Amino acid dipepetide frequency for Human adenovirus F serotype 41 (HAdV-41) (Human adenovirus 41)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.597AlaAla: 7.597 ± 1.17
0.795AlaCys: 0.795 ± 0.384
3.534AlaAsp: 3.534 ± 0.431
3.71AlaGlu: 3.71 ± 0.667
2.65AlaPhe: 2.65 ± 0.443
4.064AlaGly: 4.064 ± 0.66
1.59AlaHis: 1.59 ± 0.346
2.915AlaIle: 2.915 ± 0.631
1.678AlaLys: 1.678 ± 0.439
9.452AlaLeu: 9.452 ± 1.086
1.943AlaMet: 1.943 ± 0.443
3.887AlaAsn: 3.887 ± 0.659
5.124AlaPro: 5.124 ± 0.707
2.739AlaGln: 2.739 ± 0.482
5.3AlaArg: 5.3 ± 0.985
5.83AlaSer: 5.83 ± 0.761
4.24AlaThr: 4.24 ± 0.598
5.654AlaVal: 5.654 ± 0.635
0.883AlaTrp: 0.883 ± 0.282
2.473AlaTyr: 2.473 ± 0.438
0.0AlaXaa: 0.0 ± 0.0
Cys
1.767CysAla: 1.767 ± 0.468
0.883CysCys: 0.883 ± 0.297
0.795CysAsp: 0.795 ± 0.246
1.06CysGlu: 1.06 ± 0.216
0.442CysPhe: 0.442 ± 0.196
1.413CysGly: 1.413 ± 0.393
0.53CysHis: 0.53 ± 0.2
0.707CysIle: 0.707 ± 0.255
0.53CysLys: 0.53 ± 0.266
1.767CysLeu: 1.767 ± 0.47
0.265CysMet: 0.265 ± 0.16
0.707CysAsn: 0.707 ± 0.212
0.53CysPro: 0.53 ± 0.209
0.618CysGln: 0.618 ± 0.194
1.148CysArg: 1.148 ± 0.413
1.06CysSer: 1.06 ± 0.29
1.148CysThr: 1.148 ± 0.325
1.06CysVal: 1.06 ± 0.382
0.442CysTrp: 0.442 ± 0.225
1.237CysTyr: 1.237 ± 0.275
0.0CysXaa: 0.0 ± 0.0
Asp
3.18AspAla: 3.18 ± 0.522
0.618AspCys: 0.618 ± 0.242
2.562AspAsp: 2.562 ± 0.502
3.799AspGlu: 3.799 ± 0.656
2.297AspPhe: 2.297 ± 0.464
2.562AspGly: 2.562 ± 0.481
0.618AspHis: 0.618 ± 0.214
1.855AspIle: 1.855 ± 0.452
1.413AspLys: 1.413 ± 0.367
4.417AspLeu: 4.417 ± 0.591
0.972AspMet: 0.972 ± 0.302
2.208AspAsn: 2.208 ± 0.613
3.004AspPro: 3.004 ± 0.433
1.59AspGln: 1.59 ± 0.311
3.092AspArg: 3.092 ± 0.759
3.092AspSer: 3.092 ± 0.459
2.739AspThr: 2.739 ± 0.645
2.827AspVal: 2.827 ± 0.503
0.53AspTrp: 0.53 ± 0.158
2.032AspTyr: 2.032 ± 0.488
0.0AspXaa: 0.0 ± 0.0
Glu
3.887GluAla: 3.887 ± 0.67
1.06GluCys: 1.06 ± 0.313
4.24GluAsp: 4.24 ± 0.611
7.951GluGlu: 7.951 ± 1.92
1.59GluPhe: 1.59 ± 0.25
3.622GluGly: 3.622 ± 0.619
1.06GluHis: 1.06 ± 0.286
3.092GluIle: 3.092 ± 0.602
2.739GluLys: 2.739 ± 0.477
6.802GluLeu: 6.802 ± 0.975
1.06GluMet: 1.06 ± 0.277
3.799GluAsn: 3.799 ± 0.583
3.18GluPro: 3.18 ± 0.441
2.562GluGln: 2.562 ± 0.619
4.329GluArg: 4.329 ± 0.737
2.739GluSer: 2.739 ± 0.48
3.18GluThr: 3.18 ± 0.505
3.975GluVal: 3.975 ± 0.515
0.795GluTrp: 0.795 ± 0.26
0.795GluTyr: 0.795 ± 0.252
0.0GluXaa: 0.0 ± 0.0
Phe
3.18PheAla: 3.18 ± 0.499
0.618PheCys: 0.618 ± 0.275
2.12PheAsp: 2.12 ± 0.508
1.855PheGlu: 1.855 ± 0.487
1.943PhePhe: 1.943 ± 0.419
0.883PheGly: 0.883 ± 0.32
1.325PheHis: 1.325 ± 0.302
1.767PheIle: 1.767 ± 0.415
1.59PheLys: 1.59 ± 0.448
3.534PheLeu: 3.534 ± 0.521
1.413PheMet: 1.413 ± 0.283
2.473PheAsn: 2.473 ± 0.604
1.678PhePro: 1.678 ± 0.333
2.297PheGln: 2.297 ± 0.357
2.297PheArg: 2.297 ± 0.392
2.915PheSer: 2.915 ± 0.459
2.385PheThr: 2.385 ± 0.427
2.739PheVal: 2.739 ± 0.41
0.353PheTrp: 0.353 ± 0.19
1.943PheTyr: 1.943 ± 0.377
0.0PheXaa: 0.0 ± 0.0
Gly
4.859GlyAla: 4.859 ± 0.811
1.06GlyCys: 1.06 ± 0.321
2.12GlyAsp: 2.12 ± 0.394
2.562GlyGlu: 2.562 ± 0.525
2.12GlyPhe: 2.12 ± 0.358
3.975GlyGly: 3.975 ± 0.604
1.502GlyHis: 1.502 ± 0.387
2.032GlyIle: 2.032 ± 0.402
2.208GlyLys: 2.208 ± 0.473
6.802GlyLeu: 6.802 ± 0.957
1.325GlyMet: 1.325 ± 0.288
3.269GlyAsn: 3.269 ± 0.619
2.739GlyPro: 2.739 ± 0.489
3.004GlyGln: 3.004 ± 0.665
4.329GlyArg: 4.329 ± 0.614
4.859GlySer: 4.859 ± 0.619
3.534GlyThr: 3.534 ± 0.512
4.682GlyVal: 4.682 ± 0.722
0.972GlyTrp: 0.972 ± 0.306
1.325GlyTyr: 1.325 ± 0.317
0.0GlyXaa: 0.0 ± 0.0
His
1.413HisAla: 1.413 ± 0.261
0.972HisCys: 0.972 ± 0.424
0.707HisAsp: 0.707 ± 0.224
0.795HisGlu: 0.795 ± 0.264
0.53HisPhe: 0.53 ± 0.192
1.237HisGly: 1.237 ± 0.423
0.707HisHis: 0.707 ± 0.198
1.237HisIle: 1.237 ± 0.338
0.53HisLys: 0.53 ± 0.253
1.855HisLeu: 1.855 ± 0.429
0.088HisMet: 0.088 ± 0.094
1.06HisAsn: 1.06 ± 0.332
1.767HisPro: 1.767 ± 0.53
0.972HisGln: 0.972 ± 0.266
1.678HisArg: 1.678 ± 0.289
1.06HisSer: 1.06 ± 0.3
0.795HisThr: 0.795 ± 0.326
1.237HisVal: 1.237 ± 0.296
0.353HisTrp: 0.353 ± 0.222
0.707HisTyr: 0.707 ± 0.223
0.0HisXaa: 0.0 ± 0.0
Ile
3.269IleAla: 3.269 ± 0.66
1.06IleCys: 1.06 ± 0.327
1.502IleAsp: 1.502 ± 0.423
1.678IleGlu: 1.678 ± 0.381
2.032IlePhe: 2.032 ± 0.478
2.65IleGly: 2.65 ± 0.493
0.53IleHis: 0.53 ± 0.194
1.678IleIle: 1.678 ± 0.456
2.385IleLys: 2.385 ± 0.392
4.24IleLeu: 4.24 ± 0.716
0.618IleMet: 0.618 ± 0.216
1.943IleAsn: 1.943 ± 0.448
2.385IlePro: 2.385 ± 0.489
1.678IleGln: 1.678 ± 0.4
1.767IleArg: 1.767 ± 0.452
3.18IleSer: 3.18 ± 0.541
3.534IleThr: 3.534 ± 0.781
2.473IleVal: 2.473 ± 0.581
0.177IleTrp: 0.177 ± 0.13
1.678IleTyr: 1.678 ± 0.369
0.0IleXaa: 0.0 ± 0.0
Lys
2.473LysAla: 2.473 ± 0.336
0.795LysCys: 0.795 ± 0.221
2.032LysAsp: 2.032 ± 0.425
2.65LysGlu: 2.65 ± 0.458
1.678LysPhe: 1.678 ± 0.301
2.562LysGly: 2.562 ± 0.44
0.883LysHis: 0.883 ± 0.239
2.208LysIle: 2.208 ± 0.445
2.208LysLys: 2.208 ± 0.547
3.092LysLeu: 3.092 ± 0.583
0.707LysMet: 0.707 ± 0.362
1.943LysAsn: 1.943 ± 0.313
1.855LysPro: 1.855 ± 0.454
1.59LysGln: 1.59 ± 0.511
3.269LysArg: 3.269 ± 0.861
1.767LysSer: 1.767 ± 0.424
2.562LysThr: 2.562 ± 0.635
3.18LysVal: 3.18 ± 0.557
0.353LysTrp: 0.353 ± 0.179
1.06LysTyr: 1.06 ± 0.254
0.0LysXaa: 0.0 ± 0.0
Leu
7.244LeuAla: 7.244 ± 0.95
1.678LeuCys: 1.678 ± 0.479
4.505LeuAsp: 4.505 ± 0.71
6.007LeuGlu: 6.007 ± 0.709
2.739LeuPhe: 2.739 ± 0.476
5.477LeuGly: 5.477 ± 0.689
2.473LeuHis: 2.473 ± 0.534
4.24LeuIle: 4.24 ± 0.62
5.389LeuLys: 5.389 ± 0.728
9.717LeuLeu: 9.717 ± 1.156
2.827LeuMet: 2.827 ± 0.477
5.124LeuAsn: 5.124 ± 0.627
6.537LeuPro: 6.537 ± 0.797
6.272LeuGln: 6.272 ± 0.619
7.332LeuArg: 7.332 ± 0.726
5.654LeuSer: 5.654 ± 0.705
6.89LeuThr: 6.89 ± 0.688
5.124LeuVal: 5.124 ± 0.636
1.148LeuTrp: 1.148 ± 0.33
4.24LeuTyr: 4.24 ± 0.764
0.0LeuXaa: 0.0 ± 0.0
Met
2.032MetAla: 2.032 ± 0.366
0.177MetCys: 0.177 ± 0.144
1.06MetAsp: 1.06 ± 0.224
2.385MetGlu: 2.385 ± 0.465
0.972MetPhe: 0.972 ± 0.399
1.413MetGly: 1.413 ± 0.274
1.148MetHis: 1.148 ± 0.395
0.795MetIle: 0.795 ± 0.306
0.883MetLys: 0.883 ± 0.309
2.385MetLeu: 2.385 ± 0.517
0.883MetMet: 0.883 ± 0.287
0.883MetAsn: 0.883 ± 0.32
1.502MetPro: 1.502 ± 0.343
1.148MetGln: 1.148 ± 0.303
1.325MetArg: 1.325 ± 0.342
1.59MetSer: 1.59 ± 0.358
1.06MetThr: 1.06 ± 0.297
0.883MetVal: 0.883 ± 0.285
0.442MetTrp: 0.442 ± 0.198
0.972MetTyr: 0.972 ± 0.226
0.0MetXaa: 0.0 ± 0.0
Asn
3.445AsnAla: 3.445 ± 0.744
1.148AsnCys: 1.148 ± 0.388
2.297AsnAsp: 2.297 ± 0.549
2.12AsnGlu: 2.12 ± 0.415
2.297AsnPhe: 2.297 ± 0.501
3.357AsnGly: 3.357 ± 0.745
0.795AsnHis: 0.795 ± 0.246
2.385AsnIle: 2.385 ± 0.537
2.297AsnLys: 2.297 ± 0.414
4.77AsnLeu: 4.77 ± 0.759
2.12AsnMet: 2.12 ± 0.574
2.915AsnAsn: 2.915 ± 0.679
3.799AsnPro: 3.799 ± 0.495
2.032AsnGln: 2.032 ± 0.45
2.473AsnArg: 2.473 ± 0.438
3.887AsnSer: 3.887 ± 0.725
1.943AsnThr: 1.943 ± 0.409
3.18AsnVal: 3.18 ± 0.512
0.883AsnTrp: 0.883 ± 0.345
2.208AsnTyr: 2.208 ± 0.504
0.0AsnXaa: 0.0 ± 0.0
Pro
4.505ProAla: 4.505 ± 0.661
0.795ProCys: 0.795 ± 0.287
2.473ProAsp: 2.473 ± 0.552
4.505ProGlu: 4.505 ± 0.757
3.092ProPhe: 3.092 ± 0.623
4.152ProGly: 4.152 ± 0.576
0.707ProHis: 0.707 ± 0.232
2.208ProIle: 2.208 ± 0.351
2.562ProLys: 2.562 ± 0.566
5.654ProLeu: 5.654 ± 1.013
1.325ProMet: 1.325 ± 0.346
3.004ProAsn: 3.004 ± 0.54
7.244ProPro: 7.244 ± 1.29
2.562ProGln: 2.562 ± 0.501
4.064ProArg: 4.064 ± 0.789
5.742ProSer: 5.742 ± 0.738
4.594ProThr: 4.594 ± 0.704
4.152ProVal: 4.152 ± 0.649
0.618ProTrp: 0.618 ± 0.263
2.12ProTyr: 2.12 ± 0.434
0.0ProXaa: 0.0 ± 0.0
Gln
4.152GlnAla: 4.152 ± 0.585
0.618GlnCys: 0.618 ± 0.244
1.767GlnAsp: 1.767 ± 0.391
3.18GlnGlu: 3.18 ± 0.491
1.237GlnPhe: 1.237 ± 0.281
2.208GlnGly: 2.208 ± 0.343
0.883GlnHis: 0.883 ± 0.226
2.208GlnIle: 2.208 ± 0.432
2.297GlnLys: 2.297 ± 0.455
4.24GlnLeu: 4.24 ± 0.685
1.59GlnMet: 1.59 ± 0.414
2.385GlnAsn: 2.385 ± 0.498
3.445GlnPro: 3.445 ± 0.529
2.65GlnGln: 2.65 ± 0.62
3.534GlnArg: 3.534 ± 0.604
4.064GlnSer: 4.064 ± 0.504
3.004GlnThr: 3.004 ± 0.481
2.739GlnVal: 2.739 ± 0.588
0.972GlnTrp: 0.972 ± 0.275
0.442GlnTyr: 0.442 ± 0.189
0.0GlnXaa: 0.0 ± 0.0
Arg
5.124ArgAla: 5.124 ± 1.063
1.59ArgCys: 1.59 ± 0.46
2.473ArgAsp: 2.473 ± 0.629
4.24ArgGlu: 4.24 ± 0.692
3.18ArgPhe: 3.18 ± 0.484
5.83ArgGly: 5.83 ± 0.802
0.883ArgHis: 0.883 ± 0.288
2.208ArgIle: 2.208 ± 0.364
2.473ArgLys: 2.473 ± 0.401
5.919ArgLeu: 5.919 ± 0.832
0.883ArgMet: 0.883 ± 0.242
3.269ArgAsn: 3.269 ± 0.51
4.594ArgPro: 4.594 ± 0.846
3.534ArgGln: 3.534 ± 0.527
8.039ArgArg: 8.039 ± 1.934
5.035ArgSer: 5.035 ± 0.714
3.799ArgThr: 3.799 ± 0.76
3.71ArgVal: 3.71 ± 0.508
1.502ArgTrp: 1.502 ± 0.333
2.473ArgTyr: 2.473 ± 0.448
0.0ArgXaa: 0.0 ± 0.0
Ser
6.095SerAla: 6.095 ± 0.562
1.325SerCys: 1.325 ± 0.387
2.385SerAsp: 2.385 ± 0.466
3.799SerGlu: 3.799 ± 0.531
2.827SerPhe: 2.827 ± 0.472
5.477SerGly: 5.477 ± 0.761
1.06SerHis: 1.06 ± 0.335
3.269SerIle: 3.269 ± 0.536
1.943SerLys: 1.943 ± 0.427
7.597SerLeu: 7.597 ± 0.93
1.413SerMet: 1.413 ± 0.39
3.622SerAsn: 3.622 ± 0.743
4.24SerPro: 4.24 ± 0.606
3.799SerGln: 3.799 ± 0.603
4.682SerArg: 4.682 ± 0.677
5.654SerSer: 5.654 ± 0.886
3.799SerThr: 3.799 ± 0.602
3.975SerVal: 3.975 ± 0.594
1.148SerTrp: 1.148 ± 0.375
2.739SerTyr: 2.739 ± 0.532
0.0SerXaa: 0.0 ± 0.0
Thr
4.064ThrAla: 4.064 ± 0.508
0.883ThrCys: 0.883 ± 0.29
2.65ThrAsp: 2.65 ± 0.566
2.473ThrGlu: 2.473 ± 0.364
2.915ThrPhe: 2.915 ± 0.468
3.092ThrGly: 3.092 ± 0.582
1.325ThrHis: 1.325 ± 0.343
2.473ThrIle: 2.473 ± 0.57
1.59ThrLys: 1.59 ± 0.364
7.862ThrLeu: 7.862 ± 0.835
1.502ThrMet: 1.502 ± 0.405
2.65ThrAsn: 2.65 ± 0.597
4.77ThrPro: 4.77 ± 0.67
2.562ThrGln: 2.562 ± 0.411
3.534ThrArg: 3.534 ± 0.683
3.534ThrSer: 3.534 ± 0.478
4.24ThrThr: 4.24 ± 0.83
4.152ThrVal: 4.152 ± 0.495
0.972ThrTrp: 0.972 ± 0.297
2.473ThrTyr: 2.473 ± 0.809
0.0ThrXaa: 0.0 ± 0.0
Val
4.682ValAla: 4.682 ± 0.824
1.06ValCys: 1.06 ± 0.393
3.357ValAsp: 3.357 ± 0.576
4.417ValGlu: 4.417 ± 0.882
2.65ValPhe: 2.65 ± 0.572
2.915ValGly: 2.915 ± 0.365
0.618ValHis: 0.618 ± 0.232
2.385ValIle: 2.385 ± 0.486
2.12ValLys: 2.12 ± 0.595
5.83ValLeu: 5.83 ± 0.572
1.237ValMet: 1.237 ± 0.379
2.65ValAsn: 2.65 ± 0.526
4.859ValPro: 4.859 ± 0.655
3.18ValGln: 3.18 ± 0.516
5.035ValArg: 5.035 ± 0.67
4.77ValSer: 4.77 ± 0.636
3.71ValThr: 3.71 ± 0.614
4.064ValVal: 4.064 ± 0.763
0.618ValTrp: 0.618 ± 0.185
2.473ValTyr: 2.473 ± 0.403
0.0ValXaa: 0.0 ± 0.0
Trp
0.53TrpAla: 0.53 ± 0.19
0.0TrpCys: 0.0 ± 0.0
1.325TrpAsp: 1.325 ± 0.457
1.06TrpGlu: 1.06 ± 0.281
0.53TrpPhe: 0.53 ± 0.245
1.06TrpGly: 1.06 ± 0.291
0.088TrpHis: 0.088 ± 0.087
0.265TrpIle: 0.265 ± 0.139
0.618TrpLys: 0.618 ± 0.199
1.148TrpLeu: 1.148 ± 0.328
0.442TrpMet: 0.442 ± 0.162
0.707TrpAsn: 0.707 ± 0.312
0.618TrpPro: 0.618 ± 0.223
0.972TrpGln: 0.972 ± 0.341
1.237TrpArg: 1.237 ± 0.34
1.678TrpSer: 1.678 ± 0.354
0.883TrpThr: 0.883 ± 0.271
0.177TrpVal: 0.177 ± 0.128
0.353TrpTrp: 0.353 ± 0.188
0.088TrpTyr: 0.088 ± 0.086
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.562TyrAla: 2.562 ± 0.571
0.972TyrCys: 0.972 ± 0.366
1.59TyrAsp: 1.59 ± 0.439
2.208TyrGlu: 2.208 ± 0.425
1.59TyrPhe: 1.59 ± 0.398
1.325TyrGly: 1.325 ± 0.321
0.972TyrHis: 0.972 ± 0.331
0.53TyrIle: 0.53 ± 0.195
1.413TyrLys: 1.413 ± 0.436
3.534TyrLeu: 3.534 ± 0.605
1.237TyrMet: 1.237 ± 0.279
1.855TyrAsn: 1.855 ± 0.569
2.208TyrPro: 2.208 ± 0.501
1.855TyrGln: 1.855 ± 0.361
2.297TyrArg: 2.297 ± 0.417
2.739TyrSer: 2.739 ± 0.484
1.678TyrThr: 1.678 ± 0.343
2.65TyrVal: 2.65 ± 0.453
0.265TyrTrp: 0.265 ± 0.142
0.53TyrTyr: 0.53 ± 0.232
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 34 proteins (11321 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski