Amino acid dipepetide frequency for Shahe sobemo-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.26AlaAla: 7.26 ± 0.28
2.722AlaCys: 2.722 ± 1.089
6.352AlaAsp: 6.352 ± 2.996
2.722AlaGlu: 2.722 ± 1.64
3.63AlaPhe: 3.63 ± 1.907
3.63AlaGly: 3.63 ± 0.542
0.907AlaHis: 0.907 ± 0.547
2.722AlaIle: 2.722 ± 1.64
4.537AlaLys: 4.537 ± 1.369
12.704AlaLeu: 12.704 ± 0.534
0.907AlaMet: 0.907 ± 0.818
4.537AlaAsn: 4.537 ± 0.004
2.722AlaPro: 2.722 ± 1.089
2.722AlaGln: 2.722 ± 1.64
5.445AlaArg: 5.445 ± 3.28
6.352AlaSer: 6.352 ± 1.631
1.815AlaThr: 1.815 ± 1.636
6.352AlaVal: 6.352 ± 1.098
0.0AlaTrp: 0.0 ± 0.0
1.815AlaTyr: 1.815 ± 0.271
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
3.63CysGly: 3.63 ± 0.542
0.907CysHis: 0.907 ± 0.547
0.907CysIle: 0.907 ± 0.818
0.0CysLys: 0.0 ± 0.0
1.815CysLeu: 1.815 ± 0.271
0.907CysMet: 0.907 ± 0.547
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.907CysGln: 0.907 ± 0.547
0.0CysArg: 0.0 ± 0.0
2.722CysSer: 2.722 ± 0.276
0.907CysThr: 0.907 ± 0.818
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.537AspAla: 4.537 ± 1.369
0.0AspCys: 0.0 ± 0.0
8.167AspAsp: 8.167 ± 0.538
7.26AspGlu: 7.26 ± 1.085
2.722AspPhe: 2.722 ± 2.454
1.815AspGly: 1.815 ± 1.093
1.815AspHis: 1.815 ± 1.093
0.907AspIle: 0.907 ± 0.547
6.352AspLys: 6.352 ± 5.725
3.63AspLeu: 3.63 ± 2.187
0.907AspMet: 0.907 ± 0.547
1.815AspAsn: 1.815 ± 0.271
3.63AspPro: 3.63 ± 0.822
4.537AspGln: 4.537 ± 1.369
6.352AspArg: 6.352 ± 1.098
1.815AspSer: 1.815 ± 1.093
1.815AspThr: 1.815 ± 1.636
3.63AspVal: 3.63 ± 3.271
1.815AspTrp: 1.815 ± 1.636
5.445AspTyr: 5.445 ± 1.916
0.0AspXaa: 0.0 ± 0.0
Glu
7.26GluAla: 7.26 ± 3.009
0.0GluCys: 0.0 ± 0.0
7.26GluAsp: 7.26 ± 1.644
6.352GluGlu: 6.352 ± 0.267
1.815GluPhe: 1.815 ± 1.093
8.167GluGly: 8.167 ± 0.827
0.907GluHis: 0.907 ± 0.818
6.352GluIle: 6.352 ± 0.267
3.63GluLys: 3.63 ± 0.822
9.074GluLeu: 9.074 ± 1.373
1.815GluMet: 1.815 ± 0.271
2.722GluAsn: 2.722 ± 1.64
0.907GluPro: 0.907 ± 0.818
1.815GluGln: 1.815 ± 1.636
3.63GluArg: 3.63 ± 0.822
0.907GluSer: 0.907 ± 0.818
1.815GluThr: 1.815 ± 1.093
0.907GluVal: 0.907 ± 0.818
0.0GluTrp: 0.0 ± 0.0
2.722GluTyr: 2.722 ± 1.089
0.0GluXaa: 0.0 ± 0.0
Phe
1.815PheAla: 1.815 ± 1.636
0.907PheCys: 0.907 ± 0.547
3.63PheAsp: 3.63 ± 1.907
3.63PheGlu: 3.63 ± 1.907
4.537PhePhe: 4.537 ± 1.36
7.26PheGly: 7.26 ± 0.28
0.0PheHis: 0.0 ± 0.0
1.815PheIle: 1.815 ± 0.271
2.722PheLys: 2.722 ± 1.089
2.722PheLeu: 2.722 ± 1.64
0.907PheMet: 0.907 ± 0.818
0.907PheAsn: 0.907 ± 0.818
1.815PhePro: 1.815 ± 0.271
0.907PheGln: 0.907 ± 0.547
0.907PheArg: 0.907 ± 0.547
2.722PheSer: 2.722 ± 1.64
3.63PheThr: 3.63 ± 1.907
1.815PheVal: 1.815 ± 1.093
1.815PheTrp: 1.815 ± 1.093
3.63PheTyr: 3.63 ± 0.822
0.0PheXaa: 0.0 ± 0.0
Gly
7.26GlyAla: 7.26 ± 0.28
2.722GlyCys: 2.722 ± 0.276
4.537GlyAsp: 4.537 ± 0.004
3.63GlyGlu: 3.63 ± 0.822
5.445GlyPhe: 5.445 ± 0.551
7.26GlyGly: 7.26 ± 3.814
0.0GlyHis: 0.0 ± 0.0
1.815GlyIle: 1.815 ± 1.093
5.445GlyLys: 5.445 ± 0.814
7.26GlyLeu: 7.26 ± 1.644
2.722GlyMet: 2.722 ± 1.528
2.722GlyAsn: 2.722 ± 1.64
3.63GlyPro: 3.63 ± 0.822
0.0GlyGln: 0.0 ± 0.0
9.074GlyArg: 9.074 ± 2.72
0.0GlySer: 0.0 ± 0.0
3.63GlyThr: 3.63 ± 0.822
8.167GlyVal: 8.167 ± 2.191
2.722GlyTrp: 2.722 ± 2.454
1.815GlyTyr: 1.815 ± 0.271
0.0GlyXaa: 0.0 ± 0.0
His
3.63HisAla: 3.63 ± 0.822
0.907HisCys: 0.907 ± 0.547
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.815HisPhe: 1.815 ± 0.271
3.63HisGly: 3.63 ± 2.187
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.907HisLys: 0.907 ± 0.547
0.907HisLeu: 0.907 ± 0.547
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
1.815HisGln: 1.815 ± 0.271
1.815HisArg: 1.815 ± 1.636
3.63HisSer: 3.63 ± 2.187
0.907HisThr: 0.907 ± 0.547
1.815HisVal: 1.815 ± 0.271
0.907HisTrp: 0.907 ± 0.818
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.63IleAla: 3.63 ± 0.822
0.0IleCys: 0.0 ± 0.0
0.907IleAsp: 0.907 ± 0.818
2.722IleGlu: 2.722 ± 1.089
1.815IlePhe: 1.815 ± 0.271
0.907IleGly: 0.907 ± 0.547
0.0IleHis: 0.0 ± 0.0
4.537IleIle: 4.537 ± 0.004
1.815IleLys: 1.815 ± 0.271
1.815IleLeu: 1.815 ± 0.271
0.907IleMet: 0.907 ± 0.547
0.907IleAsn: 0.907 ± 0.818
2.722IlePro: 2.722 ± 1.64
0.0IleGln: 0.0 ± 0.0
4.537IleArg: 4.537 ± 1.36
5.445IleSer: 5.445 ± 0.551
2.722IleThr: 2.722 ± 1.089
3.63IleVal: 3.63 ± 0.542
0.0IleTrp: 0.0 ± 0.0
0.907IleTyr: 0.907 ± 0.818
0.0IleXaa: 0.0 ± 0.0
Lys
6.352LysAla: 6.352 ± 1.631
0.0LysCys: 0.0 ± 0.0
1.815LysAsp: 1.815 ± 0.271
5.445LysGlu: 5.445 ± 0.551
0.907LysPhe: 0.907 ± 0.818
2.722LysGly: 2.722 ± 1.089
3.63LysHis: 3.63 ± 3.271
1.815LysIle: 1.815 ± 1.093
4.537LysLys: 4.537 ± 1.36
5.445LysLeu: 5.445 ± 0.551
0.907LysMet: 0.907 ± 0.547
3.63LysAsn: 3.63 ± 0.542
1.815LysPro: 1.815 ± 1.093
1.815LysGln: 1.815 ± 1.093
5.445LysArg: 5.445 ± 0.551
5.445LysSer: 5.445 ± 0.551
4.537LysThr: 4.537 ± 1.36
1.815LysVal: 1.815 ± 1.093
1.815LysTrp: 1.815 ± 1.636
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
9.982LeuAla: 9.982 ± 2.174
0.907LeuCys: 0.907 ± 0.547
4.537LeuAsp: 4.537 ± 2.733
6.352LeuGlu: 6.352 ± 0.267
2.722LeuPhe: 2.722 ± 1.089
8.167LeuGly: 8.167 ± 1.903
2.722LeuHis: 2.722 ± 1.64
1.815LeuIle: 1.815 ± 0.271
4.537LeuLys: 4.537 ± 0.004
8.167LeuLeu: 8.167 ± 2.191
2.722LeuMet: 2.722 ± 0.276
3.63LeuAsn: 3.63 ± 0.822
3.63LeuPro: 3.63 ± 2.187
2.722LeuGln: 2.722 ± 1.089
4.537LeuArg: 4.537 ± 0.004
2.722LeuSer: 2.722 ± 1.64
7.26LeuThr: 7.26 ± 3.009
9.982LeuVal: 9.982 ± 1.92
0.0LeuTrp: 0.0 ± 0.0
0.907LeuTyr: 0.907 ± 0.818
0.0LeuXaa: 0.0 ± 0.0
Met
2.722MetAla: 2.722 ± 1.089
0.0MetCys: 0.0 ± 0.0
0.907MetAsp: 0.907 ± 0.547
3.63MetGlu: 3.63 ± 2.187
0.907MetPhe: 0.907 ± 0.818
2.722MetGly: 2.722 ± 1.089
1.815MetHis: 1.815 ± 1.093
0.0MetIle: 0.0 ± 0.0
0.907MetLys: 0.907 ± 0.818
0.0MetLeu: 0.0 ± 0.0
0.907MetMet: 0.907 ± 0.547
0.907MetAsn: 0.907 ± 0.547
0.907MetPro: 0.907 ± 0.547
1.815MetGln: 1.815 ± 1.636
2.722MetArg: 2.722 ± 0.276
0.0MetSer: 0.0 ± 0.0
1.815MetThr: 1.815 ± 0.271
1.815MetVal: 1.815 ± 0.271
0.0MetTrp: 0.0 ± 0.0
2.722MetTyr: 2.722 ± 0.276
0.0MetXaa: 0.0 ± 0.0
Asn
1.815AsnAla: 1.815 ± 0.271
0.907AsnCys: 0.907 ± 0.547
4.537AsnAsp: 4.537 ± 0.004
0.907AsnGlu: 0.907 ± 0.547
1.815AsnPhe: 1.815 ± 1.093
3.63AsnGly: 3.63 ± 0.542
0.907AsnHis: 0.907 ± 0.547
0.0AsnIle: 0.0 ± 0.0
3.63AsnLys: 3.63 ± 1.907
1.815AsnLeu: 1.815 ± 1.636
1.815AsnMet: 1.815 ± 0.624
0.0AsnAsn: 0.0 ± 0.0
2.722AsnPro: 2.722 ± 0.276
0.907AsnGln: 0.907 ± 0.547
2.722AsnArg: 2.722 ± 0.276
1.815AsnSer: 1.815 ± 0.271
0.0AsnThr: 0.0 ± 0.0
4.537AsnVal: 4.537 ± 2.733
0.0AsnTrp: 0.0 ± 0.0
1.815AsnTyr: 1.815 ± 1.636
0.0AsnXaa: 0.0 ± 0.0
Pro
2.722ProAla: 2.722 ± 1.089
0.0ProCys: 0.0 ± 0.0
4.537ProAsp: 4.537 ± 0.004
3.63ProGlu: 3.63 ± 2.187
0.907ProPhe: 0.907 ± 0.547
4.537ProGly: 4.537 ± 1.369
0.907ProHis: 0.907 ± 0.547
2.722ProIle: 2.722 ± 2.454
1.815ProLys: 1.815 ± 1.093
1.815ProLeu: 1.815 ± 1.093
0.0ProMet: 0.0 ± 0.0
3.63ProAsn: 3.63 ± 3.271
0.0ProPro: 0.0 ± 0.0
1.815ProGln: 1.815 ± 1.093
0.907ProArg: 0.907 ± 0.547
0.907ProSer: 0.907 ± 0.818
1.815ProThr: 1.815 ± 1.636
3.63ProVal: 3.63 ± 0.822
0.907ProTrp: 0.907 ± 0.818
1.815ProTyr: 1.815 ± 0.271
0.0ProXaa: 0.0 ± 0.0
Gln
1.815GlnAla: 1.815 ± 1.093
0.0GlnCys: 0.0 ± 0.0
1.815GlnAsp: 1.815 ± 1.093
3.63GlnGlu: 3.63 ± 2.187
0.0GlnPhe: 0.0 ± 0.0
0.0GlnGly: 0.0 ± 0.0
0.907GlnHis: 0.907 ± 0.818
0.907GlnIle: 0.907 ± 0.547
3.63GlnLys: 3.63 ± 0.822
2.722GlnLeu: 2.722 ± 1.64
1.815GlnMet: 1.815 ± 1.093
1.815GlnAsn: 1.815 ± 1.093
0.907GlnPro: 0.907 ± 0.818
0.907GlnGln: 0.907 ± 0.818
1.815GlnArg: 1.815 ± 0.271
1.815GlnSer: 1.815 ± 0.271
0.907GlnThr: 0.907 ± 0.547
1.815GlnVal: 1.815 ± 1.636
0.0GlnTrp: 0.0 ± 0.0
3.63GlnTyr: 3.63 ± 0.542
0.0GlnXaa: 0.0 ± 0.0
Arg
1.815ArgAla: 1.815 ± 0.271
1.815ArgCys: 1.815 ± 0.271
3.63ArgAsp: 3.63 ± 0.542
3.63ArgGlu: 3.63 ± 1.907
3.63ArgPhe: 3.63 ± 0.542
4.537ArgGly: 4.537 ± 1.369
4.537ArgHis: 4.537 ± 2.733
3.63ArgIle: 3.63 ± 0.542
3.63ArgLys: 3.63 ± 0.822
9.074ArgLeu: 9.074 ± 0.009
0.907ArgMet: 0.907 ± 0.547
1.815ArgAsn: 1.815 ± 0.271
2.722ArgPro: 2.722 ± 1.089
3.63ArgGln: 3.63 ± 0.822
2.722ArgArg: 2.722 ± 0.276
7.26ArgSer: 7.26 ± 1.644
1.815ArgThr: 1.815 ± 0.271
5.445ArgVal: 5.445 ± 2.178
2.722ArgTrp: 2.722 ± 0.276
0.907ArgTyr: 0.907 ± 0.547
0.0ArgXaa: 0.0 ± 0.0
Ser
7.26SerAla: 7.26 ± 3.009
0.0SerCys: 0.0 ± 0.0
7.26SerAsp: 7.26 ± 1.644
5.445SerGlu: 5.445 ± 0.551
2.722SerPhe: 2.722 ± 0.276
7.26SerGly: 7.26 ± 1.644
0.907SerHis: 0.907 ± 0.547
1.815SerIle: 1.815 ± 0.271
0.907SerLys: 0.907 ± 0.547
5.445SerLeu: 5.445 ± 0.551
1.815SerMet: 1.815 ± 1.636
0.907SerAsn: 0.907 ± 0.547
0.907SerPro: 0.907 ± 0.818
0.907SerGln: 0.907 ± 0.547
4.537SerArg: 4.537 ± 1.369
3.63SerSer: 3.63 ± 0.542
2.722SerThr: 2.722 ± 1.089
3.63SerVal: 3.63 ± 3.271
0.907SerTrp: 0.907 ± 0.547
1.815SerTyr: 1.815 ± 1.636
0.0SerXaa: 0.0 ± 0.0
Thr
0.907ThrAla: 0.907 ± 0.547
0.0ThrCys: 0.0 ± 0.0
0.907ThrAsp: 0.907 ± 0.547
2.722ThrGlu: 2.722 ± 0.276
2.722ThrPhe: 2.722 ± 0.276
1.815ThrGly: 1.815 ± 0.271
0.0ThrHis: 0.0 ± 0.0
2.722ThrIle: 2.722 ± 2.454
7.26ThrLys: 7.26 ± 3.009
3.63ThrLeu: 3.63 ± 1.907
2.722ThrMet: 2.722 ± 1.089
1.815ThrAsn: 1.815 ± 1.636
2.722ThrPro: 2.722 ± 0.276
0.907ThrGln: 0.907 ± 0.547
3.63ThrArg: 3.63 ± 3.271
1.815ThrSer: 1.815 ± 0.271
5.445ThrThr: 5.445 ± 1.916
3.63ThrVal: 3.63 ± 0.822
0.0ThrTrp: 0.0 ± 0.0
0.907ThrTyr: 0.907 ± 0.547
0.0ThrXaa: 0.0 ± 0.0
Val
4.537ValAla: 4.537 ± 2.725
0.907ValCys: 0.907 ± 0.818
5.445ValAsp: 5.445 ± 3.543
4.537ValGlu: 4.537 ± 1.369
7.26ValPhe: 7.26 ± 0.28
4.537ValGly: 4.537 ± 1.369
0.907ValHis: 0.907 ± 0.818
3.63ValIle: 3.63 ± 0.542
2.722ValLys: 2.722 ± 1.089
6.352ValLeu: 6.352 ± 1.098
1.815ValMet: 1.815 ± 1.093
2.722ValAsn: 2.722 ± 1.64
2.722ValPro: 2.722 ± 2.454
2.722ValGln: 2.722 ± 1.64
5.445ValArg: 5.445 ± 1.916
6.352ValSer: 6.352 ± 0.267
2.722ValThr: 2.722 ± 1.64
6.352ValVal: 6.352 ± 2.462
0.907ValTrp: 0.907 ± 0.547
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.907TrpAla: 0.907 ± 0.547
0.0TrpCys: 0.0 ± 0.0
0.907TrpAsp: 0.907 ± 0.818
0.0TrpGlu: 0.0 ± 0.0
0.907TrpPhe: 0.907 ± 0.547
0.907TrpGly: 0.907 ± 0.818
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.815TrpLeu: 1.815 ± 1.636
0.907TrpMet: 0.907 ± 0.547
0.0TrpAsn: 0.0 ± 0.0
0.907TrpPro: 0.907 ± 0.818
0.0TrpGln: 0.0 ± 0.0
1.815TrpArg: 1.815 ± 0.271
2.722TrpSer: 2.722 ± 2.454
0.0TrpThr: 0.0 ± 0.0
1.815TrpVal: 1.815 ± 1.093
0.0TrpTrp: 0.0 ± 0.0
0.907TrpTyr: 0.907 ± 0.818
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.63TyrAla: 3.63 ± 1.907
0.907TyrCys: 0.907 ± 0.818
1.815TyrAsp: 1.815 ± 0.271
1.815TyrGlu: 1.815 ± 0.271
1.815TyrPhe: 1.815 ± 1.093
3.63TyrGly: 3.63 ± 1.907
0.907TyrHis: 0.907 ± 0.547
1.815TyrIle: 1.815 ± 0.271
0.907TyrLys: 0.907 ± 0.818
1.815TyrLeu: 1.815 ± 1.093
0.907TyrMet: 0.907 ± 0.547
1.815TyrAsn: 1.815 ± 0.271
3.63TyrPro: 3.63 ± 0.542
0.0TyrGln: 0.0 ± 0.0
1.815TyrArg: 1.815 ± 0.271
2.722TyrSer: 2.722 ± 0.276
0.0TyrThr: 0.0 ± 0.0
1.815TyrVal: 1.815 ± 0.271
0.0TyrTrp: 0.0 ± 0.0
2.722TyrTyr: 2.722 ± 0.276
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1103 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski