Amino acid dipepetide frequency for Tortoise microvirus 46

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.777AlaAla: 8.777 ± 0.625
0.0AlaCys: 0.0 ± 0.0
2.341AlaAsp: 2.341 ± 1.012
7.607AlaGlu: 7.607 ± 1.837
5.266AlaPhe: 5.266 ± 1.697
9.947AlaGly: 9.947 ± 3.028
2.926AlaHis: 2.926 ± 1.811
0.585AlaIle: 0.585 ± 0.405
5.851AlaLys: 5.851 ± 3.103
11.703AlaLeu: 11.703 ± 2.906
2.341AlaMet: 2.341 ± 0.677
4.681AlaAsn: 4.681 ± 2.224
7.022AlaPro: 7.022 ± 1.866
2.341AlaGln: 2.341 ± 1.196
7.022AlaArg: 7.022 ± 1.057
3.511AlaSer: 3.511 ± 0.941
7.607AlaThr: 7.607 ± 2.778
8.192AlaVal: 8.192 ± 2.482
0.585AlaTrp: 0.585 ± 0.545
2.341AlaTyr: 2.341 ± 1.066
0.0AlaXaa: 0.0 ± 0.0
Cys
1.17CysAla: 1.17 ± 0.823
0.0CysCys: 0.0 ± 0.0
0.585CysAsp: 0.585 ± 0.52
0.585CysGlu: 0.585 ± 0.405
0.0CysPhe: 0.0 ± 0.0
1.17CysGly: 1.17 ± 0.82
0.0CysHis: 0.0 ± 0.0
1.17CysIle: 1.17 ± 1.041
0.585CysLys: 0.585 ± 0.646
1.17CysLeu: 1.17 ± 0.708
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.17CysArg: 1.17 ± 1.041
0.0CysSer: 0.0 ± 0.0
0.585CysThr: 0.585 ± 0.644
0.0CysVal: 0.0 ± 0.0
0.585CysTrp: 0.585 ± 0.52
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.607AspAla: 7.607 ± 2.001
0.0AspCys: 0.0 ± 0.0
4.096AspAsp: 4.096 ± 1.121
2.926AspGlu: 2.926 ± 0.824
3.511AspPhe: 3.511 ± 1.206
6.437AspGly: 6.437 ± 1.317
0.0AspHis: 0.0 ± 0.0
1.755AspIle: 1.755 ± 0.811
2.341AspLys: 2.341 ± 0.664
7.022AspLeu: 7.022 ± 1.309
1.755AspMet: 1.755 ± 1.003
2.341AspAsn: 2.341 ± 1.066
3.511AspPro: 3.511 ± 1.497
2.341AspGln: 2.341 ± 1.066
4.096AspArg: 4.096 ± 0.889
1.17AspSer: 1.17 ± 0.811
1.755AspThr: 1.755 ± 1.171
3.511AspVal: 3.511 ± 2.184
2.341AspTrp: 2.341 ± 1.199
3.511AspTyr: 3.511 ± 1.851
0.0AspXaa: 0.0 ± 0.0
Glu
6.437GluAla: 6.437 ± 2.044
0.585GluCys: 0.585 ± 0.642
4.681GluAsp: 4.681 ± 1.337
3.511GluGlu: 3.511 ± 2.306
1.17GluPhe: 1.17 ± 0.765
0.585GluGly: 0.585 ± 0.405
0.0GluHis: 0.0 ± 0.0
4.096GluIle: 4.096 ± 1.163
1.17GluLys: 1.17 ± 0.735
3.511GluLeu: 3.511 ± 1.441
1.755GluMet: 1.755 ± 0.695
1.755GluAsn: 1.755 ± 1.003
1.755GluPro: 1.755 ± 0.508
4.681GluGln: 4.681 ± 1.052
8.192GluArg: 8.192 ± 1.495
1.755GluSer: 1.755 ± 1.268
2.341GluThr: 2.341 ± 0.921
4.096GluVal: 4.096 ± 0.784
1.755GluTrp: 1.755 ± 0.508
2.926GluTyr: 2.926 ± 0.946
0.0GluXaa: 0.0 ± 0.0
Phe
2.926PheAla: 2.926 ± 1.14
1.17PheCys: 1.17 ± 0.76
2.926PheAsp: 2.926 ± 1.138
2.926PheGlu: 2.926 ± 0.978
2.341PhePhe: 2.341 ± 1.015
2.926PheGly: 2.926 ± 1.116
0.585PheHis: 0.585 ± 0.405
1.755PheIle: 1.755 ± 1.381
1.17PheLys: 1.17 ± 0.708
2.926PheLeu: 2.926 ± 1.468
0.585PheMet: 0.585 ± 0.545
2.926PheAsn: 2.926 ± 2.592
1.755PhePro: 1.755 ± 0.916
1.755PheGln: 1.755 ± 0.718
4.681PheArg: 4.681 ± 0.89
1.17PheSer: 1.17 ± 1.041
0.585PheThr: 0.585 ± 0.405
2.926PheVal: 2.926 ± 1.141
0.585PheTrp: 0.585 ± 0.405
2.926PheTyr: 2.926 ± 1.534
0.0PheXaa: 0.0 ± 0.0
Gly
9.362GlyAla: 9.362 ± 1.964
1.17GlyCys: 1.17 ± 0.76
4.096GlyAsp: 4.096 ± 0.784
1.755GlyGlu: 1.755 ± 0.508
4.096GlyPhe: 4.096 ± 1.251
5.851GlyGly: 5.851 ± 3.054
0.0GlyHis: 0.0 ± 0.0
3.511GlyIle: 3.511 ± 2.433
8.777GlyLys: 8.777 ± 2.119
2.926GlyLeu: 2.926 ± 1.274
4.681GlyMet: 4.681 ± 1.569
0.585GlyAsn: 0.585 ± 0.642
1.755GlyPro: 1.755 ± 1.636
3.511GlyGln: 3.511 ± 1.083
5.851GlyArg: 5.851 ± 1.066
7.607GlySer: 7.607 ± 1.431
4.096GlyThr: 4.096 ± 1.187
8.192GlyVal: 8.192 ± 1.615
1.17GlyTrp: 1.17 ± 0.903
2.341GlyTyr: 2.341 ± 0.662
0.0GlyXaa: 0.0 ± 0.0
His
2.341HisAla: 2.341 ± 0.664
0.0HisCys: 0.0 ± 0.0
0.585HisAsp: 0.585 ± 0.616
1.755HisGlu: 1.755 ± 1.069
0.585HisPhe: 0.585 ± 0.405
2.341HisGly: 2.341 ± 1.645
0.0HisHis: 0.0 ± 0.0
0.585HisIle: 0.585 ± 0.52
0.0HisLys: 0.0 ± 0.0
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.585HisPro: 0.585 ± 0.642
1.755HisGln: 1.755 ± 1.381
1.755HisArg: 1.755 ± 0.833
0.585HisSer: 0.585 ± 0.405
0.585HisThr: 0.585 ± 0.405
2.341HisVal: 2.341 ± 0.766
1.755HisTrp: 1.755 ± 1.218
1.17HisTyr: 1.17 ± 1.041
0.0HisXaa: 0.0 ± 0.0
Ile
4.096IleAla: 4.096 ± 0.929
0.585IleCys: 0.585 ± 0.52
4.681IleAsp: 4.681 ± 1.838
1.755IleGlu: 1.755 ± 0.78
2.341IlePhe: 2.341 ± 0.662
2.341IleGly: 2.341 ± 0.866
0.585IleHis: 0.585 ± 0.405
1.755IleIle: 1.755 ± 0.78
1.755IleLys: 1.755 ± 0.918
2.926IleLeu: 2.926 ± 2.064
0.585IleMet: 0.585 ± 0.405
1.17IleAsn: 1.17 ± 0.811
1.755IlePro: 1.755 ± 0.979
2.341IleGln: 2.341 ± 1.315
1.755IleArg: 1.755 ± 0.926
0.585IleSer: 0.585 ± 0.545
1.17IleThr: 1.17 ± 0.811
3.511IleVal: 3.511 ± 0.724
0.585IleTrp: 0.585 ± 0.405
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.096LysAla: 4.096 ± 2.2
0.0LysCys: 0.0 ± 0.0
6.437LysAsp: 6.437 ± 1.7
3.511LysGlu: 3.511 ± 1.435
3.511LysPhe: 3.511 ± 1.51
4.681LysGly: 4.681 ± 1.41
1.17LysHis: 1.17 ± 1.041
0.585LysIle: 0.585 ± 0.405
2.926LysLys: 2.926 ± 1.378
3.511LysLeu: 3.511 ± 1.242
0.585LysMet: 0.585 ± 0.52
1.755LysAsn: 1.755 ± 0.721
2.341LysPro: 2.341 ± 1.381
2.926LysGln: 2.926 ± 1.415
4.096LysArg: 4.096 ± 2.2
2.341LysSer: 2.341 ± 0.904
1.755LysThr: 1.755 ± 0.57
1.755LysVal: 1.755 ± 1.216
0.585LysTrp: 0.585 ± 0.644
3.511LysTyr: 3.511 ± 1.3
0.0LysXaa: 0.0 ± 0.0
Leu
11.703LeuAla: 11.703 ± 1.768
0.0LeuCys: 0.0 ± 0.0
5.851LeuAsp: 5.851 ± 0.674
2.926LeuGlu: 2.926 ± 0.773
2.926LeuPhe: 2.926 ± 1.25
8.777LeuGly: 8.777 ± 1.539
0.585LeuHis: 0.585 ± 0.616
2.926LeuIle: 2.926 ± 1.208
6.437LeuLys: 6.437 ± 3.198
8.192LeuLeu: 8.192 ± 1.854
0.585LeuMet: 0.585 ± 0.405
2.926LeuAsn: 2.926 ± 1.617
5.851LeuPro: 5.851 ± 1.86
1.17LeuGln: 1.17 ± 0.811
5.266LeuArg: 5.266 ± 1.593
3.511LeuSer: 3.511 ± 0.979
5.851LeuThr: 5.851 ± 1.259
5.851LeuVal: 5.851 ± 1.446
0.0LeuTrp: 0.0 ± 0.0
0.585LeuTyr: 0.585 ± 0.405
0.0LeuXaa: 0.0 ± 0.0
Met
2.341MetAla: 2.341 ± 0.944
0.585MetCys: 0.585 ± 0.52
0.585MetAsp: 0.585 ± 0.405
1.755MetGlu: 1.755 ± 1.003
1.755MetPhe: 1.755 ± 1.183
1.755MetGly: 1.755 ± 1.636
0.0MetHis: 0.0 ± 0.0
0.585MetIle: 0.585 ± 0.545
0.585MetLys: 0.585 ± 0.642
0.0MetLeu: 0.0 ± 0.0
1.755MetMet: 1.755 ± 0.736
0.585MetAsn: 0.585 ± 0.405
1.755MetPro: 1.755 ± 0.721
0.0MetGln: 0.0 ± 0.0
2.926MetArg: 2.926 ± 1.002
2.926MetSer: 2.926 ± 0.845
1.755MetThr: 1.755 ± 0.801
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.266AsnAla: 5.266 ± 1.549
1.17AsnCys: 1.17 ± 0.48
2.341AsnAsp: 2.341 ± 0.86
2.926AsnGlu: 2.926 ± 1.09
1.755AsnPhe: 1.755 ± 0.736
1.755AsnGly: 1.755 ± 0.78
1.17AsnHis: 1.17 ± 0.811
2.926AsnIle: 2.926 ± 1.138
2.341AsnLys: 2.341 ± 1.09
2.341AsnLeu: 2.341 ± 0.663
0.585AsnMet: 0.585 ± 0.545
2.926AsnAsn: 2.926 ± 1.443
1.755AsnPro: 1.755 ± 0.78
0.0AsnGln: 0.0 ± 0.0
1.755AsnArg: 1.755 ± 1.216
4.096AsnSer: 4.096 ± 0.651
1.17AsnThr: 1.17 ± 0.811
1.17AsnVal: 1.17 ± 0.686
0.585AsnTrp: 0.585 ± 0.405
0.585AsnTyr: 0.585 ± 0.545
0.0AsnXaa: 0.0 ± 0.0
Pro
5.851ProAla: 5.851 ± 2.719
0.585ProCys: 0.585 ± 0.644
4.681ProAsp: 4.681 ± 0.934
5.851ProGlu: 5.851 ± 1.343
1.755ProPhe: 1.755 ± 0.57
1.755ProGly: 1.755 ± 1.432
1.755ProHis: 1.755 ± 0.65
1.17ProIle: 1.17 ± 0.537
1.17ProLys: 1.17 ± 0.537
6.437ProLeu: 6.437 ± 1.269
1.17ProMet: 1.17 ± 0.868
1.17ProAsn: 1.17 ± 0.765
1.755ProPro: 1.755 ± 0.971
2.341ProGln: 2.341 ± 1.41
1.17ProArg: 1.17 ± 0.686
3.511ProSer: 3.511 ± 1.864
1.755ProThr: 1.755 ± 0.736
9.362ProVal: 9.362 ± 3.3
1.17ProTrp: 1.17 ± 0.735
1.17ProTyr: 1.17 ± 0.537
0.0ProXaa: 0.0 ± 0.0
Gln
4.096GlnAla: 4.096 ± 1.915
0.585GlnCys: 0.585 ± 0.52
2.926GlnAsp: 2.926 ± 0.564
1.755GlnGlu: 1.755 ± 0.916
1.17GlnPhe: 1.17 ± 0.686
2.926GlnGly: 2.926 ± 0.554
0.585GlnHis: 0.585 ± 0.616
0.585GlnIle: 0.585 ± 0.405
1.17GlnLys: 1.17 ± 0.811
2.926GlnLeu: 2.926 ± 1.426
1.17GlnMet: 1.17 ± 0.78
1.755GlnAsn: 1.755 ± 0.57
1.17GlnPro: 1.17 ± 0.537
2.341GlnGln: 2.341 ± 0.645
3.511GlnArg: 3.511 ± 0.979
4.096GlnSer: 4.096 ± 1.508
3.511GlnThr: 3.511 ± 1.141
0.0GlnVal: 0.0 ± 0.0
3.511GlnTrp: 3.511 ± 0.977
2.341GlnTyr: 2.341 ± 1.292
0.0GlnXaa: 0.0 ± 0.0
Arg
6.437ArgAla: 6.437 ± 1.694
0.585ArgCys: 0.585 ± 0.52
2.926ArgAsp: 2.926 ± 0.824
4.096ArgGlu: 4.096 ± 0.65
2.341ArgPhe: 2.341 ± 1.015
4.681ArgGly: 4.681 ± 1.411
1.17ArgHis: 1.17 ± 1.041
1.755ArgIle: 1.755 ± 1.216
5.266ArgLys: 5.266 ± 1.302
5.851ArgLeu: 5.851 ± 0.998
2.341ArgMet: 2.341 ± 0.845
4.096ArgAsn: 4.096 ± 0.913
2.926ArgPro: 2.926 ± 1.534
6.437ArgGln: 6.437 ± 2.273
6.437ArgArg: 6.437 ± 1.382
2.926ArgSer: 2.926 ± 0.967
4.096ArgThr: 4.096 ± 1.774
5.266ArgVal: 5.266 ± 1.578
0.0ArgTrp: 0.0 ± 0.0
3.511ArgTyr: 3.511 ± 1.23
0.0ArgXaa: 0.0 ± 0.0
Ser
4.681SerAla: 4.681 ± 1.084
0.0SerCys: 0.0 ± 0.0
2.341SerAsp: 2.341 ± 1.06
2.926SerGlu: 2.926 ± 1.322
3.511SerPhe: 3.511 ± 1.141
5.851SerGly: 5.851 ± 1.213
0.585SerHis: 0.585 ± 0.405
2.341SerIle: 2.341 ± 1.274
2.341SerLys: 2.341 ± 1.152
3.511SerLeu: 3.511 ± 1.441
0.585SerMet: 0.585 ± 0.405
1.755SerAsn: 1.755 ± 0.919
2.926SerPro: 2.926 ± 1.266
1.17SerGln: 1.17 ± 0.811
2.926SerArg: 2.926 ± 1.358
3.511SerSer: 3.511 ± 1.145
4.096SerThr: 4.096 ± 1.26
4.681SerVal: 4.681 ± 1.446
0.0SerTrp: 0.0 ± 0.0
1.17SerTyr: 1.17 ± 0.637
0.0SerXaa: 0.0 ± 0.0
Thr
3.511ThrAla: 3.511 ± 1.421
1.17ThrCys: 1.17 ± 0.735
2.926ThrAsp: 2.926 ± 1.138
3.511ThrGlu: 3.511 ± 0.724
0.585ThrPhe: 0.585 ± 0.646
7.022ThrGly: 7.022 ± 1.647
1.755ThrHis: 1.755 ± 1.069
1.17ThrIle: 1.17 ± 0.537
1.755ThrLys: 1.755 ± 0.621
5.266ThrLeu: 5.266 ± 1.679
0.0ThrMet: 0.0 ± 0.0
0.585ThrAsn: 0.585 ± 0.405
3.511ThrPro: 3.511 ± 1.097
1.755ThrGln: 1.755 ± 0.508
4.096ThrArg: 4.096 ± 1.365
2.341ThrSer: 2.341 ± 1.253
7.607ThrThr: 7.607 ± 3.602
4.681ThrVal: 4.681 ± 2.017
1.755ThrTrp: 1.755 ± 0.65
1.755ThrTyr: 1.755 ± 0.57
0.0ThrXaa: 0.0 ± 0.0
Val
5.851ValAla: 5.851 ± 1.678
0.0ValCys: 0.0 ± 0.0
4.681ValAsp: 4.681 ± 1.54
4.096ValGlu: 4.096 ± 2.275
1.17ValPhe: 1.17 ± 0.686
6.437ValGly: 6.437 ± 1.035
4.096ValHis: 4.096 ± 1.761
2.926ValIle: 2.926 ± 1.304
3.511ValLys: 3.511 ± 0.82
6.437ValLeu: 6.437 ± 1.347
0.0ValMet: 0.0 ± 0.0
2.341ValAsn: 2.341 ± 1.066
11.118ValPro: 11.118 ± 1.019
2.341ValGln: 2.341 ± 0.645
4.096ValArg: 4.096 ± 0.929
3.511ValSer: 3.511 ± 1.031
3.511ValThr: 3.511 ± 1.071
4.681ValVal: 4.681 ± 2.112
0.0ValTrp: 0.0 ± 0.0
1.17ValTyr: 1.17 ± 0.48
0.0ValXaa: 0.0 ± 0.0
Trp
0.585TrpAla: 0.585 ± 0.642
0.585TrpCys: 0.585 ± 0.646
1.17TrpAsp: 1.17 ± 0.811
0.585TrpGlu: 0.585 ± 0.642
0.0TrpPhe: 0.0 ± 0.0
0.585TrpGly: 0.585 ± 0.642
1.17TrpHis: 1.17 ± 1.041
1.17TrpIle: 1.17 ± 0.686
2.341TrpLys: 2.341 ± 1.199
1.17TrpLeu: 1.17 ± 0.537
0.585TrpMet: 0.585 ± 0.405
1.755TrpAsn: 1.755 ± 0.801
0.585TrpPro: 0.585 ± 0.52
1.17TrpGln: 1.17 ± 0.637
1.17TrpArg: 1.17 ± 0.48
0.585TrpSer: 0.585 ± 0.405
0.585TrpThr: 0.585 ± 0.405
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.17TrpTyr: 1.17 ± 0.686
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.511TyrAla: 3.511 ± 1.354
0.0TyrCys: 0.0 ± 0.0
1.17TyrAsp: 1.17 ± 0.78
0.0TyrGlu: 0.0 ± 0.0
1.755TyrPhe: 1.755 ± 1.561
3.511TyrGly: 3.511 ± 1.133
0.585TyrHis: 0.585 ± 0.52
2.926TyrIle: 2.926 ± 0.845
0.585TyrLys: 0.585 ± 0.405
4.096TyrLeu: 4.096 ± 1.274
0.0TyrMet: 0.0 ± 0.0
3.511TyrAsn: 3.511 ± 1.471
1.755TyrPro: 1.755 ± 0.812
1.755TyrGln: 1.755 ± 0.78
1.755TyrArg: 1.755 ± 0.916
1.17TyrSer: 1.17 ± 0.637
2.341TyrThr: 2.341 ± 1.056
1.755TyrVal: 1.755 ± 0.801
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1710 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski