Amino acid dipepetide frequency for Hubei sobemo-like virus 15

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.528AlaAla: 13.528 ± 6.775
1.041AlaCys: 1.041 ± 0.646
5.203AlaAsp: 5.203 ± 1.61
3.122AlaGlu: 3.122 ± 0.319
2.081AlaPhe: 2.081 ± 1.291
10.406AlaGly: 10.406 ± 0.015
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
4.162AlaLys: 4.162 ± 0.965
6.243AlaLeu: 6.243 ± 2.597
0.0AlaMet: 0.0 ± 0.0
1.041AlaAsn: 1.041 ± 0.972
2.081AlaPro: 2.081 ± 0.327
3.122AlaGln: 3.122 ± 1.937
6.243AlaArg: 6.243 ± 0.638
4.162AlaSer: 4.162 ± 0.653
3.122AlaThr: 3.122 ± 0.319
9.365AlaVal: 9.365 ± 0.957
4.162AlaTrp: 4.162 ± 0.653
4.162AlaTyr: 4.162 ± 0.965
0.0AlaXaa: 0.0 ± 0.0
Cys
1.041CysAla: 1.041 ± 0.646
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.041CysGlu: 1.041 ± 0.972
3.122CysPhe: 3.122 ± 1.299
1.041CysGly: 1.041 ± 0.972
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.081CysLeu: 2.081 ± 0.327
2.081CysMet: 2.081 ± 0.327
1.041CysAsn: 1.041 ± 0.972
0.0CysPro: 0.0 ± 0.0
2.081CysGln: 2.081 ± 0.327
0.0CysArg: 0.0 ± 0.0
2.081CysSer: 2.081 ± 1.291
0.0CysThr: 0.0 ± 0.0
1.041CysVal: 1.041 ± 0.972
1.041CysTrp: 1.041 ± 0.972
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.162AspAla: 4.162 ± 0.653
1.041AspCys: 1.041 ± 0.972
3.122AspAsp: 3.122 ± 1.299
6.243AspGlu: 6.243 ± 0.98
3.122AspPhe: 3.122 ± 1.299
4.162AspGly: 4.162 ± 2.271
1.041AspHis: 1.041 ± 0.646
0.0AspIle: 0.0 ± 0.0
2.081AspLys: 2.081 ± 0.327
3.122AspLeu: 3.122 ± 0.319
1.041AspMet: 1.041 ± 0.646
1.041AspAsn: 1.041 ± 0.646
4.162AspPro: 4.162 ± 0.653
2.081AspGln: 2.081 ± 1.944
5.203AspArg: 5.203 ± 0.008
2.081AspSer: 2.081 ± 1.944
4.162AspThr: 4.162 ± 3.889
3.122AspVal: 3.122 ± 1.937
1.041AspTrp: 1.041 ± 0.972
1.041AspTyr: 1.041 ± 0.972
0.0AspXaa: 0.0 ± 0.0
Glu
4.162GluAla: 4.162 ± 2.271
0.0GluCys: 0.0 ± 0.0
4.162GluAsp: 4.162 ± 2.271
5.203GluGlu: 5.203 ± 0.008
2.081GluPhe: 2.081 ± 0.327
6.243GluGly: 6.243 ± 2.256
1.041GluHis: 1.041 ± 0.646
4.162GluIle: 4.162 ± 0.653
0.0GluLys: 0.0 ± 0.0
5.203GluLeu: 5.203 ± 1.61
3.122GluMet: 3.122 ± 0.896
1.041GluAsn: 1.041 ± 0.646
4.162GluPro: 4.162 ± 2.271
3.122GluGln: 3.122 ± 0.319
8.325GluArg: 8.325 ± 0.311
4.162GluSer: 4.162 ± 2.582
3.122GluThr: 3.122 ± 0.319
2.081GluVal: 2.081 ± 0.327
1.041GluTrp: 1.041 ± 0.972
1.041GluTyr: 1.041 ± 0.972
0.0GluXaa: 0.0 ± 0.0
Phe
3.122PheAla: 3.122 ± 0.319
2.081PheCys: 2.081 ± 1.944
4.162PheAsp: 4.162 ± 2.271
2.081PheGlu: 2.081 ± 1.944
2.081PhePhe: 2.081 ± 1.291
4.162PheGly: 4.162 ± 0.965
1.041PheHis: 1.041 ± 0.646
0.0PheIle: 0.0 ± 0.0
0.0PheLys: 0.0 ± 0.0
5.203PheLeu: 5.203 ± 1.625
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.041PhePro: 1.041 ± 0.646
4.162PheGln: 4.162 ± 0.965
2.081PheArg: 2.081 ± 0.327
1.041PheSer: 1.041 ± 0.972
0.0PheThr: 0.0 ± 0.0
3.122PheVal: 3.122 ± 2.916
1.041PheTrp: 1.041 ± 0.646
2.081PheTyr: 2.081 ± 0.327
0.0PheXaa: 0.0 ± 0.0
Gly
6.243GlyAla: 6.243 ± 0.638
6.243GlyCys: 6.243 ± 2.597
6.243GlyAsp: 6.243 ± 0.98
2.081GlyGlu: 2.081 ± 1.291
4.162GlyPhe: 4.162 ± 0.965
4.162GlyGly: 4.162 ± 2.271
2.081GlyHis: 2.081 ± 1.944
1.041GlyIle: 1.041 ± 0.972
5.203GlyLys: 5.203 ± 1.625
4.162GlyLeu: 4.162 ± 0.653
1.041GlyMet: 1.041 ± 0.646
2.081GlyAsn: 2.081 ± 0.327
1.041GlyPro: 1.041 ± 0.646
6.243GlyGln: 6.243 ± 3.873
5.203GlyArg: 5.203 ± 1.625
6.243GlySer: 6.243 ± 2.256
2.081GlyThr: 2.081 ± 1.291
7.284GlyVal: 7.284 ± 2.901
1.041GlyTrp: 1.041 ± 0.972
6.243GlyTyr: 6.243 ± 0.638
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
2.081HisCys: 2.081 ± 0.327
1.041HisAsp: 1.041 ± 0.646
0.0HisGlu: 0.0 ± 0.0
1.041HisPhe: 1.041 ± 0.972
1.041HisGly: 1.041 ± 0.646
1.041HisHis: 1.041 ± 0.972
3.122HisIle: 3.122 ± 2.916
1.041HisLys: 1.041 ± 0.972
4.162HisLeu: 4.162 ± 0.653
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.041HisPro: 1.041 ± 0.646
0.0HisGln: 0.0 ± 0.0
1.041HisArg: 1.041 ± 0.646
0.0HisSer: 0.0 ± 0.0
3.122HisThr: 3.122 ± 0.319
2.081HisVal: 2.081 ± 1.291
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.122IleAla: 3.122 ± 1.299
0.0IleCys: 0.0 ± 0.0
2.081IleAsp: 2.081 ± 1.944
2.081IleGlu: 2.081 ± 0.327
2.081IlePhe: 2.081 ± 1.944
2.081IleGly: 2.081 ± 1.944
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
1.041IleLys: 1.041 ± 0.972
3.122IleLeu: 3.122 ± 1.937
2.081IleMet: 2.081 ± 0.327
1.041IleAsn: 1.041 ± 0.972
2.081IlePro: 2.081 ± 1.291
2.081IleGln: 2.081 ± 0.327
2.081IleArg: 2.081 ± 1.944
1.041IleSer: 1.041 ± 0.972
3.122IleThr: 3.122 ± 0.319
2.081IleVal: 2.081 ± 1.291
1.041IleTrp: 1.041 ± 0.646
1.041IleTyr: 1.041 ± 0.972
0.0IleXaa: 0.0 ± 0.0
Lys
1.041LysAla: 1.041 ± 0.646
1.041LysCys: 1.041 ± 0.972
2.081LysAsp: 2.081 ± 1.291
2.081LysGlu: 2.081 ± 1.291
1.041LysPhe: 1.041 ± 0.646
3.122LysGly: 3.122 ± 0.319
1.041LysHis: 1.041 ± 0.972
2.081LysIle: 2.081 ± 0.327
2.081LysLys: 2.081 ± 1.291
1.041LysLeu: 1.041 ± 0.972
1.041LysMet: 1.041 ± 0.972
2.081LysAsn: 2.081 ± 0.327
2.081LysPro: 2.081 ± 1.291
5.203LysGln: 5.203 ± 1.625
4.162LysArg: 4.162 ± 0.653
3.122LysSer: 3.122 ± 0.319
2.081LysThr: 2.081 ± 1.291
3.122LysVal: 3.122 ± 0.319
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.325LeuAla: 8.325 ± 3.547
1.041LeuCys: 1.041 ± 0.646
4.162LeuAsp: 4.162 ± 0.653
10.406LeuGlu: 10.406 ± 6.486
4.162LeuPhe: 4.162 ± 2.271
7.284LeuGly: 7.284 ± 1.284
3.122LeuHis: 3.122 ± 1.299
4.162LeuIle: 4.162 ± 2.271
4.162LeuLys: 4.162 ± 0.965
8.325LeuLeu: 8.325 ± 1.306
0.0LeuMet: 0.0 ± 0.0
4.162LeuAsn: 4.162 ± 0.965
2.081LeuPro: 2.081 ± 0.327
4.162LeuGln: 4.162 ± 0.965
6.243LeuArg: 6.243 ± 0.638
4.162LeuSer: 4.162 ± 0.653
2.081LeuThr: 2.081 ± 1.944
7.284LeuVal: 7.284 ± 0.334
2.081LeuTrp: 2.081 ± 0.327
2.081LeuTyr: 2.081 ± 0.327
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
2.081MetAsp: 2.081 ± 0.327
1.041MetGlu: 1.041 ± 0.646
0.0MetPhe: 0.0 ± 0.0
3.122MetGly: 3.122 ± 0.319
1.041MetHis: 1.041 ± 0.646
2.081MetIle: 2.081 ± 1.944
4.162MetLys: 4.162 ± 0.965
1.041MetLeu: 1.041 ± 0.646
0.0MetMet: 0.0 ± 0.0
1.041MetAsn: 1.041 ± 0.646
2.081MetPro: 2.081 ± 1.291
1.041MetGln: 1.041 ± 0.972
2.081MetArg: 2.081 ± 1.944
2.081MetSer: 2.081 ± 1.291
3.122MetThr: 3.122 ± 0.319
4.162MetVal: 4.162 ± 0.965
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.081AsnAla: 2.081 ± 0.327
1.041AsnCys: 1.041 ± 0.646
1.041AsnAsp: 1.041 ± 0.646
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
1.041AsnIle: 1.041 ± 0.646
3.122AsnLys: 3.122 ± 0.319
3.122AsnLeu: 3.122 ± 1.299
2.081AsnMet: 2.081 ± 0.327
0.0AsnAsn: 0.0 ± 0.0
0.0AsnPro: 0.0 ± 0.0
2.081AsnGln: 2.081 ± 0.327
1.041AsnArg: 1.041 ± 0.646
1.041AsnSer: 1.041 ± 0.972
1.041AsnThr: 1.041 ± 0.646
2.081AsnVal: 2.081 ± 1.291
1.041AsnTrp: 1.041 ± 0.646
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.122ProAla: 3.122 ± 1.299
0.0ProCys: 0.0 ± 0.0
1.041ProAsp: 1.041 ± 0.646
5.203ProGlu: 5.203 ± 3.228
2.081ProPhe: 2.081 ± 0.327
5.203ProGly: 5.203 ± 1.61
4.162ProHis: 4.162 ± 0.653
2.081ProIle: 2.081 ± 1.944
0.0ProLys: 0.0 ± 0.0
2.081ProLeu: 2.081 ± 1.291
1.041ProMet: 1.041 ± 1.042
2.081ProAsn: 2.081 ± 0.327
3.122ProPro: 3.122 ± 1.937
0.0ProGln: 0.0 ± 0.0
3.122ProArg: 3.122 ± 0.319
1.041ProSer: 1.041 ± 0.646
1.041ProThr: 1.041 ± 0.646
3.122ProVal: 3.122 ± 0.319
1.041ProTrp: 1.041 ± 0.972
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.122GlnAla: 3.122 ± 0.319
0.0GlnCys: 0.0 ± 0.0
4.162GlnAsp: 4.162 ± 2.271
4.162GlnGlu: 4.162 ± 0.653
1.041GlnPhe: 1.041 ± 0.972
4.162GlnGly: 4.162 ± 0.965
2.081GlnHis: 2.081 ± 0.327
0.0GlnIle: 0.0 ± 0.0
2.081GlnLys: 2.081 ± 1.291
5.203GlnLeu: 5.203 ± 3.243
3.122GlnMet: 3.122 ± 0.319
0.0GlnAsn: 0.0 ± 0.0
3.122GlnPro: 3.122 ± 0.319
2.081GlnGln: 2.081 ± 0.327
6.243GlnArg: 6.243 ± 0.638
6.243GlnSer: 6.243 ± 2.256
3.122GlnThr: 3.122 ± 1.937
3.122GlnVal: 3.122 ± 0.319
1.041GlnTrp: 1.041 ± 0.646
1.041GlnTyr: 1.041 ± 0.646
0.0GlnXaa: 0.0 ± 0.0
Arg
6.243ArgAla: 6.243 ± 0.638
1.041ArgCys: 1.041 ± 0.972
1.041ArgAsp: 1.041 ± 0.646
4.162ArgGlu: 4.162 ± 0.965
4.162ArgPhe: 4.162 ± 2.271
4.162ArgGly: 4.162 ± 2.271
0.0ArgHis: 0.0 ± 0.0
4.162ArgIle: 4.162 ± 0.965
1.041ArgLys: 1.041 ± 0.646
10.406ArgLeu: 10.406 ± 3.251
4.162ArgMet: 4.162 ± 0.965
2.081ArgAsn: 2.081 ± 1.291
3.122ArgPro: 3.122 ± 0.319
5.203ArgGln: 5.203 ± 1.625
6.243ArgArg: 6.243 ± 0.638
5.203ArgSer: 5.203 ± 1.625
3.122ArgThr: 3.122 ± 1.937
4.162ArgVal: 4.162 ± 0.653
2.081ArgTrp: 2.081 ± 0.327
4.162ArgTyr: 4.162 ± 0.653
0.0ArgXaa: 0.0 ± 0.0
Ser
9.365SerAla: 9.365 ± 2.575
0.0SerCys: 0.0 ± 0.0
3.122SerAsp: 3.122 ± 1.299
5.203SerGlu: 5.203 ± 0.008
0.0SerPhe: 0.0 ± 0.0
6.243SerGly: 6.243 ± 2.256
0.0SerHis: 0.0 ± 0.0
3.122SerIle: 3.122 ± 1.937
4.162SerLys: 4.162 ± 0.653
5.203SerLeu: 5.203 ± 1.625
2.081SerMet: 2.081 ± 0.327
0.0SerAsn: 0.0 ± 0.0
5.203SerPro: 5.203 ± 1.61
5.203SerGln: 5.203 ± 1.61
3.122SerArg: 3.122 ± 1.299
7.284SerSer: 7.284 ± 2.901
3.122SerThr: 3.122 ± 0.319
4.162SerVal: 4.162 ± 0.653
1.041SerTrp: 1.041 ± 0.646
4.162SerTyr: 4.162 ± 0.965
0.0SerXaa: 0.0 ± 0.0
Thr
2.081ThrAla: 2.081 ± 1.944
0.0ThrCys: 0.0 ± 0.0
1.041ThrAsp: 1.041 ± 0.972
3.122ThrGlu: 3.122 ± 1.937
3.122ThrPhe: 3.122 ± 0.319
3.122ThrGly: 3.122 ± 0.319
1.041ThrHis: 1.041 ± 0.646
5.203ThrIle: 5.203 ± 1.625
3.122ThrLys: 3.122 ± 0.319
6.243ThrLeu: 6.243 ± 2.256
4.162ThrMet: 4.162 ± 0.965
0.0ThrAsn: 0.0 ± 0.0
2.081ThrPro: 2.081 ± 0.327
1.041ThrGln: 1.041 ± 0.972
0.0ThrArg: 0.0 ± 0.0
5.203ThrSer: 5.203 ± 1.61
2.081ThrThr: 2.081 ± 1.291
3.122ThrVal: 3.122 ± 1.937
1.041ThrTrp: 1.041 ± 0.646
1.041ThrTyr: 1.041 ± 0.646
0.0ThrXaa: 0.0 ± 0.0
Val
10.406ValAla: 10.406 ± 3.22
1.041ValCys: 1.041 ± 0.646
4.162ValAsp: 4.162 ± 3.889
5.203ValGlu: 5.203 ± 0.008
2.081ValPhe: 2.081 ± 0.327
7.284ValGly: 7.284 ± 1.284
1.041ValHis: 1.041 ± 0.646
1.041ValIle: 1.041 ± 0.646
2.081ValLys: 2.081 ± 0.327
7.284ValLeu: 7.284 ± 0.334
1.041ValMet: 1.041 ± 0.646
1.041ValAsn: 1.041 ± 0.646
2.081ValPro: 2.081 ± 0.327
3.122ValGln: 3.122 ± 1.937
6.243ValArg: 6.243 ± 0.98
11.446ValSer: 11.446 ± 0.63
2.081ValThr: 2.081 ± 1.291
9.365ValVal: 9.365 ± 0.957
1.041ValTrp: 1.041 ± 0.646
3.122ValTyr: 3.122 ± 1.937
0.0ValXaa: 0.0 ± 0.0
Trp
1.041TrpAla: 1.041 ± 0.972
0.0TrpCys: 0.0 ± 0.0
2.081TrpAsp: 2.081 ± 0.327
1.041TrpGlu: 1.041 ± 0.972
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.041TrpHis: 1.041 ± 0.646
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
3.122TrpLeu: 3.122 ± 1.299
1.041TrpMet: 1.041 ± 0.646
1.041TrpAsn: 1.041 ± 0.646
1.041TrpPro: 1.041 ± 0.646
1.041TrpGln: 1.041 ± 0.972
2.081TrpArg: 2.081 ± 1.291
2.081TrpSer: 2.081 ± 0.327
2.081TrpThr: 2.081 ± 0.327
3.122TrpVal: 3.122 ± 0.319
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.041TyrAla: 1.041 ± 0.646
0.0TyrCys: 0.0 ± 0.0
1.041TyrAsp: 1.041 ± 0.972
0.0TyrGlu: 0.0 ± 0.0
1.041TyrPhe: 1.041 ± 0.646
3.122TyrGly: 3.122 ± 1.299
1.041TyrHis: 1.041 ± 0.972
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
3.122TyrLeu: 3.122 ± 1.937
0.0TyrMet: 0.0 ± 0.0
1.041TyrAsn: 1.041 ± 0.646
0.0TyrPro: 0.0 ± 0.0
2.081TyrGln: 2.081 ± 0.327
5.203TyrArg: 5.203 ± 1.625
2.081TyrSer: 2.081 ± 1.291
4.162TyrThr: 4.162 ± 0.965
5.203TyrVal: 5.203 ± 0.008
1.041TyrTrp: 1.041 ± 0.646
1.041TyrTyr: 1.041 ± 0.646
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (962 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski