Amino acid dipepetide frequency for Acetobacter pasteurianus (strain NBRC 3283 / LMG 1513 / CCTM 1153)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.848AlaAla: 13.848 ± 0.177	1.485AlaCys: 1.485 ± 0.042	6.08AlaAsp: 6.08 ± 0.087	6.654AlaGlu: 6.654 ± 0.114	3.839AlaPhe: 3.839 ± 0.068	9.405AlaGly: 9.405 ± 0.118	2.712AlaHis: 2.712 ± 0.058	5.34AlaIle: 5.34 ± 0.089	3.472AlaLys: 3.472 ± 0.074	12.354AlaLeu: 12.354 ± 0.142	3.03AlaMet: 3.03 ± 0.064	2.851AlaAsn: 2.851 ± 0.052	5.604AlaPro: 5.604 ± 0.109	5.032AlaGln: 5.032 ± 0.102	7.596AlaArg: 7.596 ± 0.113	6.375AlaSer: 6.375 ± 0.091	6.113AlaThr: 6.113 ± 0.089	7.516AlaVal: 7.516 ± 0.098	1.55AlaTrp: 1.55 ± 0.043	2.459AlaTyr: 2.459 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	1.343CysAla: 1.343 ± 0.041	0.186CysCys: 0.186 ± 0.015	0.504CysAsp: 0.504 ± 0.023	0.453CysGlu: 0.453 ± 0.023	0.525CysPhe: 0.525 ± 0.026	1.198CysGly: 1.198 ± 0.04	0.31CysHis: 0.31 ± 0.02	0.534CysIle: 0.534 ± 0.029	0.282CysLys: 0.282 ± 0.018	1.123CysLeu: 1.123 ± 0.035	0.284CysMet: 0.284 ± 0.016	0.28CysAsn: 0.28 ± 0.015	0.575CysPro: 0.575 ± 0.031	0.442CysGln: 0.442 ± 0.025	0.728CysArg: 0.728 ± 0.03	0.663CysSer: 0.663 ± 0.028	0.615CysThr: 0.615 ± 0.025	0.924CysVal: 0.924 ± 0.036	0.139CysTrp: 0.139 ± 0.012	0.243CysTyr: 0.243 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	6.0AspAla: 6.0 ± 0.081	0.462AspCys: 0.462 ± 0.021	2.568AspAsp: 2.568 ± 0.057	2.829AspGlu: 2.829 ± 0.056	1.963AspPhe: 1.963 ± 0.051	4.249AspGly: 4.249 ± 0.075	1.248AspHis: 1.248 ± 0.038	3.276AspIle: 3.276 ± 0.058	1.895AspLys: 1.895 ± 0.052	5.282AspLeu: 5.282 ± 0.074	1.624AspMet: 1.624 ± 0.034	1.502AspAsn: 1.502 ± 0.046	2.793AspPro: 2.793 ± 0.058	1.71AspGln: 1.71 ± 0.041	3.261AspArg: 3.261 ± 0.065	2.308AspSer: 2.308 ± 0.056	2.9AspThr: 2.9 ± 0.058	4.124AspVal: 4.124 ± 0.064	0.908AspTrp: 0.908 ± 0.032	1.352AspTyr: 1.352 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.414GluAla: 6.414 ± 0.105	0.492GluCys: 0.492 ± 0.024	2.874GluAsp: 2.874 ± 0.059	3.262GluGlu: 3.262 ± 0.081	1.476GluPhe: 1.476 ± 0.041	4.13GluGly: 4.13 ± 0.072	1.414GluHis: 1.414 ± 0.043	2.789GluIle: 2.789 ± 0.055	2.862GluLys: 2.862 ± 0.066	4.561GluLeu: 4.561 ± 0.073	1.32GluMet: 1.32 ± 0.039	2.101GluAsn: 2.101 ± 0.048	2.132GluPro: 2.132 ± 0.06	2.672GluGln: 2.672 ± 0.057	3.894GluArg: 3.894 ± 0.09	2.388GluSer: 2.388 ± 0.048	3.245GluThr: 3.245 ± 0.064	3.241GluVal: 3.241 ± 0.059	0.766GluTrp: 0.766 ± 0.028	1.093GluTyr: 1.093 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.842PheAla: 3.842 ± 0.057	0.626PheCys: 0.626 ± 0.027	2.017PheAsp: 2.017 ± 0.043	1.703PheGlu: 1.703 ± 0.042	1.424PhePhe: 1.424 ± 0.045	3.3PheGly: 3.3 ± 0.06	0.862PheHis: 0.862 ± 0.031	1.702PheIle: 1.702 ± 0.046	0.865PheLys: 0.865 ± 0.03	3.721PheLeu: 3.721 ± 0.075	1.027PheMet: 1.027 ± 0.032	1.163PheAsn: 1.163 ± 0.04	1.759PhePro: 1.759 ± 0.046	1.026PheGln: 1.026 ± 0.032	2.287PheArg: 2.287 ± 0.052	2.718PheSer: 2.718 ± 0.061	2.091PheThr: 2.091 ± 0.047	2.742PheVal: 2.742 ± 0.063	0.561PheTrp: 0.561 ± 0.029	0.964PheTyr: 0.964 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	7.667GlyAla: 7.667 ± 0.103	1.03GlyCys: 1.03 ± 0.036	3.558GlyAsp: 3.558 ± 0.064	3.643GlyGlu: 3.643 ± 0.067	3.31GlyPhe: 3.31 ± 0.052	6.842GlyGly: 6.842 ± 0.144	2.07GlyHis: 2.07 ± 0.047	4.398GlyIle: 4.398 ± 0.072	3.546GlyLys: 3.546 ± 0.076	8.36GlyLeu: 8.36 ± 0.105	2.496GlyMet: 2.496 ± 0.049	2.516GlyAsn: 2.516 ± 0.06	3.169GlyPro: 3.169 ± 0.064	3.316GlyGln: 3.316 ± 0.069	5.217GlyArg: 5.217 ± 0.096	4.643GlySer: 4.643 ± 0.083	4.769GlyThr: 4.769 ± 0.075	5.911GlyVal: 5.911 ± 0.09	1.458GlyTrp: 1.458 ± 0.038	2.271GlyTyr: 2.271 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	2.81HisAla: 2.81 ± 0.066	0.269HisCys: 0.269 ± 0.016	1.42HisAsp: 1.42 ± 0.041	1.26HisGlu: 1.26 ± 0.037	0.921HisPhe: 0.921 ± 0.029	2.091HisGly: 2.091 ± 0.049	0.757HisHis: 0.757 ± 0.034	1.278HisIle: 1.278 ± 0.039	0.879HisLys: 0.879 ± 0.034	2.39HisLeu: 2.39 ± 0.054	0.586HisMet: 0.586 ± 0.026	0.816HisAsn: 0.816 ± 0.029	1.515HisPro: 1.515 ± 0.045	0.842HisGln: 0.842 ± 0.032	1.343HisArg: 1.343 ± 0.041	1.232HisSer: 1.232 ± 0.04	1.412HisThr: 1.412 ± 0.044	1.809HisVal: 1.809 ± 0.045	0.373HisTrp: 0.373 ± 0.02	0.635HisTyr: 0.635 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.886IleAla: 5.886 ± 0.088	0.672IleCys: 0.672 ± 0.027	2.666IleAsp: 2.666 ± 0.058	2.721IleGlu: 2.721 ± 0.068	1.807IlePhe: 1.807 ± 0.049	4.335IleGly: 4.335 ± 0.077	1.011IleHis: 1.011 ± 0.036	2.373IleIle: 2.373 ± 0.058	1.595IleLys: 1.595 ± 0.047	4.831IleLeu: 4.831 ± 0.084	1.309IleMet: 1.309 ± 0.039	1.621IleAsn: 1.621 ± 0.049	2.648IlePro: 2.648 ± 0.053	1.595IleGln: 1.595 ± 0.045	3.257IleArg: 3.257 ± 0.057	3.368IleSer: 3.368 ± 0.067	3.414IleThr: 3.414 ± 0.075	3.749IleVal: 3.749 ± 0.066	0.713IleTrp: 0.713 ± 0.028	1.146IleTyr: 1.146 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	4.229LysAla: 4.229 ± 0.076	0.207LysCys: 0.207 ± 0.016	1.949LysAsp: 1.949 ± 0.05	2.1LysGlu: 2.1 ± 0.052	0.898LysPhe: 0.898 ± 0.034	2.828LysGly: 2.828 ± 0.058	0.811LysHis: 0.811 ± 0.037	1.869LysIle: 1.869 ± 0.051	1.825LysLys: 1.825 ± 0.053	3.506LysLeu: 3.506 ± 0.075	0.901LysMet: 0.901 ± 0.033	1.444LysAsn: 1.444 ± 0.043	2.223LysPro: 2.223 ± 0.056	1.508LysGln: 1.508 ± 0.045	2.299LysArg: 2.299 ± 0.056	1.938LysSer: 1.938 ± 0.05	2.288LysThr: 2.288 ± 0.057	2.364LysVal: 2.364 ± 0.064	0.476LysTrp: 0.476 ± 0.02	0.711LysTyr: 0.711 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	12.402LeuAla: 12.402 ± 0.139	1.307LeuCys: 1.307 ± 0.036	5.535LeuAsp: 5.535 ± 0.076	5.263LeuGlu: 5.263 ± 0.094	3.835LeuPhe: 3.835 ± 0.074	7.318LeuGly: 7.318 ± 0.098	2.569LeuHis: 2.569 ± 0.052	4.436LeuIle: 4.436 ± 0.082	3.795LeuLys: 3.795 ± 0.073	10.087LeuLeu: 10.087 ± 0.166	2.405LeuMet: 2.405 ± 0.046	2.982LeuAsn: 2.982 ± 0.065	6.601LeuPro: 6.601 ± 0.106	3.514LeuGln: 3.514 ± 0.063	6.856LeuArg: 6.856 ± 0.093	6.851LeuSer: 6.851 ± 0.089	5.591LeuThr: 5.591 ± 0.076	6.851LeuVal: 6.851 ± 0.107	1.284LeuTrp: 1.284 ± 0.043	2.302LeuTyr: 2.302 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	3.174MetAla: 3.174 ± 0.054	0.208MetCys: 0.208 ± 0.014	1.324MetAsp: 1.324 ± 0.036	1.249MetGlu: 1.249 ± 0.037	0.74MetPhe: 0.74 ± 0.031	2.036MetGly: 2.036 ± 0.049	0.518MetHis: 0.518 ± 0.024	1.26MetIle: 1.26 ± 0.037	0.977MetLys: 0.977 ± 0.035	2.841MetLeu: 2.841 ± 0.064	0.683MetMet: 0.683 ± 0.028	0.809MetAsn: 0.809 ± 0.032	1.692MetPro: 1.692 ± 0.045	1.226MetGln: 1.226 ± 0.032	1.714MetArg: 1.714 ± 0.045	1.641MetSer: 1.641 ± 0.039	1.754MetThr: 1.754 ± 0.04	1.777MetVal: 1.777 ± 0.044	0.232MetTrp: 0.232 ± 0.016	0.353MetTyr: 0.353 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.385AsnAla: 3.385 ± 0.063	0.346AsnCys: 0.346 ± 0.02	1.356AsnAsp: 1.356 ± 0.035	1.197AsnGlu: 1.197 ± 0.033	1.087AsnPhe: 1.087 ± 0.034	2.95AsnGly: 2.95 ± 0.075	0.701AsnHis: 0.701 ± 0.029	1.804AsnIle: 1.804 ± 0.044	1.021AsnLys: 1.021 ± 0.035	2.815AsnLeu: 2.815 ± 0.055	0.867AsnMet: 0.867 ± 0.029	1.025AsnAsn: 1.025 ± 0.042	2.072AsnPro: 2.072 ± 0.045	1.029AsnGln: 1.029 ± 0.036	1.988AsnArg: 1.988 ± 0.051	1.561AsnSer: 1.561 ± 0.044	1.992AsnThr: 1.992 ± 0.046	2.202AsnVal: 2.202 ± 0.058	0.487AsnTrp: 0.487 ± 0.026	0.741AsnTyr: 0.741 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	6.378ProAla: 6.378 ± 0.102	0.485ProCys: 0.485 ± 0.022	3.773ProAsp: 3.773 ± 0.065	4.02ProGlu: 4.02 ± 0.069	2.092ProPhe: 2.092 ± 0.049	3.904ProGly: 3.904 ± 0.069	1.379ProHis: 1.379 ± 0.042	2.102ProIle: 2.102 ± 0.052	1.699ProLys: 1.699 ± 0.049	4.959ProLeu: 4.959 ± 0.08	1.216ProMet: 1.216 ± 0.041	1.49ProAsn: 1.49 ± 0.049	2.893ProPro: 2.893 ± 0.081	2.297ProGln: 2.297 ± 0.045	2.615ProArg: 2.615 ± 0.057	3.182ProSer: 3.182 ± 0.069	2.837ProThr: 2.837 ± 0.063	4.483ProVal: 4.483 ± 0.07	0.767ProTrp: 0.767 ± 0.031	1.314ProTyr: 1.314 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	5.166GlnAla: 5.166 ± 0.091	0.299GlnCys: 0.299 ± 0.017	2.155GlnAsp: 2.155 ± 0.055	2.195GlnGlu: 2.195 ± 0.053	1.256GlnPhe: 1.256 ± 0.035	2.546GlnGly: 2.546 ± 0.049	1.09GlnHis: 1.09 ± 0.036	2.367GlnIle: 2.367 ± 0.051	1.958GlnLys: 1.958 ± 0.05	3.047GlnLeu: 3.047 ± 0.064	0.993GlnMet: 0.993 ± 0.031	1.471GlnAsn: 1.471 ± 0.036	2.33GlnPro: 2.33 ± 0.059	1.957GlnGln: 1.957 ± 0.063	2.427GlnArg: 2.427 ± 0.045	2.001GlnSer: 2.001 ± 0.057	2.437GlnThr: 2.437 ± 0.055	2.468GlnVal: 2.468 ± 0.06	0.513GlnTrp: 0.513 ± 0.023	0.823GlnTyr: 0.823 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	6.368ArgAla: 6.368 ± 0.097	0.566ArgCys: 0.566 ± 0.023	3.13ArgAsp: 3.13 ± 0.068	3.416ArgGlu: 3.416 ± 0.076	2.646ArgPhe: 2.646 ± 0.058	4.025ArgGly: 4.025 ± 0.068	1.838ArgHis: 1.838 ± 0.045	3.952ArgIle: 3.952 ± 0.069	2.716ArgLys: 2.716 ± 0.057	7.243ArgLeu: 7.243 ± 0.11	1.856ArgMet: 1.856 ± 0.043	2.112ArgAsn: 2.112 ± 0.053	3.144ArgPro: 3.144 ± 0.068	2.948ArgGln: 2.948 ± 0.057	4.768ArgArg: 4.768 ± 0.1	3.254ArgSer: 3.254 ± 0.059	3.394ArgThr: 3.394 ± 0.059	4.303ArgVal: 4.303 ± 0.082	0.994ArgTrp: 0.994 ± 0.032	1.861ArgTyr: 1.861 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	6.635SerAla: 6.635 ± 0.104	0.671SerCys: 0.671 ± 0.026	2.848SerAsp: 2.848 ± 0.059	2.428SerGlu: 2.428 ± 0.055	2.502SerPhe: 2.502 ± 0.058	5.656SerGly: 5.656 ± 0.114	1.351SerHis: 1.351 ± 0.037	3.037SerIle: 3.037 ± 0.057	1.652SerLys: 1.652 ± 0.047	5.913SerLeu: 5.913 ± 0.076	1.584SerMet: 1.584 ± 0.04	1.563SerAsn: 1.563 ± 0.044	2.984SerPro: 2.984 ± 0.069	1.792SerGln: 1.792 ± 0.044	3.604SerArg: 3.604 ± 0.063	3.867SerSer: 3.867 ± 0.076	3.053SerThr: 3.053 ± 0.066	4.448SerVal: 4.448 ± 0.079	0.893SerTrp: 0.893 ± 0.029	1.51SerTyr: 1.51 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	6.103ThrAla: 6.103 ± 0.103	0.621ThrCys: 0.621 ± 0.025	2.941ThrAsp: 2.941 ± 0.056	2.903ThrGlu: 2.903 ± 0.057	1.964ThrPhe: 1.964 ± 0.05	5.103ThrGly: 5.103 ± 0.082	1.429ThrHis: 1.429 ± 0.043	2.829ThrIle: 2.829 ± 0.06	1.581ThrLys: 1.581 ± 0.047	6.736ThrLeu: 6.736 ± 0.088	1.131ThrMet: 1.131 ± 0.035	1.537ThrAsn: 1.537 ± 0.047	3.989ThrPro: 3.989 ± 0.077	2.236ThrGln: 2.236 ± 0.053	3.363ThrArg: 3.363 ± 0.059	3.263ThrSer: 3.263 ± 0.066	3.279ThrThr: 3.279 ± 0.065	4.299ThrVal: 4.299 ± 0.066	0.839ThrTrp: 0.839 ± 0.031	1.352ThrTyr: 1.352 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	7.93ValAla: 7.93 ± 0.096	0.847ValCys: 0.847 ± 0.03	3.505ValAsp: 3.505 ± 0.072	3.965ValGlu: 3.965 ± 0.076	2.657ValPhe: 2.657 ± 0.052	5.064ValGly: 5.064 ± 0.092	1.483ValHis: 1.483 ± 0.042	3.654ValIle: 3.654 ± 0.066	2.328ValLys: 2.328 ± 0.056	7.914ValLeu: 7.914 ± 0.12	2.004ValMet: 2.004 ± 0.045	1.947ValAsn: 1.947 ± 0.049	3.904ValPro: 3.904 ± 0.068	2.716ValGln: 2.716 ± 0.056	4.557ValArg: 4.557 ± 0.071	4.644ValSer: 4.644 ± 0.071	4.222ValThr: 4.222 ± 0.079	5.526ValVal: 5.526 ± 0.094	1.042ValTrp: 1.042 ± 0.038	1.468ValTyr: 1.468 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.23TrpAla: 1.23 ± 0.04	0.254TrpCys: 0.254 ± 0.016	0.641TrpAsp: 0.641 ± 0.027	0.644TrpGlu: 0.644 ± 0.028	0.574TrpPhe: 0.574 ± 0.024	1.008TrpGly: 1.008 ± 0.039	0.478TrpHis: 0.478 ± 0.021	0.657TrpIle: 0.657 ± 0.024	0.661TrpLys: 0.661 ± 0.025	1.743TrpLeu: 1.743 ± 0.045	0.38TrpMet: 0.38 ± 0.022	0.551TrpAsn: 0.551 ± 0.028	0.723TrpPro: 0.723 ± 0.031	0.782TrpGln: 0.782 ± 0.025	1.146TrpArg: 1.146 ± 0.035	0.851TrpSer: 0.851 ± 0.031	0.734TrpThr: 0.734 ± 0.027	0.939TrpVal: 0.939 ± 0.032	0.222TrpTrp: 0.222 ± 0.015	0.334TrpTyr: 0.334 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.504TyrAla: 2.504 ± 0.057	0.316TyrCys: 0.316 ± 0.018	1.415TyrAsp: 1.415 ± 0.043	1.222TyrGlu: 1.222 ± 0.042	0.885TyrPhe: 0.885 ± 0.036	2.201TyrGly: 2.201 ± 0.057	0.607TyrHis: 0.607 ± 0.025	1.061TyrIle: 1.061 ± 0.037	0.767TyrLys: 0.767 ± 0.033	2.357TyrLeu: 2.357 ± 0.053	0.511TyrMet: 0.511 ± 0.024	0.841TyrAsn: 0.841 ± 0.033	1.136TyrPro: 1.136 ± 0.035	0.858TyrGln: 0.858 ± 0.032	1.614TyrArg: 1.614 ± 0.041	1.243TyrSer: 1.243 ± 0.046	1.361TyrThr: 1.361 ± 0.048	1.701TyrVal: 1.701 ± 0.049	0.335TyrTrp: 0.335 ± 0.019	0.74TyrTyr: 0.74 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2906 proteins (941337 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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