Amino acid dipepetide frequency for Pontibacter lucknowensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.402AlaAla: 7.402 ± 0.118
0.676AlaCys: 0.676 ± 0.025
4.382AlaAsp: 4.382 ± 0.064
5.151AlaGlu: 5.151 ± 0.07
3.694AlaPhe: 3.694 ± 0.055
6.276AlaGly: 6.276 ± 0.086
1.412AlaHis: 1.412 ± 0.036
5.211AlaIle: 5.211 ± 0.064
4.099AlaLys: 4.099 ± 0.062
7.945AlaLeu: 7.945 ± 0.1
2.189AlaMet: 2.189 ± 0.048
3.357AlaAsn: 3.357 ± 0.059
2.951AlaPro: 2.951 ± 0.061
3.445AlaGln: 3.445 ± 0.063
3.511AlaArg: 3.511 ± 0.056
4.768AlaSer: 4.768 ± 0.072
4.598AlaThr: 4.598 ± 0.079
5.342AlaVal: 5.342 ± 0.072
0.798AlaTrp: 0.798 ± 0.028
2.992AlaTyr: 2.992 ± 0.043
0.0AlaXaa: 0.0 ± 0.0
Cys
0.516CysAla: 0.516 ± 0.021
0.121CysCys: 0.121 ± 0.011
0.385CysAsp: 0.385 ± 0.018
0.419CysGlu: 0.419 ± 0.021
0.309CysPhe: 0.309 ± 0.015
0.619CysGly: 0.619 ± 0.035
0.189CysHis: 0.189 ± 0.013
0.443CysIle: 0.443 ± 0.018
0.296CysLys: 0.296 ± 0.016
0.663CysLeu: 0.663 ± 0.023
0.15CysMet: 0.15 ± 0.011
0.307CysAsn: 0.307 ± 0.018
0.356CysPro: 0.356 ± 0.019
0.275CysGln: 0.275 ± 0.016
0.32CysArg: 0.32 ± 0.018
0.491CysSer: 0.491 ± 0.022
0.428CysThr: 0.428 ± 0.027
0.405CysVal: 0.405 ± 0.018
0.065CysTrp: 0.065 ± 0.007
0.254CysTyr: 0.254 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
3.833AspAla: 3.833 ± 0.056
0.348AspCys: 0.348 ± 0.019
2.391AspAsp: 2.391 ± 0.05
3.554AspGlu: 3.554 ± 0.059
2.859AspPhe: 2.859 ± 0.048
3.518AspGly: 3.518 ± 0.071
0.92AspHis: 0.92 ± 0.026
3.393AspIle: 3.393 ± 0.048
3.424AspLys: 3.424 ± 0.057
5.05AspLeu: 5.05 ± 0.067
1.335AspMet: 1.335 ± 0.037
2.473AspAsn: 2.473 ± 0.049
2.108AspPro: 2.108 ± 0.041
1.901AspGln: 1.901 ± 0.04
2.669AspArg: 2.669 ± 0.055
2.68AspSer: 2.68 ± 0.051
2.645AspThr: 2.645 ± 0.046
3.5AspVal: 3.5 ± 0.047
0.745AspTrp: 0.745 ± 0.027
2.419AspTyr: 2.419 ± 0.05
0.0AspXaa: 0.0 ± 0.0
Glu
5.637GluAla: 5.637 ± 0.082
0.283GluCys: 0.283 ± 0.015
3.128GluAsp: 3.128 ± 0.055
5.223GluGlu: 5.223 ± 0.08
2.4GluPhe: 2.4 ± 0.043
4.178GluGly: 4.178 ± 0.064
1.453GluHis: 1.453 ± 0.032
3.893GluIle: 3.893 ± 0.057
4.284GluLys: 4.284 ± 0.064
6.828GluLeu: 6.828 ± 0.095
1.658GluMet: 1.658 ± 0.037
3.05GluAsn: 3.05 ± 0.056
2.091GluPro: 2.091 ± 0.037
3.645GluGln: 3.645 ± 0.057
3.599GluArg: 3.599 ± 0.06
3.048GluSer: 3.048 ± 0.052
3.161GluThr: 3.161 ± 0.049
4.853GluVal: 4.853 ± 0.066
0.628GluTrp: 0.628 ± 0.023
2.11GluTyr: 2.11 ± 0.043
0.0GluXaa: 0.0 ± 0.0
Phe
3.373PheAla: 3.373 ± 0.051
0.353PheCys: 0.353 ± 0.016
2.702PheAsp: 2.702 ± 0.05
2.831PheGlu: 2.831 ± 0.049
2.199PhePhe: 2.199 ± 0.051
3.269PheGly: 3.269 ± 0.05
0.823PheHis: 0.823 ± 0.025
2.683PheIle: 2.683 ± 0.058
2.382PheLys: 2.382 ± 0.049
4.184PheLeu: 4.184 ± 0.081
1.198PheMet: 1.198 ± 0.032
2.222PheAsn: 2.222 ± 0.043
1.572PhePro: 1.572 ± 0.037
1.449PheGln: 1.449 ± 0.036
2.283PheArg: 2.283 ± 0.045
3.218PheSer: 3.218 ± 0.053
2.77PheThr: 2.77 ± 0.051
3.109PheVal: 3.109 ± 0.051
0.588PheTrp: 0.588 ± 0.023
1.821PheTyr: 1.821 ± 0.038
0.0PheXaa: 0.0 ± 0.0
Gly
5.151GlyAla: 5.151 ± 0.072
0.615GlyCys: 0.615 ± 0.041
3.284GlyAsp: 3.284 ± 0.06
4.078GlyGlu: 4.078 ± 0.068
3.437GlyPhe: 3.437 ± 0.049
5.24GlyGly: 5.24 ± 0.103
1.372GlyHis: 1.372 ± 0.033
5.326GlyIle: 5.326 ± 0.068
4.546GlyLys: 4.546 ± 0.064
6.42GlyLeu: 6.42 ± 0.081
2.055GlyMet: 2.055 ± 0.051
3.365GlyAsn: 3.365 ± 0.067
1.888GlyPro: 1.888 ± 0.054
2.72GlyGln: 2.72 ± 0.052
3.306GlyArg: 3.306 ± 0.057
4.272GlySer: 4.272 ± 0.09
4.423GlyThr: 4.423 ± 0.108
4.597GlyVal: 4.597 ± 0.061
0.86GlyTrp: 0.86 ± 0.025
3.051GlyTyr: 3.051 ± 0.049
0.0GlyXaa: 0.0 ± 0.0
His
1.358HisAla: 1.358 ± 0.034
0.168HisCys: 0.168 ± 0.013
1.026HisAsp: 1.026 ± 0.029
1.218HisGlu: 1.218 ± 0.033
1.109HisPhe: 1.109 ± 0.024
1.397HisGly: 1.397 ± 0.036
0.615HisHis: 0.615 ± 0.026
1.316HisIle: 1.316 ± 0.036
1.062HisLys: 1.062 ± 0.027
2.09HisLeu: 2.09 ± 0.047
0.499HisMet: 0.499 ± 0.019
0.906HisAsn: 0.906 ± 0.024
1.093HisPro: 1.093 ± 0.034
0.844HisGln: 0.844 ± 0.028
1.04HisArg: 1.04 ± 0.03
1.118HisSer: 1.118 ± 0.029
1.309HisThr: 1.309 ± 0.032
1.209HisVal: 1.209 ± 0.032
0.243HisTrp: 0.243 ± 0.015
0.983HisTyr: 0.983 ± 0.029
0.0HisXaa: 0.0 ± 0.0
Ile
5.358IleAla: 5.358 ± 0.068
0.497IleCys: 0.497 ± 0.024
3.452IleAsp: 3.452 ± 0.051
3.867IleGlu: 3.867 ± 0.057
2.536IlePhe: 2.536 ± 0.051
4.646IleGly: 4.646 ± 0.065
1.088IleHis: 1.088 ± 0.031
3.79IleIle: 3.79 ± 0.072
3.45IleLys: 3.45 ± 0.063
5.509IleLeu: 5.509 ± 0.086
1.345IleMet: 1.345 ± 0.036
2.903IleAsn: 2.903 ± 0.049
3.078IlePro: 3.078 ± 0.056
2.106IleGln: 2.106 ± 0.043
3.171IleArg: 3.171 ± 0.047
4.17IleSer: 4.17 ± 0.062
3.896IleThr: 3.896 ± 0.072
4.046IleVal: 4.046 ± 0.067
0.58IleTrp: 0.58 ± 0.019
2.086IleTyr: 2.086 ± 0.039
0.0IleXaa: 0.0 ± 0.0
Lys
4.845LysAla: 4.845 ± 0.075
0.258LysCys: 0.258 ± 0.011
3.051LysAsp: 3.051 ± 0.055
4.301LysGlu: 4.301 ± 0.075
1.883LysPhe: 1.883 ± 0.034
3.916LysGly: 3.916 ± 0.057
1.225LysHis: 1.225 ± 0.03
3.228LysIle: 3.228 ± 0.052
3.877LysLys: 3.877 ± 0.078
5.706LysLeu: 5.706 ± 0.081
1.523LysMet: 1.523 ± 0.039
2.549LysAsn: 2.549 ± 0.048
2.611LysPro: 2.611 ± 0.049
2.551LysGln: 2.551 ± 0.05
2.8LysArg: 2.8 ± 0.044
3.181LysSer: 3.181 ± 0.043
3.093LysThr: 3.093 ± 0.05
4.182LysVal: 4.182 ± 0.059
0.595LysTrp: 0.595 ± 0.019
2.07LysTyr: 2.07 ± 0.042
0.0LysXaa: 0.0 ± 0.0
Leu
7.941LeuAla: 7.941 ± 0.091
0.734LeuCys: 0.734 ± 0.028
4.906LeuAsp: 4.906 ± 0.077
6.129LeuGlu: 6.129 ± 0.083
4.408LeuPhe: 4.408 ± 0.074
6.381LeuGly: 6.381 ± 0.093
2.23LeuHis: 2.23 ± 0.047
5.709LeuIle: 5.709 ± 0.084
5.693LeuLys: 5.693 ± 0.074
11.015LeuLeu: 11.015 ± 0.188
2.444LeuMet: 2.444 ± 0.049
4.611LeuAsn: 4.611 ± 0.062
4.454LeuPro: 4.454 ± 0.06
5.074LeuGln: 5.074 ± 0.073
5.08LeuArg: 5.08 ± 0.068
6.594LeuSer: 6.594 ± 0.09
5.596LeuThr: 5.596 ± 0.069
6.474LeuVal: 6.474 ± 0.088
0.966LeuTrp: 0.966 ± 0.026
3.758LeuTyr: 3.758 ± 0.063
0.0LeuXaa: 0.0 ± 0.0
Met
2.413MetAla: 2.413 ± 0.048
0.105MetCys: 0.105 ± 0.009
1.171MetAsp: 1.171 ± 0.031
1.629MetGlu: 1.629 ± 0.036
0.87MetPhe: 0.87 ± 0.029
1.789MetGly: 1.789 ± 0.04
0.542MetHis: 0.542 ± 0.019
1.333MetIle: 1.333 ± 0.037
1.773MetLys: 1.773 ± 0.041
2.774MetLeu: 2.774 ± 0.052
0.675MetMet: 0.675 ± 0.026
1.159MetAsn: 1.159 ± 0.03
1.223MetPro: 1.223 ± 0.033
1.27MetGln: 1.27 ± 0.029
1.32MetArg: 1.32 ± 0.034
1.35MetSer: 1.35 ± 0.039
1.313MetThr: 1.313 ± 0.032
1.664MetVal: 1.664 ± 0.044
0.183MetTrp: 0.183 ± 0.012
0.688MetTyr: 0.688 ± 0.025
0.0MetXaa: 0.0 ± 0.0
Asn
3.344AsnAla: 3.344 ± 0.05
0.309AsnCys: 0.309 ± 0.019
2.128AsnAsp: 2.128 ± 0.04
2.594AsnGlu: 2.594 ± 0.052
2.159AsnPhe: 2.159 ± 0.048
3.294AsnGly: 3.294 ± 0.093
0.848AsnHis: 0.848 ± 0.026
3.042AsnIle: 3.042 ± 0.053
2.611AsnLys: 2.611 ± 0.045
4.506AsnLeu: 4.506 ± 0.069
1.215AsnMet: 1.215 ± 0.029
2.28AsnAsn: 2.28 ± 0.045
2.56AsnPro: 2.56 ± 0.048
1.783AsnGln: 1.783 ± 0.04
2.375AsnArg: 2.375 ± 0.046
2.744AsnSer: 2.744 ± 0.058
2.777AsnThr: 2.777 ± 0.052
2.943AsnVal: 2.943 ± 0.052
0.639AsnTrp: 0.639 ± 0.025
2.078AsnTyr: 2.078 ± 0.047
0.0AsnXaa: 0.0 ± 0.0
Pro
3.883ProAla: 3.883 ± 0.069
0.229ProCys: 0.229 ± 0.012
2.876ProAsp: 2.876 ± 0.053
3.545ProGlu: 3.545 ± 0.056
1.828ProPhe: 1.828 ± 0.042
2.799ProGly: 2.799 ± 0.054
0.889ProHis: 0.889 ± 0.028
2.325ProIle: 2.325 ± 0.046
2.043ProLys: 2.043 ± 0.04
3.583ProLeu: 3.583 ± 0.055
0.905ProMet: 0.905 ± 0.024
1.912ProAsn: 1.912 ± 0.048
1.153ProPro: 1.153 ± 0.043
1.59ProGln: 1.59 ± 0.038
1.527ProArg: 1.527 ± 0.036
2.21ProSer: 2.21 ± 0.046
2.225ProThr: 2.225 ± 0.05
3.447ProVal: 3.447 ± 0.056
0.403ProTrp: 0.403 ± 0.018
1.668ProTyr: 1.668 ± 0.04
0.0ProXaa: 0.0 ± 0.0
Gln
3.534GlnAla: 3.534 ± 0.057
0.19GlnCys: 0.19 ± 0.012
2.06GlnAsp: 2.06 ± 0.04
3.213GlnGlu: 3.213 ± 0.056
1.506GlnPhe: 1.506 ± 0.03
2.633GlnGly: 2.633 ± 0.051
1.186GlnHis: 1.186 ± 0.029
2.226GlnIle: 2.226 ± 0.042
2.449GlnLys: 2.449 ± 0.053
4.7GlnLeu: 4.7 ± 0.071
1.0GlnMet: 1.0 ± 0.03
1.968GlnAsn: 1.968 ± 0.038
1.952GlnPro: 1.952 ± 0.04
2.778GlnGln: 2.778 ± 0.063
2.197GlnArg: 2.197 ± 0.048
2.093GlnSer: 2.093 ± 0.04
2.117GlnThr: 2.117 ± 0.04
3.373GlnVal: 3.373 ± 0.054
0.42GlnTrp: 0.42 ± 0.019
1.483GlnTyr: 1.483 ± 0.032
0.0GlnXaa: 0.0 ± 0.0
Arg
3.153ArgAla: 3.153 ± 0.055
0.267ArgCys: 0.267 ± 0.016
2.516ArgAsp: 2.516 ± 0.053
3.37ArgGlu: 3.37 ± 0.051
2.432ArgPhe: 2.432 ± 0.045
2.754ArgGly: 2.754 ± 0.052
1.197ArgHis: 1.197 ± 0.029
3.297ArgIle: 3.297 ± 0.047
2.946ArgLys: 2.946 ± 0.055
4.98ArgLeu: 4.98 ± 0.07
1.451ArgMet: 1.451 ± 0.033
2.511ArgAsn: 2.511 ± 0.042
1.864ArgPro: 1.864 ± 0.044
2.429ArgGln: 2.429 ± 0.049
2.452ArgArg: 2.452 ± 0.058
2.767ArgSer: 2.767 ± 0.05
2.561ArgThr: 2.561 ± 0.046
3.257ArgVal: 3.257 ± 0.051
0.569ArgTrp: 0.569 ± 0.021
2.321ArgTyr: 2.321 ± 0.048
0.0ArgXaa: 0.0 ± 0.0
Ser
4.364SerAla: 4.364 ± 0.062
0.574SerCys: 0.574 ± 0.024
3.017SerAsp: 3.017 ± 0.049
3.489SerGlu: 3.489 ± 0.056
3.112SerPhe: 3.112 ± 0.05
4.729SerGly: 4.729 ± 0.081
1.186SerHis: 1.186 ± 0.033
3.809SerIle: 3.809 ± 0.062
3.206SerLys: 3.206 ± 0.054
5.959SerLeu: 5.959 ± 0.085
1.49SerMet: 1.49 ± 0.035
2.655SerAsn: 2.655 ± 0.053
2.496SerPro: 2.496 ± 0.047
2.12SerGln: 2.12 ± 0.048
2.861SerArg: 2.861 ± 0.05
3.846SerSer: 3.846 ± 0.079
3.506SerThr: 3.506 ± 0.058
3.931SerVal: 3.931 ± 0.06
0.685SerTrp: 0.685 ± 0.025
2.515SerTyr: 2.515 ± 0.05
0.0SerXaa: 0.0 ± 0.0
Thr
4.906ThrAla: 4.906 ± 0.093
0.375ThrCys: 0.375 ± 0.028
3.135ThrAsp: 3.135 ± 0.057
3.348ThrGlu: 3.348 ± 0.054
2.752ThrPhe: 2.752 ± 0.057
4.73ThrGly: 4.73 ± 0.111
1.068ThrHis: 1.068 ± 0.033
3.758ThrIle: 3.758 ± 0.067
2.575ThrLys: 2.575 ± 0.048
5.724ThrLeu: 5.724 ± 0.076
1.171ThrMet: 1.171 ± 0.029
2.346ThrAsn: 2.346 ± 0.051
2.814ThrPro: 2.814 ± 0.05
1.991ThrGln: 1.991 ± 0.045
2.363ThrArg: 2.363 ± 0.047
3.506ThrSer: 3.506 ± 0.065
3.529ThrThr: 3.529 ± 0.115
4.226ThrVal: 4.226 ± 0.104
0.667ThrTrp: 0.667 ± 0.029
2.477ThrTyr: 2.477 ± 0.061
0.0ThrXaa: 0.0 ± 0.0
Val
5.65ValAla: 5.65 ± 0.069
0.527ValCys: 0.527 ± 0.027
3.388ValAsp: 3.388 ± 0.048
4.269ValGlu: 4.269 ± 0.066
3.008ValPhe: 3.008 ± 0.049
4.406ValGly: 4.406 ± 0.067
1.267ValHis: 1.267 ± 0.032
4.117ValIle: 4.117 ± 0.072
3.856ValLys: 3.856 ± 0.058
7.215ValLeu: 7.215 ± 0.082
1.734ValMet: 1.734 ± 0.038
3.084ValAsn: 3.084 ± 0.054
2.861ValPro: 2.861 ± 0.052
2.948ValGln: 2.948 ± 0.044
3.398ValArg: 3.398 ± 0.049
4.341ValSer: 4.341 ± 0.072
4.005ValThr: 4.005 ± 0.106
5.116ValVal: 5.116 ± 0.074
0.786ValTrp: 0.786 ± 0.027
2.708ValTyr: 2.708 ± 0.051
0.0ValXaa: 0.0 ± 0.0
Trp
0.76TrpAla: 0.76 ± 0.027
0.081TrpCys: 0.081 ± 0.008
0.579TrpAsp: 0.579 ± 0.022
0.678TrpGlu: 0.678 ± 0.026
0.498TrpPhe: 0.498 ± 0.02
0.702TrpGly: 0.702 ± 0.019
0.265TrpHis: 0.265 ± 0.013
0.542TrpIle: 0.542 ± 0.019
0.626TrpLys: 0.626 ± 0.025
1.293TrpLeu: 1.293 ± 0.037
0.34TrpMet: 0.34 ± 0.016
0.517TrpAsn: 0.517 ± 0.021
0.318TrpPro: 0.318 ± 0.015
0.583TrpGln: 0.583 ± 0.021
0.622TrpArg: 0.622 ± 0.021
0.638TrpSer: 0.638 ± 0.024
0.577TrpThr: 0.577 ± 0.023
0.808TrpVal: 0.808 ± 0.023
0.159TrpTrp: 0.159 ± 0.013
0.427TrpTyr: 0.427 ± 0.018
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.778TyrAla: 2.778 ± 0.046
0.302TyrCys: 0.302 ± 0.019
2.19TyrAsp: 2.19 ± 0.044
2.247TyrGlu: 2.247 ± 0.043
2.026TyrPhe: 2.026 ± 0.041
2.73TyrGly: 2.73 ± 0.054
0.828TyrHis: 0.828 ± 0.026
2.131TyrIle: 2.131 ± 0.036
2.246TyrLys: 2.246 ± 0.049
4.055TyrLeu: 4.055 ± 0.072
0.867TyrMet: 0.867 ± 0.025
2.053TyrAsn: 2.053 ± 0.043
1.597TyrPro: 1.597 ± 0.037
1.575TyrGln: 1.575 ± 0.031
2.2TyrArg: 2.2 ± 0.041
2.518TyrSer: 2.518 ± 0.048
2.931TyrThr: 2.931 ± 0.07
2.2TyrVal: 2.2 ± 0.044
0.434TyrTrp: 0.434 ± 0.019
1.715TyrTyr: 1.715 ± 0.041
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3901 proteins (1318896 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski