Amino acid dipepetide frequency for Rousettus aegyptiacus adenovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.01AlaAla: 5.01 ± 0.786
0.978AlaCys: 0.978 ± 0.457
2.933AlaAsp: 2.933 ± 0.746
3.788AlaGlu: 3.788 ± 0.582
3.177AlaPhe: 3.177 ± 0.611
3.055AlaGly: 3.055 ± 0.889
0.855AlaHis: 0.855 ± 0.471
3.299AlaIle: 3.299 ± 0.532
2.81AlaLys: 2.81 ± 0.632
6.109AlaLeu: 6.109 ± 0.755
1.1AlaMet: 1.1 ± 0.305
4.521AlaAsn: 4.521 ± 0.569
3.788AlaPro: 3.788 ± 0.739
3.055AlaGln: 3.055 ± 0.521
2.566AlaArg: 2.566 ± 0.612
3.421AlaSer: 3.421 ± 0.66
2.81AlaThr: 2.81 ± 0.457
4.032AlaVal: 4.032 ± 0.789
0.855AlaTrp: 0.855 ± 0.351
2.81AlaTyr: 2.81 ± 0.563
0.0AlaXaa: 0.0 ± 0.0
Cys
0.611CysAla: 0.611 ± 0.296
0.733CysCys: 0.733 ± 0.291
1.222CysAsp: 1.222 ± 0.509
0.855CysGlu: 0.855 ± 0.473
0.978CysPhe: 0.978 ± 0.327
1.1CysGly: 1.1 ± 0.428
0.244CysHis: 0.244 ± 0.175
0.489CysIle: 0.489 ± 0.277
1.1CysLys: 1.1 ± 0.482
0.978CysLeu: 0.978 ± 0.4
1.1CysMet: 1.1 ± 0.334
1.588CysAsn: 1.588 ± 0.475
1.1CysPro: 1.1 ± 0.369
0.367CysGln: 0.367 ± 0.225
0.733CysArg: 0.733 ± 0.424
0.978CysSer: 0.978 ± 0.314
0.733CysThr: 0.733 ± 0.428
1.1CysVal: 1.1 ± 0.41
0.367CysTrp: 0.367 ± 0.247
0.611CysTyr: 0.611 ± 0.294
0.0CysXaa: 0.0 ± 0.0
Asp
1.588AspAla: 1.588 ± 0.373
0.733AspCys: 0.733 ± 0.238
2.077AspAsp: 2.077 ± 0.761
4.399AspGlu: 4.399 ± 0.767
3.055AspPhe: 3.055 ± 0.628
2.81AspGly: 2.81 ± 1.078
0.367AspHis: 0.367 ± 0.177
3.788AspIle: 3.788 ± 0.525
2.566AspLys: 2.566 ± 0.408
3.788AspLeu: 3.788 ± 0.753
0.855AspMet: 0.855 ± 0.288
3.91AspAsn: 3.91 ± 0.511
1.955AspPro: 1.955 ± 0.578
1.955AspGln: 1.955 ± 0.382
1.955AspArg: 1.955 ± 0.614
1.955AspSer: 1.955 ± 0.426
2.322AspThr: 2.322 ± 0.486
3.177AspVal: 3.177 ± 0.45
0.489AspTrp: 0.489 ± 0.243
1.466AspTyr: 1.466 ± 0.364
0.0AspXaa: 0.0 ± 0.0
Glu
3.299GluAla: 3.299 ± 0.66
0.978GluCys: 0.978 ± 0.35
3.421GluAsp: 3.421 ± 0.639
7.576GluGlu: 7.576 ± 1.422
1.955GluPhe: 1.955 ± 0.407
3.177GluGly: 3.177 ± 0.794
0.733GluHis: 0.733 ± 0.301
4.765GluIle: 4.765 ± 0.762
3.177GluLys: 3.177 ± 0.748
4.277GluLeu: 4.277 ± 0.792
1.344GluMet: 1.344 ± 0.425
2.933GluAsn: 2.933 ± 0.434
2.444GluPro: 2.444 ± 0.511
1.955GluGln: 1.955 ± 0.521
3.299GluArg: 3.299 ± 0.86
4.643GluSer: 4.643 ± 0.925
4.277GluThr: 4.277 ± 0.804
4.032GluVal: 4.032 ± 0.69
0.733GluTrp: 0.733 ± 0.243
2.566GluTyr: 2.566 ± 0.5
0.0GluXaa: 0.0 ± 0.0
Phe
2.322PheAla: 2.322 ± 0.47
0.611PheCys: 0.611 ± 0.321
2.566PheAsp: 2.566 ± 0.615
2.81PheGlu: 2.81 ± 0.768
2.566PhePhe: 2.566 ± 0.551
1.711PheGly: 1.711 ± 0.452
0.733PheHis: 0.733 ± 0.215
2.933PheIle: 2.933 ± 0.557
3.421PheLys: 3.421 ± 0.758
5.376PheLeu: 5.376 ± 0.909
1.344PheMet: 1.344 ± 0.257
3.055PheAsn: 3.055 ± 0.343
2.322PhePro: 2.322 ± 0.509
1.466PheGln: 1.466 ± 0.306
3.177PheArg: 3.177 ± 0.794
3.299PheSer: 3.299 ± 0.73
2.444PheThr: 2.444 ± 0.477
3.177PheVal: 3.177 ± 0.439
0.0PheTrp: 0.0 ± 0.0
1.711PheTyr: 1.711 ± 0.315
0.0PheXaa: 0.0 ± 0.0
Gly
3.666GlyAla: 3.666 ± 0.713
0.733GlyCys: 0.733 ± 0.26
2.199GlyAsp: 2.199 ± 0.463
2.933GlyGlu: 2.933 ± 0.616
2.444GlyPhe: 2.444 ± 0.448
3.788GlyGly: 3.788 ± 0.983
1.344GlyHis: 1.344 ± 0.348
3.299GlyIle: 3.299 ± 0.681
3.177GlyLys: 3.177 ± 0.757
5.01GlyLeu: 5.01 ± 1.667
0.978GlyMet: 0.978 ± 0.384
2.688GlyAsn: 2.688 ± 0.874
2.444GlyPro: 2.444 ± 0.4
1.955GlyGln: 1.955 ± 0.62
3.421GlyArg: 3.421 ± 0.661
5.01GlySer: 5.01 ± 0.793
3.666GlyThr: 3.666 ± 0.766
3.788GlyVal: 3.788 ± 0.562
0.611GlyTrp: 0.611 ± 0.21
1.222GlyTyr: 1.222 ± 0.325
0.0GlyXaa: 0.0 ± 0.0
His
1.344HisAla: 1.344 ± 0.389
0.733HisCys: 0.733 ± 0.451
0.855HisAsp: 0.855 ± 0.348
0.244HisGlu: 0.244 ± 0.15
0.733HisPhe: 0.733 ± 0.269
1.222HisGly: 1.222 ± 0.316
0.489HisHis: 0.489 ± 0.171
1.222HisIle: 1.222 ± 0.322
0.611HisLys: 0.611 ± 0.277
2.199HisLeu: 2.199 ± 0.499
0.122HisMet: 0.122 ± 0.111
1.344HisAsn: 1.344 ± 0.411
1.833HisPro: 1.833 ± 0.413
0.611HisGln: 0.611 ± 0.174
0.978HisArg: 0.978 ± 0.267
1.1HisSer: 1.1 ± 0.442
1.344HisThr: 1.344 ± 0.34
1.222HisVal: 1.222 ± 0.475
0.244HisTrp: 0.244 ± 0.179
0.489HisTyr: 0.489 ± 0.231
0.0HisXaa: 0.0 ± 0.0
Ile
4.277IleAla: 4.277 ± 0.764
0.733IleCys: 0.733 ± 0.325
2.444IleAsp: 2.444 ± 0.545
3.177IleGlu: 3.177 ± 0.726
2.81IlePhe: 2.81 ± 0.514
3.055IleGly: 3.055 ± 0.88
1.466IleHis: 1.466 ± 0.38
2.81IleIle: 2.81 ± 0.652
3.299IleLys: 3.299 ± 0.644
5.499IleLeu: 5.499 ± 0.822
1.222IleMet: 1.222 ± 0.284
2.933IleAsn: 2.933 ± 0.505
3.543IlePro: 3.543 ± 0.872
2.322IleGln: 2.322 ± 0.48
2.444IleArg: 2.444 ± 0.557
4.643IleSer: 4.643 ± 0.749
4.521IleThr: 4.521 ± 0.768
3.421IleVal: 3.421 ± 0.667
0.489IleTrp: 0.489 ± 0.265
2.566IleTyr: 2.566 ± 0.618
0.0IleXaa: 0.0 ± 0.0
Lys
4.643LysAla: 4.643 ± 1.002
1.222LysCys: 1.222 ± 0.561
2.933LysAsp: 2.933 ± 0.738
4.154LysGlu: 4.154 ± 0.785
2.933LysPhe: 2.933 ± 0.858
2.566LysGly: 2.566 ± 0.761
0.855LysHis: 0.855 ± 0.355
4.032LysIle: 4.032 ± 0.78
4.765LysLys: 4.765 ± 0.887
5.254LysLeu: 5.254 ± 1.401
0.978LysMet: 0.978 ± 0.391
3.543LysAsn: 3.543 ± 0.916
1.955LysPro: 1.955 ± 0.41
3.177LysGln: 3.177 ± 0.558
4.399LysArg: 4.399 ± 1.629
4.277LysSer: 4.277 ± 0.816
3.177LysThr: 3.177 ± 0.66
3.299LysVal: 3.299 ± 0.636
0.611LysTrp: 0.611 ± 0.234
2.566LysTyr: 2.566 ± 0.64
0.0LysXaa: 0.0 ± 0.0
Leu
5.621LeuAla: 5.621 ± 0.825
1.466LeuCys: 1.466 ± 0.464
3.91LeuAsp: 3.91 ± 0.581
4.643LeuGlu: 4.643 ± 0.924
2.81LeuPhe: 2.81 ± 0.562
6.232LeuGly: 6.232 ± 1.03
2.566LeuHis: 2.566 ± 0.582
4.521LeuIle: 4.521 ± 0.663
9.286LeuLys: 9.286 ± 1.696
9.042LeuLeu: 9.042 ± 1.436
2.688LeuMet: 2.688 ± 0.645
4.888LeuAsn: 4.888 ± 0.862
5.499LeuPro: 5.499 ± 0.922
5.743LeuGln: 5.743 ± 1.137
4.154LeuArg: 4.154 ± 0.76
6.598LeuSer: 6.598 ± 1.187
5.132LeuThr: 5.132 ± 0.756
4.154LeuVal: 4.154 ± 0.681
1.833LeuTrp: 1.833 ± 0.419
3.421LeuTyr: 3.421 ± 0.837
0.0LeuXaa: 0.0 ± 0.0
Met
1.711MetAla: 1.711 ± 0.366
0.611MetCys: 0.611 ± 0.289
1.222MetAsp: 1.222 ± 0.32
0.978MetGlu: 0.978 ± 0.235
1.222MetPhe: 1.222 ± 0.297
1.344MetGly: 1.344 ± 0.287
0.978MetHis: 0.978 ± 0.39
0.855MetIle: 0.855 ± 0.326
0.978MetLys: 0.978 ± 0.432
1.955MetLeu: 1.955 ± 0.49
0.367MetMet: 0.367 ± 0.259
1.588MetAsn: 1.588 ± 0.331
2.199MetPro: 2.199 ± 0.45
0.855MetGln: 0.855 ± 0.266
1.222MetArg: 1.222 ± 0.433
1.588MetSer: 1.588 ± 0.34
1.1MetThr: 1.1 ± 0.328
1.222MetVal: 1.222 ± 0.311
0.0MetTrp: 0.0 ± 0.0
1.466MetTyr: 1.466 ± 0.306
0.0MetXaa: 0.0 ± 0.0
Asn
3.299AsnAla: 3.299 ± 0.586
0.733AsnCys: 0.733 ± 0.313
2.444AsnAsp: 2.444 ± 0.49
4.399AsnGlu: 4.399 ± 0.651
4.032AsnPhe: 4.032 ± 0.449
3.177AsnGly: 3.177 ± 0.742
1.1AsnHis: 1.1 ± 0.361
5.01AsnIle: 5.01 ± 0.73
2.688AsnLys: 2.688 ± 0.752
6.476AsnLeu: 6.476 ± 0.684
1.222AsnMet: 1.222 ± 0.428
3.91AsnAsn: 3.91 ± 0.882
4.032AsnPro: 4.032 ± 0.647
2.322AsnGln: 2.322 ± 0.574
2.688AsnArg: 2.688 ± 0.567
4.765AsnSer: 4.765 ± 0.587
2.688AsnThr: 2.688 ± 0.685
2.688AsnVal: 2.688 ± 0.473
0.978AsnTrp: 0.978 ± 0.394
3.177AsnTyr: 3.177 ± 0.774
0.0AsnXaa: 0.0 ± 0.0
Pro
3.543ProAla: 3.543 ± 0.613
0.855ProCys: 0.855 ± 0.33
2.566ProAsp: 2.566 ± 0.554
2.933ProGlu: 2.933 ± 0.518
3.055ProPhe: 3.055 ± 0.414
2.566ProGly: 2.566 ± 0.468
1.1ProHis: 1.1 ± 0.342
2.688ProIle: 2.688 ± 0.45
2.933ProLys: 2.933 ± 0.681
5.499ProLeu: 5.499 ± 0.839
2.322ProMet: 2.322 ± 0.365
3.177ProAsn: 3.177 ± 0.652
5.987ProPro: 5.987 ± 1.013
2.199ProGln: 2.199 ± 0.682
3.177ProArg: 3.177 ± 0.679
3.788ProSer: 3.788 ± 0.843
3.421ProThr: 3.421 ± 0.519
3.788ProVal: 3.788 ± 0.851
0.367ProTrp: 0.367 ± 0.25
2.199ProTyr: 2.199 ± 0.539
0.0ProXaa: 0.0 ± 0.0
Gln
3.788GlnAla: 3.788 ± 0.658
0.611GlnCys: 0.611 ± 0.175
1.222GlnAsp: 1.222 ± 0.332
2.688GlnGlu: 2.688 ± 0.532
1.222GlnPhe: 1.222 ± 0.327
2.688GlnGly: 2.688 ± 0.401
0.978GlnHis: 0.978 ± 0.355
2.322GlnIle: 2.322 ± 0.566
2.444GlnLys: 2.444 ± 0.588
4.765GlnLeu: 4.765 ± 1.037
0.733GlnMet: 0.733 ± 0.278
2.566GlnAsn: 2.566 ± 0.566
1.833GlnPro: 1.833 ± 0.465
1.955GlnGln: 1.955 ± 0.471
1.711GlnArg: 1.711 ± 0.578
3.91GlnSer: 3.91 ± 0.942
3.666GlnThr: 3.666 ± 0.723
2.444GlnVal: 2.444 ± 0.521
0.489GlnTrp: 0.489 ± 0.203
0.978GlnTyr: 0.978 ± 0.365
0.0GlnXaa: 0.0 ± 0.0
Arg
3.788ArgAla: 3.788 ± 0.883
1.1ArgCys: 1.1 ± 0.359
1.344ArgAsp: 1.344 ± 0.304
2.81ArgGlu: 2.81 ± 0.612
2.322ArgPhe: 2.322 ± 0.673
2.322ArgGly: 2.322 ± 0.613
0.611ArgHis: 0.611 ± 0.301
3.299ArgIle: 3.299 ± 0.581
3.788ArgLys: 3.788 ± 0.775
4.643ArgLeu: 4.643 ± 0.594
1.1ArgMet: 1.1 ± 0.376
4.154ArgAsn: 4.154 ± 0.77
2.199ArgPro: 2.199 ± 0.552
1.955ArgGln: 1.955 ± 0.485
4.888ArgArg: 4.888 ± 1.568
3.055ArgSer: 3.055 ± 0.748
2.81ArgThr: 2.81 ± 0.691
2.933ArgVal: 2.933 ± 0.909
0.855ArgTrp: 0.855 ± 0.26
1.833ArgTyr: 1.833 ± 0.557
0.0ArgXaa: 0.0 ± 0.0
Ser
3.91SerAla: 3.91 ± 0.606
1.222SerCys: 1.222 ± 0.617
3.177SerAsp: 3.177 ± 0.697
3.788SerGlu: 3.788 ± 0.664
4.765SerPhe: 4.765 ± 0.779
4.888SerGly: 4.888 ± 0.8
1.1SerHis: 1.1 ± 0.438
3.666SerIle: 3.666 ± 0.727
3.91SerLys: 3.91 ± 0.737
6.965SerLeu: 6.965 ± 0.996
1.222SerMet: 1.222 ± 0.333
4.765SerAsn: 4.765 ± 0.993
3.788SerPro: 3.788 ± 0.579
2.444SerGln: 2.444 ± 0.433
3.177SerArg: 3.177 ± 0.672
5.743SerSer: 5.743 ± 0.924
4.154SerThr: 4.154 ± 0.843
5.376SerVal: 5.376 ± 0.726
0.733SerTrp: 0.733 ± 0.318
3.299SerTyr: 3.299 ± 0.993
0.0SerXaa: 0.0 ± 0.0
Thr
3.421ThrAla: 3.421 ± 0.685
1.222ThrCys: 1.222 ± 0.405
2.688ThrAsp: 2.688 ± 0.449
3.421ThrGlu: 3.421 ± 0.428
2.688ThrPhe: 2.688 ± 0.431
2.81ThrGly: 2.81 ± 0.774
0.978ThrHis: 0.978 ± 0.333
3.299ThrIle: 3.299 ± 0.578
3.055ThrLys: 3.055 ± 0.794
7.331ThrLeu: 7.331 ± 0.79
1.344ThrMet: 1.344 ± 0.465
3.421ThrAsn: 3.421 ± 0.563
3.788ThrPro: 3.788 ± 0.751
2.199ThrGln: 2.199 ± 0.403
3.177ThrArg: 3.177 ± 0.535
4.643ThrSer: 4.643 ± 0.794
3.055ThrThr: 3.055 ± 0.576
3.788ThrVal: 3.788 ± 0.618
0.733ThrTrp: 0.733 ± 0.345
2.933ThrTyr: 2.933 ± 0.728
0.0ThrXaa: 0.0 ± 0.0
Val
2.566ValAla: 2.566 ± 0.492
0.855ValCys: 0.855 ± 0.22
2.933ValAsp: 2.933 ± 0.973
3.055ValGlu: 3.055 ± 0.623
2.566ValPhe: 2.566 ± 0.318
3.055ValGly: 3.055 ± 0.662
0.611ValHis: 0.611 ± 0.34
3.299ValIle: 3.299 ± 0.502
3.91ValLys: 3.91 ± 0.966
5.254ValLeu: 5.254 ± 0.556
1.1ValMet: 1.1 ± 0.32
3.788ValAsn: 3.788 ± 0.98
4.765ValPro: 4.765 ± 0.868
3.055ValGln: 3.055 ± 0.644
2.933ValArg: 2.933 ± 0.924
4.643ValSer: 4.643 ± 0.803
5.01ValThr: 5.01 ± 0.61
3.299ValVal: 3.299 ± 0.397
0.244ValTrp: 0.244 ± 0.137
3.055ValTyr: 3.055 ± 0.442
0.0ValXaa: 0.0 ± 0.0
Trp
0.855TrpAla: 0.855 ± 0.292
0.0TrpCys: 0.0 ± 0.0
0.611TrpAsp: 0.611 ± 0.319
0.611TrpGlu: 0.611 ± 0.27
0.122TrpPhe: 0.122 ± 0.115
0.978TrpGly: 0.978 ± 0.35
0.122TrpHis: 0.122 ± 0.115
0.244TrpIle: 0.244 ± 0.156
1.1TrpLys: 1.1 ± 0.558
0.611TrpLeu: 0.611 ± 0.217
0.733TrpMet: 0.733 ± 0.279
0.367TrpAsn: 0.367 ± 0.202
0.611TrpPro: 0.611 ± 0.258
1.222TrpGln: 1.222 ± 0.494
0.244TrpArg: 0.244 ± 0.147
0.733TrpSer: 0.733 ± 0.372
1.1TrpThr: 1.1 ± 0.404
0.367TrpVal: 0.367 ± 0.203
0.122TrpTrp: 0.122 ± 0.115
0.244TrpTyr: 0.244 ± 0.171
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.711TyrAla: 1.711 ± 0.616
0.855TyrCys: 0.855 ± 0.29
2.444TyrAsp: 2.444 ± 0.754
2.322TyrGlu: 2.322 ± 0.556
1.588TyrPhe: 1.588 ± 0.458
1.833TyrGly: 1.833 ± 0.453
1.711TyrHis: 1.711 ± 0.543
1.833TyrIle: 1.833 ± 0.479
2.322TyrLys: 2.322 ± 0.848
3.177TyrLeu: 3.177 ± 0.97
1.466TyrMet: 1.466 ± 0.331
2.688TyrAsn: 2.688 ± 0.656
2.077TyrPro: 2.077 ± 0.367
2.199TyrGln: 2.199 ± 0.524
1.466TyrArg: 1.466 ± 0.401
3.421TyrSer: 3.421 ± 0.808
2.566TyrThr: 2.566 ± 0.432
2.688TyrVal: 2.688 ± 0.561
0.244TyrTrp: 0.244 ± 0.156
1.711TyrTyr: 1.711 ± 0.461
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 25 proteins (8185 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski