Amino acid dipepetide frequency for Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) (Pirella staleyi)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.128AlaAla: 14.128 ± 0.146
1.041AlaCys: 1.041 ± 0.027
5.793AlaAsp: 5.793 ± 0.067
7.166AlaGlu: 7.166 ± 0.08
2.896AlaPhe: 2.896 ± 0.042
8.102AlaGly: 8.102 ± 0.105
1.784AlaHis: 1.784 ± 0.031
6.13AlaIle: 6.13 ± 0.068
4.662AlaLys: 4.662 ± 0.07
9.087AlaLeu: 9.087 ± 0.088
2.779AlaMet: 2.779 ± 0.045
2.66AlaAsn: 2.66 ± 0.057
5.51AlaPro: 5.51 ± 0.102
3.695AlaGln: 3.695 ± 0.056
6.452AlaArg: 6.452 ± 0.071
7.421AlaSer: 7.421 ± 0.071
6.761AlaThr: 6.761 ± 0.082
6.838AlaVal: 6.838 ± 0.068
1.369AlaTrp: 1.369 ± 0.03
2.012AlaTyr: 2.012 ± 0.039
0.0AlaXaa: 0.0 ± 0.0
Cys
0.788CysAla: 0.788 ± 0.02
0.235CysCys: 0.235 ± 0.017
0.711CysAsp: 0.711 ± 0.021
0.656CysGlu: 0.656 ± 0.021
0.407CysPhe: 0.407 ± 0.015
1.028CysGly: 1.028 ± 0.026
0.392CysHis: 0.392 ± 0.016
0.41CysIle: 0.41 ± 0.016
0.382CysLys: 0.382 ± 0.018
0.974CysLeu: 0.974 ± 0.026
0.178CysMet: 0.178 ± 0.01
0.29CysAsn: 0.29 ± 0.013
0.551CysPro: 0.551 ± 0.02
0.403CysGln: 0.403 ± 0.017
0.734CysArg: 0.734 ± 0.021
0.628CysSer: 0.628 ± 0.018
0.587CysThr: 0.587 ± 0.021
0.671CysVal: 0.671 ± 0.02
0.184CysTrp: 0.184 ± 0.011
0.344CysTyr: 0.344 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
5.444AspAla: 5.444 ± 0.052
0.541AspCys: 0.541 ± 0.02
3.379AspAsp: 3.379 ± 0.057
3.832AspGlu: 3.832 ± 0.055
2.181AspPhe: 2.181 ± 0.036
4.363AspGly: 4.363 ± 0.079
1.24AspHis: 1.24 ± 0.029
2.303AspIle: 2.303 ± 0.049
1.985AspLys: 1.985 ± 0.037
5.676AspLeu: 5.676 ± 0.054
0.906AspMet: 0.906 ± 0.02
1.486AspAsn: 1.486 ± 0.035
3.454AspPro: 3.454 ± 0.053
2.168AspGln: 2.168 ± 0.037
3.73AspArg: 3.73 ± 0.056
3.07AspSer: 3.07 ± 0.044
2.483AspThr: 2.483 ± 0.053
3.746AspVal: 3.746 ± 0.056
0.902AspTrp: 0.902 ± 0.023
1.522AspTyr: 1.522 ± 0.032
0.0AspXaa: 0.0 ± 0.0
Glu
6.416GluAla: 6.416 ± 0.077
0.467GluCys: 0.467 ± 0.015
2.3GluAsp: 2.3 ± 0.037
3.729GluGlu: 3.729 ± 0.069
2.219GluPhe: 2.219 ± 0.041
3.978GluGly: 3.978 ± 0.06
1.365GluHis: 1.365 ± 0.031
3.446GluIle: 3.446 ± 0.046
3.239GluLys: 3.239 ± 0.056
7.111GluLeu: 7.111 ± 0.073
1.565GluMet: 1.565 ± 0.028
1.926GluAsn: 1.926 ± 0.037
3.033GluPro: 3.033 ± 0.045
3.145GluGln: 3.145 ± 0.045
4.199GluArg: 4.199 ± 0.055
3.786GluSer: 3.786 ± 0.05
3.431GluThr: 3.431 ± 0.047
4.733GluVal: 4.733 ± 0.051
0.759GluTrp: 0.759 ± 0.023
1.292GluTyr: 1.292 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
3.633PheAla: 3.633 ± 0.052
0.469PheCys: 0.469 ± 0.013
2.394PheAsp: 2.394 ± 0.036
2.213PheGlu: 2.213 ± 0.043
1.306PhePhe: 1.306 ± 0.032
2.974PheGly: 2.974 ± 0.051
0.739PheHis: 0.739 ± 0.024
1.317PheIle: 1.317 ± 0.028
0.961PheLys: 0.961 ± 0.025
3.291PheLeu: 3.291 ± 0.047
0.591PheMet: 0.591 ± 0.018
0.962PheAsn: 0.962 ± 0.028
1.732PhePro: 1.732 ± 0.032
1.261PheGln: 1.261 ± 0.026
2.192PheArg: 2.192 ± 0.034
2.364PheSer: 2.364 ± 0.042
2.107PheThr: 2.107 ± 0.043
2.568PheVal: 2.568 ± 0.042
0.517PheTrp: 0.517 ± 0.016
0.899PheTyr: 0.899 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
6.337GlyAla: 6.337 ± 0.108
1.052GlyCys: 1.052 ± 0.026
4.36GlyAsp: 4.36 ± 0.068
4.768GlyGlu: 4.768 ± 0.06
2.675GlyPhe: 2.675 ± 0.046
6.686GlyGly: 6.686 ± 0.142
1.489GlyHis: 1.489 ± 0.034
3.952GlyIle: 3.952 ± 0.055
3.929GlyLys: 3.929 ± 0.061
6.794GlyLeu: 6.794 ± 0.071
1.9GlyMet: 1.9 ± 0.036
2.743GlyAsn: 2.743 ± 0.095
3.216GlyPro: 3.216 ± 0.048
2.745GlyGln: 2.745 ± 0.044
4.462GlyArg: 4.462 ± 0.052
5.226GlySer: 5.226 ± 0.073
4.608GlyThr: 4.608 ± 0.12
5.205GlyVal: 5.205 ± 0.071
1.143GlyTrp: 1.143 ± 0.023
2.132GlyTyr: 2.132 ± 0.035
0.0GlyXaa: 0.0 ± 0.0
His
1.905HisAla: 1.905 ± 0.037
0.306HisCys: 0.306 ± 0.013
1.206HisAsp: 1.206 ± 0.031
1.257HisGlu: 1.257 ± 0.031
0.896HisPhe: 0.896 ± 0.023
1.671HisGly: 1.671 ± 0.034
0.653HisHis: 0.653 ± 0.022
0.742HisIle: 0.742 ± 0.021
0.579HisLys: 0.579 ± 0.018
2.29HisLeu: 2.29 ± 0.039
0.33HisMet: 0.33 ± 0.014
0.573HisAsn: 0.573 ± 0.02
1.425HisPro: 1.425 ± 0.033
0.863HisGln: 0.863 ± 0.024
1.46HisArg: 1.46 ± 0.032
1.125HisSer: 1.125 ± 0.028
1.015HisThr: 1.015 ± 0.022
1.334HisVal: 1.334 ± 0.033
0.378HisTrp: 0.378 ± 0.016
0.614HisTyr: 0.614 ± 0.02
0.0HisXaa: 0.0 ± 0.0
Ile
6.248IleAla: 6.248 ± 0.071
0.601IleCys: 0.601 ± 0.018
3.866IleAsp: 3.866 ± 0.053
3.84IleGlu: 3.84 ± 0.05
1.521IlePhe: 1.521 ± 0.034
3.884IleGly: 3.884 ± 0.057
0.944IleHis: 0.944 ± 0.024
1.905IleIle: 1.905 ± 0.038
1.559IleLys: 1.559 ± 0.035
4.136IleLeu: 4.136 ± 0.061
0.648IleMet: 0.648 ± 0.019
1.446IleAsn: 1.446 ± 0.051
2.621IlePro: 2.621 ± 0.043
1.448IleGln: 1.448 ± 0.028
3.045IleArg: 3.045 ± 0.039
3.06IleSer: 3.06 ± 0.047
3.058IleThr: 3.058 ± 0.056
4.019IleVal: 4.019 ± 0.049
0.561IleTrp: 0.561 ± 0.021
1.194IleTyr: 1.194 ± 0.028
0.0IleXaa: 0.0 ± 0.0
Lys
3.269LysAla: 3.269 ± 0.054
0.361LysCys: 0.361 ± 0.014
1.578LysAsp: 1.578 ± 0.038
2.287LysGlu: 2.287 ± 0.045
1.519LysPhe: 1.519 ± 0.034
2.226LysGly: 2.226 ± 0.043
0.883LysHis: 0.883 ± 0.023
2.179LysIle: 2.179 ± 0.044
2.061LysLys: 2.061 ± 0.053
5.132LysLeu: 5.132 ± 0.07
1.084LysMet: 1.084 ± 0.028
1.249LysAsn: 1.249 ± 0.028
2.634LysPro: 2.634 ± 0.049
1.866LysGln: 1.866 ± 0.036
2.44LysArg: 2.44 ± 0.04
2.764LysSer: 2.764 ± 0.043
2.331LysThr: 2.331 ± 0.044
2.726LysVal: 2.726 ± 0.047
0.537LysTrp: 0.537 ± 0.016
1.001LysTyr: 1.001 ± 0.029
0.0LysXaa: 0.0 ± 0.0
Leu
13.563LeuAla: 13.563 ± 0.137
1.033LeuCys: 1.033 ± 0.024
5.69LeuAsp: 5.69 ± 0.064
6.573LeuGlu: 6.573 ± 0.08
3.159LeuPhe: 3.159 ± 0.051
7.625LeuGly: 7.625 ± 0.09
1.927LeuHis: 1.927 ± 0.041
4.25LeuIle: 4.25 ± 0.058
3.808LeuLys: 3.808 ± 0.063
11.589LeuLeu: 11.589 ± 0.121
1.973LeuMet: 1.973 ± 0.04
2.245LeuAsn: 2.245 ± 0.045
6.091LeuPro: 6.091 ± 0.074
3.599LeuGln: 3.599 ± 0.052
6.585LeuArg: 6.585 ± 0.085
6.719LeuSer: 6.719 ± 0.071
5.894LeuThr: 5.894 ± 0.072
8.119LeuVal: 8.119 ± 0.086
1.259LeuTrp: 1.259 ± 0.03
2.072LeuTyr: 2.072 ± 0.034
0.0LeuXaa: 0.0 ± 0.0
Met
2.169MetAla: 2.169 ± 0.037
0.19MetCys: 0.19 ± 0.01
0.756MetAsp: 0.756 ± 0.019
0.984MetGlu: 0.984 ± 0.026
0.753MetPhe: 0.753 ± 0.021
1.391MetGly: 1.391 ± 0.034
0.527MetHis: 0.527 ± 0.018
1.234MetIle: 1.234 ± 0.029
1.014MetLys: 1.014 ± 0.027
2.679MetLeu: 2.679 ± 0.043
0.595MetMet: 0.595 ± 0.023
0.805MetAsn: 0.805 ± 0.02
1.455MetPro: 1.455 ± 0.034
1.024MetGln: 1.024 ± 0.025
1.377MetArg: 1.377 ± 0.028
1.557MetSer: 1.557 ± 0.03
1.347MetThr: 1.347 ± 0.029
1.568MetVal: 1.568 ± 0.03
0.233MetTrp: 0.233 ± 0.011
0.398MetTyr: 0.398 ± 0.016
0.0MetXaa: 0.0 ± 0.0
Asn
2.424AsnAla: 2.424 ± 0.058
0.351AsnCys: 0.351 ± 0.014
1.61AsnAsp: 1.61 ± 0.058
1.447AsnGlu: 1.447 ± 0.031
1.255AsnPhe: 1.255 ± 0.031
2.197AsnGly: 2.197 ± 0.075
0.615AsnHis: 0.615 ± 0.02
1.364AsnIle: 1.364 ± 0.038
0.863AsnLys: 0.863 ± 0.025
3.069AsnLeu: 3.069 ± 0.05
0.54AsnMet: 0.54 ± 0.019
1.007AsnAsn: 1.007 ± 0.041
1.948AsnPro: 1.948 ± 0.037
1.04AsnGln: 1.04 ± 0.025
1.834AsnArg: 1.834 ± 0.037
1.819AsnSer: 1.819 ± 0.046
1.483AsnThr: 1.483 ± 0.043
2.101AsnVal: 2.101 ± 0.05
0.523AsnTrp: 0.523 ± 0.018
0.92AsnTyr: 0.92 ± 0.022
0.0AsnXaa: 0.0 ± 0.0
Pro
6.991ProAla: 6.991 ± 0.106
0.405ProCys: 0.405 ± 0.017
2.788ProAsp: 2.788 ± 0.043
3.638ProGlu: 3.638 ± 0.051
1.698ProPhe: 1.698 ± 0.034
4.115ProGly: 4.115 ± 0.06
1.133ProHis: 1.133 ± 0.03
2.695ProIle: 2.695 ± 0.04
2.164ProLys: 2.164 ± 0.043
5.452ProLeu: 5.452 ± 0.061
1.291ProMet: 1.291 ± 0.033
1.437ProAsn: 1.437 ± 0.03
3.61ProPro: 3.61 ± 0.078
2.372ProGln: 2.372 ± 0.045
2.982ProArg: 2.982 ± 0.047
3.946ProSer: 3.946 ± 0.049
3.494ProThr: 3.494 ± 0.048
3.728ProVal: 3.728 ± 0.054
0.73ProTrp: 0.73 ± 0.023
1.165ProTyr: 1.165 ± 0.029
0.0ProXaa: 0.0 ± 0.0
Gln
3.86GlnAla: 3.86 ± 0.058
0.336GlnCys: 0.336 ± 0.014
1.293GlnAsp: 1.293 ± 0.026
1.901GlnGlu: 1.901 ± 0.034
1.448GlnPhe: 1.448 ± 0.025
2.513GlnGly: 2.513 ± 0.041
0.842GlnHis: 0.842 ± 0.025
2.066GlnIle: 2.066 ± 0.034
1.631GlnLys: 1.631 ± 0.034
5.27GlnLeu: 5.27 ± 0.063
0.984GlnMet: 0.984 ± 0.025
1.099GlnAsn: 1.099 ± 0.023
2.573GlnPro: 2.573 ± 0.045
2.372GlnGln: 2.372 ± 0.055
2.553GlnArg: 2.553 ± 0.049
2.509GlnSer: 2.509 ± 0.041
2.07GlnThr: 2.07 ± 0.035
2.854GlnVal: 2.854 ± 0.045
0.585GlnTrp: 0.585 ± 0.019
0.847GlnTyr: 0.847 ± 0.023
0.0GlnXaa: 0.0 ± 0.0
Arg
5.642ArgAla: 5.642 ± 0.079
0.678ArgCys: 0.678 ± 0.02
3.636ArgAsp: 3.636 ± 0.048
4.474ArgGlu: 4.474 ± 0.062
2.417ArgPhe: 2.417 ± 0.035
4.392ArgGly: 4.392 ± 0.053
1.294ArgHis: 1.294 ± 0.029
3.199ArgIle: 3.199 ± 0.043
2.497ArgLys: 2.497 ± 0.047
6.722ArgLeu: 6.722 ± 0.07
1.665ArgMet: 1.665 ± 0.035
1.678ArgAsn: 1.678 ± 0.033
3.034ArgPro: 3.034 ± 0.045
2.64ArgGln: 2.64 ± 0.048
4.655ArgArg: 4.655 ± 0.069
4.136ArgSer: 4.136 ± 0.051
3.21ArgThr: 3.21 ± 0.041
4.411ArgVal: 4.411 ± 0.047
1.129ArgTrp: 1.129 ± 0.024
1.739ArgTyr: 1.739 ± 0.031
0.0ArgXaa: 0.0 ± 0.0
Ser
6.326SerAla: 6.326 ± 0.071
0.659SerCys: 0.659 ± 0.02
3.816SerAsp: 3.816 ± 0.045
3.787SerGlu: 3.787 ± 0.056
2.234SerPhe: 2.234 ± 0.043
5.752SerGly: 5.752 ± 0.103
1.336SerHis: 1.336 ± 0.029
3.404SerIle: 3.404 ± 0.051
2.428SerLys: 2.428 ± 0.042
7.1SerLeu: 7.1 ± 0.069
1.5SerMet: 1.5 ± 0.032
1.811SerAsn: 1.811 ± 0.044
3.866SerPro: 3.866 ± 0.052
2.721SerGln: 2.721 ± 0.048
4.233SerArg: 4.233 ± 0.059
5.312SerSer: 5.312 ± 0.086
4.011SerThr: 4.011 ± 0.06
4.083SerVal: 4.083 ± 0.052
0.91SerTrp: 0.91 ± 0.025
1.52SerTyr: 1.52 ± 0.03
0.0SerXaa: 0.0 ± 0.0
Thr
5.974ThrAla: 5.974 ± 0.081
0.535ThrCys: 0.535 ± 0.02
2.918ThrAsp: 2.918 ± 0.045
2.922ThrGlu: 2.922 ± 0.039
2.081ThrPhe: 2.081 ± 0.046
4.777ThrGly: 4.777 ± 0.098
1.123ThrHis: 1.123 ± 0.027
3.482ThrIle: 3.482 ± 0.064
2.186ThrLys: 2.186 ± 0.042
6.227ThrLeu: 6.227 ± 0.089
1.154ThrMet: 1.154 ± 0.026
1.666ThrAsn: 1.666 ± 0.042
3.733ThrPro: 3.733 ± 0.056
1.887ThrGln: 1.887 ± 0.033
3.051ThrArg: 3.051 ± 0.045
4.443ThrSer: 4.443 ± 0.073
3.849ThrThr: 3.849 ± 0.075
3.679ThrVal: 3.679 ± 0.063
0.835ThrTrp: 0.835 ± 0.021
1.417ThrTyr: 1.417 ± 0.036
0.0ThrXaa: 0.0 ± 0.0
Val
8.085ValAla: 8.085 ± 0.072
0.766ValCys: 0.766 ± 0.025
4.166ValAsp: 4.166 ± 0.052
4.53ValGlu: 4.53 ± 0.058
2.223ValPhe: 2.223 ± 0.032
4.954ValGly: 4.954 ± 0.058
1.38ValHis: 1.38 ± 0.033
3.81ValIle: 3.81 ± 0.051
2.719ValLys: 2.719 ± 0.053
6.95ValLeu: 6.95 ± 0.068
1.603ValMet: 1.603 ± 0.032
2.03ValAsn: 2.03 ± 0.048
3.511ValPro: 3.511 ± 0.047
2.419ValGln: 2.419 ± 0.039
4.465ValArg: 4.465 ± 0.051
4.448ValSer: 4.448 ± 0.062
4.27ValThr: 4.27 ± 0.066
5.991ValVal: 5.991 ± 0.061
0.937ValTrp: 0.937 ± 0.024
1.535ValTyr: 1.535 ± 0.031
0.0ValXaa: 0.0 ± 0.0
Trp
0.946TrpAla: 0.946 ± 0.022
0.181TrpCys: 0.181 ± 0.01
0.671TrpAsp: 0.671 ± 0.018
0.674TrpGlu: 0.674 ± 0.022
0.509TrpPhe: 0.509 ± 0.016
0.913TrpGly: 0.913 ± 0.026
0.383TrpHis: 0.383 ± 0.015
0.835TrpIle: 0.835 ± 0.023
0.716TrpLys: 0.716 ± 0.023
1.693TrpLeu: 1.693 ± 0.031
0.415TrpMet: 0.415 ± 0.016
0.622TrpAsn: 0.622 ± 0.02
0.689TrpPro: 0.689 ± 0.019
0.835TrpGln: 0.835 ± 0.025
0.929TrpArg: 0.929 ± 0.027
0.994TrpSer: 0.994 ± 0.027
0.73TrpThr: 0.73 ± 0.018
0.791TrpVal: 0.791 ± 0.021
0.277TrpTrp: 0.277 ± 0.014
0.34TrpTyr: 0.34 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.139TyrAla: 2.139 ± 0.041
0.346TyrCys: 0.346 ± 0.014
1.479TyrAsp: 1.479 ± 0.029
1.46TyrGlu: 1.46 ± 0.031
1.092TyrPhe: 1.092 ± 0.026
1.884TyrGly: 1.884 ± 0.037
0.572TyrHis: 0.572 ± 0.019
0.88TyrIle: 0.88 ± 0.025
0.746TyrLys: 0.746 ± 0.021
2.531TyrLeu: 2.531 ± 0.037
0.358TyrMet: 0.358 ± 0.014
0.676TyrAsn: 0.676 ± 0.024
1.146TyrPro: 1.146 ± 0.026
1.101TyrGln: 1.101 ± 0.028
1.867TyrArg: 1.867 ± 0.037
1.482TyrSer: 1.482 ± 0.033
1.202TyrThr: 1.202 ± 0.033
1.628TyrVal: 1.628 ± 0.031
0.376TyrTrp: 0.376 ± 0.014
0.774TyrTyr: 0.774 ± 0.024
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4711 proteins (1765092 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski