Amino acid dipepetide frequency for Lachnobacterium bovis DSM 14045

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.176AlaAla: 4.176 ± 0.101	0.832AlaCys: 0.832 ± 0.036	3.452AlaAsp: 3.452 ± 0.069	3.656AlaGlu: 3.656 ± 0.077	2.738AlaPhe: 2.738 ± 0.073	4.147AlaGly: 4.147 ± 0.094	0.841AlaHis: 0.841 ± 0.034	5.506AlaIle: 5.506 ± 0.113	5.618AlaLys: 5.618 ± 0.089	5.495AlaLeu: 5.495 ± 0.09	1.872AlaMet: 1.872 ± 0.058	3.149AlaAsn: 3.149 ± 0.058	1.455AlaPro: 1.455 ± 0.046	1.858AlaGln: 1.858 ± 0.053	2.245AlaArg: 2.245 ± 0.063	3.677AlaSer: 3.677 ± 0.07	3.238AlaThr: 3.238 ± 0.074	4.44AlaVal: 4.44 ± 0.083	0.379AlaTrp: 0.379 ± 0.023	2.259AlaTyr: 2.259 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.823CysAla: 0.823 ± 0.036	0.254CysCys: 0.254 ± 0.02	0.853CysAsp: 0.853 ± 0.038	0.832CysGlu: 0.832 ± 0.029	0.679CysPhe: 0.679 ± 0.032	1.245CysGly: 1.245 ± 0.045	0.23CysHis: 0.23 ± 0.019	1.206CysIle: 1.206 ± 0.043	1.04CysLys: 1.04 ± 0.04	1.012CysLeu: 1.012 ± 0.039	0.351CysMet: 0.351 ± 0.022	0.696CysAsn: 0.696 ± 0.025	0.468CysPro: 0.468 ± 0.027	0.364CysGln: 0.364 ± 0.023	0.453CysArg: 0.453 ± 0.024	0.879CysSer: 0.879 ± 0.036	0.621CysThr: 0.621 ± 0.028	1.004CysVal: 1.004 ± 0.039	0.098CysTrp: 0.098 ± 0.012	0.53CysTyr: 0.53 ± 0.029	0.0CysXaa: 0.0 ± 0.0
Asp	3.61AspAla: 3.61 ± 0.074	0.756AspCys: 0.756 ± 0.032	3.574AspAsp: 3.574 ± 0.095	5.298AspGlu: 5.298 ± 0.083	3.069AspPhe: 3.069 ± 0.068	3.602AspGly: 3.602 ± 0.079	0.627AspHis: 0.627 ± 0.031	5.539AspIle: 5.539 ± 0.1	5.256AspLys: 5.256 ± 0.108	4.771AspLeu: 4.771 ± 0.082	1.662AspMet: 1.662 ± 0.041	3.402AspAsn: 3.402 ± 0.084	1.386AspPro: 1.386 ± 0.042	1.143AspGln: 1.143 ± 0.036	1.932AspArg: 1.932 ± 0.058	3.635AspSer: 3.635 ± 0.07	2.793AspThr: 2.793 ± 0.06	4.304AspVal: 4.304 ± 0.072	0.426AspTrp: 0.426 ± 0.026	3.097AspTyr: 3.097 ± 0.068	0.0AspXaa: 0.0 ± 0.0
Glu	4.255GluAla: 4.255 ± 0.084	0.874GluCys: 0.874 ± 0.037	4.236GluAsp: 4.236 ± 0.074	6.385GluGlu: 6.385 ± 0.101	2.929GluPhe: 2.929 ± 0.071	3.795GluGly: 3.795 ± 0.084	1.129GluHis: 1.129 ± 0.039	6.526GluIle: 6.526 ± 0.123	7.98GluLys: 7.98 ± 0.107	6.486GluLeu: 6.486 ± 0.095	2.128GluMet: 2.128 ± 0.047	5.186GluAsn: 5.186 ± 0.088	1.416GluPro: 1.416 ± 0.049	2.316GluGln: 2.316 ± 0.061	2.595GluArg: 2.595 ± 0.072	3.662GluSer: 3.662 ± 0.075	3.222GluThr: 3.222 ± 0.065	4.845GluVal: 4.845 ± 0.086	0.541GluTrp: 0.541 ± 0.023	3.427GluTyr: 3.427 ± 0.079	0.0GluXaa: 0.0 ± 0.0
Phe	2.719PheAla: 2.719 ± 0.069	0.701PheCys: 0.701 ± 0.03	2.791PheAsp: 2.791 ± 0.069	3.096PheGlu: 3.096 ± 0.07	2.292PhePhe: 2.292 ± 0.064	2.877PheGly: 2.877 ± 0.067	0.621PheHis: 0.621 ± 0.029	3.687PheIle: 3.687 ± 0.065	3.238PheLys: 3.238 ± 0.062	3.846PheLeu: 3.846 ± 0.09	1.244PheMet: 1.244 ± 0.04	2.289PheAsn: 2.289 ± 0.053	1.207PhePro: 1.207 ± 0.042	0.974PheGln: 0.974 ± 0.041	1.375PheArg: 1.375 ± 0.037	3.161PheSer: 3.161 ± 0.07	2.259PheThr: 2.259 ± 0.051	3.308PheVal: 3.308 ± 0.078	0.354PheTrp: 0.354 ± 0.022	1.835PheTyr: 1.835 ± 0.05	0.0PheXaa: 0.0 ± 0.0
Gly	3.94GlyAla: 3.94 ± 0.099	0.981GlyCys: 0.981 ± 0.041	3.177GlyAsp: 3.177 ± 0.061	3.804GlyGlu: 3.804 ± 0.081	2.825GlyPhe: 2.825 ± 0.065	3.825GlyGly: 3.825 ± 0.094	1.07GlyHis: 1.07 ± 0.037	5.92GlyIle: 5.92 ± 0.115	5.822GlyLys: 5.822 ± 0.104	4.959GlyLeu: 4.959 ± 0.102	1.979GlyMet: 1.979 ± 0.053	3.177GlyAsn: 3.177 ± 0.08	1.089GlyPro: 1.089 ± 0.04	1.64GlyGln: 1.64 ± 0.05	2.324GlyArg: 2.324 ± 0.057	3.383GlySer: 3.383 ± 0.061	3.35GlyThr: 3.35 ± 0.073	4.629GlyVal: 4.629 ± 0.081	0.499GlyTrp: 0.499 ± 0.025	3.011GlyTyr: 3.011 ± 0.07	0.0GlyXaa: 0.0 ± 0.0
His	0.726HisAla: 0.726 ± 0.03	0.226HisCys: 0.226 ± 0.015	0.851HisAsp: 0.851 ± 0.038	0.95HisGlu: 0.95 ± 0.044	0.761HisPhe: 0.761 ± 0.03	1.065HisGly: 1.065 ± 0.039	0.337HisHis: 0.337 ± 0.028	1.262HisIle: 1.262 ± 0.039	1.103HisLys: 1.103 ± 0.039	1.201HisLeu: 1.201 ± 0.04	0.411HisMet: 0.411 ± 0.02	0.876HisAsn: 0.876 ± 0.035	0.636HisPro: 0.636 ± 0.029	0.41HisGln: 0.41 ± 0.024	0.523HisArg: 0.523 ± 0.026	0.912HisSer: 0.912 ± 0.031	0.761HisThr: 0.761 ± 0.032	0.963HisVal: 0.963 ± 0.041	0.088HisTrp: 0.088 ± 0.01	0.715HisTyr: 0.715 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	5.548IleAla: 5.548 ± 0.098	1.304IleCys: 1.304 ± 0.044	5.458IleAsp: 5.458 ± 0.085	6.4IleGlu: 6.4 ± 0.095	3.718IlePhe: 3.718 ± 0.085	5.29IleGly: 5.29 ± 0.099	1.224IleHis: 1.224 ± 0.042	7.512IleIle: 7.512 ± 0.142	7.367IleLys: 7.367 ± 0.105	7.347IleLeu: 7.347 ± 0.126	2.272IleMet: 2.272 ± 0.064	4.922IleAsn: 4.922 ± 0.079	2.868IlePro: 2.868 ± 0.058	2.19IleGln: 2.19 ± 0.051	2.978IleArg: 2.978 ± 0.067	5.979IleSer: 5.979 ± 0.098	4.365IleThr: 4.365 ± 0.079	6.128IleVal: 6.128 ± 0.099	0.549IleTrp: 0.549 ± 0.027	3.345IleTyr: 3.345 ± 0.074	0.0IleXaa: 0.0 ± 0.0
Lys	5.22LysAla: 5.22 ± 0.082	0.908LysCys: 0.908 ± 0.041	5.731LysAsp: 5.731 ± 0.104	8.626LysGlu: 8.626 ± 0.122	2.967LysPhe: 2.967 ± 0.062	4.435LysGly: 4.435 ± 0.079	1.215LysHis: 1.215 ± 0.041	7.643LysIle: 7.643 ± 0.102	9.917LysLys: 9.917 ± 0.146	6.842LysLeu: 6.842 ± 0.089	2.607LysMet: 2.607 ± 0.058	6.665LysAsn: 6.665 ± 0.106	1.91LysPro: 1.91 ± 0.052	2.676LysGln: 2.676 ± 0.058	3.209LysArg: 3.209 ± 0.062	4.719LysSer: 4.719 ± 0.087	4.57LysThr: 4.57 ± 0.085	5.916LysVal: 5.916 ± 0.099	0.611LysTrp: 0.611 ± 0.032	4.378LysTyr: 4.378 ± 0.09	0.0LysXaa: 0.0 ± 0.0
Leu	5.45LeuAla: 5.45 ± 0.094	1.287LeuCys: 1.287 ± 0.04	5.317LeuAsp: 5.317 ± 0.088	6.107LeuGlu: 6.107 ± 0.095	3.708LeuPhe: 3.708 ± 0.077	5.245LeuGly: 5.245 ± 0.101	1.165LeuHis: 1.165 ± 0.035	6.554LeuIle: 6.554 ± 0.114	7.442LeuLys: 7.442 ± 0.099	7.333LeuLeu: 7.333 ± 0.122	2.153LeuMet: 2.153 ± 0.049	4.794LeuAsn: 4.794 ± 0.082	2.576LeuPro: 2.576 ± 0.066	2.269LeuGln: 2.269 ± 0.06	2.952LeuArg: 2.952 ± 0.063	6.042LeuSer: 6.042 ± 0.097	4.163LeuThr: 4.163 ± 0.071	5.443LeuVal: 5.443 ± 0.093	0.511LeuTrp: 0.511 ± 0.023	3.226LeuTyr: 3.226 ± 0.07	0.0LeuXaa: 0.0 ± 0.0
Met	1.834MetAla: 1.834 ± 0.049	0.373MetCys: 0.373 ± 0.022	1.633MetAsp: 1.633 ± 0.046	1.866MetGlu: 1.866 ± 0.054	1.121MetPhe: 1.121 ± 0.043	1.715MetGly: 1.715 ± 0.042	0.415MetHis: 0.415 ± 0.024	2.33MetIle: 2.33 ± 0.063	2.591MetLys: 2.591 ± 0.054	2.476MetLeu: 2.476 ± 0.058	0.753MetMet: 0.753 ± 0.033	1.613MetAsn: 1.613 ± 0.043	1.03MetPro: 1.03 ± 0.037	0.92MetGln: 0.92 ± 0.044	1.048MetArg: 1.048 ± 0.034	1.87MetSer: 1.87 ± 0.047	1.469MetThr: 1.469 ± 0.044	1.671MetVal: 1.671 ± 0.052	0.179MetTrp: 0.179 ± 0.015	1.028MetTyr: 1.028 ± 0.035	0.0MetXaa: 0.0 ± 0.0
Asn	3.35AsnAla: 3.35 ± 0.079	0.762AsnCys: 0.762 ± 0.038	3.397AsnAsp: 3.397 ± 0.064	4.225AsnGlu: 4.225 ± 0.08	2.25AsnPhe: 2.25 ± 0.057	3.918AsnGly: 3.918 ± 0.084	0.948AsnHis: 0.948 ± 0.039	5.22AsnIle: 5.22 ± 0.087	5.245AsnLys: 5.245 ± 0.107	4.63AsnLeu: 4.63 ± 0.072	1.6AsnMet: 1.6 ± 0.045	3.993AsnAsn: 3.993 ± 0.088	2.156AsnPro: 2.156 ± 0.064	1.931AsnGln: 1.931 ± 0.057	2.138AsnArg: 2.138 ± 0.059	3.689AsnSer: 3.689 ± 0.078	2.822AsnThr: 2.822 ± 0.056	4.077AsnVal: 4.077 ± 0.076	0.365AsnTrp: 0.365 ± 0.022	2.669AsnTyr: 2.669 ± 0.065	0.0AsnXaa: 0.0 ± 0.0
Pro	1.54ProAla: 1.54 ± 0.042	0.355ProCys: 0.355 ± 0.021	1.764ProAsp: 1.764 ± 0.055	2.26ProGlu: 2.26 ± 0.07	1.325ProPhe: 1.325 ± 0.039	1.573ProGly: 1.573 ± 0.049	0.45ProHis: 0.45 ± 0.026	2.375ProIle: 2.375 ± 0.057	2.143ProLys: 2.143 ± 0.049	2.192ProLeu: 2.192 ± 0.057	0.768ProMet: 0.768 ± 0.037	1.539ProAsn: 1.539 ± 0.038	0.502ProPro: 0.502 ± 0.033	0.887ProGln: 0.887 ± 0.04	0.786ProArg: 0.786 ± 0.033	1.671ProSer: 1.671 ± 0.05	1.455ProThr: 1.455 ± 0.043	2.036ProVal: 2.036 ± 0.051	0.216ProTrp: 0.216 ± 0.019	1.168ProTyr: 1.168 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	1.683GlnAla: 1.683 ± 0.051	0.333GlnCys: 0.333 ± 0.02	1.405GlnAsp: 1.405 ± 0.037	2.152GlnGlu: 2.152 ± 0.056	1.084GlnPhe: 1.084 ± 0.04	1.609GlnGly: 1.609 ± 0.056	0.421GlnHis: 0.421 ± 0.023	2.535GlnIle: 2.535 ± 0.061	2.88GlnLys: 2.88 ± 0.063	2.404GlnLeu: 2.404 ± 0.054	0.949GlnMet: 0.949 ± 0.042	1.745GlnAsn: 1.745 ± 0.054	0.744GlnPro: 0.744 ± 0.042	1.095GlnGln: 1.095 ± 0.072	1.071GlnArg: 1.071 ± 0.04	1.577GlnSer: 1.577 ± 0.045	1.417GlnThr: 1.417 ± 0.045	1.723GlnVal: 1.723 ± 0.049	0.221GlnTrp: 0.221 ± 0.017	1.182GlnTyr: 1.182 ± 0.048	0.0GlnXaa: 0.0 ± 0.0
Arg	2.026ArgAla: 2.026 ± 0.058	0.434ArgCys: 0.434 ± 0.023	1.886ArgAsp: 1.886 ± 0.045	2.886ArgGlu: 2.886 ± 0.071	1.629ArgPhe: 1.629 ± 0.04	1.917ArgGly: 1.917 ± 0.065	0.576ArgHis: 0.576 ± 0.033	3.308ArgIle: 3.308 ± 0.066	3.318ArgLys: 3.318 ± 0.072	2.908ArgLeu: 2.908 ± 0.066	1.114ArgMet: 1.114 ± 0.04	2.085ArgAsn: 2.085 ± 0.062	0.89ArgPro: 0.89 ± 0.034	1.183ArgGln: 1.183 ± 0.037	1.613ArgArg: 1.613 ± 0.053	1.648ArgSer: 1.648 ± 0.042	1.735ArgThr: 1.735 ± 0.049	2.34ArgVal: 2.34 ± 0.059	0.266ArgTrp: 0.266 ± 0.019	1.568ArgTyr: 1.568 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	3.542SerAla: 3.542 ± 0.081	0.775SerCys: 0.775 ± 0.032	3.778SerAsp: 3.778 ± 0.077	4.007SerGlu: 4.007 ± 0.079	2.978SerPhe: 2.978 ± 0.06	4.145SerGly: 4.145 ± 0.075	0.984SerHis: 0.984 ± 0.034	5.235SerIle: 5.235 ± 0.085	5.687SerLys: 5.687 ± 0.094	5.173SerLeu: 5.173 ± 0.086	1.701SerMet: 1.701 ± 0.046	3.621SerAsn: 3.621 ± 0.078	1.454SerPro: 1.454 ± 0.039	1.886SerGln: 1.886 ± 0.054	2.167SerArg: 2.167 ± 0.051	4.246SerSer: 4.246 ± 0.09	3.125SerThr: 3.125 ± 0.063	4.22SerVal: 4.22 ± 0.074	0.415SerTrp: 0.415 ± 0.023	2.732SerTyr: 2.732 ± 0.061	0.0SerXaa: 0.0 ± 0.0
Thr	3.172ThrAla: 3.172 ± 0.072	0.586ThrCys: 0.586 ± 0.03	2.871ThrAsp: 2.871 ± 0.07	2.98ThrGlu: 2.98 ± 0.06	2.235ThrPhe: 2.235 ± 0.056	3.586ThrGly: 3.586 ± 0.071	0.782ThrHis: 0.782 ± 0.032	4.655ThrIle: 4.655 ± 0.082	4.083ThrLys: 4.083 ± 0.081	4.382ThrLeu: 4.382 ± 0.085	1.259ThrMet: 1.259 ± 0.04	2.784ThrAsn: 2.784 ± 0.066	1.759ThrPro: 1.759 ± 0.047	1.433ThrGln: 1.433 ± 0.051	1.774ThrArg: 1.774 ± 0.05	3.214ThrSer: 3.214 ± 0.07	2.945ThrThr: 2.945 ± 0.067	3.738ThrVal: 3.738 ± 0.071	0.343ThrTrp: 0.343 ± 0.02	2.063ThrTyr: 2.063 ± 0.06	0.0ThrXaa: 0.0 ± 0.0
Val	4.646ValAla: 4.646 ± 0.09	1.178ValCys: 1.178 ± 0.043	4.36ValAsp: 4.36 ± 0.076	4.842ValGlu: 4.842 ± 0.091	3.214ValPhe: 3.214 ± 0.067	4.302ValGly: 4.302 ± 0.089	0.929ValHis: 0.929 ± 0.039	5.799ValIle: 5.799 ± 0.106	5.641ValLys: 5.641 ± 0.084	6.136ValLeu: 6.136 ± 0.097	1.832ValMet: 1.832 ± 0.045	3.591ValAsn: 3.591 ± 0.074	2.062ValPro: 2.062 ± 0.055	1.568ValGln: 1.568 ± 0.043	2.241ValArg: 2.241 ± 0.052	4.618ValSer: 4.618 ± 0.075	3.843ValThr: 3.843 ± 0.085	5.357ValVal: 5.357 ± 0.105	0.474ValTrp: 0.474 ± 0.026	2.778ValTyr: 2.778 ± 0.064	0.0ValXaa: 0.0 ± 0.0
Trp	0.398TrpAla: 0.398 ± 0.023	0.098TrpCys: 0.098 ± 0.012	0.434TrpAsp: 0.434 ± 0.026	0.396TrpGlu: 0.396 ± 0.026	0.355TrpPhe: 0.355 ± 0.024	0.482TrpGly: 0.482 ± 0.025	0.118TrpHis: 0.118 ± 0.014	0.59TrpIle: 0.59 ± 0.03	0.625TrpLys: 0.625 ± 0.029	0.609TrpLeu: 0.609 ± 0.026	0.219TrpMet: 0.219 ± 0.018	0.485TrpAsn: 0.485 ± 0.031	0.172TrpPro: 0.172 ± 0.015	0.244TrpGln: 0.244 ± 0.017	0.234TrpArg: 0.234 ± 0.018	0.35TrpSer: 0.35 ± 0.02	0.305TrpThr: 0.305 ± 0.021	0.418TrpVal: 0.418 ± 0.022	0.056TrpTrp: 0.056 ± 0.009	0.319TrpTyr: 0.319 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.373TyrAla: 2.373 ± 0.059	0.623TyrCys: 0.623 ± 0.029	2.915TyrAsp: 2.915 ± 0.083	3.163TyrGlu: 3.163 ± 0.071	1.998TyrPhe: 1.998 ± 0.056	2.63TyrGly: 2.63 ± 0.065	0.693TyrHis: 0.693 ± 0.034	3.362TyrIle: 3.362 ± 0.066	3.77TyrLys: 3.77 ± 0.061	3.536TyrLeu: 3.536 ± 0.066	1.058TyrMet: 1.058 ± 0.039	2.772TyrAsn: 2.772 ± 0.065	1.226TyrPro: 1.226 ± 0.037	1.243TyrGln: 1.243 ± 0.043	1.675TyrArg: 1.675 ± 0.047	2.938TyrSer: 2.938 ± 0.064	2.188TyrThr: 2.188 ± 0.061	2.849TyrVal: 2.849 ± 0.066	0.315TyrTrp: 0.315 ± 0.021	2.136TyrTyr: 2.136 ± 0.07	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2391 proteins (786201 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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