Amino acid dipepetide frequency for Batrachochytrium salamandrivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.824AlaAla: 7.824 ± 0.068	1.002AlaCys: 1.002 ± 0.014	3.948AlaAsp: 3.948 ± 0.027	3.671AlaGlu: 3.671 ± 0.026	2.584AlaPhe: 2.584 ± 0.022	4.14AlaGly: 4.14 ± 0.035	1.904AlaHis: 1.904 ± 0.019	4.505AlaIle: 4.505 ± 0.031	3.518AlaLys: 3.518 ± 0.03	7.117AlaLeu: 7.117 ± 0.049	1.928AlaMet: 1.928 ± 0.021	2.823AlaAsn: 2.823 ± 0.026	3.584AlaPro: 3.584 ± 0.033	2.802AlaGln: 2.802 ± 0.026	3.503AlaArg: 3.503 ± 0.026	7.905AlaSer: 7.905 ± 0.05	5.437AlaThr: 5.437 ± 0.042	5.026AlaVal: 5.026 ± 0.033	0.702AlaTrp: 0.702 ± 0.011	1.842AlaTyr: 1.842 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.898CysAla: 0.898 ± 0.013	0.295CysCys: 0.295 ± 0.009	0.783CysAsp: 0.783 ± 0.012	0.662CysGlu: 0.662 ± 0.012	0.571CysPhe: 0.571 ± 0.01	0.913CysGly: 0.913 ± 0.016	0.396CysHis: 0.396 ± 0.009	1.019CysIle: 1.019 ± 0.013	0.662CysLys: 0.662 ± 0.012	1.333CysLeu: 1.333 ± 0.018	0.386CysMet: 0.386 ± 0.009	0.548CysAsn: 0.548 ± 0.01	0.692CysPro: 0.692 ± 0.012	0.534CysGln: 0.534 ± 0.01	0.732CysArg: 0.732 ± 0.012	1.3CysSer: 1.3 ± 0.017	0.885CysThr: 0.885 ± 0.012	0.878CysVal: 0.878 ± 0.014	0.158CysTrp: 0.158 ± 0.005	0.378CysTyr: 0.378 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.503AspAla: 4.503 ± 0.029	0.724AspCys: 0.724 ± 0.015	4.114AspAsp: 4.114 ± 0.049	3.511AspGlu: 3.511 ± 0.038	1.955AspPhe: 1.955 ± 0.02	3.431AspGly: 3.431 ± 0.032	1.48AspHis: 1.48 ± 0.018	3.763AspIle: 3.763 ± 0.029	2.375AspLys: 2.375 ± 0.023	5.381AspLeu: 5.381 ± 0.036	1.688AspMet: 1.688 ± 0.016	2.018AspAsn: 2.018 ± 0.021	3.148AspPro: 3.148 ± 0.025	2.084AspGln: 2.084 ± 0.022	2.846AspArg: 2.846 ± 0.027	5.287AspSer: 5.287 ± 0.033	3.819AspThr: 3.819 ± 0.031	3.408AspVal: 3.408 ± 0.026	0.585AspTrp: 0.585 ± 0.01	1.526AspTyr: 1.526 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	3.853GluAla: 3.853 ± 0.03	0.748GluCys: 0.748 ± 0.012	3.106GluAsp: 3.106 ± 0.037	3.51GluGlu: 3.51 ± 0.041	1.945GluPhe: 1.945 ± 0.021	2.404GluGly: 2.404 ± 0.024	1.37GluHis: 1.37 ± 0.016	3.185GluIle: 3.185 ± 0.028	3.239GluLys: 3.239 ± 0.037	5.124GluLeu: 5.124 ± 0.042	1.528GluMet: 1.528 ± 0.017	2.196GluAsn: 2.196 ± 0.022	2.083GluPro: 2.083 ± 0.022	2.27GluGln: 2.27 ± 0.024	2.947GluArg: 2.947 ± 0.029	4.919GluSer: 4.919 ± 0.038	3.181GluThr: 3.181 ± 0.028	2.754GluVal: 2.754 ± 0.023	0.577GluTrp: 0.577 ± 0.011	1.671GluTyr: 1.671 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.216PheAla: 2.216 ± 0.021	0.543PheCys: 0.543 ± 0.01	2.209PheAsp: 2.209 ± 0.021	2.061PheGlu: 2.061 ± 0.022	1.449PhePhe: 1.449 ± 0.019	2.511PheGly: 2.511 ± 0.028	0.873PheHis: 0.873 ± 0.013	1.976PheIle: 1.976 ± 0.023	1.816PheLys: 1.816 ± 0.018	3.297PheLeu: 3.297 ± 0.028	0.826PheMet: 0.826 ± 0.012	1.455PheAsn: 1.455 ± 0.017	1.671PhePro: 1.671 ± 0.02	1.499PheGln: 1.499 ± 0.018	1.64PheArg: 1.64 ± 0.018	3.513PheSer: 3.513 ± 0.028	1.984PheThr: 1.984 ± 0.021	2.336PheVal: 2.336 ± 0.024	0.406PheTrp: 0.406 ± 0.009	1.02PheTyr: 1.02 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	3.973GlyAla: 3.973 ± 0.037	0.796GlyCys: 0.796 ± 0.013	3.147GlyAsp: 3.147 ± 0.026	2.561GlyGlu: 2.561 ± 0.026	2.138GlyPhe: 2.138 ± 0.024	4.365GlyGly: 4.365 ± 0.051	1.595GlyHis: 1.595 ± 0.02	3.46GlyIle: 3.46 ± 0.028	2.892GlyLys: 2.892 ± 0.027	5.007GlyLeu: 5.007 ± 0.032	1.553GlyMet: 1.553 ± 0.025	2.433GlyAsn: 2.433 ± 0.022	2.206GlyPro: 2.206 ± 0.027	2.086GlyGln: 2.086 ± 0.022	3.036GlyArg: 3.036 ± 0.03	5.988GlySer: 5.988 ± 0.043	3.375GlyThr: 3.375 ± 0.03	3.797GlyVal: 3.797 ± 0.029	0.662GlyTrp: 0.662 ± 0.012	1.583GlyTyr: 1.583 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	1.95HisAla: 1.95 ± 0.02	0.389HisCys: 0.389 ± 0.01	1.468HisAsp: 1.468 ± 0.017	1.212HisGlu: 1.212 ± 0.018	0.924HisPhe: 0.924 ± 0.013	1.596HisGly: 1.596 ± 0.02	1.193HisHis: 1.193 ± 0.02	1.851HisIle: 1.851 ± 0.019	1.093HisLys: 1.093 ± 0.016	2.711HisLeu: 2.711 ± 0.024	0.71HisMet: 0.71 ± 0.011	1.085HisAsn: 1.085 ± 0.017	1.82HisPro: 1.82 ± 0.023	1.428HisGln: 1.428 ± 0.023	1.636HisArg: 1.636 ± 0.018	2.921HisSer: 2.921 ± 0.027	1.875HisThr: 1.875 ± 0.02	1.558HisVal: 1.558 ± 0.017	0.242HisTrp: 0.242 ± 0.008	0.732HisTyr: 0.732 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.168IleAla: 4.168 ± 0.029	0.974IleCys: 0.974 ± 0.016	3.491IleAsp: 3.491 ± 0.022	3.195IleGlu: 3.195 ± 0.028	1.944IlePhe: 1.944 ± 0.021	3.11IleGly: 3.11 ± 0.025	1.662IleHis: 1.662 ± 0.019	2.989IleIle: 2.989 ± 0.03	3.006IleLys: 3.006 ± 0.029	5.187IleLeu: 5.187 ± 0.031	1.26IleMet: 1.26 ± 0.014	2.305IleAsn: 2.305 ± 0.021	3.388IlePro: 3.388 ± 0.024	2.612IleGln: 2.612 ± 0.023	2.996IleArg: 2.996 ± 0.025	6.004IleSer: 6.004 ± 0.037	3.113IleThr: 3.113 ± 0.025	3.653IleVal: 3.653 ± 0.028	0.647IleTrp: 0.647 ± 0.012	1.685IleTyr: 1.685 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	3.623LysAla: 3.623 ± 0.033	0.643LysCys: 0.643 ± 0.012	2.806LysAsp: 2.806 ± 0.024	3.176LysGlu: 3.176 ± 0.031	1.555LysPhe: 1.555 ± 0.02	2.483LysGly: 2.483 ± 0.023	1.286LysHis: 1.286 ± 0.016	2.696LysIle: 2.696 ± 0.025	3.343LysLys: 3.343 ± 0.04	4.605LysLeu: 4.605 ± 0.04	1.257LysMet: 1.257 ± 0.017	1.968LysAsn: 1.968 ± 0.021	2.503LysPro: 2.503 ± 0.027	2.121LysGln: 2.121 ± 0.024	3.181LysArg: 3.181 ± 0.028	4.49LysSer: 4.49 ± 0.036	3.149LysThr: 3.149 ± 0.024	2.691LysVal: 2.691 ± 0.022	0.535LysTrp: 0.535 ± 0.01	1.489LysTyr: 1.489 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.408LeuAla: 7.408 ± 0.04	1.54LeuCys: 1.54 ± 0.017	5.661LeuAsp: 5.661 ± 0.035	5.536LeuGlu: 5.536 ± 0.044	3.566LeuPhe: 3.566 ± 0.027	5.074LeuGly: 5.074 ± 0.032	2.807LeuHis: 2.807 ± 0.029	4.513LeuIle: 4.513 ± 0.038	4.897LeuLys: 4.897 ± 0.037	9.436LeuLeu: 9.436 ± 0.067	1.998LeuMet: 1.998 ± 0.021	3.526LeuAsn: 3.526 ± 0.029	5.369LeuPro: 5.369 ± 0.039	4.593LeuGln: 4.593 ± 0.044	4.89LeuArg: 4.89 ± 0.03	9.186LeuSer: 9.186 ± 0.048	4.99LeuThr: 4.99 ± 0.032	5.877LeuVal: 5.877 ± 0.038	0.955LeuTrp: 0.955 ± 0.014	2.481LeuTyr: 2.481 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.115MetAla: 2.115 ± 0.025	0.376MetCys: 0.376 ± 0.009	1.689MetAsp: 1.689 ± 0.019	1.338MetGlu: 1.338 ± 0.019	0.85MetPhe: 0.85 ± 0.013	1.438MetGly: 1.438 ± 0.02	0.747MetHis: 0.747 ± 0.012	1.259MetIle: 1.259 ± 0.017	1.054MetLys: 1.054 ± 0.014	2.267MetLeu: 2.267 ± 0.022	0.669MetMet: 0.669 ± 0.011	0.959MetAsn: 0.959 ± 0.013	1.265MetPro: 1.265 ± 0.017	1.108MetGln: 1.108 ± 0.017	1.292MetArg: 1.292 ± 0.016	2.257MetSer: 2.257 ± 0.024	1.447MetThr: 1.447 ± 0.019	1.496MetVal: 1.496 ± 0.019	0.225MetTrp: 0.225 ± 0.008	0.671MetTyr: 0.671 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.034AsnAla: 3.034 ± 0.026	0.468AsnCys: 0.468 ± 0.01	2.392AsnAsp: 2.392 ± 0.023	2.039AsnGlu: 2.039 ± 0.021	1.158AsnPhe: 1.158 ± 0.015	2.597AsnGly: 2.597 ± 0.026	1.086AsnHis: 1.086 ± 0.016	2.518AsnIle: 2.518 ± 0.022	1.701AsnLys: 1.701 ± 0.019	3.4AsnLeu: 3.4 ± 0.025	1.057AsnMet: 1.057 ± 0.015	1.98AsnAsn: 1.98 ± 0.027	2.53AsnPro: 2.53 ± 0.024	1.616AsnGln: 1.616 ± 0.018	2.056AsnArg: 2.056 ± 0.02	4.079AsnSer: 4.079 ± 0.033	2.901AsnThr: 2.901 ± 0.026	2.346AsnVal: 2.346 ± 0.022	0.363AsnTrp: 0.363 ± 0.008	1.004AsnTyr: 1.004 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	3.861ProAla: 3.861 ± 0.034	0.594ProCys: 0.594 ± 0.012	2.69ProAsp: 2.69 ± 0.024	2.709ProGlu: 2.709 ± 0.022	1.961ProPhe: 1.961 ± 0.023	2.593ProGly: 2.593 ± 0.03	1.5ProHis: 1.5 ± 0.019	3.119ProIle: 3.119 ± 0.028	2.496ProLys: 2.496 ± 0.027	5.182ProLeu: 5.182 ± 0.041	1.108ProMet: 1.108 ± 0.016	2.19ProAsn: 2.19 ± 0.024	3.974ProPro: 3.974 ± 0.062	2.212ProGln: 2.212 ± 0.028	2.347ProArg: 2.347 ± 0.023	6.164ProSer: 6.164 ± 0.052	4.132ProThr: 4.132 ± 0.039	3.287ProVal: 3.287 ± 0.027	0.429ProTrp: 0.429 ± 0.01	1.351ProTyr: 1.351 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	2.829GlnAla: 2.829 ± 0.024	0.57GlnCys: 0.57 ± 0.01	2.139GlnAsp: 2.139 ± 0.022	2.283GlnGlu: 2.283 ± 0.026	1.383GlnPhe: 1.383 ± 0.016	1.947GlnGly: 1.947 ± 0.022	1.492GlnHis: 1.492 ± 0.021	2.317GlnIle: 2.317 ± 0.021	2.125GlnLys: 2.125 ± 0.023	4.328GlnLeu: 4.328 ± 0.04	1.078GlnMet: 1.078 ± 0.016	1.593GlnAsn: 1.593 ± 0.02	2.532GlnPro: 2.532 ± 0.028	4.055GlnGln: 4.055 ± 0.11	2.544GlnArg: 2.544 ± 0.026	4.203GlnSer: 4.203 ± 0.037	2.547GlnThr: 2.547 ± 0.021	2.158GlnVal: 2.158 ± 0.02	0.412GlnTrp: 0.412 ± 0.009	1.198GlnTyr: 1.198 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	3.342ArgAla: 3.342 ± 0.025	0.714ArgCys: 0.714 ± 0.012	2.916ArgAsp: 2.916 ± 0.033	2.656ArgGlu: 2.656 ± 0.029	1.926ArgPhe: 1.926 ± 0.019	2.698ArgGly: 2.698 ± 0.029	1.578ArgHis: 1.578 ± 0.018	3.218ArgIle: 3.218 ± 0.028	2.923ArgLys: 2.923 ± 0.024	5.305ArgLeu: 5.305 ± 0.036	1.327ArgMet: 1.327 ± 0.018	2.14ArgAsn: 2.14 ± 0.021	2.603ArgPro: 2.603 ± 0.025	2.388ArgGln: 2.388 ± 0.022	3.573ArgArg: 3.573 ± 0.036	4.971ArgSer: 4.971 ± 0.042	2.936ArgThr: 2.936 ± 0.025	2.974ArgVal: 2.974 ± 0.022	0.538ArgTrp: 0.538 ± 0.009	1.447ArgTyr: 1.447 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	7.389SerAla: 7.389 ± 0.045	1.224SerCys: 1.224 ± 0.017	5.563SerAsp: 5.563 ± 0.038	4.481SerGlu: 4.481 ± 0.03	3.406SerPhe: 3.406 ± 0.028	5.931SerGly: 5.931 ± 0.041	2.866SerHis: 2.866 ± 0.025	5.83SerIle: 5.83 ± 0.037	4.892SerLys: 4.892 ± 0.037	9.239SerLeu: 9.239 ± 0.053	2.275SerMet: 2.275 ± 0.02	4.543SerAsn: 4.543 ± 0.028	5.489SerPro: 5.489 ± 0.049	3.983SerGln: 3.983 ± 0.033	5.089SerArg: 5.089 ± 0.044	12.176SerSer: 12.176 ± 0.08	7.794SerThr: 7.794 ± 0.05	5.805SerVal: 5.805 ± 0.037	0.831SerTrp: 0.831 ± 0.012	2.265SerTyr: 2.265 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.375ThrAla: 5.375 ± 0.044	0.83ThrCys: 0.83 ± 0.016	3.408ThrAsp: 3.408 ± 0.024	2.936ThrGlu: 2.936 ± 0.022	2.051ThrPhe: 2.051 ± 0.022	3.761ThrGly: 3.761 ± 0.028	1.924ThrHis: 1.924 ± 0.02	3.679ThrIle: 3.679 ± 0.03	3.002ThrLys: 3.002 ± 0.023	6.182ThrLeu: 6.182 ± 0.036	1.452ThrMet: 1.452 ± 0.015	2.587ThrAsn: 2.587 ± 0.021	4.271ThrPro: 4.271 ± 0.039	2.415ThrGln: 2.415 ± 0.023	2.889ThrArg: 2.889 ± 0.027	6.473ThrSer: 6.473 ± 0.05	6.195ThrThr: 6.195 ± 0.068	3.97ThrVal: 3.97 ± 0.031	0.559ThrTrp: 0.559 ± 0.01	1.45ThrTyr: 1.45 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	4.942ValAla: 4.942 ± 0.037	1.009ValCys: 1.009 ± 0.015	3.968ValAsp: 3.968 ± 0.027	3.241ValGlu: 3.241 ± 0.026	2.424ValPhe: 2.424 ± 0.018	3.483ValGly: 3.483 ± 0.03	1.656ValHis: 1.656 ± 0.017	3.12ValIle: 3.12 ± 0.023	2.77ValLys: 2.77 ± 0.025	5.739ValLeu: 5.739 ± 0.035	1.398ValMet: 1.398 ± 0.018	2.315ValAsn: 2.315 ± 0.019	3.105ValPro: 3.105 ± 0.024	2.383ValGln: 2.383 ± 0.022	2.954ValArg: 2.954 ± 0.026	5.916ValSer: 5.916 ± 0.035	3.285ValThr: 3.285 ± 0.025	4.47ValVal: 4.47 ± 0.038	0.661ValTrp: 0.661 ± 0.011	1.761ValTyr: 1.761 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	0.642TrpAla: 0.642 ± 0.011	0.166TrpCys: 0.166 ± 0.006	0.627TrpAsp: 0.627 ± 0.012	0.503TrpGlu: 0.503 ± 0.009	0.391TrpPhe: 0.391 ± 0.008	0.514TrpGly: 0.514 ± 0.009	0.245TrpHis: 0.245 ± 0.007	0.669TrpIle: 0.669 ± 0.011	0.575TrpLys: 0.575 ± 0.012	0.918TrpLeu: 0.918 ± 0.013	0.328TrpMet: 0.328 ± 0.009	0.482TrpAsn: 0.482 ± 0.009	0.365TrpPro: 0.365 ± 0.007	0.364TrpGln: 0.364 ± 0.008	0.592TrpArg: 0.592 ± 0.011	0.846TrpSer: 0.846 ± 0.013	0.649TrpThr: 0.649 ± 0.012	0.639TrpVal: 0.639 ± 0.013	0.156TrpTrp: 0.156 ± 0.006	0.265TrpTyr: 0.265 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.819TyrAla: 1.819 ± 0.017	0.418TyrCys: 0.418 ± 0.01	1.52TyrAsp: 1.52 ± 0.019	1.324TyrGlu: 1.324 ± 0.018	1.118TyrPhe: 1.118 ± 0.014	1.664TyrGly: 1.664 ± 0.021	0.733TyrHis: 0.733 ± 0.012	1.705TyrIle: 1.705 ± 0.018	1.223TyrLys: 1.223 ± 0.016	2.545TyrLeu: 2.545 ± 0.027	0.696TyrMet: 0.696 ± 0.012	1.179TyrAsn: 1.179 ± 0.015	1.3TyrPro: 1.3 ± 0.017	1.18TyrGln: 1.18 ± 0.016	1.432TyrArg: 1.432 ± 0.016	2.475TyrSer: 2.475 ± 0.024	1.716TyrThr: 1.716 ± 0.02	1.477TyrVal: 1.477 ± 0.017	0.294TyrTrp: 0.294 ± 0.008	0.83TyrTyr: 0.83 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11933 proteins (5546497 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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