Amino acid dipepetide frequency for Beihai partiti-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.985AlaAla: 2.985 ± 0.837
0.995AlaCys: 0.995 ± 0.755
4.975AlaAsp: 4.975 ± 3.775
0.995AlaGlu: 0.995 ± 0.755
1.99AlaPhe: 1.99 ± 1.345
3.98AlaGly: 3.98 ± 3.02
0.0AlaHis: 0.0 ± 0.0
7.96AlaIle: 7.96 ± 1.098
3.98AlaLys: 3.98 ± 1.593
5.97AlaLeu: 5.97 ± 0.247
0.0AlaMet: 0.0 ± 0.0
2.985AlaAsn: 2.985 ± 2.265
4.975AlaPro: 4.975 ± 2.348
2.985AlaGln: 2.985 ± 0.837
6.965AlaArg: 6.965 ± 0.425
6.965AlaSer: 6.965 ± 0.425
0.0AlaThr: 0.0 ± 0.0
3.98AlaVal: 3.98 ± 2.691
0.995AlaTrp: 0.995 ± 0.673
2.985AlaTyr: 2.985 ± 0.59
0.0AlaXaa: 0.0 ± 0.0
Cys
2.985CysAla: 2.985 ± 0.59
0.0CysCys: 0.0 ± 0.0
1.99CysAsp: 1.99 ± 0.082
0.0CysGlu: 0.0 ± 0.0
1.99CysPhe: 1.99 ± 0.082
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.995CysMet: 0.995 ± 0.673
0.0CysAsn: 0.0 ± 0.0
1.99CysPro: 1.99 ± 1.51
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.99CysTyr: 1.99 ± 0.082
0.0CysXaa: 0.0 ± 0.0
Asp
1.99AspAla: 1.99 ± 1.345
0.995AspCys: 0.995 ± 0.673
2.985AspAsp: 2.985 ± 0.837
1.99AspGlu: 1.99 ± 1.51
4.975AspPhe: 4.975 ± 0.92
5.97AspGly: 5.97 ± 1.675
0.0AspHis: 0.0 ± 0.0
5.97AspIle: 5.97 ± 0.247
1.99AspLys: 1.99 ± 1.345
3.98AspLeu: 3.98 ± 1.593
0.995AspMet: 0.995 ± 1.068
0.995AspAsn: 0.995 ± 0.673
5.97AspPro: 5.97 ± 1.181
2.985AspGln: 2.985 ± 0.59
1.99AspArg: 1.99 ± 0.082
4.975AspSer: 4.975 ± 0.92
5.97AspThr: 5.97 ± 1.675
4.975AspVal: 4.975 ± 0.508
1.99AspTrp: 1.99 ± 0.082
1.99AspTyr: 1.99 ± 1.345
0.0AspXaa: 0.0 ± 0.0
Glu
2.985GluAla: 2.985 ± 2.018
0.0GluCys: 0.0 ± 0.0
3.98GluAsp: 3.98 ± 0.165
3.98GluGlu: 3.98 ± 2.691
0.0GluPhe: 0.0 ± 0.0
1.99GluGly: 1.99 ± 0.082
0.0GluHis: 0.0 ± 0.0
1.99GluIle: 1.99 ± 1.345
2.985GluLys: 2.985 ± 0.837
3.98GluLeu: 3.98 ± 1.263
1.99GluMet: 1.99 ± 0.455
3.98GluAsn: 3.98 ± 0.165
0.995GluPro: 0.995 ± 0.673
0.0GluGln: 0.0 ± 0.0
5.97GluArg: 5.97 ± 1.181
3.98GluSer: 3.98 ± 1.593
1.99GluThr: 1.99 ± 1.51
2.985GluVal: 2.985 ± 0.59
1.99GluTrp: 1.99 ± 0.082
0.995GluTyr: 0.995 ± 0.673
0.0GluXaa: 0.0 ± 0.0
Phe
2.985PheAla: 2.985 ± 0.837
0.995PheCys: 0.995 ± 0.755
4.975PheAsp: 4.975 ± 0.508
1.99PheGlu: 1.99 ± 0.082
0.995PhePhe: 0.995 ± 0.755
2.985PheGly: 2.985 ± 0.59
0.0PheHis: 0.0 ± 0.0
1.99PheIle: 1.99 ± 0.082
0.0PheLys: 0.0 ± 0.0
5.97PheLeu: 5.97 ± 2.608
0.0PheMet: 0.0 ± 0.0
1.99PheAsn: 1.99 ± 1.51
3.98PhePro: 3.98 ± 2.691
2.985PheGln: 2.985 ± 0.837
3.98PheArg: 3.98 ± 0.165
4.975PheSer: 4.975 ± 0.92
4.975PheThr: 4.975 ± 0.508
2.985PheVal: 2.985 ± 0.837
0.995PheTrp: 0.995 ± 0.673
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
0.995GlyAla: 0.995 ± 0.673
0.0GlyCys: 0.0 ± 0.0
4.975GlyAsp: 4.975 ± 0.508
2.985GlyGlu: 2.985 ± 0.59
4.975GlyPhe: 4.975 ± 0.92
10.945GlyGly: 10.945 ± 4.023
0.995GlyHis: 0.995 ± 0.673
4.975GlyIle: 4.975 ± 2.348
2.985GlyLys: 2.985 ± 0.837
4.975GlyLeu: 4.975 ± 0.508
2.985GlyMet: 2.985 ± 2.018
2.985GlyAsn: 2.985 ± 2.265
2.985GlyPro: 2.985 ± 0.837
4.975GlyGln: 4.975 ± 2.348
6.965GlyArg: 6.965 ± 2.43
3.98GlySer: 3.98 ± 0.165
2.985GlyThr: 2.985 ± 0.837
1.99GlyVal: 1.99 ± 0.082
0.0GlyTrp: 0.0 ± 0.0
5.97GlyTyr: 5.97 ± 1.181
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.995HisAsp: 0.995 ± 0.673
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.995HisIle: 0.995 ± 0.673
0.0HisLys: 0.0 ± 0.0
1.99HisLeu: 1.99 ± 0.082
0.0HisMet: 0.0 ± 0.0
0.995HisAsn: 0.995 ± 0.673
0.995HisPro: 0.995 ± 0.673
0.0HisGln: 0.0 ± 0.0
1.99HisArg: 1.99 ± 1.345
0.995HisSer: 0.995 ± 0.755
0.995HisThr: 0.995 ± 0.673
0.995HisVal: 0.995 ± 0.673
0.0HisTrp: 0.0 ± 0.0
0.995HisTyr: 0.995 ± 0.673
0.0HisXaa: 0.0 ± 0.0
Ile
6.965IleAla: 6.965 ± 1.002
0.995IleCys: 0.995 ± 0.673
2.985IleAsp: 2.985 ± 0.59
0.995IleGlu: 0.995 ± 0.673
2.985IlePhe: 2.985 ± 0.59
1.99IleGly: 1.99 ± 0.082
0.0IleHis: 0.0 ± 0.0
2.985IleIle: 2.985 ± 0.59
4.975IleLys: 4.975 ± 0.508
4.975IleLeu: 4.975 ± 0.508
3.98IleMet: 3.98 ± 0.165
3.98IleAsn: 3.98 ± 2.691
6.965IlePro: 6.965 ± 1.002
2.985IleGln: 2.985 ± 0.837
5.97IleArg: 5.97 ± 4.036
6.965IleSer: 6.965 ± 1.002
5.97IleThr: 5.97 ± 0.247
0.995IleVal: 0.995 ± 0.673
0.0IleTrp: 0.0 ± 0.0
0.995IleTyr: 0.995 ± 0.755
0.0IleXaa: 0.0 ± 0.0
Lys
1.99LysAla: 1.99 ± 0.082
0.995LysCys: 0.995 ± 0.755
3.98LysAsp: 3.98 ± 1.593
0.995LysGlu: 0.995 ± 0.673
3.98LysPhe: 3.98 ± 0.165
1.99LysGly: 1.99 ± 0.082
0.995LysHis: 0.995 ± 0.673
5.97LysIle: 5.97 ± 1.181
5.97LysLys: 5.97 ± 3.103
0.995LysLeu: 0.995 ± 0.673
0.0LysMet: 0.0 ± 0.0
1.99LysAsn: 1.99 ± 1.51
3.98LysPro: 3.98 ± 0.165
0.995LysGln: 0.995 ± 0.755
2.985LysArg: 2.985 ± 2.018
3.98LysSer: 3.98 ± 1.263
3.98LysThr: 3.98 ± 0.165
2.985LysVal: 2.985 ± 0.837
1.99LysTrp: 1.99 ± 0.082
2.985LysTyr: 2.985 ± 0.59
0.0LysXaa: 0.0 ± 0.0
Leu
4.975LeuAla: 4.975 ± 0.92
0.0LeuCys: 0.0 ± 0.0
4.975LeuAsp: 4.975 ± 0.92
5.97LeuGlu: 5.97 ± 4.036
1.99LeuPhe: 1.99 ± 1.51
5.97LeuGly: 5.97 ± 1.181
0.995LeuHis: 0.995 ± 0.673
5.97LeuIle: 5.97 ± 2.608
5.97LeuLys: 5.97 ± 4.036
3.98LeuLeu: 3.98 ± 3.02
0.995LeuMet: 0.995 ± 0.755
0.0LeuAsn: 0.0 ± 0.0
8.955LeuPro: 8.955 ± 0.343
2.985LeuGln: 2.985 ± 0.59
2.985LeuArg: 2.985 ± 0.59
3.98LeuSer: 3.98 ± 1.593
3.98LeuThr: 3.98 ± 3.02
2.985LeuVal: 2.985 ± 0.837
1.99LeuTrp: 1.99 ± 0.082
0.995LeuTyr: 0.995 ± 0.673
0.0LeuXaa: 0.0 ± 0.0
Met
1.99MetAla: 1.99 ± 1.345
0.0MetCys: 0.0 ± 0.0
0.995MetAsp: 0.995 ± 0.673
1.99MetGlu: 1.99 ± 1.51
0.995MetPhe: 0.995 ± 0.755
0.995MetGly: 0.995 ± 0.755
0.0MetHis: 0.0 ± 0.0
1.99MetIle: 1.99 ± 0.082
0.995MetLys: 0.995 ± 0.673
0.995MetLeu: 0.995 ± 0.673
0.995MetMet: 0.995 ± 0.755
0.995MetAsn: 0.995 ± 0.673
2.985MetPro: 2.985 ± 2.018
0.0MetGln: 0.0 ± 0.0
2.985MetArg: 2.985 ± 0.837
1.99MetSer: 1.99 ± 1.345
0.995MetThr: 0.995 ± 0.673
2.985MetVal: 2.985 ± 0.837
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.99AsnAla: 1.99 ± 1.51
0.0AsnCys: 0.0 ± 0.0
1.99AsnAsp: 1.99 ± 1.51
3.98AsnGlu: 3.98 ± 1.263
0.0AsnPhe: 0.0 ± 0.0
2.985AsnGly: 2.985 ± 0.59
0.995AsnHis: 0.995 ± 0.755
5.97AsnIle: 5.97 ± 1.181
2.985AsnLys: 2.985 ± 0.59
3.98AsnLeu: 3.98 ± 1.263
0.995AsnMet: 0.995 ± 0.673
0.0AsnAsn: 0.0 ± 0.0
1.99AsnPro: 1.99 ± 1.51
0.995AsnGln: 0.995 ± 0.755
0.0AsnArg: 0.0 ± 0.0
1.99AsnSer: 1.99 ± 0.082
0.995AsnThr: 0.995 ± 0.673
2.985AsnVal: 2.985 ± 0.837
0.995AsnTrp: 0.995 ± 0.673
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
8.955ProAla: 8.955 ± 5.368
0.995ProCys: 0.995 ± 0.755
3.98ProAsp: 3.98 ± 2.691
7.96ProGlu: 7.96 ± 0.33
4.975ProPhe: 4.975 ± 0.508
1.99ProGly: 1.99 ± 0.082
0.995ProHis: 0.995 ± 0.755
0.995ProIle: 0.995 ± 0.673
2.985ProLys: 2.985 ± 0.837
4.975ProLeu: 4.975 ± 1.936
1.99ProMet: 1.99 ± 0.082
2.985ProAsn: 2.985 ± 0.59
9.95ProPro: 9.95 ± 1.84
0.995ProGln: 0.995 ± 0.755
4.975ProArg: 4.975 ± 0.92
3.98ProSer: 3.98 ± 2.691
2.985ProThr: 2.985 ± 0.837
7.96ProVal: 7.96 ± 1.098
3.98ProTrp: 3.98 ± 1.263
1.99ProTyr: 1.99 ± 0.082
0.0ProXaa: 0.0 ± 0.0
Gln
0.995GlnAla: 0.995 ± 0.755
0.0GlnCys: 0.0 ± 0.0
0.995GlnAsp: 0.995 ± 0.755
1.99GlnGlu: 1.99 ± 0.082
2.985GlnPhe: 2.985 ± 0.59
0.0GlnGly: 0.0 ± 0.0
0.995GlnHis: 0.995 ± 0.673
0.995GlnIle: 0.995 ± 0.673
2.985GlnLys: 2.985 ± 2.265
3.98GlnLeu: 3.98 ± 1.593
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
0.995GlnGln: 0.995 ± 0.673
1.99GlnArg: 1.99 ± 1.345
2.985GlnSer: 2.985 ± 0.837
5.97GlnThr: 5.97 ± 1.675
0.995GlnVal: 0.995 ± 0.755
0.0GlnTrp: 0.0 ± 0.0
3.98GlnTyr: 3.98 ± 3.02
0.0GlnXaa: 0.0 ± 0.0
Arg
6.965ArgAla: 6.965 ± 0.425
1.99ArgCys: 1.99 ± 1.345
4.975ArgAsp: 4.975 ± 3.363
0.995ArgGlu: 0.995 ± 0.673
3.98ArgPhe: 3.98 ± 1.263
13.93ArgGly: 13.93 ± 4.86
0.0ArgHis: 0.0 ± 0.0
3.98ArgIle: 3.98 ± 0.165
2.985ArgLys: 2.985 ± 0.59
2.985ArgLeu: 2.985 ± 0.59
2.985ArgMet: 2.985 ± 0.59
0.995ArgAsn: 0.995 ± 0.673
0.995ArgPro: 0.995 ± 0.673
0.995ArgGln: 0.995 ± 0.755
5.97ArgArg: 5.97 ± 0.247
4.975ArgSer: 4.975 ± 0.92
0.995ArgThr: 0.995 ± 0.755
0.995ArgVal: 0.995 ± 0.673
0.995ArgTrp: 0.995 ± 0.673
3.98ArgTyr: 3.98 ± 1.263
0.0ArgXaa: 0.0 ± 0.0
Ser
4.975SerAla: 4.975 ± 3.775
1.99SerCys: 1.99 ± 0.082
5.97SerAsp: 5.97 ± 0.247
0.995SerGlu: 0.995 ± 0.673
3.98SerPhe: 3.98 ± 0.165
6.965SerGly: 6.965 ± 1.002
1.99SerHis: 1.99 ± 1.345
4.975SerIle: 4.975 ± 1.936
0.995SerLys: 0.995 ± 0.673
8.955SerLeu: 8.955 ± 1.085
1.99SerMet: 1.99 ± 0.082
2.985SerAsn: 2.985 ± 0.59
3.98SerPro: 3.98 ± 1.593
1.99SerGln: 1.99 ± 1.51
0.995SerArg: 0.995 ± 0.755
3.98SerSer: 3.98 ± 1.263
3.98SerThr: 3.98 ± 0.165
1.99SerVal: 1.99 ± 1.345
1.99SerTrp: 1.99 ± 0.082
3.98SerTyr: 3.98 ± 0.165
0.0SerXaa: 0.0 ± 0.0
Thr
5.97ThrAla: 5.97 ± 1.675
0.995ThrCys: 0.995 ± 0.755
2.985ThrAsp: 2.985 ± 0.837
3.98ThrGlu: 3.98 ± 0.165
0.995ThrPhe: 0.995 ± 0.755
2.985ThrGly: 2.985 ± 0.59
0.995ThrHis: 0.995 ± 0.673
0.995ThrIle: 0.995 ± 0.673
7.96ThrLys: 7.96 ± 3.185
1.99ThrLeu: 1.99 ± 1.51
1.99ThrMet: 1.99 ± 0.082
1.99ThrAsn: 1.99 ± 1.345
5.97ThrPro: 5.97 ± 1.181
0.995ThrGln: 0.995 ± 0.755
3.98ThrArg: 3.98 ± 1.263
2.985ThrSer: 2.985 ± 0.837
3.98ThrThr: 3.98 ± 0.165
1.99ThrVal: 1.99 ± 1.51
0.0ThrTrp: 0.0 ± 0.0
1.99ThrTyr: 1.99 ± 0.082
0.0ThrXaa: 0.0 ± 0.0
Val
2.985ValAla: 2.985 ± 0.837
0.995ValCys: 0.995 ± 0.673
4.975ValAsp: 4.975 ± 1.936
1.99ValGlu: 1.99 ± 1.51
4.975ValPhe: 4.975 ± 0.508
2.985ValGly: 2.985 ± 0.837
0.0ValHis: 0.0 ± 0.0
2.985ValIle: 2.985 ± 2.265
0.0ValLys: 0.0 ± 0.0
2.985ValLeu: 2.985 ± 0.59
0.0ValMet: 0.0 ± 0.0
0.995ValAsn: 0.995 ± 0.673
6.965ValPro: 6.965 ± 2.43
0.995ValGln: 0.995 ± 0.673
1.99ValArg: 1.99 ± 0.082
2.985ValSer: 2.985 ± 0.837
2.985ValThr: 2.985 ± 0.59
2.985ValVal: 2.985 ± 2.018
1.99ValTrp: 1.99 ± 1.345
3.98ValTyr: 3.98 ± 2.691
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.995TrpGlu: 0.995 ± 0.673
1.99TrpPhe: 1.99 ± 1.345
0.995TrpGly: 0.995 ± 0.673
0.995TrpHis: 0.995 ± 0.673
2.985TrpIle: 2.985 ± 0.59
1.99TrpLys: 1.99 ± 1.345
0.995TrpLeu: 0.995 ± 0.673
0.0TrpMet: 0.0 ± 0.0
1.99TrpAsn: 1.99 ± 1.51
0.0TrpPro: 0.0 ± 0.0
0.995TrpGln: 0.995 ± 0.673
0.995TrpArg: 0.995 ± 0.755
2.985TrpSer: 2.985 ± 0.59
0.0TrpThr: 0.0 ± 0.0
0.995TrpVal: 0.995 ± 0.755
0.995TrpTrp: 0.995 ± 0.755
0.995TrpTyr: 0.995 ± 0.673
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.985TyrAla: 2.985 ± 2.018
0.0TyrCys: 0.0 ± 0.0
0.995TyrAsp: 0.995 ± 0.755
1.99TyrGlu: 1.99 ± 0.082
0.995TyrPhe: 0.995 ± 0.673
4.975TyrGly: 4.975 ± 1.936
1.99TyrHis: 1.99 ± 1.345
3.98TyrIle: 3.98 ± 1.593
0.995TyrLys: 0.995 ± 0.673
1.99TyrLeu: 1.99 ± 0.082
0.995TyrMet: 0.995 ± 0.755
2.985TyrAsn: 2.985 ± 0.59
5.97TyrPro: 5.97 ± 2.608
2.985TyrGln: 2.985 ± 0.837
2.985TyrArg: 2.985 ± 0.837
0.0TyrSer: 0.0 ± 0.0
1.99TyrThr: 1.99 ± 1.345
1.99TyrVal: 1.99 ± 0.082
0.0TyrTrp: 0.0 ± 0.0
2.985TyrTyr: 2.985 ± 0.59
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1006 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski