Amino acid dipepetide frequency for Dolphin rhabdovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.536AlaAla: 2.536 ± 1.088
1.691AlaCys: 1.691 ± 0.547
4.227AlaAsp: 4.227 ± 1.07
3.381AlaGlu: 3.381 ± 1.81
0.845AlaPhe: 0.845 ± 0.71
1.409AlaGly: 1.409 ± 0.281
1.127AlaHis: 1.127 ± 0.29
5.072AlaIle: 5.072 ± 1.033
1.972AlaLys: 1.972 ± 1.562
6.199AlaLeu: 6.199 ± 1.24
0.282AlaMet: 0.282 ± 0.387
2.254AlaAsn: 2.254 ± 1.258
1.691AlaPro: 1.691 ± 0.454
2.254AlaGln: 2.254 ± 0.669
1.691AlaArg: 1.691 ± 0.711
2.818AlaSer: 2.818 ± 1.583
2.254AlaThr: 2.254 ± 0.807
2.254AlaVal: 2.254 ± 1.001
0.564AlaTrp: 0.564 ± 0.445
1.691AlaTyr: 1.691 ± 0.817
0.0AlaXaa: 0.0 ± 0.0
Cys
0.845CysAla: 0.845 ± 0.802
0.0CysCys: 0.0 ± 0.0
0.282CysAsp: 0.282 ± 0.381
0.845CysGlu: 0.845 ± 0.502
0.564CysPhe: 0.564 ± 0.445
1.127CysGly: 1.127 ± 0.628
0.564CysHis: 0.564 ± 0.317
1.127CysIle: 1.127 ± 0.445
1.127CysLys: 1.127 ± 0.628
1.127CysLeu: 1.127 ± 0.635
0.564CysMet: 0.564 ± 0.616
0.845CysAsn: 0.845 ± 0.476
0.845CysPro: 0.845 ± 1.142
0.564CysGln: 0.564 ± 0.314
0.282CysArg: 0.282 ± 0.387
1.127CysSer: 1.127 ± 0.928
0.282CysThr: 0.282 ± 0.159
1.127CysVal: 1.127 ± 0.635
0.564CysTrp: 0.564 ± 0.317
0.845CysTyr: 0.845 ± 0.648
0.0CysXaa: 0.0 ± 0.0
Asp
1.972AspAla: 1.972 ± 0.901
1.691AspCys: 1.691 ± 0.562
4.227AspAsp: 4.227 ± 2.631
3.663AspGlu: 3.663 ± 1.572
3.381AspPhe: 3.381 ± 0.693
4.227AspGly: 4.227 ± 1.496
1.691AspHis: 1.691 ± 0.646
1.409AspIle: 1.409 ± 0.591
3.099AspLys: 3.099 ± 2.055
7.326AspLeu: 7.326 ± 1.493
2.818AspMet: 2.818 ± 1.471
3.381AspAsn: 3.381 ± 0.837
2.536AspPro: 2.536 ± 0.49
2.536AspGln: 2.536 ± 0.902
2.536AspArg: 2.536 ± 0.923
2.818AspSer: 2.818 ± 0.568
2.254AspThr: 2.254 ± 1.323
2.254AspVal: 2.254 ± 0.807
2.254AspTrp: 2.254 ± 0.76
2.536AspTyr: 2.536 ± 0.772
0.0AspXaa: 0.0 ± 0.0
Glu
3.381GluAla: 3.381 ± 1.875
0.282GluCys: 0.282 ± 0.579
4.227GluAsp: 4.227 ± 0.876
5.635GluGlu: 5.635 ± 1.568
1.972GluPhe: 1.972 ± 0.707
4.227GluGly: 4.227 ± 1.666
1.409GluHis: 1.409 ± 0.591
4.227GluIle: 4.227 ± 0.49
4.508GluLys: 4.508 ± 0.999
4.79GluLeu: 4.79 ± 1.111
1.972GluMet: 1.972 ± 0.521
2.536GluAsn: 2.536 ± 0.806
1.409GluPro: 1.409 ± 0.609
1.127GluGln: 1.127 ± 0.603
3.381GluArg: 3.381 ± 1.052
5.072GluSer: 5.072 ± 0.89
7.326GluThr: 7.326 ± 1.685
4.227GluVal: 4.227 ± 0.808
1.691GluTrp: 1.691 ± 1.053
2.536GluTyr: 2.536 ± 0.547
0.0GluXaa: 0.0 ± 0.0
Phe
1.972PheAla: 1.972 ± 0.704
1.127PheCys: 1.127 ± 0.703
1.409PheAsp: 1.409 ± 0.793
1.972PheGlu: 1.972 ± 0.469
2.536PhePhe: 2.536 ± 0.75
2.536PheGly: 2.536 ± 0.568
1.127PheHis: 1.127 ± 0.535
2.536PheIle: 2.536 ± 0.753
3.945PheLys: 3.945 ± 2.22
3.945PheLeu: 3.945 ± 1.578
0.282PheMet: 0.282 ± 0.159
2.818PheAsn: 2.818 ± 0.532
1.972PhePro: 1.972 ± 0.937
1.127PheGln: 1.127 ± 0.445
4.227PheArg: 4.227 ± 0.984
2.818PheSer: 2.818 ± 0.9
1.409PheThr: 1.409 ± 1.057
1.409PheVal: 1.409 ± 0.42
0.282PheTrp: 0.282 ± 0.159
0.564PheTyr: 0.564 ± 0.339
0.0PheXaa: 0.0 ± 0.0
Gly
2.254GlyAla: 2.254 ± 1.899
0.0GlyCys: 0.0 ± 0.0
3.945GlyAsp: 3.945 ± 1.093
2.818GlyGlu: 2.818 ± 1.601
2.536GlyPhe: 2.536 ± 1.109
3.945GlyGly: 3.945 ± 0.833
1.691GlyHis: 1.691 ± 1.05
3.381GlyIle: 3.381 ± 1.318
4.227GlyLys: 4.227 ± 1.21
7.608GlyLeu: 7.608 ± 1.459
1.691GlyMet: 1.691 ± 0.943
1.972GlyAsn: 1.972 ± 0.789
2.254GlyPro: 2.254 ± 1.506
3.099GlyGln: 3.099 ± 0.864
1.972GlyArg: 1.972 ± 0.35
3.381GlySer: 3.381 ± 0.705
3.663GlyThr: 3.663 ± 1.31
3.099GlyVal: 3.099 ± 0.61
0.845GlyTrp: 0.845 ± 0.373
2.254GlyTyr: 2.254 ± 1.316
0.0GlyXaa: 0.0 ± 0.0
His
1.127HisAla: 1.127 ± 0.397
0.282HisCys: 0.282 ± 0.159
0.845HisAsp: 0.845 ± 0.476
1.691HisGlu: 1.691 ± 0.629
0.845HisPhe: 0.845 ± 0.476
0.282HisGly: 0.282 ± 0.579
0.564HisHis: 0.564 ± 0.317
3.099HisIle: 3.099 ± 1.082
1.127HisLys: 1.127 ± 0.635
2.254HisLeu: 2.254 ± 0.45
0.845HisMet: 0.845 ± 0.476
1.127HisAsn: 1.127 ± 0.628
2.818HisPro: 2.818 ± 0.972
1.409HisGln: 1.409 ± 0.609
1.972HisArg: 1.972 ± 0.473
1.127HisSer: 1.127 ± 0.628
0.564HisThr: 0.564 ± 0.747
1.127HisVal: 1.127 ± 0.635
1.127HisTrp: 1.127 ± 0.397
1.127HisTyr: 1.127 ± 0.498
0.0HisXaa: 0.0 ± 0.0
Ile
2.818IleAla: 2.818 ± 1.322
1.127IleCys: 1.127 ± 0.397
6.199IleAsp: 6.199 ± 2.096
5.635IleGlu: 5.635 ± 1.311
2.254IlePhe: 2.254 ± 0.793
5.072IleGly: 5.072 ± 1.025
1.409IleHis: 1.409 ± 0.988
3.945IleIle: 3.945 ± 1.018
5.072IleLys: 5.072 ± 1.658
6.199IleLeu: 6.199 ± 0.807
1.972IleMet: 1.972 ± 0.749
3.381IleAsn: 3.381 ± 1.292
3.381IlePro: 3.381 ± 0.859
3.099IleGln: 3.099 ± 0.464
4.508IleArg: 4.508 ± 1.455
4.79IleSer: 4.79 ± 0.997
3.099IleThr: 3.099 ± 0.855
2.818IleVal: 2.818 ± 0.546
1.972IleTrp: 1.972 ± 0.35
3.381IleTyr: 3.381 ± 0.693
0.0IleXaa: 0.0 ± 0.0
Lys
3.099LysAla: 3.099 ± 0.62
0.564LysCys: 0.564 ± 0.314
5.917LysAsp: 5.917 ± 1.836
5.072LysGlu: 5.072 ± 1.218
2.254LysPhe: 2.254 ± 0.937
5.072LysGly: 5.072 ± 1.659
1.409LysHis: 1.409 ± 0.698
6.199LysIle: 6.199 ± 0.749
2.536LysLys: 2.536 ± 1.088
7.326LysLeu: 7.326 ± 1.546
2.818LysMet: 2.818 ± 1.286
3.099LysAsn: 3.099 ± 1.201
3.945LysPro: 3.945 ± 1.383
1.972LysGln: 1.972 ± 0.654
2.818LysArg: 2.818 ± 0.582
4.508LysSer: 4.508 ± 1.875
4.227LysThr: 4.227 ± 1.401
2.818LysVal: 2.818 ± 0.546
0.845LysTrp: 0.845 ± 0.321
2.254LysTyr: 2.254 ± 0.663
0.0LysXaa: 0.0 ± 0.0
Leu
5.354LeuAla: 5.354 ± 1.022
0.564LeuCys: 0.564 ± 0.317
4.508LeuAsp: 4.508 ± 1.721
6.481LeuGlu: 6.481 ± 1.05
4.227LeuPhe: 4.227 ± 1.286
4.508LeuGly: 4.508 ± 0.892
1.972LeuHis: 1.972 ± 0.469
9.862LeuIle: 9.862 ± 3.645
9.58LeuLys: 9.58 ± 2.632
5.917LeuLeu: 5.917 ± 1.385
5.072LeuMet: 5.072 ± 0.603
6.199LeuAsn: 6.199 ± 2.118
3.381LeuPro: 3.381 ± 1.048
1.409LeuGln: 1.409 ± 0.615
5.635LeuArg: 5.635 ± 1.81
10.707LeuSer: 10.707 ± 1.567
6.199LeuThr: 6.199 ± 0.909
4.508LeuVal: 4.508 ± 0.966
0.282LeuTrp: 0.282 ± 0.381
1.691LeuTyr: 1.691 ± 0.707
0.0LeuXaa: 0.0 ± 0.0
Met
1.972MetAla: 1.972 ± 1.018
0.845MetCys: 0.845 ± 0.476
1.127MetAsp: 1.127 ± 0.445
1.409MetGlu: 1.409 ± 1.029
1.691MetPhe: 1.691 ± 0.574
1.972MetGly: 1.972 ± 0.905
0.0MetHis: 0.0 ± 0.0
1.972MetIle: 1.972 ± 0.61
1.127MetLys: 1.127 ± 1.157
1.409MetLeu: 1.409 ± 0.793
2.254MetMet: 2.254 ± 1.064
1.972MetAsn: 1.972 ± 0.463
1.972MetPro: 1.972 ± 0.711
0.282MetGln: 0.282 ± 0.159
2.536MetArg: 2.536 ± 0.583
4.508MetSer: 4.508 ± 0.759
2.254MetThr: 2.254 ± 0.528
1.691MetVal: 1.691 ± 0.688
0.282MetTrp: 0.282 ± 0.159
1.409MetTyr: 1.409 ± 0.838
0.0MetXaa: 0.0 ± 0.0
Asn
1.972AsnAla: 1.972 ± 0.654
0.564AsnCys: 0.564 ± 0.314
3.381AsnAsp: 3.381 ± 1.116
3.099AsnGlu: 3.099 ± 1.028
2.254AsnPhe: 2.254 ± 1.175
2.818AsnGly: 2.818 ± 1.01
1.972AsnHis: 1.972 ± 0.789
2.536AsnIle: 2.536 ± 1.0
5.354AsnLys: 5.354 ± 1.417
5.635AsnLeu: 5.635 ± 1.379
0.845AsnMet: 0.845 ± 0.885
2.536AsnAsn: 2.536 ± 0.772
2.818AsnPro: 2.818 ± 0.992
2.254AsnGln: 2.254 ± 1.269
1.691AsnArg: 1.691 ± 0.526
3.945AsnSer: 3.945 ± 0.546
2.254AsnThr: 2.254 ± 0.605
2.818AsnVal: 2.818 ± 0.866
0.845AsnTrp: 0.845 ± 0.68
1.409AsnTyr: 1.409 ± 0.609
0.0AsnXaa: 0.0 ± 0.0
Pro
2.818ProAla: 2.818 ± 0.898
0.564ProCys: 0.564 ± 0.317
4.227ProAsp: 4.227 ± 1.137
1.972ProGlu: 1.972 ± 0.463
2.254ProPhe: 2.254 ± 0.983
1.691ProGly: 1.691 ± 1.788
1.691ProHis: 1.691 ± 0.943
3.663ProIle: 3.663 ± 2.509
2.818ProLys: 2.818 ± 0.735
4.79ProLeu: 4.79 ± 0.99
1.409ProMet: 1.409 ± 0.624
1.409ProAsn: 1.409 ± 0.571
1.691ProPro: 1.691 ± 1.385
0.282ProGln: 0.282 ± 0.159
1.972ProArg: 1.972 ± 0.535
5.354ProSer: 5.354 ± 0.596
3.381ProThr: 3.381 ± 0.654
1.972ProVal: 1.972 ± 0.61
0.845ProTrp: 0.845 ± 0.476
2.254ProTyr: 2.254 ± 0.632
0.0ProXaa: 0.0 ± 0.0
Gln
1.409GlnAla: 1.409 ± 0.561
0.845GlnCys: 0.845 ± 1.035
0.564GlnAsp: 0.564 ± 0.339
2.254GlnGlu: 2.254 ± 0.498
1.127GlnPhe: 1.127 ± 0.535
2.254GlnGly: 2.254 ± 0.645
1.972GlnHis: 1.972 ± 0.463
1.409GlnIle: 1.409 ± 0.793
1.409GlnLys: 1.409 ± 0.523
3.381GlnLeu: 3.381 ± 0.705
1.127GlnMet: 1.127 ± 0.29
1.409GlnAsn: 1.409 ± 0.684
0.845GlnPro: 0.845 ± 0.476
0.282GlnGln: 0.282 ± 0.381
1.127GlnArg: 1.127 ± 0.635
3.099GlnSer: 3.099 ± 0.79
1.691GlnThr: 1.691 ± 0.817
2.254GlnVal: 2.254 ± 0.912
0.564GlnTrp: 0.564 ± 0.445
0.845GlnTyr: 0.845 ± 0.476
0.0GlnXaa: 0.0 ± 0.0
Arg
1.691ArgAla: 1.691 ± 0.646
1.409ArgCys: 1.409 ± 0.615
2.536ArgAsp: 2.536 ± 0.806
2.254ArgGlu: 2.254 ± 0.719
1.972ArgPhe: 1.972 ± 0.789
2.254ArgGly: 2.254 ± 1.026
1.127ArgHis: 1.127 ± 0.535
3.663ArgIle: 3.663 ± 0.29
4.227ArgLys: 4.227 ± 1.943
4.227ArgLeu: 4.227 ± 1.463
1.409ArgMet: 1.409 ± 0.52
2.818ArgAsn: 2.818 ± 1.586
2.818ArgPro: 2.818 ± 0.868
1.691ArgGln: 1.691 ± 0.725
4.227ArgArg: 4.227 ± 1.053
4.508ArgSer: 4.508 ± 0.665
3.099ArgThr: 3.099 ± 1.246
3.663ArgVal: 3.663 ± 0.737
1.127ArgTrp: 1.127 ± 0.397
2.254ArgTyr: 2.254 ± 0.567
0.0ArgXaa: 0.0 ± 0.0
Ser
5.354SerAla: 5.354 ± 0.948
0.845SerCys: 0.845 ± 0.321
3.945SerAsp: 3.945 ± 1.682
5.917SerGlu: 5.917 ± 0.563
3.381SerPhe: 3.381 ± 0.712
4.227SerGly: 4.227 ± 0.89
2.818SerHis: 2.818 ± 0.814
4.508SerIle: 4.508 ± 1.075
6.199SerLys: 6.199 ± 1.005
8.171SerLeu: 8.171 ± 1.206
1.409SerMet: 1.409 ± 0.589
4.508SerAsn: 4.508 ± 1.289
2.536SerPro: 2.536 ± 0.587
2.254SerGln: 2.254 ± 0.456
3.381SerArg: 3.381 ± 0.806
4.508SerSer: 4.508 ± 1.105
3.945SerThr: 3.945 ± 0.728
4.227SerVal: 4.227 ± 0.691
1.409SerTrp: 1.409 ± 0.512
2.536SerTyr: 2.536 ± 0.753
0.0SerXaa: 0.0 ± 0.0
Thr
1.972ThrAla: 1.972 ± 0.881
1.127ThrCys: 1.127 ± 0.928
2.818ThrAsp: 2.818 ± 0.9
3.945ThrGlu: 3.945 ± 0.812
1.409ThrPhe: 1.409 ± 0.281
3.663ThrGly: 3.663 ± 0.737
0.845ThrHis: 0.845 ± 0.321
4.79ThrIle: 4.79 ± 1.116
3.381ThrLys: 3.381 ± 1.001
6.762ThrLeu: 6.762 ± 1.152
1.691ThrMet: 1.691 ± 0.555
1.691ThrAsn: 1.691 ± 1.253
4.79ThrPro: 4.79 ± 3.462
1.127ThrGln: 1.127 ± 0.445
3.381ThrArg: 3.381 ± 1.651
3.663ThrSer: 3.663 ± 0.751
3.663ThrThr: 3.663 ± 1.333
3.099ThrVal: 3.099 ± 1.889
1.409ThrTrp: 1.409 ± 0.512
2.536ThrTyr: 2.536 ± 1.045
0.0ThrXaa: 0.0 ± 0.0
Val
1.127ValAla: 1.127 ± 1.335
1.127ValCys: 1.127 ± 0.29
1.972ValAsp: 1.972 ± 0.35
3.381ValGlu: 3.381 ± 1.157
1.409ValPhe: 1.409 ± 0.281
1.691ValGly: 1.691 ± 0.707
0.282ValHis: 0.282 ± 0.159
5.635ValIle: 5.635 ± 0.281
3.945ValLys: 3.945 ± 1.157
5.354ValLeu: 5.354 ± 1.692
3.099ValMet: 3.099 ± 0.835
3.663ValAsn: 3.663 ± 1.969
2.818ValPro: 2.818 ± 0.41
0.845ValGln: 0.845 ± 0.476
2.254ValArg: 2.254 ± 0.605
3.945ValSer: 3.945 ± 1.292
3.381ValThr: 3.381 ± 2.057
3.663ValVal: 3.663 ± 0.725
0.282ValTrp: 0.282 ± 0.159
2.536ValTyr: 2.536 ± 0.755
0.0ValXaa: 0.0 ± 0.0
Trp
1.127TrpAla: 1.127 ± 0.445
0.0TrpCys: 0.0 ± 0.0
0.564TrpAsp: 0.564 ± 0.996
1.691TrpGlu: 1.691 ± 0.92
1.409TrpPhe: 1.409 ± 0.822
1.972TrpGly: 1.972 ± 0.836
0.845TrpHis: 0.845 ± 0.502
0.282TrpIle: 0.282 ± 0.159
0.564TrpLys: 0.564 ± 0.317
0.845TrpLeu: 0.845 ± 0.321
0.0TrpMet: 0.0 ± 0.0
1.691TrpAsn: 1.691 ± 0.646
0.564TrpPro: 0.564 ± 0.317
0.282TrpGln: 0.282 ± 0.381
0.845TrpArg: 0.845 ± 0.476
1.691TrpSer: 1.691 ± 0.646
1.127TrpThr: 1.127 ± 0.989
1.691TrpVal: 1.691 ± 0.501
0.0TrpTrp: 0.0 ± 0.0
0.282TrpTyr: 0.282 ± 0.381
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.409TyrAla: 1.409 ± 0.543
0.0TyrCys: 0.0 ± 0.0
1.691TyrAsp: 1.691 ± 0.89
2.818TyrGlu: 2.818 ± 1.01
1.691TyrPhe: 1.691 ± 0.707
1.691TyrGly: 1.691 ± 0.641
0.845TyrHis: 0.845 ± 0.363
2.818TyrIle: 2.818 ± 0.845
2.536TyrLys: 2.536 ± 0.923
4.79TyrLeu: 4.79 ± 0.738
0.845TyrMet: 0.845 ± 0.71
1.691TyrAsn: 1.691 ± 1.004
1.972TyrPro: 1.972 ± 0.638
1.972TyrGln: 1.972 ± 0.473
2.536TyrArg: 2.536 ± 0.936
1.691TyrSer: 1.691 ± 0.694
1.691TyrThr: 1.691 ± 0.5
1.972TyrVal: 1.972 ± 0.473
0.282TyrTrp: 0.282 ± 0.498
1.409TyrTyr: 1.409 ± 1.227
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3550 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski