Amino acid dipepetide frequency for Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.833AlaAla: 16.833 ± 0.197	1.292AlaCys: 1.292 ± 0.039	6.889AlaAsp: 6.889 ± 0.102	6.331AlaGlu: 6.331 ± 0.099	3.703AlaPhe: 3.703 ± 0.072	9.681AlaGly: 9.681 ± 0.13	3.105AlaHis: 3.105 ± 0.076	5.49AlaIle: 5.49 ± 0.063	3.368AlaLys: 3.368 ± 0.08	15.927AlaLeu: 15.927 ± 0.17	3.315AlaMet: 3.315 ± 0.064	3.072AlaAsn: 3.072 ± 0.057	6.104AlaPro: 6.104 ± 0.103	6.829AlaGln: 6.829 ± 0.106	8.798AlaArg: 8.798 ± 0.108	6.859AlaSer: 6.859 ± 0.097	6.418AlaThr: 6.418 ± 0.099	8.233AlaVal: 8.233 ± 0.102	1.862AlaTrp: 1.862 ± 0.05	2.882AlaTyr: 2.882 ± 0.094	0.0AlaXaa: 0.0 ± 0.0
Cys	1.238CysAla: 1.238 ± 0.038	0.119CysCys: 0.119 ± 0.012	0.575CysAsp: 0.575 ± 0.027	0.473CysGlu: 0.473 ± 0.021	0.28CysPhe: 0.28 ± 0.016	0.882CysGly: 0.882 ± 0.028	0.272CysHis: 0.272 ± 0.017	0.401CysIle: 0.401 ± 0.02	0.231CysLys: 0.231 ± 0.015	0.907CysLeu: 0.907 ± 0.033	0.202CysMet: 0.202 ± 0.014	0.258CysAsn: 0.258 ± 0.015	0.401CysPro: 0.401 ± 0.02	0.269CysGln: 0.269 ± 0.018	0.591CysArg: 0.591 ± 0.028	0.508CysSer: 0.508 ± 0.024	0.484CysThr: 0.484 ± 0.023	0.811CysVal: 0.811 ± 0.042	0.163CysTrp: 0.163 ± 0.012	0.241CysTyr: 0.241 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	8.431AspAla: 8.431 ± 0.121	0.468AspCys: 0.468 ± 0.025	3.131AspAsp: 3.131 ± 0.065	2.658AspGlu: 2.658 ± 0.048	1.85AspPhe: 1.85 ± 0.046	5.405AspGly: 5.405 ± 0.088	1.291AspHis: 1.291 ± 0.038	2.425AspIle: 2.425 ± 0.052	1.576AspLys: 1.576 ± 0.044	5.603AspLeu: 5.603 ± 0.079	1.137AspMet: 1.137 ± 0.04	1.535AspAsn: 1.535 ± 0.043	3.546AspPro: 3.546 ± 0.066	1.774AspGln: 1.774 ± 0.044	3.491AspArg: 3.491 ± 0.08	2.723AspSer: 2.723 ± 0.055	3.036AspThr: 3.036 ± 0.06	4.005AspVal: 4.005 ± 0.067	1.002AspTrp: 1.002 ± 0.033	1.8AspTyr: 1.8 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	5.963GluAla: 5.963 ± 0.096	0.396GluCys: 0.396 ± 0.025	2.324GluAsp: 2.324 ± 0.049	2.157GluGlu: 2.157 ± 0.062	1.472GluPhe: 1.472 ± 0.035	3.034GluGly: 3.034 ± 0.056	1.606GluHis: 1.606 ± 0.045	2.352GluIle: 2.352 ± 0.066	1.431GluLys: 1.431 ± 0.044	5.687GluLeu: 5.687 ± 0.116	1.005GluMet: 1.005 ± 0.03	1.197GluAsn: 1.197 ± 0.035	2.115GluPro: 2.115 ± 0.042	2.894GluGln: 2.894 ± 0.063	4.929GluArg: 4.929 ± 0.091	2.285GluSer: 2.285 ± 0.047	2.55GluThr: 2.55 ± 0.052	3.57GluVal: 3.57 ± 0.068	0.601GluTrp: 0.601 ± 0.026	1.053GluTyr: 1.053 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.165PheAla: 4.165 ± 0.057	0.334PheCys: 0.334 ± 0.018	2.447PheAsp: 2.447 ± 0.05	1.675PheGlu: 1.675 ± 0.048	1.201PhePhe: 1.201 ± 0.039	3.093PheGly: 3.093 ± 0.071	0.773PheHis: 0.773 ± 0.027	1.184PheIle: 1.184 ± 0.036	0.883PheLys: 0.883 ± 0.032	2.88PheLeu: 2.88 ± 0.055	0.593PheMet: 0.593 ± 0.025	1.057PheAsn: 1.057 ± 0.034	1.379PhePro: 1.379 ± 0.039	1.065PheGln: 1.065 ± 0.028	1.914PheArg: 1.914 ± 0.044	1.914PheSer: 1.914 ± 0.049	1.563PheThr: 1.563 ± 0.053	2.593PheVal: 2.593 ± 0.051	0.488PheTrp: 0.488 ± 0.022	0.82PheTyr: 0.82 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	8.466GlyAla: 8.466 ± 0.116	0.858GlyCys: 0.858 ± 0.026	4.374GlyAsp: 4.374 ± 0.067	4.298GlyGlu: 4.298 ± 0.074	3.091GlyPhe: 3.091 ± 0.059	6.723GlyGly: 6.723 ± 0.151	2.112GlyHis: 2.112 ± 0.044	3.863GlyIle: 3.863 ± 0.072	3.043GlyLys: 3.043 ± 0.067	8.211GlyLeu: 8.211 ± 0.105	2.129GlyMet: 2.129 ± 0.057	2.472GlyAsn: 2.472 ± 0.073	2.758GlyPro: 2.758 ± 0.059	3.413GlyGln: 3.413 ± 0.078	5.43GlyArg: 5.43 ± 0.07	4.807GlySer: 4.807 ± 0.1	4.334GlyThr: 4.334 ± 0.106	6.174GlyVal: 6.174 ± 0.08	1.451GlyTrp: 1.451 ± 0.038	2.397GlyTyr: 2.397 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	3.623HisAla: 3.623 ± 0.087	0.283HisCys: 0.283 ± 0.016	1.645HisAsp: 1.645 ± 0.044	1.106HisGlu: 1.106 ± 0.036	0.875HisPhe: 0.875 ± 0.029	2.474HisGly: 2.474 ± 0.049	0.754HisHis: 0.754 ± 0.036	0.916HisIle: 0.916 ± 0.032	0.519HisLys: 0.519 ± 0.025	2.587HisLeu: 2.587 ± 0.062	0.485HisMet: 0.485 ± 0.019	0.627HisAsn: 0.627 ± 0.023	1.568HisPro: 1.568 ± 0.045	0.821HisGln: 0.821 ± 0.037	1.7HisArg: 1.7 ± 0.045	1.342HisSer: 1.342 ± 0.036	1.17HisThr: 1.17 ± 0.035	1.64HisVal: 1.64 ± 0.045	0.527HisTrp: 0.527 ± 0.029	0.779HisTyr: 0.779 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.651IleAla: 6.651 ± 0.083	0.429IleCys: 0.429 ± 0.022	3.394IleAsp: 3.394 ± 0.061	2.932IleGlu: 2.932 ± 0.069	1.111IlePhe: 1.111 ± 0.034	4.543IleGly: 4.543 ± 0.08	0.841IleHis: 0.841 ± 0.025	1.299IleIle: 1.299 ± 0.042	1.324IleLys: 1.324 ± 0.039	3.323IleLeu: 3.323 ± 0.062	0.566IleMet: 0.566 ± 0.025	1.373IleAsn: 1.373 ± 0.042	1.99IlePro: 1.99 ± 0.039	1.297IleGln: 1.297 ± 0.035	2.516IleArg: 2.516 ± 0.054	2.276IleSer: 2.276 ± 0.046	2.202IleThr: 2.202 ± 0.048	3.431IleVal: 3.431 ± 0.068	0.485IleTrp: 0.485 ± 0.022	0.931IleTyr: 0.931 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	3.116LysAla: 3.116 ± 0.074	0.173LysCys: 0.173 ± 0.014	1.46LysAsp: 1.46 ± 0.05	1.172LysGlu: 1.172 ± 0.043	0.765LysPhe: 0.765 ± 0.027	1.906LysGly: 1.906 ± 0.045	0.693LysHis: 0.693 ± 0.027	1.355LysIle: 1.355 ± 0.04	1.069LysLys: 1.069 ± 0.051	3.028LysLeu: 3.028 ± 0.053	0.59LysMet: 0.59 ± 0.027	0.755LysAsn: 0.755 ± 0.029	1.772LysPro: 1.772 ± 0.046	1.413LysGln: 1.413 ± 0.043	2.164LysArg: 2.164 ± 0.048	1.544LysSer: 1.544 ± 0.046	1.601LysThr: 1.601 ± 0.05	2.04LysVal: 2.04 ± 0.053	0.266LysTrp: 0.266 ± 0.015	0.71LysTyr: 0.71 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	14.409LeuAla: 14.409 ± 0.146	1.2LeuCys: 1.2 ± 0.04	6.78LeuAsp: 6.78 ± 0.099	5.175LeuGlu: 5.175 ± 0.099	3.386LeuPhe: 3.386 ± 0.065	8.475LeuGly: 8.475 ± 0.108	2.937LeuHis: 2.937 ± 0.069	4.475LeuIle: 4.475 ± 0.064	2.838LeuLys: 2.838 ± 0.056	12.513LeuLeu: 12.513 ± 0.172	2.049LeuMet: 2.049 ± 0.048	2.786LeuAsn: 2.786 ± 0.063	6.842LeuPro: 6.842 ± 0.122	5.105LeuGln: 5.105 ± 0.075	9.113LeuArg: 9.113 ± 0.118	6.84LeuSer: 6.84 ± 0.118	5.304LeuThr: 5.304 ± 0.085	7.02LeuVal: 7.02 ± 0.086	1.385LeuTrp: 1.385 ± 0.049	2.471LeuTyr: 2.471 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.594MetAla: 2.594 ± 0.055	0.164MetCys: 0.164 ± 0.012	0.997MetAsp: 0.997 ± 0.036	0.856MetGlu: 0.856 ± 0.028	0.638MetPhe: 0.638 ± 0.02	1.394MetGly: 1.394 ± 0.044	0.573MetHis: 0.573 ± 0.024	0.865MetIle: 0.865 ± 0.027	0.72MetLys: 0.72 ± 0.029	2.598MetLeu: 2.598 ± 0.053	0.455MetMet: 0.455 ± 0.022	0.706MetAsn: 0.706 ± 0.024	1.49MetPro: 1.49 ± 0.048	1.113MetGln: 1.113 ± 0.033	1.802MetArg: 1.802 ± 0.038	1.542MetSer: 1.542 ± 0.045	1.329MetThr: 1.329 ± 0.033	1.495MetVal: 1.495 ± 0.044	0.185MetTrp: 0.185 ± 0.013	0.393MetTyr: 0.393 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.749AsnAla: 3.749 ± 0.087	0.201AsnCys: 0.201 ± 0.014	1.564AsnAsp: 1.564 ± 0.04	1.153AsnGlu: 1.153 ± 0.034	0.923AsnPhe: 0.923 ± 0.032	2.545AsnGly: 2.545 ± 0.073	0.539AsnHis: 0.539 ± 0.02	1.211AsnIle: 1.211 ± 0.037	0.73AsnLys: 0.73 ± 0.03	2.718AsnLeu: 2.718 ± 0.073	0.481AsnMet: 0.481 ± 0.023	0.827AsnAsn: 0.827 ± 0.036	1.788AsnPro: 1.788 ± 0.044	1.026AsnGln: 1.026 ± 0.035	1.813AsnArg: 1.813 ± 0.039	1.388AsnSer: 1.388 ± 0.046	1.584AsnThr: 1.584 ± 0.048	1.962AsnVal: 1.962 ± 0.047	0.412AsnTrp: 0.412 ± 0.023	0.765AsnTyr: 0.765 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	6.517ProAla: 6.517 ± 0.091	0.401ProCys: 0.401 ± 0.019	3.245ProAsp: 3.245 ± 0.079	2.827ProGlu: 2.827 ± 0.055	1.618ProPhe: 1.618 ± 0.045	4.31ProGly: 4.31 ± 0.084	1.328ProHis: 1.328 ± 0.04	2.042ProIle: 2.042 ± 0.052	1.323ProLys: 1.323 ± 0.04	5.935ProLeu: 5.935 ± 0.108	1.241ProMet: 1.241 ± 0.038	1.407ProAsn: 1.407 ± 0.037	3.076ProPro: 3.076 ± 0.08	2.511ProGln: 2.511 ± 0.048	3.282ProArg: 3.282 ± 0.059	3.004ProSer: 3.004 ± 0.056	2.717ProThr: 2.717 ± 0.052	3.807ProVal: 3.807 ± 0.069	0.797ProTrp: 0.797 ± 0.033	1.256ProTyr: 1.256 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	6.415GlnAla: 6.415 ± 0.103	0.329GlnCys: 0.329 ± 0.017	1.877GlnAsp: 1.877 ± 0.049	1.669GlnGlu: 1.669 ± 0.045	1.244GlnPhe: 1.244 ± 0.033	2.965GlnGly: 2.965 ± 0.058	1.28GlnHis: 1.28 ± 0.04	1.878GlnIle: 1.878 ± 0.039	0.944GlnLys: 0.944 ± 0.032	5.015GlnLeu: 5.015 ± 0.074	0.965GlnMet: 0.965 ± 0.033	1.008GlnAsn: 1.008 ± 0.048	2.396GlnPro: 2.396 ± 0.054	2.669GlnGln: 2.669 ± 0.065	4.43GlnArg: 4.43 ± 0.071	2.177GlnSer: 2.177 ± 0.051	2.229GlnThr: 2.229 ± 0.052	3.621GlnVal: 3.621 ± 0.072	0.775GlnTrp: 0.775 ± 0.025	0.833GlnTyr: 0.833 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	7.88ArgAla: 7.88 ± 0.103	0.642ArgCys: 0.642 ± 0.026	4.216ArgAsp: 4.216 ± 0.066	4.082ArgGlu: 4.082 ± 0.072	2.66ArgPhe: 2.66 ± 0.05	4.999ArgGly: 4.999 ± 0.071	2.202ArgHis: 2.202 ± 0.074	3.751ArgIle: 3.751 ± 0.062	1.966ArgLys: 1.966 ± 0.048	8.628ArgLeu: 8.628 ± 0.116	1.922ArgMet: 1.922 ± 0.042	2.08ArgAsn: 2.08 ± 0.046	3.269ArgPro: 3.269 ± 0.055	3.392ArgGln: 3.392 ± 0.059	5.585ArgArg: 5.585 ± 0.108	3.76ArgSer: 3.76 ± 0.078	3.328ArgThr: 3.328 ± 0.058	4.897ArgVal: 4.897 ± 0.068	1.424ArgTrp: 1.424 ± 0.039	2.324ArgTyr: 2.324 ± 0.061	0.0ArgXaa: 0.0 ± 0.0
Ser	7.057SerAla: 7.057 ± 0.107	0.452SerCys: 0.452 ± 0.02	2.996SerAsp: 2.996 ± 0.053	2.535SerGlu: 2.535 ± 0.051	1.807SerPhe: 1.807 ± 0.053	5.321SerGly: 5.321 ± 0.084	1.273SerHis: 1.273 ± 0.037	2.431SerIle: 2.431 ± 0.044	1.635SerLys: 1.635 ± 0.043	5.735SerLeu: 5.735 ± 0.09	1.228SerMet: 1.228 ± 0.035	1.698SerAsn: 1.698 ± 0.056	2.755SerPro: 2.755 ± 0.057	2.041SerGln: 2.041 ± 0.054	3.491SerArg: 3.491 ± 0.056	3.348SerSer: 3.348 ± 0.087	3.251SerThr: 3.251 ± 0.08	4.188SerVal: 4.188 ± 0.069	0.76SerTrp: 0.76 ± 0.03	1.427SerTyr: 1.427 ± 0.062	0.0SerXaa: 0.0 ± 0.0
Thr	6.183ThrAla: 6.183 ± 0.111	0.416ThrCys: 0.416 ± 0.023	2.726ThrAsp: 2.726 ± 0.049	2.151ThrGlu: 2.151 ± 0.051	1.542ThrPhe: 1.542 ± 0.041	4.328ThrGly: 4.328 ± 0.079	1.318ThrHis: 1.318 ± 0.034	2.141ThrIle: 2.141 ± 0.052	1.073ThrLys: 1.073 ± 0.038	6.839ThrLeu: 6.839 ± 0.092	1.061ThrMet: 1.061 ± 0.039	1.187ThrAsn: 1.187 ± 0.041	3.607ThrPro: 3.607 ± 0.065	2.154ThrGln: 2.154 ± 0.044	3.351ThrArg: 3.351 ± 0.072	2.767ThrSer: 2.767 ± 0.058	2.962ThrThr: 2.962 ± 0.071	3.865ThrVal: 3.865 ± 0.09	0.692ThrTrp: 0.692 ± 0.03	1.285ThrTyr: 1.285 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	9.177ValAla: 9.177 ± 0.12	0.723ValCys: 0.723 ± 0.023	4.131ValAsp: 4.131 ± 0.073	3.798ValGlu: 3.798 ± 0.075	2.371ValPhe: 2.371 ± 0.054	5.295ValGly: 5.295 ± 0.076	1.628ValHis: 1.628 ± 0.039	3.357ValIle: 3.357 ± 0.057	1.913ValLys: 1.913 ± 0.05	8.181ValLeu: 8.181 ± 0.112	1.581ValMet: 1.581 ± 0.041	2.033ValAsn: 2.033 ± 0.054	3.825ValPro: 3.825 ± 0.061	3.07ValGln: 3.07 ± 0.065	4.948ValArg: 4.948 ± 0.078	4.061ValSer: 4.061 ± 0.08	3.513ValThr: 3.513 ± 0.068	5.886ValVal: 5.886 ± 0.109	0.882ValTrp: 0.882 ± 0.027	1.644ValTyr: 1.644 ± 0.056	0.0ValXaa: 0.0 ± 0.0
Trp	1.182TrpAla: 1.182 ± 0.035	0.176TrpCys: 0.176 ± 0.013	0.646TrpAsp: 0.646 ± 0.028	0.529TrpGlu: 0.529 ± 0.022	0.556TrpPhe: 0.556 ± 0.022	0.899TrpGly: 0.899 ± 0.03	0.383TrpHis: 0.383 ± 0.017	0.68TrpIle: 0.68 ± 0.027	0.427TrpLys: 0.427 ± 0.02	2.138TrpLeu: 2.138 ± 0.052	0.431TrpMet: 0.431 ± 0.02	0.547TrpAsn: 0.547 ± 0.024	0.733TrpPro: 0.733 ± 0.031	0.89TrpGln: 0.89 ± 0.031	1.501TrpArg: 1.501 ± 0.044	0.943TrpSer: 0.943 ± 0.031	0.676TrpThr: 0.676 ± 0.03	0.908TrpVal: 0.908 ± 0.029	0.284TrpTrp: 0.284 ± 0.02	0.361TrpTyr: 0.361 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.337TyrAla: 3.337 ± 0.062	0.247TyrCys: 0.247 ± 0.017	1.471TyrAsp: 1.471 ± 0.06	1.044TyrGlu: 1.044 ± 0.033	0.927TyrPhe: 0.927 ± 0.033	2.136TyrGly: 2.136 ± 0.049	0.53TyrHis: 0.53 ± 0.024	0.798TyrIle: 0.798 ± 0.029	0.582TyrLys: 0.582 ± 0.027	2.652TyrLeu: 2.652 ± 0.054	0.471TyrMet: 0.471 ± 0.031	0.753TyrAsn: 0.753 ± 0.035	1.23TyrPro: 1.23 ± 0.034	0.972TyrGln: 0.972 ± 0.035	2.159TyrArg: 2.159 ± 0.049	1.344TyrSer: 1.344 ± 0.043	1.398TyrThr: 1.398 ± 0.054	1.871TyrVal: 1.871 ± 0.051	0.451TyrTrp: 0.451 ± 0.025	0.706TyrTyr: 0.706 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3190 proteins (1118321 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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