Amino acid dipepetide frequency for Tortoise microvirus 21

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.087AlaAla: 5.087 ± 3.77
0.727AlaCys: 0.727 ± 0.645
2.907AlaAsp: 2.907 ± 1.753
5.087AlaGlu: 5.087 ± 1.639
2.907AlaPhe: 2.907 ± 1.681
3.634AlaGly: 3.634 ± 1.257
1.453AlaHis: 1.453 ± 0.685
2.907AlaIle: 2.907 ± 1.11
2.907AlaLys: 2.907 ± 3.463
5.087AlaLeu: 5.087 ± 1.49
2.907AlaMet: 2.907 ± 1.645
2.18AlaAsn: 2.18 ± 1.34
3.634AlaPro: 3.634 ± 1.267
3.634AlaGln: 3.634 ± 1.91
3.634AlaArg: 3.634 ± 1.267
7.267AlaSer: 7.267 ± 3.805
2.907AlaThr: 2.907 ± 1.322
2.907AlaVal: 2.907 ± 0.868
2.18AlaTrp: 2.18 ± 1.175
2.907AlaTyr: 2.907 ± 1.377
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.453CysAsp: 1.453 ± 0.993
0.0CysGlu: 0.0 ± 0.0
0.727CysPhe: 0.727 ± 1.154
2.907CysGly: 2.907 ± 1.23
0.0CysHis: 0.0 ± 0.0
0.727CysIle: 0.727 ± 1.154
1.453CysLys: 1.453 ± 1.052
0.0CysLeu: 0.0 ± 0.0
0.727CysMet: 0.727 ± 0.645
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.727CysArg: 0.727 ± 0.645
0.0CysSer: 0.0 ± 0.0
0.727CysThr: 0.727 ± 0.645
1.453CysVal: 1.453 ± 1.31
0.727CysTrp: 0.727 ± 0.497
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.541AspAla: 6.541 ± 2.577
0.727AspCys: 0.727 ± 0.497
3.634AspAsp: 3.634 ± 0.698
5.087AspGlu: 5.087 ± 1.485
3.634AspPhe: 3.634 ± 1.656
2.18AspGly: 2.18 ± 1.49
2.18AspHis: 2.18 ± 1.16
2.18AspIle: 2.18 ± 1.111
1.453AspLys: 1.453 ± 0.685
5.814AspLeu: 5.814 ± 1.637
2.18AspMet: 2.18 ± 1.012
1.453AspAsn: 1.453 ± 0.617
3.634AspPro: 3.634 ± 4.248
1.453AspGln: 1.453 ± 0.685
3.634AspArg: 3.634 ± 1.468
2.907AspSer: 2.907 ± 1.377
2.18AspThr: 2.18 ± 0.693
2.18AspVal: 2.18 ± 1.558
1.453AspTrp: 1.453 ± 0.902
4.36AspTyr: 4.36 ± 1.239
0.0AspXaa: 0.0 ± 0.0
Glu
5.814GluAla: 5.814 ± 4.465
0.0GluCys: 0.0 ± 0.0
2.907GluAsp: 2.907 ± 0.979
4.36GluGlu: 4.36 ± 3.03
2.18GluPhe: 2.18 ± 1.012
2.907GluGly: 2.907 ± 1.746
0.727GluHis: 0.727 ± 0.497
4.36GluIle: 4.36 ± 1.807
5.087GluLys: 5.087 ± 2.22
7.994GluLeu: 7.994 ± 1.546
1.453GluMet: 1.453 ± 0.685
7.994GluAsn: 7.994 ± 2.147
1.453GluPro: 1.453 ± 1.452
3.634GluGln: 3.634 ± 0.698
2.907GluArg: 2.907 ± 1.268
3.634GluSer: 3.634 ± 1.044
2.907GluThr: 2.907 ± 1.533
7.267GluVal: 7.267 ± 2.225
0.727GluTrp: 0.727 ± 0.645
4.36GluTyr: 4.36 ± 1.831
0.0GluXaa: 0.0 ± 0.0
Phe
1.453PheAla: 1.453 ± 0.836
0.0PheCys: 0.0 ± 0.0
4.36PheAsp: 4.36 ± 1.657
1.453PheGlu: 1.453 ± 1.317
1.453PhePhe: 1.453 ± 0.617
3.634PheGly: 3.634 ± 1.48
0.0PheHis: 0.0 ± 0.0
5.087PheIle: 5.087 ± 1.85
1.453PheLys: 1.453 ± 1.289
2.907PheLeu: 2.907 ± 1.986
2.18PheMet: 2.18 ± 0.988
2.18PheAsn: 2.18 ± 1.227
0.727PhePro: 0.727 ± 1.154
3.634PheGln: 3.634 ± 1.48
1.453PheArg: 1.453 ± 1.052
2.907PheSer: 2.907 ± 2.784
0.727PheThr: 0.727 ± 0.497
2.18PheVal: 2.18 ± 1.49
0.727PheTrp: 0.727 ± 0.497
0.727PheTyr: 0.727 ± 0.984
0.0PheXaa: 0.0 ± 0.0
Gly
5.814GlyAla: 5.814 ± 1.61
0.0GlyCys: 0.0 ± 0.0
2.907GlyAsp: 2.907 ± 0.896
5.087GlyGlu: 5.087 ± 2.633
4.36GlyPhe: 4.36 ± 1.77
2.907GlyGly: 2.907 ± 1.338
0.727GlyHis: 0.727 ± 0.497
3.634GlyIle: 3.634 ± 1.656
4.36GlyLys: 4.36 ± 1.875
5.087GlyLeu: 5.087 ± 2.267
1.453GlyMet: 1.453 ± 0.993
1.453GlyAsn: 1.453 ± 0.993
2.907GlyPro: 2.907 ± 1.11
4.36GlyGln: 4.36 ± 1.739
4.36GlyArg: 4.36 ± 1.858
3.634GlySer: 3.634 ± 1.902
3.634GlyThr: 3.634 ± 2.034
3.634GlyVal: 3.634 ± 1.48
0.0GlyTrp: 0.0 ± 0.0
3.634GlyTyr: 3.634 ± 1.644
0.0GlyXaa: 0.0 ± 0.0
His
0.727HisAla: 0.727 ± 0.645
0.727HisCys: 0.727 ± 1.154
1.453HisAsp: 1.453 ± 1.317
1.453HisGlu: 1.453 ± 0.617
1.453HisPhe: 1.453 ± 0.993
0.727HisGly: 0.727 ± 0.497
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.727HisLys: 0.727 ± 0.645
1.453HisLeu: 1.453 ± 0.617
0.727HisMet: 0.727 ± 0.638
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.727HisArg: 0.727 ± 1.154
1.453HisSer: 1.453 ± 0.685
0.727HisThr: 0.727 ± 0.497
1.453HisVal: 1.453 ± 0.617
0.0HisTrp: 0.0 ± 0.0
2.18HisTyr: 2.18 ± 1.493
0.0HisXaa: 0.0 ± 0.0
Ile
2.18IleAla: 2.18 ± 1.175
0.0IleCys: 0.0 ± 0.0
1.453IleAsp: 1.453 ± 0.993
4.36IleGlu: 4.36 ± 1.305
0.0IlePhe: 0.0 ± 0.0
3.634IleGly: 3.634 ± 1.284
0.727IleHis: 0.727 ± 0.638
2.18IleIle: 2.18 ± 1.012
2.907IleLys: 2.907 ± 2.375
2.18IleLeu: 2.18 ± 1.227
2.907IleMet: 2.907 ± 1.462
2.907IleAsn: 2.907 ± 1.925
5.087IlePro: 5.087 ± 1.456
4.36IleGln: 4.36 ± 2.453
1.453IleArg: 1.453 ± 0.836
0.727IleSer: 0.727 ± 0.645
0.727IleThr: 0.727 ± 0.645
5.814IleVal: 5.814 ± 0.869
1.453IleTrp: 1.453 ± 0.617
1.453IleTyr: 1.453 ± 1.298
0.0IleXaa: 0.0 ± 0.0
Lys
2.18LysAla: 2.18 ± 1.35
0.727LysCys: 0.727 ± 1.154
3.634LysAsp: 3.634 ± 1.233
4.36LysGlu: 4.36 ± 2.455
2.18LysPhe: 2.18 ± 1.49
2.907LysGly: 2.907 ± 1.672
0.0LysHis: 0.0 ± 0.0
3.634LysIle: 3.634 ± 1.622
1.453LysLys: 1.453 ± 1.31
5.814LysLeu: 5.814 ± 3.665
0.727LysMet: 0.727 ± 1.082
2.907LysAsn: 2.907 ± 2.938
4.36LysPro: 4.36 ± 1.668
2.907LysGln: 2.907 ± 1.469
5.087LysArg: 5.087 ± 4.013
3.634LysSer: 3.634 ± 1.36
1.453LysThr: 1.453 ± 1.317
1.453LysVal: 1.453 ± 0.685
0.727LysTrp: 0.727 ± 0.497
4.36LysTyr: 4.36 ± 1.826
0.0LysXaa: 0.0 ± 0.0
Leu
5.814LeuAla: 5.814 ± 2.062
0.727LeuCys: 0.727 ± 0.497
2.907LeuAsp: 2.907 ± 1.469
5.814LeuGlu: 5.814 ± 1.859
2.907LeuPhe: 2.907 ± 1.764
7.994LeuGly: 7.994 ± 2.65
2.18LeuHis: 2.18 ± 1.16
4.36LeuIle: 4.36 ± 1.437
4.36LeuLys: 4.36 ± 1.001
5.814LeuLeu: 5.814 ± 1.876
2.18LeuMet: 2.18 ± 1.175
2.907LeuAsn: 2.907 ± 1.376
3.634LeuPro: 3.634 ± 1.798
4.36LeuGln: 4.36 ± 1.927
5.814LeuArg: 5.814 ± 1.357
2.907LeuSer: 2.907 ± 1.574
2.907LeuThr: 2.907 ± 1.985
2.18LeuVal: 2.18 ± 0.693
2.18LeuTrp: 2.18 ± 1.012
2.18LeuTyr: 2.18 ± 0.864
0.0LeuXaa: 0.0 ± 0.0
Met
5.814MetAla: 5.814 ± 2.017
0.0MetCys: 0.0 ± 0.0
0.727MetAsp: 0.727 ± 0.497
0.727MetGlu: 0.727 ± 0.497
0.727MetPhe: 0.727 ± 0.497
3.634MetGly: 3.634 ± 1.813
0.0MetHis: 0.0 ± 0.0
2.18MetIle: 2.18 ± 2.152
1.453MetLys: 1.453 ± 1.298
0.727MetLeu: 0.727 ± 0.497
0.727MetMet: 0.727 ± 0.638
1.453MetAsn: 1.453 ± 1.069
1.453MetPro: 1.453 ± 0.993
2.18MetGln: 2.18 ± 0.897
5.814MetArg: 5.814 ± 3.629
1.453MetSer: 1.453 ± 0.993
2.18MetThr: 2.18 ± 0.897
0.727MetVal: 0.727 ± 1.361
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.727AsnAla: 0.727 ± 0.497
0.727AsnCys: 0.727 ± 0.984
2.18AsnAsp: 2.18 ± 1.288
3.634AsnGlu: 3.634 ± 1.233
0.727AsnPhe: 0.727 ± 0.497
0.0AsnGly: 0.0 ± 0.0
0.727AsnHis: 0.727 ± 1.154
2.18AsnIle: 2.18 ± 1.559
1.453AsnLys: 1.453 ± 1.289
5.087AsnLeu: 5.087 ± 1.521
2.18AsnMet: 2.18 ± 1.913
2.907AsnAsn: 2.907 ± 1.233
2.18AsnPro: 2.18 ± 1.934
2.18AsnGln: 2.18 ± 1.227
5.814AsnArg: 5.814 ± 2.073
2.907AsnSer: 2.907 ± 0.979
2.18AsnThr: 2.18 ± 1.227
5.814AsnVal: 5.814 ± 2.553
0.727AsnTrp: 0.727 ± 0.497
4.36AsnTyr: 4.36 ± 1.437
0.0AsnXaa: 0.0 ± 0.0
Pro
3.634ProAla: 3.634 ± 1.681
1.453ProCys: 1.453 ± 1.31
2.18ProAsp: 2.18 ± 0.916
2.907ProGlu: 2.907 ± 1.338
1.453ProPhe: 1.453 ± 0.617
3.634ProGly: 3.634 ± 2.069
0.727ProHis: 0.727 ± 0.645
2.907ProIle: 2.907 ± 1.304
2.18ProLys: 2.18 ± 0.916
4.36ProLeu: 4.36 ± 1.574
0.727ProMet: 0.727 ± 0.497
2.18ProAsn: 2.18 ± 0.916
0.0ProPro: 0.0 ± 0.0
3.634ProGln: 3.634 ± 2.483
3.634ProArg: 3.634 ± 1.798
1.453ProSer: 1.453 ± 1.069
2.18ProThr: 2.18 ± 2.951
7.267ProVal: 7.267 ± 3.004
0.727ProTrp: 0.727 ± 0.497
1.453ProTyr: 1.453 ± 1.618
0.0ProXaa: 0.0 ± 0.0
Gln
4.36GlnAla: 4.36 ± 2.055
0.0GlnCys: 0.0 ± 0.0
2.18GlnAsp: 2.18 ± 1.46
5.814GlnGlu: 5.814 ± 1.552
1.453GlnPhe: 1.453 ± 0.685
5.814GlnGly: 5.814 ± 2.658
0.727GlnHis: 0.727 ± 0.497
1.453GlnIle: 1.453 ± 0.993
2.18GlnLys: 2.18 ± 0.693
2.907GlnLeu: 2.907 ± 1.44
1.453GlnMet: 1.453 ± 1.207
2.907GlnAsn: 2.907 ± 0.868
2.18GlnPro: 2.18 ± 1.073
2.907GlnGln: 2.907 ± 1.37
5.087GlnArg: 5.087 ± 1.105
2.907GlnSer: 2.907 ± 1.469
4.36GlnThr: 4.36 ± 1.385
3.634GlnVal: 3.634 ± 2.413
0.727GlnTrp: 0.727 ± 0.638
0.727GlnTyr: 0.727 ± 0.645
0.0GlnXaa: 0.0 ± 0.0
Arg
5.087ArgAla: 5.087 ± 1.732
2.907ArgCys: 2.907 ± 1.464
7.994ArgAsp: 7.994 ± 2.199
5.087ArgGlu: 5.087 ± 3.119
0.0ArgPhe: 0.0 ± 0.0
2.18ArgGly: 2.18 ± 0.693
0.727ArgHis: 0.727 ± 0.645
1.453ArgIle: 1.453 ± 1.088
2.907ArgLys: 2.907 ± 1.772
7.994ArgLeu: 7.994 ± 2.409
4.36ArgMet: 4.36 ± 3.698
3.634ArgAsn: 3.634 ± 1.882
5.087ArgPro: 5.087 ± 2.238
1.453ArgGln: 1.453 ± 0.685
3.634ArgArg: 3.634 ± 1.91
5.087ArgSer: 5.087 ± 1.983
2.18ArgThr: 2.18 ± 1.35
5.087ArgVal: 5.087 ± 0.976
0.0ArgTrp: 0.0 ± 0.0
4.36ArgTyr: 4.36 ± 1.85
0.0ArgXaa: 0.0 ± 0.0
Ser
3.634SerAla: 3.634 ± 1.217
0.0SerCys: 0.0 ± 0.0
1.453SerAsp: 1.453 ± 0.617
4.36SerGlu: 4.36 ± 2.452
2.907SerPhe: 2.907 ± 1.562
4.36SerGly: 4.36 ± 1.948
0.727SerHis: 0.727 ± 1.361
2.18SerIle: 2.18 ± 0.693
6.541SerLys: 6.541 ± 2.259
3.634SerLeu: 3.634 ± 1.798
0.727SerMet: 0.727 ± 0.882
2.907SerAsn: 2.907 ± 1.364
3.634SerPro: 3.634 ± 1.798
2.907SerGln: 2.907 ± 1.149
3.634SerArg: 3.634 ± 1.146
4.36SerSer: 4.36 ± 2.055
2.907SerThr: 2.907 ± 1.364
4.36SerVal: 4.36 ± 1.468
2.907SerTrp: 2.907 ± 1.462
1.453SerTyr: 1.453 ± 0.685
0.0SerXaa: 0.0 ± 0.0
Thr
3.634ThrAla: 3.634 ± 1.663
0.0ThrCys: 0.0 ± 0.0
3.634ThrAsp: 3.634 ± 1.278
2.18ThrGlu: 2.18 ± 1.1
3.634ThrPhe: 3.634 ± 1.742
2.907ThrGly: 2.907 ± 1.408
0.727ThrHis: 0.727 ± 0.984
1.453ThrIle: 1.453 ± 1.069
1.453ThrLys: 1.453 ± 0.685
0.727ThrLeu: 0.727 ± 0.645
2.18ThrMet: 2.18 ± 1.227
1.453ThrAsn: 1.453 ± 0.836
2.18ThrPro: 2.18 ± 1.173
2.18ThrGln: 2.18 ± 1.227
2.907ThrArg: 2.907 ± 1.364
5.814ThrSer: 5.814 ± 1.207
2.907ThrThr: 2.907 ± 0.979
3.634ThrVal: 3.634 ± 0.698
0.0ThrTrp: 0.0 ± 0.0
1.453ThrTyr: 1.453 ± 1.452
0.0ThrXaa: 0.0 ± 0.0
Val
2.18ValAla: 2.18 ± 1.929
1.453ValCys: 1.453 ± 0.617
3.634ValAsp: 3.634 ± 1.257
7.994ValGlu: 7.994 ± 1.614
3.634ValPhe: 3.634 ± 1.798
2.18ValGly: 2.18 ± 1.16
2.18ValHis: 2.18 ± 1.01
0.727ValIle: 0.727 ± 0.645
7.994ValLys: 7.994 ± 2.504
2.907ValLeu: 2.907 ± 1.11
0.0ValMet: 0.0 ± 0.0
5.087ValAsn: 5.087 ± 1.512
3.634ValPro: 3.634 ± 1.819
5.087ValGln: 5.087 ± 1.904
6.541ValArg: 6.541 ± 1.453
3.634ValSer: 3.634 ± 1.267
3.634ValThr: 3.634 ± 1.298
4.36ValVal: 4.36 ± 1.931
0.727ValTrp: 0.727 ± 0.497
3.634ValTyr: 3.634 ± 2.503
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.727TrpCys: 0.727 ± 0.645
1.453TrpAsp: 1.453 ± 0.617
2.18TrpGlu: 2.18 ± 1.012
0.727TrpPhe: 0.727 ± 0.497
0.727TrpGly: 0.727 ± 0.638
0.727TrpHis: 0.727 ± 0.497
0.727TrpIle: 0.727 ± 0.497
1.453TrpLys: 1.453 ± 1.31
2.18TrpLeu: 2.18 ± 1.49
0.727TrpMet: 0.727 ± 0.984
0.727TrpAsn: 0.727 ± 0.497
1.453TrpPro: 1.453 ± 0.993
0.727TrpGln: 0.727 ± 0.497
0.727TrpArg: 0.727 ± 1.361
0.727TrpSer: 0.727 ± 0.638
1.453TrpThr: 1.453 ± 0.993
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.18TyrAla: 2.18 ± 1.788
0.727TyrCys: 0.727 ± 0.497
5.814TyrAsp: 5.814 ± 3.229
0.727TyrGlu: 0.727 ± 0.645
2.18TyrPhe: 2.18 ± 0.864
5.087TyrGly: 5.087 ± 0.965
0.727TyrHis: 0.727 ± 0.645
2.18TyrIle: 2.18 ± 0.897
1.453TyrLys: 1.453 ± 0.617
1.453TyrLeu: 1.453 ± 1.452
0.727TyrMet: 0.727 ± 0.497
1.453TyrAsn: 1.453 ± 0.993
1.453TyrPro: 1.453 ± 1.052
2.18TyrGln: 2.18 ± 0.693
3.634TyrArg: 3.634 ± 1.163
2.18TyrSer: 2.18 ± 1.929
2.18TyrThr: 2.18 ± 0.916
5.814TyrVal: 5.814 ± 1.532
1.453TyrTrp: 1.453 ± 0.617
4.36TyrTyr: 4.36 ± 1.247
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1377 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski