Amino acid dipepetide frequency for Groundnut rosette virus (strain MC1) (GRV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.962AlaAla: 14.962 ± 1.502
1.213AlaCys: 1.213 ± 0.463
1.213AlaAsp: 1.213 ± 0.439
6.874AlaGlu: 6.874 ± 1.271
1.213AlaPhe: 1.213 ± 0.421
6.874AlaGly: 6.874 ± 0.963
2.022AlaHis: 2.022 ± 0.669
3.235AlaIle: 3.235 ± 0.889
6.47AlaLys: 6.47 ± 1.496
10.109AlaLeu: 10.109 ± 0.958
2.426AlaMet: 2.426 ± 0.926
2.831AlaAsn: 2.831 ± 0.367
9.3AlaPro: 9.3 ± 0.968
5.257AlaGln: 5.257 ± 1.149
6.066AlaArg: 6.066 ± 1.199
5.257AlaSer: 5.257 ± 1.511
6.47AlaThr: 6.47 ± 1.567
5.661AlaVal: 5.661 ± 1.303
1.213AlaTrp: 1.213 ± 0.463
2.022AlaTyr: 2.022 ± 0.584
0.0AlaXaa: 0.0 ± 0.0
Cys
1.617CysAla: 1.617 ± 0.984
0.809CysCys: 0.809 ± 0.304
2.022CysAsp: 2.022 ± 0.584
1.213CysGlu: 1.213 ± 0.463
0.404CysPhe: 0.404 ± 0.536
3.235CysGly: 3.235 ± 0.485
0.0CysHis: 0.0 ± 0.0
2.022CysIle: 2.022 ± 0.584
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
1.617CysMet: 1.617 ± 0.576
0.404CysAsn: 0.404 ± 0.581
1.213CysPro: 1.213 ± 0.463
2.022CysGln: 2.022 ± 0.584
2.831CysArg: 2.831 ± 0.715
0.0CysSer: 0.0 ± 0.0
0.809CysThr: 0.809 ± 0.304
4.044CysVal: 4.044 ± 0.703
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.066AspAla: 6.066 ± 0.593
4.448AspCys: 4.448 ± 1.21
3.235AspAsp: 3.235 ± 0.512
2.022AspGlu: 2.022 ± 0.584
0.809AspPhe: 0.809 ± 0.304
4.852AspGly: 4.852 ± 1.101
0.0AspHis: 0.0 ± 0.0
1.617AspIle: 1.617 ± 0.522
1.617AspLys: 1.617 ± 0.662
4.448AspLeu: 4.448 ± 0.816
0.809AspMet: 0.809 ± 0.304
0.809AspAsn: 0.809 ± 0.304
2.426AspPro: 2.426 ± 0.879
2.022AspGln: 2.022 ± 0.502
0.0AspArg: 0.0 ± 0.0
1.213AspSer: 1.213 ± 0.421
1.617AspThr: 1.617 ± 0.662
1.617AspVal: 1.617 ± 0.608
2.426AspTrp: 2.426 ± 0.926
1.617AspTyr: 1.617 ± 0.608
0.0AspXaa: 0.0 ± 0.0
Glu
4.852GluAla: 4.852 ± 1.664
2.831GluCys: 2.831 ± 0.807
4.852GluAsp: 4.852 ± 1.177
3.639GluGlu: 3.639 ± 0.748
0.809GluPhe: 0.809 ± 0.304
6.066GluGly: 6.066 ± 1.625
0.809GluHis: 0.809 ± 0.304
3.639GluIle: 3.639 ± 0.703
2.022GluLys: 2.022 ± 0.502
4.852GluLeu: 4.852 ± 1.178
0.404GluMet: 0.404 ± 0.536
2.022GluAsn: 2.022 ± 0.584
3.235GluPro: 3.235 ± 0.512
2.831GluGln: 2.831 ± 0.807
2.022GluArg: 2.022 ± 0.483
0.809GluSer: 0.809 ± 0.886
2.022GluThr: 2.022 ± 0.502
8.492GluVal: 8.492 ± 1.646
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.831PheAla: 2.831 ± 0.946
0.809PheCys: 0.809 ± 0.304
2.022PheAsp: 2.022 ± 0.483
0.809PheGlu: 0.809 ± 0.304
0.0PhePhe: 0.0 ± 0.0
2.022PheGly: 2.022 ± 0.584
0.0PheHis: 0.0 ± 0.0
1.617PheIle: 1.617 ± 0.608
0.0PheLys: 0.0 ± 0.0
1.617PheLeu: 1.617 ± 0.608
0.0PheMet: 0.0 ± 0.442
2.831PheAsn: 2.831 ± 0.677
0.404PhePro: 0.404 ± 0.536
2.022PheGln: 2.022 ± 0.584
1.617PheArg: 1.617 ± 0.608
0.404PheSer: 0.404 ± 0.536
3.639PheThr: 3.639 ± 0.669
1.617PheVal: 1.617 ± 0.608
0.0PheTrp: 0.0 ± 0.0
1.213PheTyr: 1.213 ± 0.421
0.0PheXaa: 0.0 ± 0.0
Gly
11.322GlyAla: 11.322 ± 1.886
3.235GlyCys: 3.235 ± 0.485
4.448GlyAsp: 4.448 ± 0.965
7.279GlyGlu: 7.279 ± 1.787
2.831GlyPhe: 2.831 ± 0.677
6.47GlyGly: 6.47 ± 2.055
0.404GlyHis: 0.404 ± 0.581
4.448GlyIle: 4.448 ± 1.21
4.044GlyLys: 4.044 ± 1.841
3.235GlyLeu: 3.235 ± 0.547
3.235GlyMet: 3.235 ± 0.547
4.448GlyAsn: 4.448 ± 1.458
2.426GlyPro: 2.426 ± 1.535
1.213GlyGln: 1.213 ± 1.743
4.448GlyArg: 4.448 ± 1.265
4.044GlySer: 4.044 ± 0.594
2.022GlyThr: 2.022 ± 0.584
6.47GlyVal: 6.47 ± 1.064
1.213GlyTrp: 1.213 ± 0.463
0.809GlyTyr: 0.809 ± 0.304
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.404HisAsp: 0.404 ± 0.536
1.617HisGlu: 1.617 ± 0.608
0.0HisPhe: 0.0 ± 0.0
2.022HisGly: 2.022 ± 0.584
0.404HisHis: 0.404 ± 0.581
2.426HisIle: 2.426 ± 0.392
0.404HisLys: 0.404 ± 0.581
3.639HisLeu: 3.639 ± 1.071
1.213HisMet: 1.213 ± 0.463
2.022HisAsn: 2.022 ± 0.502
1.617HisPro: 1.617 ± 0.522
0.0HisGln: 0.0 ± 0.0
1.213HisArg: 1.213 ± 1.345
0.404HisSer: 0.404 ± 0.581
0.404HisThr: 0.404 ± 0.581
1.617HisVal: 1.617 ± 0.662
0.404HisTrp: 0.404 ± 0.536
2.831HisTyr: 2.831 ± 0.807
0.0HisXaa: 0.0 ± 0.0
Ile
3.639IleAla: 3.639 ± 0.748
0.404IleCys: 0.404 ± 0.536
2.022IleAsp: 2.022 ± 0.483
1.617IleGlu: 1.617 ± 0.608
0.809IlePhe: 0.809 ± 0.304
2.022IleGly: 2.022 ± 0.584
1.617IleHis: 1.617 ± 0.48
0.0IleIle: 0.0 ± 0.0
4.044IleLys: 4.044 ± 0.703
3.235IleLeu: 3.235 ± 1.009
2.831IleMet: 2.831 ± 0.367
1.213IleAsn: 1.213 ± 0.439
4.044IlePro: 4.044 ± 0.652
1.213IleGln: 1.213 ± 0.439
1.617IleArg: 1.617 ± 0.522
1.617IleSer: 1.617 ± 0.915
2.022IleThr: 2.022 ± 0.584
3.235IleVal: 3.235 ± 0.512
2.426IleTrp: 2.426 ± 0.926
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.639LysAla: 3.639 ± 0.669
0.0LysCys: 0.0 ± 0.0
2.831LysAsp: 2.831 ± 0.988
0.404LysGlu: 0.404 ± 0.536
0.809LysPhe: 0.809 ± 0.304
3.235LysGly: 3.235 ± 0.872
0.0LysHis: 0.0 ± 0.0
1.213LysIle: 1.213 ± 0.421
2.022LysLys: 2.022 ± 0.483
4.448LysLeu: 4.448 ± 1.352
0.809LysMet: 0.809 ± 0.304
0.809LysAsn: 0.809 ± 0.304
4.448LysPro: 4.448 ± 0.719
1.617LysGln: 1.617 ± 0.608
1.213LysArg: 1.213 ± 0.439
4.448LysSer: 4.448 ± 0.965
2.022LysThr: 2.022 ± 0.483
3.639LysVal: 3.639 ± 0.978
2.022LysTrp: 2.022 ± 0.483
2.831LysTyr: 2.831 ± 0.677
0.0LysXaa: 0.0 ± 0.0
Leu
6.47LeuAla: 6.47 ± 1.389
1.213LeuCys: 1.213 ± 0.463
2.831LeuAsp: 2.831 ± 0.677
5.661LeuGlu: 5.661 ± 0.86
0.404LeuPhe: 0.404 ± 0.581
8.896LeuGly: 8.896 ± 1.757
2.022LeuHis: 2.022 ± 0.669
0.0LeuIle: 0.0 ± 0.0
2.022LeuLys: 2.022 ± 0.584
8.492LeuLeu: 8.492 ± 2.124
5.661LeuMet: 5.661 ± 1.082
2.022LeuAsn: 2.022 ± 1.122
5.661LeuPro: 5.661 ± 0.943
2.831LeuGln: 2.831 ± 0.776
10.514LeuArg: 10.514 ± 1.216
8.492LeuSer: 8.492 ± 0.948
0.809LeuThr: 0.809 ± 1.072
2.022LeuVal: 2.022 ± 0.483
1.617LeuTrp: 1.617 ± 0.608
3.235LeuTyr: 3.235 ± 0.876
0.0LeuXaa: 0.0 ± 0.0
Met
2.831MetAla: 2.831 ± 0.776
0.0MetCys: 0.0 ± 0.0
4.852MetAsp: 4.852 ± 0.495
1.213MetGlu: 1.213 ± 0.463
2.022MetPhe: 2.022 ± 0.584
0.809MetGly: 0.809 ± 0.304
0.0MetHis: 0.0 ± 0.0
1.213MetIle: 1.213 ± 0.463
0.809MetLys: 0.809 ± 0.304
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.213MetAsn: 1.213 ± 0.463
1.213MetPro: 1.213 ± 0.421
2.022MetGln: 2.022 ± 0.502
2.022MetArg: 2.022 ± 0.502
4.448MetSer: 4.448 ± 0.251
2.022MetThr: 2.022 ± 0.584
2.022MetVal: 2.022 ± 0.502
1.617MetTrp: 1.617 ± 0.48
0.809MetTyr: 0.809 ± 0.304
0.0MetXaa: 0.0 ± 0.0
Asn
5.661AsnAla: 5.661 ± 1.236
0.809AsnCys: 0.809 ± 0.304
0.809AsnAsp: 0.809 ± 0.304
3.235AsnGlu: 3.235 ± 0.485
2.022AsnPhe: 2.022 ± 0.584
4.044AsnGly: 4.044 ± 0.745
1.617AsnHis: 1.617 ± 0.608
0.0AsnIle: 0.0 ± 0.0
0.809AsnLys: 0.809 ± 1.162
2.426AsnLeu: 2.426 ± 0.843
0.0AsnMet: 0.0 ± 0.0
2.426AsnAsn: 2.426 ± 0.912
3.235AsnPro: 3.235 ± 0.512
0.809AsnGln: 0.809 ± 0.304
3.235AsnArg: 3.235 ± 1.009
2.426AsnSer: 2.426 ± 0.526
0.809AsnThr: 0.809 ± 0.886
1.213AsnVal: 1.213 ± 0.439
0.809AsnTrp: 0.809 ± 0.304
0.404AsnTyr: 0.404 ± 0.536
0.0AsnXaa: 0.0 ± 0.0
Pro
8.492ProAla: 8.492 ± 2.431
2.022ProCys: 2.022 ± 0.584
1.213ProAsp: 1.213 ± 0.421
0.404ProGlu: 0.404 ± 0.536
0.404ProPhe: 0.404 ± 0.536
4.044ProGly: 4.044 ± 0.51
3.639ProHis: 3.639 ± 1.344
0.404ProIle: 0.404 ± 0.536
1.213ProLys: 1.213 ± 0.439
6.066ProLeu: 6.066 ± 1.449
1.213ProMet: 1.213 ± 0.463
0.809ProAsn: 0.809 ± 0.886
5.661ProPro: 5.661 ± 1.859
4.448ProGln: 4.448 ± 0.798
8.087ProArg: 8.087 ± 3.332
6.066ProSer: 6.066 ± 1.107
7.683ProThr: 7.683 ± 1.162
6.066ProVal: 6.066 ± 1.056
0.809ProTrp: 0.809 ± 0.304
2.426ProTyr: 2.426 ± 0.392
0.0ProXaa: 0.0 ± 0.0
Gln
3.235GlnAla: 3.235 ± 1.009
0.809GlnCys: 0.809 ± 0.304
0.0GlnAsp: 0.0 ± 0.0
5.257GlnGlu: 5.257 ± 0.49
0.809GlnPhe: 0.809 ± 0.304
2.831GlnGly: 2.831 ± 0.367
0.809GlnHis: 0.809 ± 0.304
4.448GlnIle: 4.448 ± 0.816
0.404GlnLys: 0.404 ± 0.536
1.617GlnLeu: 1.617 ± 0.984
0.0GlnMet: 0.0 ± 0.0
1.617GlnAsn: 1.617 ± 0.522
5.257GlnPro: 5.257 ± 0.552
1.617GlnGln: 1.617 ± 0.984
3.639GlnArg: 3.639 ± 0.08
2.831GlnSer: 2.831 ± 0.797
2.022GlnThr: 2.022 ± 0.502
3.235GlnVal: 3.235 ± 0.959
0.404GlnTrp: 0.404 ± 0.581
0.809GlnTyr: 0.809 ± 0.304
0.0GlnXaa: 0.0 ± 0.0
Arg
7.683ArgAla: 7.683 ± 1.526
2.426ArgCys: 2.426 ± 0.392
4.448ArgAsp: 4.448 ± 0.816
4.852ArgGlu: 4.852 ± 1.177
4.044ArgPhe: 4.044 ± 1.004
4.448ArgGly: 4.448 ± 2.895
4.852ArgHis: 4.852 ± 1.376
1.617ArgIle: 1.617 ± 0.48
0.809ArgLys: 0.809 ± 1.072
3.235ArgLeu: 3.235 ± 1.227
4.044ArgMet: 4.044 ± 0.745
0.404ArgAsn: 0.404 ± 0.536
6.874ArgPro: 6.874 ± 0.582
1.617ArgGln: 1.617 ± 0.522
4.044ArgArg: 4.044 ± 4.022
2.022ArgSer: 2.022 ± 1.555
1.213ArgThr: 1.213 ± 0.421
10.918ArgVal: 10.918 ± 2.221
1.617ArgTrp: 1.617 ± 0.984
2.022ArgTyr: 2.022 ± 0.483
0.0ArgXaa: 0.0 ± 0.0
Ser
3.235SerAla: 3.235 ± 0.512
0.404SerCys: 0.404 ± 0.581
1.617SerAsp: 1.617 ± 0.608
1.213SerGlu: 1.213 ± 0.421
1.617SerPhe: 1.617 ± 0.608
6.066SerGly: 6.066 ± 4.837
1.213SerHis: 1.213 ± 0.421
4.044SerIle: 4.044 ± 1.184
1.617SerLys: 1.617 ± 0.662
7.279SerLeu: 7.279 ± 1.293
0.0SerMet: 0.0 ± 0.0
0.809SerAsn: 0.809 ± 0.304
4.852SerPro: 4.852 ± 0.407
2.022SerGln: 2.022 ± 0.502
5.661SerArg: 5.661 ± 0.954
5.661SerSer: 5.661 ± 1.859
0.809SerThr: 0.809 ± 0.304
4.852SerVal: 4.852 ± 1.813
2.831SerTrp: 2.831 ± 0.807
2.426SerTyr: 2.426 ± 0.843
0.0SerXaa: 0.0 ± 0.0
Thr
2.831ThrAla: 2.831 ± 1.32
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
0.809ThrGlu: 0.809 ± 1.162
2.022ThrPhe: 2.022 ± 0.584
2.426ThrGly: 2.426 ± 0.392
0.809ThrHis: 0.809 ± 0.304
2.022ThrIle: 2.022 ± 0.584
1.617ThrLys: 1.617 ± 0.608
5.257ThrLeu: 5.257 ± 1.628
2.022ThrMet: 2.022 ± 0.485
2.022ThrAsn: 2.022 ± 0.502
5.257ThrPro: 5.257 ± 1.444
2.022ThrGln: 2.022 ± 0.906
6.874ThrArg: 6.874 ± 0.447
1.213ThrSer: 1.213 ± 0.439
1.213ThrThr: 1.213 ± 1.743
3.639ThrVal: 3.639 ± 0.978
0.0ThrTrp: 0.0 ± 0.0
1.213ThrTyr: 1.213 ± 0.463
0.0ThrXaa: 0.0 ± 0.0
Val
8.087ValAla: 8.087 ± 0.756
2.426ValCys: 2.426 ± 0.402
3.235ValAsp: 3.235 ± 1.216
4.448ValGlu: 4.448 ± 0.734
2.831ValPhe: 2.831 ± 0.946
5.257ValGly: 5.257 ± 0.741
2.426ValHis: 2.426 ± 0.879
4.044ValIle: 4.044 ± 0.703
7.683ValLys: 7.683 ± 1.766
7.279ValLeu: 7.279 ± 0.691
0.0ValMet: 0.0 ± 0.0
6.47ValAsn: 6.47 ± 1.872
2.426ValPro: 2.426 ± 1.095
3.639ValGln: 3.639 ± 1.074
3.235ValArg: 3.235 ± 0.547
4.044ValSer: 4.044 ± 1.004
1.213ValThr: 1.213 ± 0.421
4.852ValVal: 4.852 ± 1.623
1.213ValTrp: 1.213 ± 0.421
3.235ValTyr: 3.235 ± 1.216
0.0ValXaa: 0.0 ± 0.0
Trp
2.426TrpAla: 2.426 ± 0.402
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.213TrpGlu: 1.213 ± 0.439
1.213TrpPhe: 1.213 ± 0.463
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.404TrpIle: 0.404 ± 0.536
1.617TrpLys: 1.617 ± 0.608
2.022TrpLeu: 2.022 ± 0.584
2.022TrpMet: 2.022 ± 0.462
0.0TrpAsn: 0.0 ± 0.0
0.404TrpPro: 0.404 ± 0.581
1.617TrpGln: 1.617 ± 0.48
2.022TrpArg: 2.022 ± 0.584
0.809TrpSer: 0.809 ± 0.304
0.0TrpThr: 0.0 ± 0.0
1.617TrpVal: 1.617 ± 0.48
0.0TrpTrp: 0.0 ± 0.0
3.235TrpTyr: 3.235 ± 1.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.809TyrAla: 0.809 ± 0.304
0.404TyrCys: 0.404 ± 0.581
1.617TyrAsp: 1.617 ± 0.608
2.426TyrGlu: 2.426 ± 0.926
0.809TyrPhe: 0.809 ± 0.304
2.426TyrGly: 2.426 ± 0.392
0.0TyrHis: 0.0 ± 0.0
1.213TyrIle: 1.213 ± 0.421
3.235TyrLys: 3.235 ± 1.216
1.617TyrLeu: 1.617 ± 0.915
2.426TyrMet: 2.426 ± 0.926
1.617TyrAsn: 1.617 ± 0.608
1.213TyrPro: 1.213 ± 0.421
0.809TyrGln: 0.809 ± 0.304
2.831TyrArg: 2.831 ± 0.677
2.022TyrSer: 2.022 ± 0.502
4.448TyrThr: 4.448 ± 1.352
1.213TyrVal: 1.213 ± 0.421
0.0TyrTrp: 0.0 ± 0.0
0.809TyrTyr: 0.809 ± 0.304
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2474 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski