Amino acid dipepetide frequency for Halobacteriovorax marinus (strain ATCC BAA-682 / DSM 15412 / SJ) (Bacteriovorax marinus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.894AlaAla: 3.894 ± 0.1
0.697AlaCys: 0.697 ± 0.028
2.76AlaAsp: 2.76 ± 0.053
3.153AlaGlu: 3.153 ± 0.058
2.61AlaPhe: 2.61 ± 0.05
3.794AlaGly: 3.794 ± 0.077
1.188AlaHis: 1.188 ± 0.038
4.4AlaIle: 4.4 ± 0.074
5.175AlaLys: 5.175 ± 0.085
6.307AlaLeu: 6.307 ± 0.077
1.542AlaMet: 1.542 ± 0.045
2.924AlaAsn: 2.924 ± 0.068
2.021AlaPro: 2.021 ± 0.051
2.167AlaGln: 2.167 ± 0.049
2.389AlaArg: 2.389 ± 0.051
4.424AlaSer: 4.424 ± 0.072
3.241AlaThr: 3.241 ± 0.075
3.185AlaVal: 3.185 ± 0.057
0.49AlaTrp: 0.49 ± 0.022
1.815AlaTyr: 1.815 ± 0.042
0.0AlaXaa: 0.0 ± 0.0
Cys
0.659CysAla: 0.659 ± 0.027
0.141CysCys: 0.141 ± 0.012
0.686CysAsp: 0.686 ± 0.028
0.781CysGlu: 0.781 ± 0.028
0.59CysPhe: 0.59 ± 0.023
0.757CysGly: 0.757 ± 0.028
0.32CysHis: 0.32 ± 0.019
0.651CysIle: 0.651 ± 0.026
0.671CysLys: 0.671 ± 0.026
1.11CysLeu: 1.11 ± 0.035
0.224CysMet: 0.224 ± 0.015
0.498CysAsn: 0.498 ± 0.024
0.484CysPro: 0.484 ± 0.027
0.348CysGln: 0.348 ± 0.018
0.459CysArg: 0.459 ± 0.022
1.014CysSer: 1.014 ± 0.034
0.557CysThr: 0.557 ± 0.03
0.617CysVal: 0.617 ± 0.026
0.106CysTrp: 0.106 ± 0.01
0.376CysTyr: 0.376 ± 0.019
0.0CysXaa: 0.0 ± 0.0
Asp
2.788AspAla: 2.788 ± 0.052
0.605AspCys: 0.605 ± 0.022
2.92AspAsp: 2.92 ± 0.069
4.401AspGlu: 4.401 ± 0.077
3.529AspPhe: 3.529 ± 0.061
3.362AspGly: 3.362 ± 0.07
1.218AspHis: 1.218 ± 0.036
4.607AspIle: 4.607 ± 0.07
4.006AspLys: 4.006 ± 0.071
5.957AspLeu: 5.957 ± 0.091
1.135AspMet: 1.135 ± 0.032
2.529AspAsn: 2.529 ± 0.056
1.768AspPro: 1.768 ± 0.046
1.973AspGln: 1.973 ± 0.04
2.221AspArg: 2.221 ± 0.051
3.962AspSer: 3.962 ± 0.074
2.338AspThr: 2.338 ± 0.058
3.045AspVal: 3.045 ± 0.058
0.602AspTrp: 0.602 ± 0.022
2.466AspTyr: 2.466 ± 0.057
0.0AspXaa: 0.0 ± 0.0
Glu
3.889GluAla: 3.889 ± 0.065
0.681GluCys: 0.681 ± 0.023
4.152GluAsp: 4.152 ± 0.076
6.215GluGlu: 6.215 ± 0.126
3.631GluPhe: 3.631 ± 0.063
3.909GluGly: 3.909 ± 0.066
1.201GluHis: 1.201 ± 0.036
5.888GluIle: 5.888 ± 0.088
6.6GluLys: 6.6 ± 0.096
7.742GluLeu: 7.742 ± 0.11
1.818GluMet: 1.818 ± 0.042
4.347GluAsn: 4.347 ± 0.07
1.319GluPro: 1.319 ± 0.043
2.272GluGln: 2.272 ± 0.047
3.221GluArg: 3.221 ± 0.059
5.203GluSer: 5.203 ± 0.065
3.196GluThr: 3.196 ± 0.059
5.361GluVal: 5.361 ± 0.08
0.593GluTrp: 0.593 ± 0.022
2.468GluTyr: 2.468 ± 0.054
0.0GluXaa: 0.0 ± 0.0
Phe
2.771PheAla: 2.771 ± 0.056
0.638PheCys: 0.638 ± 0.023
2.998PheAsp: 2.998 ± 0.055
3.458PheGlu: 3.458 ± 0.054
2.918PhePhe: 2.918 ± 0.072
3.101PheGly: 3.101 ± 0.066
1.03PheHis: 1.03 ± 0.032
3.979PheIle: 3.979 ± 0.081
4.224PheLys: 4.224 ± 0.071
5.303PheLeu: 5.303 ± 0.097
1.12PheMet: 1.12 ± 0.032
3.089PheAsn: 3.089 ± 0.053
1.658PhePro: 1.658 ± 0.042
1.505PheGln: 1.505 ± 0.038
1.783PheArg: 1.783 ± 0.035
4.809PheSer: 4.809 ± 0.079
2.669PheThr: 2.669 ± 0.055
2.715PheVal: 2.715 ± 0.066
0.518PheTrp: 0.518 ± 0.025
2.088PheTyr: 2.088 ± 0.046
0.0PheXaa: 0.0 ± 0.0
Gly
4.098GlyAla: 4.098 ± 0.076
0.69GlyCys: 0.69 ± 0.03
3.46GlyAsp: 3.46 ± 0.062
4.525GlyGlu: 4.525 ± 0.071
2.962GlyPhe: 2.962 ± 0.061
4.266GlyGly: 4.266 ± 0.099
1.55GlyHis: 1.55 ± 0.039
4.548GlyIle: 4.548 ± 0.063
4.533GlyLys: 4.533 ± 0.075
5.89GlyLeu: 5.89 ± 0.081
1.385GlyMet: 1.385 ± 0.045
2.693GlyAsn: 2.693 ± 0.054
1.638GlyPro: 1.638 ± 0.039
1.837GlyGln: 1.837 ± 0.045
2.565GlyArg: 2.565 ± 0.047
4.248GlySer: 4.248 ± 0.087
3.071GlyThr: 3.071 ± 0.068
4.555GlyVal: 4.555 ± 0.07
0.517GlyTrp: 0.517 ± 0.025
2.074GlyTyr: 2.074 ± 0.04
0.0GlyXaa: 0.0 ± 0.0
His
0.976HisAla: 0.976 ± 0.033
0.289HisCys: 0.289 ± 0.018
0.961HisAsp: 0.961 ± 0.032
1.154HisGlu: 1.154 ± 0.032
1.227HisPhe: 1.227 ± 0.035
1.215HisGly: 1.215 ± 0.04
0.544HisHis: 0.544 ± 0.026
1.373HisIle: 1.373 ± 0.033
1.188HisLys: 1.188 ± 0.033
1.949HisLeu: 1.949 ± 0.051
0.416HisMet: 0.416 ± 0.019
0.844HisAsn: 0.844 ± 0.031
0.88HisPro: 0.88 ± 0.033
0.672HisGln: 0.672 ± 0.025
0.821HisArg: 0.821 ± 0.026
1.483HisSer: 1.483 ± 0.038
0.87HisThr: 0.87 ± 0.028
0.879HisVal: 0.879 ± 0.033
0.23HisTrp: 0.23 ± 0.016
0.852HisTyr: 0.852 ± 0.026
0.0HisXaa: 0.0 ± 0.0
Ile
4.587IleAla: 4.587 ± 0.068
0.865IleCys: 0.865 ± 0.032
4.579IleAsp: 4.579 ± 0.073
5.752IleGlu: 5.752 ± 0.083
3.963IlePhe: 3.963 ± 0.079
4.504IleGly: 4.504 ± 0.077
1.498IleHis: 1.498 ± 0.039
5.342IleIle: 5.342 ± 0.095
5.589IleLys: 5.589 ± 0.083
7.485IleLeu: 7.485 ± 0.103
1.338IleMet: 1.338 ± 0.037
3.948IleAsn: 3.948 ± 0.071
2.876IlePro: 2.876 ± 0.058
2.355IleGln: 2.355 ± 0.047
2.782IleArg: 2.782 ± 0.058
6.514IleSer: 6.514 ± 0.08
3.818IleThr: 3.818 ± 0.06
4.236IleVal: 4.236 ± 0.074
0.59IleTrp: 0.59 ± 0.022
2.644IleTyr: 2.644 ± 0.052
0.0IleXaa: 0.0 ± 0.0
Lys
4.531LysAla: 4.531 ± 0.07
0.682LysCys: 0.682 ± 0.029
4.76LysAsp: 4.76 ± 0.085
7.269LysGlu: 7.269 ± 0.093
3.648LysPhe: 3.648 ± 0.07
4.467LysGly: 4.467 ± 0.061
1.159LysHis: 1.159 ± 0.036
6.085LysIle: 6.085 ± 0.075
8.388LysLys: 8.388 ± 0.152
7.403LysLeu: 7.403 ± 0.097
1.917LysMet: 1.917 ± 0.043
4.802LysAsn: 4.802 ± 0.082
1.792LysPro: 1.792 ± 0.045
1.939LysGln: 1.939 ± 0.042
3.675LysArg: 3.675 ± 0.063
6.279LysSer: 6.279 ± 0.076
3.889LysThr: 3.889 ± 0.068
5.734LysVal: 5.734 ± 0.088
0.775LysTrp: 0.775 ± 0.029
3.095LysTyr: 3.095 ± 0.056
0.0LysXaa: 0.0 ± 0.0
Leu
5.937LeuAla: 5.937 ± 0.085
1.093LeuCys: 1.093 ± 0.033
5.56LeuAsp: 5.56 ± 0.076
7.627LeuGlu: 7.627 ± 0.104
4.898LeuPhe: 4.898 ± 0.099
6.283LeuGly: 6.283 ± 0.087
1.536LeuHis: 1.536 ± 0.038
7.297LeuIle: 7.297 ± 0.095
8.646LeuLys: 8.646 ± 0.102
9.15LeuLeu: 9.15 ± 0.124
2.238LeuMet: 2.238 ± 0.045
5.612LeuAsn: 5.612 ± 0.079
3.329LeuPro: 3.329 ± 0.058
2.615LeuGln: 2.615 ± 0.052
4.078LeuArg: 4.078 ± 0.065
9.055LeuSer: 9.055 ± 0.1
5.056LeuThr: 5.056 ± 0.068
5.514LeuVal: 5.514 ± 0.08
0.775LeuTrp: 0.775 ± 0.034
3.014LeuTyr: 3.014 ± 0.06
0.0LeuXaa: 0.0 ± 0.0
Met
1.8MetAla: 1.8 ± 0.043
0.189MetCys: 0.189 ± 0.014
1.175MetAsp: 1.175 ± 0.038
1.355MetGlu: 1.355 ± 0.033
0.776MetPhe: 0.776 ± 0.029
1.581MetGly: 1.581 ± 0.048
0.29MetHis: 0.29 ± 0.014
1.597MetIle: 1.597 ± 0.042
2.389MetLys: 2.389 ± 0.049
1.726MetLeu: 1.726 ± 0.042
0.602MetMet: 0.602 ± 0.025
1.44MetAsn: 1.44 ± 0.04
0.757MetPro: 0.757 ± 0.028
0.64MetGln: 0.64 ± 0.027
1.034MetArg: 1.034 ± 0.032
1.93MetSer: 1.93 ± 0.038
1.254MetThr: 1.254 ± 0.037
1.178MetVal: 1.178 ± 0.035
0.172MetTrp: 0.172 ± 0.014
0.492MetTyr: 0.492 ± 0.021
0.0MetXaa: 0.0 ± 0.0
Asn
2.646AsnAla: 2.646 ± 0.064
0.648AsnCys: 0.648 ± 0.026
2.749AsnAsp: 2.749 ± 0.058
3.713AsnGlu: 3.713 ± 0.067
3.241AsnPhe: 3.241 ± 0.05
3.103AsnGly: 3.103 ± 0.073
0.958AsnHis: 0.958 ± 0.028
4.474AsnIle: 4.474 ± 0.068
3.871AsnLys: 3.871 ± 0.068
5.49AsnLeu: 5.49 ± 0.076
1.072AsnMet: 1.072 ± 0.034
2.627AsnAsn: 2.627 ± 0.064
2.117AsnPro: 2.117 ± 0.047
1.659AsnGln: 1.659 ± 0.044
2.09AsnArg: 2.09 ± 0.045
4.283AsnSer: 4.283 ± 0.072
2.595AsnThr: 2.595 ± 0.062
2.557AsnVal: 2.557 ± 0.056
0.578AsnTrp: 0.578 ± 0.026
2.35AsnTyr: 2.35 ± 0.046
0.0AsnXaa: 0.0 ± 0.0
Pro
1.729ProAla: 1.729 ± 0.044
0.283ProCys: 0.283 ± 0.015
1.561ProAsp: 1.561 ± 0.037
2.437ProGlu: 2.437 ± 0.051
1.796ProPhe: 1.796 ± 0.044
1.873ProGly: 1.873 ± 0.049
0.65ProHis: 0.65 ± 0.025
2.442ProIle: 2.442 ± 0.048
2.449ProLys: 2.449 ± 0.052
3.17ProLeu: 3.17 ± 0.056
0.749ProMet: 0.749 ± 0.025
1.623ProAsn: 1.623 ± 0.044
0.804ProPro: 0.804 ± 0.029
0.912ProGln: 0.912 ± 0.034
1.181ProArg: 1.181 ± 0.039
2.552ProSer: 2.552 ± 0.053
1.742ProThr: 1.742 ± 0.047
2.095ProVal: 2.095 ± 0.045
0.347ProTrp: 0.347 ± 0.019
1.218ProTyr: 1.218 ± 0.036
0.0ProXaa: 0.0 ± 0.0
Gln
1.918GlnAla: 1.918 ± 0.042
0.31GlnCys: 0.31 ± 0.019
1.512GlnAsp: 1.512 ± 0.042
2.206GlnGlu: 2.206 ± 0.049
1.454GlnPhe: 1.454 ± 0.036
1.746GlnGly: 1.746 ± 0.051
0.4GlnHis: 0.4 ± 0.018
2.304GlnIle: 2.304 ± 0.039
2.538GlnLys: 2.538 ± 0.054
2.788GlnLeu: 2.788 ± 0.053
0.787GlnMet: 0.787 ± 0.028
1.586GlnAsn: 1.586 ± 0.043
0.55GlnPro: 0.55 ± 0.022
0.841GlnGln: 0.841 ± 0.03
1.582GlnArg: 1.582 ± 0.042
2.314GlnSer: 2.314 ± 0.049
1.546GlnThr: 1.546 ± 0.038
2.079GlnVal: 2.079 ± 0.044
0.28GlnTrp: 0.28 ± 0.017
1.118GlnTyr: 1.118 ± 0.032
0.0GlnXaa: 0.0 ± 0.0
Arg
2.465ArgAla: 2.465 ± 0.049
0.372ArgCys: 0.372 ± 0.019
2.596ArgAsp: 2.596 ± 0.055
3.807ArgGlu: 3.807 ± 0.07
2.0ArgPhe: 2.0 ± 0.044
2.475ArgGly: 2.475 ± 0.05
0.655ArgHis: 0.655 ± 0.024
2.989ArgIle: 2.989 ± 0.062
3.201ArgLys: 3.201 ± 0.062
3.524ArgLeu: 3.524 ± 0.06
1.048ArgMet: 1.048 ± 0.031
2.205ArgAsn: 2.205 ± 0.05
1.374ArgPro: 1.374 ± 0.036
0.97ArgGln: 0.97 ± 0.028
1.765ArgArg: 1.765 ± 0.047
2.806ArgSer: 2.806 ± 0.047
1.862ArgThr: 1.862 ± 0.04
3.054ArgVal: 3.054 ± 0.056
0.363ArgTrp: 0.363 ± 0.018
1.499ArgTyr: 1.499 ± 0.043
0.0ArgXaa: 0.0 ± 0.0
Ser
4.479SerAla: 4.479 ± 0.064
1.073SerCys: 1.073 ± 0.039
4.246SerAsp: 4.246 ± 0.073
5.364SerGlu: 5.364 ± 0.076
4.817SerPhe: 4.817 ± 0.076
4.88SerGly: 4.88 ± 0.081
1.559SerHis: 1.559 ± 0.042
5.975SerIle: 5.975 ± 0.075
6.598SerLys: 6.598 ± 0.081
8.662SerLeu: 8.662 ± 0.109
1.749SerMet: 1.749 ± 0.038
4.033SerAsn: 4.033 ± 0.076
2.476SerPro: 2.476 ± 0.05
2.204SerGln: 2.204 ± 0.048
3.071SerArg: 3.071 ± 0.062
6.798SerSer: 6.798 ± 0.099
3.964SerThr: 3.964 ± 0.07
4.26SerVal: 4.26 ± 0.071
0.779SerTrp: 0.779 ± 0.031
3.046SerTyr: 3.046 ± 0.058
0.0SerXaa: 0.0 ± 0.0
Thr
2.714ThrAla: 2.714 ± 0.069
0.554ThrCys: 0.554 ± 0.023
2.438ThrAsp: 2.438 ± 0.067
2.935ThrGlu: 2.935 ± 0.058
2.647ThrPhe: 2.647 ± 0.048
3.257ThrGly: 3.257 ± 0.07
1.08ThrHis: 1.08 ± 0.036
3.773ThrIle: 3.773 ± 0.077
3.921ThrLys: 3.921 ± 0.071
5.516ThrLeu: 5.516 ± 0.082
1.006ThrMet: 1.006 ± 0.033
2.542ThrAsn: 2.542 ± 0.064
2.318ThrPro: 2.318 ± 0.056
1.564ThrGln: 1.564 ± 0.044
1.915ThrArg: 1.915 ± 0.048
3.947ThrSer: 3.947 ± 0.074
2.778ThrThr: 2.778 ± 0.065
2.593ThrVal: 2.593 ± 0.059
0.458ThrTrp: 0.458 ± 0.02
1.879ThrTyr: 1.879 ± 0.05
0.0ThrXaa: 0.0 ± 0.0
Val
3.93ValAla: 3.93 ± 0.076
0.641ValCys: 0.641 ± 0.027
3.821ValAsp: 3.821 ± 0.058
4.641ValGlu: 4.641 ± 0.061
2.955ValPhe: 2.955 ± 0.057
3.695ValGly: 3.695 ± 0.072
1.073ValHis: 1.073 ± 0.034
4.325ValIle: 4.325 ± 0.072
4.75ValLys: 4.75 ± 0.074
5.474ValLeu: 5.474 ± 0.079
1.252ValMet: 1.252 ± 0.035
3.075ValAsn: 3.075 ± 0.062
1.847ValPro: 1.847 ± 0.045
1.804ValGln: 1.804 ± 0.035
2.304ValArg: 2.304 ± 0.043
4.697ValSer: 4.697 ± 0.066
3.082ValThr: 3.082 ± 0.054
3.808ValVal: 3.808 ± 0.074
0.481ValTrp: 0.481 ± 0.024
1.908ValTyr: 1.908 ± 0.044
0.0ValXaa: 0.0 ± 0.0
Trp
0.589TrpAla: 0.589 ± 0.029
0.104TrpCys: 0.104 ± 0.01
0.525TrpAsp: 0.525 ± 0.023
0.52TrpGlu: 0.52 ± 0.025
0.451TrpPhe: 0.451 ± 0.023
0.674TrpGly: 0.674 ± 0.027
0.206TrpHis: 0.206 ± 0.013
0.666TrpIle: 0.666 ± 0.027
0.775TrpLys: 0.775 ± 0.027
0.79TrpLeu: 0.79 ± 0.029
0.245TrpMet: 0.245 ± 0.014
0.525TrpAsn: 0.525 ± 0.02
0.293TrpPro: 0.293 ± 0.018
0.322TrpGln: 0.322 ± 0.017
0.4TrpArg: 0.4 ± 0.022
0.721TrpSer: 0.721 ± 0.027
0.451TrpThr: 0.451 ± 0.023
0.508TrpVal: 0.508 ± 0.019
0.13TrpTrp: 0.13 ± 0.012
0.299TrpTyr: 0.299 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.776TyrAla: 1.776 ± 0.041
0.496TyrCys: 0.496 ± 0.023
1.972TyrAsp: 1.972 ± 0.041
2.393TyrGlu: 2.393 ± 0.051
2.261TyrPhe: 2.261 ± 0.055
2.164TyrGly: 2.164 ± 0.041
0.708TyrHis: 0.708 ± 0.024
2.55TyrIle: 2.55 ± 0.046
2.776TyrLys: 2.776 ± 0.054
3.877TyrLeu: 3.877 ± 0.072
0.734TyrMet: 0.734 ± 0.03
1.881TyrAsn: 1.881 ± 0.041
1.311TyrPro: 1.311 ± 0.039
1.257TyrGln: 1.257 ± 0.038
1.692TyrArg: 1.692 ± 0.038
2.997TyrSer: 2.997 ± 0.061
1.855TyrThr: 1.855 ± 0.045
1.592TyrVal: 1.592 ± 0.038
0.409TyrTrp: 0.409 ± 0.018
1.447TyrTyr: 1.447 ± 0.04
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3230 proteins (1060232 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski