Amino acid dipepetide frequency for Victivallis vadensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.491AlaAla: 14.491 ± 0.144	1.176AlaCys: 1.176 ± 0.027	5.849AlaAsp: 5.849 ± 0.072	7.999AlaGlu: 7.999 ± 0.086	3.721AlaPhe: 3.721 ± 0.05	10.02AlaGly: 10.02 ± 0.098	1.356AlaHis: 1.356 ± 0.034	4.58AlaIle: 4.58 ± 0.061	3.698AlaLys: 3.698 ± 0.062	9.659AlaLeu: 9.659 ± 0.097	2.337AlaMet: 2.337 ± 0.042	2.735AlaAsn: 2.735 ± 0.047	4.792AlaPro: 4.792 ± 0.077	2.437AlaGln: 2.437 ± 0.041	6.104AlaArg: 6.104 ± 0.069	4.509AlaSer: 4.509 ± 0.061	3.631AlaThr: 3.631 ± 0.059	7.961AlaVal: 7.961 ± 0.087	1.337AlaTrp: 1.337 ± 0.031	2.362AlaTyr: 2.362 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	1.239CysAla: 1.239 ± 0.03	0.334CysCys: 0.334 ± 0.015	0.879CysAsp: 0.879 ± 0.023	0.75CysGlu: 0.75 ± 0.025	0.752CysPhe: 0.752 ± 0.022	1.566CysGly: 1.566 ± 0.035	0.326CysHis: 0.326 ± 0.016	0.635CysIle: 0.635 ± 0.021	0.46CysLys: 0.46 ± 0.019	1.08CysLeu: 1.08 ± 0.028	0.299CysMet: 0.299 ± 0.014	0.543CysAsn: 0.543 ± 0.019	0.9CysPro: 0.9 ± 0.026	0.297CysGln: 0.297 ± 0.013	1.593CysArg: 1.593 ± 0.038	0.886CysSer: 0.886 ± 0.023	0.673CysThr: 0.673 ± 0.019	0.838CysVal: 0.838 ± 0.022	0.248CysTrp: 0.248 ± 0.012	0.541CysTyr: 0.541 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	5.021AspAla: 5.021 ± 0.062	0.854AspCys: 0.854 ± 0.025	2.526AspAsp: 2.526 ± 0.046	2.973AspGlu: 2.973 ± 0.053	2.882AspPhe: 2.882 ± 0.046	5.425AspGly: 5.425 ± 0.075	0.978AspHis: 0.978 ± 0.025	2.44AspIle: 2.44 ± 0.046	1.868AspLys: 1.868 ± 0.041	4.439AspLeu: 4.439 ± 0.059	0.984AspMet: 0.984 ± 0.027	1.723AspAsn: 1.723 ± 0.038	2.826AspPro: 2.826 ± 0.046	1.234AspGln: 1.234 ± 0.034	4.099AspArg: 4.099 ± 0.058	2.847AspSer: 2.847 ± 0.048	2.146AspThr: 2.146 ± 0.035	2.867AspVal: 2.867 ± 0.053	1.073AspTrp: 1.073 ± 0.027	2.142AspTyr: 2.142 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	6.375GluAla: 6.375 ± 0.075	0.851GluCys: 0.851 ± 0.026	2.047GluAsp: 2.047 ± 0.036	4.046GluGlu: 4.046 ± 0.068	3.436GluPhe: 3.436 ± 0.052	3.264GluGly: 3.264 ± 0.045	1.239GluHis: 1.239 ± 0.031	3.977GluIle: 3.977 ± 0.057	3.957GluLys: 3.957 ± 0.065	8.96GluLeu: 8.96 ± 0.099	1.572GluMet: 1.572 ± 0.033	2.769GluAsn: 2.769 ± 0.043	2.945GluPro: 2.945 ± 0.048	2.471GluGln: 2.471 ± 0.041	4.708GluArg: 4.708 ± 0.063	3.129GluSer: 3.129 ± 0.043	3.47GluThr: 3.47 ± 0.051	4.031GluVal: 4.031 ± 0.058	1.0GluTrp: 1.0 ± 0.026	2.151GluTyr: 2.151 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	4.157PheAla: 4.157 ± 0.057	0.87PheCys: 0.87 ± 0.023	3.137PheAsp: 3.137 ± 0.053	2.583PheGlu: 2.583 ± 0.047	2.135PhePhe: 2.135 ± 0.045	3.775PheGly: 3.775 ± 0.049	1.066PheHis: 1.066 ± 0.032	1.929PheIle: 1.929 ± 0.041	1.427PheLys: 1.427 ± 0.03	4.216PheLeu: 4.216 ± 0.061	0.839PheMet: 0.839 ± 0.023	1.684PheAsn: 1.684 ± 0.038	2.235PhePro: 2.235 ± 0.041	1.3PheGln: 1.3 ± 0.031	4.0PheArg: 4.0 ± 0.06	3.053PheSer: 3.053 ± 0.048	2.685PheThr: 2.685 ± 0.041	2.383PheVal: 2.383 ± 0.04	0.688PheTrp: 0.688 ± 0.022	1.602PheTyr: 1.602 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	6.888GlyAla: 6.888 ± 0.1	1.474GlyCys: 1.474 ± 0.032	4.038GlyAsp: 4.038 ± 0.057	5.337GlyGlu: 5.337 ± 0.054	3.832GlyPhe: 3.832 ± 0.054	6.946GlyGly: 6.946 ± 0.16	1.481GlyHis: 1.481 ± 0.03	4.891GlyIle: 4.891 ± 0.069	4.805GlyLys: 4.805 ± 0.068	6.418GlyLeu: 6.418 ± 0.072	2.206GlyMet: 2.206 ± 0.038	3.332GlyAsn: 3.332 ± 0.073	2.325GlyPro: 2.325 ± 0.039	1.857GlyGln: 1.857 ± 0.034	5.99GlyArg: 5.99 ± 0.072	4.712GlySer: 4.712 ± 0.073	4.323GlyThr: 4.323 ± 0.067	5.702GlyVal: 5.702 ± 0.069	1.418GlyTrp: 1.418 ± 0.038	2.724GlyTyr: 2.724 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	1.593HisAla: 1.593 ± 0.035	0.352HisCys: 0.352 ± 0.016	0.94HisAsp: 0.94 ± 0.027	0.984HisGlu: 0.984 ± 0.024	0.902HisPhe: 0.902 ± 0.026	1.621HisGly: 1.621 ± 0.037	0.46HisHis: 0.46 ± 0.019	0.879HisIle: 0.879 ± 0.02	0.508HisLys: 0.508 ± 0.02	1.785HisLeu: 1.785 ± 0.039	0.293HisMet: 0.293 ± 0.014	0.692HisAsn: 0.692 ± 0.022	1.321HisPro: 1.321 ± 0.028	0.511HisGln: 0.511 ± 0.02	1.405HisArg: 1.405 ± 0.032	1.076HisSer: 1.076 ± 0.027	0.895HisThr: 0.895 ± 0.028	1.027HisVal: 1.027 ± 0.022	0.363HisTrp: 0.363 ± 0.015	0.724HisTyr: 0.724 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.654IleAla: 5.654 ± 0.067	0.734IleCys: 0.734 ± 0.02	3.055IleAsp: 3.055 ± 0.052	3.091IleGlu: 3.091 ± 0.048	2.148IlePhe: 2.148 ± 0.043	4.248IleGly: 4.248 ± 0.064	1.014IleHis: 1.014 ± 0.028	2.248IleIle: 2.248 ± 0.052	1.518IleLys: 1.518 ± 0.035	4.787IleLeu: 4.787 ± 0.066	0.906IleMet: 0.906 ± 0.027	1.633IleAsn: 1.633 ± 0.033	3.054IlePro: 3.054 ± 0.046	1.346IleGln: 1.346 ± 0.028	4.197IleArg: 4.197 ± 0.053	3.056IleSer: 3.056 ± 0.04	2.54IleThr: 2.54 ± 0.047	3.143IleVal: 3.143 ± 0.05	0.664IleTrp: 0.664 ± 0.023	1.539IleTyr: 1.539 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	3.989LysAla: 3.989 ± 0.053	0.474LysCys: 0.474 ± 0.019	1.616LysAsp: 1.616 ± 0.036	2.665LysGlu: 2.665 ± 0.052	1.917LysPhe: 1.917 ± 0.04	2.444LysGly: 2.444 ± 0.046	0.775LysHis: 0.775 ± 0.027	2.606LysIle: 2.606 ± 0.047	2.408LysLys: 2.408 ± 0.049	5.235LysLeu: 5.235 ± 0.059	1.255LysMet: 1.255 ± 0.03	1.699LysAsn: 1.699 ± 0.034	2.292LysPro: 2.292 ± 0.043	1.689LysGln: 1.689 ± 0.038	2.79LysArg: 2.79 ± 0.049	2.333LysSer: 2.333 ± 0.049	2.271LysThr: 2.271 ± 0.048	2.826LysVal: 2.826 ± 0.054	0.509LysTrp: 0.509 ± 0.018	1.402LysTyr: 1.402 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	10.965LeuAla: 10.965 ± 0.108	1.416LeuCys: 1.416 ± 0.031	5.346LeuAsp: 5.346 ± 0.059	6.557LeuGlu: 6.557 ± 0.07	4.366LeuPhe: 4.366 ± 0.055	6.484LeuGly: 6.484 ± 0.078	1.82LeuHis: 1.82 ± 0.036	4.861LeuIle: 4.861 ± 0.062	5.156LeuLys: 5.156 ± 0.066	11.22LeuLeu: 11.22 ± 0.127	1.973LeuMet: 1.973 ± 0.04	3.883LeuAsn: 3.883 ± 0.05	6.555LeuPro: 6.555 ± 0.073	2.682LeuGln: 2.682 ± 0.048	6.912LeuArg: 6.912 ± 0.089	5.52LeuSer: 5.52 ± 0.066	5.479LeuThr: 5.479 ± 0.071	5.944LeuVal: 5.944 ± 0.071	1.261LeuTrp: 1.261 ± 0.035	2.957LeuTyr: 2.957 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.077MetAla: 2.077 ± 0.042	0.238MetCys: 0.238 ± 0.013	0.932MetAsp: 0.932 ± 0.027	1.39MetGlu: 1.39 ± 0.032	0.818MetPhe: 0.818 ± 0.025	1.241MetGly: 1.241 ± 0.029	0.374MetHis: 0.374 ± 0.016	1.258MetIle: 1.258 ± 0.028	1.591MetLys: 1.591 ± 0.034	2.683MetLeu: 2.683 ± 0.039	0.641MetMet: 0.641 ± 0.02	1.036MetAsn: 1.036 ± 0.027	1.293MetPro: 1.293 ± 0.034	0.755MetGln: 0.755 ± 0.025	1.564MetArg: 1.564 ± 0.033	1.22MetSer: 1.22 ± 0.031	1.248MetThr: 1.248 ± 0.028	1.404MetVal: 1.404 ± 0.032	0.25MetTrp: 0.25 ± 0.012	0.495MetTyr: 0.495 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.143AsnAla: 3.143 ± 0.062	0.631AsnCys: 0.631 ± 0.022	1.801AsnAsp: 1.801 ± 0.039	1.666AsnGlu: 1.666 ± 0.037	1.767AsnPhe: 1.767 ± 0.032	3.347AsnGly: 3.347 ± 0.072	0.747AsnHis: 0.747 ± 0.021	1.859AsnIle: 1.859 ± 0.04	1.127AsnLys: 1.127 ± 0.028	3.549AsnLeu: 3.549 ± 0.052	0.792AsnMet: 0.792 ± 0.022	1.371AsnAsn: 1.371 ± 0.041	2.273AsnPro: 2.273 ± 0.038	1.006AsnGln: 1.006 ± 0.025	2.901AsnArg: 2.901 ± 0.045	2.158AsnSer: 2.158 ± 0.043	1.726AsnThr: 1.726 ± 0.047	2.093AsnVal: 2.093 ± 0.039	0.734AsnTrp: 0.734 ± 0.026	1.426AsnTyr: 1.426 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	6.774ProAla: 6.774 ± 0.072	0.574ProCys: 0.574 ± 0.018	3.524ProAsp: 3.524 ± 0.051	6.062ProGlu: 6.062 ± 0.071	2.193ProPhe: 2.193 ± 0.041	5.15ProGly: 5.15 ± 0.069	0.919ProHis: 0.919 ± 0.024	1.516ProIle: 1.516 ± 0.03	1.655ProLys: 1.655 ± 0.034	4.466ProLeu: 4.466 ± 0.056	0.977ProMet: 0.977 ± 0.025	1.437ProAsn: 1.437 ± 0.032	2.561ProPro: 2.561 ± 0.053	1.575ProGln: 1.575 ± 0.037	2.491ProArg: 2.491 ± 0.045	2.198ProSer: 2.198 ± 0.039	1.676ProThr: 1.676 ± 0.03	4.677ProVal: 4.677 ± 0.061	0.708ProTrp: 0.708 ± 0.022	1.509ProTyr: 1.509 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	2.878GlnAla: 2.878 ± 0.047	0.419GlnCys: 0.419 ± 0.017	1.101GlnAsp: 1.101 ± 0.027	1.888GlnGlu: 1.888 ± 0.038	1.248GlnPhe: 1.248 ± 0.025	1.801GlnGly: 1.801 ± 0.033	0.458GlnHis: 0.458 ± 0.017	1.536GlnIle: 1.536 ± 0.03	1.503GlnLys: 1.503 ± 0.039	3.638GlnLeu: 3.638 ± 0.049	0.764GlnMet: 0.764 ± 0.022	0.978GlnAsn: 0.978 ± 0.028	1.577GlnPro: 1.577 ± 0.031	1.188GlnGln: 1.188 ± 0.039	1.684GlnArg: 1.684 ± 0.038	1.466GlnSer: 1.466 ± 0.032	1.324GlnThr: 1.324 ± 0.031	1.912GlnVal: 1.912 ± 0.031	0.392GlnTrp: 0.392 ± 0.016	0.961GlnTyr: 0.961 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	5.292ArgAla: 5.292 ± 0.065	1.056ArgCys: 1.056 ± 0.032	3.512ArgAsp: 3.512 ± 0.053	5.652ArgGlu: 5.652 ± 0.069	3.657ArgPhe: 3.657 ± 0.047	4.189ArgGly: 4.189 ± 0.056	1.602ArgHis: 1.602 ± 0.029	4.515ArgIle: 4.515 ± 0.062	3.643ArgLys: 3.643 ± 0.056	7.863ArgLeu: 7.863 ± 0.081	1.809ArgMet: 1.809 ± 0.034	3.191ArgAsn: 3.191 ± 0.05	3.472ArgPro: 3.472 ± 0.058	2.696ArgGln: 2.696 ± 0.044	6.222ArgArg: 6.222 ± 0.077	3.768ArgSer: 3.768 ± 0.052	3.224ArgThr: 3.224 ± 0.052	3.673ArgVal: 3.673 ± 0.05	1.009ArgTrp: 1.009 ± 0.031	2.485ArgTyr: 2.485 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	5.283SerAla: 5.283 ± 0.064	0.965SerCys: 0.965 ± 0.025	2.899SerAsp: 2.899 ± 0.045	3.225SerGlu: 3.225 ± 0.048	2.577SerPhe: 2.577 ± 0.041	6.205SerGly: 6.205 ± 0.085	0.923SerHis: 0.923 ± 0.024	2.628SerIle: 2.628 ± 0.044	1.661SerLys: 1.661 ± 0.035	4.853SerLeu: 4.853 ± 0.052	1.232SerMet: 1.232 ± 0.029	1.684SerAsn: 1.684 ± 0.041	2.845SerPro: 2.845 ± 0.046	1.352SerGln: 1.352 ± 0.034	3.952SerArg: 3.952 ± 0.053	3.206SerSer: 3.206 ± 0.081	2.44SerThr: 2.44 ± 0.045	3.643SerVal: 3.643 ± 0.055	0.916SerTrp: 0.916 ± 0.025	1.776SerTyr: 1.776 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.244ThrAla: 5.244 ± 0.073	0.583ThrCys: 0.583 ± 0.02	2.464ThrAsp: 2.464 ± 0.036	2.697ThrGlu: 2.697 ± 0.046	2.11ThrPhe: 2.11 ± 0.041	5.092ThrGly: 5.092 ± 0.086	0.761ThrHis: 0.761 ± 0.02	2.287ThrIle: 2.287 ± 0.052	1.164ThrLys: 1.164 ± 0.027	5.485ThrLeu: 5.485 ± 0.066	1.043ThrMet: 1.043 ± 0.026	1.186ThrAsn: 1.186 ± 0.032	3.283ThrPro: 3.283 ± 0.042	1.085ThrGln: 1.085 ± 0.025	2.807ThrArg: 2.807 ± 0.043	2.259ThrSer: 2.259 ± 0.045	2.029ThrThr: 2.029 ± 0.041	4.657ThrVal: 4.657 ± 0.069	0.493ThrTrp: 0.493 ± 0.019	1.293ThrTyr: 1.293 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	5.895ValAla: 5.895 ± 0.069	0.991ValCys: 0.991 ± 0.025	3.204ValAsp: 3.204 ± 0.048	4.279ValGlu: 4.279 ± 0.054	2.922ValPhe: 2.922 ± 0.043	4.07ValGly: 4.07 ± 0.059	0.991ValHis: 0.991 ± 0.025	3.916ValIle: 3.916 ± 0.052	3.196ValLys: 3.196 ± 0.051	6.266ValLeu: 6.266 ± 0.068	1.611ValMet: 1.611 ± 0.038	2.43ValAsn: 2.43 ± 0.047	3.75ValPro: 3.75 ± 0.053	1.607ValGln: 1.607 ± 0.036	4.842ValArg: 4.842 ± 0.058	4.037ValSer: 4.037 ± 0.058	4.01ValThr: 4.01 ± 0.059	4.231ValVal: 4.231 ± 0.062	1.034ValTrp: 1.034 ± 0.029	2.01ValTyr: 2.01 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.96TrpAla: 0.96 ± 0.026	0.251TrpCys: 0.251 ± 0.012	0.71TrpAsp: 0.71 ± 0.023	0.915TrpGlu: 0.915 ± 0.028	0.685TrpPhe: 0.685 ± 0.021	1.166TrpGly: 1.166 ± 0.032	0.35TrpHis: 0.35 ± 0.016	0.732TrpIle: 0.732 ± 0.022	0.938TrpLys: 0.938 ± 0.025	1.455TrpLeu: 1.455 ± 0.036	0.37TrpMet: 0.37 ± 0.016	0.901TrpAsn: 0.901 ± 0.025	0.636TrpPro: 0.636 ± 0.022	0.597TrpGln: 0.597 ± 0.019	1.22TrpArg: 1.22 ± 0.031	0.978TrpSer: 0.978 ± 0.025	0.742TrpThr: 0.742 ± 0.026	0.601TrpVal: 0.601 ± 0.019	0.242TrpTrp: 0.242 ± 0.013	0.463TrpTyr: 0.463 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.838TyrAla: 2.838 ± 0.047	0.596TyrCys: 0.596 ± 0.02	1.767TyrAsp: 1.767 ± 0.034	1.637TyrGlu: 1.637 ± 0.036	1.694TyrPhe: 1.694 ± 0.037	2.648TyrGly: 2.648 ± 0.047	0.691TyrHis: 0.691 ± 0.022	1.282TyrIle: 1.282 ± 0.032	0.913TyrLys: 0.913 ± 0.023	3.3TyrLeu: 3.3 ± 0.048	0.608TyrMet: 0.608 ± 0.016	1.211TyrAsn: 1.211 ± 0.026	1.708TyrPro: 1.708 ± 0.039	1.027TyrGln: 1.027 ± 0.027	3.049TyrArg: 3.049 ± 0.05	1.853TyrSer: 1.853 ± 0.034	1.489TyrThr: 1.489 ± 0.032	1.681TyrVal: 1.681 ± 0.037	0.572TyrTrp: 0.572 ± 0.019	1.174TyrTyr: 1.174 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4059 proteins (1560380 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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