Amino acid dipepetide frequency for Arcticibacterium luteifluviistationis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.186AlaAla: 5.186 ± 0.087	0.648AlaCys: 0.648 ± 0.022	3.652AlaAsp: 3.652 ± 0.057	4.369AlaGlu: 4.369 ± 0.062	3.592AlaPhe: 3.592 ± 0.049	4.871AlaGly: 4.871 ± 0.072	1.012AlaHis: 1.012 ± 0.026	5.099AlaIle: 5.099 ± 0.065	4.59AlaLys: 4.59 ± 0.072	6.3AlaLeu: 6.3 ± 0.081	1.612AlaMet: 1.612 ± 0.044	3.741AlaAsn: 3.741 ± 0.064	2.065AlaPro: 2.065 ± 0.045	2.214AlaGln: 2.214 ± 0.037	2.003AlaArg: 2.003 ± 0.039	4.861AlaSer: 4.861 ± 0.082	3.876AlaThr: 3.876 ± 0.12	4.379AlaVal: 4.379 ± 0.072	0.71AlaTrp: 0.71 ± 0.023	2.635AlaTyr: 2.635 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.448CysAla: 0.448 ± 0.019	0.098CysCys: 0.098 ± 0.008	0.44CysAsp: 0.44 ± 0.017	0.539CysGlu: 0.539 ± 0.022	0.428CysPhe: 0.428 ± 0.016	0.663CysGly: 0.663 ± 0.052	0.216CysHis: 0.216 ± 0.012	0.506CysIle: 0.506 ± 0.019	0.468CysLys: 0.468 ± 0.019	0.742CysLeu: 0.742 ± 0.024	0.144CysMet: 0.144 ± 0.01	0.415CysAsn: 0.415 ± 0.019	0.369CysPro: 0.369 ± 0.021	0.297CysGln: 0.297 ± 0.015	0.241CysArg: 0.241 ± 0.014	0.663CysSer: 0.663 ± 0.033	0.56CysThr: 0.56 ± 0.033	0.483CysVal: 0.483 ± 0.021	0.062CysTrp: 0.062 ± 0.007	0.299CysTyr: 0.299 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	3.802AspAla: 3.802 ± 0.057	0.405AspCys: 0.405 ± 0.018	2.788AspAsp: 2.788 ± 0.053	3.503AspGlu: 3.503 ± 0.058	3.675AspPhe: 3.675 ± 0.057	4.437AspGly: 4.437 ± 0.086	0.787AspHis: 0.787 ± 0.023	4.319AspIle: 4.319 ± 0.059	3.923AspLys: 3.923 ± 0.057	5.492AspLeu: 5.492 ± 0.068	1.215AspMet: 1.215 ± 0.029	3.043AspAsn: 3.043 ± 0.052	1.764AspPro: 1.764 ± 0.04	1.463AspGln: 1.463 ± 0.031	1.861AspArg: 1.861 ± 0.04	3.545AspSer: 3.545 ± 0.065	2.553AspThr: 2.553 ± 0.051	3.455AspVal: 3.455 ± 0.052	0.859AspTrp: 0.859 ± 0.025	2.561AspTyr: 2.561 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	4.499GluAla: 4.499 ± 0.07	0.342GluCys: 0.342 ± 0.015	3.428GluAsp: 3.428 ± 0.047	4.785GluGlu: 4.785 ± 0.081	2.785GluPhe: 2.785 ± 0.046	4.213GluGly: 4.213 ± 0.056	1.118GluHis: 1.118 ± 0.032	5.377GluIle: 5.377 ± 0.07	5.508GluLys: 5.508 ± 0.078	6.186GluLeu: 6.186 ± 0.081	1.726GluMet: 1.726 ± 0.037	4.606GluAsn: 4.606 ± 0.064	1.875GluPro: 1.875 ± 0.04	2.137GluGln: 2.137 ± 0.046	2.485GluArg: 2.485 ± 0.043	3.873GluSer: 3.873 ± 0.048	3.627GluThr: 3.627 ± 0.051	4.375GluVal: 4.375 ± 0.06	0.706GluTrp: 0.706 ± 0.022	2.248GluTyr: 2.248 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	2.964PheAla: 2.964 ± 0.047	0.445PheCys: 0.445 ± 0.018	3.3PheAsp: 3.3 ± 0.049	3.568PheGlu: 3.568 ± 0.06	2.631PhePhe: 2.631 ± 0.054	3.678PheGly: 3.678 ± 0.055	0.836PheHis: 0.836 ± 0.024	3.614PheIle: 3.614 ± 0.063	3.598PheLys: 3.598 ± 0.057	4.886PheLeu: 4.886 ± 0.079	1.114PheMet: 1.114 ± 0.031	2.968PheAsn: 2.968 ± 0.052	1.703PhePro: 1.703 ± 0.037	1.62PheGln: 1.62 ± 0.03	1.665PheArg: 1.665 ± 0.034	4.137PheSer: 4.137 ± 0.064	2.971PheThr: 2.971 ± 0.055	3.038PheVal: 3.038 ± 0.05	0.651PheTrp: 0.651 ± 0.022	2.074PheTyr: 2.074 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.383GlyAla: 4.383 ± 0.071	0.695GlyCys: 0.695 ± 0.033	3.898GlyAsp: 3.898 ± 0.066	4.185GlyGlu: 4.185 ± 0.056	3.926GlyPhe: 3.926 ± 0.053	5.401GlyGly: 5.401 ± 0.097	1.223GlyHis: 1.223 ± 0.029	5.6GlyIle: 5.6 ± 0.061	5.009GlyLys: 5.009 ± 0.075	6.767GlyLeu: 6.767 ± 0.075	1.684GlyMet: 1.684 ± 0.038	4.053GlyAsn: 4.053 ± 0.077	1.562GlyPro: 1.562 ± 0.033	2.289GlyGln: 2.289 ± 0.039	2.426GlyArg: 2.426 ± 0.046	4.877GlySer: 4.877 ± 0.092	4.565GlyThr: 4.565 ± 0.164	4.696GlyVal: 4.696 ± 0.068	0.839GlyTrp: 0.839 ± 0.025	2.918GlyTyr: 2.918 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.011HisAla: 1.011 ± 0.026	0.157HisCys: 0.157 ± 0.009	0.764HisAsp: 0.764 ± 0.022	1.011HisGlu: 1.011 ± 0.025	1.102HisPhe: 1.102 ± 0.027	1.202HisGly: 1.202 ± 0.033	0.447HisHis: 0.447 ± 0.017	1.165HisIle: 1.165 ± 0.029	1.015HisLys: 1.015 ± 0.028	1.667HisLeu: 1.667 ± 0.039	0.31HisMet: 0.31 ± 0.013	0.788HisAsn: 0.788 ± 0.022	0.856HisPro: 0.856 ± 0.023	0.605HisGln: 0.605 ± 0.022	0.59HisArg: 0.59 ± 0.021	1.015HisSer: 1.015 ± 0.027	0.904HisThr: 0.904 ± 0.028	0.889HisVal: 0.889 ± 0.025	0.232HisTrp: 0.232 ± 0.014	0.775HisTyr: 0.775 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	4.919IleAla: 4.919 ± 0.07	0.688IleCys: 0.688 ± 0.026	4.69IleAsp: 4.69 ± 0.06	4.944IleGlu: 4.944 ± 0.064	3.305IlePhe: 3.305 ± 0.063	5.288IleGly: 5.288 ± 0.075	1.162IleHis: 1.162 ± 0.03	5.083IleIle: 5.083 ± 0.063	5.239IleLys: 5.239 ± 0.064	6.76IleLeu: 6.76 ± 0.091	1.352IleMet: 1.352 ± 0.036	4.354IleAsn: 4.354 ± 0.058	3.157IlePro: 3.157 ± 0.05	2.345IleGln: 2.345 ± 0.04	2.493IleArg: 2.493 ± 0.045	5.878IleSer: 5.878 ± 0.069	4.181IleThr: 4.181 ± 0.081	3.988IleVal: 3.988 ± 0.049	0.748IleTrp: 0.748 ± 0.025	2.529IleTyr: 2.529 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.1LysAla: 5.1 ± 0.073	0.344LysCys: 0.344 ± 0.015	4.114LysAsp: 4.114 ± 0.058	5.717LysGlu: 5.717 ± 0.079	2.584LysPhe: 2.584 ± 0.041	4.815LysGly: 4.815 ± 0.07	1.201LysHis: 1.201 ± 0.032	5.152LysIle: 5.152 ± 0.067	5.813LysLys: 5.813 ± 0.095	6.277LysLeu: 6.277 ± 0.071	1.915LysMet: 1.915 ± 0.039	4.3LysAsn: 4.3 ± 0.055	2.673LysPro: 2.673 ± 0.049	1.968LysGln: 1.968 ± 0.039	2.726LysArg: 2.726 ± 0.051	4.728LysSer: 4.728 ± 0.062	4.341LysThr: 4.341 ± 0.066	4.778LysVal: 4.778 ± 0.071	0.921LysTrp: 0.921 ± 0.025	2.805LysTyr: 2.805 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	6.666LeuAla: 6.666 ± 0.082	0.717LeuCys: 0.717 ± 0.024	5.034LeuAsp: 5.034 ± 0.064	6.116LeuGlu: 6.116 ± 0.078	4.717LeuPhe: 4.717 ± 0.077	6.24LeuGly: 6.24 ± 0.074	1.404LeuHis: 1.404 ± 0.033	6.803LeuIle: 6.803 ± 0.091	7.567LeuLys: 7.567 ± 0.091	8.668LeuLeu: 8.668 ± 0.117	2.153LeuMet: 2.153 ± 0.04	5.665LeuAsn: 5.665 ± 0.063	3.739LeuPro: 3.739 ± 0.051	2.689LeuGln: 2.689 ± 0.044	3.323LeuArg: 3.323 ± 0.054	7.417LeuSer: 7.417 ± 0.071	5.305LeuThr: 5.305 ± 0.071	5.527LeuVal: 5.527 ± 0.064	0.908LeuTrp: 0.908 ± 0.026	3.064LeuTyr: 3.064 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	1.916MetAla: 1.916 ± 0.038	0.124MetCys: 0.124 ± 0.009	1.229MetAsp: 1.229 ± 0.03	1.507MetGlu: 1.507 ± 0.035	0.803MetPhe: 0.803 ± 0.027	1.579MetGly: 1.579 ± 0.037	0.37MetHis: 0.37 ± 0.016	1.368MetIle: 1.368 ± 0.034	2.078MetLys: 2.078 ± 0.038	1.968MetLeu: 1.968 ± 0.043	0.593MetMet: 0.593 ± 0.021	1.267MetAsn: 1.267 ± 0.033	1.02MetPro: 1.02 ± 0.024	0.706MetGln: 0.706 ± 0.022	0.8MetArg: 0.8 ± 0.025	1.413MetSer: 1.413 ± 0.031	1.192MetThr: 1.192 ± 0.031	1.446MetVal: 1.446 ± 0.03	0.181MetTrp: 0.181 ± 0.01	0.614MetTyr: 0.614 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.811AsnAla: 3.811 ± 0.06	0.522AsnCys: 0.522 ± 0.033	3.057AsnAsp: 3.057 ± 0.059	3.448AsnGlu: 3.448 ± 0.045	2.909AsnPhe: 2.909 ± 0.046	4.533AsnGly: 4.533 ± 0.089	0.993AsnHis: 0.993 ± 0.026	4.342AsnIle: 4.342 ± 0.066	3.757AsnLys: 3.757 ± 0.054	5.52AsnLeu: 5.52 ± 0.069	1.141AsnMet: 1.141 ± 0.027	3.568AsnAsn: 3.568 ± 0.094	2.819AsnPro: 2.819 ± 0.044	2.144AsnGln: 2.144 ± 0.042	2.001AsnArg: 2.001 ± 0.042	4.275AsnSer: 4.275 ± 0.084	3.605AsnThr: 3.605 ± 0.09	3.417AsnVal: 3.417 ± 0.054	0.792AsnTrp: 0.792 ± 0.021	2.683AsnTyr: 2.683 ± 0.044	0.0AsnXaa: 0.0 ± 0.0
Pro	2.354ProAla: 2.354 ± 0.043	0.209ProCys: 0.209 ± 0.01	2.207ProAsp: 2.207 ± 0.041	3.159ProGlu: 3.159 ± 0.056	2.004ProPhe: 2.004 ± 0.041	2.141ProGly: 2.141 ± 0.043	0.611ProHis: 0.611 ± 0.02	2.615ProIle: 2.615 ± 0.046	2.384ProLys: 2.384 ± 0.043	3.052ProLeu: 3.052 ± 0.051	0.746ProMet: 0.746 ± 0.024	2.35ProAsn: 2.35 ± 0.051	0.935ProPro: 0.935 ± 0.028	1.063ProGln: 1.063 ± 0.026	0.967ProArg: 0.967 ± 0.026	2.725ProSer: 2.725 ± 0.053	2.226ProThr: 2.226 ± 0.062	2.34ProVal: 2.34 ± 0.04	0.412ProTrp: 0.412 ± 0.018	1.438ProTyr: 1.438 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.045GlnAla: 2.045 ± 0.036	0.167GlnCys: 0.167 ± 0.01	1.57GlnAsp: 1.57 ± 0.033	2.124GlnGlu: 2.124 ± 0.044	1.523GlnPhe: 1.523 ± 0.036	1.874GlnGly: 1.874 ± 0.044	0.492GlnHis: 0.492 ± 0.02	2.505GlnIle: 2.505 ± 0.037	2.626GlnLys: 2.626 ± 0.04	2.873GlnLeu: 2.873 ± 0.045	0.776GlnMet: 0.776 ± 0.023	2.197GlnAsn: 2.197 ± 0.033	1.017GlnPro: 1.017 ± 0.025	1.017GlnGln: 1.017 ± 0.028	1.117GlnArg: 1.117 ± 0.029	2.092GlnSer: 2.092 ± 0.041	1.884GlnThr: 1.884 ± 0.033	1.986GlnVal: 1.986 ± 0.037	0.399GlnTrp: 0.399 ± 0.016	1.21GlnTyr: 1.21 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	2.181ArgAla: 2.181 ± 0.04	0.205ArgCys: 0.205 ± 0.014	1.804ArgAsp: 1.804 ± 0.039	2.188ArgGlu: 2.188 ± 0.045	1.857ArgPhe: 1.857 ± 0.034	2.078ArgGly: 2.078 ± 0.042	0.564ArgHis: 0.564 ± 0.017	2.68ArgIle: 2.68 ± 0.038	2.671ArgLys: 2.671 ± 0.048	3.216ArgLeu: 3.216 ± 0.047	0.885ArgMet: 0.885 ± 0.022	2.056ArgAsn: 2.056 ± 0.041	1.177ArgPro: 1.177 ± 0.029	1.098ArgGln: 1.098 ± 0.031	1.39ArgArg: 1.39 ± 0.038	1.991ArgSer: 1.991 ± 0.037	1.87ArgThr: 1.87 ± 0.036	2.182ArgVal: 2.182 ± 0.04	0.42ArgTrp: 0.42 ± 0.018	1.401ArgTyr: 1.401 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	4.246SerAla: 4.246 ± 0.077	0.789SerCys: 0.789 ± 0.031	3.874SerAsp: 3.874 ± 0.06	4.436SerGlu: 4.436 ± 0.059	4.211SerPhe: 4.211 ± 0.053	5.497SerGly: 5.497 ± 0.109	1.168SerHis: 1.168 ± 0.027	5.336SerIle: 5.336 ± 0.072	4.869SerLys: 4.869 ± 0.067	6.841SerLeu: 6.841 ± 0.071	1.441SerMet: 1.441 ± 0.035	4.102SerAsn: 4.102 ± 0.086	2.705SerPro: 2.705 ± 0.054	2.444SerGln: 2.444 ± 0.053	2.267SerArg: 2.267 ± 0.038	5.623SerSer: 5.623 ± 0.126	4.05SerThr: 4.05 ± 0.102	4.3SerVal: 4.3 ± 0.075	0.842SerTrp: 0.842 ± 0.027	2.885SerTyr: 2.885 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	4.284ThrAla: 4.284 ± 0.144	0.482ThrCys: 0.482 ± 0.034	3.308ThrAsp: 3.308 ± 0.057	3.615ThrGlu: 3.615 ± 0.06	3.087ThrPhe: 3.087 ± 0.054	4.586ThrGly: 4.586 ± 0.116	0.906ThrHis: 0.906 ± 0.027	4.12ThrIle: 4.12 ± 0.089	3.447ThrLys: 3.447 ± 0.043	5.537ThrLeu: 5.537 ± 0.064	0.979ThrMet: 0.979 ± 0.027	3.097ThrAsn: 3.097 ± 0.067	2.435ThrPro: 2.435 ± 0.062	1.671ThrGln: 1.671 ± 0.039	1.553ThrArg: 1.553 ± 0.032	4.121ThrSer: 4.121 ± 0.094	3.317ThrThr: 3.317 ± 0.101	3.813ThrVal: 3.813 ± 0.115	0.735ThrTrp: 0.735 ± 0.032	2.47ThrTyr: 2.47 ± 0.071	0.0ThrXaa: 0.0 ± 0.0
Val	4.23ValAla: 4.23 ± 0.066	0.625ValCys: 0.625 ± 0.029	3.344ValAsp: 3.344 ± 0.05	3.67ValGlu: 3.67 ± 0.053	3.412ValPhe: 3.412 ± 0.053	4.225ValGly: 4.225 ± 0.073	0.936ValHis: 0.936 ± 0.027	4.373ValIle: 4.373 ± 0.053	4.397ValLys: 4.397 ± 0.058	6.062ValLeu: 6.062 ± 0.076	1.342ValMet: 1.342 ± 0.03	3.833ValAsn: 3.833 ± 0.063	2.244ValPro: 2.244 ± 0.036	1.641ValGln: 1.641 ± 0.03	2.055ValArg: 2.055 ± 0.039	4.918ValSer: 4.918 ± 0.079	3.599ValThr: 3.599 ± 0.122	3.977ValVal: 3.977 ± 0.076	0.69ValTrp: 0.69 ± 0.021	2.307ValTyr: 2.307 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	0.782TrpAla: 0.782 ± 0.025	0.088TrpCys: 0.088 ± 0.008	0.672TrpAsp: 0.672 ± 0.023	0.738TrpGlu: 0.738 ± 0.022	0.593TrpPhe: 0.593 ± 0.02	0.85TrpGly: 0.85 ± 0.025	0.273TrpHis: 0.273 ± 0.013	0.754TrpIle: 0.754 ± 0.023	0.785TrpLys: 0.785 ± 0.023	1.083TrpLeu: 1.083 ± 0.031	0.31TrpMet: 0.31 ± 0.014	0.694TrpAsn: 0.694 ± 0.024	0.319TrpPro: 0.319 ± 0.014	0.51TrpGln: 0.51 ± 0.018	0.463TrpArg: 0.463 ± 0.018	0.836TrpSer: 0.836 ± 0.041	0.641TrpThr: 0.641 ± 0.024	0.723TrpVal: 0.723 ± 0.022	0.181TrpTrp: 0.181 ± 0.011	0.482TrpTyr: 0.482 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.59TyrAla: 2.59 ± 0.039	0.332TyrCys: 0.332 ± 0.015	2.278TyrAsp: 2.278 ± 0.042	2.277TyrGlu: 2.277 ± 0.04	2.318TyrPhe: 2.318 ± 0.043	2.824TyrGly: 2.824 ± 0.043	0.788TyrHis: 0.788 ± 0.023	2.293TyrIle: 2.293 ± 0.042	2.528TyrLys: 2.528 ± 0.043	3.825TyrLeu: 3.825 ± 0.058	0.735TyrMet: 0.735 ± 0.024	2.239TyrAsn: 2.239 ± 0.046	1.502TyrPro: 1.502 ± 0.035	1.574TyrGln: 1.574 ± 0.036	1.487TyrArg: 1.487 ± 0.039	2.937TyrSer: 2.937 ± 0.053	2.293TyrThr: 2.293 ± 0.064	2.086TyrVal: 2.086 ± 0.04	0.49TyrTrp: 0.49 ± 0.019	1.694TyrTyr: 1.694 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4329 proteins (1600995 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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