Amino acid dipepetide frequency for Tortoise microvirus 18

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.965AlaAla: 6.965 ± 3.808
0.0AlaCys: 0.0 ± 0.0
2.902AlaAsp: 2.902 ± 1.914
7.545AlaGlu: 7.545 ± 3.894
1.161AlaPhe: 1.161 ± 0.518
2.322AlaGly: 2.322 ± 0.985
0.58AlaHis: 0.58 ± 0.578
3.482AlaIle: 3.482 ± 1.173
4.643AlaLys: 4.643 ± 1.626
4.643AlaLeu: 4.643 ± 1.445
1.161AlaMet: 1.161 ± 0.615
4.643AlaAsn: 4.643 ± 0.949
1.161AlaPro: 1.161 ± 0.518
5.804AlaGln: 5.804 ± 3.054
2.902AlaArg: 2.902 ± 1.396
3.482AlaSer: 3.482 ± 0.903
4.643AlaThr: 4.643 ± 1.448
3.482AlaVal: 3.482 ± 1.758
1.161AlaTrp: 1.161 ± 0.492
2.322AlaTyr: 2.322 ± 0.967
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.161CysGlu: 1.161 ± 1.083
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.161CysIle: 1.161 ± 0.776
0.58CysLys: 0.58 ± 0.766
0.58CysLeu: 0.58 ± 0.541
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.58CysArg: 0.58 ± 0.541
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.902AspAla: 2.902 ± 1.231
0.0AspCys: 0.0 ± 0.0
2.902AspAsp: 2.902 ± 0.993
3.482AspGlu: 3.482 ± 1.358
1.161AspPhe: 1.161 ± 0.776
2.322AspGly: 2.322 ± 0.762
0.58AspHis: 0.58 ± 0.541
4.063AspIle: 4.063 ± 1.331
1.161AspLys: 1.161 ± 0.749
4.643AspLeu: 4.643 ± 1.956
0.58AspMet: 0.58 ± 0.382
0.58AspAsn: 0.58 ± 0.541
0.58AspPro: 0.58 ± 0.382
2.902AspGln: 2.902 ± 0.888
2.902AspArg: 2.902 ± 1.038
0.58AspSer: 0.58 ± 0.382
2.902AspThr: 2.902 ± 0.888
2.902AspVal: 2.902 ± 1.312
0.58AspTrp: 0.58 ± 0.382
3.482AspTyr: 3.482 ± 0.962
0.0AspXaa: 0.0 ± 0.0
Glu
7.545GluAla: 7.545 ± 1.971
1.161GluCys: 1.161 ± 1.083
1.741GluAsp: 1.741 ± 0.988
11.027GluGlu: 11.027 ± 1.559
4.063GluPhe: 4.063 ± 0.895
5.223GluGly: 5.223 ± 1.269
1.161GluHis: 1.161 ± 0.492
9.867GluIle: 9.867 ± 2.672
10.447GluLys: 10.447 ± 4.341
7.545GluLeu: 7.545 ± 2.233
4.063GluMet: 4.063 ± 0.989
6.384GluAsn: 6.384 ± 2.596
0.58GluPro: 0.58 ± 0.382
2.902GluGln: 2.902 ± 1.246
5.804GluArg: 5.804 ± 2.379
4.063GluSer: 4.063 ± 0.946
6.384GluThr: 6.384 ± 3.442
2.322GluVal: 2.322 ± 0.967
0.58GluTrp: 0.58 ± 0.541
7.545GluTyr: 7.545 ± 3.936
0.0GluXaa: 0.0 ± 0.0
Phe
1.741PheAla: 1.741 ± 1.147
0.0PheCys: 0.0 ± 0.0
1.741PheAsp: 1.741 ± 0.666
1.161PheGlu: 1.161 ± 0.695
1.741PhePhe: 1.741 ± 1.017
1.741PheGly: 1.741 ± 0.666
0.0PheHis: 0.0 ± 0.0
1.161PheIle: 1.161 ± 0.829
2.902PheLys: 2.902 ± 1.687
1.741PheLeu: 1.741 ± 0.903
1.161PheMet: 1.161 ± 0.838
2.902PheAsn: 2.902 ± 1.051
1.161PhePro: 1.161 ± 0.764
0.58PheGln: 0.58 ± 0.382
1.161PheArg: 1.161 ± 0.884
1.741PheSer: 1.741 ± 0.769
3.482PheThr: 3.482 ± 0.708
1.161PheVal: 1.161 ± 1.083
1.161PheTrp: 1.161 ± 0.492
1.161PheTyr: 1.161 ± 0.492
0.0PheXaa: 0.0 ± 0.0
Gly
6.384GlyAla: 6.384 ± 2.168
0.58GlyCys: 0.58 ± 0.766
3.482GlyAsp: 3.482 ± 1.092
8.125GlyGlu: 8.125 ± 2.515
2.322GlyPhe: 2.322 ± 1.047
7.545GlyGly: 7.545 ± 3.94
0.58GlyHis: 0.58 ± 0.541
7.545GlyIle: 7.545 ± 2.065
6.384GlyLys: 6.384 ± 1.678
4.063GlyLeu: 4.063 ± 1.505
2.322GlyMet: 2.322 ± 0.967
4.063GlyAsn: 4.063 ± 1.766
1.161GlyPro: 1.161 ± 0.764
2.322GlyGln: 2.322 ± 1.047
2.322GlyArg: 2.322 ± 1.529
4.063GlySer: 4.063 ± 1.328
8.125GlyThr: 8.125 ± 3.388
1.161GlyVal: 1.161 ± 0.696
0.58GlyTrp: 0.58 ± 0.382
2.902GlyTyr: 2.902 ± 1.209
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.58HisAsp: 0.58 ± 0.382
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.161HisGly: 1.161 ± 0.518
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.741HisLys: 1.741 ± 0.769
1.161HisLeu: 1.161 ± 0.749
0.0HisMet: 0.0 ± 0.0
2.322HisAsn: 2.322 ± 0.573
1.161HisPro: 1.161 ± 0.518
0.0HisGln: 0.0 ± 0.0
0.58HisArg: 0.58 ± 0.905
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.58HisTrp: 0.58 ± 0.541
0.58HisTyr: 0.58 ± 0.578
0.0HisXaa: 0.0 ± 0.0
Ile
6.965IleAla: 6.965 ± 0.962
0.58IleCys: 0.58 ± 0.541
5.804IleAsp: 5.804 ± 1.879
6.965IleGlu: 6.965 ± 2.486
0.58IlePhe: 0.58 ± 0.905
6.384IleGly: 6.384 ± 1.754
0.0IleHis: 0.0 ± 0.0
4.643IleIle: 4.643 ± 1.25
7.545IleLys: 7.545 ± 4.025
4.063IleLeu: 4.063 ± 1.312
1.161IleMet: 1.161 ± 0.695
4.063IleAsn: 4.063 ± 1.477
0.58IlePro: 0.58 ± 0.382
1.161IleGln: 1.161 ± 0.492
4.643IleArg: 4.643 ± 1.937
4.643IleSer: 4.643 ± 2.012
3.482IleThr: 3.482 ± 1.301
5.223IleVal: 5.223 ± 1.948
0.0IleTrp: 0.0 ± 0.0
2.322IleTyr: 2.322 ± 1.445
0.0IleXaa: 0.0 ± 0.0
Lys
3.482LysAla: 3.482 ± 1.293
0.58LysCys: 0.58 ± 0.541
1.741LysAsp: 1.741 ± 1.219
6.965LysGlu: 6.965 ± 2.23
3.482LysPhe: 3.482 ± 0.856
4.063LysGly: 4.063 ± 1.709
1.741LysHis: 1.741 ± 1.172
6.384LysIle: 6.384 ± 2.48
9.286LysLys: 9.286 ± 2.94
6.965LysLeu: 6.965 ± 2.36
4.063LysMet: 4.063 ± 0.761
5.223LysAsn: 5.223 ± 1.356
2.902LysPro: 2.902 ± 1.203
6.965LysGln: 6.965 ± 1.771
5.804LysArg: 5.804 ± 2.056
4.643LysSer: 4.643 ± 2.691
7.545LysThr: 7.545 ± 2.001
1.741LysVal: 1.741 ± 1.007
1.741LysTrp: 1.741 ± 1.004
1.741LysTyr: 1.741 ± 1.26
0.0LysXaa: 0.0 ± 0.0
Leu
4.063LeuAla: 4.063 ± 1.385
0.0LeuCys: 0.0 ± 0.0
1.741LeuAsp: 1.741 ± 0.758
4.643LeuGlu: 4.643 ± 1.626
1.741LeuPhe: 1.741 ± 1.017
9.286LeuGly: 9.286 ± 2.321
3.482LeuHis: 3.482 ± 1.243
4.063LeuIle: 4.063 ± 1.341
6.384LeuLys: 6.384 ± 1.724
4.643LeuLeu: 4.643 ± 1.239
2.322LeuMet: 2.322 ± 1.119
5.804LeuAsn: 5.804 ± 2.229
2.322LeuPro: 2.322 ± 1.077
2.902LeuGln: 2.902 ± 1.066
2.322LeuArg: 2.322 ± 0.786
2.902LeuSer: 2.902 ± 1.396
5.804LeuThr: 5.804 ± 1.18
2.322LeuVal: 2.322 ± 0.967
0.58LeuTrp: 0.58 ± 0.541
2.902LeuTyr: 2.902 ± 1.064
0.0LeuXaa: 0.0 ± 0.0
Met
2.322MetAla: 2.322 ± 0.801
0.58MetCys: 0.58 ± 0.541
1.741MetAsp: 1.741 ± 1.147
3.482MetGlu: 3.482 ± 1.837
1.161MetPhe: 1.161 ± 0.764
1.161MetGly: 1.161 ± 0.492
0.0MetHis: 0.0 ± 0.0
0.58MetIle: 0.58 ± 0.578
2.902MetLys: 2.902 ± 1.317
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
4.063MetAsn: 4.063 ± 1.241
1.741MetPro: 1.741 ± 1.147
0.0MetGln: 0.0 ± 0.0
0.58MetArg: 0.58 ± 0.382
1.741MetSer: 1.741 ± 1.147
2.902MetThr: 2.902 ± 1.209
0.58MetVal: 0.58 ± 0.382
0.0MetTrp: 0.0 ± 0.0
1.741MetTyr: 1.741 ± 1.348
0.0MetXaa: 0.0 ± 0.0
Asn
3.482AsnAla: 3.482 ± 2.097
0.0AsnCys: 0.0 ± 0.0
2.322AsnAsp: 2.322 ± 1.405
9.286AsnGlu: 9.286 ± 2.209
0.58AsnPhe: 0.58 ± 0.689
4.643AsnGly: 4.643 ± 1.452
0.0AsnHis: 0.0 ± 0.0
4.063AsnIle: 4.063 ± 0.768
6.384AsnLys: 6.384 ± 1.569
2.322AsnLeu: 2.322 ± 0.967
1.741AsnMet: 1.741 ± 0.86
5.223AsnAsn: 5.223 ± 1.637
0.58AsnPro: 0.58 ± 0.578
2.902AsnGln: 2.902 ± 1.107
4.063AsnArg: 4.063 ± 0.916
6.965AsnSer: 6.965 ± 1.888
4.643AsnThr: 4.643 ± 1.622
1.741AsnVal: 1.741 ± 0.863
1.161AsnTrp: 1.161 ± 0.492
5.223AsnTyr: 5.223 ± 1.514
0.0AsnXaa: 0.0 ± 0.0
Pro
0.58ProAla: 0.58 ± 0.382
0.0ProCys: 0.0 ± 0.0
0.58ProAsp: 0.58 ± 0.541
1.741ProGlu: 1.741 ± 1.019
2.322ProPhe: 2.322 ± 1.049
1.741ProGly: 1.741 ± 0.546
0.0ProHis: 0.0 ± 0.0
2.322ProIle: 2.322 ± 0.573
1.161ProLys: 1.161 ± 0.518
4.643ProLeu: 4.643 ± 2.414
0.58ProMet: 0.58 ± 0.541
0.58ProAsn: 0.58 ± 0.382
0.58ProPro: 0.58 ± 0.541
0.0ProGln: 0.0 ± 0.0
0.58ProArg: 0.58 ± 0.382
1.161ProSer: 1.161 ± 0.518
1.741ProThr: 1.741 ± 1.209
2.322ProVal: 2.322 ± 1.047
0.0ProTrp: 0.0 ± 0.0
0.58ProTyr: 0.58 ± 0.382
0.0ProXaa: 0.0 ± 0.0
Gln
5.223GlnAla: 5.223 ± 2.428
0.0GlnCys: 0.0 ± 0.0
1.161GlnAsp: 1.161 ± 0.696
6.384GlnGlu: 6.384 ± 2.933
1.741GlnPhe: 1.741 ± 1.004
2.902GlnGly: 2.902 ± 1.312
0.0GlnHis: 0.0 ± 0.0
2.322GlnIle: 2.322 ± 0.967
5.804GlnLys: 5.804 ± 1.664
1.161GlnLeu: 1.161 ± 0.696
0.0GlnMet: 0.0 ± 0.0
3.482GlnAsn: 3.482 ± 1.167
2.322GlnPro: 2.322 ± 1.529
1.741GlnGln: 1.741 ± 0.663
1.161GlnArg: 1.161 ± 0.749
1.161GlnSer: 1.161 ± 0.492
1.161GlnThr: 1.161 ± 0.884
1.741GlnVal: 1.741 ± 0.732
0.58GlnTrp: 0.58 ± 0.766
1.161GlnTyr: 1.161 ± 0.492
0.0GlnXaa: 0.0 ± 0.0
Arg
2.902ArgAla: 2.902 ± 1.055
0.0ArgCys: 0.0 ± 0.0
1.161ArgAsp: 1.161 ± 0.518
4.063ArgGlu: 4.063 ± 1.273
2.322ArgPhe: 2.322 ± 1.139
3.482ArgGly: 3.482 ± 1.351
0.0ArgHis: 0.0 ± 0.0
5.223ArgIle: 5.223 ± 1.638
2.902ArgLys: 2.902 ± 1.537
6.965ArgLeu: 6.965 ± 1.742
0.0ArgMet: 0.0 ± 0.0
3.482ArgAsn: 3.482 ± 1.211
0.58ArgPro: 0.58 ± 0.905
1.741ArgGln: 1.741 ± 1.314
5.223ArgArg: 5.223 ± 2.611
2.322ArgSer: 2.322 ± 1.293
2.902ArgThr: 2.902 ± 1.099
2.902ArgVal: 2.902 ± 1.181
1.161ArgTrp: 1.161 ± 1.083
2.322ArgTyr: 2.322 ± 1.507
0.0ArgXaa: 0.0 ± 0.0
Ser
5.223SerAla: 5.223 ± 1.097
0.0SerCys: 0.0 ± 0.0
2.902SerAsp: 2.902 ± 1.014
4.643SerGlu: 4.643 ± 1.951
1.741SerPhe: 1.741 ± 0.732
5.804SerGly: 5.804 ± 0.764
0.58SerHis: 0.58 ± 0.382
2.902SerIle: 2.902 ± 1.595
2.322SerLys: 2.322 ± 1.024
5.804SerLeu: 5.804 ± 1.078
0.58SerMet: 0.58 ± 0.541
1.741SerAsn: 1.741 ± 0.666
2.322SerPro: 2.322 ± 1.127
1.741SerGln: 1.741 ± 0.863
2.322SerArg: 2.322 ± 1.604
6.965SerSer: 6.965 ± 3.309
5.223SerThr: 5.223 ± 1.862
2.322SerVal: 2.322 ± 1.186
1.741SerTrp: 1.741 ± 0.732
1.741SerTyr: 1.741 ± 0.926
0.0SerXaa: 0.0 ± 0.0
Thr
2.322ThrAla: 2.322 ± 0.762
0.58ThrCys: 0.58 ± 0.665
2.902ThrAsp: 2.902 ± 1.553
8.706ThrGlu: 8.706 ± 2.388
1.161ThrPhe: 1.161 ± 0.492
7.545ThrGly: 7.545 ± 2.293
0.58ThrHis: 0.58 ± 0.382
4.063ThrIle: 4.063 ± 1.441
8.706ThrLys: 8.706 ± 3.043
4.643ThrLeu: 4.643 ± 1.589
2.902ThrMet: 2.902 ± 1.463
5.804ThrAsn: 5.804 ± 0.938
2.322ThrPro: 2.322 ± 0.747
3.482ThrGln: 3.482 ± 1.19
1.741ThrArg: 1.741 ± 1.339
5.223ThrSer: 5.223 ± 1.678
4.063ThrThr: 4.063 ± 2.229
3.482ThrVal: 3.482 ± 1.811
1.741ThrTrp: 1.741 ± 0.74
4.063ThrTyr: 4.063 ± 1.766
0.0ThrXaa: 0.0 ± 0.0
Val
1.161ValAla: 1.161 ± 0.492
0.0ValCys: 0.0 ± 0.0
2.902ValAsp: 2.902 ± 0.881
5.804ValGlu: 5.804 ± 2.349
1.741ValPhe: 1.741 ± 0.86
1.741ValGly: 1.741 ± 0.732
0.0ValHis: 0.0 ± 0.0
1.741ValIle: 1.741 ± 0.86
2.322ValLys: 2.322 ± 0.762
1.161ValLeu: 1.161 ± 1.111
2.322ValMet: 2.322 ± 1.114
3.482ValAsn: 3.482 ± 1.285
1.161ValPro: 1.161 ± 0.518
0.0ValGln: 0.0 ± 0.0
4.643ValArg: 4.643 ± 1.931
2.322ValSer: 2.322 ± 1.529
2.902ValThr: 2.902 ± 1.064
1.161ValVal: 1.161 ± 0.764
0.0ValTrp: 0.0 ± 0.0
2.902ValTyr: 2.902 ± 1.911
0.0ValXaa: 0.0 ± 0.0
Trp
1.741TrpAla: 1.741 ± 0.666
0.0TrpCys: 0.0 ± 0.0
2.322TrpAsp: 2.322 ± 0.801
0.58TrpGlu: 0.58 ± 0.382
0.0TrpPhe: 0.0 ± 0.0
1.741TrpGly: 1.741 ± 0.546
0.0TrpHis: 0.0 ± 0.0
0.58TrpIle: 0.58 ± 0.578
1.741TrpLys: 1.741 ± 0.74
2.322TrpLeu: 2.322 ± 1.036
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.161TrpGln: 1.161 ± 0.749
0.58TrpArg: 0.58 ± 0.541
0.58TrpSer: 0.58 ± 0.578
1.161TrpThr: 1.161 ± 0.492
0.0TrpVal: 0.0 ± 0.0
0.58TrpTrp: 0.58 ± 0.382
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.58TyrAla: 0.58 ± 0.382
0.0TyrCys: 0.0 ± 0.0
0.58TyrAsp: 0.58 ± 0.578
4.643TyrGlu: 4.643 ± 1.722
0.58TyrPhe: 0.58 ± 0.905
5.223TyrGly: 5.223 ± 0.965
0.58TyrHis: 0.58 ± 0.382
4.643TyrIle: 4.643 ± 1.495
1.741TyrLys: 1.741 ± 1.26
1.161TyrLeu: 1.161 ± 0.492
1.741TyrMet: 1.741 ± 0.731
3.482TyrAsn: 3.482 ± 0.877
0.0TyrPro: 0.0 ± 0.0
2.902TyrGln: 2.902 ± 1.312
1.741TyrArg: 1.741 ± 0.988
4.063TyrSer: 4.063 ± 0.882
6.965TyrThr: 6.965 ± 1.494
2.902TyrVal: 2.902 ± 1.262
1.161TyrTrp: 1.161 ± 0.492
1.161TyrTyr: 1.161 ± 0.518
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1724 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski