Amino acid dipepetide frequency for Bovine polyomavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.961AlaAla: 5.961 ± 1.806
0.497AlaCys: 0.497 ± 0.565
2.981AlaAsp: 2.981 ± 0.611
7.948AlaGlu: 7.948 ± 2.703
1.987AlaPhe: 1.987 ± 1.059
4.471AlaGly: 4.471 ± 1.098
1.987AlaHis: 1.987 ± 0.669
2.981AlaIle: 2.981 ± 1.023
5.961AlaLys: 5.961 ± 1.085
6.955AlaLeu: 6.955 ± 3.065
0.497AlaMet: 0.497 ± 0.473
2.981AlaAsn: 2.981 ± 1.095
3.477AlaPro: 3.477 ± 1.118
2.981AlaGln: 2.981 ± 0.46
2.981AlaArg: 2.981 ± 0.46
2.484AlaSer: 2.484 ± 1.039
2.981AlaThr: 2.981 ± 1.372
4.968AlaVal: 4.968 ± 0.631
0.497AlaTrp: 0.497 ± 0.317
1.49AlaTyr: 1.49 ± 0.547
0.0AlaXaa: 0.0 ± 0.0
Cys
0.994CysAla: 0.994 ± 0.634
0.497CysCys: 0.497 ± 0.317
2.484CysAsp: 2.484 ± 0.767
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.994CysGly: 0.994 ± 0.946
0.497CysHis: 0.497 ± 0.317
2.484CysIle: 2.484 ± 1.124
2.484CysLys: 2.484 ± 1.57
3.974CysLeu: 3.974 ± 1.488
0.497CysMet: 0.497 ± 0.349
0.994CysAsn: 0.994 ± 0.401
1.987CysPro: 1.987 ± 0.799
0.497CysGln: 0.497 ± 0.317
0.994CysArg: 0.994 ± 0.792
0.497CysSer: 0.497 ± 0.317
0.994CysThr: 0.994 ± 0.536
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
2.484CysTyr: 2.484 ± 1.541
0.0CysXaa: 0.0 ± 0.0
Asp
1.49AspAla: 1.49 ± 0.616
0.0AspCys: 0.0 ± 0.0
1.49AspAsp: 1.49 ± 0.951
2.484AspGlu: 2.484 ± 0.79
2.981AspPhe: 2.981 ± 1.541
4.471AspGly: 4.471 ± 1.361
0.994AspHis: 0.994 ± 0.634
1.49AspIle: 1.49 ± 0.479
2.981AspLys: 2.981 ± 0.861
5.961AspLeu: 5.961 ± 0.62
0.994AspMet: 0.994 ± 0.593
0.994AspAsn: 0.994 ± 0.401
5.464AspPro: 5.464 ± 1.907
0.0AspGln: 0.0 ± 0.0
0.994AspArg: 0.994 ± 0.655
7.452AspSer: 7.452 ± 1.212
1.987AspThr: 1.987 ± 0.85
2.484AspVal: 2.484 ± 0.846
1.49AspTrp: 1.49 ± 0.778
0.497AspTyr: 0.497 ± 0.317
0.0AspXaa: 0.0 ± 0.0
Glu
4.968GluAla: 4.968 ± 2.302
0.497GluCys: 0.497 ± 0.396
3.974GluAsp: 3.974 ± 1.283
4.471GluGlu: 4.471 ± 1.57
2.981GluPhe: 2.981 ± 1.089
1.49GluGly: 1.49 ± 0.818
1.987GluHis: 1.987 ± 1.072
4.471GluIle: 4.471 ± 1.024
6.955GluLys: 6.955 ± 2.144
3.974GluLeu: 3.974 ± 1.046
0.994GluMet: 0.994 ± 0.717
3.974GluAsn: 3.974 ± 1.442
4.471GluPro: 4.471 ± 1.45
2.484GluGln: 2.484 ± 1.543
3.477GluArg: 3.477 ± 1.583
4.968GluSer: 4.968 ± 0.877
2.981GluThr: 2.981 ± 0.555
4.471GluVal: 4.471 ± 1.584
0.0GluTrp: 0.0 ± 0.0
1.49GluTyr: 1.49 ± 0.651
0.0GluXaa: 0.0 ± 0.0
Phe
4.471PheAla: 4.471 ± 1.377
0.994PheCys: 0.994 ± 0.634
1.987PheAsp: 1.987 ± 0.94
2.981PheGlu: 2.981 ± 1.089
1.987PhePhe: 1.987 ± 0.782
1.49PheGly: 1.49 ± 0.479
0.994PheHis: 0.994 ± 0.401
1.987PheIle: 1.987 ± 0.477
3.974PheLys: 3.974 ± 1.089
2.484PheLeu: 2.484 ± 0.536
0.0PheMet: 0.0 ± 0.0
2.981PheAsn: 2.981 ± 0.827
2.484PhePro: 2.484 ± 1.236
2.484PheGln: 2.484 ± 0.648
0.497PheArg: 0.497 ± 0.317
4.471PheSer: 4.471 ± 0.976
2.981PheThr: 2.981 ± 0.732
0.0PheVal: 0.0 ± 0.0
0.497PheTrp: 0.497 ± 0.396
1.987PheTyr: 1.987 ± 0.603
0.0PheXaa: 0.0 ± 0.0
Gly
6.955GlyAla: 6.955 ± 1.889
0.497GlyCys: 0.497 ± 0.317
3.974GlyAsp: 3.974 ± 0.824
3.974GlyGlu: 3.974 ± 1.505
2.981GlyPhe: 2.981 ± 1.457
6.458GlyGly: 6.458 ± 1.024
0.0GlyHis: 0.0 ± 0.0
5.961GlyIle: 5.961 ± 1.809
3.477GlyLys: 3.477 ± 1.129
7.452GlyLeu: 7.452 ± 2.589
0.0GlyMet: 0.0 ± 0.0
2.484GlyAsn: 2.484 ± 0.648
3.974GlyPro: 3.974 ± 0.812
1.987GlyGln: 1.987 ± 0.49
4.968GlyArg: 4.968 ± 1.844
5.464GlySer: 5.464 ± 1.502
2.484GlyThr: 2.484 ± 0.686
2.981GlyVal: 2.981 ± 1.095
0.0GlyTrp: 0.0 ± 0.0
0.994GlyTyr: 0.994 ± 0.946
0.0GlyXaa: 0.0 ± 0.0
His
0.994HisAla: 0.994 ± 0.401
0.994HisCys: 0.994 ± 0.445
0.0HisAsp: 0.0 ± 0.0
0.497HisGlu: 0.497 ± 0.317
0.497HisPhe: 0.497 ± 0.317
0.994HisGly: 0.994 ± 0.634
1.49HisHis: 1.49 ± 0.664
0.0HisIle: 0.0 ± 0.0
1.987HisLys: 1.987 ± 0.91
2.484HisLeu: 2.484 ± 1.669
1.49HisMet: 1.49 ± 0.818
2.981HisAsn: 2.981 ± 1.233
1.987HisPro: 1.987 ± 0.73
1.49HisGln: 1.49 ± 1.012
1.49HisArg: 1.49 ± 0.951
0.994HisSer: 0.994 ± 0.634
0.0HisThr: 0.0 ± 0.0
0.497HisVal: 0.497 ± 0.317
0.0HisTrp: 0.0 ± 0.0
0.497HisTyr: 0.497 ± 0.317
0.0HisXaa: 0.0 ± 0.0
Ile
1.987IleAla: 1.987 ± 0.65
1.49IleCys: 1.49 ± 1.054
1.987IleAsp: 1.987 ± 0.603
5.464IleGlu: 5.464 ± 1.175
2.981IlePhe: 2.981 ± 0.46
2.484IleGly: 2.484 ± 0.517
1.49IleHis: 1.49 ± 0.616
1.987IleIle: 1.987 ± 1.134
1.987IleLys: 1.987 ± 0.983
5.961IleLeu: 5.961 ± 1.396
0.994IleMet: 0.994 ± 0.634
1.987IleAsn: 1.987 ± 0.603
4.968IlePro: 4.968 ± 1.452
1.49IleGln: 1.49 ± 0.915
0.994IleArg: 0.994 ± 0.401
4.968IleSer: 4.968 ± 2.352
2.981IleThr: 2.981 ± 0.732
2.484IleVal: 2.484 ± 0.536
0.994IleTrp: 0.994 ± 0.445
0.994IleTyr: 0.994 ± 0.401
0.0IleXaa: 0.0 ± 0.0
Lys
4.968LysAla: 4.968 ± 1.265
1.49LysCys: 1.49 ± 0.664
2.981LysAsp: 2.981 ± 0.861
1.49LysGlu: 1.49 ± 0.479
3.974LysPhe: 3.974 ± 1.377
5.464LysGly: 5.464 ± 0.947
2.484LysHis: 2.484 ± 1.183
4.471LysIle: 4.471 ± 1.813
2.981LysLys: 2.981 ± 1.327
4.968LysLeu: 4.968 ± 1.766
1.987LysMet: 1.987 ± 0.823
4.471LysAsn: 4.471 ± 1.361
2.981LysPro: 2.981 ± 1.072
1.987LysGln: 1.987 ± 0.49
4.471LysArg: 4.471 ± 0.991
2.484LysSer: 2.484 ± 1.086
4.471LysThr: 4.471 ± 1.362
2.484LysVal: 2.484 ± 0.906
1.49LysTrp: 1.49 ± 0.813
1.987LysTyr: 1.987 ± 0.782
0.0LysXaa: 0.0 ± 0.0
Leu
3.974LeuAla: 3.974 ± 1.143
3.974LeuCys: 3.974 ± 0.864
4.471LeuAsp: 4.471 ± 1.361
7.948LeuGlu: 7.948 ± 1.606
2.981LeuPhe: 2.981 ± 1.034
5.464LeuGly: 5.464 ± 1.782
0.497LeuHis: 0.497 ± 0.565
7.948LeuIle: 7.948 ± 1.275
3.477LeuLys: 3.477 ± 1.439
13.413LeuLeu: 13.413 ± 0.87
0.994LeuMet: 0.994 ± 0.655
5.464LeuAsn: 5.464 ± 1.178
3.974LeuPro: 3.974 ± 2.039
5.464LeuGln: 5.464 ± 1.302
4.471LeuArg: 4.471 ± 0.984
9.935LeuSer: 9.935 ± 1.838
4.471LeuThr: 4.471 ± 1.058
4.471LeuVal: 4.471 ± 1.984
1.49LeuTrp: 1.49 ± 0.781
2.484LeuTyr: 2.484 ± 0.767
0.0LeuXaa: 0.0 ± 0.0
Met
2.484MetAla: 2.484 ± 0.686
0.994MetCys: 0.994 ± 0.445
0.994MetAsp: 0.994 ± 0.445
0.994MetGlu: 0.994 ± 0.655
0.994MetPhe: 0.994 ± 0.401
1.987MetGly: 1.987 ± 1.251
0.994MetHis: 0.994 ± 0.445
0.497MetIle: 0.497 ± 0.317
1.49MetLys: 1.49 ± 0.479
0.497MetLeu: 0.497 ± 0.473
1.49MetMet: 1.49 ± 0.651
0.497MetAsn: 0.497 ± 0.565
0.497MetPro: 0.497 ± 0.473
0.0MetGln: 0.0 ± 0.0
0.497MetArg: 0.497 ± 0.565
0.0MetSer: 0.0 ± 0.0
2.484MetThr: 2.484 ± 1.162
0.994MetVal: 0.994 ± 0.445
0.994MetTrp: 0.994 ± 0.655
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.49AsnAla: 1.49 ± 0.547
1.987AsnCys: 1.987 ± 0.94
1.49AsnAsp: 1.49 ± 0.616
3.974AsnGlu: 3.974 ± 1.599
2.484AsnPhe: 2.484 ± 0.648
2.981AsnGly: 2.981 ± 1.262
0.0AsnHis: 0.0 ± 0.0
2.981AsnIle: 2.981 ± 0.793
3.477AsnLys: 3.477 ± 1.362
2.484AsnLeu: 2.484 ± 0.669
0.497AsnMet: 0.497 ± 0.317
0.497AsnAsn: 0.497 ± 0.317
2.484AsnPro: 2.484 ± 1.212
2.981AsnGln: 2.981 ± 1.192
1.987AsnArg: 1.987 ± 0.971
3.477AsnSer: 3.477 ± 0.987
1.987AsnThr: 1.987 ± 0.782
1.49AsnVal: 1.49 ± 0.527
0.994AsnTrp: 0.994 ± 0.717
2.981AsnTyr: 2.981 ± 0.877
0.0AsnXaa: 0.0 ± 0.0
Pro
3.477ProAla: 3.477 ± 0.43
2.484ProCys: 2.484 ± 1.199
4.968ProAsp: 4.968 ± 1.351
2.981ProGlu: 2.981 ± 1.426
1.987ProPhe: 1.987 ± 0.669
3.974ProGly: 3.974 ± 0.7
1.49ProHis: 1.49 ± 0.651
2.981ProIle: 2.981 ± 1.072
4.471ProLys: 4.471 ± 3.014
3.974ProLeu: 3.974 ± 0.419
2.484ProMet: 2.484 ± 1.278
2.981ProAsn: 2.981 ± 1.362
6.458ProPro: 6.458 ± 4.149
3.974ProGln: 3.974 ± 2.625
4.968ProArg: 4.968 ± 3.027
4.471ProSer: 4.471 ± 1.362
3.477ProThr: 3.477 ± 1.272
3.477ProVal: 3.477 ± 2.254
0.497ProTrp: 0.497 ± 0.565
0.497ProTyr: 0.497 ± 0.473
0.0ProXaa: 0.0 ± 0.0
Gln
2.484GlnAla: 2.484 ± 1.299
0.497GlnCys: 0.497 ± 0.396
2.981GlnAsp: 2.981 ± 1.301
3.477GlnGlu: 3.477 ± 1.561
2.484GlnPhe: 2.484 ± 0.891
3.477GlnGly: 3.477 ± 1.118
2.981GlnHis: 2.981 ± 0.66
1.49GlnIle: 1.49 ± 0.483
2.484GlnLys: 2.484 ± 0.904
3.477GlnLeu: 3.477 ± 0.43
1.987GlnMet: 1.987 ± 0.971
0.994GlnAsn: 0.994 ± 0.717
3.974GlnPro: 3.974 ± 2.268
2.484GlnGln: 2.484 ± 0.767
1.987GlnArg: 1.987 ± 1.34
1.987GlnSer: 1.987 ± 0.669
2.981GlnThr: 2.981 ± 0.801
1.49GlnVal: 1.49 ± 0.771
0.0GlnTrp: 0.0 ± 0.0
1.987GlnTyr: 1.987 ± 0.642
0.0GlnXaa: 0.0 ± 0.0
Arg
3.974ArgAla: 3.974 ± 1.285
0.994ArgCys: 0.994 ± 0.792
0.497ArgAsp: 0.497 ± 0.473
5.464ArgGlu: 5.464 ± 1.632
1.987ArgPhe: 1.987 ± 0.799
1.49ArgGly: 1.49 ± 0.479
0.497ArgHis: 0.497 ± 0.317
1.49ArgIle: 1.49 ± 0.483
3.477ArgLys: 3.477 ± 1.333
5.464ArgLeu: 5.464 ± 2.616
1.49ArgMet: 1.49 ± 1.127
1.49ArgAsn: 1.49 ± 0.676
2.484ArgPro: 2.484 ± 2.206
2.484ArgGln: 2.484 ± 1.669
1.49ArgArg: 1.49 ± 0.483
2.981ArgSer: 2.981 ± 0.801
2.981ArgThr: 2.981 ± 0.732
1.987ArgVal: 1.987 ± 1.275
0.994ArgTrp: 0.994 ± 0.717
1.49ArgTyr: 1.49 ± 1.419
0.0ArgXaa: 0.0 ± 0.0
Ser
5.961SerAla: 5.961 ± 0.939
0.497SerCys: 0.497 ± 0.317
2.981SerAsp: 2.981 ± 0.611
1.49SerGlu: 1.49 ± 0.951
2.981SerPhe: 2.981 ± 1.034
7.948SerGly: 7.948 ± 2.035
1.987SerHis: 1.987 ± 0.555
3.477SerIle: 3.477 ± 0.476
1.987SerLys: 1.987 ± 0.94
8.445SerLeu: 8.445 ± 2.118
1.987SerMet: 1.987 ± 0.693
1.987SerAsn: 1.987 ± 0.603
3.974SerPro: 3.974 ± 1.188
4.471SerGln: 4.471 ± 0.976
5.961SerArg: 5.961 ± 2.355
7.452SerSer: 7.452 ± 2.27
7.452SerThr: 7.452 ± 2.115
6.955SerVal: 6.955 ± 2.99
0.497SerTrp: 0.497 ± 0.317
3.477SerTyr: 3.477 ± 0.987
0.0SerXaa: 0.0 ± 0.0
Thr
5.464ThrAla: 5.464 ± 2.245
0.497ThrCys: 0.497 ± 0.473
2.981ThrAsp: 2.981 ± 0.877
1.987ThrGlu: 1.987 ± 0.803
0.994ThrPhe: 0.994 ± 0.445
3.974ThrGly: 3.974 ± 0.891
0.0ThrHis: 0.0 ± 0.0
2.981ThrIle: 2.981 ± 1.262
2.484ThrLys: 2.484 ± 0.767
6.458ThrLeu: 6.458 ± 1.756
0.0ThrMet: 0.0 ± 0.0
0.497ThrAsn: 0.497 ± 0.473
5.961ThrPro: 5.961 ± 1.426
4.968ThrGln: 4.968 ± 0.899
0.497ThrArg: 0.497 ± 0.565
6.955ThrSer: 6.955 ± 2.976
3.477ThrThr: 3.477 ± 0.824
3.477ThrVal: 3.477 ± 1.165
2.484ThrTrp: 2.484 ± 0.648
1.49ThrTyr: 1.49 ± 0.818
0.0ThrXaa: 0.0 ± 0.0
Val
2.981ValAla: 2.981 ± 0.87
1.49ValCys: 1.49 ± 0.997
1.987ValAsp: 1.987 ± 0.603
4.968ValGlu: 4.968 ± 2.528
1.49ValPhe: 1.49 ± 0.951
3.477ValGly: 3.477 ± 1.53
0.0ValHis: 0.0 ± 0.0
0.497ValIle: 0.497 ± 0.565
4.471ValLys: 4.471 ± 1.361
3.974ValLeu: 3.974 ± 1.117
0.497ValMet: 0.497 ± 0.574
4.471ValAsn: 4.471 ± 0.976
1.987ValPro: 1.987 ± 1.658
0.994ValGln: 0.994 ± 0.655
0.497ValArg: 0.497 ± 0.473
5.961ValSer: 5.961 ± 0.639
3.477ValThr: 3.477 ± 0.671
2.981ValVal: 2.981 ± 0.46
0.994ValTrp: 0.994 ± 0.401
2.484ValTyr: 2.484 ± 0.711
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.994TrpAsp: 0.994 ± 0.717
0.994TrpGlu: 0.994 ± 0.593
0.497TrpPhe: 0.497 ± 0.396
1.49TrpGly: 1.49 ± 0.778
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.49TrpLys: 1.49 ± 0.616
1.49TrpLeu: 1.49 ± 0.616
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.497TrpArg: 0.497 ± 0.473
1.49TrpSer: 1.49 ± 0.616
1.987TrpThr: 1.987 ± 0.555
0.497TrpVal: 0.497 ± 0.565
0.497TrpTrp: 0.497 ± 0.317
2.484TrpTyr: 2.484 ± 0.648
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.987TyrAla: 1.987 ± 1.434
2.981TyrCys: 2.981 ± 1.335
0.497TyrAsp: 0.497 ± 0.473
1.49TyrGlu: 1.49 ± 0.951
2.484TyrPhe: 2.484 ± 0.891
2.484TyrGly: 2.484 ± 0.79
0.994TyrHis: 0.994 ± 0.445
0.497TyrIle: 0.497 ± 0.473
2.484TyrLys: 2.484 ± 1.278
3.477TyrLeu: 3.477 ± 1.142
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.484TyrPro: 2.484 ± 1.515
2.484TyrGln: 2.484 ± 1.208
1.49TyrArg: 1.49 ± 0.664
3.477TyrSer: 3.477 ± 1.158
0.994TyrThr: 0.994 ± 0.401
1.49TyrVal: 1.49 ± 0.616
0.0TyrTrp: 0.0 ± 0.0
0.994TyrTyr: 0.994 ± 0.946
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2014 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski