± 0.03	3.575ArgAsp: 3.575 ± 0.058	5.414ArgGlu: 5.414 ± 0.065	2.887ArgPhe: 2.887 ± 0.053	4.524ArgGly: 4.524 ± 0.06	1.584ArgHis: 1.584 ± 0.036	4.05ArgIle: 4.05 ± 0.06	3.299ArgLys: 3.299 ± 0.056	8.465ArgLeu: 8.465 ± 0.096	2.1ArgMet: 2.1 ± 0.045	1.96ArgAsn: 1.96 ± 0.043	3.211ArgPro: 3.211 ± 0.059	2.969ArgGln: 2.969 ± 0.055	5.221ArgArg: 5.221 ± 0.068	3.644ArgSer: 3.644 ± 0.055	3.21ArgThr: 3.21 ± 0.052	4.525ArgVal: 4.525 ± 0.066	0.794ArgTrp: 0.794 ± 0.025	1.77ArgTyr: 1.77 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.293SerAla: 5.293 ± 0.077	0.737SerCys: 0.737 ± 0.026	2.652SerAsp: 2.652 ± 0.048	3.531SerGlu: 3.531 ± 0.058	2.44SerPhe: 2.44 ± 0.046	5.573SerGly: 5.573 ± 0.088	1.11SerHis: 1.11 ± 0.029	2.856SerIle: 2.856 ± 0.051	2.115SerLys: 2.115 ± 0.048	6.584SerLeu: 6.584 ± 0.079	1.724SerMet: 1.724 ± 0.042	1.288SerAsn: 1.288 ± 0.035	2.833SerPro: 2.833 ± 0.051	1.963SerGln: 1.963 ± 0.043	3.964SerArg: 3.964 ± 0.062	3.241SerSer: 3.241 ± 0.065	2.614SerThr: 2.614 ± 0.054	4.096SerVal: 4.096 ± 0.063	0.744SerTrp: 0.744 ± 0.027	1.308SerTyr: 1.308 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	5.04ThrAla: 5.04 ± 0.07	0.558ThrCys: 0.558 ± 0.021	2.408ThrAsp: 2.408 ± 0.047	2.603ThrGlu: 2.603 ± 0.046	1.834ThrPhe: 1.834 ± 0.036	4.657ThrGly: 4.657 ± 0.065	0.989ThrHis: 0.989 ± 0.03	2.404ThrIle: 2.404 ± 0.058	1.617ThrLys: 1.617 ± 0.037	5.504ThrLeu: 5.504 ± 0.058	1.243ThrMet: 1.243 ± 0.034	1.21ThrAsn: 1.21 ± 0.034	2.847ThrPro: 2.847 ± 0.049	1.479ThrGln: 1.479 ± 0.036	3.031ThrArg: 3.031 ± 0.052	2.672ThrSer: 2.672 ± 0.053	2.408ThrThr: 2.408 ± 0.045	3.612ThrVal: 3.612 ± 0.062	0.586ThrTrp: 0.586 ± 0.02	1.221ThrTyr: 1.221 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	7.323ValAla: 7.323 ± 0.081	0.933ValCys: 0.933 ± 0.031	4.07ValAsp: 4.07 ± 0.058	4.617ValGlu: 4.617 ± 0.069	2.737ValPhe: 2.737 ± 0.052	5.182ValGly: 5.182 ± 0.069	1.438ValHis: 1.438 ± 0.035	3.37ValIle: 3.37 ± 0.053	2.439ValLys: 2.439 ± 0.047	8.518ValLeu: 8.518 ± 0.087	1.761ValMet: 1.761 ± 0.048	2.052ValAsn: 2.052 ± 0.043	3.215ValPro: 3.215 ± 0.055	2.436ValGln: 2.436 ± 0.051	5.451ValArg: 5.451 ± 0.066	4.419ValSer: 4.419 ± 0.067	3.701ValThr: 3.701 ± 0.061	5.295ValVal: 5.295 ± 0.077	0.805ValTrp: 0.805 ± 0.026	1.707ValTyr: 1.707 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.066TrpAla: 1.066 ± 0.032	0.148TrpCys: 0.148 ± 0.011	0.634TrpAsp: 0.634 ± 0.026	0.712TrpGlu: 0.712 ± 0.022	0.488TrpPhe: 0.488 ± 0.019	0.864TrpGly: 0.864 ± 0.033	0.252TrpHis: 0.252 ± 0.015	0.598TrpIle: 0.598 ± 0.024	0.496TrpLys: 0.496 ± 0.021	1.581TrpLeu: 1.581 ± 0.038	0.296TrpMet: 0.296 ± 0.016	0.426TrpAsn: 0.426 ± 0.019	0.703TrpPro: 0.703 ± 0.025	0.53TrpGln: 0.53 ± 0.023	1.054TrpArg: 1.054 ± 0.031	0.727TrpSer: 0.727 ± 0.025	0.595TrpThr: 0.595 ± 0.023	0.791TrpVal: 0.791 ± 0.026	0.21TrpTrp: 0.21 ± 0.014	0.277TrpTyr: 0.277 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.487TyrAla: 2.487 ± 0.044	0.367TyrCys: 0.367 ± 0.019	1.344TyrAsp: 1.344 ± 0.039	1.414TyrGlu: 1.414 ± 0.036	1.102TyrPhe: 1.102 ± 0.032	2.099TyrGly: 2.099 ± 0.043	0.499TyrHis: 0.499 ± 0.024	1.072TyrIle: 1.072 ± 0.033	0.898TyrLys: 0.898 ± 0.031	2.858TyrLeu: 2.858 ± 0.047	0.602TyrMet: 0.602 ± 0.025	0.677TyrAsn: 0.677 ± 0.025	1.24TyrPro: 1.24 ± 0.029	0.816TyrGln: 0.816 ± 0.03	1.715TyrArg: 1.715 ± 0.037	1.449TyrSer: 1.449 ± 0.037	1.214TyrThr: 1.214 ± 0.032	1.709TyrVal: 1.709 ± 0.031	0.366TyrTrp: 0.366 ± 0.018	0.807TyrTyr: 0.807 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3699 proteins (1178996 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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