Amino acid dipepetide frequency for Hubei sobemo-like virus 20

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.112AlaAla: 3.112 ± 1.878
0.0AlaCys: 0.0 ± 0.0
5.187AlaAsp: 5.187 ± 0.333
3.112AlaGlu: 3.112 ± 1.878
2.075AlaPhe: 2.075 ± 1.252
6.224AlaGly: 6.224 ± 2.024
1.037AlaHis: 1.037 ± 0.626
5.187AlaIle: 5.187 ± 0.333
2.075AlaLys: 2.075 ± 0.48
4.149AlaLeu: 4.149 ± 0.959
3.112AlaMet: 3.112 ± 1.878
2.075AlaAsn: 2.075 ± 1.252
0.0AlaPro: 0.0 ± 0.0
2.075AlaGln: 2.075 ± 1.252
5.187AlaArg: 5.187 ± 1.398
8.299AlaSer: 8.299 ± 5.008
4.149AlaThr: 4.149 ± 0.772
6.224AlaVal: 6.224 ± 0.293
1.037AlaTrp: 1.037 ± 0.626
4.149AlaTyr: 4.149 ± 0.959
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.037CysAsp: 1.037 ± 0.626
1.037CysGlu: 1.037 ± 0.626
0.0CysPhe: 0.0 ± 0.0
3.112CysGly: 3.112 ± 1.878
0.0CysHis: 0.0 ± 0.0
2.075CysIle: 2.075 ± 0.48
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.075CysPro: 2.075 ± 1.252
0.0CysGln: 0.0 ± 0.0
3.112CysArg: 3.112 ± 0.146
1.037CysSer: 1.037 ± 0.626
2.075CysThr: 2.075 ± 1.252
2.075CysVal: 2.075 ± 2.211
1.037CysTrp: 1.037 ± 1.106
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.075AspAla: 2.075 ± 2.211
0.0AspCys: 0.0 ± 0.0
2.075AspAsp: 2.075 ± 2.211
3.112AspGlu: 3.112 ± 1.878
3.112AspPhe: 3.112 ± 1.878
5.187AspGly: 5.187 ± 2.065
1.037AspHis: 1.037 ± 1.106
1.037AspIle: 1.037 ± 0.626
4.149AspLys: 4.149 ± 0.959
8.299AspLeu: 8.299 ± 5.381
0.0AspMet: 0.0 ± 0.0
1.037AspAsn: 1.037 ± 1.106
2.075AspPro: 2.075 ± 0.48
3.112AspGln: 3.112 ± 0.146
3.112AspArg: 3.112 ± 0.146
3.112AspSer: 3.112 ± 1.878
1.037AspThr: 1.037 ± 1.106
5.187AspVal: 5.187 ± 0.333
1.037AspTrp: 1.037 ± 1.106
1.037AspTyr: 1.037 ± 0.626
0.0AspXaa: 0.0 ± 0.0
Glu
5.187GluAla: 5.187 ± 1.398
0.0GluCys: 0.0 ± 0.0
3.112GluAsp: 3.112 ± 0.146
4.149GluGlu: 4.149 ± 0.772
1.037GluPhe: 1.037 ± 1.106
1.037GluGly: 1.037 ± 0.626
3.112GluHis: 3.112 ± 1.878
0.0GluIle: 0.0 ± 0.0
2.075GluLys: 2.075 ± 1.252
6.224GluLeu: 6.224 ± 0.293
5.187GluMet: 5.187 ± 0.333
2.075GluAsn: 2.075 ± 1.252
3.112GluPro: 3.112 ± 3.317
4.149GluGln: 4.149 ± 0.772
4.149GluArg: 4.149 ± 0.772
4.149GluSer: 4.149 ± 2.504
0.0GluThr: 0.0 ± 0.0
4.149GluVal: 4.149 ± 0.772
2.075GluTrp: 2.075 ± 0.48
1.037GluTyr: 1.037 ± 1.106
0.0GluXaa: 0.0 ± 0.0
Phe
2.075PheAla: 2.075 ± 0.48
1.037PheCys: 1.037 ± 1.106
3.112PheAsp: 3.112 ± 3.317
2.075PheGlu: 2.075 ± 2.211
0.0PhePhe: 0.0 ± 0.0
1.037PheGly: 1.037 ± 1.106
0.0PheHis: 0.0 ± 0.0
1.037PheIle: 1.037 ± 1.106
3.112PheLys: 3.112 ± 0.146
4.149PheLeu: 4.149 ± 0.772
0.0PheMet: 0.0 ± 0.0
1.037PheAsn: 1.037 ± 1.106
0.0PhePro: 0.0 ± 0.0
2.075PheGln: 2.075 ± 0.48
2.075PheArg: 2.075 ± 0.48
2.075PheSer: 2.075 ± 1.252
3.112PheThr: 3.112 ± 0.146
2.075PheVal: 2.075 ± 0.48
0.0PheTrp: 0.0 ± 0.0
1.037PheTyr: 1.037 ± 0.626
0.0PheXaa: 0.0 ± 0.0
Gly
6.224GlyAla: 6.224 ± 2.024
1.037GlyCys: 1.037 ± 1.106
4.149GlyAsp: 4.149 ± 0.959
5.187GlyGlu: 5.187 ± 0.333
1.037GlyPhe: 1.037 ± 1.106
3.112GlyGly: 3.112 ± 1.585
1.037GlyHis: 1.037 ± 1.106
5.187GlyIle: 5.187 ± 1.398
3.112GlyLys: 3.112 ± 0.146
4.149GlyLeu: 4.149 ± 0.772
3.112GlyMet: 3.112 ± 0.146
4.149GlyAsn: 4.149 ± 0.959
1.037GlyPro: 1.037 ± 0.626
2.075GlyGln: 2.075 ± 1.252
1.037GlyArg: 1.037 ± 0.626
4.149GlySer: 4.149 ± 2.504
1.037GlyThr: 1.037 ± 0.626
6.224GlyVal: 6.224 ± 3.756
2.075GlyTrp: 2.075 ± 2.211
3.112GlyTyr: 3.112 ± 1.585
0.0GlyXaa: 0.0 ± 0.0
His
1.037HisAla: 1.037 ± 0.626
1.037HisCys: 1.037 ± 0.626
1.037HisAsp: 1.037 ± 1.106
1.037HisGlu: 1.037 ± 0.626
0.0HisPhe: 0.0 ± 0.0
2.075HisGly: 2.075 ± 0.48
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.037HisLys: 1.037 ± 0.626
3.112HisLeu: 3.112 ± 1.585
1.037HisMet: 1.037 ± 1.106
0.0HisAsn: 0.0 ± 0.0
3.112HisPro: 3.112 ± 1.878
0.0HisGln: 0.0 ± 0.0
2.075HisArg: 2.075 ± 0.48
3.112HisSer: 3.112 ± 1.585
0.0HisThr: 0.0 ± 0.0
4.149HisVal: 4.149 ± 0.959
0.0HisTrp: 0.0 ± 0.0
1.037HisTyr: 1.037 ± 0.626
0.0HisXaa: 0.0 ± 0.0
Ile
4.149IleAla: 4.149 ± 0.772
2.075IleCys: 2.075 ± 1.252
2.075IleAsp: 2.075 ± 2.211
2.075IleGlu: 2.075 ± 1.252
2.075IlePhe: 2.075 ± 2.211
2.075IleGly: 2.075 ± 1.252
1.037IleHis: 1.037 ± 0.626
2.075IleIle: 2.075 ± 2.211
1.037IleLys: 1.037 ± 1.106
5.187IleLeu: 5.187 ± 3.13
3.112IleMet: 3.112 ± 0.146
0.0IleAsn: 0.0 ± 0.0
2.075IlePro: 2.075 ± 0.48
2.075IleGln: 2.075 ± 0.48
6.224IleArg: 6.224 ± 0.293
2.075IleSer: 2.075 ± 0.48
1.037IleThr: 1.037 ± 1.106
2.075IleVal: 2.075 ± 0.48
1.037IleTrp: 1.037 ± 0.626
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.075LysAla: 2.075 ± 1.252
1.037LysCys: 1.037 ± 1.106
0.0LysAsp: 0.0 ± 0.0
2.075LysGlu: 2.075 ± 1.252
2.075LysPhe: 2.075 ± 1.252
2.075LysGly: 2.075 ± 0.48
1.037LysHis: 1.037 ± 1.106
0.0LysIle: 0.0 ± 0.0
3.112LysLys: 3.112 ± 0.146
2.075LysLeu: 2.075 ± 1.252
3.112LysMet: 3.112 ± 1.585
1.037LysAsn: 1.037 ± 1.106
5.187LysPro: 5.187 ± 0.333
1.037LysGln: 1.037 ± 1.106
3.112LysArg: 3.112 ± 0.146
6.224LysSer: 6.224 ± 0.293
4.149LysThr: 4.149 ± 2.504
4.149LysVal: 4.149 ± 2.504
1.037LysTrp: 1.037 ± 1.106
4.149LysTyr: 4.149 ± 0.959
0.0LysXaa: 0.0 ± 0.0
Leu
6.224LeuAla: 6.224 ± 3.756
1.037LeuCys: 1.037 ± 1.106
3.112LeuAsp: 3.112 ± 1.585
8.299LeuGlu: 8.299 ± 0.187
5.187LeuPhe: 5.187 ± 2.065
3.112LeuGly: 3.112 ± 1.585
4.149LeuHis: 4.149 ± 2.691
3.112LeuIle: 3.112 ± 1.585
5.187LeuLys: 5.187 ± 2.065
14.523LeuLeu: 14.523 ± 0.106
2.075LeuMet: 2.075 ± 2.211
2.075LeuAsn: 2.075 ± 2.211
5.187LeuPro: 5.187 ± 2.065
6.224LeuGln: 6.224 ± 3.17
10.373LeuArg: 10.373 ± 4.129
6.224LeuSer: 6.224 ± 2.024
1.037LeuThr: 1.037 ± 0.626
9.336LeuVal: 9.336 ± 2.171
2.075LeuTrp: 2.075 ± 0.48
1.037LeuTyr: 1.037 ± 1.106
0.0LeuXaa: 0.0 ± 0.0
Met
3.112MetAla: 3.112 ± 1.878
1.037MetCys: 1.037 ± 0.626
1.037MetAsp: 1.037 ± 0.626
1.037MetGlu: 1.037 ± 0.626
0.0MetPhe: 0.0 ± 0.0
3.112MetGly: 3.112 ± 1.585
2.075MetHis: 2.075 ± 0.48
2.075MetIle: 2.075 ± 0.48
1.037MetLys: 1.037 ± 0.626
2.075MetLeu: 2.075 ± 1.252
2.075MetMet: 2.075 ± 0.48
0.0MetAsn: 0.0 ± 0.0
2.075MetPro: 2.075 ± 0.48
2.075MetGln: 2.075 ± 2.211
3.112MetArg: 3.112 ± 0.146
2.075MetSer: 2.075 ± 0.48
3.112MetThr: 3.112 ± 1.878
5.187MetVal: 5.187 ± 1.398
0.0MetTrp: 0.0 ± 0.0
1.037MetTyr: 1.037 ± 1.106
0.0MetXaa: 0.0 ± 0.0
Asn
2.075AsnAla: 2.075 ± 1.252
0.0AsnCys: 0.0 ± 0.0
1.037AsnAsp: 1.037 ± 1.106
1.037AsnGlu: 1.037 ± 0.626
0.0AsnPhe: 0.0 ± 0.0
1.037AsnGly: 1.037 ± 0.626
1.037AsnHis: 1.037 ± 0.626
0.0AsnIle: 0.0 ± 0.0
1.037AsnLys: 1.037 ± 0.626
4.149AsnLeu: 4.149 ± 0.959
1.037AsnMet: 1.037 ± 0.626
1.037AsnAsn: 1.037 ± 1.106
0.0AsnPro: 0.0 ± 0.0
0.0AsnGln: 0.0 ± 0.0
2.075AsnArg: 2.075 ± 2.211
2.075AsnSer: 2.075 ± 2.211
2.075AsnThr: 2.075 ± 0.48
0.0AsnVal: 0.0 ± 0.0
2.075AsnTrp: 2.075 ± 2.211
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.037ProAla: 1.037 ± 0.626
1.037ProCys: 1.037 ± 0.626
2.075ProAsp: 2.075 ± 2.211
5.187ProGlu: 5.187 ± 0.333
0.0ProPhe: 0.0 ± 0.0
6.224ProGly: 6.224 ± 3.17
2.075ProHis: 2.075 ± 0.48
2.075ProIle: 2.075 ± 0.48
6.224ProLys: 6.224 ± 2.024
2.075ProLeu: 2.075 ± 1.252
3.112ProMet: 3.112 ± 1.878
0.0ProAsn: 0.0 ± 0.0
2.075ProPro: 2.075 ± 0.48
3.112ProGln: 3.112 ± 1.878
0.0ProArg: 0.0 ± 0.0
5.187ProSer: 5.187 ± 2.065
1.037ProThr: 1.037 ± 0.626
2.075ProVal: 2.075 ± 1.252
0.0ProTrp: 0.0 ± 0.0
1.037ProTyr: 1.037 ± 1.106
0.0ProXaa: 0.0 ± 0.0
Gln
3.112GlnAla: 3.112 ± 0.146
2.075GlnCys: 2.075 ± 1.252
2.075GlnAsp: 2.075 ± 1.252
3.112GlnGlu: 3.112 ± 1.585
1.037GlnPhe: 1.037 ± 0.626
2.075GlnGly: 2.075 ± 1.252
0.0GlnHis: 0.0 ± 0.0
1.037GlnIle: 1.037 ± 1.106
2.075GlnLys: 2.075 ± 1.252
8.299GlnLeu: 8.299 ± 3.65
1.037GlnMet: 1.037 ± 0.626
0.0GlnAsn: 0.0 ± 0.0
3.112GlnPro: 3.112 ± 1.878
3.112GlnGln: 3.112 ± 0.146
4.149GlnArg: 4.149 ± 0.959
1.037GlnSer: 1.037 ± 0.626
1.037GlnThr: 1.037 ± 1.106
5.187GlnVal: 5.187 ± 1.398
0.0GlnTrp: 0.0 ± 0.0
2.075GlnTyr: 2.075 ± 2.211
0.0GlnXaa: 0.0 ± 0.0
Arg
7.261ArgAla: 7.261 ± 0.919
1.037ArgCys: 1.037 ± 0.626
0.0ArgAsp: 0.0 ± 0.0
1.037ArgGlu: 1.037 ± 0.626
3.112ArgPhe: 3.112 ± 1.585
2.075ArgGly: 2.075 ± 1.252
2.075ArgHis: 2.075 ± 1.252
2.075ArgIle: 2.075 ± 1.252
2.075ArgLys: 2.075 ± 1.252
11.411ArgLeu: 11.411 ± 5.235
1.037ArgMet: 1.037 ± 0.626
2.075ArgAsn: 2.075 ± 0.48
4.149ArgPro: 4.149 ± 0.772
5.187ArgGln: 5.187 ± 2.065
9.336ArgArg: 9.336 ± 3.902
8.299ArgSer: 8.299 ± 1.545
3.112ArgThr: 3.112 ± 0.146
7.261ArgVal: 7.261 ± 0.813
1.037ArgTrp: 1.037 ± 1.106
4.149ArgTyr: 4.149 ± 0.959
0.0ArgXaa: 0.0 ± 0.0
Ser
4.149SerAla: 4.149 ± 0.772
2.075SerCys: 2.075 ± 1.252
6.224SerAsp: 6.224 ± 3.756
3.112SerGlu: 3.112 ± 1.878
3.112SerPhe: 3.112 ± 1.585
7.261SerGly: 7.261 ± 0.919
2.075SerHis: 2.075 ± 1.252
2.075SerIle: 2.075 ± 1.252
3.112SerLys: 3.112 ± 1.585
7.261SerLeu: 7.261 ± 4.276
3.112SerMet: 3.112 ± 0.378
1.037SerAsn: 1.037 ± 0.626
4.149SerPro: 4.149 ± 0.959
5.187SerGln: 5.187 ± 3.13
8.299SerArg: 8.299 ± 3.276
14.523SerSer: 14.523 ± 1.837
3.112SerThr: 3.112 ± 1.878
4.149SerVal: 4.149 ± 0.959
2.075SerTrp: 2.075 ± 0.48
1.037SerTyr: 1.037 ± 1.106
0.0SerXaa: 0.0 ± 0.0
Thr
2.075ThrAla: 2.075 ± 1.252
2.075ThrCys: 2.075 ± 1.252
5.187ThrAsp: 5.187 ± 1.398
0.0ThrGlu: 0.0 ± 0.0
1.037ThrPhe: 1.037 ± 1.106
2.075ThrGly: 2.075 ± 0.48
0.0ThrHis: 0.0 ± 0.0
4.149ThrIle: 4.149 ± 0.772
2.075ThrLys: 2.075 ± 1.252
1.037ThrLeu: 1.037 ± 1.106
2.075ThrMet: 2.075 ± 1.252
2.075ThrAsn: 2.075 ± 0.48
1.037ThrPro: 1.037 ± 0.626
1.037ThrGln: 1.037 ± 0.626
1.037ThrArg: 1.037 ± 0.626
1.037ThrSer: 1.037 ± 1.106
1.037ThrThr: 1.037 ± 1.106
7.261ThrVal: 7.261 ± 2.65
2.075ThrTrp: 2.075 ± 1.252
1.037ThrTyr: 1.037 ± 0.626
0.0ThrXaa: 0.0 ± 0.0
Val
11.411ValAla: 11.411 ± 1.691
1.037ValCys: 1.037 ± 0.626
5.187ValAsp: 5.187 ± 2.065
6.224ValGlu: 6.224 ± 1.439
4.149ValPhe: 4.149 ± 0.959
4.149ValGly: 4.149 ± 2.504
0.0ValHis: 0.0 ± 0.0
6.224ValIle: 6.224 ± 2.024
3.112ValLys: 3.112 ± 1.585
4.149ValLeu: 4.149 ± 0.959
1.037ValMet: 1.037 ± 0.35
2.075ValAsn: 2.075 ± 0.48
4.149ValPro: 4.149 ± 2.504
2.075ValGln: 2.075 ± 0.48
5.187ValArg: 5.187 ± 3.13
6.224ValSer: 6.224 ± 0.293
4.149ValThr: 4.149 ± 2.504
11.411ValVal: 11.411 ± 3.423
1.037ValTrp: 1.037 ± 1.106
5.187ValTyr: 5.187 ± 3.13
0.0ValXaa: 0.0 ± 0.0
Trp
1.037TrpAla: 1.037 ± 0.626
1.037TrpCys: 1.037 ± 1.106
3.112TrpAsp: 3.112 ± 1.585
1.037TrpGlu: 1.037 ± 0.626
1.037TrpPhe: 1.037 ± 1.106
1.037TrpGly: 1.037 ± 0.626
1.037TrpHis: 1.037 ± 1.106
2.075TrpIle: 2.075 ± 0.48
2.075TrpLys: 2.075 ± 0.48
2.075TrpLeu: 2.075 ± 2.211
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.075TrpSer: 2.075 ± 0.48
1.037TrpThr: 1.037 ± 1.106
1.037TrpVal: 1.037 ± 1.106
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.037TyrAla: 1.037 ± 1.106
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
2.075TyrGlu: 2.075 ± 0.48
1.037TyrPhe: 1.037 ± 1.106
4.149TyrGly: 4.149 ± 2.504
2.075TyrHis: 2.075 ± 0.48
2.075TyrIle: 2.075 ± 0.48
1.037TyrLys: 1.037 ± 0.626
5.187TyrLeu: 5.187 ± 2.065
1.037TyrMet: 1.037 ± 0.626
0.0TyrAsn: 0.0 ± 0.0
1.037TyrPro: 1.037 ± 1.106
1.037TyrGln: 1.037 ± 0.626
4.149TyrArg: 4.149 ± 4.422
4.149TyrSer: 4.149 ± 0.959
2.075TyrThr: 2.075 ± 1.252
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
1.037TyrTyr: 1.037 ± 1.106
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (965 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski