Amino acid dipepetide frequency for Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.464AlaAla: 5.464 ± 0.072	0.992AlaCys: 0.992 ± 0.028	4.114AlaAsp: 4.114 ± 0.052	4.632AlaGlu: 4.632 ± 0.066	3.023AlaPhe: 3.023 ± 0.048	5.103AlaGly: 5.103 ± 0.069	1.25AlaHis: 1.25 ± 0.027	4.496AlaIle: 4.496 ± 0.072	3.981AlaLys: 3.981 ± 0.063	6.386AlaLeu: 6.386 ± 0.078	1.934AlaMet: 1.934 ± 0.041	3.1AlaAsn: 3.1 ± 0.048	2.213AlaPro: 2.213 ± 0.041	2.497AlaGln: 2.497 ± 0.048	3.069AlaArg: 3.069 ± 0.057	4.215AlaSer: 4.215 ± 0.062	3.684AlaThr: 3.684 ± 0.055	4.673AlaVal: 4.673 ± 0.065	0.821AlaTrp: 0.821 ± 0.027	2.996AlaTyr: 2.996 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.736CysAla: 0.736 ± 0.021	0.258CysCys: 0.258 ± 0.013	0.658CysAsp: 0.658 ± 0.024	0.681CysGlu: 0.681 ± 0.023	0.69CysPhe: 0.69 ± 0.022	1.044CysGly: 1.044 ± 0.029	0.315CysHis: 0.315 ± 0.015	0.989CysIle: 0.989 ± 0.025	0.774CysLys: 0.774 ± 0.025	1.16CysLeu: 1.16 ± 0.03	0.39CysMet: 0.39 ± 0.018	0.609CysAsn: 0.609 ± 0.019	0.568CysPro: 0.568 ± 0.019	0.319CysGln: 0.319 ± 0.013	0.686CysArg: 0.686 ± 0.023	0.768CysSer: 0.768 ± 0.022	0.749CysThr: 0.749 ± 0.025	0.713CysVal: 0.713 ± 0.025	0.179CysTrp: 0.179 ± 0.012	0.594CysTyr: 0.594 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.851AspAla: 3.851 ± 0.067	0.656AspCys: 0.656 ± 0.017	2.567AspAsp: 2.567 ± 0.05	3.752AspGlu: 3.752 ± 0.052	3.006AspPhe: 3.006 ± 0.043	4.255AspGly: 4.255 ± 0.066	0.868AspHis: 0.868 ± 0.022	4.093AspIle: 4.093 ± 0.056	4.186AspLys: 4.186 ± 0.062	4.459AspLeu: 4.459 ± 0.06	1.684AspMet: 1.684 ± 0.035	2.812AspAsn: 2.812 ± 0.041	1.79AspPro: 1.79 ± 0.034	1.213AspGln: 1.213 ± 0.029	2.509AspArg: 2.509 ± 0.037	2.998AspSer: 2.998 ± 0.045	2.762AspThr: 2.762 ± 0.041	3.357AspVal: 3.357 ± 0.044	0.918AspTrp: 0.918 ± 0.025	2.983AspTyr: 2.983 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	4.785GluAla: 4.785 ± 0.076	0.693GluCys: 0.693 ± 0.021	3.324GluAsp: 3.324 ± 0.057	5.182GluGlu: 5.182 ± 0.066	2.449GluPhe: 2.449 ± 0.043	4.232GluGly: 4.232 ± 0.06	1.301GluHis: 1.301 ± 0.031	4.537GluIle: 4.537 ± 0.058	5.48GluLys: 5.48 ± 0.078	6.154GluLeu: 6.154 ± 0.07	2.072GluMet: 2.072 ± 0.036	3.766GluAsn: 3.766 ± 0.054	1.733GluPro: 1.733 ± 0.037	2.659GluGln: 2.659 ± 0.047	3.247GluArg: 3.247 ± 0.051	3.079GluSer: 3.079 ± 0.046	3.447GluThr: 3.447 ± 0.049	4.262GluVal: 4.262 ± 0.06	0.921GluTrp: 0.921 ± 0.028	2.856GluTyr: 2.856 ± 0.045	0.0GluXaa: 0.0 ± 0.0
Phe	2.924PheAla: 2.924 ± 0.049	0.703PheCys: 0.703 ± 0.022	2.659PheAsp: 2.659 ± 0.044	2.434PheGlu: 2.434 ± 0.039	2.251PhePhe: 2.251 ± 0.043	3.19PheGly: 3.19 ± 0.051	0.935PheHis: 0.935 ± 0.028	3.344PheIle: 3.344 ± 0.057	2.497PheLys: 2.497 ± 0.043	4.046PheLeu: 4.046 ± 0.06	1.32PheMet: 1.32 ± 0.036	2.473PheAsn: 2.473 ± 0.048	1.819PhePro: 1.819 ± 0.035	1.309PheGln: 1.309 ± 0.026	2.201PheArg: 2.201 ± 0.041	3.363PheSer: 3.363 ± 0.052	2.796PheThr: 2.796 ± 0.047	2.723PheVal: 2.723 ± 0.043	0.581PheTrp: 0.581 ± 0.02	2.108PheTyr: 2.108 ± 0.043	0.0PheXaa: 0.0 ± 0.0
Gly	4.197GlyAla: 4.197 ± 0.069	0.987GlyCys: 0.987 ± 0.027	3.338GlyAsp: 3.338 ± 0.05	4.254GlyGlu: 4.254 ± 0.061	3.17GlyPhe: 3.17 ± 0.05	4.783GlyGly: 4.783 ± 0.083	1.308GlyHis: 1.308 ± 0.034	5.399GlyIle: 5.399 ± 0.074	5.564GlyLys: 5.564 ± 0.062	5.707GlyLeu: 5.707 ± 0.069	2.276GlyMet: 2.276 ± 0.039	3.85GlyAsn: 3.85 ± 0.065	1.347GlyPro: 1.347 ± 0.033	2.071GlyGln: 2.071 ± 0.043	2.957GlyArg: 2.957 ± 0.049	3.861GlySer: 3.861 ± 0.057	4.277GlyThr: 4.277 ± 0.052	4.695GlyVal: 4.695 ± 0.061	1.09GlyTrp: 1.09 ± 0.031	3.516GlyTyr: 3.516 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.155HisAla: 1.155 ± 0.03	0.321HisCys: 0.321 ± 0.014	0.983HisAsp: 0.983 ± 0.028	1.048HisGlu: 1.048 ± 0.03	1.088HisPhe: 1.088 ± 0.029	1.235HisGly: 1.235 ± 0.03	0.531HisHis: 0.531 ± 0.021	1.6HisIle: 1.6 ± 0.031	1.166HisLys: 1.166 ± 0.031	1.815HisLeu: 1.815 ± 0.038	0.361HisMet: 0.361 ± 0.013	0.976HisAsn: 0.976 ± 0.023	1.104HisPro: 1.104 ± 0.03	0.644HisGln: 0.644 ± 0.023	0.951HisArg: 0.951 ± 0.028	1.203HisSer: 1.203 ± 0.028	1.21HisThr: 1.21 ± 0.03	1.078HisVal: 1.078 ± 0.025	0.288HisTrp: 0.288 ± 0.015	0.954HisTyr: 0.954 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	4.93IleAla: 4.93 ± 0.061	1.015IleCys: 1.015 ± 0.027	4.079IleAsp: 4.079 ± 0.055	4.321IleGlu: 4.321 ± 0.063	2.838IlePhe: 2.838 ± 0.054	4.588IleGly: 4.588 ± 0.066	1.461IleHis: 1.461 ± 0.031	4.681IleIle: 4.681 ± 0.08	4.191IleLys: 4.191 ± 0.06	6.004IleLeu: 6.004 ± 0.085	1.609IleMet: 1.609 ± 0.035	3.522IleAsn: 3.522 ± 0.05	3.148IlePro: 3.148 ± 0.047	2.219IleGln: 2.219 ± 0.042	3.587IleArg: 3.587 ± 0.058	4.632IleSer: 4.632 ± 0.067	4.058IleThr: 4.058 ± 0.058	4.16IleVal: 4.16 ± 0.064	0.802IleTrp: 0.802 ± 0.028	2.934IleTyr: 2.934 ± 0.046	0.0IleXaa: 0.0 ± 0.0
Lys	4.922LysAla: 4.922 ± 0.073	0.572LysCys: 0.572 ± 0.02	4.184LysAsp: 4.184 ± 0.048	6.27LysGlu: 6.27 ± 0.075	2.239LysPhe: 2.239 ± 0.032	4.749LysGly: 4.749 ± 0.064	1.27LysHis: 1.27 ± 0.031	4.248LysIle: 4.248 ± 0.054	5.161LysLys: 5.161 ± 0.074	5.446LysLeu: 5.446 ± 0.061	2.08LysMet: 2.08 ± 0.042	3.749LysAsn: 3.749 ± 0.051	2.118LysPro: 2.118 ± 0.04	2.568LysGln: 2.568 ± 0.042	3.196LysArg: 3.196 ± 0.053	3.299LysSer: 3.299 ± 0.056	3.584LysThr: 3.584 ± 0.046	4.411LysVal: 4.411 ± 0.061	0.79LysTrp: 0.79 ± 0.025	3.037LysTyr: 3.037 ± 0.049	0.0LysXaa: 0.0 ± 0.0
Leu	6.119LeuAla: 6.119 ± 0.073	1.397LeuCys: 1.397 ± 0.033	4.6LeuAsp: 4.6 ± 0.059	5.215LeuGlu: 5.215 ± 0.067	4.465LeuPhe: 4.465 ± 0.066	5.496LeuGly: 5.496 ± 0.075	1.788LeuHis: 1.788 ± 0.036	5.475LeuIle: 5.475 ± 0.079	6.486LeuLys: 6.486 ± 0.068	8.726LeuLeu: 8.726 ± 0.107	2.524LeuMet: 2.524 ± 0.042	4.767LeuAsn: 4.767 ± 0.06	4.117LeuPro: 4.117 ± 0.052	3.389LeuGln: 3.389 ± 0.053	4.052LeuArg: 4.052 ± 0.058	6.544LeuSer: 6.544 ± 0.084	5.13LeuThr: 5.13 ± 0.058	4.996LeuVal: 4.996 ± 0.062	1.126LeuTrp: 1.126 ± 0.028	3.76LeuTyr: 3.76 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	2.08MetAla: 2.08 ± 0.04	0.25MetCys: 0.25 ± 0.014	1.656MetAsp: 1.656 ± 0.031	2.028MetGlu: 2.028 ± 0.038	1.003MetPhe: 1.003 ± 0.028	1.863MetGly: 1.863 ± 0.037	0.473MetHis: 0.473 ± 0.02	1.67MetIle: 1.67 ± 0.033	2.761MetLys: 2.761 ± 0.04	2.465MetLeu: 2.465 ± 0.046	0.836MetMet: 0.836 ± 0.022	1.737MetAsn: 1.737 ± 0.034	1.169MetPro: 1.169 ± 0.026	1.062MetGln: 1.062 ± 0.022	1.358MetArg: 1.358 ± 0.036	1.498MetSer: 1.498 ± 0.032	1.499MetThr: 1.499 ± 0.036	1.641MetVal: 1.641 ± 0.036	0.288MetTrp: 0.288 ± 0.015	0.944MetTyr: 0.944 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.433AsnAla: 3.433 ± 0.052	0.536AsnCys: 0.536 ± 0.021	2.649AsnAsp: 2.649 ± 0.049	3.272AsnGlu: 3.272 ± 0.044	2.307AsnPhe: 2.307 ± 0.045	4.174AsnGly: 4.174 ± 0.058	1.04AsnHis: 1.04 ± 0.029	3.899AsnIle: 3.899 ± 0.054	3.418AsnLys: 3.418 ± 0.055	4.493AsnLeu: 4.493 ± 0.06	1.413AsnMet: 1.413 ± 0.028	2.728AsnAsn: 2.728 ± 0.048	2.542AsnPro: 2.542 ± 0.049	1.649AsnGln: 1.649 ± 0.036	2.607AsnArg: 2.607 ± 0.041	2.899AsnSer: 2.899 ± 0.045	2.81AsnThr: 2.81 ± 0.051	3.192AsnVal: 3.192 ± 0.047	0.721AsnTrp: 0.721 ± 0.024	2.54AsnTyr: 2.54 ± 0.05	0.0AsnXaa: 0.0 ± 0.0
Pro	2.806ProAla: 2.806 ± 0.051	0.421ProCys: 0.421 ± 0.019	2.607ProAsp: 2.607 ± 0.046	3.291ProGlu: 3.291 ± 0.045	1.874ProPhe: 1.874 ± 0.033	2.529ProGly: 2.529 ± 0.045	0.782ProHis: 0.782 ± 0.023	2.17ProIle: 2.17 ± 0.045	1.943ProLys: 1.943 ± 0.037	3.217ProLeu: 3.217 ± 0.047	0.978ProMet: 0.978 ± 0.023	1.614ProAsn: 1.614 ± 0.034	0.825ProPro: 0.825 ± 0.026	1.433ProGln: 1.433 ± 0.033	1.347ProArg: 1.347 ± 0.033	2.21ProSer: 2.21 ± 0.041	1.882ProThr: 1.882 ± 0.038	3.131ProVal: 3.131 ± 0.048	0.493ProTrp: 0.493 ± 0.018	1.735ProTyr: 1.735 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	2.445GlnAla: 2.445 ± 0.043	0.325GlnCys: 0.325 ± 0.015	1.664GlnAsp: 1.664 ± 0.031	2.448GlnGlu: 2.448 ± 0.039	1.303GlnPhe: 1.303 ± 0.029	2.101GlnGly: 2.101 ± 0.039	0.651GlnHis: 0.651 ± 0.022	2.323GlnIle: 2.323 ± 0.038	2.445GlnLys: 2.445 ± 0.043	3.279GlnLeu: 3.279 ± 0.049	1.008GlnMet: 1.008 ± 0.03	1.751GlnAsn: 1.751 ± 0.036	1.262GlnPro: 1.262 ± 0.034	1.558GlnGln: 1.558 ± 0.042	1.683GlnArg: 1.683 ± 0.035	1.924GlnSer: 1.924 ± 0.041	1.972GlnThr: 1.972 ± 0.039	2.084GlnVal: 2.084 ± 0.039	0.528GlnTrp: 0.528 ± 0.021	1.463GlnTyr: 1.463 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	2.631ArgAla: 2.631 ± 0.052	0.541ArgCys: 0.541 ± 0.022	2.069ArgAsp: 2.069 ± 0.041	3.084ArgGlu: 3.084 ± 0.051	2.332ArgPhe: 2.332 ± 0.043	2.485ArgGly: 2.485 ± 0.043	1.027ArgHis: 1.027 ± 0.028	3.714ArgIle: 3.714 ± 0.055	3.581ArgLys: 3.581 ± 0.056	4.45ArgLeu: 4.45 ± 0.068	1.613ArgMet: 1.613 ± 0.035	2.633ArgAsn: 2.633 ± 0.05	1.638ArgPro: 1.638 ± 0.04	1.891ArgGln: 1.891 ± 0.041	2.257ArgArg: 2.257 ± 0.044	2.466ArgSer: 2.466 ± 0.042	2.496ArgThr: 2.496 ± 0.042	2.584ArgVal: 2.584 ± 0.045	0.666ArgTrp: 0.666 ± 0.022	2.369ArgTyr: 2.369 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	4.026SerAla: 4.026 ± 0.053	0.858SerCys: 0.858 ± 0.025	3.16SerAsp: 3.16 ± 0.045	3.485SerGlu: 3.485 ± 0.046	3.353SerPhe: 3.353 ± 0.053	4.411SerGly: 4.411 ± 0.062	1.165SerHis: 1.165 ± 0.028	4.195SerIle: 4.195 ± 0.053	3.31SerLys: 3.31 ± 0.049	5.943SerLeu: 5.943 ± 0.076	1.54SerMet: 1.54 ± 0.031	2.726SerAsn: 2.726 ± 0.05	2.289SerPro: 2.289 ± 0.04	1.89SerGln: 1.89 ± 0.037	2.714SerArg: 2.714 ± 0.046	3.814SerSer: 3.814 ± 0.062	3.2SerThr: 3.2 ± 0.051	4.189SerVal: 4.189 ± 0.054	0.85SerTrp: 0.85 ± 0.025	2.832SerTyr: 2.832 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	3.936ThrAla: 3.936 ± 0.055	0.591ThrCys: 0.591 ± 0.021	3.526ThrAsp: 3.526 ± 0.05	3.395ThrGlu: 3.395 ± 0.05	2.777ThrPhe: 2.777 ± 0.045	4.399ThrGly: 4.399 ± 0.059	1.112ThrHis: 1.112 ± 0.028	3.867ThrIle: 3.867 ± 0.055	2.79ThrLys: 2.79 ± 0.047	5.458ThrLeu: 5.458 ± 0.06	1.226ThrMet: 1.226 ± 0.032	2.549ThrAsn: 2.549 ± 0.05	2.784ThrPro: 2.784 ± 0.047	1.757ThrGln: 1.757 ± 0.039	2.253ThrArg: 2.253 ± 0.033	3.187ThrSer: 3.187 ± 0.046	3.087ThrThr: 3.087 ± 0.051	3.985ThrVal: 3.985 ± 0.06	0.718ThrTrp: 0.718 ± 0.022	2.463ThrTyr: 2.463 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	4.322ValAla: 4.322 ± 0.052	0.995ValCys: 0.995 ± 0.024	3.538ValAsp: 3.538 ± 0.049	4.002ValGlu: 4.002 ± 0.055	2.79ValPhe: 2.79 ± 0.048	3.856ValGly: 3.856 ± 0.059	1.11ValHis: 1.11 ± 0.026	4.267ValIle: 4.267 ± 0.062	4.265ValLys: 4.265 ± 0.059	5.712ValLeu: 5.712 ± 0.064	1.749ValMet: 1.749 ± 0.038	3.41ValAsn: 3.41 ± 0.049	2.603ValPro: 2.603 ± 0.043	1.902ValGln: 1.902 ± 0.041	2.958ValArg: 2.958 ± 0.049	4.417ValSer: 4.417 ± 0.051	3.8ValThr: 3.8 ± 0.056	4.126ValVal: 4.126 ± 0.059	0.801ValTrp: 0.801 ± 0.026	2.656ValTyr: 2.656 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.807TrpAla: 0.807 ± 0.023	0.193TrpCys: 0.193 ± 0.011	0.71TrpAsp: 0.71 ± 0.024	0.907TrpGlu: 0.907 ± 0.027	0.579TrpPhe: 0.579 ± 0.019	1.045TrpGly: 1.045 ± 0.031	0.286TrpHis: 0.286 ± 0.014	0.89TrpIle: 0.89 ± 0.028	0.962TrpLys: 0.962 ± 0.031	1.227TrpLeu: 1.227 ± 0.031	0.482TrpMet: 0.482 ± 0.019	0.925TrpAsn: 0.925 ± 0.03	0.292TrpPro: 0.292 ± 0.014	0.514TrpGln: 0.514 ± 0.02	0.611TrpArg: 0.611 ± 0.021	0.776TrpSer: 0.776 ± 0.029	0.719TrpThr: 0.719 ± 0.024	0.736TrpVal: 0.736 ± 0.025	0.228TrpTrp: 0.228 ± 0.015	0.551TrpTyr: 0.551 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.07TyrAla: 3.07 ± 0.046	0.577TyrCys: 0.577 ± 0.021	2.633TyrAsp: 2.633 ± 0.04	2.479TyrGlu: 2.479 ± 0.046	2.139TyrPhe: 2.139 ± 0.04	3.11TyrGly: 3.11 ± 0.049	1.036TyrHis: 1.036 ± 0.025	2.918TyrIle: 2.918 ± 0.044	2.933TyrLys: 2.933 ± 0.053	4.027TyrLeu: 4.027 ± 0.067	1.186TyrMet: 1.186 ± 0.027	2.623TyrAsn: 2.623 ± 0.047	1.93TyrPro: 1.93 ± 0.037	1.674TyrGln: 1.674 ± 0.038	2.283TyrArg: 2.283 ± 0.041	2.798TyrSer: 2.798 ± 0.054	2.7TyrThr: 2.7 ± 0.048	2.545TyrVal: 2.545 ± 0.041	0.631TyrTrp: 0.631 ± 0.018	2.249TyrTyr: 2.249 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3982 proteins (1490209 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---