Amino acid dipepetide frequency for Herbiconiux ginsengi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.985AlaAla: 19.985 ± 0.213
0.567AlaCys: 0.567 ± 0.02
7.986AlaAsp: 7.986 ± 0.075
7.8AlaGlu: 7.8 ± 0.09
4.028AlaPhe: 4.028 ± 0.06
12.61AlaGly: 12.61 ± 0.118
2.491AlaHis: 2.491 ± 0.047
5.985AlaIle: 5.985 ± 0.074
2.494AlaLys: 2.494 ± 0.048
13.697AlaLeu: 13.697 ± 0.124
2.314AlaMet: 2.314 ± 0.04
2.469AlaAsn: 2.469 ± 0.038
6.78AlaPro: 6.78 ± 0.107
3.552AlaGln: 3.552 ± 0.056
8.669AlaArg: 8.669 ± 0.087
8.166AlaSer: 8.166 ± 0.089
7.964AlaThr: 7.964 ± 0.09
11.505AlaVal: 11.505 ± 0.112
1.723AlaTrp: 1.723 ± 0.033
2.412AlaTyr: 2.412 ± 0.04
0.0AlaXaa: 0.0 ± 0.0
Cys
0.616CysAla: 0.616 ± 0.022
0.041CysCys: 0.041 ± 0.006
0.296CysAsp: 0.296 ± 0.014
0.23CysGlu: 0.23 ± 0.013
0.164CysPhe: 0.164 ± 0.011
0.526CysGly: 0.526 ± 0.021
0.12CysHis: 0.12 ± 0.008
0.195CysIle: 0.195 ± 0.013
0.057CysLys: 0.057 ± 0.006
0.429CysLeu: 0.429 ± 0.017
0.071CysMet: 0.071 ± 0.007
0.103CysAsn: 0.103 ± 0.008
0.256CysPro: 0.256 ± 0.015
0.124CysGln: 0.124 ± 0.01
0.307CysArg: 0.307 ± 0.015
0.334CysSer: 0.334 ± 0.016
0.295CysThr: 0.295 ± 0.014
0.442CysVal: 0.442 ± 0.017
0.082CysTrp: 0.082 ± 0.008
0.101CysTyr: 0.101 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
8.79AspAla: 8.79 ± 0.093
0.244AspCys: 0.244 ± 0.014
4.396AspAsp: 4.396 ± 0.059
4.046AspGlu: 4.046 ± 0.057
1.817AspPhe: 1.817 ± 0.039
5.932AspGly: 5.932 ± 0.07
1.196AspHis: 1.196 ± 0.032
2.437AspIle: 2.437 ± 0.042
0.953AspLys: 0.953 ± 0.029
6.029AspLeu: 6.029 ± 0.064
0.686AspMet: 0.686 ± 0.021
0.978AspAsn: 0.978 ± 0.032
4.336AspPro: 4.336 ± 0.061
1.594AspGln: 1.594 ± 0.036
4.344AspArg: 4.344 ± 0.055
3.149AspSer: 3.149 ± 0.054
3.128AspThr: 3.128 ± 0.051
5.206AspVal: 5.206 ± 0.062
0.951AspTrp: 0.951 ± 0.026
1.357AspTyr: 1.357 ± 0.033
0.0AspXaa: 0.0 ± 0.0
Glu
6.622GluAla: 6.622 ± 0.078
0.23GluCys: 0.23 ± 0.014
2.005GluAsp: 2.005 ± 0.041
2.828GluGlu: 2.828 ± 0.053
1.866GluPhe: 1.866 ± 0.035
3.895GluGly: 3.895 ± 0.063
1.429GluHis: 1.429 ± 0.033
2.797GluIle: 2.797 ± 0.043
1.359GluLys: 1.359 ± 0.033
6.499GluLeu: 6.499 ± 0.087
0.894GluMet: 0.894 ± 0.024
1.492GluAsn: 1.492 ± 0.032
2.946GluPro: 2.946 ± 0.048
2.114GluGln: 2.114 ± 0.039
4.801GluArg: 4.801 ± 0.079
3.217GluSer: 3.217 ± 0.054
3.055GluThr: 3.055 ± 0.044
4.338GluVal: 4.338 ± 0.064
0.955GluTrp: 0.955 ± 0.028
1.162GluTyr: 1.162 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
4.37PheAla: 4.37 ± 0.057
0.173PheCys: 0.173 ± 0.011
2.546PheAsp: 2.546 ± 0.04
1.841PheGlu: 1.841 ± 0.043
1.116PhePhe: 1.116 ± 0.031
3.607PheGly: 3.607 ± 0.056
0.585PheHis: 0.585 ± 0.021
1.264PheIle: 1.264 ± 0.033
0.456PheLys: 0.456 ± 0.017
2.891PheLeu: 2.891 ± 0.052
0.426PheMet: 0.426 ± 0.018
0.692PheAsn: 0.692 ± 0.022
1.518PhePro: 1.518 ± 0.034
0.799PheGln: 0.799 ± 0.025
1.855PheArg: 1.855 ± 0.037
1.981PheSer: 1.981 ± 0.04
2.229PheThr: 2.229 ± 0.035
2.978PheVal: 2.978 ± 0.044
0.492PheTrp: 0.492 ± 0.02
0.663PheTyr: 0.663 ± 0.024
0.0PheXaa: 0.0 ± 0.0
Gly
10.992GlyAla: 10.992 ± 0.108
0.6GlyCys: 0.6 ± 0.02
5.057GlyAsp: 5.057 ± 0.066
4.668GlyGlu: 4.668 ± 0.068
3.426GlyPhe: 3.426 ± 0.054
8.111GlyGly: 8.111 ± 0.102
1.875GlyHis: 1.875 ± 0.036
4.827GlyIle: 4.827 ± 0.063
1.97GlyLys: 1.97 ± 0.044
8.804GlyLeu: 8.804 ± 0.091
1.775GlyMet: 1.775 ± 0.038
1.896GlyAsn: 1.896 ± 0.04
3.995GlyPro: 3.995 ± 0.06
2.488GlyGln: 2.488 ± 0.044
6.199GlyArg: 6.199 ± 0.085
6.135GlySer: 6.135 ± 0.082
5.706GlyThr: 5.706 ± 0.084
8.056GlyVal: 8.056 ± 0.088
1.586GlyTrp: 1.586 ± 0.034
2.266GlyTyr: 2.266 ± 0.046
0.0GlyXaa: 0.0 ± 0.0
His
2.211HisAla: 2.211 ± 0.042
0.116HisCys: 0.116 ± 0.009
1.403HisAsp: 1.403 ± 0.033
1.122HisGlu: 1.122 ± 0.033
0.595HisPhe: 0.595 ± 0.018
1.924HisGly: 1.924 ± 0.039
0.562HisHis: 0.562 ± 0.023
0.713HisIle: 0.713 ± 0.02
0.268HisLys: 0.268 ± 0.011
2.056HisLeu: 2.056 ± 0.041
0.298HisMet: 0.298 ± 0.013
0.353HisAsn: 0.353 ± 0.016
1.596HisPro: 1.596 ± 0.037
0.503HisGln: 0.503 ± 0.019
1.533HisArg: 1.533 ± 0.034
1.053HisSer: 1.053 ± 0.03
1.066HisThr: 1.066 ± 0.027
1.529HisVal: 1.529 ± 0.035
0.302HisTrp: 0.302 ± 0.016
0.466HisTyr: 0.466 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
7.053IleAla: 7.053 ± 0.088
0.245IleCys: 0.245 ± 0.013
3.668IleAsp: 3.668 ± 0.059
2.798IleGlu: 2.798 ± 0.05
1.207IlePhe: 1.207 ± 0.038
4.78IleGly: 4.78 ± 0.072
0.706IleHis: 0.706 ± 0.02
1.767IleIle: 1.767 ± 0.046
0.752IleLys: 0.752 ± 0.024
3.81IleLeu: 3.81 ± 0.059
0.574IleMet: 0.574 ± 0.021
0.947IleAsn: 0.947 ± 0.027
2.427IlePro: 2.427 ± 0.038
1.081IleGln: 1.081 ± 0.035
2.834IleArg: 2.834 ± 0.043
2.55IleSer: 2.55 ± 0.044
2.898IleThr: 2.898 ± 0.052
4.822IleVal: 4.822 ± 0.069
0.529IleTrp: 0.529 ± 0.02
0.804IleTyr: 0.804 ± 0.028
0.0IleXaa: 0.0 ± 0.0
Lys
2.413LysAla: 2.413 ± 0.049
0.054LysCys: 0.054 ± 0.007
1.009LysAsp: 1.009 ± 0.032
0.986LysGlu: 0.986 ± 0.03
0.504LysPhe: 0.504 ± 0.018
1.429LysGly: 1.429 ± 0.031
0.438LysHis: 0.438 ± 0.018
0.944LysIle: 0.944 ± 0.027
0.72LysLys: 0.72 ± 0.026
1.809LysLeu: 1.809 ± 0.039
0.33LysMet: 0.33 ± 0.016
0.574LysAsn: 0.574 ± 0.019
1.17LysPro: 1.17 ± 0.031
0.681LysGln: 0.681 ± 0.023
1.397LysArg: 1.397 ± 0.036
1.22LysSer: 1.22 ± 0.03
1.285LysThr: 1.285 ± 0.037
1.559LysVal: 1.559 ± 0.041
0.271LysTrp: 0.271 ± 0.014
0.453LysTyr: 0.453 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
14.274LeuAla: 14.274 ± 0.116
0.497LeuCys: 0.497 ± 0.02
6.776LeuAsp: 6.776 ± 0.071
5.037LeuGlu: 5.037 ± 0.071
3.014LeuPhe: 3.014 ± 0.064
9.253LeuGly: 9.253 ± 0.094
1.885LeuHis: 1.885 ± 0.038
4.53LeuIle: 4.53 ± 0.076
1.703LeuLys: 1.703 ± 0.039
10.118LeuLeu: 10.118 ± 0.124
1.495LeuMet: 1.495 ± 0.03
1.95LeuAsn: 1.95 ± 0.039
5.523LeuPro: 5.523 ± 0.07
2.471LeuGln: 2.471 ± 0.04
6.908LeuArg: 6.908 ± 0.088
6.074LeuSer: 6.074 ± 0.067
6.325LeuThr: 6.325 ± 0.063
9.263LeuVal: 9.263 ± 0.104
1.22LeuTrp: 1.22 ± 0.028
1.67LeuTyr: 1.67 ± 0.037
0.0LeuXaa: 0.0 ± 0.0
Met
2.004MetAla: 2.004 ± 0.042
0.089MetCys: 0.089 ± 0.007
0.661MetAsp: 0.661 ± 0.022
0.552MetGlu: 0.552 ± 0.017
0.489MetPhe: 0.489 ± 0.019
1.118MetGly: 1.118 ± 0.03
0.298MetHis: 0.298 ± 0.014
0.834MetIle: 0.834 ± 0.026
0.438MetLys: 0.438 ± 0.019
1.714MetLeu: 1.714 ± 0.034
0.279MetMet: 0.279 ± 0.014
0.499MetAsn: 0.499 ± 0.016
1.058MetPro: 1.058 ± 0.024
0.475MetGln: 0.475 ± 0.019
1.244MetArg: 1.244 ± 0.031
1.506MetSer: 1.506 ± 0.034
1.665MetThr: 1.665 ± 0.034
1.218MetVal: 1.218 ± 0.029
0.164MetTrp: 0.164 ± 0.01
0.266MetTyr: 0.266 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
2.632AsnAla: 2.632 ± 0.046
0.116AsnCys: 0.116 ± 0.008
1.328AsnAsp: 1.328 ± 0.033
1.051AsnGlu: 1.051 ± 0.028
0.673AsnPhe: 0.673 ± 0.022
2.189AsnGly: 2.189 ± 0.044
0.38AsnHis: 0.38 ± 0.017
0.886AsnIle: 0.886 ± 0.028
0.406AsnLys: 0.406 ± 0.019
2.071AsnLeu: 2.071 ± 0.038
0.315AsnMet: 0.315 ± 0.014
0.505AsnAsn: 0.505 ± 0.019
1.732AsnPro: 1.732 ± 0.036
0.61AsnGln: 0.61 ± 0.021
1.354AsnArg: 1.354 ± 0.029
1.155AsnSer: 1.155 ± 0.033
1.279AsnThr: 1.279 ± 0.032
1.767AsnVal: 1.767 ± 0.034
0.354AsnTrp: 0.354 ± 0.016
0.577AsnTyr: 0.577 ± 0.02
0.0AsnXaa: 0.0 ± 0.0
Pro
7.652ProAla: 7.652 ± 0.103
0.186ProCys: 0.186 ± 0.012
4.142ProAsp: 4.142 ± 0.06
3.755ProGlu: 3.755 ± 0.049
1.792ProPhe: 1.792 ± 0.036
5.32ProGly: 5.32 ± 0.063
1.067ProHis: 1.067 ± 0.028
2.236ProIle: 2.236 ± 0.042
1.017ProLys: 1.017 ± 0.029
4.815ProLeu: 4.815 ± 0.066
0.849ProMet: 0.849 ± 0.027
1.178ProAsn: 1.178 ± 0.032
2.584ProPro: 2.584 ± 0.061
1.406ProGln: 1.406 ± 0.032
3.212ProArg: 3.212 ± 0.046
3.513ProSer: 3.513 ± 0.056
3.666ProThr: 3.666 ± 0.061
5.052ProVal: 5.052 ± 0.07
0.802ProTrp: 0.802 ± 0.022
1.062ProTyr: 1.062 ± 0.031
0.0ProXaa: 0.0 ± 0.0
Gln
3.35GlnAla: 3.35 ± 0.048
0.11GlnCys: 0.11 ± 0.009
1.146GlnAsp: 1.146 ± 0.028
1.183GlnGlu: 1.183 ± 0.03
0.945GlnPhe: 0.945 ± 0.026
2.007GlnGly: 2.007 ± 0.04
0.588GlnHis: 0.588 ± 0.017
1.408GlnIle: 1.408 ± 0.026
0.702GlnLys: 0.702 ± 0.023
3.212GlnLeu: 3.212 ± 0.047
0.451GlnMet: 0.451 ± 0.02
0.75GlnAsn: 0.75 ± 0.024
1.515GlnPro: 1.515 ± 0.032
1.075GlnGln: 1.075 ± 0.033
2.104GlnArg: 2.104 ± 0.038
1.656GlnSer: 1.656 ± 0.039
1.571GlnThr: 1.571 ± 0.033
2.337GlnVal: 2.337 ± 0.042
0.438GlnTrp: 0.438 ± 0.018
0.66GlnTyr: 0.66 ± 0.027
0.0GlnXaa: 0.0 ± 0.0
Arg
8.369ArgAla: 8.369 ± 0.097
0.275ArgCys: 0.275 ± 0.014
3.982ArgAsp: 3.982 ± 0.057
4.037ArgGlu: 4.037 ± 0.063
2.49ArgPhe: 2.49 ± 0.044
5.046ArgGly: 5.046 ± 0.068
1.532ArgHis: 1.532 ± 0.034
3.591ArgIle: 3.591 ± 0.047
1.289ArgLys: 1.289 ± 0.034
6.922ArgLeu: 6.922 ± 0.081
1.711ArgMet: 1.711 ± 0.039
1.353ArgAsn: 1.353 ± 0.035
3.628ArgPro: 3.628 ± 0.063
1.894ArgGln: 1.894 ± 0.041
5.958ArgArg: 5.958 ± 0.079
4.41ArgSer: 4.41 ± 0.062
3.967ArgThr: 3.967 ± 0.059
5.642ArgVal: 5.642 ± 0.063
1.085ArgTrp: 1.085 ± 0.026
1.54ArgTyr: 1.54 ± 0.036
0.0ArgXaa: 0.0 ± 0.0
Ser
8.005SerAla: 8.005 ± 0.092
0.285SerCys: 0.285 ± 0.016
3.505SerAsp: 3.505 ± 0.057
2.978SerGlu: 2.978 ± 0.051
2.073SerPhe: 2.073 ± 0.039
6.575SerGly: 6.575 ± 0.095
1.086SerHis: 1.086 ± 0.028
3.012SerIle: 3.012 ± 0.047
1.164SerLys: 1.164 ± 0.033
5.721SerLeu: 5.721 ± 0.068
1.163SerMet: 1.163 ± 0.022
1.338SerAsn: 1.338 ± 0.035
3.415SerPro: 3.415 ± 0.048
1.5SerGln: 1.5 ± 0.036
4.02SerArg: 4.02 ± 0.057
4.122SerSer: 4.122 ± 0.07
4.176SerThr: 4.176 ± 0.058
5.257SerVal: 5.257 ± 0.066
0.983SerTrp: 0.983 ± 0.027
1.427SerTyr: 1.427 ± 0.031
0.0SerXaa: 0.0 ± 0.0
Thr
8.109ThrAla: 8.109 ± 0.09
0.27ThrCys: 0.27 ± 0.016
3.86ThrAsp: 3.86 ± 0.053
3.126ThrGlu: 3.126 ± 0.046
1.881ThrPhe: 1.881 ± 0.039
5.933ThrGly: 5.933 ± 0.077
1.149ThrHis: 1.149 ± 0.032
3.044ThrIle: 3.044 ± 0.053
1.232ThrLys: 1.232 ± 0.031
6.134ThrLeu: 6.134 ± 0.067
0.994ThrMet: 0.994 ± 0.026
1.321ThrAsn: 1.321 ± 0.035
4.277ThrPro: 4.277 ± 0.068
1.451ThrGln: 1.451 ± 0.033
3.751ThrArg: 3.751 ± 0.055
3.801ThrSer: 3.801 ± 0.06
4.249ThrThr: 4.249 ± 0.076
6.135ThrVal: 6.135 ± 0.077
0.897ThrTrp: 0.897 ± 0.029
1.138ThrTyr: 1.138 ± 0.03
0.0ThrXaa: 0.0 ± 0.0
Val
11.813ValAla: 11.813 ± 0.101
0.475ValCys: 0.475 ± 0.017
5.671ValAsp: 5.671 ± 0.068
4.704ValGlu: 4.704 ± 0.065
3.043ValPhe: 3.043 ± 0.047
7.147ValGly: 7.147 ± 0.077
1.63ValHis: 1.63 ± 0.031
4.393ValIle: 4.393 ± 0.072
1.602ValLys: 1.602 ± 0.038
9.298ValLeu: 9.298 ± 0.096
1.378ValMet: 1.378 ± 0.028
1.983ValAsn: 1.983 ± 0.043
4.78ValPro: 4.78 ± 0.058
2.195ValGln: 2.195 ± 0.04
5.461ValArg: 5.461 ± 0.065
5.489ValSer: 5.489 ± 0.07
6.054ValThr: 6.054 ± 0.078
9.211ValVal: 9.211 ± 0.09
1.104ValTrp: 1.104 ± 0.027
1.631ValTyr: 1.631 ± 0.03
0.0ValXaa: 0.0 ± 0.0
Trp
1.581TrpAla: 1.581 ± 0.036
0.095TrpCys: 0.095 ± 0.008
0.699TrpAsp: 0.699 ± 0.026
0.661TrpGlu: 0.661 ± 0.023
0.553TrpPhe: 0.553 ± 0.019
1.063TrpGly: 1.063 ± 0.027
0.324TrpHis: 0.324 ± 0.017
0.714TrpIle: 0.714 ± 0.025
0.325TrpLys: 0.325 ± 0.016
1.699TrpLeu: 1.699 ± 0.037
0.307TrpMet: 0.307 ± 0.014
0.512TrpAsn: 0.512 ± 0.02
0.678TrpPro: 0.678 ± 0.024
0.572TrpGln: 0.572 ± 0.021
1.118TrpArg: 1.118 ± 0.031
0.998TrpSer: 0.998 ± 0.025
0.969TrpThr: 0.969 ± 0.03
1.092TrpVal: 1.092 ± 0.024
0.329TrpTrp: 0.329 ± 0.018
0.313TrpTyr: 0.313 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.354TyrAla: 2.354 ± 0.039
0.12TyrCys: 0.12 ± 0.008
1.434TyrAsp: 1.434 ± 0.044
1.101TyrGlu: 1.101 ± 0.03
0.805TyrPhe: 0.805 ± 0.027
1.967TyrGly: 1.967 ± 0.036
0.329TyrHis: 0.329 ± 0.015
0.676TyrIle: 0.676 ± 0.026
0.339TyrLys: 0.339 ± 0.016
2.257TyrLeu: 2.257 ± 0.044
0.257TyrMet: 0.257 ± 0.014
0.487TyrAsn: 0.487 ± 0.021
1.091TyrPro: 1.091 ± 0.028
0.625TyrGln: 0.625 ± 0.022
1.653TyrArg: 1.653 ± 0.036
1.275TyrSer: 1.275 ± 0.032
1.208TyrThr: 1.208 ± 0.03
1.651TyrVal: 1.651 ± 0.034
0.337TyrTrp: 0.337 ± 0.015
0.497TyrTyr: 0.497 ± 0.02
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4507 proteins (1471252 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski