Amino acid dipepetide frequency for Citrus leaf blotch virus (isolate Nagami kumquat/France/SRA-153/1984) (CLBV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.701AlaAla: 6.701 ± 3.113
1.117AlaCys: 1.117 ± 0.594
4.095AlaAsp: 4.095 ± 1.438
4.095AlaGlu: 4.095 ± 3.033
4.84AlaPhe: 4.84 ± 0.703
3.351AlaGly: 3.351 ± 1.244
1.489AlaHis: 1.489 ± 0.607
6.701AlaIle: 6.701 ± 3.986
2.606AlaLys: 2.606 ± 1.01
5.212AlaLeu: 5.212 ± 1.797
1.117AlaMet: 1.117 ± 0.623
3.351AlaAsn: 3.351 ± 1.686
1.489AlaPro: 1.489 ± 1.526
1.862AlaGln: 1.862 ± 0.99
2.606AlaArg: 2.606 ± 0.082
4.095AlaSer: 4.095 ± 2.335
0.745AlaThr: 0.745 ± 1.631
3.351AlaVal: 3.351 ± 1.155
0.372AlaTrp: 0.372 ± 0.198
2.978AlaTyr: 2.978 ± 0.116
0.0AlaXaa: 0.0 ± 0.0
Cys
2.234CysAla: 2.234 ± 0.28
0.0CysCys: 0.0 ± 0.0
1.117CysAsp: 1.117 ± 0.62
0.372CysGlu: 0.372 ± 0.198
1.489CysPhe: 1.489 ± 0.792
2.234CysGly: 2.234 ± 0.75
0.372CysHis: 0.372 ± 0.198
0.372CysIle: 0.372 ± 0.198
1.489CysLys: 1.489 ± 0.61
1.862CysLeu: 1.862 ± 0.99
0.372CysMet: 0.372 ± 0.198
0.745CysAsn: 0.745 ± 0.689
0.0CysPro: 0.0 ± 0.0
1.117CysGln: 1.117 ± 0.594
1.117CysArg: 1.117 ± 0.594
1.117CysSer: 1.117 ± 0.594
1.862CysThr: 1.862 ± 0.663
1.862CysVal: 1.862 ± 0.99
0.0CysTrp: 0.0 ± 0.0
0.372CysTyr: 0.372 ± 0.198
0.0CysXaa: 0.0 ± 0.0
Asp
3.351AspAla: 3.351 ± 1.22
0.745AspCys: 0.745 ± 0.396
4.468AspAsp: 4.468 ± 1.74
6.701AspGlu: 6.701 ± 2.388
2.234AspPhe: 2.234 ± 0.75
2.234AspGly: 2.234 ± 1.247
0.745AspHis: 0.745 ± 0.689
4.095AspIle: 4.095 ± 3.317
2.978AspLys: 2.978 ± 0.86
5.957AspLeu: 5.957 ± 0.784
1.862AspMet: 1.862 ± 0.99
1.117AspAsn: 1.117 ± 0.623
3.723AspPro: 3.723 ± 1.305
1.117AspGln: 1.117 ± 0.62
4.468AspArg: 4.468 ± 0.561
0.745AspSer: 0.745 ± 0.396
2.234AspThr: 2.234 ± 2.547
5.212AspVal: 5.212 ± 2.772
1.489AspTrp: 1.489 ± 0.61
2.234AspTyr: 2.234 ± 0.764
0.0AspXaa: 0.0 ± 0.0
Glu
4.84GluAla: 4.84 ± 1.261
1.117GluCys: 1.117 ± 0.62
2.978GluAsp: 2.978 ± 0.872
11.541GluGlu: 11.541 ± 1.18
5.585GluPhe: 5.585 ± 0.988
3.723GluGly: 3.723 ± 0.644
2.234GluHis: 2.234 ± 1.247
4.468GluIle: 4.468 ± 0.908
5.585GluLys: 5.585 ± 2.97
4.468GluLeu: 4.468 ± 0.908
1.117GluMet: 1.117 ± 0.623
4.468GluAsn: 4.468 ± 0.625
2.978GluPro: 2.978 ± 1.213
5.585GluGln: 5.585 ± 3.129
5.212GluArg: 5.212 ± 2.137
6.329GluSer: 6.329 ± 1.607
3.351GluThr: 3.351 ± 1.86
4.84GluVal: 4.84 ± 0.363
1.489GluTrp: 1.489 ± 0.792
1.489GluTyr: 1.489 ± 0.607
0.0GluXaa: 0.0 ± 0.0
Phe
4.84PheAla: 4.84 ± 2.136
2.606PheCys: 2.606 ± 0.881
4.095PheAsp: 4.095 ± 1.556
7.818PheGlu: 7.818 ± 2.058
4.84PhePhe: 4.84 ± 1.624
1.862PheGly: 1.862 ± 0.663
1.117PheHis: 1.117 ± 0.594
3.351PheIle: 3.351 ± 1.782
4.095PheLys: 4.095 ± 1.819
5.957PheLeu: 5.957 ± 2.498
1.117PheMet: 1.117 ± 0.594
5.212PheAsn: 5.212 ± 0.822
1.862PhePro: 1.862 ± 0.99
1.862PheGln: 1.862 ± 0.99
3.351PheArg: 3.351 ± 1.201
5.957PheSer: 5.957 ± 2.069
3.351PheThr: 3.351 ± 0.314
1.489PheVal: 1.489 ± 0.61
1.117PheTrp: 1.117 ± 0.594
1.117PheTyr: 1.117 ± 1.505
0.0PheXaa: 0.0 ± 0.0
Gly
1.117GlyAla: 1.117 ± 0.623
0.745GlyCys: 0.745 ± 0.396
3.351GlyAsp: 3.351 ± 1.201
2.606GlyGlu: 2.606 ± 0.898
4.84GlyPhe: 4.84 ± 0.363
1.862GlyGly: 1.862 ± 0.99
2.606GlyHis: 2.606 ± 1.214
3.723GlyIle: 3.723 ± 1.305
3.723GlyLys: 3.723 ± 0.644
3.723GlyLeu: 3.723 ± 1.325
0.372GlyMet: 0.372 ± 0.198
3.351GlyAsn: 3.351 ± 1.86
1.117GlyPro: 1.117 ± 0.594
2.606GlyGln: 2.606 ± 0.898
2.606GlyArg: 2.606 ± 1.953
5.957GlySer: 5.957 ± 4.365
1.862GlyThr: 1.862 ± 1.364
2.234GlyVal: 2.234 ± 0.764
0.372GlyTrp: 0.372 ± 0.198
1.117GlyTyr: 1.117 ± 0.594
0.0GlyXaa: 0.0 ± 0.0
His
0.745HisAla: 0.745 ± 1.631
0.372HisCys: 0.372 ± 0.198
2.234HisAsp: 2.234 ± 0.764
0.745HisGlu: 0.745 ± 0.698
2.606HisPhe: 2.606 ± 1.386
1.117HisGly: 1.117 ± 0.875
0.745HisHis: 0.745 ± 0.396
1.117HisIle: 1.117 ± 0.594
0.745HisLys: 0.745 ± 0.689
4.468HisLeu: 4.468 ± 0.908
0.745HisMet: 0.745 ± 0.698
1.489HisAsn: 1.489 ± 0.792
0.372HisPro: 0.372 ± 0.198
0.745HisGln: 0.745 ± 0.689
1.489HisArg: 1.489 ± 0.792
3.351HisSer: 3.351 ± 1.782
0.372HisThr: 0.372 ± 0.198
2.606HisVal: 2.606 ± 1.024
0.372HisTrp: 0.372 ± 0.198
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.978IleAla: 2.978 ± 0.872
1.489IleCys: 1.489 ± 0.792
4.095IleAsp: 4.095 ± 1.819
6.329IleGlu: 6.329 ± 2.177
3.351IlePhe: 3.351 ± 1.201
2.606IleGly: 2.606 ± 1.01
1.117IleHis: 1.117 ± 0.594
4.468IleIle: 4.468 ± 1.422
3.723IleLys: 3.723 ± 0.644
6.329IleLeu: 6.329 ± 1.301
0.372IleMet: 0.372 ± 0.36
5.212IleAsn: 5.212 ± 2.017
2.606IlePro: 2.606 ± 1.024
1.117IleGln: 1.117 ± 0.62
5.212IleArg: 5.212 ± 1.091
3.351IleSer: 3.351 ± 1.87
4.84IleThr: 4.84 ± 2.136
1.489IleVal: 1.489 ± 0.607
0.372IleTrp: 0.372 ± 0.802
2.606IleTyr: 2.606 ± 0.881
0.0IleXaa: 0.0 ± 0.0
Lys
5.585LysAla: 5.585 ± 0.921
1.117LysCys: 1.117 ± 0.594
4.095LysAsp: 4.095 ± 2.228
4.095LysGlu: 4.095 ± 1.576
3.351LysPhe: 3.351 ± 1.155
4.095LysGly: 4.095 ± 0.604
1.489LysHis: 1.489 ± 0.792
5.212LysIle: 5.212 ± 1.091
8.191LysLys: 8.191 ± 1.208
6.701LysLeu: 6.701 ± 1.467
2.234LysMet: 2.234 ± 1.827
1.489LysAsn: 1.489 ± 0.607
0.745LysPro: 0.745 ± 0.396
1.862LysGln: 1.862 ± 0.663
4.468LysArg: 4.468 ± 0.635
4.468LysSer: 4.468 ± 0.908
2.606LysThr: 2.606 ± 0.082
7.446LysVal: 7.446 ± 0.68
0.372LysTrp: 0.372 ± 0.802
1.862LysTyr: 1.862 ± 0.479
0.0LysXaa: 0.0 ± 0.0
Leu
5.212LeuAla: 5.212 ± 2.038
2.234LeuCys: 2.234 ± 0.764
3.351LeuAsp: 3.351 ± 1.258
11.169LeuGlu: 11.169 ± 1.016
5.957LeuPhe: 5.957 ± 3.168
5.212LeuGly: 5.212 ± 1.797
2.234LeuHis: 2.234 ± 2.112
5.585LeuIle: 5.585 ± 1.216
7.446LeuLys: 7.446 ± 2.179
6.329LeuLeu: 6.329 ± 1.841
2.978LeuMet: 2.978 ± 1.053
5.212LeuAsn: 5.212 ± 2.116
2.234LeuPro: 2.234 ± 0.764
2.606LeuGln: 2.606 ± 1.01
3.351LeuArg: 3.351 ± 0.733
4.468LeuSer: 4.468 ± 2.376
6.701LeuThr: 6.701 ± 2.31
5.957LeuVal: 5.957 ± 2.441
0.372LeuTrp: 0.372 ± 0.198
2.978LeuTyr: 2.978 ± 0.872
0.0LeuXaa: 0.0 ± 0.0
Met
2.234MetAla: 2.234 ± 0.764
1.117MetCys: 1.117 ± 0.594
0.372MetAsp: 0.372 ± 0.198
1.489MetGlu: 1.489 ± 0.792
1.117MetPhe: 1.117 ± 0.62
0.372MetGly: 0.372 ± 0.198
0.0MetHis: 0.0 ± 0.0
0.372MetIle: 0.372 ± 0.198
2.234MetLys: 2.234 ± 0.28
1.489MetLeu: 1.489 ± 0.792
0.372MetMet: 0.372 ± 0.565
0.372MetAsn: 0.372 ± 0.198
0.745MetPro: 0.745 ± 0.689
0.0MetGln: 0.0 ± 0.0
1.117MetArg: 1.117 ± 1.505
1.489MetSer: 1.489 ± 0.792
1.489MetThr: 1.489 ± 0.792
2.234MetVal: 2.234 ± 1.24
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.212AsnAla: 5.212 ± 2.019
1.862AsnCys: 1.862 ± 0.663
2.978AsnAsp: 2.978 ± 1.83
4.095AsnGlu: 4.095 ± 2.369
4.095AsnPhe: 4.095 ± 1.556
4.468AsnGly: 4.468 ± 1.761
1.489AsnHis: 1.489 ± 0.792
1.862AsnIle: 1.862 ± 1.296
4.095AsnLys: 4.095 ± 0.759
4.095AsnLeu: 4.095 ± 1.603
1.489AsnMet: 1.489 ± 0.61
1.117AsnAsn: 1.117 ± 0.594
0.745AsnPro: 0.745 ± 0.396
1.117AsnGln: 1.117 ± 0.594
2.606AsnArg: 2.606 ± 0.082
5.212AsnSer: 5.212 ± 1.892
2.234AsnThr: 2.234 ± 0.75
2.234AsnVal: 2.234 ± 0.764
0.372AsnTrp: 0.372 ± 0.816
2.234AsnTyr: 2.234 ± 0.75
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.117ProCys: 1.117 ± 0.594
1.489ProAsp: 1.489 ± 0.792
2.234ProGlu: 2.234 ± 1.247
2.978ProPhe: 2.978 ± 0.872
1.117ProGly: 1.117 ± 0.62
1.117ProHis: 1.117 ± 0.594
2.978ProIle: 2.978 ± 1.053
2.234ProLys: 2.234 ± 1.24
3.723ProLeu: 3.723 ± 0.957
0.372ProMet: 0.372 ± 0.198
2.606ProAsn: 2.606 ± 1.386
1.117ProPro: 1.117 ± 1.505
1.117ProGln: 1.117 ± 0.623
0.372ProArg: 0.372 ± 0.198
2.234ProSer: 2.234 ± 0.28
1.862ProThr: 1.862 ± 1.364
0.745ProVal: 0.745 ± 1.073
0.372ProTrp: 0.372 ± 0.198
0.745ProTyr: 0.745 ± 0.698
0.0ProXaa: 0.0 ± 0.0
Gln
3.351GlnAla: 3.351 ± 1.86
0.0GlnCys: 0.0 ± 0.0
0.372GlnAsp: 0.372 ± 0.198
0.745GlnGlu: 0.745 ± 0.689
3.351GlnPhe: 3.351 ± 1.244
1.489GlnGly: 1.489 ± 0.792
0.372GlnHis: 0.372 ± 0.198
2.606GlnIle: 2.606 ± 0.898
1.862GlnLys: 1.862 ± 0.99
2.978GlnLeu: 2.978 ± 2.789
0.372GlnMet: 0.372 ± 0.198
1.117GlnAsn: 1.117 ± 0.623
1.117GlnPro: 1.117 ± 0.875
0.745GlnGln: 0.745 ± 1.631
2.606GlnArg: 2.606 ± 0.881
2.978GlnSer: 2.978 ± 1.802
1.489GlnThr: 1.489 ± 0.792
2.234GlnVal: 2.234 ± 1.24
0.745GlnTrp: 0.745 ± 0.689
0.372GlnTyr: 0.372 ± 0.198
0.0GlnXaa: 0.0 ± 0.0
Arg
1.489ArgAla: 1.489 ± 0.677
0.372ArgCys: 0.372 ± 0.802
2.234ArgAsp: 2.234 ± 0.764
4.095ArgGlu: 4.095 ± 0.71
3.723ArgPhe: 3.723 ± 1.98
2.606ArgGly: 2.606 ± 0.881
1.117ArgHis: 1.117 ± 0.594
1.862ArgIle: 1.862 ± 0.99
5.585ArgLys: 5.585 ± 0.932
6.701ArgLeu: 6.701 ± 1.501
0.372ArgMet: 0.372 ± 0.198
3.723ArgAsn: 3.723 ± 2.426
1.489ArgPro: 1.489 ± 0.607
2.234ArgGln: 2.234 ± 0.75
2.606ArgArg: 2.606 ± 1.214
3.723ArgSer: 3.723 ± 2.463
3.723ArgThr: 3.723 ± 0.957
3.351ArgVal: 3.351 ± 0.742
0.372ArgTrp: 0.372 ± 0.198
2.978ArgTyr: 2.978 ± 1.213
0.0ArgXaa: 0.0 ± 0.0
Ser
3.351SerAla: 3.351 ± 1.244
0.745SerCys: 0.745 ± 0.698
7.074SerAsp: 7.074 ± 1.513
3.351SerGlu: 3.351 ± 0.314
2.606SerPhe: 2.606 ± 1.386
3.351SerGly: 3.351 ± 1.993
2.978SerHis: 2.978 ± 0.116
8.563SerIle: 8.563 ± 1.082
5.585SerLys: 5.585 ± 1.208
8.191SerLeu: 8.191 ± 2.873
0.372SerMet: 0.372 ± 0.198
2.978SerAsn: 2.978 ± 0.116
2.234SerPro: 2.234 ± 0.75
2.606SerGln: 2.606 ± 1.024
4.84SerArg: 4.84 ± 0.703
4.468SerSer: 4.468 ± 3.684
3.351SerThr: 3.351 ± 0.733
1.862SerVal: 1.862 ± 1.347
1.117SerTrp: 1.117 ± 0.594
3.351SerTyr: 3.351 ± 1.201
0.0SerXaa: 0.0 ± 0.0
Thr
2.978ThrAla: 2.978 ± 3.053
1.117ThrCys: 1.117 ± 0.62
2.606ThrAsp: 2.606 ± 0.082
4.095ThrGlu: 4.095 ± 1.815
5.585ThrPhe: 5.585 ± 2.97
2.606ThrGly: 2.606 ± 2.355
1.862ThrHis: 1.862 ± 0.99
2.234ThrIle: 2.234 ± 1.174
4.095ThrLys: 4.095 ± 1.62
3.723ThrLeu: 3.723 ± 1.375
0.745ThrMet: 0.745 ± 0.396
2.234ThrAsn: 2.234 ± 1.19
2.978ThrPro: 2.978 ± 1.802
0.745ThrGln: 0.745 ± 0.698
1.862ThrArg: 1.862 ± 1.296
4.84ThrSer: 4.84 ± 3.059
0.745ThrThr: 0.745 ± 0.689
2.606ThrVal: 2.606 ± 0.082
0.0ThrTrp: 0.0 ± 0.0
0.372ThrTyr: 0.372 ± 0.198
0.0ThrXaa: 0.0 ± 0.0
Val
1.862ValAla: 1.862 ± 0.479
1.862ValCys: 1.862 ± 0.99
5.212ValAsp: 5.212 ± 1.223
4.095ValGlu: 4.095 ± 0.604
3.723ValPhe: 3.723 ± 0.647
2.234ValGly: 2.234 ± 0.28
2.234ValHis: 2.234 ± 0.28
1.862ValIle: 1.862 ± 1.296
4.095ValLys: 4.095 ± 2.529
3.723ValLeu: 3.723 ± 1.325
1.117ValMet: 1.117 ± 0.62
3.723ValAsn: 3.723 ± 0.644
1.117ValPro: 1.117 ± 0.62
1.117ValGln: 1.117 ± 0.623
2.606ValArg: 2.606 ± 1.024
4.468ValSer: 4.468 ± 1.831
3.723ValThr: 3.723 ± 0.512
3.351ValVal: 3.351 ± 1.244
0.372ValTrp: 0.372 ± 0.198
3.723ValTyr: 3.723 ± 1.375
0.0ValXaa: 0.0 ± 0.0
Trp
0.745TrpAla: 0.745 ± 0.396
0.372TrpCys: 0.372 ± 0.198
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.489TrpGly: 1.489 ± 1.378
0.0TrpHis: 0.0 ± 0.0
0.372TrpIle: 0.372 ± 0.198
0.372TrpLys: 0.372 ± 0.198
1.862TrpLeu: 1.862 ± 0.479
0.745TrpMet: 0.745 ± 0.396
0.745TrpAsn: 0.745 ± 0.698
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.117TrpArg: 1.117 ± 0.623
0.745TrpSer: 0.745 ± 0.689
0.745TrpThr: 0.745 ± 0.396
0.745TrpVal: 0.745 ± 0.396
0.0TrpTrp: 0.0 ± 0.0
0.372TrpTyr: 0.372 ± 0.198
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.351TyrAla: 3.351 ± 2.7
0.0TyrCys: 0.0 ± 0.0
1.489TyrAsp: 1.489 ± 0.607
3.723TyrGlu: 3.723 ± 1.305
0.745TyrPhe: 0.745 ± 0.396
1.862TyrGly: 1.862 ± 0.479
1.117TyrHis: 1.117 ± 0.594
2.234TyrIle: 2.234 ± 0.75
0.745TyrLys: 0.745 ± 0.396
4.095TyrLeu: 4.095 ± 1.416
0.0TyrMet: 0.0 ± 0.0
3.351TyrAsn: 3.351 ± 1.201
1.862TyrPro: 1.862 ± 0.653
0.745TyrGln: 0.745 ± 0.396
0.745TyrArg: 0.745 ± 0.396
2.978TyrSer: 2.978 ± 1.034
0.745TyrThr: 0.745 ± 0.396
0.372TyrVal: 0.372 ± 0.802
0.745TyrTrp: 0.745 ± 1.631
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2687 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski