Amino acid dipepetide frequency for Narcissus mosaic virus (NMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.56AlaAla: 6.56 ± 1.567
1.23AlaCys: 1.23 ± 0.575
4.92AlaAsp: 4.92 ± 1.603
3.69AlaGlu: 3.69 ± 1.487
2.46AlaPhe: 2.46 ± 0.789
3.69AlaGly: 3.69 ± 0.943
1.23AlaHis: 1.23 ± 0.815
3.28AlaIle: 3.28 ± 0.817
5.33AlaLys: 5.33 ± 1.586
7.79AlaLeu: 7.79 ± 2.255
2.05AlaMet: 2.05 ± 0.775
5.74AlaAsn: 5.74 ± 1.06
3.69AlaPro: 3.69 ± 3.865
1.23AlaGln: 1.23 ± 0.644
3.28AlaArg: 3.28 ± 1.749
6.56AlaSer: 6.56 ± 1.122
4.92AlaThr: 4.92 ± 1.243
4.1AlaVal: 4.1 ± 2.118
0.82AlaTrp: 0.82 ± 0.589
3.28AlaTyr: 3.28 ± 1.292
0.0AlaXaa: 0.0 ± 0.0
Cys
1.23CysAla: 1.23 ± 1.465
0.41CysCys: 0.41 ± 0.214
0.41CysAsp: 0.41 ± 0.713
1.23CysGlu: 1.23 ± 0.528
0.0CysPhe: 0.0 ± 0.0
2.87CysGly: 2.87 ± 0.56
0.82CysHis: 0.82 ± 1.178
0.82CysIle: 0.82 ± 0.428
2.05CysLys: 2.05 ± 0.883
1.64CysLeu: 1.64 ± 0.669
0.82CysMet: 0.82 ± 0.951
0.82CysAsn: 0.82 ± 0.598
1.23CysPro: 1.23 ± 0.528
2.05CysGln: 2.05 ± 1.891
1.23CysArg: 1.23 ± 0.643
2.46CysSer: 2.46 ± 1.012
1.23CysThr: 1.23 ± 0.742
0.41CysVal: 0.41 ± 0.713
0.0CysTrp: 0.0 ± 0.0
1.23CysTyr: 1.23 ± 1.247
0.0CysXaa: 0.0 ± 0.0
Asp
2.46AspAla: 2.46 ± 0.536
1.64AspCys: 1.64 ± 0.669
2.05AspAsp: 2.05 ± 0.775
2.87AspGlu: 2.87 ± 0.959
3.28AspPhe: 3.28 ± 1.292
1.64AspGly: 1.64 ± 0.76
0.0AspHis: 0.0 ± 0.0
4.1AspIle: 4.1 ± 1.538
1.64AspLys: 1.64 ± 0.857
5.74AspLeu: 5.74 ± 2.195
1.23AspMet: 1.23 ± 0.643
2.05AspAsn: 2.05 ± 0.757
3.69AspPro: 3.69 ± 2.445
0.82AspGln: 0.82 ± 0.428
2.87AspArg: 2.87 ± 0.747
6.15AspSer: 6.15 ± 1.283
3.28AspThr: 3.28 ± 1.714
2.87AspVal: 2.87 ± 1.105
0.82AspTrp: 0.82 ± 0.428
1.64AspTyr: 1.64 ± 0.857
0.0AspXaa: 0.0 ± 0.0
Glu
3.69GluAla: 3.69 ± 1.928
0.41GluCys: 0.41 ± 0.214
4.92GluAsp: 4.92 ± 1.419
0.82GluGlu: 0.82 ± 0.428
2.05GluPhe: 2.05 ± 0.645
2.05GluGly: 2.05 ± 0.775
0.41GluHis: 0.41 ± 0.214
4.1GluIle: 4.1 ± 1.55
3.28GluLys: 3.28 ± 1.714
3.28GluLeu: 3.28 ± 1.127
0.0GluMet: 0.0 ± 0.0
1.23GluAsn: 1.23 ± 0.528
4.51GluPro: 4.51 ± 1.666
1.23GluGln: 1.23 ± 1.781
2.05GluArg: 2.05 ± 1.071
5.33GluSer: 5.33 ± 1.61
4.51GluThr: 4.51 ± 1.888
3.28GluVal: 3.28 ± 1.207
1.23GluTrp: 1.23 ± 0.643
1.23GluTyr: 1.23 ± 1.173
0.0GluXaa: 0.0 ± 0.0
Phe
2.46PheAla: 2.46 ± 1.182
3.28PheCys: 3.28 ± 0.918
2.87PheAsp: 2.87 ± 0.588
3.69PheGlu: 3.69 ± 0.859
2.46PhePhe: 2.46 ± 0.93
1.23PheGly: 1.23 ± 0.528
1.64PheHis: 1.64 ± 0.857
3.28PheIle: 3.28 ± 1.145
1.64PheLys: 1.64 ± 0.654
3.69PheLeu: 3.69 ± 1.746
1.64PheMet: 1.64 ± 0.841
1.23PheAsn: 1.23 ± 0.643
4.1PhePro: 4.1 ± 0.669
1.23PheGln: 1.23 ± 0.643
1.23PheArg: 1.23 ± 0.644
2.87PheSer: 2.87 ± 1.261
2.05PheThr: 2.05 ± 1.456
2.05PheVal: 2.05 ± 1.071
0.0PheTrp: 0.0 ± 0.0
0.82PheTyr: 0.82 ± 0.598
0.0PheXaa: 0.0 ± 0.0
Gly
1.64GlyAla: 1.64 ± 0.654
2.46GlyCys: 2.46 ± 1.768
3.69GlyAsp: 3.69 ± 0.959
2.05GlyGlu: 2.05 ± 0.732
2.05GlyPhe: 2.05 ± 0.68
2.46GlyGly: 2.46 ± 1.46
1.23GlyHis: 1.23 ± 0.644
2.05GlyIle: 2.05 ± 0.885
2.46GlyLys: 2.46 ± 0.741
3.69GlyLeu: 3.69 ± 2.488
0.82GlyMet: 0.82 ± 0.428
2.46GlyAsn: 2.46 ± 2.063
1.64GlyPro: 1.64 ± 1.017
0.82GlyGln: 0.82 ± 0.428
0.82GlyArg: 0.82 ± 1.178
3.28GlySer: 3.28 ± 0.496
3.28GlyThr: 3.28 ± 1.426
2.05GlyVal: 2.05 ± 1.934
1.23GlyTrp: 1.23 ± 0.589
0.41GlyTyr: 0.41 ± 0.214
0.0GlyXaa: 0.0 ± 0.0
His
2.05HisAla: 2.05 ± 0.766
0.41HisCys: 0.41 ± 0.789
0.0HisAsp: 0.0 ± 0.0
1.23HisGlu: 1.23 ± 1.29
1.64HisPhe: 1.64 ± 0.549
2.87HisGly: 2.87 ± 1.885
2.46HisHis: 2.46 ± 1.012
1.23HisIle: 1.23 ± 0.528
2.87HisLys: 2.87 ± 0.867
4.51HisLeu: 4.51 ± 0.766
0.41HisMet: 0.41 ± 0.214
0.0HisAsn: 0.0 ± 0.0
1.23HisPro: 1.23 ± 0.575
2.46HisGln: 2.46 ± 0.914
0.41HisArg: 0.41 ± 0.214
3.28HisSer: 3.28 ± 1.963
1.23HisThr: 1.23 ± 0.643
1.23HisVal: 1.23 ± 0.644
0.0HisTrp: 0.0 ± 0.0
0.41HisTyr: 0.41 ± 0.945
0.0HisXaa: 0.0 ± 0.0
Ile
5.33IleAla: 5.33 ± 1.212
0.41IleCys: 0.41 ± 0.789
1.23IleAsp: 1.23 ± 0.643
2.05IleGlu: 2.05 ± 1.071
3.28IlePhe: 3.28 ± 1.582
1.64IleGly: 1.64 ± 0.876
1.64IleHis: 1.64 ± 0.876
3.69IleIle: 3.69 ± 1.583
4.51IleLys: 4.51 ± 1.223
5.33IleLeu: 5.33 ± 1.444
0.41IleMet: 0.41 ± 0.214
2.87IleAsn: 2.87 ± 0.588
3.28IlePro: 3.28 ± 1.145
3.69IleGln: 3.69 ± 0.995
2.87IleArg: 2.87 ± 0.903
2.87IleSer: 2.87 ± 1.499
4.1IleThr: 4.1 ± 2.35
2.87IleVal: 2.87 ± 1.499
0.41IleTrp: 0.41 ± 0.214
1.23IleTyr: 1.23 ± 0.644
0.0IleXaa: 0.0 ± 0.0
Lys
2.87LysAla: 2.87 ± 0.959
0.0LysCys: 0.0 ± 0.0
2.46LysAsp: 2.46 ± 1.285
2.46LysGlu: 2.46 ± 0.822
2.87LysPhe: 2.87 ± 0.903
2.87LysGly: 2.87 ± 0.959
1.64LysHis: 1.64 ± 0.654
3.28LysIle: 3.28 ± 0.704
2.87LysLys: 2.87 ± 1.226
10.66LysLeu: 10.66 ± 2.918
1.23LysMet: 1.23 ± 0.643
1.23LysAsn: 1.23 ± 0.643
2.87LysPro: 2.87 ± 1.105
3.28LysGln: 3.28 ± 0.704
3.69LysArg: 3.69 ± 1.22
4.1LysSer: 4.1 ± 0.906
3.28LysThr: 3.28 ± 1.714
3.69LysVal: 3.69 ± 0.959
0.82LysTrp: 0.82 ± 0.428
2.05LysTyr: 2.05 ± 1.608
0.0LysXaa: 0.0 ± 0.0
Leu
8.2LeuAla: 8.2 ± 2.65
2.46LeuCys: 2.46 ± 2.04
6.56LeuAsp: 6.56 ± 2.816
6.56LeuGlu: 6.56 ± 1.353
4.1LeuPhe: 4.1 ± 1.035
4.51LeuGly: 4.51 ± 1.055
2.87LeuHis: 2.87 ± 0.776
2.46LeuIle: 2.46 ± 0.783
8.61LeuLys: 8.61 ± 3.245
13.53LeuLeu: 13.53 ± 5.698
1.64LeuMet: 1.64 ± 0.707
3.69LeuAsn: 3.69 ± 0.837
7.38LeuPro: 7.38 ± 2.104
4.1LeuGln: 4.1 ± 0.906
4.51LeuArg: 4.51 ± 1.604
9.02LeuSer: 9.02 ± 2.152
9.02LeuThr: 9.02 ± 2.962
4.51LeuVal: 4.51 ± 0.901
0.82LeuTrp: 0.82 ± 0.589
3.69LeuTyr: 3.69 ± 1.415
0.0LeuXaa: 0.0 ± 0.0
Met
2.05MetAla: 2.05 ± 0.775
0.82MetCys: 0.82 ± 0.589
0.82MetAsp: 0.82 ± 0.589
0.82MetGlu: 0.82 ± 0.598
0.82MetPhe: 0.82 ± 0.428
0.82MetGly: 0.82 ± 0.428
1.64MetHis: 1.64 ± 0.857
0.82MetIle: 0.82 ± 0.428
0.82MetLys: 0.82 ± 0.428
2.87MetLeu: 2.87 ± 1.499
0.0MetMet: 0.0 ± 0.0
1.23MetAsn: 1.23 ± 0.575
0.41MetPro: 0.41 ± 0.789
1.64MetGln: 1.64 ± 0.698
2.46MetArg: 2.46 ± 1.285
0.82MetSer: 0.82 ± 0.428
0.82MetThr: 0.82 ± 0.428
0.0MetVal: 0.0 ± 0.0
0.41MetTrp: 0.41 ± 0.678
0.41MetTyr: 0.41 ± 0.678
0.0MetXaa: 0.0 ± 0.0
Asn
4.51AsnAla: 4.51 ± 1.888
2.05AsnCys: 2.05 ± 0.907
1.23AsnAsp: 1.23 ± 0.643
0.41AsnGlu: 0.41 ± 0.214
0.41AsnPhe: 0.41 ± 0.214
0.82AsnGly: 0.82 ± 1.345
2.87AsnHis: 2.87 ± 1.997
2.87AsnIle: 2.87 ± 0.712
2.05AsnLys: 2.05 ± 1.071
4.51AsnLeu: 4.51 ± 2.241
0.41AsnMet: 0.41 ± 0.214
1.23AsnAsn: 1.23 ± 0.643
2.87AsnPro: 2.87 ± 0.996
1.64AsnGln: 1.64 ± 0.638
3.28AsnArg: 3.28 ± 1.07
1.23AsnSer: 1.23 ± 0.815
2.87AsnThr: 2.87 ± 0.845
1.23AsnVal: 1.23 ± 0.589
0.0AsnTrp: 0.0 ± 0.0
2.05AsnTyr: 2.05 ± 1.314
0.0AsnXaa: 0.0 ± 0.0
Pro
7.38ProAla: 7.38 ± 3.9
0.82ProCys: 0.82 ± 0.598
3.28ProAsp: 3.28 ± 0.893
5.33ProGlu: 5.33 ± 1.743
1.64ProPhe: 1.64 ± 0.857
2.05ProGly: 2.05 ± 1.025
2.87ProHis: 2.87 ± 2.784
3.69ProIle: 3.69 ± 1.339
5.33ProLys: 5.33 ± 0.951
5.33ProLeu: 5.33 ± 0.973
1.23ProMet: 1.23 ± 0.575
0.82ProAsn: 0.82 ± 0.986
4.51ProPro: 4.51 ± 1.546
1.64ProGln: 1.64 ± 1.177
1.23ProArg: 1.23 ± 1.572
4.51ProSer: 4.51 ± 2.134
6.15ProThr: 6.15 ± 1.572
4.1ProVal: 4.1 ± 1.651
1.64ProTrp: 1.64 ± 1.007
2.87ProTyr: 2.87 ± 0.747
0.0ProXaa: 0.0 ± 0.0
Gln
2.05GlnAla: 2.05 ± 1.852
0.41GlnCys: 0.41 ± 0.674
2.46GlnAsp: 2.46 ± 1.285
2.05GlnGlu: 2.05 ± 0.645
1.64GlnPhe: 1.64 ± 1.195
1.23GlnGly: 1.23 ± 0.886
2.05GlnHis: 2.05 ± 1.598
2.87GlnIle: 2.87 ± 0.959
1.64GlnLys: 1.64 ± 0.549
4.1GlnLeu: 4.1 ± 0.918
1.23GlnMet: 1.23 ± 0.643
0.82GlnAsn: 0.82 ± 0.598
4.1GlnPro: 4.1 ± 0.908
3.28GlnGln: 3.28 ± 0.945
0.82GlnArg: 0.82 ± 1.356
2.46GlnSer: 2.46 ± 0.914
4.1GlnThr: 4.1 ± 1.079
2.46GlnVal: 2.46 ± 0.899
0.82GlnTrp: 0.82 ± 0.428
0.82GlnTyr: 0.82 ± 1.178
0.0GlnXaa: 0.0 ± 0.0
Arg
2.87ArgAla: 2.87 ± 1.039
0.0ArgCys: 0.0 ± 0.0
3.28ArgAsp: 3.28 ± 1.145
3.28ArgGlu: 3.28 ± 0.775
2.87ArgPhe: 2.87 ± 1.099
0.41ArgGly: 0.41 ± 0.214
0.41ArgHis: 0.41 ± 0.214
2.46ArgIle: 2.46 ± 0.899
2.46ArgLys: 2.46 ± 0.789
4.51ArgLeu: 4.51 ± 1.217
1.23ArgMet: 1.23 ± 0.589
3.28ArgAsn: 3.28 ± 0.863
3.28ArgPro: 3.28 ± 0.817
2.87ArgGln: 2.87 ± 2.447
2.87ArgArg: 2.87 ± 0.959
4.1ArgSer: 4.1 ± 1.332
2.46ArgThr: 2.46 ± 0.789
2.87ArgVal: 2.87 ± 1.648
0.41ArgTrp: 0.41 ± 0.674
2.05ArgTyr: 2.05 ± 0.775
0.0ArgXaa: 0.0 ± 0.0
Ser
4.1SerAla: 4.1 ± 1.086
2.05SerCys: 2.05 ± 0.766
3.69SerAsp: 3.69 ± 0.859
2.87SerGlu: 2.87 ± 1.048
3.69SerPhe: 3.69 ± 1.822
3.69SerGly: 3.69 ± 2.381
1.64SerHis: 1.64 ± 1.555
3.69SerIle: 3.69 ± 1.254
3.28SerLys: 3.28 ± 0.704
10.25SerLeu: 10.25 ± 3.921
0.41SerMet: 0.41 ± 0.214
3.28SerAsn: 3.28 ± 1.084
6.56SerPro: 6.56 ± 1.516
2.87SerGln: 2.87 ± 0.712
5.74SerArg: 5.74 ± 0.936
4.92SerSer: 4.92 ± 2.258
6.15SerThr: 6.15 ± 2.903
7.38SerVal: 7.38 ± 0.811
1.64SerTrp: 1.64 ± 0.857
2.46SerTyr: 2.46 ± 0.789
0.0SerXaa: 0.0 ± 0.0
Thr
7.38ThrAla: 7.38 ± 2.138
1.64ThrCys: 1.64 ± 0.847
2.05ThrAsp: 2.05 ± 0.567
2.46ThrGlu: 2.46 ± 1.285
2.87ThrPhe: 2.87 ± 1.499
2.87ThrGly: 2.87 ± 0.953
2.87ThrHis: 2.87 ± 0.959
2.87ThrIle: 2.87 ± 1.055
2.87ThrLys: 2.87 ± 1.048
7.79ThrLeu: 7.79 ± 2.714
2.05ThrMet: 2.05 ± 0.792
2.05ThrAsn: 2.05 ± 0.977
8.61ThrPro: 8.61 ± 2.858
2.05ThrGln: 2.05 ± 1.717
3.28ThrArg: 3.28 ± 0.496
8.2ThrSer: 8.2 ± 4.009
5.74ThrThr: 5.74 ± 2.605
2.87ThrVal: 2.87 ± 0.588
0.41ThrTrp: 0.41 ± 0.713
1.23ThrTyr: 1.23 ± 0.643
0.0ThrXaa: 0.0 ± 0.0
Val
2.46ValAla: 2.46 ± 1.63
1.23ValCys: 1.23 ± 1.139
2.87ValAsp: 2.87 ± 0.959
3.69ValGlu: 3.69 ± 1.928
3.28ValPhe: 3.28 ± 1.11
1.64ValGly: 1.64 ± 0.76
0.41ValHis: 0.41 ± 0.214
3.69ValIle: 3.69 ± 3.101
2.46ValLys: 2.46 ± 0.822
5.74ValLeu: 5.74 ± 1.63
1.23ValMet: 1.23 ± 0.643
2.87ValAsn: 2.87 ± 1.048
2.05ValPro: 2.05 ± 0.567
3.28ValGln: 3.28 ± 0.836
3.69ValArg: 3.69 ± 1.178
3.28ValSer: 3.28 ± 1.314
3.69ValThr: 3.69 ± 1.178
5.74ValVal: 5.74 ± 3.179
0.41ValTrp: 0.41 ± 0.678
2.46ValTyr: 2.46 ± 0.715
0.0ValXaa: 0.0 ± 0.0
Trp
1.64TrpAla: 1.64 ± 0.654
0.0TrpCys: 0.0 ± 0.0
0.82TrpAsp: 0.82 ± 0.598
0.82TrpGlu: 0.82 ± 0.428
0.0TrpPhe: 0.0 ± 0.0
0.41TrpGly: 0.41 ± 0.713
0.41TrpHis: 0.41 ± 0.214
0.0TrpIle: 0.0 ± 0.0
0.82TrpLys: 0.82 ± 0.428
1.23TrpLeu: 1.23 ± 0.589
0.82TrpMet: 0.82 ± 0.428
0.82TrpAsn: 0.82 ± 1.293
0.0TrpPro: 0.0 ± 0.0
0.82TrpGln: 0.82 ± 0.428
0.41TrpArg: 0.41 ± 0.713
1.64TrpSer: 1.64 ± 0.847
0.41TrpThr: 0.41 ± 0.214
1.64TrpVal: 1.64 ± 0.857
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.92TyrAla: 4.92 ± 0.943
1.23TyrCys: 1.23 ± 0.644
1.23TyrAsp: 1.23 ± 0.643
1.23TyrGlu: 1.23 ± 0.886
2.05TyrPhe: 2.05 ± 0.68
0.82TyrGly: 0.82 ± 0.598
0.82TyrHis: 0.82 ± 0.428
2.46TyrIle: 2.46 ± 0.789
1.23TyrLys: 1.23 ± 0.644
2.46TyrLeu: 2.46 ± 1.335
1.23TyrMet: 1.23 ± 0.551
0.82TyrAsn: 0.82 ± 0.428
0.41TyrPro: 0.41 ± 0.214
0.41TyrGln: 0.41 ± 0.214
1.23TyrArg: 1.23 ± 1.139
3.28TyrSer: 3.28 ± 2.033
2.87TyrThr: 2.87 ± 0.722
0.82TyrVal: 0.82 ± 1.293
0.82TyrTrp: 0.82 ± 0.428
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2440 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski