Amino acid dipepetide frequency for Xanthomonas phage Carpasina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.995AlaAla: 12.995 ± 1.05
1.0AlaCys: 1.0 ± 0.245
6.577AlaAsp: 6.577 ± 0.571
5.787AlaGlu: 5.787 ± 0.728
4.156AlaPhe: 4.156 ± 0.47
7.787AlaGly: 7.787 ± 1.029
1.578AlaHis: 1.578 ± 0.299
5.893AlaIle: 5.893 ± 0.563
5.682AlaLys: 5.682 ± 0.725
8.576AlaLeu: 8.576 ± 0.666
2.473AlaMet: 2.473 ± 0.333
3.578AlaAsn: 3.578 ± 0.658
4.998AlaPro: 4.998 ± 0.582
4.104AlaGln: 4.104 ± 0.554
5.209AlaArg: 5.209 ± 0.523
7.313AlaSer: 7.313 ± 0.622
5.524AlaThr: 5.524 ± 0.696
5.893AlaVal: 5.893 ± 0.73
1.21AlaTrp: 1.21 ± 0.242
2.052AlaTyr: 2.052 ± 0.302
0.0AlaXaa: 0.0 ± 0.0
Cys
1.315CysAla: 1.315 ± 0.252
0.053CysCys: 0.053 ± 0.051
0.368CysAsp: 0.368 ± 0.153
0.631CysGlu: 0.631 ± 0.152
0.421CysPhe: 0.421 ± 0.135
0.789CysGly: 0.789 ± 0.184
0.263CysHis: 0.263 ± 0.12
0.421CysIle: 0.421 ± 0.149
0.368CysLys: 0.368 ± 0.138
0.631CysLeu: 0.631 ± 0.182
0.21CysMet: 0.21 ± 0.098
0.158CysAsn: 0.158 ± 0.1
0.684CysPro: 0.684 ± 0.193
0.368CysGln: 0.368 ± 0.144
0.368CysArg: 0.368 ± 0.149
0.316CysSer: 0.316 ± 0.118
0.737CysThr: 0.737 ± 0.166
0.789CysVal: 0.789 ± 0.183
0.053CysTrp: 0.053 ± 0.054
0.263CysTyr: 0.263 ± 0.099
0.0CysXaa: 0.0 ± 0.0
Asp
5.787AspAla: 5.787 ± 0.684
0.526AspCys: 0.526 ± 0.14
2.946AspAsp: 2.946 ± 0.477
3.788AspGlu: 3.788 ± 0.524
2.999AspPhe: 2.999 ± 0.416
5.524AspGly: 5.524 ± 0.448
1.0AspHis: 1.0 ± 0.276
4.156AspIle: 4.156 ± 0.556
3.209AspLys: 3.209 ± 0.464
3.946AspLeu: 3.946 ± 0.571
1.473AspMet: 1.473 ± 0.286
2.42AspAsn: 2.42 ± 0.348
2.999AspPro: 2.999 ± 0.403
1.999AspGln: 1.999 ± 0.323
3.262AspArg: 3.262 ± 0.466
3.104AspSer: 3.104 ± 0.43
3.209AspThr: 3.209 ± 0.385
3.946AspVal: 3.946 ± 0.489
0.842AspTrp: 0.842 ± 0.171
1.841AspTyr: 1.841 ± 0.265
0.0AspXaa: 0.0 ± 0.0
Glu
7.471GluAla: 7.471 ± 0.905
0.631GluCys: 0.631 ± 0.198
3.578GluAsp: 3.578 ± 0.533
5.261GluGlu: 5.261 ± 0.738
3.104GluPhe: 3.104 ± 0.439
4.367GluGly: 4.367 ± 0.61
1.052GluHis: 1.052 ± 0.223
3.104GluIle: 3.104 ± 0.416
3.315GluLys: 3.315 ± 0.505
5.682GluLeu: 5.682 ± 0.496
2.21GluMet: 2.21 ± 0.332
2.683GluAsn: 2.683 ± 0.348
1.631GluPro: 1.631 ± 0.297
3.157GluGln: 3.157 ± 0.448
3.841GluArg: 3.841 ± 0.545
4.735GluSer: 4.735 ± 0.543
2.473GluThr: 2.473 ± 0.37
3.735GluVal: 3.735 ± 0.422
0.842GluTrp: 0.842 ± 0.189
2.104GluTyr: 2.104 ± 0.326
0.0GluXaa: 0.0 ± 0.0
Phe
2.631PheAla: 2.631 ± 0.367
0.21PheCys: 0.21 ± 0.089
3.472PheAsp: 3.472 ± 0.515
2.736PheGlu: 2.736 ± 0.405
0.947PhePhe: 0.947 ± 0.204
3.525PheGly: 3.525 ± 0.476
0.368PheHis: 0.368 ± 0.13
3.104PheIle: 3.104 ± 0.334
2.683PheLys: 2.683 ± 0.334
2.157PheLeu: 2.157 ± 0.391
0.737PheMet: 0.737 ± 0.181
2.736PheAsn: 2.736 ± 0.405
1.052PhePro: 1.052 ± 0.272
1.684PheGln: 1.684 ± 0.277
1.894PheArg: 1.894 ± 0.339
2.42PheSer: 2.42 ± 0.453
2.631PheThr: 2.631 ± 0.405
2.578PheVal: 2.578 ± 0.349
0.789PheTrp: 0.789 ± 0.217
1.315PheTyr: 1.315 ± 0.213
0.0PheXaa: 0.0 ± 0.0
Gly
7.734GlyAla: 7.734 ± 1.317
1.0GlyCys: 1.0 ± 0.2
3.999GlyAsp: 3.999 ± 0.466
4.788GlyGlu: 4.788 ± 0.639
3.472GlyPhe: 3.472 ± 0.53
6.156GlyGly: 6.156 ± 1.859
1.631GlyHis: 1.631 ± 0.29
4.682GlyIle: 4.682 ± 0.519
4.209GlyLys: 4.209 ± 0.714
5.577GlyLeu: 5.577 ± 0.6
1.894GlyMet: 1.894 ± 0.236
2.788GlyAsn: 2.788 ± 0.45
1.999GlyPro: 1.999 ± 0.361
2.736GlyGln: 2.736 ± 0.459
3.893GlyArg: 3.893 ± 0.467
4.63GlySer: 4.63 ± 0.538
4.051GlyThr: 4.051 ± 0.639
6.997GlyVal: 6.997 ± 0.661
1.473GlyTrp: 1.473 ± 0.233
1.631GlyTyr: 1.631 ± 0.284
0.0GlyXaa: 0.0 ± 0.0
His
1.526HisAla: 1.526 ± 0.335
0.21HisCys: 0.21 ± 0.108
0.684HisAsp: 0.684 ± 0.234
1.0HisGlu: 1.0 ± 0.193
0.737HisPhe: 0.737 ± 0.174
1.368HisGly: 1.368 ± 0.312
0.421HisHis: 0.421 ± 0.16
1.052HisIle: 1.052 ± 0.222
0.684HisLys: 0.684 ± 0.21
1.21HisLeu: 1.21 ± 0.204
0.263HisMet: 0.263 ± 0.132
0.789HisAsn: 0.789 ± 0.181
0.631HisPro: 0.631 ± 0.207
0.737HisGln: 0.737 ± 0.238
1.0HisArg: 1.0 ± 0.227
1.052HisSer: 1.052 ± 0.219
0.737HisThr: 0.737 ± 0.185
0.947HisVal: 0.947 ± 0.253
0.21HisTrp: 0.21 ± 0.112
0.368HisTyr: 0.368 ± 0.138
0.0HisXaa: 0.0 ± 0.0
Ile
5.893IleAla: 5.893 ± 0.562
0.579IleCys: 0.579 ± 0.163
4.998IleAsp: 4.998 ± 0.617
4.525IleGlu: 4.525 ± 0.506
1.578IlePhe: 1.578 ± 0.297
3.157IleGly: 3.157 ± 0.433
0.737IleHis: 0.737 ± 0.205
3.052IleIle: 3.052 ± 0.403
4.472IleLys: 4.472 ± 0.681
4.472IleLeu: 4.472 ± 0.487
1.631IleMet: 1.631 ± 0.3
3.209IleAsn: 3.209 ± 0.38
2.683IlePro: 2.683 ± 0.357
2.473IleGln: 2.473 ± 0.28
2.736IleArg: 2.736 ± 0.32
4.156IleSer: 4.156 ± 0.546
3.946IleThr: 3.946 ± 0.522
4.577IleVal: 4.577 ± 0.614
0.526IleTrp: 0.526 ± 0.171
0.947IleTyr: 0.947 ± 0.2
0.0IleXaa: 0.0 ± 0.0
Lys
6.419LysAla: 6.419 ± 0.825
0.421LysCys: 0.421 ± 0.169
4.051LysAsp: 4.051 ± 0.398
3.42LysGlu: 3.42 ± 0.528
2.525LysPhe: 2.525 ± 0.34
3.367LysGly: 3.367 ± 0.498
1.105LysHis: 1.105 ± 0.269
3.525LysIle: 3.525 ± 0.578
4.209LysLys: 4.209 ± 0.693
3.735LysLeu: 3.735 ± 0.444
1.894LysMet: 1.894 ± 0.39
2.368LysAsn: 2.368 ± 0.31
2.525LysPro: 2.525 ± 0.388
1.841LysGln: 1.841 ± 0.264
3.315LysArg: 3.315 ± 0.453
3.735LysSer: 3.735 ± 0.435
3.42LysThr: 3.42 ± 0.433
4.104LysVal: 4.104 ± 0.411
0.842LysTrp: 0.842 ± 0.206
1.894LysTyr: 1.894 ± 0.377
0.0LysXaa: 0.0 ± 0.0
Leu
7.05LeuAla: 7.05 ± 0.689
0.894LeuCys: 0.894 ± 0.19
3.63LeuAsp: 3.63 ± 0.497
4.735LeuGlu: 4.735 ± 0.545
2.315LeuPhe: 2.315 ± 0.326
5.524LeuGly: 5.524 ± 0.54
1.052LeuHis: 1.052 ± 0.23
4.367LeuIle: 4.367 ± 0.458
3.946LeuLys: 3.946 ± 0.374
5.63LeuLeu: 5.63 ± 0.613
1.684LeuMet: 1.684 ± 0.26
3.946LeuAsn: 3.946 ± 0.432
3.262LeuPro: 3.262 ± 0.478
1.841LeuGln: 1.841 ± 0.295
4.788LeuArg: 4.788 ± 0.522
7.471LeuSer: 7.471 ± 0.517
4.788LeuThr: 4.788 ± 0.446
4.735LeuVal: 4.735 ± 0.513
0.631LeuTrp: 0.631 ± 0.151
1.947LeuTyr: 1.947 ± 0.3
0.0LeuXaa: 0.0 ± 0.0
Met
2.21MetAla: 2.21 ± 0.309
0.21MetCys: 0.21 ± 0.098
1.684MetAsp: 1.684 ± 0.277
1.736MetGlu: 1.736 ± 0.286
1.052MetPhe: 1.052 ± 0.205
1.736MetGly: 1.736 ± 0.393
0.368MetHis: 0.368 ± 0.133
1.052MetIle: 1.052 ± 0.237
1.894MetLys: 1.894 ± 0.263
2.104MetLeu: 2.104 ± 0.295
0.737MetMet: 0.737 ± 0.228
1.052MetAsn: 1.052 ± 0.196
1.473MetPro: 1.473 ± 0.307
1.21MetGln: 1.21 ± 0.278
1.999MetArg: 1.999 ± 0.324
2.42MetSer: 2.42 ± 0.369
1.631MetThr: 1.631 ± 0.283
1.473MetVal: 1.473 ± 0.284
0.421MetTrp: 0.421 ± 0.141
0.526MetTyr: 0.526 ± 0.149
0.0MetXaa: 0.0 ± 0.0
Asn
4.788AsnAla: 4.788 ± 0.428
0.263AsnCys: 0.263 ± 0.128
1.684AsnAsp: 1.684 ± 0.263
2.894AsnGlu: 2.894 ± 0.381
1.684AsnPhe: 1.684 ± 0.298
4.104AsnGly: 4.104 ± 0.549
0.737AsnHis: 0.737 ± 0.177
2.368AsnIle: 2.368 ± 0.374
2.21AsnLys: 2.21 ± 0.318
3.525AsnLeu: 3.525 ± 0.371
1.157AsnMet: 1.157 ± 0.258
1.421AsnAsn: 1.421 ± 0.384
3.157AsnPro: 3.157 ± 0.552
2.104AsnGln: 2.104 ± 0.419
2.42AsnArg: 2.42 ± 0.357
2.683AsnSer: 2.683 ± 0.569
2.315AsnThr: 2.315 ± 0.357
2.841AsnVal: 2.841 ± 0.406
1.0AsnTrp: 1.0 ± 0.253
1.263AsnTyr: 1.263 ± 0.289
0.0AsnXaa: 0.0 ± 0.0
Pro
4.788ProAla: 4.788 ± 0.561
0.474ProCys: 0.474 ± 0.155
3.157ProAsp: 3.157 ± 0.49
3.104ProGlu: 3.104 ± 0.46
1.473ProPhe: 1.473 ± 0.293
3.472ProGly: 3.472 ± 0.528
0.579ProHis: 0.579 ± 0.174
2.42ProIle: 2.42 ± 0.296
2.683ProLys: 2.683 ± 0.42
2.841ProLeu: 2.841 ± 0.422
1.105ProMet: 1.105 ± 0.233
2.788ProAsn: 2.788 ± 0.518
1.421ProPro: 1.421 ± 0.318
1.894ProGln: 1.894 ± 0.29
1.421ProArg: 1.421 ± 0.259
2.946ProSer: 2.946 ± 0.431
1.841ProThr: 1.841 ± 0.337
2.368ProVal: 2.368 ± 0.33
0.421ProTrp: 0.421 ± 0.162
1.21ProTyr: 1.21 ± 0.236
0.0ProXaa: 0.0 ± 0.0
Gln
3.578GlnAla: 3.578 ± 0.409
0.368GlnCys: 0.368 ± 0.129
1.578GlnAsp: 1.578 ± 0.288
2.052GlnGlu: 2.052 ± 0.341
2.052GlnPhe: 2.052 ± 0.334
2.894GlnGly: 2.894 ± 0.469
0.421GlnHis: 0.421 ± 0.139
3.052GlnIle: 3.052 ± 0.362
2.42GlnLys: 2.42 ± 0.299
3.472GlnLeu: 3.472 ± 0.338
1.263GlnMet: 1.263 ± 0.249
2.104GlnAsn: 2.104 ± 0.387
1.473GlnPro: 1.473 ± 0.361
1.631GlnGln: 1.631 ± 0.35
1.789GlnArg: 1.789 ± 0.298
3.157GlnSer: 3.157 ± 0.388
1.894GlnThr: 1.894 ± 0.326
3.209GlnVal: 3.209 ± 0.321
0.316GlnTrp: 0.316 ± 0.141
0.947GlnTyr: 0.947 ± 0.206
0.0GlnXaa: 0.0 ± 0.0
Arg
4.209ArgAla: 4.209 ± 0.399
0.579ArgCys: 0.579 ± 0.161
3.42ArgAsp: 3.42 ± 0.394
3.42ArgGlu: 3.42 ± 0.531
2.262ArgPhe: 2.262 ± 0.372
3.367ArgGly: 3.367 ± 0.389
0.737ArgHis: 0.737 ± 0.197
3.525ArgIle: 3.525 ± 0.383
2.999ArgLys: 2.999 ± 0.496
4.104ArgLeu: 4.104 ± 0.448
1.578ArgMet: 1.578 ± 0.243
3.157ArgAsn: 3.157 ± 0.388
2.104ArgPro: 2.104 ± 0.376
2.473ArgGln: 2.473 ± 0.41
2.946ArgArg: 2.946 ± 0.524
3.42ArgSer: 3.42 ± 0.478
2.052ArgThr: 2.052 ± 0.322
4.209ArgVal: 4.209 ± 0.424
0.421ArgTrp: 0.421 ± 0.132
2.262ArgTyr: 2.262 ± 0.337
0.0ArgXaa: 0.0 ± 0.0
Ser
6.945SerAla: 6.945 ± 0.881
0.316SerCys: 0.316 ± 0.122
4.104SerAsp: 4.104 ± 0.447
4.84SerGlu: 4.84 ± 0.533
2.525SerPhe: 2.525 ± 0.341
6.05SerGly: 6.05 ± 0.791
1.052SerHis: 1.052 ± 0.27
4.893SerIle: 4.893 ± 0.68
3.946SerLys: 3.946 ± 0.544
4.788SerLeu: 4.788 ± 0.463
1.789SerMet: 1.789 ± 0.302
2.946SerAsn: 2.946 ± 0.375
3.525SerPro: 3.525 ± 0.593
2.473SerGln: 2.473 ± 0.329
3.315SerArg: 3.315 ± 0.433
4.998SerSer: 4.998 ± 0.525
4.051SerThr: 4.051 ± 0.439
5.472SerVal: 5.472 ± 0.487
0.789SerTrp: 0.789 ± 0.211
1.894SerTyr: 1.894 ± 0.333
0.0SerXaa: 0.0 ± 0.0
Thr
6.471ThrAla: 6.471 ± 0.621
0.368ThrCys: 0.368 ± 0.12
2.525ThrAsp: 2.525 ± 0.374
2.473ThrGlu: 2.473 ± 0.378
2.631ThrPhe: 2.631 ± 0.324
4.472ThrGly: 4.472 ± 0.431
0.789ThrHis: 0.789 ± 0.244
3.472ThrIle: 3.472 ± 0.441
3.578ThrLys: 3.578 ± 0.449
4.051ThrLeu: 4.051 ± 0.554
1.157ThrMet: 1.157 ± 0.246
1.473ThrAsn: 1.473 ± 0.31
2.788ThrPro: 2.788 ± 0.379
1.999ThrGln: 1.999 ± 0.332
2.946ThrArg: 2.946 ± 0.395
4.946ThrSer: 4.946 ± 0.497
3.104ThrThr: 3.104 ± 0.454
3.42ThrVal: 3.42 ± 0.514
0.789ThrTrp: 0.789 ± 0.197
1.473ThrTyr: 1.473 ± 0.244
0.0ThrXaa: 0.0 ± 0.0
Val
6.577ValAla: 6.577 ± 0.696
0.789ValCys: 0.789 ± 0.219
4.63ValAsp: 4.63 ± 0.517
5.209ValGlu: 5.209 ± 0.492
2.578ValPhe: 2.578 ± 0.342
4.472ValGly: 4.472 ± 0.572
1.052ValHis: 1.052 ± 0.244
4.104ValIle: 4.104 ± 0.453
4.472ValLys: 4.472 ± 0.387
4.63ValLeu: 4.63 ± 0.389
2.42ValMet: 2.42 ± 0.323
2.946ValAsn: 2.946 ± 0.474
2.578ValPro: 2.578 ± 0.314
2.894ValGln: 2.894 ± 0.419
3.735ValArg: 3.735 ± 0.591
4.998ValSer: 4.998 ± 0.566
4.262ValThr: 4.262 ± 0.538
4.367ValVal: 4.367 ± 0.542
0.684ValTrp: 0.684 ± 0.169
1.473ValTyr: 1.473 ± 0.354
0.0ValXaa: 0.0 ± 0.0
Trp
1.368TrpAla: 1.368 ± 0.262
0.105TrpCys: 0.105 ± 0.078
0.789TrpAsp: 0.789 ± 0.216
0.947TrpGlu: 0.947 ± 0.245
0.368TrpPhe: 0.368 ± 0.128
0.684TrpGly: 0.684 ± 0.181
0.316TrpHis: 0.316 ± 0.153
0.789TrpIle: 0.789 ± 0.223
0.631TrpLys: 0.631 ± 0.191
1.052TrpLeu: 1.052 ± 0.235
0.421TrpMet: 0.421 ± 0.12
0.526TrpAsn: 0.526 ± 0.14
0.421TrpPro: 0.421 ± 0.149
0.579TrpGln: 0.579 ± 0.207
1.0TrpArg: 1.0 ± 0.254
0.631TrpSer: 0.631 ± 0.187
0.684TrpThr: 0.684 ± 0.228
0.789TrpVal: 0.789 ± 0.211
0.105TrpTrp: 0.105 ± 0.072
0.474TrpTyr: 0.474 ± 0.139
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.631TyrAla: 2.631 ± 0.366
0.21TyrCys: 0.21 ± 0.112
1.105TyrAsp: 1.105 ± 0.221
1.631TyrGlu: 1.631 ± 0.291
0.789TyrPhe: 0.789 ± 0.2
2.525TyrGly: 2.525 ± 0.316
0.368TyrHis: 0.368 ± 0.13
1.315TyrIle: 1.315 ± 0.303
1.105TyrLys: 1.105 ± 0.191
2.052TyrLeu: 2.052 ± 0.286
0.842TyrMet: 0.842 ± 0.218
1.526TyrAsn: 1.526 ± 0.22
1.0TyrPro: 1.0 ± 0.197
1.473TyrGln: 1.473 ± 0.319
1.368TyrArg: 1.368 ± 0.237
1.578TyrSer: 1.578 ± 0.243
1.578TyrThr: 1.578 ± 0.291
2.42TyrVal: 2.42 ± 0.44
0.316TyrTrp: 0.316 ± 0.115
0.579TyrTyr: 0.579 ± 0.188
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 86 proteins (19008 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski