Amino acid dipepetide frequency for Potato aucuba mosaic virus (PAMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.717AlaAla: 6.717 ± 2.298
0.84AlaCys: 0.84 ± 0.41
1.679AlaAsp: 1.679 ± 1.366
5.877AlaGlu: 5.877 ± 1.441
3.778AlaPhe: 3.778 ± 0.955
5.038AlaGly: 5.038 ± 1.448
2.099AlaHis: 2.099 ± 0.539
5.458AlaIle: 5.458 ± 2.535
5.458AlaLys: 5.458 ± 0.998
7.137AlaLeu: 7.137 ± 1.858
1.679AlaMet: 1.679 ± 0.82
4.618AlaAsn: 4.618 ± 1.214
2.939AlaPro: 2.939 ± 2.489
2.519AlaGln: 2.519 ± 0.838
3.359AlaArg: 3.359 ± 0.935
6.717AlaSer: 6.717 ± 3.801
3.778AlaThr: 3.778 ± 0.915
5.038AlaVal: 5.038 ± 2.339
0.42AlaTrp: 0.42 ± 0.205
4.618AlaTyr: 4.618 ± 1.578
0.0AlaXaa: 0.0 ± 0.0
Cys
0.42CysAla: 0.42 ± 0.894
0.0CysCys: 0.0 ± 0.0
0.84CysAsp: 0.84 ± 0.613
1.259CysGlu: 1.259 ± 0.563
0.42CysPhe: 0.42 ± 0.72
0.84CysGly: 0.84 ± 0.613
0.0CysHis: 0.0 ± 0.0
0.42CysIle: 0.42 ± 0.205
1.259CysLys: 1.259 ± 0.615
2.519CysLeu: 2.519 ± 1.321
0.0CysMet: 0.0 ± 0.0
0.84CysAsn: 0.84 ± 0.859
0.84CysPro: 0.84 ± 0.41
1.679CysGln: 1.679 ± 0.82
2.099CysArg: 2.099 ± 0.816
2.519CysSer: 2.519 ± 0.492
0.84CysThr: 0.84 ± 0.41
2.519CysVal: 2.519 ± 1.583
0.0CysTrp: 0.0 ± 0.0
1.259CysTyr: 1.259 ± 1.251
0.0CysXaa: 0.0 ± 0.0
Asp
2.939AspAla: 2.939 ± 1.765
1.259AspCys: 1.259 ± 0.791
2.519AspAsp: 2.519 ± 1.231
3.778AspGlu: 3.778 ± 0.776
2.519AspPhe: 2.519 ± 0.862
1.259AspGly: 1.259 ± 0.794
1.259AspHis: 1.259 ± 0.563
1.679AspIle: 1.679 ± 0.82
2.519AspLys: 2.519 ± 1.156
5.458AspLeu: 5.458 ± 1.503
2.099AspMet: 2.099 ± 0.56
2.099AspAsn: 2.099 ± 0.816
2.939AspPro: 2.939 ± 1.766
1.679AspGln: 1.679 ± 0.82
1.679AspArg: 1.679 ± 0.82
4.618AspSer: 4.618 ± 0.898
1.679AspThr: 1.679 ± 0.82
2.939AspVal: 2.939 ± 1.183
1.259AspTrp: 1.259 ± 0.861
1.679AspTyr: 1.679 ± 1.336
0.0AspXaa: 0.0 ± 0.0
Glu
4.618GluAla: 4.618 ± 1.123
1.679GluCys: 1.679 ± 0.585
3.359GluAsp: 3.359 ± 0.631
2.099GluGlu: 2.099 ± 1.929
2.099GluPhe: 2.099 ± 0.672
2.939GluGly: 2.939 ± 1.024
0.84GluHis: 0.84 ± 0.41
2.519GluIle: 2.519 ± 2.02
3.778GluLys: 3.778 ± 1.244
8.396GluLeu: 8.396 ± 2.898
0.42GluMet: 0.42 ± 0.205
3.359GluAsn: 3.359 ± 1.134
5.038GluPro: 5.038 ± 1.34
1.679GluGln: 1.679 ± 0.838
3.359GluArg: 3.359 ± 1.3
4.618GluSer: 4.618 ± 1.123
2.099GluThr: 2.099 ± 0.723
6.717GluVal: 6.717 ± 0.994
0.84GluTrp: 0.84 ± 0.41
1.679GluTyr: 1.679 ± 2.037
0.0GluXaa: 0.0 ± 0.0
Phe
3.778PheAla: 3.778 ± 2.674
2.099PheCys: 2.099 ± 0.723
4.618PheAsp: 4.618 ± 1.257
2.099PheGlu: 2.099 ± 0.672
1.679PhePhe: 1.679 ± 0.622
1.259PheGly: 1.259 ± 0.794
2.519PheHis: 2.519 ± 0.944
3.778PheIle: 3.778 ± 1.322
0.84PheLys: 0.84 ± 0.605
4.198PheLeu: 4.198 ± 0.943
0.42PheMet: 0.42 ± 0.205
1.259PheAsn: 1.259 ± 0.615
1.679PhePro: 1.679 ± 0.585
2.099PheGln: 2.099 ± 0.672
1.259PheArg: 1.259 ± 0.615
2.099PheSer: 2.099 ± 1.989
2.099PheThr: 2.099 ± 0.672
1.679PheVal: 1.679 ± 0.82
0.42PheTrp: 0.42 ± 0.205
0.84PheTyr: 0.84 ± 0.929
0.0PheXaa: 0.0 ± 0.0
Gly
4.198GlyAla: 4.198 ± 0.987
1.679GlyCys: 1.679 ± 0.585
2.939GlyAsp: 2.939 ± 1.019
0.84GlyGlu: 0.84 ± 0.41
3.359GlyPhe: 3.359 ± 0.696
1.679GlyGly: 1.679 ± 0.991
1.259GlyHis: 1.259 ± 1.118
2.519GlyIle: 2.519 ± 1.071
3.359GlyLys: 3.359 ± 2.242
2.939GlyLeu: 2.939 ± 1.824
0.84GlyMet: 0.84 ± 0.41
1.259GlyAsn: 1.259 ± 0.615
2.099GlyPro: 2.099 ± 1.025
2.519GlyGln: 2.519 ± 1.549
1.259GlyArg: 1.259 ± 0.578
0.42GlySer: 0.42 ± 0.205
2.519GlyThr: 2.519 ± 1.189
2.099GlyVal: 2.099 ± 0.723
0.0GlyTrp: 0.0 ± 0.0
1.259GlyTyr: 1.259 ± 0.578
0.0GlyXaa: 0.0 ± 0.0
His
2.519HisAla: 2.519 ± 0.862
0.42HisCys: 0.42 ± 0.205
0.42HisAsp: 0.42 ± 0.205
1.259HisGlu: 1.259 ± 0.563
0.84HisPhe: 0.84 ± 0.41
1.679HisGly: 1.679 ± 0.622
1.679HisHis: 1.679 ± 0.82
3.359HisIle: 3.359 ± 1.01
2.099HisLys: 2.099 ± 1.243
4.198HisLeu: 4.198 ± 1.494
0.0HisMet: 0.0 ± 0.0
1.259HisAsn: 1.259 ± 0.791
2.099HisPro: 2.099 ± 0.833
2.519HisGln: 2.519 ± 0.841
0.42HisArg: 0.42 ± 0.205
0.84HisSer: 0.84 ± 0.859
2.099HisThr: 2.099 ± 1.025
1.259HisVal: 1.259 ± 0.615
0.42HisTrp: 0.42 ± 0.205
1.259HisTyr: 1.259 ± 1.878
0.0HisXaa: 0.0 ± 0.0
Ile
6.297IleAla: 6.297 ± 1.823
0.42IleCys: 0.42 ± 0.72
2.099IleAsp: 2.099 ± 1.166
3.778IleGlu: 3.778 ± 0.776
4.198IlePhe: 4.198 ± 1.235
1.679IleGly: 1.679 ± 1.395
2.099IleHis: 2.099 ± 1.597
1.679IleIle: 1.679 ± 1.047
4.618IleLys: 4.618 ± 1.696
3.359IleLeu: 3.359 ± 1.974
1.259IleMet: 1.259 ± 1.008
3.778IleAsn: 3.778 ± 1.458
2.939IlePro: 2.939 ± 0.998
1.259IleGln: 1.259 ± 0.791
2.519IleArg: 2.519 ± 0.9
4.618IleSer: 4.618 ± 1.035
2.519IleThr: 2.519 ± 0.875
6.297IleVal: 6.297 ± 3.011
0.0IleTrp: 0.0 ± 0.0
1.259IleTyr: 1.259 ± 1.155
0.0IleXaa: 0.0 ± 0.0
Lys
4.198LysAla: 4.198 ± 0.943
0.84LysCys: 0.84 ± 0.613
4.198LysAsp: 4.198 ± 1.632
5.038LysGlu: 5.038 ± 1.099
1.259LysPhe: 1.259 ± 0.799
2.519LysGly: 2.519 ± 0.838
1.259LysHis: 1.259 ± 0.563
5.458LysIle: 5.458 ± 1.342
7.137LysLys: 7.137 ± 2.579
6.717LysLeu: 6.717 ± 2.032
1.259LysMet: 1.259 ± 0.861
3.359LysAsn: 3.359 ± 1.199
2.519LysPro: 2.519 ± 0.804
3.359LysGln: 3.359 ± 1.199
3.359LysArg: 3.359 ± 1.641
4.198LysSer: 4.198 ± 1.678
6.297LysThr: 6.297 ± 2.183
4.198LysVal: 4.198 ± 1.654
0.42LysTrp: 0.42 ± 0.694
0.42LysTyr: 0.42 ± 0.205
0.0LysXaa: 0.0 ± 0.0
Leu
7.137LeuAla: 7.137 ± 1.371
0.42LeuCys: 0.42 ± 1.035
5.458LeuAsp: 5.458 ± 2.242
5.877LeuGlu: 5.877 ± 1.698
3.778LeuPhe: 3.778 ± 0.915
5.458LeuGly: 5.458 ± 1.01
1.259LeuHis: 1.259 ± 0.578
4.618LeuIle: 4.618 ± 0.769
9.656LeuLys: 9.656 ± 2.241
9.236LeuLeu: 9.236 ± 3.475
3.359LeuMet: 3.359 ± 1.739
4.198LeuAsn: 4.198 ± 0.943
6.297LeuPro: 6.297 ± 1.764
4.618LeuGln: 4.618 ± 0.952
6.297LeuArg: 6.297 ± 1.671
7.137LeuSer: 7.137 ± 0.684
5.038LeuThr: 5.038 ± 1.371
5.038LeuVal: 5.038 ± 1.822
2.099LeuTrp: 2.099 ± 0.833
2.939LeuTyr: 2.939 ± 0.816
0.0LeuXaa: 0.0 ± 0.0
Met
3.359MetAla: 3.359 ± 1.738
0.42MetCys: 0.42 ± 0.894
0.0MetAsp: 0.0 ± 0.0
1.679MetGlu: 1.679 ± 0.585
0.42MetPhe: 0.42 ± 0.205
0.42MetGly: 0.42 ± 0.205
0.0MetHis: 0.0 ± 0.0
1.679MetIle: 1.679 ± 0.82
0.0MetLys: 0.0 ± 0.0
2.939MetLeu: 2.939 ± 1.024
0.0MetMet: 0.0 ± 0.0
1.679MetAsn: 1.679 ± 0.622
1.259MetPro: 1.259 ± 1.503
0.84MetGln: 0.84 ± 0.41
0.84MetArg: 0.84 ± 0.41
1.259MetSer: 1.259 ± 0.861
0.84MetThr: 0.84 ± 0.929
1.259MetVal: 1.259 ± 0.578
0.0MetTrp: 0.0 ± 0.0
0.42MetTyr: 0.42 ± 0.894
0.0MetXaa: 0.0 ± 0.0
Asn
4.198AsnAla: 4.198 ± 2.051
2.519AsnCys: 2.519 ± 0.999
2.099AsnAsp: 2.099 ± 1.025
2.099AsnGlu: 2.099 ± 0.723
1.259AsnPhe: 1.259 ± 0.563
0.84AsnGly: 0.84 ± 0.41
3.778AsnHis: 3.778 ± 0.915
1.259AsnIle: 1.259 ± 0.791
3.359AsnLys: 3.359 ± 0.979
4.618AsnLeu: 4.618 ± 1.578
0.42AsnMet: 0.42 ± 0.812
3.359AsnAsn: 3.359 ± 1.784
2.099AsnPro: 2.099 ± 1.025
1.679AsnGln: 1.679 ± 0.82
2.519AsnArg: 2.519 ± 0.937
3.778AsnSer: 3.778 ± 1.851
2.099AsnThr: 2.099 ± 0.723
2.519AsnVal: 2.519 ± 0.9
1.679AsnTrp: 1.679 ± 0.65
4.198AsnTyr: 4.198 ± 1.272
0.0AsnXaa: 0.0 ± 0.0
Pro
5.458ProAla: 5.458 ± 3.575
0.42ProCys: 0.42 ± 0.894
1.679ProAsp: 1.679 ± 0.82
2.519ProGlu: 2.519 ± 1.231
1.679ProPhe: 1.679 ± 0.778
2.519ProGly: 2.519 ± 0.841
0.84ProHis: 0.84 ± 0.613
4.618ProIle: 4.618 ± 2.275
4.618ProLys: 4.618 ± 1.214
1.259ProLeu: 1.259 ± 1.251
0.84ProMet: 0.84 ± 0.726
2.939ProAsn: 2.939 ± 1.594
2.099ProPro: 2.099 ± 1.516
3.359ProGln: 3.359 ± 2.228
2.519ProArg: 2.519 ± 0.838
4.198ProSer: 4.198 ± 2.017
5.038ProThr: 5.038 ± 1.865
2.519ProVal: 2.519 ± 1.231
0.42ProTrp: 0.42 ± 0.205
2.099ProTyr: 2.099 ± 0.672
0.0ProXaa: 0.0 ± 0.0
Gln
1.679GlnAla: 1.679 ± 1.121
0.42GlnCys: 0.42 ± 0.205
0.84GlnAsp: 0.84 ± 0.41
4.198GlnGlu: 4.198 ± 0.943
2.099GlnPhe: 2.099 ± 1.887
1.259GlnGly: 1.259 ± 0.563
1.679GlnHis: 1.679 ± 0.82
2.939GlnIle: 2.939 ± 0.961
2.939GlnLys: 2.939 ± 1.441
3.359GlnLeu: 3.359 ± 0.935
1.259GlnMet: 1.259 ± 0.691
2.099GlnAsn: 2.099 ± 1.277
2.519GlnPro: 2.519 ± 1.491
0.84GlnGln: 0.84 ± 0.41
2.519GlnArg: 2.519 ± 1.231
4.198GlnSer: 4.198 ± 1.22
2.099GlnThr: 2.099 ± 1.158
2.939GlnVal: 2.939 ± 1.282
2.099GlnTrp: 2.099 ± 0.723
0.42GlnTyr: 0.42 ± 0.72
0.0GlnXaa: 0.0 ± 0.0
Arg
2.939ArgAla: 2.939 ± 1.437
0.42ArgCys: 0.42 ± 0.205
2.939ArgAsp: 2.939 ± 1.436
3.778ArgGlu: 3.778 ± 0.965
4.618ArgPhe: 4.618 ± 1.16
1.259ArgGly: 1.259 ± 0.563
1.259ArgHis: 1.259 ± 0.578
0.42ArgIle: 0.42 ± 0.205
4.618ArgLys: 4.618 ± 1.21
5.038ArgLeu: 5.038 ± 0.837
0.42ArgMet: 0.42 ± 0.205
2.939ArgAsn: 2.939 ± 1.13
1.679ArgPro: 1.679 ± 0.585
2.939ArgGln: 2.939 ± 0.858
2.939ArgArg: 2.939 ± 0.961
3.359ArgSer: 3.359 ± 1.243
2.099ArgThr: 2.099 ± 1.96
2.099ArgVal: 2.099 ± 0.723
0.0ArgTrp: 0.0 ± 0.0
1.259ArgTyr: 1.259 ± 0.791
0.0ArgXaa: 0.0 ± 0.0
Ser
2.939SerAla: 2.939 ± 2.158
2.099SerCys: 2.099 ± 1.929
5.458SerAsp: 5.458 ± 2.155
4.198SerGlu: 4.198 ± 1.686
3.359SerPhe: 3.359 ± 1.348
2.099SerGly: 2.099 ± 1.304
3.359SerHis: 3.359 ± 1.85
4.618SerIle: 4.618 ± 1.954
4.618SerLys: 4.618 ± 1.607
7.557SerLeu: 7.557 ± 1.436
1.259SerMet: 1.259 ± 0.542
3.359SerAsn: 3.359 ± 0.843
3.359SerPro: 3.359 ± 2.421
4.198SerGln: 4.198 ± 1.874
4.198SerArg: 4.198 ± 2.597
5.458SerSer: 5.458 ± 4.166
5.458SerThr: 5.458 ± 1.87
4.198SerVal: 4.198 ± 1.235
1.679SerTrp: 1.679 ± 0.82
1.679SerTyr: 1.679 ± 0.622
0.0SerXaa: 0.0 ± 0.0
Thr
2.939ThrAla: 2.939 ± 0.816
1.259ThrCys: 1.259 ± 0.794
1.679ThrAsp: 1.679 ± 1.366
5.458ThrGlu: 5.458 ± 1.468
1.679ThrPhe: 1.679 ± 0.82
2.939ThrGly: 2.939 ± 2.122
2.939ThrHis: 2.939 ± 1.436
3.359ThrIle: 3.359 ± 0.843
1.259ThrLys: 1.259 ± 0.794
5.458ThrLeu: 5.458 ± 1.503
1.259ThrMet: 1.259 ± 0.861
1.679ThrAsn: 1.679 ± 0.838
3.778ThrPro: 3.778 ± 1.097
1.679ThrGln: 1.679 ± 0.82
1.679ThrArg: 1.679 ± 0.838
5.458ThrSer: 5.458 ± 2.159
4.618ThrThr: 4.618 ± 1.344
5.458ThrVal: 5.458 ± 0.825
0.42ThrTrp: 0.42 ± 0.205
1.259ThrTyr: 1.259 ± 0.615
0.0ThrXaa: 0.0 ± 0.0
Val
6.297ValAla: 6.297 ± 2.684
2.519ValCys: 2.519 ± 1.588
3.778ValAsp: 3.778 ± 1.333
4.618ValGlu: 4.618 ± 1.696
0.84ValPhe: 0.84 ± 0.613
1.679ValGly: 1.679 ± 0.991
0.84ValHis: 0.84 ± 0.41
3.778ValIle: 3.778 ± 1.139
4.198ValLys: 4.198 ± 1.073
10.076ValLeu: 10.076 ± 5.02
0.84ValMet: 0.84 ± 0.41
5.038ValAsn: 5.038 ± 1.997
3.359ValPro: 3.359 ± 1.134
1.259ValGln: 1.259 ± 0.799
2.939ValArg: 2.939 ± 1.755
2.939ValSer: 2.939 ± 0.826
2.939ValThr: 2.939 ± 1.044
5.038ValVal: 5.038 ± 1.429
0.42ValTrp: 0.42 ± 0.694
2.519ValTyr: 2.519 ± 1.231
0.0ValXaa: 0.0 ± 0.0
Trp
2.939TrpAla: 2.939 ± 1.183
0.0TrpCys: 0.0 ± 0.0
0.42TrpAsp: 0.42 ± 0.205
0.42TrpGlu: 0.42 ± 0.205
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.42TrpHis: 0.42 ± 0.205
0.84TrpIle: 0.84 ± 0.969
0.42TrpLys: 0.42 ± 0.205
1.259TrpLeu: 1.259 ± 0.615
0.42TrpMet: 0.42 ± 0.205
0.84TrpAsn: 0.84 ± 0.605
0.84TrpPro: 0.84 ± 1.607
0.0TrpGln: 0.0 ± 0.0
0.42TrpArg: 0.42 ± 0.205
1.679TrpSer: 1.679 ± 0.82
0.42TrpThr: 0.42 ± 0.205
1.259TrpVal: 1.259 ± 0.578
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.198TyrAla: 4.198 ± 0.939
0.84TyrCys: 0.84 ± 0.41
0.84TyrAsp: 0.84 ± 0.41
1.259TyrGlu: 1.259 ± 0.578
0.84TyrPhe: 0.84 ± 0.929
1.679TyrGly: 1.679 ± 1.121
1.259TyrHis: 1.259 ± 0.791
1.679TyrIle: 1.679 ± 1.225
1.259TyrLys: 1.259 ± 1.118
4.198TyrLeu: 4.198 ± 1.22
0.84TyrMet: 0.84 ± 0.41
0.42TyrAsn: 0.42 ± 0.694
1.679TyrPro: 1.679 ± 1.02
1.679TyrGln: 1.679 ± 2.037
0.84TyrArg: 0.84 ± 0.819
5.038TyrSer: 5.038 ± 1.76
1.679TyrThr: 1.679 ± 0.778
0.84TyrVal: 0.84 ± 0.859
0.0TyrTrp: 0.0 ± 0.0
2.939TyrTyr: 2.939 ± 0.826
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2383 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski