Amino acid dipepetide frequency for Chandiru virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.342AlaAla: 5.342 ± 1.712
1.526AlaCys: 1.526 ± 0.509
1.781AlaAsp: 1.781 ± 0.656
3.307AlaGlu: 3.307 ± 0.599
3.053AlaPhe: 3.053 ± 1.363
3.816AlaGly: 3.816 ± 1.132
0.509AlaHis: 0.509 ± 0.175
4.325AlaIle: 4.325 ± 2.261
2.289AlaLys: 2.289 ± 1.512
3.816AlaLeu: 3.816 ± 1.223
1.272AlaMet: 1.272 ± 1.111
0.254AlaAsn: 0.254 ± 0.169
1.526AlaPro: 1.526 ± 0.525
1.272AlaGln: 1.272 ± 0.614
1.781AlaArg: 1.781 ± 0.268
3.561AlaSer: 3.561 ± 0.983
2.544AlaThr: 2.544 ± 0.838
2.798AlaVal: 2.798 ± 0.818
0.509AlaTrp: 0.509 ± 0.614
1.781AlaTyr: 1.781 ± 1.399
0.0AlaXaa: 0.0 ± 0.0
Cys
1.526CysAla: 1.526 ± 0.75
0.509CysCys: 0.509 ± 0.339
0.763CysAsp: 0.763 ± 0.504
3.053CysGlu: 3.053 ± 1.797
2.289CysPhe: 2.289 ± 0.761
0.763CysGly: 0.763 ± 0.697
0.509CysHis: 0.509 ± 0.465
1.781CysIle: 1.781 ± 0.972
2.544CysLys: 2.544 ± 1.105
2.544CysLeu: 2.544 ± 0.838
0.509CysMet: 0.509 ± 0.339
1.272CysAsn: 1.272 ± 0.552
0.509CysPro: 0.509 ± 0.175
1.526CysGln: 1.526 ± 0.505
1.272CysArg: 1.272 ± 0.639
3.053CysSer: 3.053 ± 0.779
1.526CysThr: 1.526 ± 0.75
0.763CysVal: 0.763 ± 0.697
0.0CysTrp: 0.0 ± 0.0
0.509CysTyr: 0.509 ± 0.175
0.0CysXaa: 0.0 ± 0.0
Asp
3.053AspAla: 3.053 ± 1.979
1.272AspCys: 1.272 ± 1.162
5.851AspAsp: 5.851 ± 1.234
4.325AspGlu: 4.325 ± 1.476
3.053AspPhe: 3.053 ± 0.67
3.053AspGly: 3.053 ± 0.591
1.526AspHis: 1.526 ± 0.509
4.07AspIle: 4.07 ± 1.186
3.816AspLys: 3.816 ± 0.632
6.105AspLeu: 6.105 ± 1.941
1.018AspMet: 1.018 ± 0.522
2.035AspAsn: 2.035 ± 0.65
1.781AspPro: 1.781 ± 0.379
1.781AspGln: 1.781 ± 0.643
2.035AspArg: 2.035 ± 0.643
5.088AspSer: 5.088 ± 1.375
1.526AspThr: 1.526 ± 0.766
2.035AspVal: 2.035 ± 0.708
1.018AspTrp: 1.018 ± 0.435
2.798AspTyr: 2.798 ± 0.609
0.0AspXaa: 0.0 ± 0.0
Glu
2.544GluAla: 2.544 ± 0.651
1.018GluCys: 1.018 ± 0.35
5.088GluAsp: 5.088 ± 1.546
5.597GluGlu: 5.597 ± 1.235
4.579GluPhe: 4.579 ± 0.736
4.07GluGly: 4.07 ± 0.576
0.254GluHis: 0.254 ± 0.169
6.868GluIle: 6.868 ± 0.505
4.833GluLys: 4.833 ± 1.519
6.614GluLeu: 6.614 ± 0.805
0.763GluMet: 0.763 ± 0.508
3.053GluAsn: 3.053 ± 0.73
2.544GluPro: 2.544 ± 0.388
1.272GluGln: 1.272 ± 0.652
3.561GluArg: 3.561 ± 0.689
6.36GluSer: 6.36 ± 1.242
3.307GluThr: 3.307 ± 1.051
4.07GluVal: 4.07 ± 0.219
0.254GluTrp: 0.254 ± 0.169
2.798GluTyr: 2.798 ± 0.616
0.0GluXaa: 0.0 ± 0.0
Phe
2.544PheAla: 2.544 ± 0.82
1.526PheCys: 1.526 ± 0.75
2.798PheAsp: 2.798 ± 1.624
2.035PheGlu: 2.035 ± 0.65
2.798PhePhe: 2.798 ± 0.57
1.018PheGly: 1.018 ± 0.678
1.272PheHis: 1.272 ± 0.344
3.561PheIle: 3.561 ± 0.164
3.053PheLys: 3.053 ± 0.482
5.342PheLeu: 5.342 ± 0.94
1.781PheMet: 1.781 ± 0.325
2.798PheAsn: 2.798 ± 0.571
1.526PhePro: 1.526 ± 0.735
1.018PheGln: 1.018 ± 0.395
3.053PheArg: 3.053 ± 0.714
4.579PheSer: 4.579 ± 1.044
2.289PheThr: 2.289 ± 0.669
3.561PheVal: 3.561 ± 1.133
0.509PheTrp: 0.509 ± 0.175
0.254PheTyr: 0.254 ± 0.169
0.0PheXaa: 0.0 ± 0.0
Gly
5.088GlyAla: 5.088 ± 0.686
1.272GlyCys: 1.272 ± 0.827
2.798GlyAsp: 2.798 ± 0.364
3.561GlyGlu: 3.561 ± 0.769
4.325GlyPhe: 4.325 ± 0.792
3.561GlyGly: 3.561 ± 0.564
1.526GlyHis: 1.526 ± 0.82
4.325GlyIle: 4.325 ± 0.969
4.07GlyLys: 4.07 ± 1.152
3.816GlyLeu: 3.816 ± 1.419
1.526GlyMet: 1.526 ± 0.518
3.307GlyAsn: 3.307 ± 1.416
2.035GlyPro: 2.035 ± 0.549
1.526GlyGln: 1.526 ± 0.86
2.289GlyArg: 2.289 ± 1.525
4.579GlySer: 4.579 ± 1.471
2.798GlyThr: 2.798 ± 0.87
5.088GlyVal: 5.088 ± 1.09
0.763GlyTrp: 0.763 ± 0.697
1.526GlyTyr: 1.526 ± 0.746
0.0GlyXaa: 0.0 ± 0.0
His
0.763HisAla: 0.763 ± 0.697
0.763HisCys: 0.763 ± 0.375
1.018HisAsp: 1.018 ± 0.395
0.763HisGlu: 0.763 ± 0.504
1.272HisPhe: 1.272 ± 0.552
1.526HisGly: 1.526 ± 0.715
1.018HisHis: 1.018 ± 0.599
2.798HisIle: 2.798 ± 0.521
1.781HisLys: 1.781 ± 0.643
2.544HisLeu: 2.544 ± 0.968
0.509HisMet: 0.509 ± 0.175
0.0HisAsn: 0.0 ± 0.0
1.018HisPro: 1.018 ± 0.601
0.763HisGln: 0.763 ± 0.254
1.272HisArg: 1.272 ± 0.537
1.781HisSer: 1.781 ± 0.364
1.272HisThr: 1.272 ± 0.639
1.272HisVal: 1.272 ± 0.403
0.0HisTrp: 0.0 ± 0.0
1.018HisTyr: 1.018 ± 0.395
0.0HisXaa: 0.0 ± 0.0
Ile
3.053IleAla: 3.053 ± 0.961
2.289IleCys: 2.289 ± 0.539
5.851IleAsp: 5.851 ± 1.311
3.816IleGlu: 3.816 ± 0.876
1.272IlePhe: 1.272 ± 0.847
4.07IleGly: 4.07 ± 1.301
0.763IleHis: 0.763 ± 0.375
5.342IleIle: 5.342 ± 1.083
6.105IleLys: 6.105 ± 1.396
5.851IleLeu: 5.851 ± 0.811
3.561IleMet: 3.561 ± 0.613
2.798IleAsn: 2.798 ± 0.89
4.579IlePro: 4.579 ± 0.66
2.035IleGln: 2.035 ± 1.047
4.07IleArg: 4.07 ± 0.857
8.14IleSer: 8.14 ± 1.362
3.816IleThr: 3.816 ± 0.903
3.561IleVal: 3.561 ± 0.564
0.254IleTrp: 0.254 ± 0.169
2.289IleTyr: 2.289 ± 0.763
0.0IleXaa: 0.0 ± 0.0
Lys
3.307LysAla: 3.307 ± 0.786
3.307LysCys: 3.307 ± 0.717
2.798LysAsp: 2.798 ± 0.902
4.325LysGlu: 4.325 ± 1.474
1.781LysPhe: 1.781 ± 0.643
4.07LysGly: 4.07 ± 2.388
1.272LysHis: 1.272 ± 0.847
5.597LysIle: 5.597 ± 0.888
5.851LysLys: 5.851 ± 0.794
8.395LysLeu: 8.395 ± 0.534
2.544LysMet: 2.544 ± 1.353
3.053LysAsn: 3.053 ± 1.64
2.289LysPro: 2.289 ± 0.512
2.798LysGln: 2.798 ± 0.818
3.816LysArg: 3.816 ± 0.578
5.088LysSer: 5.088 ± 1.546
4.07LysThr: 4.07 ± 0.857
4.07LysVal: 4.07 ± 0.537
1.526LysTrp: 1.526 ± 0.95
2.544LysTyr: 2.544 ± 1.074
0.0LysXaa: 0.0 ± 0.0
Leu
4.07LeuAla: 4.07 ± 0.656
2.035LeuCys: 2.035 ± 0.708
5.342LeuAsp: 5.342 ± 1.027
4.325LeuGlu: 4.325 ± 1.037
4.325LeuPhe: 4.325 ± 1.799
6.614LeuGly: 6.614 ± 0.797
2.289LeuHis: 2.289 ± 0.445
5.597LeuIle: 5.597 ± 1.369
6.614LeuLys: 6.614 ± 0.995
4.579LeuLeu: 4.579 ± 1.034
2.544LeuMet: 2.544 ± 0.647
3.307LeuAsn: 3.307 ± 1.151
3.307LeuPro: 3.307 ± 1.45
3.561LeuGln: 3.561 ± 0.989
6.36LeuArg: 6.36 ± 0.644
11.702LeuSer: 11.702 ± 1.615
4.833LeuThr: 4.833 ± 0.55
4.579LeuVal: 4.579 ± 1.182
0.254LeuTrp: 0.254 ± 0.169
2.289LeuTyr: 2.289 ± 0.673
0.0LeuXaa: 0.0 ± 0.0
Met
0.763MetAla: 0.763 ± 0.375
0.254MetCys: 0.254 ± 0.169
2.035MetAsp: 2.035 ± 1.054
3.816MetGlu: 3.816 ± 0.75
1.272MetPhe: 1.272 ± 0.403
1.272MetGly: 1.272 ± 0.552
1.272MetHis: 1.272 ± 0.425
1.526MetIle: 1.526 ± 0.48
2.289MetLys: 2.289 ± 0.735
2.798MetLeu: 2.798 ± 0.828
2.544MetMet: 2.544 ± 1.361
0.763MetAsn: 0.763 ± 0.504
0.0MetPro: 0.0 ± 0.0
1.272MetGln: 1.272 ± 0.425
1.272MetArg: 1.272 ± 0.358
3.053MetSer: 3.053 ± 1.467
2.035MetThr: 2.035 ± 0.285
2.035MetVal: 2.035 ± 0.869
0.254MetTrp: 0.254 ± 0.232
0.254MetTyr: 0.254 ± 0.232
0.0MetXaa: 0.0 ± 0.0
Asn
1.272AsnAla: 1.272 ± 0.681
0.509AsnCys: 0.509 ± 0.175
1.526AsnAsp: 1.526 ± 0.525
3.561AsnGlu: 3.561 ± 1.658
1.526AsnPhe: 1.526 ± 0.413
2.544AsnGly: 2.544 ± 0.982
0.763AsnHis: 0.763 ± 0.254
2.289AsnIle: 2.289 ± 0.761
4.07AsnLys: 4.07 ± 0.703
5.851AsnLeu: 5.851 ± 0.8
1.526AsnMet: 1.526 ± 1.729
1.781AsnAsn: 1.781 ± 0.68
3.307AsnPro: 3.307 ± 1.272
1.272AsnGln: 1.272 ± 0.537
2.798AsnArg: 2.798 ± 0.394
3.816AsnSer: 3.816 ± 1.395
1.526AsnThr: 1.526 ± 1.016
0.254AsnVal: 0.254 ± 0.551
0.509AsnTrp: 0.509 ± 0.552
0.763AsnTyr: 0.763 ± 0.678
0.0AsnXaa: 0.0 ± 0.0
Pro
1.526ProAla: 1.526 ± 0.735
1.018ProCys: 1.018 ± 0.971
1.781ProAsp: 1.781 ± 0.325
3.307ProGlu: 3.307 ± 1.34
2.544ProPhe: 2.544 ± 0.982
1.781ProGly: 1.781 ± 0.566
1.526ProHis: 1.526 ± 0.829
2.035ProIle: 2.035 ± 0.576
2.035ProLys: 2.035 ± 0.708
3.053ProLeu: 3.053 ± 0.591
0.763ProMet: 0.763 ± 0.375
1.781ProAsn: 1.781 ± 0.364
0.763ProPro: 0.763 ± 0.564
1.526ProGln: 1.526 ± 0.75
2.035ProArg: 2.035 ± 1.813
3.561ProSer: 3.561 ± 2.213
1.781ProThr: 1.781 ± 0.364
1.272ProVal: 1.272 ± 1.056
1.272ProTrp: 1.272 ± 0.847
1.272ProTyr: 1.272 ± 0.358
0.0ProXaa: 0.0 ± 0.0
Gln
1.781GlnAla: 1.781 ± 1.633
1.018GlnCys: 1.018 ± 0.599
1.781GlnAsp: 1.781 ± 1.289
3.307GlnGlu: 3.307 ± 1.051
0.509GlnPhe: 0.509 ± 0.575
1.781GlnGly: 1.781 ± 0.916
1.272GlnHis: 1.272 ± 0.403
4.07GlnIle: 4.07 ± 1.317
2.035GlnLys: 2.035 ± 1.355
1.272GlnLeu: 1.272 ± 0.887
1.781GlnMet: 1.781 ± 0.325
1.526GlnAsn: 1.526 ± 0.267
0.763GlnPro: 0.763 ± 0.564
1.018GlnGln: 1.018 ± 0.678
1.272GlnArg: 1.272 ± 0.652
2.289GlnSer: 2.289 ± 0.945
1.018GlnThr: 1.018 ± 0.35
2.035GlnVal: 2.035 ± 0.772
0.0GlnTrp: 0.0 ± 0.0
0.254GlnTyr: 0.254 ± 0.169
0.0GlnXaa: 0.0 ± 0.0
Arg
1.781ArgAla: 1.781 ± 0.325
1.526ArgCys: 1.526 ± 1.058
2.289ArgAsp: 2.289 ± 0.539
5.088ArgGlu: 5.088 ± 1.083
1.526ArgPhe: 1.526 ± 0.509
3.561ArgGly: 3.561 ± 1.958
1.018ArgHis: 1.018 ± 0.395
3.307ArgIle: 3.307 ± 0.599
3.816ArgLys: 3.816 ± 0.04
2.798ArgLeu: 2.798 ± 0.521
1.018ArgMet: 1.018 ± 0.492
1.781ArgAsn: 1.781 ± 0.926
1.781ArgPro: 1.781 ± 0.379
1.018ArgGln: 1.018 ± 0.522
1.272ArgArg: 1.272 ± 0.827
6.105ArgSer: 6.105 ± 1.874
1.781ArgThr: 1.781 ± 0.916
4.325ArgVal: 4.325 ± 1.263
1.526ArgTrp: 1.526 ± 0.267
2.289ArgTyr: 2.289 ± 1.079
0.0ArgXaa: 0.0 ± 0.0
Ser
4.325SerAla: 4.325 ± 0.849
3.307SerCys: 3.307 ± 2.024
5.597SerAsp: 5.597 ± 1.109
4.833SerGlu: 4.833 ± 1.519
4.325SerPhe: 4.325 ± 2.923
4.833SerGly: 4.833 ± 0.4
3.561SerHis: 3.561 ± 0.923
6.36SerIle: 6.36 ± 2.268
6.36SerLys: 6.36 ± 1.375
11.193SerLeu: 11.193 ± 1.177
1.526SerMet: 1.526 ± 0.509
4.833SerAsn: 4.833 ± 0.584
3.816SerPro: 3.816 ± 0.876
1.526SerGln: 1.526 ± 0.509
5.088SerArg: 5.088 ± 1.944
9.412SerSer: 9.412 ± 1.543
5.088SerThr: 5.088 ± 0.779
4.579SerVal: 4.579 ± 1.084
2.798SerTrp: 2.798 ± 1.197
2.798SerTyr: 2.798 ± 0.364
0.0SerXaa: 0.0 ± 0.0
Thr
1.781ThrAla: 1.781 ± 0.714
1.526ThrCys: 1.526 ± 0.505
3.307ThrAsp: 3.307 ± 0.599
3.053ThrGlu: 3.053 ± 0.484
1.781ThrPhe: 1.781 ± 0.671
5.342ThrGly: 5.342 ± 2.083
0.763ThrHis: 0.763 ± 0.375
5.088ThrIle: 5.088 ± 1.083
2.798ThrLys: 2.798 ± 0.902
5.597ThrLeu: 5.597 ± 0.527
1.272ThrMet: 1.272 ± 0.42
2.544ThrAsn: 2.544 ± 1.105
1.781ThrPro: 1.781 ± 1.4
1.018ThrGln: 1.018 ± 0.395
1.272ThrArg: 1.272 ± 1.513
4.579ThrSer: 4.579 ± 1.025
1.272ThrThr: 1.272 ± 0.639
2.544ThrVal: 2.544 ± 0.39
0.0ThrTrp: 0.0 ± 0.0
0.763ThrTyr: 0.763 ± 0.375
0.0ThrXaa: 0.0 ± 0.0
Val
1.272ValAla: 1.272 ± 0.425
1.272ValCys: 1.272 ± 1.162
2.544ValAsp: 2.544 ± 0.361
4.833ValGlu: 4.833 ± 1.768
3.053ValPhe: 3.053 ± 0.714
2.544ValGly: 2.544 ± 0.805
1.272ValHis: 1.272 ± 0.403
2.798ValIle: 2.798 ± 0.805
4.579ValLys: 4.579 ± 2.053
3.561ValLeu: 3.561 ± 0.164
1.781ValMet: 1.781 ± 0.379
2.289ValAsn: 2.289 ± 1.109
1.018ValPro: 1.018 ± 0.522
3.816ValGln: 3.816 ± 1.598
3.816ValArg: 3.816 ± 1.208
5.597ValSer: 5.597 ± 0.645
3.561ValThr: 3.561 ± 0.65
3.307ValVal: 3.307 ± 1.051
1.018ValTrp: 1.018 ± 0.395
2.798ValTyr: 2.798 ± 0.521
0.0ValXaa: 0.0 ± 0.0
Trp
0.763TrpAla: 0.763 ± 0.254
0.254TrpCys: 0.254 ± 0.169
1.018TrpAsp: 1.018 ± 0.492
0.509TrpGlu: 0.509 ± 0.552
0.254TrpPhe: 0.254 ± 0.169
1.272TrpGly: 1.272 ± 1.521
0.0TrpHis: 0.0 ± 0.0
0.509TrpIle: 0.509 ± 0.339
0.509TrpLys: 0.509 ± 0.339
0.763TrpLeu: 0.763 ± 0.375
0.763TrpMet: 0.763 ± 0.254
0.763TrpAsn: 0.763 ± 0.254
0.509TrpPro: 0.509 ± 0.486
0.254TrpGln: 0.254 ± 0.169
0.509TrpArg: 0.509 ± 0.339
1.272TrpSer: 1.272 ± 0.358
1.272TrpThr: 1.272 ± 0.358
1.781TrpVal: 1.781 ± 1.013
0.254TrpTrp: 0.254 ± 0.169
0.254TrpTyr: 0.254 ± 0.169
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.509TyrAla: 0.509 ± 0.175
1.018TyrCys: 1.018 ± 0.599
1.272TyrAsp: 1.272 ± 0.946
2.035TyrGlu: 2.035 ± 1.263
1.781TyrPhe: 1.781 ± 0.566
2.289TyrGly: 2.289 ± 0.735
0.763TyrHis: 0.763 ± 0.508
1.272TyrIle: 1.272 ± 0.552
3.053TyrLys: 3.053 ± 0.534
2.035TyrLeu: 2.035 ± 0.79
1.526TyrMet: 1.526 ± 0.509
1.781TyrAsn: 1.781 ± 0.268
1.781TyrPro: 1.781 ± 0.671
0.509TyrGln: 0.509 ± 0.614
0.763TyrArg: 0.763 ± 0.254
2.544TyrSer: 2.544 ± 0.411
0.763TyrThr: 0.763 ± 1.02
2.798TyrVal: 2.798 ± 1.54
0.763TyrTrp: 0.763 ± 0.43
1.272TyrTyr: 1.272 ± 0.344
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3932 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski