Amino acid dipepetide frequency for Beihai narna-like virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.826AlaAla: 7.826 ± 7.632
1.739AlaCys: 1.739 ± 0.956
6.957AlaAsp: 6.957 ± 2.143
2.609AlaGlu: 2.609 ± 1.434
0.87AlaPhe: 0.87 ± 1.014
4.348AlaGly: 4.348 ± 2.085
1.739AlaHis: 1.739 ± 2.027
1.739AlaIle: 1.739 ± 0.536
4.348AlaLys: 4.348 ± 0.898
5.217AlaLeu: 5.217 ± 1.376
0.87AlaMet: 0.87 ± 1.014
2.609AlaAsn: 2.609 ± 3.041
4.348AlaPro: 4.348 ± 0.593
1.739AlaGln: 1.739 ± 2.027
0.87AlaArg: 0.87 ± 1.014
6.087AlaSer: 6.087 ± 1.129
3.478AlaThr: 3.478 ± 0.42
4.348AlaVal: 4.348 ± 2.085
2.609AlaTrp: 2.609 ± 0.058
2.609AlaTyr: 2.609 ± 1.549
0.0AlaXaa: 0.0 ± 0.0
Cys
1.739CysAla: 1.739 ± 0.956
0.87CysCys: 0.87 ± 0.478
1.739CysAsp: 1.739 ± 0.956
0.87CysGlu: 0.87 ± 0.478
0.87CysPhe: 0.87 ± 1.014
0.87CysGly: 0.87 ± 1.014
0.0CysHis: 0.0 ± 0.0
0.87CysIle: 0.87 ± 0.478
0.87CysLys: 0.87 ± 0.478
1.739CysLeu: 1.739 ± 0.956
1.739CysMet: 1.739 ± 0.536
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.87CysGln: 0.87 ± 0.478
1.739CysArg: 1.739 ± 0.956
0.87CysSer: 0.87 ± 0.478
2.609CysThr: 2.609 ± 0.058
1.739CysVal: 1.739 ± 0.536
0.0CysTrp: 0.0 ± 0.0
0.87CysTyr: 0.87 ± 0.478
0.0CysXaa: 0.0 ± 0.0
Asp
2.609AspAla: 2.609 ± 1.434
0.0AspCys: 0.0 ± 0.0
2.609AspAsp: 2.609 ± 1.434
3.478AspGlu: 3.478 ± 0.42
6.957AspPhe: 6.957 ± 2.143
3.478AspGly: 3.478 ± 1.912
0.87AspHis: 0.87 ± 0.478
2.609AspIle: 2.609 ± 0.058
3.478AspLys: 3.478 ± 0.42
6.957AspLeu: 6.957 ± 2.332
0.87AspMet: 0.87 ± 0.478
0.0AspAsn: 0.0 ± 0.0
0.0AspPro: 0.0 ± 0.0
1.739AspGln: 1.739 ± 0.536
4.348AspArg: 4.348 ± 0.898
0.87AspSer: 0.87 ± 1.014
2.609AspThr: 2.609 ± 1.549
2.609AspVal: 2.609 ± 0.058
0.87AspTrp: 0.87 ± 1.014
3.478AspTyr: 3.478 ± 1.912
0.0AspXaa: 0.0 ± 0.0
Glu
2.609GluAla: 2.609 ± 1.434
2.609GluCys: 2.609 ± 1.434
2.609GluAsp: 2.609 ± 0.058
3.478GluGlu: 3.478 ± 1.912
1.739GluPhe: 1.739 ± 0.536
2.609GluGly: 2.609 ± 1.434
0.87GluHis: 0.87 ± 0.478
0.87GluIle: 0.87 ± 0.478
0.87GluLys: 0.87 ± 1.014
4.348GluLeu: 4.348 ± 2.39
0.0GluMet: 0.0 ± 0.0
0.87GluAsn: 0.87 ± 0.478
5.217GluPro: 5.217 ± 1.376
1.739GluGln: 1.739 ± 0.956
4.348GluArg: 4.348 ± 0.593
3.478GluSer: 3.478 ± 1.071
3.478GluThr: 3.478 ± 1.071
6.087GluVal: 6.087 ± 1.854
0.0GluTrp: 0.0 ± 0.0
5.217GluTyr: 5.217 ± 0.115
0.0GluXaa: 0.0 ± 0.0
Phe
2.609PheAla: 2.609 ± 0.058
1.739PheCys: 1.739 ± 0.956
5.217PheAsp: 5.217 ± 1.607
1.739PheGlu: 1.739 ± 0.536
1.739PhePhe: 1.739 ± 0.536
1.739PheGly: 1.739 ± 0.956
0.0PheHis: 0.0 ± 0.0
1.739PheIle: 1.739 ± 0.956
0.0PheLys: 0.0 ± 0.0
0.87PheLeu: 0.87 ± 1.014
0.0PheMet: 0.0 ± 0.0
1.739PheAsn: 1.739 ± 0.956
4.348PhePro: 4.348 ± 0.593
3.478PheGln: 3.478 ± 1.071
0.87PheArg: 0.87 ± 0.478
2.609PheSer: 2.609 ± 1.549
5.217PheThr: 5.217 ± 3.099
1.739PheVal: 1.739 ± 0.956
0.87PheTrp: 0.87 ± 0.478
0.87PheTyr: 0.87 ± 0.478
0.0PheXaa: 0.0 ± 0.0
Gly
7.826GlyAla: 7.826 ± 7.632
1.739GlyCys: 1.739 ± 0.956
5.217GlyAsp: 5.217 ± 1.376
1.739GlyGlu: 1.739 ± 0.536
2.609GlyPhe: 2.609 ± 0.058
6.087GlyGly: 6.087 ± 1.129
1.739GlyHis: 1.739 ± 0.956
1.739GlyIle: 1.739 ± 2.027
5.217GlyLys: 5.217 ± 1.376
11.304GlyLeu: 11.304 ± 2.736
0.87GlyMet: 0.87 ± 0.478
0.87GlyAsn: 0.87 ± 0.478
3.478GlyPro: 3.478 ± 1.912
3.478GlyGln: 3.478 ± 0.42
8.696GlyArg: 8.696 ± 1.187
3.478GlySer: 3.478 ± 0.42
2.609GlyThr: 2.609 ± 1.549
8.696GlyVal: 8.696 ± 1.187
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.87HisAla: 0.87 ± 0.478
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.739HisGlu: 1.739 ± 0.956
0.87HisPhe: 0.87 ± 0.478
2.609HisGly: 2.609 ± 0.058
0.0HisHis: 0.0 ± 0.0
0.87HisIle: 0.87 ± 0.478
0.87HisLys: 0.87 ± 0.478
4.348HisLeu: 4.348 ± 0.898
0.87HisMet: 0.87 ± 0.478
0.0HisAsn: 0.0 ± 0.0
3.478HisPro: 3.478 ± 1.071
0.0HisGln: 0.0 ± 0.0
0.87HisArg: 0.87 ± 0.478
0.87HisSer: 0.87 ± 0.478
0.87HisThr: 0.87 ± 1.014
0.87HisVal: 0.87 ± 0.478
0.87HisTrp: 0.87 ± 1.014
1.739HisTyr: 1.739 ± 0.956
0.0HisXaa: 0.0 ± 0.0
Ile
1.739IleAla: 1.739 ± 0.536
0.0IleCys: 0.0 ± 0.0
2.609IleAsp: 2.609 ± 1.434
1.739IleGlu: 1.739 ± 0.536
0.87IlePhe: 0.87 ± 0.478
5.217IleGly: 5.217 ± 0.115
1.739IleHis: 1.739 ± 0.956
1.739IleIle: 1.739 ± 0.536
2.609IleLys: 2.609 ± 1.434
5.217IleLeu: 5.217 ± 1.376
0.87IleMet: 0.87 ± 1.014
4.348IleAsn: 4.348 ± 0.898
2.609IlePro: 2.609 ± 1.434
3.478IleGln: 3.478 ± 0.42
1.739IleArg: 1.739 ± 0.956
1.739IleSer: 1.739 ± 0.536
3.478IleThr: 3.478 ± 1.071
0.87IleVal: 0.87 ± 0.478
1.739IleTrp: 1.739 ± 0.956
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.739LysAla: 1.739 ± 0.536
0.0LysCys: 0.0 ± 0.0
2.609LysAsp: 2.609 ± 1.434
2.609LysGlu: 2.609 ± 0.058
3.478LysPhe: 3.478 ± 0.42
4.348LysGly: 4.348 ± 0.898
2.609LysHis: 2.609 ± 1.434
2.609LysIle: 2.609 ± 1.434
2.609LysLys: 2.609 ± 1.434
4.348LysLeu: 4.348 ± 0.593
0.0LysMet: 0.0 ± 0.0
3.478LysAsn: 3.478 ± 1.912
2.609LysPro: 2.609 ± 0.058
1.739LysGln: 1.739 ± 2.027
3.478LysArg: 3.478 ± 1.912
4.348LysSer: 4.348 ± 2.39
3.478LysThr: 3.478 ± 2.563
5.217LysVal: 5.217 ± 0.115
0.87LysTrp: 0.87 ± 0.478
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.217LeuAla: 5.217 ± 1.376
1.739LeuCys: 1.739 ± 0.536
0.87LeuAsp: 0.87 ± 0.478
4.348LeuGlu: 4.348 ± 0.593
0.0LeuPhe: 0.0 ± 0.0
7.826LeuGly: 7.826 ± 1.665
2.609LeuHis: 2.609 ± 1.434
6.087LeuIle: 6.087 ± 0.363
7.826LeuLys: 7.826 ± 1.319
6.087LeuLeu: 6.087 ± 1.854
2.609LeuMet: 2.609 ± 1.549
5.217LeuAsn: 5.217 ± 0.115
5.217LeuPro: 5.217 ± 0.115
5.217LeuGln: 5.217 ± 2.868
6.087LeuArg: 6.087 ± 3.346
10.435LeuSer: 10.435 ± 0.231
6.087LeuThr: 6.087 ± 1.854
2.609LeuVal: 2.609 ± 0.058
2.609LeuTrp: 2.609 ± 1.434
3.478LeuTyr: 3.478 ± 1.912
0.0LeuXaa: 0.0 ± 0.0
Met
2.609MetAla: 2.609 ± 0.058
0.87MetCys: 0.87 ± 0.478
0.87MetAsp: 0.87 ± 0.478
0.87MetGlu: 0.87 ± 0.478
0.0MetPhe: 0.0 ± 0.0
1.739MetGly: 1.739 ± 0.536
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.87MetLys: 0.87 ± 1.014
0.87MetLeu: 0.87 ± 0.478
0.0MetMet: 0.0 ± 0.0
1.739MetAsn: 1.739 ± 0.536
2.609MetPro: 2.609 ± 1.549
0.0MetGln: 0.0 ± 0.0
0.87MetArg: 0.87 ± 0.478
3.478MetSer: 3.478 ± 2.563
0.87MetThr: 0.87 ± 1.014
3.478MetVal: 3.478 ± 1.071
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.609AsnAla: 2.609 ± 1.549
0.87AsnCys: 0.87 ± 0.478
2.609AsnAsp: 2.609 ± 1.549
0.87AsnGlu: 0.87 ± 0.478
1.739AsnPhe: 1.739 ± 0.956
2.609AsnGly: 2.609 ± 0.058
0.87AsnHis: 0.87 ± 0.478
1.739AsnIle: 1.739 ± 0.536
3.478AsnLys: 3.478 ± 0.42
4.348AsnLeu: 4.348 ± 0.898
3.478AsnMet: 3.478 ± 0.42
0.87AsnAsn: 0.87 ± 0.478
3.478AsnPro: 3.478 ± 1.071
1.739AsnGln: 1.739 ± 2.027
3.478AsnArg: 3.478 ± 1.912
4.348AsnSer: 4.348 ± 2.085
1.739AsnThr: 1.739 ± 0.536
0.0AsnVal: 0.0 ± 0.0
0.87AsnTrp: 0.87 ± 0.478
0.87AsnTyr: 0.87 ± 0.478
0.0AsnXaa: 0.0 ± 0.0
Pro
3.478ProAla: 3.478 ± 1.071
3.478ProCys: 3.478 ± 1.071
1.739ProAsp: 1.739 ± 0.536
1.739ProGlu: 1.739 ± 2.027
5.217ProPhe: 5.217 ± 1.607
0.87ProGly: 0.87 ± 0.478
0.0ProHis: 0.0 ± 0.0
4.348ProIle: 4.348 ± 2.39
1.739ProLys: 1.739 ± 0.536
5.217ProLeu: 5.217 ± 1.376
0.87ProMet: 0.87 ± 0.478
1.739ProAsn: 1.739 ± 2.027
2.609ProPro: 2.609 ± 0.058
3.478ProGln: 3.478 ± 1.912
6.087ProArg: 6.087 ± 4.113
8.696ProSer: 8.696 ± 1.187
1.739ProThr: 1.739 ± 0.956
2.609ProVal: 2.609 ± 1.434
0.0ProTrp: 0.0 ± 0.0
5.217ProTyr: 5.217 ± 1.376
0.0ProXaa: 0.0 ± 0.0
Gln
1.739GlnAla: 1.739 ± 0.956
0.0GlnCys: 0.0 ± 0.0
0.87GlnAsp: 0.87 ± 0.478
3.478GlnGlu: 3.478 ± 0.42
0.87GlnPhe: 0.87 ± 1.014
6.087GlnGly: 6.087 ± 0.363
1.739GlnHis: 1.739 ± 2.027
0.87GlnIle: 0.87 ± 0.478
0.87GlnLys: 0.87 ± 0.478
2.609GlnLeu: 2.609 ± 1.434
0.87GlnMet: 0.87 ± 0.478
2.609GlnAsn: 2.609 ± 1.549
1.739GlnPro: 1.739 ± 0.536
0.87GlnGln: 0.87 ± 0.478
3.478GlnArg: 3.478 ± 0.42
3.478GlnSer: 3.478 ± 1.912
1.739GlnThr: 1.739 ± 0.956
2.609GlnVal: 2.609 ± 1.549
0.87GlnTrp: 0.87 ± 0.478
0.87GlnTyr: 0.87 ± 1.014
0.0GlnXaa: 0.0 ± 0.0
Arg
1.739ArgAla: 1.739 ± 0.536
1.739ArgCys: 1.739 ± 0.536
0.0ArgAsp: 0.0 ± 0.0
4.348ArgGlu: 4.348 ± 2.39
4.348ArgPhe: 4.348 ± 0.898
6.087ArgGly: 6.087 ± 0.363
1.739ArgHis: 1.739 ± 0.536
2.609ArgIle: 2.609 ± 0.058
2.609ArgLys: 2.609 ± 0.058
6.087ArgLeu: 6.087 ± 1.854
1.739ArgMet: 1.739 ± 2.027
4.348ArgAsn: 4.348 ± 3.577
4.348ArgPro: 4.348 ± 2.085
2.609ArgGln: 2.609 ± 1.434
9.565ArgArg: 9.565 ± 0.783
6.087ArgSer: 6.087 ± 3.346
2.609ArgThr: 2.609 ± 1.434
5.217ArgVal: 5.217 ± 2.868
0.87ArgTrp: 0.87 ± 1.014
2.609ArgTyr: 2.609 ± 1.434
0.0ArgXaa: 0.0 ± 0.0
Ser
6.957SerAla: 6.957 ± 2.143
0.87SerCys: 0.87 ± 0.478
4.348SerAsp: 4.348 ± 0.898
6.957SerGlu: 6.957 ± 3.824
0.87SerPhe: 0.87 ± 0.478
6.957SerGly: 6.957 ± 3.635
1.739SerHis: 1.739 ± 0.536
4.348SerIle: 4.348 ± 0.593
2.609SerLys: 2.609 ± 0.058
12.174SerLeu: 12.174 ± 3.75
1.739SerMet: 1.739 ± 0.956
3.478SerAsn: 3.478 ± 0.42
3.478SerPro: 3.478 ± 0.42
1.739SerGln: 1.739 ± 0.536
3.478SerArg: 3.478 ± 2.563
6.087SerSer: 6.087 ± 1.854
1.739SerThr: 1.739 ± 2.027
5.217SerVal: 5.217 ± 0.115
0.87SerTrp: 0.87 ± 0.478
4.348SerTyr: 4.348 ± 0.898
0.0SerXaa: 0.0 ± 0.0
Thr
6.957ThrAla: 6.957 ± 3.635
0.0ThrCys: 0.0 ± 0.0
4.348ThrAsp: 4.348 ± 0.898
1.739ThrGlu: 1.739 ± 0.536
1.739ThrPhe: 1.739 ± 0.536
7.826ThrGly: 7.826 ± 3.157
1.739ThrHis: 1.739 ± 0.956
1.739ThrIle: 1.739 ± 0.956
5.217ThrLys: 5.217 ± 0.115
2.609ThrLeu: 2.609 ± 0.058
1.739ThrMet: 1.739 ± 2.027
2.609ThrAsn: 2.609 ± 1.434
2.609ThrPro: 2.609 ± 1.549
1.739ThrGln: 1.739 ± 0.536
1.739ThrArg: 1.739 ± 0.956
3.478ThrSer: 3.478 ± 4.055
1.739ThrThr: 1.739 ± 2.027
0.0ThrVal: 0.0 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
4.348ThrTyr: 4.348 ± 0.593
0.0ThrXaa: 0.0 ± 0.0
Val
2.609ValAla: 2.609 ± 3.041
1.739ValCys: 1.739 ± 0.536
1.739ValAsp: 1.739 ± 0.956
4.348ValGlu: 4.348 ± 0.898
0.0ValPhe: 0.0 ± 0.0
5.217ValGly: 5.217 ± 1.607
2.609ValHis: 2.609 ± 1.434
6.957ValIle: 6.957 ± 2.332
3.478ValLys: 3.478 ± 1.912
3.478ValLeu: 3.478 ± 1.912
0.0ValMet: 0.0 ± 0.587
0.87ValAsn: 0.87 ± 0.478
5.217ValPro: 5.217 ± 0.115
1.739ValGln: 1.739 ± 0.956
6.087ValArg: 6.087 ± 0.363
4.348ValSer: 4.348 ± 2.085
5.217ValThr: 5.217 ± 1.607
2.609ValVal: 2.609 ± 0.058
0.87ValTrp: 0.87 ± 1.014
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.87TrpAsp: 0.87 ± 0.478
1.739TrpGlu: 1.739 ± 0.536
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.739TrpLys: 1.739 ± 0.536
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
3.478TrpAsn: 3.478 ± 0.42
0.87TrpPro: 0.87 ± 0.478
0.87TrpGln: 0.87 ± 0.478
0.87TrpArg: 0.87 ± 0.478
2.609TrpSer: 2.609 ± 1.434
0.87TrpThr: 0.87 ± 1.014
1.739TrpVal: 1.739 ± 0.536
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.478TyrAla: 3.478 ± 1.071
0.87TyrCys: 0.87 ± 0.478
2.609TyrAsp: 2.609 ± 0.058
2.609TyrGlu: 2.609 ± 1.434
4.348TyrPhe: 4.348 ± 0.898
0.87TyrGly: 0.87 ± 1.014
0.0TyrHis: 0.0 ± 0.0
0.87TyrIle: 0.87 ± 0.478
0.87TyrLys: 0.87 ± 0.478
4.348TyrLeu: 4.348 ± 2.39
1.739TyrMet: 1.739 ± 0.839
1.739TyrAsn: 1.739 ± 0.956
2.609TyrPro: 2.609 ± 0.058
0.0TyrGln: 0.0 ± 0.0
2.609TyrArg: 2.609 ± 1.434
2.609TyrSer: 2.609 ± 0.058
1.739TyrThr: 1.739 ± 0.956
1.739TyrVal: 1.739 ± 0.536
0.87TyrTrp: 0.87 ± 0.478
0.87TyrTyr: 0.87 ± 0.478
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1151 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski