Amino acid dipepetide frequency for Porcine stool-associated circular virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.378AlaAla: 3.378 ± 2.105
0.0AlaCys: 0.0 ± 0.0
1.126AlaAsp: 1.126 ± 1.081
5.631AlaGlu: 5.631 ± 3.623
3.378AlaPhe: 3.378 ± 1.461
4.505AlaGly: 4.505 ± 2.807
2.252AlaHis: 2.252 ± 1.403
1.126AlaIle: 1.126 ± 0.702
7.883AlaLys: 7.883 ± 4.912
2.252AlaLeu: 2.252 ± 1.403
2.252AlaMet: 2.252 ± 1.664
1.126AlaAsn: 1.126 ± 0.702
4.505AlaPro: 4.505 ± 0.759
2.252AlaGln: 2.252 ± 1.403
2.252AlaArg: 2.252 ± 1.403
2.252AlaSer: 2.252 ± 1.403
1.126AlaThr: 1.126 ± 1.081
2.252AlaVal: 2.252 ± 0.379
2.252AlaTrp: 2.252 ± 2.162
3.378AlaTyr: 3.378 ± 2.105
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.126CysPhe: 1.126 ± 0.702
2.252CysGly: 2.252 ± 0.379
0.0CysHis: 0.0 ± 0.0
1.126CysIle: 1.126 ± 0.702
1.126CysLys: 1.126 ± 1.081
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.126CysPro: 1.126 ± 1.081
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.252AspAla: 2.252 ± 1.403
0.0AspCys: 0.0 ± 0.0
4.505AspAsp: 4.505 ± 0.759
4.505AspGlu: 4.505 ± 2.542
2.252AspPhe: 2.252 ± 0.379
5.631AspGly: 5.631 ± 5.406
1.126AspHis: 1.126 ± 1.081
3.378AspIle: 3.378 ± 2.105
3.378AspLys: 3.378 ± 1.461
2.252AspLeu: 2.252 ± 2.162
1.126AspMet: 1.126 ± 0.702
3.378AspAsn: 3.378 ± 2.105
3.378AspPro: 3.378 ± 0.322
1.126AspGln: 1.126 ± 1.081
1.126AspArg: 1.126 ± 0.702
3.378AspSer: 3.378 ± 2.105
1.126AspThr: 1.126 ± 0.702
1.126AspVal: 1.126 ± 0.702
1.126AspTrp: 1.126 ± 1.081
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.631GluAla: 5.631 ± 1.84
0.0GluCys: 0.0 ± 0.0
1.126GluAsp: 1.126 ± 1.081
10.135GluGlu: 10.135 ± 6.165
3.378GluPhe: 3.378 ± 0.322
2.252GluGly: 2.252 ± 0.379
0.0GluHis: 0.0 ± 0.0
2.252GluIle: 2.252 ± 0.379
6.757GluLys: 6.757 ± 6.487
9.009GluLeu: 9.009 ± 5.084
0.0GluMet: 0.0 ± 0.0
1.126GluAsn: 1.126 ± 1.081
2.252GluPro: 2.252 ± 2.162
3.378GluGln: 3.378 ± 1.461
4.505GluArg: 4.505 ± 1.024
3.378GluSer: 3.378 ± 0.322
5.631GluThr: 5.631 ± 0.057
2.252GluVal: 2.252 ± 0.379
0.0GluTrp: 0.0 ± 0.0
2.252GluTyr: 2.252 ± 1.403
0.0GluXaa: 0.0 ± 0.0
Phe
1.126PheAla: 1.126 ± 0.702
0.0PheCys: 0.0 ± 0.0
2.252PheAsp: 2.252 ± 0.379
1.126PheGlu: 1.126 ± 1.081
3.378PhePhe: 3.378 ± 2.105
2.252PheGly: 2.252 ± 1.403
0.0PheHis: 0.0 ± 0.0
3.378PheIle: 3.378 ± 0.322
1.126PheLys: 1.126 ± 0.702
4.505PheLeu: 4.505 ± 2.542
1.126PheMet: 1.126 ± 0.702
4.505PheAsn: 4.505 ± 2.807
1.126PhePro: 1.126 ± 1.081
2.252PheGln: 2.252 ± 2.162
3.378PheArg: 3.378 ± 0.322
1.126PheSer: 1.126 ± 0.702
3.378PheThr: 3.378 ± 2.105
1.126PheVal: 1.126 ± 0.702
1.126PheTrp: 1.126 ± 0.702
4.505PheTyr: 4.505 ± 2.807
0.0PheXaa: 0.0 ± 0.0
Gly
1.126GlyAla: 1.126 ± 0.702
0.0GlyCys: 0.0 ± 0.0
1.126GlyAsp: 1.126 ± 1.081
6.757GlyGlu: 6.757 ± 2.921
0.0GlyPhe: 0.0 ± 0.0
3.378GlyGly: 3.378 ± 0.322
0.0GlyHis: 0.0 ± 0.0
6.757GlyIle: 6.757 ± 0.644
4.505GlyLys: 4.505 ± 1.024
3.378GlyLeu: 3.378 ± 0.322
1.126GlyMet: 1.126 ± 0.702
4.505GlyAsn: 4.505 ± 1.024
3.378GlyPro: 3.378 ± 1.461
3.378GlyGln: 3.378 ± 1.461
1.126GlyArg: 1.126 ± 0.702
1.126GlySer: 1.126 ± 0.702
4.505GlyThr: 4.505 ± 0.759
6.757GlyVal: 6.757 ± 0.644
0.0GlyTrp: 0.0 ± 0.0
7.883GlyTyr: 7.883 ± 0.437
0.0GlyXaa: 0.0 ± 0.0
His
1.126HisAla: 1.126 ± 0.702
0.0HisCys: 0.0 ± 0.0
3.378HisAsp: 3.378 ± 0.322
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.126HisGly: 1.126 ± 0.702
0.0HisHis: 0.0 ± 0.0
1.126HisIle: 1.126 ± 1.081
1.126HisLys: 1.126 ± 0.702
4.505HisLeu: 4.505 ± 0.759
0.0HisMet: 0.0 ± 0.0
1.126HisAsn: 1.126 ± 0.702
1.126HisPro: 1.126 ± 0.702
1.126HisGln: 1.126 ± 0.702
1.126HisArg: 1.126 ± 0.702
1.126HisSer: 1.126 ± 0.702
0.0HisThr: 0.0 ± 0.0
1.126HisVal: 1.126 ± 0.702
0.0HisTrp: 0.0 ± 0.0
1.126HisTyr: 1.126 ± 1.081
0.0HisXaa: 0.0 ± 0.0
Ile
3.378IleAla: 3.378 ± 1.461
0.0IleCys: 0.0 ± 0.0
5.631IleAsp: 5.631 ± 1.84
7.883IleGlu: 7.883 ± 2.22
1.126IlePhe: 1.126 ± 1.081
1.126IleGly: 1.126 ± 0.702
0.0IleHis: 0.0 ± 0.0
5.631IleIle: 5.631 ± 3.623
6.757IleLys: 6.757 ± 0.644
3.378IleLeu: 3.378 ± 0.322
3.378IleMet: 3.378 ± 1.461
4.505IleAsn: 4.505 ± 2.807
3.378IlePro: 3.378 ± 2.105
0.0IleGln: 0.0 ± 0.0
3.378IleArg: 3.378 ± 1.461
1.126IleSer: 1.126 ± 1.081
5.631IleThr: 5.631 ± 3.623
1.126IleVal: 1.126 ± 0.702
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.631LysAla: 5.631 ± 1.84
0.0LysCys: 0.0 ± 0.0
3.378LysAsp: 3.378 ± 1.461
4.505LysGlu: 4.505 ± 1.024
2.252LysPhe: 2.252 ± 1.403
5.631LysGly: 5.631 ± 0.057
3.378LysHis: 3.378 ± 0.322
7.883LysIle: 7.883 ± 0.437
5.631LysLys: 5.631 ± 0.057
9.009LysLeu: 9.009 ± 5.084
2.252LysMet: 2.252 ± 0.379
6.757LysAsn: 6.757 ± 2.921
4.505LysPro: 4.505 ± 0.759
2.252LysGln: 2.252 ± 0.379
5.631LysArg: 5.631 ± 3.509
3.378LysSer: 3.378 ± 2.105
3.378LysThr: 3.378 ± 0.322
4.505LysVal: 4.505 ± 2.807
1.126LysTrp: 1.126 ± 0.702
5.631LysTyr: 5.631 ± 0.057
0.0LysXaa: 0.0 ± 0.0
Leu
3.378LeuAla: 3.378 ± 1.461
1.126LeuCys: 1.126 ± 1.081
4.505LeuAsp: 4.505 ± 2.542
3.378LeuGlu: 3.378 ± 3.244
2.252LeuPhe: 2.252 ± 0.379
3.378LeuGly: 3.378 ± 1.461
1.126LeuHis: 1.126 ± 0.702
2.252LeuIle: 2.252 ± 2.162
3.378LeuLys: 3.378 ± 2.105
5.631LeuLeu: 5.631 ± 3.623
3.378LeuMet: 3.378 ± 3.244
3.378LeuAsn: 3.378 ± 1.461
4.505LeuPro: 4.505 ± 1.024
3.378LeuGln: 3.378 ± 1.461
5.631LeuArg: 5.631 ± 3.623
7.883LeuSer: 7.883 ± 0.437
6.757LeuThr: 6.757 ± 1.138
2.252LeuVal: 2.252 ± 0.379
1.126LeuTrp: 1.126 ± 1.081
5.631LeuTyr: 5.631 ± 3.509
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
1.126MetCys: 1.126 ± 1.081
0.0MetAsp: 0.0 ± 0.0
1.126MetGlu: 1.126 ± 0.702
1.126MetPhe: 1.126 ± 0.702
1.126MetGly: 1.126 ± 0.702
2.252MetHis: 2.252 ± 1.403
1.126MetIle: 1.126 ± 1.081
1.126MetLys: 1.126 ± 0.702
1.126MetLeu: 1.126 ± 1.081
1.126MetMet: 1.126 ± 0.702
3.378MetAsn: 3.378 ± 1.461
2.252MetPro: 2.252 ± 1.403
1.126MetGln: 1.126 ± 0.702
1.126MetArg: 1.126 ± 1.081
6.757MetSer: 6.757 ± 0.644
1.126MetThr: 1.126 ± 0.702
3.378MetVal: 3.378 ± 0.322
1.126MetTrp: 1.126 ± 1.081
1.126MetTyr: 1.126 ± 0.702
0.0MetXaa: 0.0 ± 0.0
Asn
3.378AsnAla: 3.378 ± 2.105
0.0AsnCys: 0.0 ± 0.0
5.631AsnAsp: 5.631 ± 0.057
3.378AsnGlu: 3.378 ± 0.322
2.252AsnPhe: 2.252 ± 0.379
3.378AsnGly: 3.378 ± 1.461
0.0AsnHis: 0.0 ± 0.0
3.378AsnIle: 3.378 ± 0.322
7.883AsnLys: 7.883 ± 2.22
3.378AsnLeu: 3.378 ± 3.244
1.126AsnMet: 1.126 ± 1.117
2.252AsnAsn: 2.252 ± 0.379
5.631AsnPro: 5.631 ± 1.726
1.126AsnGln: 1.126 ± 0.702
1.126AsnArg: 1.126 ± 0.702
2.252AsnSer: 2.252 ± 1.403
2.252AsnThr: 2.252 ± 0.379
2.252AsnVal: 2.252 ± 1.403
2.252AsnTrp: 2.252 ± 0.379
1.126AsnTyr: 1.126 ± 0.702
0.0AsnXaa: 0.0 ± 0.0
Pro
2.252ProAla: 2.252 ± 2.162
1.126ProCys: 1.126 ± 0.702
1.126ProAsp: 1.126 ± 0.702
4.505ProGlu: 4.505 ± 2.542
5.631ProPhe: 5.631 ± 3.509
1.126ProGly: 1.126 ± 0.702
2.252ProHis: 2.252 ± 0.379
3.378ProIle: 3.378 ± 1.461
2.252ProLys: 2.252 ± 0.379
3.378ProLeu: 3.378 ± 0.322
2.252ProMet: 2.252 ± 1.403
2.252ProAsn: 2.252 ± 1.403
0.0ProPro: 0.0 ± 0.0
3.378ProGln: 3.378 ± 0.322
0.0ProArg: 0.0 ± 0.0
1.126ProSer: 1.126 ± 0.702
5.631ProThr: 5.631 ± 0.057
5.631ProVal: 5.631 ± 1.84
0.0ProTrp: 0.0 ± 0.0
5.631ProTyr: 5.631 ± 0.057
0.0ProXaa: 0.0 ± 0.0
Gln
1.126GlnAla: 1.126 ± 0.702
0.0GlnCys: 0.0 ± 0.0
2.252GlnAsp: 2.252 ± 1.403
3.378GlnGlu: 3.378 ± 1.461
3.378GlnPhe: 3.378 ± 1.461
1.126GlnGly: 1.126 ± 0.702
1.126GlnHis: 1.126 ± 0.702
2.252GlnIle: 2.252 ± 0.379
3.378GlnLys: 3.378 ± 1.461
6.757GlnLeu: 6.757 ± 0.644
0.0GlnMet: 0.0 ± 0.0
3.378GlnAsn: 3.378 ± 1.461
2.252GlnPro: 2.252 ± 0.379
0.0GlnGln: 0.0 ± 0.0
1.126GlnArg: 1.126 ± 0.702
0.0GlnSer: 0.0 ± 0.0
1.126GlnThr: 1.126 ± 0.702
3.378GlnVal: 3.378 ± 3.244
1.126GlnTrp: 1.126 ± 1.081
1.126GlnTyr: 1.126 ± 0.702
0.0GlnXaa: 0.0 ± 0.0
Arg
5.631ArgAla: 5.631 ± 1.726
0.0ArgCys: 0.0 ± 0.0
1.126ArgAsp: 1.126 ± 0.702
0.0ArgGlu: 0.0 ± 0.0
2.252ArgPhe: 2.252 ± 1.403
3.378ArgGly: 3.378 ± 1.461
0.0ArgHis: 0.0 ± 0.0
1.126ArgIle: 1.126 ± 0.702
7.883ArgLys: 7.883 ± 0.437
7.883ArgLeu: 7.883 ± 0.437
0.0ArgMet: 0.0 ± 0.0
2.252ArgAsn: 2.252 ± 0.379
2.252ArgPro: 2.252 ± 1.403
3.378ArgGln: 3.378 ± 1.461
3.378ArgArg: 3.378 ± 0.322
1.126ArgSer: 1.126 ± 0.702
3.378ArgThr: 3.378 ± 0.322
0.0ArgVal: 0.0 ± 0.0
2.252ArgTrp: 2.252 ± 0.379
4.505ArgTyr: 4.505 ± 2.807
0.0ArgXaa: 0.0 ± 0.0
Ser
5.631SerAla: 5.631 ± 3.509
0.0SerCys: 0.0 ± 0.0
2.252SerAsp: 2.252 ± 1.403
3.378SerGlu: 3.378 ± 2.105
2.252SerPhe: 2.252 ± 1.403
2.252SerGly: 2.252 ± 1.403
0.0SerHis: 0.0 ± 0.0
2.252SerIle: 2.252 ± 1.403
9.009SerLys: 9.009 ± 2.048
2.252SerLeu: 2.252 ± 0.379
4.505SerMet: 4.505 ± 1.024
3.378SerAsn: 3.378 ± 2.105
3.378SerPro: 3.378 ± 0.322
1.126SerGln: 1.126 ± 0.702
4.505SerArg: 4.505 ± 2.807
6.757SerSer: 6.757 ± 2.427
2.252SerThr: 2.252 ± 1.403
2.252SerVal: 2.252 ± 2.162
1.126SerTrp: 1.126 ± 0.702
4.505SerTyr: 4.505 ± 1.024
0.0SerXaa: 0.0 ± 0.0
Thr
2.252ThrAla: 2.252 ± 0.379
1.126ThrCys: 1.126 ± 0.702
1.126ThrAsp: 1.126 ± 1.081
0.0ThrGlu: 0.0 ± 0.0
1.126ThrPhe: 1.126 ± 0.702
10.135ThrGly: 10.135 ± 0.816
2.252ThrHis: 2.252 ± 0.379
1.126ThrIle: 1.126 ± 1.081
2.252ThrLys: 2.252 ± 0.379
2.252ThrLeu: 2.252 ± 0.379
2.252ThrMet: 2.252 ± 1.403
3.378ThrAsn: 3.378 ± 0.322
3.378ThrPro: 3.378 ± 1.461
5.631ThrGln: 5.631 ± 1.726
3.378ThrArg: 3.378 ± 0.322
5.631ThrSer: 5.631 ± 3.509
9.009ThrThr: 9.009 ± 2.048
3.378ThrVal: 3.378 ± 0.322
0.0ThrTrp: 0.0 ± 0.0
4.505ThrTyr: 4.505 ± 1.024
0.0ThrXaa: 0.0 ± 0.0
Val
2.252ValAla: 2.252 ± 0.379
1.126ValCys: 1.126 ± 1.081
1.126ValAsp: 1.126 ± 0.702
3.378ValGlu: 3.378 ± 1.461
0.0ValPhe: 0.0 ± 0.0
2.252ValGly: 2.252 ± 1.403
0.0ValHis: 0.0 ± 0.0
5.631ValIle: 5.631 ± 5.406
4.505ValLys: 4.505 ± 2.542
0.0ValLeu: 0.0 ± 0.0
2.252ValMet: 2.252 ± 1.403
1.126ValAsn: 1.126 ± 0.702
3.378ValPro: 3.378 ± 0.322
0.0ValGln: 0.0 ± 0.0
4.505ValArg: 4.505 ± 0.759
7.883ValSer: 7.883 ± 4.912
4.505ValThr: 4.505 ± 2.807
1.126ValVal: 1.126 ± 0.702
0.0ValTrp: 0.0 ± 0.0
4.505ValTyr: 4.505 ± 0.759
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.126TrpAsp: 1.126 ± 1.081
1.126TrpGlu: 1.126 ± 1.081
1.126TrpPhe: 1.126 ± 1.081
0.0TrpGly: 0.0 ± 0.0
2.252TrpHis: 2.252 ± 1.403
1.126TrpIle: 1.126 ± 1.081
2.252TrpLys: 2.252 ± 0.379
1.126TrpLeu: 1.126 ± 1.081
1.126TrpMet: 1.126 ± 1.081
1.126TrpAsn: 1.126 ± 1.081
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.252TrpSer: 2.252 ± 1.403
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
2.252TrpTyr: 2.252 ± 0.379
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.631TyrAla: 5.631 ± 3.509
1.126TyrCys: 1.126 ± 0.702
3.378TyrAsp: 3.378 ± 2.105
1.126TyrGlu: 1.126 ± 0.702
4.505TyrPhe: 4.505 ± 2.807
4.505TyrGly: 4.505 ± 0.759
2.252TyrHis: 2.252 ± 0.379
1.126TyrIle: 1.126 ± 0.702
4.505TyrLys: 4.505 ± 2.807
2.252TyrLeu: 2.252 ± 1.403
2.252TyrMet: 2.252 ± 1.403
2.252TyrAsn: 2.252 ± 2.162
1.126TyrPro: 1.126 ± 0.702
3.378TyrGln: 3.378 ± 1.461
4.505TyrArg: 4.505 ± 0.759
4.505TyrSer: 4.505 ± 1.024
3.378TyrThr: 3.378 ± 2.105
5.631TyrVal: 5.631 ± 0.057
2.252TyrTrp: 2.252 ± 0.379
1.126TyrTyr: 1.126 ± 1.081
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (889 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski