Amino acid dipepetide frequency for Garlic virus X

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.118AlaAla: 5.118 ± 2.059
2.362AlaCys: 2.362 ± 1.006
2.756AlaAsp: 2.756 ± 0.993
5.118AlaGlu: 5.118 ± 1.696
3.15AlaPhe: 3.15 ± 1.066
2.756AlaGly: 2.756 ± 1.273
2.756AlaHis: 2.756 ± 1.196
3.15AlaIle: 3.15 ± 1.441
5.906AlaLys: 5.906 ± 1.204
9.449AlaLeu: 9.449 ± 3.145
1.969AlaMet: 1.969 ± 1.086
4.331AlaAsn: 4.331 ± 0.498
2.362AlaPro: 2.362 ± 1.205
3.543AlaGln: 3.543 ± 1.666
2.362AlaArg: 2.362 ± 1.026
5.906AlaSer: 5.906 ± 1.903
5.118AlaThr: 5.118 ± 0.894
2.362AlaVal: 2.362 ± 0.868
0.394AlaTrp: 0.394 ± 0.627
3.937AlaTyr: 3.937 ± 1.238
0.0AlaXaa: 0.0 ± 0.0
Cys
0.787CysAla: 0.787 ± 0.684
0.0CysCys: 0.0 ± 0.0
1.181CysAsp: 1.181 ± 0.552
0.787CysGlu: 0.787 ± 0.434
1.181CysPhe: 1.181 ± 0.651
2.756CysGly: 2.756 ± 1.979
0.394CysHis: 0.394 ± 0.217
0.0CysIle: 0.0 ± 0.0
1.575CysLys: 1.575 ± 0.689
2.362CysLeu: 2.362 ± 1.547
0.394CysMet: 0.394 ± 0.549
1.181CysAsn: 1.181 ± 0.652
0.787CysPro: 0.787 ± 0.538
1.181CysGln: 1.181 ± 1.224
1.181CysArg: 1.181 ± 0.552
0.787CysSer: 0.787 ± 0.692
0.787CysThr: 0.787 ± 0.526
0.394CysVal: 0.394 ± 0.73
0.0CysTrp: 0.0 ± 0.0
1.181CysTyr: 1.181 ± 1.138
0.0CysXaa: 0.0 ± 0.0
Asp
2.756AspAla: 2.756 ± 1.053
1.575AspCys: 1.575 ± 1.368
2.756AspAsp: 2.756 ± 1.143
6.299AspGlu: 6.299 ± 1.987
4.724AspPhe: 4.724 ± 0.911
2.362AspGly: 2.362 ± 0.856
1.575AspHis: 1.575 ± 0.808
1.969AspIle: 1.969 ± 0.77
2.756AspLys: 2.756 ± 1.112
5.906AspLeu: 5.906 ± 1.777
0.787AspMet: 0.787 ± 0.434
1.575AspAsn: 1.575 ± 0.808
2.756AspPro: 2.756 ± 1.196
2.362AspGln: 2.362 ± 0.957
2.756AspArg: 2.756 ± 1.053
5.512AspSer: 5.512 ± 1.351
3.543AspThr: 3.543 ± 1.43
3.15AspVal: 3.15 ± 0.979
0.787AspTrp: 0.787 ± 0.434
2.756AspTyr: 2.756 ± 1.053
0.0AspXaa: 0.0 ± 0.0
Glu
4.331GluAla: 4.331 ± 0.498
0.394GluCys: 0.394 ± 0.217
3.937GluAsp: 3.937 ± 1.158
2.362GluGlu: 2.362 ± 1.016
1.575GluPhe: 1.575 ± 0.601
1.575GluGly: 1.575 ± 0.947
0.787GluHis: 0.787 ± 0.538
3.937GluIle: 3.937 ± 1.054
3.15GluLys: 3.15 ± 1.286
3.543GluLeu: 3.543 ± 1.412
0.787GluMet: 0.787 ± 0.538
2.756GluAsn: 2.756 ± 1.053
3.15GluPro: 3.15 ± 1.002
2.756GluGln: 2.756 ± 0.725
3.937GluArg: 3.937 ± 0.821
6.299GluSer: 6.299 ± 1.599
5.118GluThr: 5.118 ± 0.977
3.937GluVal: 3.937 ± 1.132
0.394GluTrp: 0.394 ± 0.608
0.787GluTyr: 0.787 ± 0.579
0.0GluXaa: 0.0 ± 0.0
Phe
2.362PheAla: 2.362 ± 0.778
0.787PheCys: 0.787 ± 0.526
3.543PheAsp: 3.543 ± 1.469
3.15PheGlu: 3.15 ± 1.202
1.575PhePhe: 1.575 ± 0.897
1.969PheGly: 1.969 ± 1.548
1.575PheHis: 1.575 ± 0.642
2.362PheIle: 2.362 ± 1.143
3.15PheLys: 3.15 ± 1.066
2.756PheLeu: 2.756 ± 1.353
1.575PheMet: 1.575 ± 0.572
2.756PheAsn: 2.756 ± 0.93
1.575PhePro: 1.575 ± 0.869
2.362PheGln: 2.362 ± 0.629
1.181PheArg: 1.181 ± 0.801
1.969PheSer: 1.969 ± 0.79
4.724PheThr: 4.724 ± 1.862
1.575PheVal: 1.575 ± 0.808
0.0PheTrp: 0.0 ± 0.0
1.181PheTyr: 1.181 ± 0.652
0.0PheXaa: 0.0 ± 0.0
Gly
4.724GlyAla: 4.724 ± 1.276
1.575GlyCys: 1.575 ± 1.158
4.724GlyAsp: 4.724 ± 1.02
1.575GlyGlu: 1.575 ± 0.642
1.181GlyPhe: 1.181 ± 0.793
3.543GlyGly: 3.543 ± 1.123
1.181GlyHis: 1.181 ± 0.505
1.575GlyIle: 1.575 ± 0.572
3.543GlyLys: 3.543 ± 1.091
4.331GlyLeu: 4.331 ± 0.771
1.575GlyMet: 1.575 ± 1.053
1.575GlyAsn: 1.575 ± 0.839
2.756GlyPro: 2.756 ± 1.761
0.787GlyGln: 0.787 ± 0.434
2.362GlyArg: 2.362 ± 1.584
0.787GlySer: 0.787 ± 0.881
3.15GlyThr: 3.15 ± 1.59
2.362GlyVal: 2.362 ± 2.449
1.181GlyTrp: 1.181 ± 0.652
1.181GlyTyr: 1.181 ± 0.505
0.0GlyXaa: 0.0 ± 0.0
His
3.543HisAla: 3.543 ± 1.656
0.394HisCys: 0.394 ± 0.217
1.181HisAsp: 1.181 ± 0.552
2.362HisGlu: 2.362 ± 1.383
2.362HisPhe: 2.362 ± 0.802
1.969HisGly: 1.969 ± 0.751
0.787HisHis: 0.787 ± 0.538
1.575HisIle: 1.575 ± 0.601
0.0HisLys: 0.0 ± 0.0
3.543HisLeu: 3.543 ± 1.537
0.394HisMet: 0.394 ± 0.584
0.787HisAsn: 0.787 ± 0.526
0.787HisPro: 0.787 ± 0.852
2.362HisGln: 2.362 ± 0.802
1.969HisArg: 1.969 ± 1.548
3.543HisSer: 3.543 ± 0.96
1.181HisThr: 1.181 ± 0.72
2.362HisVal: 2.362 ± 0.643
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.15IleAla: 3.15 ± 0.844
0.787IleCys: 0.787 ± 0.579
2.362IleAsp: 2.362 ± 0.957
4.331IleGlu: 4.331 ± 1.504
1.969IlePhe: 1.969 ± 0.77
1.181IleGly: 1.181 ± 0.652
2.362IleHis: 2.362 ± 1.042
2.362IleIle: 2.362 ± 1.461
3.15IleLys: 3.15 ± 1.285
3.15IleLeu: 3.15 ± 0.942
1.575IleMet: 1.575 ± 0.572
3.15IleAsn: 3.15 ± 2.183
1.575IlePro: 1.575 ± 0.643
3.15IleGln: 3.15 ± 1.586
3.543IleArg: 3.543 ± 0.636
2.756IleSer: 2.756 ± 1.003
4.724IleThr: 4.724 ± 1.603
3.15IleVal: 3.15 ± 0.748
0.394IleTrp: 0.394 ± 0.73
1.181IleTyr: 1.181 ± 1.014
0.0IleXaa: 0.0 ± 0.0
Lys
4.724LysAla: 4.724 ± 1.189
0.787LysCys: 0.787 ± 0.952
3.15LysAsp: 3.15 ± 1.144
1.969LysGlu: 1.969 ± 1.13
1.969LysPhe: 1.969 ± 0.812
0.787LysGly: 0.787 ± 0.526
1.181LysHis: 1.181 ± 0.652
3.543LysIle: 3.543 ± 1.015
1.969LysLys: 1.969 ± 1.086
7.874LysLeu: 7.874 ± 2.363
0.394LysMet: 0.394 ± 1.07
0.787LysAsn: 0.787 ± 0.434
4.331LysPro: 4.331 ± 1.995
0.787LysGln: 0.787 ± 0.526
4.331LysArg: 4.331 ± 1.385
5.512LysSer: 5.512 ± 0.993
4.331LysThr: 4.331 ± 1.595
1.575LysVal: 1.575 ± 0.642
0.394LysTrp: 0.394 ± 0.217
1.181LysTyr: 1.181 ± 0.552
0.0LysXaa: 0.0 ± 0.0
Leu
9.843LeuAla: 9.843 ± 2.582
1.969LeuCys: 1.969 ± 0.786
4.331LeuAsp: 4.331 ± 1.243
4.331LeuGlu: 4.331 ± 1.092
5.512LeuPhe: 5.512 ± 0.58
5.118LeuGly: 5.118 ± 2.203
2.756LeuHis: 2.756 ± 1.533
6.693LeuIle: 6.693 ± 2.621
3.15LeuLys: 3.15 ± 1.249
9.449LeuLeu: 9.449 ± 1.948
1.969LeuMet: 1.969 ± 0.8
3.937LeuAsn: 3.937 ± 2.216
9.055LeuPro: 9.055 ± 1.656
3.937LeuGln: 3.937 ± 1.331
4.724LeuArg: 4.724 ± 1.332
7.48LeuSer: 7.48 ± 1.393
8.268LeuThr: 8.268 ± 1.444
3.15LeuVal: 3.15 ± 0.844
1.181LeuTrp: 1.181 ± 0.652
4.331LeuTyr: 4.331 ± 1.252
0.0LeuXaa: 0.0 ± 0.0
Met
0.787MetAla: 0.787 ± 0.434
0.394MetCys: 0.394 ± 0.217
1.181MetAsp: 1.181 ± 0.552
1.181MetGlu: 1.181 ± 0.652
0.394MetPhe: 0.394 ± 0.217
0.787MetGly: 0.787 ± 0.881
0.394MetHis: 0.394 ± 0.779
0.0MetIle: 0.0 ± 0.0
0.787MetLys: 0.787 ± 1.174
0.787MetLeu: 0.787 ± 0.526
0.787MetMet: 0.787 ± 0.434
0.787MetAsn: 0.787 ± 0.526
1.181MetPro: 1.181 ± 1.138
1.575MetGln: 1.575 ± 0.869
0.787MetArg: 0.787 ± 0.526
2.362MetSer: 2.362 ± 1.364
3.15MetThr: 3.15 ± 0.856
0.787MetVal: 0.787 ± 0.526
0.0MetTrp: 0.0 ± 0.0
0.394MetTyr: 0.394 ± 0.608
0.0MetXaa: 0.0 ± 0.0
Asn
4.331AsnAla: 4.331 ± 1.965
1.181AsnCys: 1.181 ± 0.652
1.969AsnAsp: 1.969 ± 0.79
0.394AsnGlu: 0.394 ± 0.217
1.181AsnPhe: 1.181 ± 0.704
1.181AsnGly: 1.181 ± 0.901
2.362AsnHis: 2.362 ± 0.797
1.969AsnIle: 1.969 ± 1.065
2.756AsnLys: 2.756 ± 1.044
5.512AsnLeu: 5.512 ± 1.45
0.787AsnMet: 0.787 ± 0.526
2.362AsnAsn: 2.362 ± 0.611
4.724AsnPro: 4.724 ± 0.84
2.362AsnGln: 2.362 ± 2.557
2.362AsnArg: 2.362 ± 1.035
4.724AsnSer: 4.724 ± 2.628
4.331AsnThr: 4.331 ± 2.03
1.969AsnVal: 1.969 ± 1.086
0.394AsnTrp: 0.394 ± 0.627
1.969AsnTyr: 1.969 ± 1.086
0.0AsnXaa: 0.0 ± 0.0
Pro
4.331ProAla: 4.331 ± 2.228
0.394ProCys: 0.394 ± 0.627
3.15ProAsp: 3.15 ± 1.46
4.724ProGlu: 4.724 ± 1.913
1.969ProPhe: 1.969 ± 0.928
2.756ProGly: 2.756 ± 1.071
2.362ProHis: 2.362 ± 1.439
1.969ProIle: 1.969 ± 0.77
4.331ProLys: 4.331 ± 1.393
4.724ProLeu: 4.724 ± 0.802
0.394ProMet: 0.394 ± 0.608
3.543ProAsn: 3.543 ± 1.06
5.118ProPro: 5.118 ± 3.111
0.787ProGln: 0.787 ± 0.434
3.15ProArg: 3.15 ± 0.942
3.15ProSer: 3.15 ± 0.602
7.48ProThr: 7.48 ± 1.354
4.331ProVal: 4.331 ± 1.392
0.787ProTrp: 0.787 ± 0.434
1.181ProTyr: 1.181 ± 0.572
0.0ProXaa: 0.0 ± 0.0
Gln
1.969GlnAla: 1.969 ± 0.702
0.394GlnCys: 0.394 ± 0.608
1.969GlnAsp: 1.969 ± 0.786
1.181GlnGlu: 1.181 ± 1.138
1.575GlnPhe: 1.575 ± 1.278
3.543GlnGly: 3.543 ± 2.38
1.181GlnHis: 1.181 ± 0.552
3.543GlnIle: 3.543 ± 0.762
0.394GlnLys: 0.394 ± 0.217
7.087GlnLeu: 7.087 ± 2.67
0.0GlnMet: 0.0 ± 0.0
3.543GlnAsn: 3.543 ± 1.666
3.15GlnPro: 3.15 ± 1.339
3.543GlnGln: 3.543 ± 1.64
1.969GlnArg: 1.969 ± 0.702
4.331GlnSer: 4.331 ± 1.912
1.969GlnThr: 1.969 ± 1.086
2.756GlnVal: 2.756 ± 0.71
0.394GlnTrp: 0.394 ± 0.217
0.787GlnTyr: 0.787 ± 0.579
0.0GlnXaa: 0.0 ± 0.0
Arg
6.299ArgAla: 6.299 ± 0.848
1.181ArgCys: 1.181 ± 1.28
3.15ArgAsp: 3.15 ± 1.14
5.512ArgGlu: 5.512 ± 1.191
2.756ArgPhe: 2.756 ± 1.337
1.181ArgGly: 1.181 ± 0.704
0.0ArgHis: 0.0 ± 0.0
1.969ArgIle: 1.969 ± 0.893
3.543ArgLys: 3.543 ± 2.034
5.118ArgLeu: 5.118 ± 2.375
0.394ArgMet: 0.394 ± 0.608
2.362ArgAsn: 2.362 ± 1.383
2.756ArgPro: 2.756 ± 1.057
2.756ArgGln: 2.756 ± 0.712
5.118ArgArg: 5.118 ± 1.753
3.15ArgSer: 3.15 ± 1.37
2.756ArgThr: 2.756 ± 1.291
3.15ArgVal: 3.15 ± 1.142
0.394ArgTrp: 0.394 ± 0.217
1.969ArgTyr: 1.969 ± 1.0
0.0ArgXaa: 0.0 ± 0.0
Ser
3.15SerAla: 3.15 ± 1.304
0.787SerCys: 0.787 ± 0.579
8.661SerAsp: 8.661 ± 1.76
3.543SerGlu: 3.543 ± 1.009
1.969SerPhe: 1.969 ± 2.133
2.362SerGly: 2.362 ± 0.868
3.15SerHis: 3.15 ± 1.95
3.543SerIle: 3.543 ± 1.087
4.331SerLys: 4.331 ± 1.217
5.512SerLeu: 5.512 ± 1.959
0.787SerMet: 0.787 ± 0.922
5.118SerAsn: 5.118 ± 2.164
3.543SerPro: 3.543 ± 0.972
3.543SerGln: 3.543 ± 1.955
3.543SerArg: 3.543 ± 0.993
5.906SerSer: 5.906 ± 1.956
7.087SerThr: 7.087 ± 2.018
4.331SerVal: 4.331 ± 2.043
0.394SerTrp: 0.394 ± 0.217
2.756SerTyr: 2.756 ± 1.006
0.0SerXaa: 0.0 ± 0.0
Thr
5.512ThrAla: 5.512 ± 1.903
1.181ThrCys: 1.181 ± 0.505
4.724ThrAsp: 4.724 ± 1.574
2.756ThrGlu: 2.756 ± 1.179
3.543ThrPhe: 3.543 ± 0.883
4.331ThrGly: 4.331 ± 1.419
4.331ThrHis: 4.331 ± 1.078
4.331ThrIle: 4.331 ± 1.169
2.362ThrLys: 2.362 ± 1.097
11.417ThrLeu: 11.417 ± 3.438
1.181ThrMet: 1.181 ± 0.505
4.724ThrAsn: 4.724 ± 1.93
5.512ThrPro: 5.512 ± 0.821
3.937ThrGln: 3.937 ± 1.481
4.331ThrArg: 4.331 ± 1.926
6.299ThrSer: 6.299 ± 1.476
5.512ThrThr: 5.512 ± 1.323
3.15ThrVal: 3.15 ± 1.613
0.394ThrTrp: 0.394 ± 0.217
1.575ThrTyr: 1.575 ± 0.642
0.0ThrXaa: 0.0 ± 0.0
Val
2.362ValAla: 2.362 ± 0.548
1.181ValCys: 1.181 ± 1.014
1.181ValAsp: 1.181 ± 0.652
2.756ValGlu: 2.756 ± 0.71
2.756ValPhe: 2.756 ± 0.722
2.362ValGly: 2.362 ± 0.851
1.181ValHis: 1.181 ± 0.704
4.331ValIle: 4.331 ± 1.13
2.362ValLys: 2.362 ± 0.957
4.724ValLeu: 4.724 ± 1.223
1.969ValMet: 1.969 ± 0.574
1.969ValAsn: 1.969 ± 1.086
3.15ValPro: 3.15 ± 1.586
2.362ValGln: 2.362 ± 0.629
4.331ValArg: 4.331 ± 0.915
1.969ValSer: 1.969 ± 1.497
4.331ValThr: 4.331 ± 1.158
1.575ValVal: 1.575 ± 0.642
0.394ValTrp: 0.394 ± 0.217
0.787ValTyr: 0.787 ± 0.579
0.0ValXaa: 0.0 ± 0.0
Trp
0.787TrpAla: 0.787 ± 0.526
0.0TrpCys: 0.0 ± 0.0
0.394TrpAsp: 0.394 ± 0.217
0.394TrpGlu: 0.394 ± 0.217
0.394TrpPhe: 0.394 ± 0.217
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.787TrpLys: 0.787 ± 0.434
0.787TrpLeu: 0.787 ± 0.538
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.181TrpPro: 1.181 ± 0.72
0.0TrpGln: 0.0 ± 0.0
0.394TrpArg: 0.394 ± 0.217
0.787TrpSer: 0.787 ± 0.526
0.787TrpThr: 0.787 ± 0.434
1.181TrpVal: 1.181 ± 0.652
0.394TrpTrp: 0.394 ± 0.73
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.937TyrAla: 3.937 ± 1.214
1.575TyrCys: 1.575 ± 0.572
2.362TyrAsp: 2.362 ± 0.927
0.787TyrGlu: 0.787 ± 0.579
0.394TyrPhe: 0.394 ± 0.217
3.15TyrGly: 3.15 ± 0.977
0.787TyrHis: 0.787 ± 0.947
1.181TyrIle: 1.181 ± 0.652
1.969TyrLys: 1.969 ± 1.121
3.15TyrLeu: 3.15 ± 1.737
0.394TyrMet: 0.394 ± 0.217
1.575TyrAsn: 1.575 ± 0.94
1.181TyrPro: 1.181 ± 0.652
1.181TyrGln: 1.181 ± 0.572
1.181TyrArg: 1.181 ± 0.831
0.787TyrSer: 0.787 ± 0.434
2.756TyrThr: 2.756 ± 1.122
0.787TyrVal: 0.787 ± 0.526
0.0TyrTrp: 0.0 ± 0.0
1.181TyrTyr: 1.181 ± 0.505
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2541 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski