Amino acid dipepetide frequency for Kiritimatiellaeota bacterium S-5007

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.708AlaAla: 9.708 ± 0.115	1.147AlaCys: 1.147 ± 0.035	5.791AlaAsp: 5.791 ± 0.082	6.257AlaGlu: 6.257 ± 0.087	3.429AlaPhe: 3.429 ± 0.063	8.105AlaGly: 8.105 ± 0.094	1.567AlaHis: 1.567 ± 0.038	4.265AlaIle: 4.265 ± 0.068	3.543AlaLys: 3.543 ± 0.068	8.577AlaLeu: 8.577 ± 0.101	2.203AlaMet: 2.203 ± 0.051	2.614AlaAsn: 2.614 ± 0.053	3.565AlaPro: 3.565 ± 0.068	2.956AlaGln: 2.956 ± 0.049	4.39AlaArg: 4.39 ± 0.077	4.842AlaSer: 4.842 ± 0.079	3.891AlaThr: 3.891 ± 0.071	7.399AlaVal: 7.399 ± 0.089	1.218AlaTrp: 1.218 ± 0.035	2.487AlaTyr: 2.487 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	1.119CysAla: 1.119 ± 0.032	0.245CysCys: 0.245 ± 0.012	0.755CysAsp: 0.755 ± 0.026	0.757CysGlu: 0.757 ± 0.027	0.596CysPhe: 0.596 ± 0.023	1.366CysGly: 1.366 ± 0.04	0.291CysHis: 0.291 ± 0.017	0.726CysIle: 0.726 ± 0.025	0.484CysLys: 0.484 ± 0.018	1.108CysLeu: 1.108 ± 0.029	0.303CysMet: 0.303 ± 0.016	0.412CysAsn: 0.412 ± 0.019	0.727CysPro: 0.727 ± 0.026	0.303CysGln: 0.303 ± 0.018	0.843CysArg: 0.843 ± 0.03	0.997CysSer: 0.997 ± 0.03	0.685CysThr: 0.685 ± 0.029	0.833CysVal: 0.833 ± 0.026	0.186CysTrp: 0.186 ± 0.012	0.429CysTyr: 0.429 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	5.382AspAla: 5.382 ± 0.078	0.77AspCys: 0.77 ± 0.026	3.392AspAsp: 3.392 ± 0.062	4.048AspGlu: 4.048 ± 0.067	2.718AspPhe: 2.718 ± 0.055	5.786AspGly: 5.786 ± 0.118	1.287AspHis: 1.287 ± 0.03	3.334AspIle: 3.334 ± 0.051	2.0AspLys: 2.0 ± 0.04	5.817AspLeu: 5.817 ± 0.079	1.282AspMet: 1.282 ± 0.034	2.02AspAsn: 2.02 ± 0.051	3.212AspPro: 3.212 ± 0.072	1.944AspGln: 1.944 ± 0.043	3.451AspArg: 3.451 ± 0.059	3.523AspSer: 3.523 ± 0.071	2.716AspThr: 2.716 ± 0.053	4.144AspVal: 4.144 ± 0.071	1.209AspTrp: 1.209 ± 0.038	2.05AspTyr: 2.05 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	5.435GluAla: 5.435 ± 0.085	0.628GluCys: 0.628 ± 0.025	3.289GluAsp: 3.289 ± 0.054	4.46GluGlu: 4.46 ± 0.083	2.552GluPhe: 2.552 ± 0.056	4.098GluGly: 4.098 ± 0.068	1.39GluHis: 1.39 ± 0.04	3.956GluIle: 3.956 ± 0.068	4.444GluLys: 4.444 ± 0.088	6.643GluLeu: 6.643 ± 0.095	1.94GluMet: 1.94 ± 0.042	2.957GluAsn: 2.957 ± 0.049	2.505GluPro: 2.505 ± 0.046	2.832GluGln: 2.832 ± 0.057	3.509GluArg: 3.509 ± 0.066	3.445GluSer: 3.445 ± 0.061	4.024GluThr: 4.024 ± 0.058	3.938GluVal: 3.938 ± 0.063	1.082GluTrp: 1.082 ± 0.034	1.965GluTyr: 1.965 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	3.417PheAla: 3.417 ± 0.063	0.67PheCys: 0.67 ± 0.023	2.992PheAsp: 2.992 ± 0.065	2.932PheGlu: 2.932 ± 0.057	2.119PhePhe: 2.119 ± 0.046	3.514PheGly: 3.514 ± 0.063	0.848PheHis: 0.848 ± 0.028	2.236PheIle: 2.236 ± 0.047	1.774PheLys: 1.774 ± 0.042	3.548PheLeu: 3.548 ± 0.067	1.022PheMet: 1.022 ± 0.035	1.697PheAsn: 1.697 ± 0.041	1.862PhePro: 1.862 ± 0.042	1.563PheGln: 1.563 ± 0.037	2.295PheArg: 2.295 ± 0.044	3.369PheSer: 3.369 ± 0.055	2.262PheThr: 2.262 ± 0.049	2.83PheVal: 2.83 ± 0.054	0.674PheTrp: 0.674 ± 0.026	1.494PheTyr: 1.494 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	6.377GlyAla: 6.377 ± 0.096	1.181GlyCys: 1.181 ± 0.035	4.52GlyAsp: 4.52 ± 0.081	4.49GlyGlu: 4.49 ± 0.063	3.771GlyPhe: 3.771 ± 0.063	6.498GlyGly: 6.498 ± 0.105	1.526GlyHis: 1.526 ± 0.037	4.949GlyIle: 4.949 ± 0.077	4.061GlyLys: 4.061 ± 0.071	7.261GlyLeu: 7.261 ± 0.101	2.241GlyMet: 2.241 ± 0.042	2.845GlyAsn: 2.845 ± 0.058	2.534GlyPro: 2.534 ± 0.058	2.512GlyGln: 2.512 ± 0.048	4.371GlyArg: 4.371 ± 0.063	5.106GlySer: 5.106 ± 0.096	5.193GlyThr: 5.193 ± 0.098	5.597GlyVal: 5.597 ± 0.089	1.472GlyTrp: 1.472 ± 0.043	2.702GlyTyr: 2.702 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	1.631HisAla: 1.631 ± 0.04	0.345HisCys: 0.345 ± 0.018	1.102HisAsp: 1.102 ± 0.034	1.113HisGlu: 1.113 ± 0.032	0.953HisPhe: 0.953 ± 0.028	1.579HisGly: 1.579 ± 0.039	0.571HisHis: 0.571 ± 0.028	1.159HisIle: 1.159 ± 0.031	0.711HisLys: 0.711 ± 0.026	1.977HisLeu: 1.977 ± 0.045	0.436HisMet: 0.436 ± 0.02	0.683HisAsn: 0.683 ± 0.024	1.358HisPro: 1.358 ± 0.038	0.661HisGln: 0.661 ± 0.022	1.215HisArg: 1.215 ± 0.038	1.212HisSer: 1.212 ± 0.033	1.016HisThr: 1.016 ± 0.029	1.266HisVal: 1.266 ± 0.035	0.404HisTrp: 0.404 ± 0.022	0.743HisTyr: 0.743 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	4.969IleAla: 4.969 ± 0.073	0.892IleCys: 0.892 ± 0.029	3.815IleAsp: 3.815 ± 0.055	3.897IleGlu: 3.897 ± 0.07	2.193IlePhe: 2.193 ± 0.049	4.703IleGly: 4.703 ± 0.079	1.22IleHis: 1.22 ± 0.03	3.074IleIle: 3.074 ± 0.054	2.295IleLys: 2.295 ± 0.044	5.135IleLeu: 5.135 ± 0.075	1.107IleMet: 1.107 ± 0.035	2.122IleAsn: 2.122 ± 0.048	2.934IlePro: 2.934 ± 0.053	2.049IleGln: 2.049 ± 0.045	3.448IleArg: 3.448 ± 0.058	3.797IleSer: 3.797 ± 0.063	3.229IleThr: 3.229 ± 0.06	3.525IleVal: 3.525 ± 0.065	0.732IleTrp: 0.732 ± 0.026	1.7IleTyr: 1.7 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	4.07LysAla: 4.07 ± 0.075	0.426LysCys: 0.426 ± 0.021	2.517LysAsp: 2.517 ± 0.057	3.43LysGlu: 3.43 ± 0.062	1.398LysPhe: 1.398 ± 0.035	2.991LysGly: 2.991 ± 0.053	0.951LysHis: 0.951 ± 0.027	2.886LysIle: 2.886 ± 0.056	3.463LysLys: 3.463 ± 0.078	4.184LysLeu: 4.184 ± 0.067	1.313LysMet: 1.313 ± 0.035	2.175LysAsn: 2.175 ± 0.048	2.239LysPro: 2.239 ± 0.053	1.877LysGln: 1.877 ± 0.045	2.446LysArg: 2.446 ± 0.044	2.41LysSer: 2.41 ± 0.05	3.272LysThr: 3.272 ± 0.059	2.879LysVal: 2.879 ± 0.053	0.688LysTrp: 0.688 ± 0.028	1.401LysTyr: 1.401 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	8.279LeuAla: 8.279 ± 0.1	1.382LeuCys: 1.382 ± 0.037	5.545LeuAsp: 5.545 ± 0.079	6.012LeuGlu: 6.012 ± 0.085	4.291LeuPhe: 4.291 ± 0.066	6.431LeuGly: 6.431 ± 0.087	1.74LeuHis: 1.74 ± 0.042	5.535LeuIle: 5.535 ± 0.083	4.905LeuLys: 4.905 ± 0.072	8.858LeuLeu: 8.858 ± 0.112	2.381LeuMet: 2.381 ± 0.045	3.639LeuAsn: 3.639 ± 0.054	4.796LeuPro: 4.796 ± 0.065	3.26LeuGln: 3.26 ± 0.06	5.235LeuArg: 5.235 ± 0.081	6.645LeuSer: 6.645 ± 0.093	5.423LeuThr: 5.423 ± 0.075	5.741LeuVal: 5.741 ± 0.083	1.141LeuTrp: 1.141 ± 0.035	2.782LeuTyr: 2.782 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.203MetAla: 2.203 ± 0.048	0.228MetCys: 0.228 ± 0.015	1.489MetAsp: 1.489 ± 0.037	1.487MetGlu: 1.487 ± 0.034	0.779MetPhe: 0.779 ± 0.032	1.718MetGly: 1.718 ± 0.041	0.471MetHis: 0.471 ± 0.018	1.541MetIle: 1.541 ± 0.038	1.867MetLys: 1.867 ± 0.042	2.456MetLeu: 2.456 ± 0.048	0.764MetMet: 0.764 ± 0.031	1.215MetAsn: 1.215 ± 0.031	1.271MetPro: 1.271 ± 0.03	0.918MetGln: 0.918 ± 0.03	1.321MetArg: 1.321 ± 0.037	1.467MetSer: 1.467 ± 0.036	1.487MetThr: 1.487 ± 0.039	1.623MetVal: 1.623 ± 0.04	0.246MetTrp: 0.246 ± 0.013	0.477MetTyr: 0.477 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.284AsnAla: 3.284 ± 0.057	0.525AsnCys: 0.525 ± 0.022	2.174AsnAsp: 2.174 ± 0.051	2.133AsnGlu: 2.133 ± 0.041	1.348AsnPhe: 1.348 ± 0.033	3.617AsnGly: 3.617 ± 0.082	0.765AsnHis: 0.765 ± 0.026	2.453AsnIle: 2.453 ± 0.049	1.314AsnLys: 1.314 ± 0.036	3.655AsnLeu: 3.655 ± 0.056	0.892AsnMet: 0.892 ± 0.026	1.473AsnAsn: 1.473 ± 0.043	2.45AsnPro: 2.45 ± 0.049	1.248AsnGln: 1.248 ± 0.035	2.234AsnArg: 2.234 ± 0.045	2.239AsnSer: 2.239 ± 0.058	2.156AsnThr: 2.156 ± 0.05	2.54AsnVal: 2.54 ± 0.046	0.717AsnTrp: 0.717 ± 0.025	1.201AsnTyr: 1.201 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	4.337ProAla: 4.337 ± 0.065	0.486ProCys: 0.486 ± 0.023	3.572ProAsp: 3.572 ± 0.063	4.298ProGlu: 4.298 ± 0.067	2.106ProPhe: 2.106 ± 0.052	3.721ProGly: 3.721 ± 0.065	1.027ProHis: 1.027 ± 0.032	1.999ProIle: 1.999 ± 0.042	1.887ProLys: 1.887 ± 0.048	3.998ProLeu: 3.998 ± 0.067	1.083ProMet: 1.083 ± 0.031	1.777ProAsn: 1.777 ± 0.046	1.909ProPro: 1.909 ± 0.054	1.599ProGln: 1.599 ± 0.04	1.865ProArg: 1.865 ± 0.041	2.575ProSer: 2.575 ± 0.045	2.124ProThr: 2.124 ± 0.041	4.106ProVal: 4.106 ± 0.068	0.737ProTrp: 0.737 ± 0.027	1.414ProTyr: 1.414 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.14GlnAla: 3.14 ± 0.047	0.432GlnCys: 0.432 ± 0.021	1.553GlnAsp: 1.553 ± 0.037	1.946GlnGlu: 1.946 ± 0.044	1.421GlnPhe: 1.421 ± 0.036	2.178GlnGly: 2.178 ± 0.042	0.705GlnHis: 0.705 ± 0.025	2.201GlnIle: 2.201 ± 0.049	2.087GlnLys: 2.087 ± 0.047	3.298GlnLeu: 3.298 ± 0.06	1.091GlnMet: 1.091 ± 0.03	1.42GlnAsn: 1.42 ± 0.039	1.516GlnPro: 1.516 ± 0.032	1.477GlnGln: 1.477 ± 0.044	1.863GlnArg: 1.863 ± 0.047	2.127GlnSer: 2.127 ± 0.039	2.243GlnThr: 2.243 ± 0.048	2.409GlnVal: 2.409 ± 0.044	0.619GlnTrp: 0.619 ± 0.026	0.997GlnTyr: 0.997 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	4.105ArgAla: 4.105 ± 0.066	0.677ArgCys: 0.677 ± 0.025	2.952ArgAsp: 2.952 ± 0.057	3.563ArgGlu: 3.563 ± 0.067	2.737ArgPhe: 2.737 ± 0.053	3.387ArgGly: 3.387 ± 0.052	1.158ArgHis: 1.158 ± 0.04	3.718ArgIle: 3.718 ± 0.062	2.95ArgLys: 2.95 ± 0.059	5.3ArgLeu: 5.3 ± 0.083	1.604ArgMet: 1.604 ± 0.037	2.139ArgAsn: 2.139 ± 0.047	2.347ArgPro: 2.347 ± 0.053	2.031ArgGln: 2.031 ± 0.049	3.52ArgArg: 3.52 ± 0.072	3.123ArgSer: 3.123 ± 0.049	2.977ArgThr: 2.977 ± 0.052	3.613ArgVal: 3.613 ± 0.059	0.873ArgTrp: 0.873 ± 0.03	1.867ArgTyr: 1.867 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	5.689SerAla: 5.689 ± 0.077	0.786SerCys: 0.786 ± 0.027	3.878SerAsp: 3.878 ± 0.072	3.792SerGlu: 3.792 ± 0.068	2.803SerPhe: 2.803 ± 0.057	6.226SerGly: 6.226 ± 0.101	1.096SerHis: 1.096 ± 0.032	3.439SerIle: 3.439 ± 0.058	2.386SerLys: 2.386 ± 0.047	5.566SerLeu: 5.566 ± 0.081	1.531SerMet: 1.531 ± 0.036	2.281SerAsn: 2.281 ± 0.058	2.789SerPro: 2.789 ± 0.045	1.742SerGln: 1.742 ± 0.04	3.356SerArg: 3.356 ± 0.062	4.294SerSer: 4.294 ± 0.085	3.017SerThr: 3.017 ± 0.054	4.737SerVal: 4.737 ± 0.073	0.976SerTrp: 0.976 ± 0.035	1.881SerTyr: 1.881 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	5.319ThrAla: 5.319 ± 0.082	0.603ThrCys: 0.603 ± 0.024	3.577ThrAsp: 3.577 ± 0.072	3.148ThrGlu: 3.148 ± 0.056	2.36ThrPhe: 2.36 ± 0.05	5.157ThrGly: 5.157 ± 0.073	1.052ThrHis: 1.052 ± 0.031	3.032ThrIle: 3.032 ± 0.055	1.756ThrLys: 1.756 ± 0.041	5.622ThrLeu: 5.622 ± 0.09	1.106ThrMet: 1.106 ± 0.027	2.33ThrAsn: 2.33 ± 0.07	2.945ThrPro: 2.945 ± 0.057	1.563ThrGln: 1.563 ± 0.039	2.443ThrArg: 2.443 ± 0.051	2.902ThrSer: 2.902 ± 0.059	2.703ThrThr: 2.703 ± 0.068	5.131ThrVal: 5.131 ± 0.079	0.763ThrTrp: 0.763 ± 0.027	1.557ThrTyr: 1.557 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	5.764ValAla: 5.764 ± 0.078	1.109ValCys: 1.109 ± 0.03	4.241ValAsp: 4.241 ± 0.073	4.558ValGlu: 4.558 ± 0.072	3.348ValPhe: 3.348 ± 0.065	4.647ValGly: 4.647 ± 0.075	1.412ValHis: 1.412 ± 0.033	3.906ValIle: 3.906 ± 0.068	2.891ValLys: 2.891 ± 0.06	6.892ValLeu: 6.892 ± 0.085	1.644ValMet: 1.644 ± 0.035	2.506ValAsn: 2.506 ± 0.045	3.531ValPro: 3.531 ± 0.056	2.525ValGln: 2.525 ± 0.05	4.013ValArg: 4.013 ± 0.059	5.133ValSer: 5.133 ± 0.081	3.877ValThr: 3.877 ± 0.07	5.02ValVal: 5.02 ± 0.076	1.058ValTrp: 1.058 ± 0.034	2.089ValTyr: 2.089 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	1.136TrpAla: 1.136 ± 0.036	0.184TrpCys: 0.184 ± 0.013	0.935TrpAsp: 0.935 ± 0.033	0.841TrpGlu: 0.841 ± 0.032	0.687TrpPhe: 0.687 ± 0.026	1.025TrpGly: 1.025 ± 0.033	0.415TrpHis: 0.415 ± 0.021	0.918TrpIle: 0.918 ± 0.027	1.0TrpLys: 1.0 ± 0.031	1.381TrpLeu: 1.381 ± 0.032	0.475TrpMet: 0.475 ± 0.019	0.883TrpAsn: 0.883 ± 0.03	0.652TrpPro: 0.652 ± 0.031	0.592TrpGln: 0.592 ± 0.022	0.821TrpArg: 0.821 ± 0.029	0.971TrpSer: 0.971 ± 0.033	0.964TrpThr: 0.964 ± 0.039	0.993TrpVal: 0.993 ± 0.032	0.265TrpTrp: 0.265 ± 0.016	0.46TrpTyr: 0.46 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.593TyrAla: 2.593 ± 0.047	0.45TyrCys: 0.45 ± 0.02	1.997TyrAsp: 1.997 ± 0.047	1.931TyrGlu: 1.931 ± 0.038	1.507TyrPhe: 1.507 ± 0.04	2.457TyrGly: 2.457 ± 0.053	0.643TyrHis: 0.643 ± 0.021	1.509TyrIle: 1.509 ± 0.039	1.196TyrLys: 1.196 ± 0.03	2.744TyrLeu: 2.744 ± 0.051	0.611TyrMet: 0.611 ± 0.023	1.229TyrAsn: 1.229 ± 0.033	1.476TyrPro: 1.476 ± 0.039	1.075TyrGln: 1.075 ± 0.032	2.0TyrArg: 2.0 ± 0.043	2.087TyrSer: 2.087 ± 0.038	1.808TyrThr: 1.808 ± 0.047	1.842TyrVal: 1.842 ± 0.043	0.539TyrTrp: 0.539 ± 0.024	1.146TyrTyr: 1.146 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3062 proteins (1160248 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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