Amino acid dipepetide frequency for Soybean cyst nematode socyvirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.067AlaAla: 9.067 ± 3.488
0.292AlaCys: 0.292 ± 0.381
4.095AlaAsp: 4.095 ± 1.665
3.802AlaGlu: 3.802 ± 0.635
1.755AlaPhe: 1.755 ± 1.483
7.897AlaGly: 7.897 ± 2.45
1.462AlaHis: 1.462 ± 0.661
4.68AlaIle: 4.68 ± 0.906
4.387AlaLys: 4.387 ± 1.809
8.774AlaLeu: 8.774 ± 1.042
2.632AlaMet: 2.632 ± 0.255
2.925AlaAsn: 2.925 ± 1.607
4.387AlaPro: 4.387 ± 1.566
4.387AlaGln: 4.387 ± 0.454
4.972AlaArg: 4.972 ± 1.282
5.557AlaSer: 5.557 ± 0.622
5.85AlaThr: 5.85 ± 0.906
4.68AlaVal: 4.68 ± 1.97
2.047AlaTrp: 2.047 ± 1.017
1.755AlaTyr: 1.755 ± 0.733
0.0AlaXaa: 0.0 ± 0.0
Cys
1.17CysAla: 1.17 ± 0.616
0.877CysCys: 0.877 ± 0.59
1.17CysAsp: 1.17 ± 0.673
0.292CysGlu: 0.292 ± 0.16
0.877CysPhe: 0.877 ± 0.309
1.17CysGly: 1.17 ± 0.521
0.877CysHis: 0.877 ± 0.48
0.585CysIle: 0.585 ± 0.308
0.585CysLys: 0.585 ± 0.308
2.925CysLeu: 2.925 ± 0.557
0.585CysMet: 0.585 ± 0.536
0.585CysAsn: 0.585 ± 0.308
2.34CysPro: 2.34 ± 0.932
0.0CysGln: 0.0 ± 0.0
0.585CysArg: 0.585 ± 0.32
1.462CysSer: 1.462 ± 0.596
0.585CysThr: 0.585 ± 0.308
1.17CysVal: 1.17 ± 0.64
0.585CysTrp: 0.585 ± 0.308
0.585CysTyr: 0.585 ± 0.308
0.0CysXaa: 0.0 ± 0.0
Asp
2.34AspAla: 2.34 ± 0.769
0.292AspCys: 0.292 ± 0.381
2.632AspAsp: 2.632 ± 1.532
4.68AspGlu: 4.68 ± 0.81
1.755AspPhe: 1.755 ± 0.709
3.217AspGly: 3.217 ± 0.764
1.462AspHis: 1.462 ± 0.379
4.095AspIle: 4.095 ± 1.065
2.632AspLys: 2.632 ± 0.618
5.85AspLeu: 5.85 ± 1.277
1.17AspMet: 1.17 ± 1.137
2.34AspAsn: 2.34 ± 1.232
8.482AspPro: 8.482 ± 2.253
0.877AspGln: 0.877 ± 0.309
3.802AspArg: 3.802 ± 1.459
1.755AspSer: 1.755 ± 0.379
4.387AspThr: 4.387 ± 1.342
2.047AspVal: 2.047 ± 1.121
0.292AspTrp: 0.292 ± 0.381
2.047AspTyr: 2.047 ± 1.121
0.0AspXaa: 0.0 ± 0.0
Glu
5.265GluAla: 5.265 ± 1.28
0.877GluCys: 0.877 ± 0.309
3.217GluAsp: 3.217 ± 0.442
3.802GluGlu: 3.802 ± 1.095
2.34GluPhe: 2.34 ± 0.613
4.68GluGly: 4.68 ± 0.641
1.17GluHis: 1.17 ± 1.137
1.755GluIle: 1.755 ± 0.924
2.047GluLys: 2.047 ± 0.871
5.85GluLeu: 5.85 ± 1.174
1.462GluMet: 1.462 ± 1.006
1.17GluAsn: 1.17 ± 0.658
2.047GluPro: 2.047 ± 0.702
1.462GluGln: 1.462 ± 0.482
2.632GluArg: 2.632 ± 0.934
3.802GluSer: 3.802 ± 0.471
2.34GluThr: 2.34 ± 0.613
3.802GluVal: 3.802 ± 0.477
0.585GluTrp: 0.585 ± 0.32
2.047GluTyr: 2.047 ± 0.679
0.0GluXaa: 0.0 ± 0.0
Phe
2.632PheAla: 2.632 ± 1.303
0.585PheCys: 0.585 ± 0.32
2.047PheAsp: 2.047 ± 0.518
1.17PheGlu: 1.17 ± 0.64
0.877PhePhe: 0.877 ± 0.48
1.17PheGly: 1.17 ± 0.866
1.17PheHis: 1.17 ± 0.384
1.755PheIle: 1.755 ± 0.987
2.34PheLys: 2.34 ± 0.769
3.51PheLeu: 3.51 ± 0.919
1.17PheMet: 1.17 ± 0.522
1.17PheAsn: 1.17 ± 0.45
1.17PhePro: 1.17 ± 0.45
1.17PheGln: 1.17 ± 0.422
2.632PheArg: 2.632 ± 0.76
2.632PheSer: 2.632 ± 1.085
1.17PheThr: 1.17 ± 0.284
0.292PheVal: 0.292 ± 0.16
0.292PheTrp: 0.292 ± 0.16
0.585PheTyr: 0.585 ± 0.32
0.0PheXaa: 0.0 ± 0.0
Gly
3.217GlyAla: 3.217 ± 1.273
2.047GlyCys: 2.047 ± 0.638
3.217GlyAsp: 3.217 ± 0.344
2.34GlyGlu: 2.34 ± 0.566
2.632GlyPhe: 2.632 ± 0.806
4.387GlyGly: 4.387 ± 2.262
0.877GlyHis: 0.877 ± 0.36
3.51GlyIle: 3.51 ± 1.153
2.047GlyLys: 2.047 ± 1.139
5.265GlyLeu: 5.265 ± 1.188
1.17GlyMet: 1.17 ± 0.401
4.095GlyAsn: 4.095 ± 0.802
3.51GlyPro: 3.51 ± 0.893
1.17GlyGln: 1.17 ± 0.466
5.85GlyArg: 5.85 ± 1.637
5.265GlySer: 5.265 ± 2.035
3.51GlyThr: 3.51 ± 1.884
2.632GlyVal: 2.632 ± 0.737
0.877GlyTrp: 0.877 ± 0.309
2.632GlyTyr: 2.632 ± 0.932
0.0GlyXaa: 0.0 ± 0.0
His
2.047HisAla: 2.047 ± 0.993
0.585HisCys: 0.585 ± 0.536
0.877HisAsp: 0.877 ± 0.48
1.755HisGlu: 1.755 ± 0.493
1.462HisPhe: 1.462 ± 0.482
0.877HisGly: 0.877 ± 0.419
0.585HisHis: 0.585 ± 0.329
0.585HisIle: 0.585 ± 0.308
0.877HisLys: 0.877 ± 0.48
4.387HisLeu: 4.387 ± 0.624
0.877HisMet: 0.877 ± 0.558
0.292HisAsn: 0.292 ± 0.16
1.755HisPro: 1.755 ± 0.349
1.462HisGln: 1.462 ± 0.993
1.462HisArg: 1.462 ± 0.8
0.585HisSer: 0.585 ± 0.32
0.585HisThr: 0.585 ± 0.308
1.755HisVal: 1.755 ± 0.924
0.585HisTrp: 0.585 ± 0.473
0.877HisTyr: 0.877 ± 0.36
0.0HisXaa: 0.0 ± 0.0
Ile
5.557IleAla: 5.557 ± 1.519
0.877IleCys: 0.877 ± 0.368
3.802IleAsp: 3.802 ± 0.244
2.047IleGlu: 2.047 ± 0.854
1.17IlePhe: 1.17 ± 0.45
3.51IleGly: 3.51 ± 1.492
2.047IleHis: 2.047 ± 0.55
2.632IleIle: 2.632 ± 0.879
1.462IleLys: 1.462 ± 0.501
5.85IleLeu: 5.85 ± 2.479
1.17IleMet: 1.17 ± 0.284
1.755IleAsn: 1.755 ± 0.349
4.387IlePro: 4.387 ± 0.994
1.17IleGln: 1.17 ± 0.284
3.51IleArg: 3.51 ± 0.646
3.802IleSer: 3.802 ± 1.756
2.925IleThr: 2.925 ± 0.74
3.51IleVal: 3.51 ± 0.621
1.17IleTrp: 1.17 ± 0.384
1.17IleTyr: 1.17 ± 0.384
0.0IleXaa: 0.0 ± 0.0
Lys
3.217LysAla: 3.217 ± 0.344
0.585LysCys: 0.585 ± 0.32
2.925LysAsp: 2.925 ± 0.675
2.34LysGlu: 2.34 ± 0.569
1.17LysPhe: 1.17 ± 0.64
2.047LysGly: 2.047 ± 0.257
1.17LysHis: 1.17 ± 0.284
4.095LysIle: 4.095 ± 0.762
3.51LysLys: 3.51 ± 0.517
4.095LysLeu: 4.095 ± 1.328
2.925LysMet: 2.925 ± 0.418
1.755LysAsn: 1.755 ± 0.777
2.34LysPro: 2.34 ± 1.003
0.877LysGln: 0.877 ± 0.309
2.047LysArg: 2.047 ± 0.897
2.047LysSer: 2.047 ± 1.139
3.51LysThr: 3.51 ± 0.774
4.387LysVal: 4.387 ± 2.094
1.17LysTrp: 1.17 ± 0.384
0.585LysTyr: 0.585 ± 0.32
0.0LysXaa: 0.0 ± 0.0
Leu
11.699LeuAla: 11.699 ± 3.202
2.34LeuCys: 2.34 ± 0.769
5.557LeuAsp: 5.557 ± 1.253
4.095LeuGlu: 4.095 ± 1.364
4.68LeuPhe: 4.68 ± 1.034
4.68LeuGly: 4.68 ± 1.597
2.632LeuHis: 2.632 ± 0.255
5.265LeuIle: 5.265 ± 1.36
5.557LeuLys: 5.557 ± 1.678
11.699LeuLeu: 11.699 ± 1.528
2.632LeuMet: 2.632 ± 0.755
2.34LeuAsn: 2.34 ± 0.844
6.727LeuPro: 6.727 ± 1.011
4.387LeuGln: 4.387 ± 0.818
6.142LeuArg: 6.142 ± 1.998
6.142LeuSer: 6.142 ± 2.136
8.19LeuThr: 8.19 ± 1.352
6.142LeuVal: 6.142 ± 1.327
1.755LeuTrp: 1.755 ± 0.493
4.68LeuTyr: 4.68 ± 1.635
0.0LeuXaa: 0.0 ± 0.0
Met
2.925MetAla: 2.925 ± 1.371
0.585MetCys: 0.585 ± 0.536
2.34MetAsp: 2.34 ± 0.613
1.755MetGlu: 1.755 ± 0.467
0.585MetPhe: 0.585 ± 0.308
0.877MetGly: 0.877 ± 0.419
0.585MetHis: 0.585 ± 0.32
1.17MetIle: 1.17 ± 0.45
2.047MetLys: 2.047 ± 1.412
3.802MetLeu: 3.802 ± 1.378
1.17MetMet: 1.17 ± 0.772
0.877MetAsn: 0.877 ± 0.419
0.585MetPro: 0.585 ± 0.308
0.585MetGln: 0.585 ± 0.329
1.17MetArg: 1.17 ± 0.64
2.632MetSer: 2.632 ± 1.039
3.802MetThr: 3.802 ± 0.888
1.755MetVal: 1.755 ± 0.937
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.925AsnAla: 2.925 ± 0.803
0.585AsnCys: 0.585 ± 0.308
2.632AsnAsp: 2.632 ± 0.452
1.755AsnGlu: 1.755 ± 0.72
0.585AsnPhe: 0.585 ± 0.329
1.17AsnGly: 1.17 ± 0.866
0.585AsnHis: 0.585 ± 0.32
1.755AsnIle: 1.755 ± 0.888
1.462AsnLys: 1.462 ± 0.482
4.095AsnLeu: 4.095 ± 0.377
0.292AsnMet: 0.292 ± 0.381
0.877AsnAsn: 0.877 ± 0.36
2.925AsnPro: 2.925 ± 2.062
1.462AsnGln: 1.462 ± 0.482
2.34AsnArg: 2.34 ± 0.613
1.462AsnSer: 1.462 ± 1.505
0.585AsnThr: 0.585 ± 0.329
2.34AsnVal: 2.34 ± 0.2
1.17AsnTrp: 1.17 ± 0.616
0.877AsnTyr: 0.877 ± 0.48
0.0AsnXaa: 0.0 ± 0.0
Pro
3.217ProAla: 3.217 ± 0.775
1.462ProCys: 1.462 ± 0.501
5.265ProAsp: 5.265 ± 2.035
5.265ProGlu: 5.265 ± 0.999
0.877ProPhe: 0.877 ± 0.419
2.632ProGly: 2.632 ± 0.593
0.292ProHis: 0.292 ± 0.16
2.632ProIle: 2.632 ± 0.98
2.632ProLys: 2.632 ± 0.509
5.265ProLeu: 5.265 ± 0.868
1.755ProMet: 1.755 ± 0.683
1.755ProAsn: 1.755 ± 1.42
7.02ProPro: 7.02 ± 5.325
1.462ProGln: 1.462 ± 1.235
3.802ProArg: 3.802 ± 1.466
6.142ProSer: 6.142 ± 3.165
7.02ProThr: 7.02 ± 1.177
3.51ProVal: 3.51 ± 0.691
1.17ProTrp: 1.17 ± 0.58
1.755ProTyr: 1.755 ± 0.709
0.0ProXaa: 0.0 ± 0.0
Gln
4.387GlnAla: 4.387 ± 1.351
0.585GlnCys: 0.585 ± 0.308
1.17GlnAsp: 1.17 ± 0.466
1.17GlnGlu: 1.17 ± 0.466
0.585GlnPhe: 0.585 ± 0.32
2.047GlnGly: 2.047 ± 0.854
1.17GlnHis: 1.17 ± 0.616
1.17GlnIle: 1.17 ± 1.525
2.632GlnLys: 2.632 ± 0.928
6.142GlnLeu: 6.142 ± 0.689
1.462GlnMet: 1.462 ± 0.279
1.462GlnAsn: 1.462 ± 0.879
1.17GlnPro: 1.17 ± 0.947
0.877GlnGln: 0.877 ± 0.48
1.462GlnArg: 1.462 ± 0.482
2.34GlnSer: 2.34 ± 0.2
3.217GlnThr: 3.217 ± 1.755
2.34GlnVal: 2.34 ± 0.608
0.585GlnTrp: 0.585 ± 0.32
1.17GlnTyr: 1.17 ± 0.284
0.0GlnXaa: 0.0 ± 0.0
Arg
4.972ArgAla: 4.972 ± 0.459
0.585ArgCys: 0.585 ± 0.32
2.632ArgAsp: 2.632 ± 0.808
2.632ArgGlu: 2.632 ± 0.602
2.925ArgPhe: 2.925 ± 1.31
4.68ArgGly: 4.68 ± 0.4
2.34ArgHis: 2.34 ± 0.535
2.34ArgIle: 2.34 ± 0.814
1.17ArgLys: 1.17 ± 0.64
8.774ArgLeu: 8.774 ± 1.503
1.17ArgMet: 1.17 ± 0.384
0.877ArgAsn: 0.877 ± 0.36
2.925ArgPro: 2.925 ± 0.667
4.972ArgGln: 4.972 ± 1.461
4.68ArgArg: 4.68 ± 0.793
4.095ArgSer: 4.095 ± 1.742
5.557ArgThr: 5.557 ± 1.136
2.925ArgVal: 2.925 ± 1.601
0.292ArgTrp: 0.292 ± 0.16
0.877ArgTyr: 0.877 ± 0.782
0.0ArgXaa: 0.0 ± 0.0
Ser
4.68SerAla: 4.68 ± 1.87
1.755SerCys: 1.755 ± 0.619
4.387SerAsp: 4.387 ± 1.612
3.51SerGlu: 3.51 ± 1.017
1.17SerPhe: 1.17 ± 0.45
5.85SerGly: 5.85 ± 0.782
1.755SerHis: 1.755 ± 0.619
4.972SerIle: 4.972 ± 0.762
1.462SerLys: 1.462 ± 0.501
7.02SerLeu: 7.02 ± 1.541
0.877SerMet: 0.877 ± 0.309
2.047SerAsn: 2.047 ± 0.926
2.632SerPro: 2.632 ± 2.638
3.217SerGln: 3.217 ± 1.629
2.925SerArg: 2.925 ± 1.376
3.51SerSer: 3.51 ± 0.646
6.142SerThr: 6.142 ± 1.452
3.51SerVal: 3.51 ± 1.274
1.462SerTrp: 1.462 ± 0.568
1.17SerTyr: 1.17 ± 0.466
0.0SerXaa: 0.0 ± 0.0
Thr
6.435ThrAla: 6.435 ± 2.84
2.047ThrCys: 2.047 ± 0.679
3.802ThrAsp: 3.802 ± 0.955
3.51ThrGlu: 3.51 ± 1.426
1.462ThrPhe: 1.462 ± 0.469
3.217ThrGly: 3.217 ± 1.422
2.632ThrHis: 2.632 ± 0.76
2.925ThrIle: 2.925 ± 0.744
3.217ThrLys: 3.217 ± 0.617
4.972ThrLeu: 4.972 ± 0.459
3.51ThrMet: 3.51 ± 0.252
2.925ThrAsn: 2.925 ± 0.474
3.51ThrPro: 3.51 ± 1.738
2.632ThrGln: 2.632 ± 0.765
5.557ThrArg: 5.557 ± 2.324
5.557ThrSer: 5.557 ± 1.451
3.802ThrThr: 3.802 ± 1.649
7.312ThrVal: 7.312 ± 1.285
0.585ThrTrp: 0.585 ± 0.32
2.047ThrTyr: 2.047 ± 0.891
0.0ThrXaa: 0.0 ± 0.0
Val
5.85ValAla: 5.85 ± 0.782
1.17ValCys: 1.17 ± 0.616
2.632ValAsp: 2.632 ± 0.509
4.095ValGlu: 4.095 ± 0.327
1.755ValPhe: 1.755 ± 0.637
2.925ValGly: 2.925 ± 1.351
0.585ValHis: 0.585 ± 1.167
4.68ValIle: 4.68 ± 1.507
4.68ValLys: 4.68 ± 0.499
4.387ValLeu: 4.387 ± 0.854
2.34ValMet: 2.34 ± 0.932
1.17ValAsn: 1.17 ± 0.45
3.217ValPro: 3.217 ± 1.117
2.047ValGln: 2.047 ± 0.679
2.632ValArg: 2.632 ± 0.737
3.51ValSer: 3.51 ± 1.219
3.51ValThr: 3.51 ± 0.55
3.802ValVal: 3.802 ± 1.174
1.17ValTrp: 1.17 ± 0.616
2.925ValTyr: 2.925 ± 0.744
0.0ValXaa: 0.0 ± 0.0
Trp
1.462TrpAla: 1.462 ± 0.853
0.292TrpCys: 0.292 ± 0.16
0.585TrpAsp: 0.585 ± 0.491
1.462TrpGlu: 1.462 ± 0.501
0.292TrpPhe: 0.292 ± 0.16
0.877TrpGly: 0.877 ± 0.48
0.292TrpHis: 0.292 ± 0.16
1.755TrpIle: 1.755 ± 0.924
1.462TrpLys: 1.462 ± 0.977
0.585TrpLeu: 0.585 ± 0.32
0.0TrpMet: 0.0 ± 0.0
0.585TrpAsn: 0.585 ± 0.32
1.755TrpPro: 1.755 ± 0.637
0.585TrpGln: 0.585 ± 0.32
0.585TrpArg: 0.585 ± 0.536
0.877TrpSer: 0.877 ± 0.585
2.34TrpThr: 2.34 ± 0.801
0.877TrpVal: 0.877 ± 0.368
0.292TrpTrp: 0.292 ± 0.16
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.34TyrAla: 2.34 ± 0.932
0.585TyrCys: 0.585 ± 0.32
1.17TyrAsp: 1.17 ± 0.384
0.877TyrGlu: 0.877 ± 0.309
0.585TyrPhe: 0.585 ± 0.329
2.34TyrGly: 2.34 ± 0.826
0.585TyrHis: 0.585 ± 0.308
1.17TyrIle: 1.17 ± 0.284
0.585TyrLys: 0.585 ± 0.536
4.095TyrLeu: 4.095 ± 1.057
0.877TyrMet: 0.877 ± 0.48
0.877TyrAsn: 0.877 ± 0.48
2.047TyrPro: 2.047 ± 0.679
2.34TyrGln: 2.34 ± 1.281
2.632TyrArg: 2.632 ± 0.509
0.877TyrSer: 0.877 ± 0.36
2.632TyrThr: 2.632 ± 0.644
0.292TyrVal: 0.292 ± 0.16
0.877TyrTrp: 0.877 ± 0.666
1.17TyrTyr: 1.17 ± 0.64
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3420 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski