Amino acid dipepetide frequency for Shinobi tetravirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.765AlaAla: 6.765 ± 3.224
2.46AlaCys: 2.46 ± 0.859
0.615AlaAsp: 0.615 ± 0.356
4.92AlaGlu: 4.92 ± 1.719
3.075AlaPhe: 3.075 ± 1.407
7.38AlaGly: 7.38 ± 0.924
0.615AlaHis: 0.615 ± 0.632
3.69AlaIle: 3.69 ± 0.945
4.92AlaLys: 4.92 ± 2.847
7.38AlaLeu: 7.38 ± 0.924
0.615AlaMet: 0.615 ± 0.356
2.46AlaAsn: 2.46 ± 2.1
4.305AlaPro: 4.305 ± 1.026
2.46AlaGln: 2.46 ± 1.21
4.92AlaArg: 4.92 ± 1.455
4.305AlaSer: 4.305 ± 1.749
4.305AlaThr: 4.305 ± 2.989
5.535AlaVal: 5.535 ± 0.704
0.615AlaTrp: 0.615 ± 0.356
3.69AlaTyr: 3.69 ± 0.945
0.0AlaXaa: 0.0 ± 0.0
Cys
3.075CysAla: 3.075 ± 0.83
0.615CysCys: 0.615 ± 0.632
3.075CysAsp: 3.075 ± 0.671
2.46CysGlu: 2.46 ± 0.859
2.46CysPhe: 2.46 ± 1.153
1.845CysGly: 1.845 ± 1.02
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.845CysLys: 1.845 ± 0.473
2.46CysLeu: 2.46 ± 0.859
1.845CysMet: 1.845 ± 0.473
1.23CysAsn: 1.23 ± 0.43
1.23CysPro: 1.23 ± 0.43
0.0CysGln: 0.0 ± 0.0
1.845CysArg: 1.845 ± 1.02
1.23CysSer: 1.23 ± 0.43
2.46CysThr: 2.46 ± 1.153
1.23CysVal: 1.23 ± 1.264
0.0CysTrp: 0.0 ± 0.0
1.23CysTyr: 1.23 ± 1.264
0.0CysXaa: 0.0 ± 0.0
Asp
2.46AspAla: 2.46 ± 0.859
0.615AspCys: 0.615 ± 0.356
3.075AspAsp: 3.075 ± 0.671
1.845AspGlu: 1.845 ± 0.473
1.23AspPhe: 1.23 ± 0.712
8.61AspGly: 8.61 ± 2.21
0.0AspHis: 0.0 ± 0.0
1.845AspIle: 1.845 ± 1.02
3.075AspLys: 3.075 ± 1.407
4.305AspLeu: 4.305 ± 2.492
2.46AspMet: 2.46 ± 1.424
1.845AspAsn: 1.845 ± 0.473
3.075AspPro: 3.075 ± 0.671
0.615AspGln: 0.615 ± 0.632
3.075AspArg: 3.075 ± 1.03
2.46AspSer: 2.46 ± 0.718
0.615AspThr: 0.615 ± 0.356
1.23AspVal: 1.23 ± 1.092
0.615AspTrp: 0.615 ± 0.356
0.615AspTyr: 0.615 ± 0.356
0.0AspXaa: 0.0 ± 0.0
Glu
3.075GluAla: 3.075 ± 1.03
1.845GluCys: 1.845 ± 0.473
3.075GluAsp: 3.075 ± 0.83
3.075GluGlu: 3.075 ± 1.78
3.69GluPhe: 3.69 ± 1.364
4.92GluGly: 4.92 ± 2.054
1.23GluHis: 1.23 ± 1.092
2.46GluIle: 2.46 ± 0.727
1.23GluLys: 1.23 ± 0.712
4.305GluLeu: 4.305 ± 1.235
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
3.69GluPro: 3.69 ± 1.364
3.69GluGln: 3.69 ± 2.136
1.845GluArg: 1.845 ± 1.068
4.305GluSer: 4.305 ± 1.706
3.075GluThr: 3.075 ± 0.83
4.92GluVal: 4.92 ± 1.455
1.23GluTrp: 1.23 ± 0.712
0.615GluTyr: 0.615 ± 1.198
0.0GluXaa: 0.0 ± 0.0
Phe
4.92PheAla: 4.92 ± 0.394
2.46PheCys: 2.46 ± 0.718
3.075PheAsp: 3.075 ± 0.83
1.845PheGlu: 1.845 ± 0.928
0.0PhePhe: 0.0 ± 0.0
2.46PheGly: 2.46 ± 0.859
1.845PheHis: 1.845 ± 1.02
1.23PheIle: 1.23 ± 1.092
1.845PheLys: 1.845 ± 1.096
6.15PheLeu: 6.15 ± 3.983
1.23PheMet: 1.23 ± 0.537
0.0PheAsn: 0.0 ± 0.0
1.845PhePro: 1.845 ± 1.096
0.0PheGln: 0.0 ± 0.0
1.23PheArg: 1.23 ± 0.43
4.305PheSer: 4.305 ± 0.262
3.075PheThr: 3.075 ± 0.83
3.69PheVal: 3.69 ± 2.192
0.615PheTrp: 0.615 ± 0.356
1.23PheTyr: 1.23 ± 1.203
0.0PheXaa: 0.0 ± 0.0
Gly
4.92GlyAla: 4.92 ± 2.054
5.535GlyCys: 5.535 ± 1.652
3.075GlyAsp: 3.075 ± 1.78
1.23GlyGlu: 1.23 ± 0.712
3.69GlyPhe: 3.69 ± 0.79
5.535GlyGly: 5.535 ± 1.961
0.615GlyHis: 0.615 ± 0.632
1.23GlyIle: 1.23 ± 0.43
3.69GlyLys: 3.69 ± 2.899
11.685GlyLeu: 11.685 ± 2.965
1.845GlyMet: 1.845 ± 0.867
2.46GlyAsn: 2.46 ± 0.859
4.305GlyPro: 4.305 ± 3.529
1.23GlyGln: 1.23 ± 0.712
4.305GlyArg: 4.305 ± 1.706
4.305GlySer: 4.305 ± 1.749
6.15GlyThr: 6.15 ± 2.891
6.15GlyVal: 6.15 ± 1.787
0.615GlyTrp: 0.615 ± 0.632
0.615GlyTyr: 0.615 ± 0.632
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.845HisCys: 1.845 ± 1.896
2.46HisAsp: 2.46 ± 1.424
1.23HisGlu: 1.23 ± 0.43
0.615HisPhe: 0.615 ± 0.632
2.46HisGly: 2.46 ± 1.424
0.615HisHis: 0.615 ± 0.632
0.0HisIle: 0.0 ± 0.0
3.075HisLys: 3.075 ± 1.407
1.23HisLeu: 1.23 ± 0.43
0.615HisMet: 0.615 ± 0.632
0.0HisAsn: 0.0 ± 0.0
1.845HisPro: 1.845 ± 1.896
0.615HisGln: 0.615 ± 0.356
1.23HisArg: 1.23 ± 0.43
1.845HisSer: 1.845 ± 1.02
1.845HisThr: 1.845 ± 0.473
0.0HisVal: 0.0 ± 0.0
1.23HisTrp: 1.23 ± 0.43
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.845IleAla: 1.845 ± 1.096
0.0IleCys: 0.0 ± 0.0
3.69IleAsp: 3.69 ± 1.364
0.615IleGlu: 0.615 ± 0.356
1.23IlePhe: 1.23 ± 2.397
0.615IleGly: 0.615 ± 1.198
0.615IleHis: 0.615 ± 0.356
1.23IleIle: 1.23 ± 1.092
2.46IleLys: 2.46 ± 0.727
1.845IleLeu: 1.845 ± 2.265
1.23IleMet: 1.23 ± 0.712
1.845IleAsn: 1.845 ± 1.068
4.92IlePro: 4.92 ± 1.719
1.845IleGln: 1.845 ± 1.096
2.46IleArg: 2.46 ± 1.153
4.92IleSer: 4.92 ± 0.558
0.0IleThr: 0.0 ± 0.0
1.845IleVal: 1.845 ± 1.02
0.0IleTrp: 0.0 ± 0.0
1.23IleTyr: 1.23 ± 0.712
0.0IleXaa: 0.0 ± 0.0
Lys
3.69LysAla: 3.69 ± 1.364
0.615LysCys: 0.615 ± 0.356
3.69LysAsp: 3.69 ± 1.658
3.69LysGlu: 3.69 ± 0.945
2.46LysPhe: 2.46 ± 1.424
3.075LysGly: 3.075 ± 1.03
1.23LysHis: 1.23 ± 0.712
1.23LysIle: 1.23 ± 0.712
5.535LysLys: 5.535 ± 2.564
3.075LysLeu: 3.075 ± 0.671
0.0LysMet: 0.0 ± 0.0
1.845LysAsn: 1.845 ± 1.068
5.535LysPro: 5.535 ± 1.163
3.69LysGln: 3.69 ± 1.805
1.845LysArg: 1.845 ± 1.096
4.92LysSer: 4.92 ± 0.558
3.075LysThr: 3.075 ± 1.78
3.69LysVal: 3.69 ± 1.364
3.69LysTrp: 3.69 ± 1.805
1.23LysTyr: 1.23 ± 1.092
0.0LysXaa: 0.0 ± 0.0
Leu
4.92LeuAla: 4.92 ± 0.394
4.305LeuCys: 4.305 ± 1.996
4.305LeuAsp: 4.305 ± 1.235
3.69LeuGlu: 3.69 ± 1.658
5.535LeuPhe: 5.535 ± 0.238
7.38LeuGly: 7.38 ± 2.798
3.075LeuHis: 3.075 ± 0.83
7.38LeuIle: 7.38 ± 2.414
4.92LeuLys: 4.92 ± 2.054
9.225LeuLeu: 9.225 ± 3.39
1.845LeuMet: 1.845 ± 0.473
1.23LeuAsn: 1.23 ± 0.43
9.225LeuPro: 9.225 ± 1.495
3.69LeuGln: 3.69 ± 0.945
2.46LeuArg: 2.46 ± 0.718
7.38LeuSer: 7.38 ± 2.414
4.305LeuThr: 4.305 ± 1.996
9.225LeuVal: 9.225 ± 1.713
0.615LeuTrp: 0.615 ± 1.198
1.845LeuTyr: 1.845 ± 1.02
0.0LeuXaa: 0.0 ± 0.0
Met
1.23MetAla: 1.23 ± 1.203
0.615MetCys: 0.615 ± 0.356
0.615MetAsp: 0.615 ± 0.356
1.23MetGlu: 1.23 ± 0.712
1.23MetPhe: 1.23 ± 0.43
2.46MetGly: 2.46 ± 0.859
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.23MetLys: 1.23 ± 0.712
0.0MetLeu: 0.0 ± 0.0
1.23MetMet: 1.23 ± 0.712
1.23MetAsn: 1.23 ± 0.712
1.23MetPro: 1.23 ± 0.43
1.23MetGln: 1.23 ± 0.712
1.23MetArg: 1.23 ± 0.712
2.46MetSer: 2.46 ± 0.718
0.0MetThr: 0.0 ± 0.0
1.23MetVal: 1.23 ± 0.43
0.615MetTrp: 0.615 ± 0.356
1.23MetTyr: 1.23 ± 0.712
0.0MetXaa: 0.0 ± 0.0
Asn
4.305AsnAla: 4.305 ± 1.026
0.615AsnCys: 0.615 ± 0.632
1.23AsnAsp: 1.23 ± 0.712
1.23AsnGlu: 1.23 ± 0.712
0.0AsnPhe: 0.0 ± 0.0
0.615AsnGly: 0.615 ± 0.356
1.23AsnHis: 1.23 ± 1.264
0.615AsnIle: 0.615 ± 1.198
1.23AsnLys: 1.23 ± 0.712
1.845AsnLeu: 1.845 ± 1.068
1.23AsnMet: 1.23 ± 0.624
1.23AsnAsn: 1.23 ± 2.397
2.46AsnPro: 2.46 ± 1.642
1.23AsnGln: 1.23 ± 0.43
0.615AsnArg: 0.615 ± 0.356
2.46AsnSer: 2.46 ± 0.859
0.615AsnThr: 0.615 ± 1.198
1.23AsnVal: 1.23 ± 1.264
0.615AsnTrp: 0.615 ± 0.356
0.615AsnTyr: 0.615 ± 0.356
0.0AsnXaa: 0.0 ± 0.0
Pro
7.38ProAla: 7.38 ± 0.924
1.23ProCys: 1.23 ± 1.264
1.845ProAsp: 1.845 ± 0.473
4.305ProGlu: 4.305 ± 1.706
1.845ProPhe: 1.845 ± 1.068
4.305ProGly: 4.305 ± 1.162
1.845ProHis: 1.845 ± 1.02
3.69ProIle: 3.69 ± 0.79
3.69ProLys: 3.69 ± 0.485
6.15ProLeu: 6.15 ± 3.223
0.615ProMet: 0.615 ± 0.356
1.845ProAsn: 1.845 ± 0.473
4.92ProPro: 4.92 ± 1.281
1.845ProGln: 1.845 ± 0.928
3.69ProArg: 3.69 ± 0.945
5.535ProSer: 5.535 ± 1.163
8.61ProThr: 8.61 ± 2.506
4.92ProVal: 4.92 ± 1.484
2.46ProTrp: 2.46 ± 2.528
3.075ProTyr: 3.075 ± 0.83
0.0ProXaa: 0.0 ± 0.0
Gln
4.92GlnAla: 4.92 ± 1.688
1.845GlnCys: 1.845 ± 1.02
1.23GlnAsp: 1.23 ± 0.43
1.845GlnGlu: 1.845 ± 1.068
2.46GlnPhe: 2.46 ± 1.21
0.615GlnGly: 0.615 ± 1.198
2.46GlnHis: 2.46 ± 1.424
0.615GlnIle: 0.615 ± 1.198
1.845GlnLys: 1.845 ± 0.473
3.69GlnLeu: 3.69 ± 0.79
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.845GlnPro: 1.845 ± 1.096
2.46GlnGln: 2.46 ± 1.424
3.075GlnArg: 3.075 ± 1.03
0.615GlnSer: 0.615 ± 0.356
1.23GlnThr: 1.23 ± 0.43
2.46GlnVal: 2.46 ± 1.153
0.615GlnTrp: 0.615 ± 1.198
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.075ArgAla: 3.075 ± 1.407
0.615ArgCys: 0.615 ± 0.632
1.23ArgAsp: 1.23 ± 0.712
2.46ArgGlu: 2.46 ± 1.424
2.46ArgPhe: 2.46 ± 1.642
4.305ArgGly: 4.305 ± 1.026
1.23ArgHis: 1.23 ± 0.712
0.615ArgIle: 0.615 ± 0.356
4.305ArgLys: 4.305 ± 1.749
4.92ArgLeu: 4.92 ± 1.281
1.23ArgMet: 1.23 ± 0.712
1.845ArgAsn: 1.845 ± 0.928
3.075ArgPro: 3.075 ± 0.671
1.845ArgGln: 1.845 ± 2.317
2.46ArgArg: 2.46 ± 1.966
4.305ArgSer: 4.305 ± 0.905
6.765ArgThr: 6.765 ± 1.743
3.69ArgVal: 3.69 ± 0.945
0.0ArgTrp: 0.0 ± 0.0
2.46ArgTyr: 2.46 ± 0.859
0.0ArgXaa: 0.0 ± 0.0
Ser
6.765SerAla: 6.765 ± 2.601
2.46SerCys: 2.46 ± 1.153
1.845SerAsp: 1.845 ± 1.02
7.38SerGlu: 7.38 ± 2.938
2.46SerPhe: 2.46 ± 0.718
4.92SerGly: 4.92 ± 1.281
1.845SerHis: 1.845 ± 0.473
1.845SerIle: 1.845 ± 0.928
3.69SerLys: 3.69 ± 2.136
6.765SerLeu: 6.765 ± 0.986
0.0SerMet: 0.0 ± 0.0
2.46SerAsn: 2.46 ± 0.859
6.15SerPro: 6.15 ± 1.964
1.23SerGln: 1.23 ± 0.43
6.15SerArg: 6.15 ± 4.317
3.075SerSer: 3.075 ± 0.83
5.535SerThr: 5.535 ± 3.025
5.535SerVal: 5.535 ± 1.652
0.615SerTrp: 0.615 ± 0.632
2.46SerTyr: 2.46 ± 1.153
0.0SerXaa: 0.0 ± 0.0
Thr
6.15ThrAla: 6.15 ± 1.043
0.615ThrCys: 0.615 ± 0.356
1.845ThrAsp: 1.845 ± 0.473
1.23ThrGlu: 1.23 ± 0.712
3.075ThrPhe: 3.075 ± 3.291
2.46ThrGly: 2.46 ± 0.859
3.075ThrHis: 3.075 ± 0.83
2.46ThrIle: 2.46 ± 0.727
3.075ThrLys: 3.075 ± 1.03
9.84ThrLeu: 9.84 ± 2.076
0.615ThrMet: 0.615 ± 0.632
0.615ThrAsn: 0.615 ± 0.356
2.46ThrPro: 2.46 ± 2.528
1.845ThrGln: 1.845 ± 0.928
2.46ThrArg: 2.46 ± 1.153
6.765ThrSer: 6.765 ± 2.193
14.76ThrThr: 14.76 ± 13.369
6.765ThrVal: 6.765 ± 0.554
0.615ThrTrp: 0.615 ± 0.356
1.845ThrTyr: 1.845 ± 0.473
0.0ThrXaa: 0.0 ± 0.0
Val
2.46ValAla: 2.46 ± 2.183
0.615ValCys: 0.615 ± 0.632
2.46ValAsp: 2.46 ± 0.718
5.535ValGlu: 5.535 ± 2.403
3.69ValPhe: 3.69 ± 2.317
5.535ValGly: 5.535 ± 3.911
1.23ValHis: 1.23 ± 1.264
1.845ValIle: 1.845 ± 1.068
3.69ValLys: 3.69 ± 1.805
5.535ValLeu: 5.535 ± 1.418
1.23ValMet: 1.23 ± 0.43
1.845ValAsn: 1.845 ± 0.473
7.995ValPro: 7.995 ± 1.308
3.075ValGln: 3.075 ± 0.81
4.92ValArg: 4.92 ± 1.719
5.535ValSer: 5.535 ± 3.194
2.46ValThr: 2.46 ± 0.727
7.995ValVal: 7.995 ± 3.113
1.845ValTrp: 1.845 ± 0.473
3.69ValTyr: 3.69 ± 1.364
0.0ValXaa: 0.0 ± 0.0
Trp
1.23TrpAla: 1.23 ± 1.092
0.615TrpCys: 0.615 ± 0.632
0.0TrpAsp: 0.0 ± 0.0
1.23TrpGlu: 1.23 ± 0.43
1.845TrpPhe: 1.845 ± 0.473
1.23TrpGly: 1.23 ± 1.203
0.0TrpHis: 0.0 ± 0.0
1.23TrpIle: 1.23 ± 0.43
1.23TrpLys: 1.23 ± 1.092
1.845TrpLeu: 1.845 ± 1.096
1.23TrpMet: 1.23 ± 0.43
0.0TrpAsn: 0.0 ± 0.0
1.23TrpPro: 1.23 ± 0.43
0.0TrpGln: 0.0 ± 0.0
1.845TrpArg: 1.845 ± 0.473
0.615TrpSer: 0.615 ± 0.632
1.845TrpThr: 1.845 ± 1.068
0.615TrpVal: 0.615 ± 0.632
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.845TyrAla: 1.845 ± 1.068
0.615TyrCys: 0.615 ± 0.356
1.23TyrAsp: 1.23 ± 1.092
1.23TyrGlu: 1.23 ± 0.43
0.615TyrPhe: 0.615 ± 1.198
2.46TyrGly: 2.46 ± 1.21
0.0TyrHis: 0.0 ± 0.0
1.23TyrIle: 1.23 ± 0.43
1.23TyrLys: 1.23 ± 0.43
4.305TyrLeu: 4.305 ± 0.262
0.615TyrMet: 0.615 ± 0.356
1.23TyrAsn: 1.23 ± 0.43
2.46TyrPro: 2.46 ± 0.859
1.23TyrGln: 1.23 ± 0.43
1.23TyrArg: 1.23 ± 1.264
1.845TyrSer: 1.845 ± 1.02
1.845TyrThr: 1.845 ± 1.068
1.23TyrVal: 1.23 ± 1.264
1.23TyrTrp: 1.23 ± 0.43
0.615TyrTyr: 0.615 ± 0.632
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1627 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski