Amino acid dipepetide frequency for Spodoptera litura (Asian cotton leafworm)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
23.736AlaAla: 23.736 ± 2.059
0.61AlaCys: 0.61 ± 0.103
5.408AlaAsp: 5.408 ± 0.333
3.386AlaGlu: 3.386 ± 0.344
1.942AlaPhe: 1.942 ± 0.178
5.922AlaGly: 5.922 ± 0.586
6.516AlaHis: 6.516 ± 0.834
2.873AlaIle: 2.873 ± 0.238
4.365AlaLys: 4.365 ± 0.402
5.713AlaLeu: 5.713 ± 0.392
0.53AlaMet: 0.53 ± 0.097
2.728AlaAsn: 2.728 ± 0.285
21.296AlaPro: 21.296 ± 1.724
4.67AlaGln: 4.67 ± 0.467
3.948AlaArg: 3.948 ± 0.386
5.28AlaSer: 5.28 ± 0.332
3.579AlaThr: 3.579 ± 0.317
11.635AlaVal: 11.635 ± 0.796
0.481AlaTrp: 0.481 ± 0.115
7.318AlaTyr: 7.318 ± 0.666
0.0AlaXaa: 0.0 ± 0.0
Cys
0.931CysAla: 0.931 ± 0.101
0.048CysCys: 0.048 ± 0.027
0.786CysAsp: 0.786 ± 0.207
0.289CysGlu: 0.289 ± 0.097
0.16CysPhe: 0.16 ± 0.049
0.546CysGly: 0.546 ± 0.114
0.08CysHis: 0.08 ± 0.036
0.257CysIle: 0.257 ± 0.066
0.321CysLys: 0.321 ± 0.074
0.722CysLeu: 0.722 ± 0.101
0.128CysMet: 0.128 ± 0.049
0.241CysAsn: 0.241 ± 0.087
0.722CysPro: 0.722 ± 0.2
0.562CysGln: 0.562 ± 0.109
0.112CysArg: 0.112 ± 0.042
0.449CysSer: 0.449 ± 0.087
0.193CysThr: 0.193 ± 0.066
0.754CysVal: 0.754 ± 0.113
0.08CysTrp: 0.08 ± 0.036
0.032CysTyr: 0.032 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
2.68AspAla: 2.68 ± 0.246
0.546AspCys: 0.546 ± 0.124
3.948AspAsp: 3.948 ± 0.343
3.386AspGlu: 3.386 ± 0.441
1.541AspPhe: 1.541 ± 0.161
8.105AspGly: 8.105 ± 0.496
2.889AspHis: 2.889 ± 0.272
1.252AspIle: 1.252 ± 0.166
2.792AspLys: 2.792 ± 0.242
1.412AspLeu: 1.412 ± 0.196
0.144AspMet: 0.144 ± 0.044
2.102AspAsn: 2.102 ± 0.214
3.178AspPro: 3.178 ± 0.243
1.348AspGln: 1.348 ± 0.169
1.621AspArg: 1.621 ± 0.311
2.167AspSer: 2.167 ± 0.205
1.46AspThr: 1.46 ± 0.155
3.162AspVal: 3.162 ± 0.234
0.289AspTrp: 0.289 ± 0.071
2.776AspTyr: 2.776 ± 0.312
0.0AspXaa: 0.0 ± 0.0
Glu
4.092GluAla: 4.092 ± 0.305
0.257GluCys: 0.257 ± 0.1
2.857GluAsp: 2.857 ± 0.349
4.59GluGlu: 4.59 ± 0.439
1.476GluPhe: 1.476 ± 0.171
2.359GluGly: 2.359 ± 0.195
2.664GluHis: 2.664 ± 0.292
1.717GluIle: 1.717 ± 0.252
3.884GluLys: 3.884 ± 0.511
1.525GluLeu: 1.525 ± 0.211
0.401GluMet: 0.401 ± 0.088
2.792GluAsn: 2.792 ± 0.279
3.643GluPro: 3.643 ± 0.288
2.857GluGln: 2.857 ± 0.33
1.3GluArg: 1.3 ± 0.183
2.857GluSer: 2.857 ± 0.205
2.68GluThr: 2.68 ± 0.242
3.162GluVal: 3.162 ± 0.341
0.048GluTrp: 0.048 ± 0.025
4.012GluTyr: 4.012 ± 0.358
0.0GluXaa: 0.0 ± 0.0
Phe
2.696PheAla: 2.696 ± 0.22
0.16PheCys: 0.16 ± 0.051
1.332PheAsp: 1.332 ± 0.185
1.3PheGlu: 1.3 ± 0.169
0.722PhePhe: 0.722 ± 0.102
2.937PheGly: 2.937 ± 0.311
0.883PheHis: 0.883 ± 0.117
1.204PheIle: 1.204 ± 0.175
1.476PheLys: 1.476 ± 0.165
1.412PheLeu: 1.412 ± 0.167
0.177PheMet: 0.177 ± 0.053
2.118PheAsn: 2.118 ± 0.177
1.188PhePro: 1.188 ± 0.237
1.396PheGln: 1.396 ± 0.194
1.236PheArg: 1.236 ± 0.17
2.825PheSer: 2.825 ± 0.195
0.931PheThr: 0.931 ± 0.143
1.942PheVal: 1.942 ± 0.159
0.048PheTrp: 0.048 ± 0.031
0.899PheTyr: 0.899 ± 0.136
0.0PheXaa: 0.0 ± 0.0
Gly
6.933GlyAla: 6.933 ± 0.82
0.369GlyCys: 0.369 ± 0.104
5.36GlyAsp: 5.36 ± 0.355
2.199GlyGlu: 2.199 ± 0.219
4.799GlyPhe: 4.799 ± 0.346
11.812GlyGly: 11.812 ± 1.793
6.5GlyHis: 6.5 ± 0.706
2.937GlyIle: 2.937 ± 0.371
2.391GlyLys: 2.391 ± 0.207
4.301GlyLeu: 4.301 ± 0.528
1.155GlyMet: 1.155 ± 0.144
2.295GlyAsn: 2.295 ± 0.275
3.707GlyPro: 3.707 ± 0.55
2.616GlyGln: 2.616 ± 0.301
1.364GlyArg: 1.364 ± 0.175
6.676GlySer: 6.676 ± 0.567
2.712GlyThr: 2.712 ± 0.217
3.9GlyVal: 3.9 ± 0.398
0.851GlyTrp: 0.851 ± 0.213
7.703GlyTyr: 7.703 ± 0.753
0.0GlyXaa: 0.0 ± 0.0
His
5.745HisAla: 5.745 ± 0.615
0.177HisCys: 0.177 ± 0.064
2.52HisAsp: 2.52 ± 0.256
4.429HisGlu: 4.429 ± 0.556
0.674HisPhe: 0.674 ± 0.103
6.435HisGly: 6.435 ± 0.724
7.607HisHis: 7.607 ± 1.031
1.3HisIle: 1.3 ± 0.161
2.054HisLys: 2.054 ± 0.255
1.733HisLeu: 1.733 ± 0.202
0.802HisMet: 0.802 ± 0.103
1.316HisAsn: 1.316 ± 0.157
3.194HisPro: 3.194 ± 0.271
1.621HisGln: 1.621 ± 0.223
0.915HisArg: 0.915 ± 0.119
3.354HisSer: 3.354 ± 0.477
1.91HisThr: 1.91 ± 0.192
3.531HisVal: 3.531 ± 0.368
0.16HisTrp: 0.16 ± 0.056
3.178HisTyr: 3.178 ± 0.307
0.0HisXaa: 0.0 ± 0.0
Ile
4.622IleAla: 4.622 ± 0.391
0.369IleCys: 0.369 ± 0.079
1.38IleAsp: 1.38 ± 0.18
1.605IleGlu: 1.605 ± 0.163
1.027IlePhe: 1.027 ± 0.14
2.118IleGly: 2.118 ± 0.342
1.172IleHis: 1.172 ± 0.145
1.958IleIle: 1.958 ± 0.197
2.263IleLys: 2.263 ± 0.225
2.648IleLeu: 2.648 ± 0.22
0.353IleMet: 0.353 ± 0.08
1.412IleAsn: 1.412 ± 0.182
3.129IlePro: 3.129 ± 0.288
1.476IleGln: 1.476 ± 0.21
1.46IleArg: 1.46 ± 0.274
3.162IleSer: 3.162 ± 0.276
1.765IleThr: 1.765 ± 0.228
4.429IleVal: 4.429 ± 0.31
0.032IleTrp: 0.032 ± 0.021
0.931IleTyr: 0.931 ± 0.141
0.0IleXaa: 0.0 ± 0.0
Lys
3.37LysAla: 3.37 ± 0.208
0.337LysCys: 0.337 ± 0.106
1.476LysAsp: 1.476 ± 0.177
2.375LysGlu: 2.375 ± 0.22
1.316LysPhe: 1.316 ± 0.136
2.536LysGly: 2.536 ± 0.24
2.391LysHis: 2.391 ± 0.294
2.375LysIle: 2.375 ± 0.199
3.755LysLys: 3.755 ± 0.348
2.279LysLeu: 2.279 ± 0.221
0.514LysMet: 0.514 ± 0.094
1.412LysAsn: 1.412 ± 0.179
3.563LysPro: 3.563 ± 0.432
1.942LysGln: 1.942 ± 0.18
1.781LysArg: 1.781 ± 0.199
3.242LysSer: 3.242 ± 0.275
2.857LysThr: 2.857 ± 0.259
5.681LysVal: 5.681 ± 0.623
0.16LysTrp: 0.16 ± 0.053
3.643LysTyr: 3.643 ± 0.282
0.0LysXaa: 0.0 ± 0.0
Leu
6.644LeuAla: 6.644 ± 0.552
1.22LeuCys: 1.22 ± 0.138
2.118LeuAsp: 2.118 ± 0.199
2.022LeuGlu: 2.022 ± 0.239
1.428LeuPhe: 1.428 ± 0.173
3.739LeuGly: 3.739 ± 0.538
1.926LeuHis: 1.926 ± 0.206
2.134LeuIle: 2.134 ± 0.191
2.279LeuLys: 2.279 ± 0.21
4.124LeuLeu: 4.124 ± 0.253
0.417LeuMet: 0.417 ± 0.082
1.509LeuAsn: 1.509 ± 0.223
3.499LeuPro: 3.499 ± 0.317
1.685LeuGln: 1.685 ± 0.203
1.653LeuArg: 1.653 ± 0.189
3.82LeuSer: 3.82 ± 0.48
2.022LeuThr: 2.022 ± 0.208
4.478LeuVal: 4.478 ± 0.285
0.144LeuTrp: 0.144 ± 0.048
1.541LeuTyr: 1.541 ± 0.158
0.0LeuXaa: 0.0 ± 0.0
Met
0.754MetAla: 0.754 ± 0.1
0.209MetCys: 0.209 ± 0.061
0.273MetAsp: 0.273 ± 0.068
0.305MetGlu: 0.305 ± 0.098
1.091MetPhe: 1.091 ± 0.12
0.273MetGly: 0.273 ± 0.066
0.144MetHis: 0.144 ± 0.051
0.433MetIle: 0.433 ± 0.08
1.155MetLys: 1.155 ± 0.137
0.626MetLeu: 0.626 ± 0.118
0.337MetMet: 0.337 ± 0.181
0.385MetAsn: 0.385 ± 0.07
0.305MetPro: 0.305 ± 0.076
0.385MetGln: 0.385 ± 0.084
0.401MetArg: 0.401 ± 0.089
0.241MetSer: 0.241 ± 0.066
0.321MetThr: 0.321 ± 0.08
0.465MetVal: 0.465 ± 0.088
0.096MetTrp: 0.096 ± 0.036
0.546MetTyr: 0.546 ± 0.088
0.0MetXaa: 0.0 ± 0.0
Asn
4.317AsnAla: 4.317 ± 0.391
0.321AsnCys: 0.321 ± 0.096
1.605AsnAsp: 1.605 ± 0.229
1.765AsnGlu: 1.765 ± 0.209
1.027AsnPhe: 1.027 ± 0.159
5.184AsnGly: 5.184 ± 0.484
0.722AsnHis: 0.722 ± 0.122
1.765AsnIle: 1.765 ± 0.215
1.685AsnLys: 1.685 ± 0.21
1.669AsnLeu: 1.669 ± 0.236
0.385AsnMet: 0.385 ± 0.087
2.455AsnAsn: 2.455 ± 0.385
1.974AsnPro: 1.974 ± 0.2
1.509AsnGln: 1.509 ± 0.221
1.332AsnArg: 1.332 ± 0.157
2.215AsnSer: 2.215 ± 0.268
1.38AsnThr: 1.38 ± 0.182
2.038AsnVal: 2.038 ± 0.192
0.064AsnTrp: 0.064 ± 0.031
2.52AsnTyr: 2.52 ± 0.317
0.0AsnXaa: 0.0 ± 0.0
Pro
10.913ProAla: 10.913 ± 0.799
0.209ProCys: 0.209 ± 0.067
3.499ProAsp: 3.499 ± 0.277
3.226ProGlu: 3.226 ± 0.286
1.396ProPhe: 1.396 ± 0.189
2.985ProGly: 2.985 ± 0.452
2.552ProHis: 2.552 ± 0.179
4.879ProIle: 4.879 ± 0.513
3.226ProLys: 3.226 ± 0.24
4.622ProLeu: 4.622 ± 0.481
0.305ProMet: 0.305 ± 0.073
2.375ProAsn: 2.375 ± 0.257
5.168ProPro: 5.168 ± 0.537
5.184ProGln: 5.184 ± 0.713
2.841ProArg: 2.841 ± 0.624
5.296ProSer: 5.296 ± 0.537
3.739ProThr: 3.739 ± 0.418
16.482ProVal: 16.482 ± 1.656
0.144ProTrp: 0.144 ± 0.052
4.75ProTyr: 4.75 ± 0.719
0.0ProXaa: 0.0 ± 0.0
Gln
3.242GlnAla: 3.242 ± 0.316
0.289GlnCys: 0.289 ± 0.108
1.589GlnAsp: 1.589 ± 0.157
2.616GlnGlu: 2.616 ± 0.278
1.428GlnPhe: 1.428 ± 0.287
3.515GlnGly: 3.515 ± 0.361
2.536GlnHis: 2.536 ± 0.279
1.685GlnIle: 1.685 ± 0.209
1.525GlnLys: 1.525 ± 0.179
1.22GlnLeu: 1.22 ± 0.179
0.369GlnMet: 0.369 ± 0.079
2.343GlnAsn: 2.343 ± 0.323
4.494GlnPro: 4.494 ± 0.509
4.542GlnGln: 4.542 ± 0.515
1.942GlnArg: 1.942 ± 0.272
4.076GlnSer: 4.076 ± 0.348
1.894GlnThr: 1.894 ± 0.22
2.391GlnVal: 2.391 ± 0.262
0.321GlnTrp: 0.321 ± 0.134
3.836GlnTyr: 3.836 ± 0.417
0.0GlnXaa: 0.0 ± 0.0
Arg
2.584ArgAla: 2.584 ± 0.245
0.257ArgCys: 0.257 ± 0.075
2.76ArgAsp: 2.76 ± 0.424
1.332ArgGlu: 1.332 ± 0.236
0.738ArgPhe: 0.738 ± 0.117
1.605ArgGly: 1.605 ± 0.183
1.155ArgHis: 1.155 ± 0.133
1.493ArgIle: 1.493 ± 0.154
1.493ArgLys: 1.493 ± 0.169
1.621ArgLeu: 1.621 ± 0.186
0.353ArgMet: 0.353 ± 0.068
1.509ArgAsn: 1.509 ± 0.196
4.333ArgPro: 4.333 ± 0.931
1.797ArgGln: 1.797 ± 0.198
1.797ArgArg: 1.797 ± 0.307
2.295ArgSer: 2.295 ± 0.371
2.006ArgThr: 2.006 ± 0.172
2.311ArgVal: 2.311 ± 0.222
0.193ArgTrp: 0.193 ± 0.061
2.07ArgTyr: 2.07 ± 0.234
0.0ArgXaa: 0.0 ± 0.0
Ser
8.217SerAla: 8.217 ± 0.692
0.69SerCys: 0.69 ± 0.152
2.295SerAsp: 2.295 ± 0.203
2.167SerGlu: 2.167 ± 0.226
2.632SerPhe: 2.632 ± 0.199
7.158SerGly: 7.158 ± 0.813
3.434SerHis: 3.434 ± 0.513
3.306SerIle: 3.306 ± 0.25
2.006SerLys: 2.006 ± 0.195
4.766SerLeu: 4.766 ± 0.345
0.514SerMet: 0.514 ± 0.098
2.616SerAsn: 2.616 ± 0.374
3.691SerPro: 3.691 ± 0.339
5.232SerGln: 5.232 ± 0.414
2.921SerArg: 2.921 ± 0.235
9.18SerSer: 9.18 ± 0.783
2.889SerThr: 2.889 ± 0.392
4.766SerVal: 4.766 ± 0.294
0.193SerTrp: 0.193 ± 0.054
6.468SerTyr: 6.468 ± 0.466
0.0SerXaa: 0.0 ± 0.0
Thr
4.927ThrAla: 4.927 ± 0.381
0.353ThrCys: 0.353 ± 0.089
1.123ThrAsp: 1.123 ± 0.139
2.552ThrGlu: 2.552 ± 0.382
0.963ThrPhe: 0.963 ± 0.173
4.092ThrGly: 4.092 ± 0.297
0.963ThrHis: 0.963 ± 0.114
1.589ThrIle: 1.589 ± 0.186
2.167ThrLys: 2.167 ± 0.218
1.813ThrLeu: 1.813 ± 0.185
0.209ThrMet: 0.209 ± 0.083
1.3ThrAsn: 1.3 ± 0.213
3.771ThrPro: 3.771 ± 0.345
1.493ThrGln: 1.493 ± 0.209
1.573ThrArg: 1.573 ± 0.242
2.792ThrSer: 2.792 ± 0.314
4.478ThrThr: 4.478 ± 1.11
4.012ThrVal: 4.012 ± 0.283
0.096ThrTrp: 0.096 ± 0.034
3.563ThrTyr: 3.563 ± 0.39
0.0ThrXaa: 0.0 ± 0.0
Val
16.707ValAla: 16.707 ± 1.326
0.738ValCys: 0.738 ± 0.109
3.579ValAsp: 3.579 ± 0.259
5.697ValGlu: 5.697 ± 0.656
1.669ValPhe: 1.669 ± 0.201
2.552ValGly: 2.552 ± 0.369
4.975ValHis: 4.975 ± 0.559
2.375ValIle: 2.375 ± 0.2
5.248ValLys: 5.248 ± 0.478
4.333ValLeu: 4.333 ± 0.255
0.449ValMet: 0.449 ± 0.096
2.167ValAsn: 2.167 ± 0.193
8.714ValPro: 8.714 ± 1.229
2.937ValGln: 2.937 ± 0.241
3.579ValArg: 3.579 ± 0.249
5.649ValSer: 5.649 ± 0.406
3.033ValThr: 3.033 ± 0.274
10.111ValVal: 10.111 ± 0.72
0.16ValTrp: 0.16 ± 0.051
3.755ValTyr: 3.755 ± 0.275
0.0ValXaa: 0.0 ± 0.0
Trp
0.193TrpAla: 0.193 ± 0.052
0.016TrpCys: 0.016 ± 0.017
0.064TrpAsp: 0.064 ± 0.032
0.241TrpGlu: 0.241 ± 0.07
0.08TrpPhe: 0.08 ± 0.035
0.401TrpGly: 0.401 ± 0.13
0.112TrpHis: 0.112 ± 0.039
0.016TrpIle: 0.016 ± 0.016
0.241TrpLys: 0.241 ± 0.063
0.177TrpLeu: 0.177 ± 0.055
0.53TrpMet: 0.53 ± 0.086
0.305TrpAsn: 0.305 ± 0.153
0.289TrpPro: 0.289 ± 0.134
0.209TrpGln: 0.209 ± 0.063
0.128TrpArg: 0.128 ± 0.039
0.321TrpSer: 0.321 ± 0.071
0.193TrpThr: 0.193 ± 0.058
0.225TrpVal: 0.225 ± 0.055
0.225TrpTrp: 0.225 ± 0.057
0.096TrpTyr: 0.096 ± 0.035
0.0TrpXaa: 0.0 ± 0.0
Tyr
8.634TyrAla: 8.634 ± 0.822
0.241TyrCys: 0.241 ± 0.068
2.825TyrAsp: 2.825 ± 0.294
3.691TyrGlu: 3.691 ± 0.279
0.77TyrPhe: 0.77 ± 0.12
6.323TyrGly: 6.323 ± 0.625
3.434TyrHis: 3.434 ± 0.421
1.765TyrIle: 1.765 ± 0.185
2.68TyrLys: 2.68 ± 0.224
1.685TyrLeu: 1.685 ± 0.194
0.658TyrMet: 0.658 ± 0.094
2.552TyrAsn: 2.552 ± 0.287
3.932TyrPro: 3.932 ± 0.581
2.391TyrGln: 2.391 ± 0.272
1.797TyrArg: 1.797 ± 0.2
9.244TyrSer: 9.244 ± 0.719
3.787TyrThr: 3.787 ± 0.282
2.953TyrVal: 2.953 ± 0.259
0.273TyrTrp: 0.273 ± 0.076
2.728TyrTyr: 2.728 ± 0.226
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 283 proteins (62312 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski