Amino acid dipepetide frequency for Pythium nunn virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.33AlaAla: 7.33 ± 0.165
1.047AlaCys: 1.047 ± 0.769
3.141AlaAsp: 3.141 ± 0.92
3.141AlaGlu: 3.141 ± 1.854
5.236AlaPhe: 5.236 ± 1.071
7.33AlaGly: 7.33 ± 2.609
1.047AlaHis: 1.047 ± 0.618
5.236AlaIle: 5.236 ± 0.316
2.094AlaLys: 2.094 ± 0.151
8.377AlaLeu: 8.377 ± 3.378
1.047AlaMet: 1.047 ± 0.618
2.094AlaAsn: 2.094 ± 0.151
4.188AlaPro: 4.188 ± 3.076
2.094AlaGln: 2.094 ± 0.151
5.236AlaArg: 5.236 ± 1.071
8.377AlaSer: 8.377 ± 3.378
4.188AlaThr: 4.188 ± 1.689
5.236AlaVal: 5.236 ± 0.316
1.047AlaTrp: 1.047 ± 0.618
7.33AlaTyr: 7.33 ± 2.939
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.047CysGlu: 1.047 ± 0.618
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.094CysIle: 2.094 ± 0.151
1.047CysLys: 1.047 ± 0.618
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.047CysArg: 1.047 ± 0.769
1.047CysSer: 1.047 ± 0.618
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.141AspAla: 3.141 ± 2.307
0.0AspCys: 0.0 ± 0.0
5.236AspAsp: 5.236 ± 0.316
4.188AspGlu: 4.188 ± 0.302
1.047AspPhe: 1.047 ± 0.618
0.0AspGly: 0.0 ± 0.0
1.047AspHis: 1.047 ± 0.618
2.094AspIle: 2.094 ± 0.151
4.188AspLys: 4.188 ± 1.689
6.283AspLeu: 6.283 ± 3.227
0.0AspMet: 0.0 ± 0.551
3.141AspAsn: 3.141 ± 0.467
5.236AspPro: 5.236 ± 0.316
1.047AspGln: 1.047 ± 0.769
1.047AspArg: 1.047 ± 0.618
3.141AspSer: 3.141 ± 1.854
2.094AspThr: 2.094 ± 1.538
7.33AspVal: 7.33 ± 0.165
1.047AspTrp: 1.047 ± 0.618
3.141AspTyr: 3.141 ± 0.92
0.0AspXaa: 0.0 ± 0.0
Glu
8.377GluAla: 8.377 ± 0.783
0.0GluCys: 0.0 ± 0.0
1.047GluAsp: 1.047 ± 0.769
3.141GluGlu: 3.141 ± 1.854
4.188GluPhe: 4.188 ± 1.085
1.047GluGly: 1.047 ± 0.618
1.047GluHis: 1.047 ± 0.618
3.141GluIle: 3.141 ± 0.92
2.094GluLys: 2.094 ± 0.151
3.141GluLeu: 3.141 ± 0.92
1.047GluMet: 1.047 ± 0.769
0.0GluAsn: 0.0 ± 0.0
2.094GluPro: 2.094 ± 1.538
2.094GluGln: 2.094 ± 1.236
5.236GluArg: 5.236 ± 0.316
7.33GluSer: 7.33 ± 0.165
7.33GluThr: 7.33 ± 0.165
9.424GluVal: 9.424 ± 1.401
0.0GluTrp: 0.0 ± 0.0
1.047GluTyr: 1.047 ± 0.618
0.0GluXaa: 0.0 ± 0.0
Phe
3.141PheAla: 3.141 ± 2.307
0.0PheCys: 0.0 ± 0.0
3.141PheAsp: 3.141 ± 1.854
4.188PheGlu: 4.188 ± 1.689
2.094PhePhe: 2.094 ± 1.236
3.141PheGly: 3.141 ± 0.467
1.047PheHis: 1.047 ± 0.769
2.094PheIle: 2.094 ± 1.236
4.188PheLys: 4.188 ± 1.689
4.188PheLeu: 4.188 ± 2.472
1.047PheMet: 1.047 ± 0.769
2.094PheAsn: 2.094 ± 1.538
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
3.141PheArg: 3.141 ± 0.467
4.188PheSer: 4.188 ± 2.472
4.188PheThr: 4.188 ± 1.085
4.188PheVal: 4.188 ± 1.085
1.047PheTrp: 1.047 ± 0.618
1.047PheTyr: 1.047 ± 0.618
0.0PheXaa: 0.0 ± 0.0
Gly
2.094GlyAla: 2.094 ± 1.236
0.0GlyCys: 0.0 ± 0.0
4.188GlyAsp: 4.188 ± 1.085
4.188GlyGlu: 4.188 ± 0.302
4.188GlyPhe: 4.188 ± 0.302
3.141GlyGly: 3.141 ± 1.854
2.094GlyHis: 2.094 ± 1.236
1.047GlyIle: 1.047 ± 0.618
2.094GlyLys: 2.094 ± 1.236
6.283GlyLeu: 6.283 ± 1.84
2.094GlyMet: 2.094 ± 1.236
2.094GlyAsn: 2.094 ± 1.538
1.047GlyPro: 1.047 ± 0.769
1.047GlyGln: 1.047 ± 0.769
3.141GlyArg: 3.141 ± 0.467
3.141GlySer: 3.141 ± 0.467
3.141GlyThr: 3.141 ± 0.92
2.094GlyVal: 2.094 ± 1.236
0.0GlyTrp: 0.0 ± 0.0
3.141GlyTyr: 3.141 ± 0.92
0.0GlyXaa: 0.0 ± 0.0
His
2.094HisAla: 2.094 ± 1.538
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.094HisGlu: 2.094 ± 1.236
1.047HisPhe: 1.047 ± 0.618
3.141HisGly: 3.141 ± 0.467
0.0HisHis: 0.0 ± 0.0
3.141HisIle: 3.141 ± 2.307
0.0HisLys: 0.0 ± 0.0
4.188HisLeu: 4.188 ± 0.302
2.094HisMet: 2.094 ± 0.151
1.047HisAsn: 1.047 ± 0.769
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.047HisArg: 1.047 ± 0.618
2.094HisSer: 2.094 ± 0.151
0.0HisThr: 0.0 ± 0.0
1.047HisVal: 1.047 ± 0.618
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.141IleAla: 3.141 ± 0.467
0.0IleCys: 0.0 ± 0.0
2.094IleAsp: 2.094 ± 1.538
6.283IleGlu: 6.283 ± 3.227
0.0IlePhe: 0.0 ± 0.0
3.141IleGly: 3.141 ± 0.92
2.094IleHis: 2.094 ± 1.538
3.141IleIle: 3.141 ± 0.92
2.094IleLys: 2.094 ± 0.151
2.094IleLeu: 2.094 ± 1.236
2.094IleMet: 2.094 ± 1.236
3.141IleAsn: 3.141 ± 1.854
10.471IlePro: 10.471 ± 0.632
3.141IleGln: 3.141 ± 0.92
1.047IleArg: 1.047 ± 0.618
2.094IleSer: 2.094 ± 1.236
3.141IleThr: 3.141 ± 0.467
1.047IleVal: 1.047 ± 0.618
1.047IleTrp: 1.047 ± 0.618
2.094IleTyr: 2.094 ± 1.538
0.0IleXaa: 0.0 ± 0.0
Lys
11.518LysAla: 11.518 ± 2.911
1.047LysCys: 1.047 ± 0.618
1.047LysAsp: 1.047 ± 0.769
2.094LysGlu: 2.094 ± 0.151
2.094LysPhe: 2.094 ± 1.236
0.0LysGly: 0.0 ± 0.0
1.047LysHis: 1.047 ± 0.769
2.094LysIle: 2.094 ± 0.151
3.141LysLys: 3.141 ± 1.854
8.377LysLeu: 8.377 ± 3.557
1.047LysMet: 1.047 ± 0.769
2.094LysAsn: 2.094 ± 0.151
1.047LysPro: 1.047 ± 0.618
1.047LysGln: 1.047 ± 0.618
4.188LysArg: 4.188 ± 0.302
5.236LysSer: 5.236 ± 1.703
4.188LysThr: 4.188 ± 1.085
3.141LysVal: 3.141 ± 0.92
1.047LysTrp: 1.047 ± 0.618
1.047LysTyr: 1.047 ± 0.618
0.0LysXaa: 0.0 ± 0.0
Leu
3.141LeuAla: 3.141 ± 1.854
1.047LeuCys: 1.047 ± 0.769
5.236LeuAsp: 5.236 ± 1.703
6.283LeuGlu: 6.283 ± 0.453
4.188LeuPhe: 4.188 ± 1.085
8.377LeuGly: 8.377 ± 0.783
0.0LeuHis: 0.0 ± 0.0
5.236LeuIle: 5.236 ± 1.071
6.283LeuLys: 6.283 ± 0.934
2.094LeuLeu: 2.094 ± 1.236
3.141LeuMet: 3.141 ± 0.467
1.047LeuAsn: 1.047 ± 0.769
6.283LeuPro: 6.283 ± 1.84
4.188LeuGln: 4.188 ± 0.302
9.424LeuArg: 9.424 ± 2.788
8.377LeuSer: 8.377 ± 1.991
2.094LeuThr: 2.094 ± 0.151
4.188LeuVal: 4.188 ± 1.689
1.047LeuTrp: 1.047 ± 0.618
4.188LeuTyr: 4.188 ± 1.085
0.0LeuXaa: 0.0 ± 0.0
Met
1.047MetAla: 1.047 ± 0.769
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.047MetGlu: 1.047 ± 0.618
2.094MetPhe: 2.094 ± 0.151
2.094MetGly: 2.094 ± 0.151
0.0MetHis: 0.0 ± 0.0
1.047MetIle: 1.047 ± 0.769
3.141MetLys: 3.141 ± 1.854
2.094MetLeu: 2.094 ± 1.236
0.0MetMet: 0.0 ± 0.0
3.141MetAsn: 3.141 ± 0.467
2.094MetPro: 2.094 ± 0.151
0.0MetGln: 0.0 ± 0.0
2.094MetArg: 2.094 ± 1.538
1.047MetSer: 1.047 ± 0.769
3.141MetThr: 3.141 ± 1.854
1.047MetVal: 1.047 ± 0.618
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.188AsnAla: 4.188 ± 1.085
0.0AsnCys: 0.0 ± 0.0
2.094AsnAsp: 2.094 ± 0.151
2.094AsnGlu: 2.094 ± 1.538
2.094AsnPhe: 2.094 ± 0.151
1.047AsnGly: 1.047 ± 0.769
1.047AsnHis: 1.047 ± 0.769
1.047AsnIle: 1.047 ± 0.618
1.047AsnLys: 1.047 ± 0.769
3.141AsnLeu: 3.141 ± 0.467
2.094AsnMet: 2.094 ± 1.008
0.0AsnAsn: 0.0 ± 0.0
3.141AsnPro: 3.141 ± 2.307
2.094AsnGln: 2.094 ± 1.236
1.047AsnArg: 1.047 ± 0.769
3.141AsnSer: 3.141 ± 0.92
3.141AsnThr: 3.141 ± 0.467
2.094AsnVal: 2.094 ± 1.236
1.047AsnTrp: 1.047 ± 0.618
2.094AsnTyr: 2.094 ± 0.151
0.0AsnXaa: 0.0 ± 0.0
Pro
5.236ProAla: 5.236 ± 2.458
1.047ProCys: 1.047 ± 0.618
4.188ProAsp: 4.188 ± 0.302
2.094ProGlu: 2.094 ± 0.151
4.188ProPhe: 4.188 ± 1.085
2.094ProGly: 2.094 ± 1.236
2.094ProHis: 2.094 ± 1.538
1.047ProIle: 1.047 ± 0.769
4.188ProLys: 4.188 ± 0.302
4.188ProLeu: 4.188 ± 1.689
1.047ProMet: 1.047 ± 0.769
5.236ProAsn: 5.236 ± 1.071
5.236ProPro: 5.236 ± 2.458
3.141ProGln: 3.141 ± 0.467
3.141ProArg: 3.141 ± 2.307
5.236ProSer: 5.236 ± 1.071
2.094ProThr: 2.094 ± 0.151
4.188ProVal: 4.188 ± 0.302
0.0ProTrp: 0.0 ± 0.0
2.094ProTyr: 2.094 ± 1.236
0.0ProXaa: 0.0 ± 0.0
Gln
3.141GlnAla: 3.141 ± 0.467
0.0GlnCys: 0.0 ± 0.0
2.094GlnAsp: 2.094 ± 0.151
3.141GlnGlu: 3.141 ± 1.854
1.047GlnPhe: 1.047 ± 0.769
1.047GlnGly: 1.047 ± 0.769
1.047GlnHis: 1.047 ± 0.618
2.094GlnIle: 2.094 ± 1.236
4.188GlnLys: 4.188 ± 1.085
3.141GlnLeu: 3.141 ± 0.92
1.047GlnMet: 1.047 ± 0.769
1.047GlnAsn: 1.047 ± 0.618
3.141GlnPro: 3.141 ± 2.307
0.0GlnGln: 0.0 ± 0.0
5.236GlnArg: 5.236 ± 1.703
2.094GlnSer: 2.094 ± 0.151
1.047GlnThr: 1.047 ± 0.769
1.047GlnVal: 1.047 ± 0.769
0.0GlnTrp: 0.0 ± 0.0
1.047GlnTyr: 1.047 ± 0.618
0.0GlnXaa: 0.0 ± 0.0
Arg
4.188ArgAla: 4.188 ± 0.302
0.0ArgCys: 0.0 ± 0.0
7.33ArgAsp: 7.33 ± 2.609
2.094ArgGlu: 2.094 ± 1.236
2.094ArgPhe: 2.094 ± 1.538
5.236ArgGly: 5.236 ± 1.703
3.141ArgHis: 3.141 ± 0.92
3.141ArgIle: 3.141 ± 1.854
4.188ArgLys: 4.188 ± 2.472
4.188ArgLeu: 4.188 ± 1.085
2.094ArgMet: 2.094 ± 1.236
1.047ArgAsn: 1.047 ± 0.618
3.141ArgPro: 3.141 ± 0.467
3.141ArgGln: 3.141 ± 0.92
4.188ArgArg: 4.188 ± 1.689
1.047ArgSer: 1.047 ± 0.769
3.141ArgThr: 3.141 ± 2.307
3.141ArgVal: 3.141 ± 1.854
3.141ArgTrp: 3.141 ± 0.92
2.094ArgTyr: 2.094 ± 1.236
0.0ArgXaa: 0.0 ± 0.0
Ser
6.283SerAla: 6.283 ± 0.453
1.047SerCys: 1.047 ± 0.618
4.188SerAsp: 4.188 ± 3.076
2.094SerGlu: 2.094 ± 1.236
5.236SerPhe: 5.236 ± 1.703
3.141SerGly: 3.141 ± 0.467
3.141SerHis: 3.141 ± 0.92
7.33SerIle: 7.33 ± 2.609
3.141SerLys: 3.141 ± 0.92
3.141SerLeu: 3.141 ± 0.467
2.094SerMet: 2.094 ± 0.151
5.236SerAsn: 5.236 ± 0.316
2.094SerPro: 2.094 ± 0.151
6.283SerGln: 6.283 ± 0.453
4.188SerArg: 4.188 ± 1.085
4.188SerSer: 4.188 ± 2.472
3.141SerThr: 3.141 ± 0.92
3.141SerVal: 3.141 ± 0.92
1.047SerTrp: 1.047 ± 0.618
2.094SerTyr: 2.094 ± 0.151
0.0SerXaa: 0.0 ± 0.0
Thr
5.236ThrAla: 5.236 ± 3.845
0.0ThrCys: 0.0 ± 0.0
6.283ThrAsp: 6.283 ± 1.84
4.188ThrGlu: 4.188 ± 3.076
2.094ThrPhe: 2.094 ± 0.151
1.047ThrGly: 1.047 ± 0.618
1.047ThrHis: 1.047 ± 0.618
3.141ThrIle: 3.141 ± 0.467
4.188ThrLys: 4.188 ± 2.472
7.33ThrLeu: 7.33 ± 2.939
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
2.094ThrPro: 2.094 ± 1.538
4.188ThrGln: 4.188 ± 1.085
4.188ThrArg: 4.188 ± 1.085
0.0ThrSer: 0.0 ± 0.0
8.377ThrThr: 8.377 ± 3.378
4.188ThrVal: 4.188 ± 1.689
0.0ThrTrp: 0.0 ± 0.0
3.141ThrTyr: 3.141 ± 0.92
0.0ThrXaa: 0.0 ± 0.0
Val
7.33ValAla: 7.33 ± 2.609
0.0ValCys: 0.0 ± 0.0
1.047ValAsp: 1.047 ± 0.618
6.283ValGlu: 6.283 ± 2.321
3.141ValPhe: 3.141 ± 0.92
3.141ValGly: 3.141 ± 0.92
1.047ValHis: 1.047 ± 0.618
1.047ValIle: 1.047 ± 0.618
3.141ValLys: 3.141 ± 0.92
7.33ValLeu: 7.33 ± 0.165
1.047ValMet: 1.047 ± 0.618
2.094ValAsn: 2.094 ± 1.236
4.188ValPro: 4.188 ± 1.085
1.047ValGln: 1.047 ± 0.618
3.141ValArg: 3.141 ± 0.467
3.141ValSer: 3.141 ± 2.307
4.188ValThr: 4.188 ± 0.302
3.141ValVal: 3.141 ± 1.854
1.047ValTrp: 1.047 ± 0.618
5.236ValTyr: 5.236 ± 1.703
0.0ValXaa: 0.0 ± 0.0
Trp
1.047TrpAla: 1.047 ± 0.618
0.0TrpCys: 0.0 ± 0.0
1.047TrpAsp: 1.047 ± 0.618
1.047TrpGlu: 1.047 ± 0.618
0.0TrpPhe: 0.0 ± 0.0
1.047TrpGly: 1.047 ± 0.618
0.0TrpHis: 0.0 ± 0.0
2.094TrpIle: 2.094 ± 0.151
1.047TrpLys: 1.047 ± 0.618
2.094TrpLeu: 2.094 ± 0.151
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.094TrpSer: 2.094 ± 1.236
0.0TrpThr: 0.0 ± 0.0
1.047TrpVal: 1.047 ± 0.618
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.141TyrAla: 3.141 ± 1.854
1.047TyrCys: 1.047 ± 0.618
2.094TyrAsp: 2.094 ± 0.151
2.094TyrGlu: 2.094 ± 1.236
2.094TyrPhe: 2.094 ± 1.236
1.047TyrGly: 1.047 ± 0.618
1.047TyrHis: 1.047 ± 0.618
2.094TyrIle: 2.094 ± 1.236
1.047TyrLys: 1.047 ± 0.769
4.188TyrLeu: 4.188 ± 1.085
1.047TyrMet: 1.047 ± 0.618
3.141TyrAsn: 3.141 ± 0.92
6.283TyrPro: 6.283 ± 2.321
2.094TyrGln: 2.094 ± 0.151
0.0TyrArg: 0.0 ± 0.0
5.236TyrSer: 5.236 ± 2.458
2.094TyrThr: 2.094 ± 0.151
1.047TyrVal: 1.047 ± 0.769
0.0TyrTrp: 0.0 ± 0.0
3.141TyrTyr: 3.141 ± 0.92
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (956 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski