Amino acid dipepetide frequency for Candidatus Chloroploca asiatica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.842AlaAla: 13.842 ± 0.153	1.001AlaCys: 1.001 ± 0.026	5.495AlaAsp: 5.495 ± 0.061	6.891AlaGlu: 6.891 ± 0.093	3.725AlaPhe: 3.725 ± 0.055	8.619AlaGly: 8.619 ± 0.09	2.6AlaHis: 2.6 ± 0.045	5.693AlaIle: 5.693 ± 0.058	1.734AlaLys: 1.734 ± 0.036	14.791AlaLeu: 14.791 ± 0.167	2.741AlaMet: 2.741 ± 0.042	2.878AlaAsn: 2.878 ± 0.052	5.82AlaPro: 5.82 ± 0.079	5.134AlaGln: 5.134 ± 0.066	7.861AlaArg: 7.861 ± 0.079	6.034AlaSer: 6.034 ± 0.069	7.617AlaThr: 7.617 ± 0.099	7.999AlaVal: 7.999 ± 0.089	1.822AlaTrp: 1.822 ± 0.043	3.017AlaTyr: 3.017 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.894CysAla: 0.894 ± 0.026	0.093CysCys: 0.093 ± 0.007	0.415CysAsp: 0.415 ± 0.015	0.383CysGlu: 0.383 ± 0.016	0.271CysPhe: 0.271 ± 0.015	0.838CysGly: 0.838 ± 0.026	0.235CysHis: 0.235 ± 0.014	0.32CysIle: 0.32 ± 0.014	0.121CysLys: 0.121 ± 0.009	0.778CysLeu: 0.778 ± 0.023	0.133CysMet: 0.133 ± 0.011	0.212CysAsn: 0.212 ± 0.012	0.475CysPro: 0.475 ± 0.02	0.32CysGln: 0.32 ± 0.017	0.512CysArg: 0.512 ± 0.019	0.408CysSer: 0.408 ± 0.016	0.464CysThr: 0.464 ± 0.022	0.537CysVal: 0.537 ± 0.018	0.197CysTrp: 0.197 ± 0.025	0.245CysTyr: 0.245 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	5.586AspAla: 5.586 ± 0.075	0.317AspCys: 0.317 ± 0.015	2.981AspAsp: 2.981 ± 0.058	3.705AspGlu: 3.705 ± 0.06	1.531AspPhe: 1.531 ± 0.035	4.547AspGly: 4.547 ± 0.08	1.221AspHis: 1.221 ± 0.028	1.942AspIle: 1.942 ± 0.047	0.812AspLys: 0.812 ± 0.026	6.702AspLeu: 6.702 ± 0.071	0.873AspMet: 0.873 ± 0.023	1.08AspAsn: 1.08 ± 0.039	3.702AspPro: 3.702 ± 0.061	2.319AspGln: 2.319 ± 0.041	3.308AspArg: 3.308 ± 0.047	1.707AspSer: 1.707 ± 0.042	2.358AspThr: 2.358 ± 0.048	3.55AspVal: 3.55 ± 0.049	0.802AspTrp: 0.802 ± 0.024	1.399AspTyr: 1.399 ± 0.029	0.0AspXaa: 0.0 ± 0.0
Glu	7.694GluAla: 7.694 ± 0.099	0.274GluCys: 0.274 ± 0.011	2.292GluAsp: 2.292 ± 0.049	3.258GluGlu: 3.258 ± 0.065	1.476GluPhe: 1.476 ± 0.032	3.962GluGly: 3.962 ± 0.056	1.543GluHis: 1.543 ± 0.037	2.547GluIle: 2.547 ± 0.046	1.08GluLys: 1.08 ± 0.029	6.764GluLeu: 6.764 ± 0.078	1.163GluMet: 1.163 ± 0.032	1.06GluAsn: 1.06 ± 0.029	3.223GluPro: 3.223 ± 0.055	3.366GluGln: 3.366 ± 0.054	5.635GluArg: 5.635 ± 0.08	1.956GluSer: 1.956 ± 0.04	3.02GluThr: 3.02 ± 0.039	4.538GluVal: 4.538 ± 0.056	0.662GluTrp: 0.662 ± 0.019	1.207GluTyr: 1.207 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.166PheAla: 4.166 ± 0.06	0.33PheCys: 0.33 ± 0.014	2.054PheAsp: 2.054 ± 0.038	1.769PheGlu: 1.769 ± 0.036	1.489PhePhe: 1.489 ± 0.037	3.034PheGly: 3.034 ± 0.056	0.655PheHis: 0.655 ± 0.024	1.44PheIle: 1.44 ± 0.034	0.645PheLys: 0.645 ± 0.02	3.328PheLeu: 3.328 ± 0.059	0.558PheMet: 0.558 ± 0.019	1.023PheAsn: 1.023 ± 0.027	1.526PhePro: 1.526 ± 0.031	1.109PheGln: 1.109 ± 0.025	1.923PheArg: 1.923 ± 0.038	1.862PheSer: 1.862 ± 0.04	2.152PheThr: 2.152 ± 0.05	2.841PheVal: 2.841 ± 0.04	0.634PheTrp: 0.634 ± 0.022	1.016PheTyr: 1.016 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	7.726GlyAla: 7.726 ± 0.094	0.757GlyCys: 0.757 ± 0.025	3.804GlyAsp: 3.804 ± 0.068	4.306GlyGlu: 4.306 ± 0.059	2.917GlyPhe: 2.917 ± 0.047	6.387GlyGly: 6.387 ± 0.093	1.633GlyHis: 1.633 ± 0.032	4.076GlyIle: 4.076 ± 0.068	2.1GlyLys: 2.1 ± 0.043	9.255GlyLeu: 9.255 ± 0.096	2.191GlyMet: 2.191 ± 0.045	2.213GlyAsn: 2.213 ± 0.066	3.313GlyPro: 3.313 ± 0.054	3.437GlyGln: 3.437 ± 0.055	5.34GlyArg: 5.34 ± 0.055	4.476GlySer: 4.476 ± 0.082	4.896GlyThr: 4.896 ± 0.077	6.138GlyVal: 6.138 ± 0.079	1.415GlyTrp: 1.415 ± 0.035	2.447GlyTyr: 2.447 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	2.31HisAla: 2.31 ± 0.045	0.22HisCys: 0.22 ± 0.013	1.226HisAsp: 1.226 ± 0.028	1.339HisGlu: 1.339 ± 0.035	0.737HisPhe: 0.737 ± 0.019	1.757HisGly: 1.757 ± 0.041	0.689HisHis: 0.689 ± 0.023	0.968HisIle: 0.968 ± 0.022	0.387HisLys: 0.387 ± 0.016	2.714HisLeu: 2.714 ± 0.048	0.419HisMet: 0.419 ± 0.015	0.555HisAsn: 0.555 ± 0.018	1.674HisPro: 1.674 ± 0.041	1.033HisGln: 1.033 ± 0.028	1.462HisArg: 1.462 ± 0.033	0.903HisSer: 0.903 ± 0.025	1.266HisThr: 1.266 ± 0.034	1.493HisVal: 1.493 ± 0.031	0.362HisTrp: 0.362 ± 0.015	0.717HisTyr: 0.717 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.152IleAla: 6.152 ± 0.07	0.476IleCys: 0.476 ± 0.017	2.774IleAsp: 2.774 ± 0.043	3.333IleGlu: 3.333 ± 0.056	1.978IlePhe: 1.978 ± 0.04	4.332IleGly: 4.332 ± 0.054	0.948IleHis: 0.948 ± 0.024	2.623IleIle: 2.623 ± 0.045	1.134IleLys: 1.134 ± 0.032	4.694IleLeu: 4.694 ± 0.06	0.885IleMet: 0.885 ± 0.025	1.599IleAsn: 1.599 ± 0.036	2.479IlePro: 2.479 ± 0.042	1.594IleGln: 1.594 ± 0.032	2.873IleArg: 2.873 ± 0.048	2.57IleSer: 2.57 ± 0.044	3.231IleThr: 3.231 ± 0.054	4.011IleVal: 4.011 ± 0.051	0.764IleTrp: 0.764 ± 0.026	1.542IleTyr: 1.542 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	2.095LysAla: 2.095 ± 0.047	0.103LysCys: 0.103 ± 0.008	0.817LysAsp: 0.817 ± 0.026	0.979LysGlu: 0.979 ± 0.032	0.446LysPhe: 0.446 ± 0.018	1.405LysGly: 1.405 ± 0.036	0.466LysHis: 0.466 ± 0.016	1.072LysIle: 1.072 ± 0.028	0.519LysLys: 0.519 ± 0.021	2.152LysLeu: 2.152 ± 0.049	0.416LysMet: 0.416 ± 0.017	0.489LysAsn: 0.489 ± 0.018	1.164LysPro: 1.164 ± 0.031	0.919LysGln: 0.919 ± 0.025	1.487LysArg: 1.487 ± 0.034	0.875LysSer: 0.875 ± 0.024	1.156LysThr: 1.156 ± 0.029	1.452LysVal: 1.452 ± 0.038	0.191LysTrp: 0.191 ± 0.012	0.463LysTyr: 0.463 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	15.415LeuAla: 15.415 ± 0.158	0.894LeuCys: 0.894 ± 0.025	6.241LeuAsp: 6.241 ± 0.067	6.023LeuGlu: 6.023 ± 0.088	3.753LeuPhe: 3.753 ± 0.071	9.019LeuGly: 9.019 ± 0.101	2.556LeuHis: 2.556 ± 0.054	6.242LeuIle: 6.242 ± 0.064	2.212LeuLys: 2.212 ± 0.044	13.882LeuLeu: 13.882 ± 0.168	2.345LeuMet: 2.345 ± 0.041	3.012LeuAsn: 3.012 ± 0.047	7.109LeuPro: 7.109 ± 0.073	4.014LeuGln: 4.014 ± 0.048	8.841LeuArg: 8.841 ± 0.096	5.86LeuSer: 5.86 ± 0.063	7.268LeuThr: 7.268 ± 0.082	9.35LeuVal: 9.35 ± 0.084	1.476LeuTrp: 1.476 ± 0.036	2.645LeuTyr: 2.645 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.439MetAla: 2.439 ± 0.039	0.131MetCys: 0.131 ± 0.01	0.739MetAsp: 0.739 ± 0.022	0.871MetGlu: 0.871 ± 0.022	0.541MetPhe: 0.541 ± 0.018	1.464MetGly: 1.464 ± 0.034	0.504MetHis: 0.504 ± 0.016	1.212MetIle: 1.212 ± 0.03	0.497MetLys: 0.497 ± 0.018	2.927MetLeu: 2.927 ± 0.046	0.52MetMet: 0.52 ± 0.021	0.557MetAsn: 0.557 ± 0.021	1.439MetPro: 1.439 ± 0.033	0.996MetGln: 0.996 ± 0.027	1.711MetArg: 1.711 ± 0.029	1.222MetSer: 1.222 ± 0.031	1.427MetThr: 1.427 ± 0.032	1.725MetVal: 1.725 ± 0.032	0.187MetTrp: 0.187 ± 0.011	0.355MetTyr: 0.355 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.762AsnAla: 2.762 ± 0.047	0.19AsnCys: 0.19 ± 0.009	1.456AsnAsp: 1.456 ± 0.041	1.481AsnGlu: 1.481 ± 0.032	0.844AsnPhe: 0.844 ± 0.026	2.282AsnGly: 2.282 ± 0.065	0.539AsnHis: 0.539 ± 0.019	1.152AsnIle: 1.152 ± 0.026	0.475AsnLys: 0.475 ± 0.02	3.131AsnLeu: 3.131 ± 0.049	0.418AsnMet: 0.418 ± 0.017	0.89AsnAsn: 0.89 ± 0.039	1.874AsnPro: 1.874 ± 0.043	1.154AsnGln: 1.154 ± 0.029	1.71AsnArg: 1.71 ± 0.035	1.184AsnSer: 1.184 ± 0.036	1.407AsnThr: 1.407 ± 0.05	1.801AsnVal: 1.801 ± 0.042	0.474AsnTrp: 0.474 ± 0.02	0.742AsnTyr: 0.742 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	6.484ProAla: 6.484 ± 0.081	0.326ProCys: 0.326 ± 0.014	3.71ProAsp: 3.71 ± 0.051	3.977ProGlu: 3.977 ± 0.062	1.99ProPhe: 1.99 ± 0.036	4.825ProGly: 4.825 ± 0.076	1.178ProHis: 1.178 ± 0.029	2.544ProIle: 2.544 ± 0.042	0.83ProLys: 0.83 ± 0.026	6.388ProLeu: 6.388 ± 0.075	1.115ProMet: 1.115 ± 0.027	1.399ProAsn: 1.399 ± 0.035	3.986ProPro: 3.986 ± 0.076	2.132ProGln: 2.132 ± 0.035	3.275ProArg: 3.275 ± 0.049	2.993ProSer: 2.993 ± 0.052	4.142ProThr: 4.142 ± 0.102	4.636ProVal: 4.636 ± 0.065	0.84ProTrp: 0.84 ± 0.023	1.367ProTyr: 1.367 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	5.52GlnAla: 5.52 ± 0.077	0.236GlnCys: 0.236 ± 0.011	1.414GlnAsp: 1.414 ± 0.037	1.882GlnGlu: 1.882 ± 0.038	1.248GlnPhe: 1.248 ± 0.029	3.038GlnGly: 3.038 ± 0.047	1.011GlnHis: 1.011 ± 0.027	2.513GlnIle: 2.513 ± 0.04	0.728GlnLys: 0.728 ± 0.024	4.624GlnLeu: 4.624 ± 0.06	0.965GlnMet: 0.965 ± 0.025	0.836GlnAsn: 0.836 ± 0.024	2.699GlnPro: 2.699 ± 0.045	2.363GlnGln: 2.363 ± 0.051	3.903GlnArg: 3.903 ± 0.056	1.913GlnSer: 1.913 ± 0.036	2.372GlnThr: 2.372 ± 0.041	3.43GlnVal: 3.43 ± 0.053	0.526GlnTrp: 0.526 ± 0.018	0.867GlnTyr: 0.867 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	7.018ArgAla: 7.018 ± 0.075	0.647ArgCys: 0.647 ± 0.028	3.723ArgAsp: 3.723 ± 0.051	4.469ArgGlu: 4.469 ± 0.058	2.67ArgPhe: 2.67 ± 0.042	4.681ArgGly: 4.681 ± 0.063	1.677ArgHis: 1.677 ± 0.037	3.723ArgIle: 3.723 ± 0.056	1.513ArgLys: 1.513 ± 0.039	8.668ArgLeu: 8.668 ± 0.089	1.782ArgMet: 1.782 ± 0.029	1.845ArgAsn: 1.845 ± 0.031	3.688ArgPro: 3.688 ± 0.055	3.347ArgGln: 3.347 ± 0.051	5.66ArgArg: 5.66 ± 0.091	3.637ArgSer: 3.637 ± 0.047	4.044ArgThr: 4.044 ± 0.052	5.039ArgVal: 5.039 ± 0.055	1.287ArgTrp: 1.287 ± 0.028	2.328ArgTyr: 2.328 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	5.076SerAla: 5.076 ± 0.065	0.359SerCys: 0.359 ± 0.013	2.572SerAsp: 2.572 ± 0.051	2.62SerGlu: 2.62 ± 0.044	2.02SerPhe: 2.02 ± 0.038	4.553SerGly: 4.553 ± 0.079	1.02SerHis: 1.02 ± 0.027	2.439SerIle: 2.439 ± 0.042	0.897SerLys: 0.897 ± 0.026	6.008SerLeu: 6.008 ± 0.065	1.089SerMet: 1.089 ± 0.022	1.452SerAsn: 1.452 ± 0.037	3.014SerPro: 3.014 ± 0.053	1.864SerGln: 1.864 ± 0.039	3.166SerArg: 3.166 ± 0.046	2.902SerSer: 2.902 ± 0.056	2.926SerThr: 2.926 ± 0.059	3.578SerVal: 3.578 ± 0.055	0.745SerTrp: 0.745 ± 0.023	1.449SerTyr: 1.449 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	6.398ThrAla: 6.398 ± 0.093	0.551ThrCys: 0.551 ± 0.025	2.781ThrAsp: 2.781 ± 0.062	2.843ThrGlu: 2.843 ± 0.046	2.19ThrPhe: 2.19 ± 0.044	4.963ThrGly: 4.963 ± 0.073	1.221ThrHis: 1.221 ± 0.028	3.619ThrIle: 3.619 ± 0.047	0.856ThrLys: 0.856 ± 0.024	7.733ThrLeu: 7.733 ± 0.085	1.345ThrMet: 1.345 ± 0.029	1.682ThrAsn: 1.682 ± 0.05	4.377ThrPro: 4.377 ± 0.083	1.94ThrGln: 1.94 ± 0.036	3.738ThrArg: 3.738 ± 0.046	3.425ThrSer: 3.425 ± 0.062	4.341ThrThr: 4.341 ± 0.111	4.854ThrVal: 4.854 ± 0.094	0.978ThrTrp: 0.978 ± 0.035	1.644ThrTyr: 1.644 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	9.356ValAla: 9.356 ± 0.092	0.615ValCys: 0.615 ± 0.021	3.636ValAsp: 3.636 ± 0.05	4.405ValGlu: 4.405 ± 0.065	2.294ValPhe: 2.294 ± 0.045	5.741ValGly: 5.741 ± 0.082	1.33ValHis: 1.33 ± 0.027	4.202ValIle: 4.202 ± 0.062	1.426ValLys: 1.426 ± 0.034	8.351ValLeu: 8.351 ± 0.081	1.707ValMet: 1.707 ± 0.031	1.949ValAsn: 1.949 ± 0.037	4.445ValPro: 4.445 ± 0.076	2.927ValGln: 2.927 ± 0.049	5.604ValArg: 5.604 ± 0.072	3.863ValSer: 3.863 ± 0.062	5.061ValThr: 5.061 ± 0.104	6.51ValVal: 6.51 ± 0.07	1.022ValTrp: 1.022 ± 0.034	1.84ValTyr: 1.84 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.407TrpAla: 1.407 ± 0.032	0.138TrpCys: 0.138 ± 0.01	0.65TrpAsp: 0.65 ± 0.027	0.724TrpGlu: 0.724 ± 0.024	0.544TrpPhe: 0.544 ± 0.018	1.078TrpGly: 1.078 ± 0.039	0.451TrpHis: 0.451 ± 0.019	0.703TrpIle: 0.703 ± 0.025	0.289TrpLys: 0.289 ± 0.015	2.098TrpLeu: 2.098 ± 0.049	0.396TrpMet: 0.396 ± 0.017	0.454TrpAsn: 0.454 ± 0.019	0.71TrpPro: 0.71 ± 0.022	0.909TrpGln: 0.909 ± 0.029	1.26TrpArg: 1.26 ± 0.03	0.841TrpSer: 0.841 ± 0.026	0.724TrpThr: 0.724 ± 0.024	0.982TrpVal: 0.982 ± 0.029	0.32TrpTrp: 0.32 ± 0.014	0.447TrpTyr: 0.447 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.974TyrAla: 2.974 ± 0.049	0.196TyrCys: 0.196 ± 0.01	1.661TyrAsp: 1.661 ± 0.045	1.462TyrGlu: 1.462 ± 0.029	0.891TyrPhe: 0.891 ± 0.026	2.304TyrGly: 2.304 ± 0.038	0.752TyrHis: 0.752 ± 0.022	0.965TyrIle: 0.965 ± 0.027	0.409TyrLys: 0.409 ± 0.018	3.171TyrLeu: 3.171 ± 0.049	0.403TyrMet: 0.403 ± 0.017	0.782TyrAsn: 0.782 ± 0.025	1.421TyrPro: 1.421 ± 0.028	1.21TyrGln: 1.21 ± 0.027	2.176TyrArg: 2.176 ± 0.035	1.116TyrSer: 1.116 ± 0.029	1.602TyrThr: 1.602 ± 0.042	1.82TyrVal: 1.82 ± 0.033	0.422TyrTrp: 0.422 ± 0.018	0.765TyrTyr: 0.765 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4456 proteins (1658142 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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