Amino acid dipepetide frequency for Caballeronia insecticola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.072AlaAla: 17.072 ± 0.136
1.415AlaCys: 1.415 ± 0.029
6.658AlaAsp: 6.658 ± 0.063
5.887AlaGlu: 5.887 ± 0.063
4.658AlaPhe: 4.658 ± 0.052
10.042AlaGly: 10.042 ± 0.088
3.077AlaHis: 3.077 ± 0.048
5.981AlaIle: 5.981 ± 0.063
4.124AlaLys: 4.124 ± 0.062
14.48AlaLeu: 14.48 ± 0.123
3.524AlaMet: 3.524 ± 0.042
3.449AlaAsn: 3.449 ± 0.046
6.057AlaPro: 6.057 ± 0.07
5.303AlaGln: 5.303 ± 0.061
9.641AlaArg: 9.641 ± 0.077
7.906AlaSer: 7.906 ± 0.067
6.252AlaThr: 6.252 ± 0.067
8.558AlaVal: 8.558 ± 0.082
1.688AlaTrp: 1.688 ± 0.03
2.785AlaTyr: 2.785 ± 0.042
0.0AlaXaa: 0.0 ± 0.0
Cys
1.337CysAla: 1.337 ± 0.026
0.131CysCys: 0.131 ± 0.008
0.563CysAsp: 0.563 ± 0.017
0.508CysGlu: 0.508 ± 0.017
0.352CysPhe: 0.352 ± 0.015
1.005CysGly: 1.005 ± 0.025
0.243CysHis: 0.243 ± 0.011
0.453CysIle: 0.453 ± 0.016
0.252CysLys: 0.252 ± 0.011
0.767CysLeu: 0.767 ± 0.019
0.219CysMet: 0.219 ± 0.01
0.249CysAsn: 0.249 ± 0.012
0.437CysPro: 0.437 ± 0.017
0.197CysGln: 0.197 ± 0.01
0.587CysArg: 0.587 ± 0.02
0.527CysSer: 0.527 ± 0.018
0.477CysThr: 0.477 ± 0.015
0.818CysVal: 0.818 ± 0.021
0.116CysTrp: 0.116 ± 0.007
0.234CysTyr: 0.234 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
8.415AspAla: 8.415 ± 0.082
0.473AspCys: 0.473 ± 0.015
3.369AspAsp: 3.369 ± 0.045
3.595AspGlu: 3.595 ± 0.048
2.021AspPhe: 2.021 ± 0.031
4.5AspGly: 4.5 ± 0.044
1.174AspHis: 1.174 ± 0.025
2.855AspIle: 2.855 ± 0.04
1.618AspLys: 1.618 ± 0.031
5.023AspLeu: 5.023 ± 0.053
1.291AspMet: 1.291 ± 0.025
1.303AspAsn: 1.303 ± 0.029
2.828AspPro: 2.828 ± 0.039
1.499AspGln: 1.499 ± 0.027
3.374AspArg: 3.374 ± 0.041
2.483AspSer: 2.483 ± 0.037
2.872AspThr: 2.872 ± 0.04
4.427AspVal: 4.427 ± 0.048
0.891AspTrp: 0.891 ± 0.022
1.502AspTyr: 1.502 ± 0.028
0.0AspXaa: 0.0 ± 0.0
Glu
6.573GluAla: 6.573 ± 0.073
0.423GluCys: 0.423 ± 0.015
2.126GluAsp: 2.126 ± 0.029
2.495GluGlu: 2.495 ± 0.043
1.829GluPhe: 1.829 ± 0.029
3.445GluGly: 3.445 ± 0.041
1.502GluHis: 1.502 ± 0.034
2.717GluIle: 2.717 ± 0.041
1.87GluLys: 1.87 ± 0.034
5.268GluLeu: 5.268 ± 0.055
1.249GluMet: 1.249 ± 0.023
1.44GluAsn: 1.44 ± 0.028
2.455GluPro: 2.455 ± 0.037
2.218GluGln: 2.218 ± 0.04
5.099GluArg: 5.099 ± 0.063
2.763GluSer: 2.763 ± 0.036
2.996GluThr: 2.996 ± 0.036
3.282GluVal: 3.282 ± 0.043
0.746GluTrp: 0.746 ± 0.019
1.134GluTyr: 1.134 ± 0.026
0.0GluXaa: 0.0 ± 0.001
Phe
4.998PheAla: 4.998 ± 0.055
0.445PheCys: 0.445 ± 0.016
2.889PheAsp: 2.889 ± 0.039
2.1PheGlu: 2.1 ± 0.037
1.557PhePhe: 1.557 ± 0.03
3.845PheGly: 3.845 ± 0.044
0.777PheHis: 0.777 ± 0.018
1.754PheIle: 1.754 ± 0.032
1.087PheLys: 1.087 ± 0.026
3.063PheLeu: 3.063 ± 0.045
0.836PheMet: 0.836 ± 0.023
1.157PheAsn: 1.157 ± 0.024
1.615PhePro: 1.615 ± 0.029
0.978PheGln: 0.978 ± 0.022
2.065PheArg: 2.065 ± 0.029
2.317PheSer: 2.317 ± 0.032
1.99PheThr: 1.99 ± 0.033
3.246PheVal: 3.246 ± 0.041
0.526PheTrp: 0.526 ± 0.019
0.977PheTyr: 0.977 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
9.669GlyAla: 9.669 ± 0.085
0.848GlyCys: 0.848 ± 0.02
3.954GlyAsp: 3.954 ± 0.047
4.189GlyGlu: 4.189 ± 0.048
3.541GlyPhe: 3.541 ± 0.047
6.575GlyGly: 6.575 ± 0.071
1.888GlyHis: 1.888 ± 0.031
4.519GlyIle: 4.519 ± 0.053
3.134GlyLys: 3.134 ± 0.041
7.829GlyLeu: 7.829 ± 0.065
2.33GlyMet: 2.33 ± 0.036
2.221GlyAsn: 2.221 ± 0.04
2.869GlyPro: 2.869 ± 0.037
2.509GlyGln: 2.509 ± 0.042
5.271GlyArg: 5.271 ± 0.061
4.382GlySer: 4.382 ± 0.058
4.442GlyThr: 4.442 ± 0.057
6.737GlyVal: 6.737 ± 0.058
1.311GlyTrp: 1.311 ± 0.025
2.307GlyTyr: 2.307 ± 0.033
0.0GlyXaa: 0.0 ± 0.0
His
3.347HisAla: 3.347 ± 0.049
0.281HisCys: 0.281 ± 0.012
1.466HisAsp: 1.466 ± 0.027
1.259HisGlu: 1.259 ± 0.027
0.982HisPhe: 0.982 ± 0.025
2.183HisGly: 2.183 ± 0.038
0.642HisHis: 0.642 ± 0.019
0.965HisIle: 0.965 ± 0.023
0.537HisLys: 0.537 ± 0.018
2.146HisLeu: 2.146 ± 0.035
0.572HisMet: 0.572 ± 0.016
0.497HisAsn: 0.497 ± 0.014
1.382HisPro: 1.382 ± 0.03
0.604HisGln: 0.604 ± 0.021
1.559HisArg: 1.559 ± 0.033
1.115HisSer: 1.115 ± 0.024
1.098HisThr: 1.098 ± 0.024
1.78HisVal: 1.78 ± 0.031
0.384HisTrp: 0.384 ± 0.013
0.663HisTyr: 0.663 ± 0.018
0.0HisXaa: 0.0 ± 0.0
Ile
7.576IleAla: 7.576 ± 0.07
0.454IleCys: 0.454 ± 0.014
3.901IleAsp: 3.901 ± 0.042
3.485IleGlu: 3.485 ± 0.041
1.562IlePhe: 1.562 ± 0.03
5.161IleGly: 5.161 ± 0.057
0.914IleHis: 0.914 ± 0.021
1.754IleIle: 1.754 ± 0.034
1.389IleLys: 1.389 ± 0.025
3.388IleLeu: 3.388 ± 0.046
0.834IleMet: 0.834 ± 0.021
1.41IleAsn: 1.41 ± 0.03
2.105IlePro: 2.105 ± 0.038
1.215IleGln: 1.215 ± 0.025
2.758IleArg: 2.758 ± 0.036
2.505IleSer: 2.505 ± 0.036
2.354IleThr: 2.354 ± 0.035
4.835IleVal: 4.835 ± 0.052
0.506IleTrp: 0.506 ± 0.016
1.078IleTyr: 1.078 ± 0.024
0.0IleXaa: 0.0 ± 0.0
Lys
3.524LysAla: 3.524 ± 0.054
0.181LysCys: 0.181 ± 0.01
1.526LysAsp: 1.526 ± 0.029
1.519LysGlu: 1.519 ± 0.03
0.962LysPhe: 0.962 ± 0.023
2.201LysGly: 2.201 ± 0.034
0.804LysHis: 0.804 ± 0.02
1.66LysIle: 1.66 ± 0.033
1.45LysLys: 1.45 ± 0.039
3.462LysLeu: 3.462 ± 0.049
0.832LysMet: 0.832 ± 0.023
0.982LysAsn: 0.982 ± 0.025
2.064LysPro: 2.064 ± 0.032
1.283LysGln: 1.283 ± 0.028
2.643LysArg: 2.643 ± 0.036
1.908LysSer: 1.908 ± 0.034
1.968LysThr: 1.968 ± 0.036
2.251LysVal: 2.251 ± 0.038
0.399LysTrp: 0.399 ± 0.014
0.694LysTyr: 0.694 ± 0.022
0.0LysXaa: 0.0 ± 0.0
Leu
13.997LeuAla: 13.997 ± 0.109
0.996LeuCys: 0.996 ± 0.023
6.138LeuAsp: 6.138 ± 0.061
4.758LeuGlu: 4.758 ± 0.05
3.608LeuPhe: 3.608 ± 0.053
7.909LeuGly: 7.909 ± 0.073
2.209LeuHis: 2.209 ± 0.034
4.818LeuIle: 4.818 ± 0.055
3.437LeuLys: 3.437 ± 0.046
9.574LeuLeu: 9.574 ± 0.104
2.309LeuMet: 2.309 ± 0.036
2.746LeuAsn: 2.746 ± 0.042
5.517LeuPro: 5.517 ± 0.055
3.109LeuGln: 3.109 ± 0.04
6.822LeuArg: 6.822 ± 0.066
6.185LeuSer: 6.185 ± 0.061
5.435LeuThr: 5.435 ± 0.055
7.319LeuVal: 7.319 ± 0.071
1.08LeuTrp: 1.08 ± 0.024
2.133LeuTyr: 2.133 ± 0.034
0.0LeuXaa: 0.0 ± 0.0
Met
2.512MetAla: 2.512 ± 0.032
0.202MetCys: 0.202 ± 0.009
0.981MetAsp: 0.981 ± 0.023
1.004MetGlu: 1.004 ± 0.022
0.867MetPhe: 0.867 ± 0.023
1.601MetGly: 1.601 ± 0.032
0.652MetHis: 0.652 ± 0.019
1.296MetIle: 1.296 ± 0.025
1.126MetLys: 1.126 ± 0.024
2.874MetLeu: 2.874 ± 0.044
0.672MetMet: 0.672 ± 0.018
1.025MetAsn: 1.025 ± 0.022
1.551MetPro: 1.551 ± 0.033
1.067MetGln: 1.067 ± 0.025
1.987MetArg: 1.987 ± 0.034
1.905MetSer: 1.905 ± 0.028
1.702MetThr: 1.702 ± 0.028
1.449MetVal: 1.449 ± 0.028
0.23MetTrp: 0.23 ± 0.012
0.422MetTyr: 0.422 ± 0.016
0.0MetXaa: 0.0 ± 0.0
Asn
3.825AsnAla: 3.825 ± 0.052
0.264AsnCys: 0.264 ± 0.012
1.557AsnAsp: 1.557 ± 0.037
1.407AsnGlu: 1.407 ± 0.027
1.025AsnPhe: 1.025 ± 0.025
2.592AsnGly: 2.592 ± 0.047
0.518AsnHis: 0.518 ± 0.017
1.306AsnIle: 1.306 ± 0.024
0.726AsnLys: 0.726 ± 0.022
2.689AsnLeu: 2.689 ± 0.036
0.639AsnMet: 0.639 ± 0.017
0.815AsnAsn: 0.815 ± 0.026
1.757AsnPro: 1.757 ± 0.03
0.881AsnGln: 0.881 ± 0.024
1.826AsnArg: 1.826 ± 0.033
1.304AsnSer: 1.304 ± 0.03
1.491AsnThr: 1.491 ± 0.032
2.34AsnVal: 2.34 ± 0.034
0.424AsnTrp: 0.424 ± 0.014
0.724AsnTyr: 0.724 ± 0.021
0.0AsnXaa: 0.0 ± 0.0
Pro
6.249ProAla: 6.249 ± 0.059
0.359ProCys: 0.359 ± 0.013
3.233ProAsp: 3.233 ± 0.042
3.006ProGlu: 3.006 ± 0.045
1.96ProPhe: 1.96 ± 0.034
3.951ProGly: 3.951 ± 0.041
1.283ProHis: 1.283 ± 0.027
2.065ProIle: 2.065 ± 0.031
1.575ProLys: 1.575 ± 0.025
5.022ProLeu: 5.022 ± 0.055
1.163ProMet: 1.163 ± 0.024
1.48ProAsn: 1.48 ± 0.03
2.408ProPro: 2.408 ± 0.046
1.816ProGln: 1.816 ± 0.033
2.926ProArg: 2.926 ± 0.04
2.878ProSer: 2.878 ± 0.038
2.4ProThr: 2.4 ± 0.039
4.168ProVal: 4.168 ± 0.056
0.641ProTrp: 0.641 ± 0.017
1.247ProTyr: 1.247 ± 0.024
0.0ProXaa: 0.0 ± 0.0
Gln
4.328GlnAla: 4.328 ± 0.052
0.273GlnCys: 0.273 ± 0.011
1.34GlnAsp: 1.34 ± 0.028
1.351GlnGlu: 1.351 ± 0.024
1.233GlnPhe: 1.233 ± 0.025
2.403GlnGly: 2.403 ± 0.035
0.843GlnHis: 0.843 ± 0.02
1.958GlnIle: 1.958 ± 0.029
1.197GlnLys: 1.197 ± 0.026
3.369GlnLeu: 3.369 ± 0.046
1.016GlnMet: 1.016 ± 0.022
0.959GlnAsn: 0.959 ± 0.027
1.813GlnPro: 1.813 ± 0.036
1.607GlnGln: 1.607 ± 0.043
2.687GlnArg: 2.687 ± 0.041
2.061GlnSer: 2.061 ± 0.035
2.022GlnThr: 2.022 ± 0.038
2.245GlnVal: 2.245 ± 0.035
0.541GlnTrp: 0.541 ± 0.014
0.86GlnTyr: 0.86 ± 0.021
0.0GlnXaa: 0.0 ± 0.0
Arg
8.941ArgAla: 8.941 ± 0.082
0.596ArgCys: 0.596 ± 0.017
4.057ArgAsp: 4.057 ± 0.044
4.459ArgGlu: 4.459 ± 0.053
3.103ArgPhe: 3.103 ± 0.037
4.72ArgGly: 4.72 ± 0.052
1.9ArgHis: 1.9 ± 0.03
3.791ArgIle: 3.791 ± 0.049
2.09ArgLys: 2.09 ± 0.033
6.971ArgLeu: 6.971 ± 0.068
1.98ArgMet: 1.98 ± 0.025
1.879ArgAsn: 1.879 ± 0.032
2.917ArgPro: 2.917 ± 0.042
2.288ArgGln: 2.288 ± 0.037
5.396ArgArg: 5.396 ± 0.06
3.367ArgSer: 3.367 ± 0.045
3.457ArgThr: 3.457 ± 0.042
5.478ArgVal: 5.478 ± 0.052
1.019ArgTrp: 1.019 ± 0.022
1.911ArgTyr: 1.911 ± 0.032
0.0ArgXaa: 0.0 ± 0.0
Ser
7.004SerAla: 7.004 ± 0.066
0.48SerCys: 0.48 ± 0.017
2.957SerAsp: 2.957 ± 0.037
2.555SerGlu: 2.555 ± 0.04
2.347SerPhe: 2.347 ± 0.03
5.302SerGly: 5.302 ± 0.057
1.264SerHis: 1.264 ± 0.024
2.948SerIle: 2.948 ± 0.038
1.734SerLys: 1.734 ± 0.03
5.64SerLeu: 5.64 ± 0.066
1.569SerMet: 1.569 ± 0.028
1.766SerAsn: 1.766 ± 0.031
2.755SerPro: 2.755 ± 0.04
1.794SerGln: 1.794 ± 0.035
3.691SerArg: 3.691 ± 0.044
3.438SerSer: 3.438 ± 0.052
3.107SerThr: 3.107 ± 0.04
4.383SerVal: 4.383 ± 0.047
0.695SerTrp: 0.695 ± 0.019
1.302SerTyr: 1.302 ± 0.028
0.0SerXaa: 0.0 ± 0.0
Thr
5.76ThrAla: 5.76 ± 0.054
0.432ThrCys: 0.432 ± 0.015
2.592ThrAsp: 2.592 ± 0.033
2.252ThrGlu: 2.252 ± 0.035
2.018ThrPhe: 2.018 ± 0.036
4.647ThrGly: 4.647 ± 0.051
1.352ThrHis: 1.352 ± 0.027
2.661ThrIle: 2.661 ± 0.036
1.436ThrLys: 1.436 ± 0.028
6.46ThrLeu: 6.46 ± 0.068
1.315ThrMet: 1.315 ± 0.021
1.453ThrAsn: 1.453 ± 0.03
3.465ThrPro: 3.465 ± 0.047
1.933ThrGln: 1.933 ± 0.032
3.674ThrArg: 3.674 ± 0.045
3.015ThrSer: 3.015 ± 0.041
2.877ThrThr: 2.877 ± 0.041
4.131ThrVal: 4.131 ± 0.048
0.643ThrTrp: 0.643 ± 0.017
1.27ThrTyr: 1.27 ± 0.027
0.0ThrXaa: 0.0 ± 0.0
Val
9.453ValAla: 9.453 ± 0.067
0.831ValCys: 0.831 ± 0.022
4.251ValAsp: 4.251 ± 0.046
4.093ValGlu: 4.093 ± 0.05
2.983ValPhe: 2.983 ± 0.046
5.374ValGly: 5.374 ± 0.062
1.529ValHis: 1.529 ± 0.028
3.971ValIle: 3.971 ± 0.045
2.476ValLys: 2.476 ± 0.043
7.772ValLeu: 7.772 ± 0.079
1.899ValMet: 1.899 ± 0.036
2.207ValAsn: 2.207 ± 0.041
3.943ValPro: 3.943 ± 0.05
2.408ValGln: 2.408 ± 0.038
5.188ValArg: 5.188 ± 0.055
4.598ValSer: 4.598 ± 0.05
4.489ValThr: 4.489 ± 0.049
6.035ValVal: 6.035 ± 0.064
0.959ValTrp: 0.959 ± 0.023
1.688ValTyr: 1.688 ± 0.028
0.0ValXaa: 0.0 ± 0.0
Trp
1.111TrpAla: 1.111 ± 0.024
0.135TrpCys: 0.135 ± 0.007
0.61TrpAsp: 0.61 ± 0.019
0.489TrpGlu: 0.489 ± 0.017
0.557TrpPhe: 0.557 ± 0.016
0.861TrpGly: 0.861 ± 0.021
0.389TrpHis: 0.389 ± 0.013
0.772TrpIle: 0.772 ± 0.018
0.429TrpLys: 0.429 ± 0.014
1.861TrpLeu: 1.861 ± 0.035
0.379TrpMet: 0.379 ± 0.014
0.463TrpAsn: 0.463 ± 0.016
0.641TrpPro: 0.641 ± 0.02
0.603TrpGln: 0.603 ± 0.017
1.235TrpArg: 1.235 ± 0.029
0.798TrpSer: 0.798 ± 0.021
0.729TrpThr: 0.729 ± 0.021
0.824TrpVal: 0.824 ± 0.021
0.208TrpTrp: 0.208 ± 0.01
0.3TrpTyr: 0.3 ± 0.013
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.867TyrAla: 2.867 ± 0.04
0.252TyrCys: 0.252 ± 0.011
1.344TyrAsp: 1.344 ± 0.028
1.22TyrGlu: 1.22 ± 0.026
1.057TyrPhe: 1.057 ± 0.024
2.206TyrGly: 2.206 ± 0.039
0.502TyrHis: 0.502 ± 0.015
0.937TyrIle: 0.937 ± 0.025
0.626TyrLys: 0.626 ± 0.02
2.442TyrLeu: 2.442 ± 0.033
0.493TyrMet: 0.493 ± 0.015
0.61TyrAsn: 0.61 ± 0.018
1.253TyrPro: 1.253 ± 0.024
0.796TyrGln: 0.796 ± 0.019
1.89TyrArg: 1.89 ± 0.034
1.276TyrSer: 1.276 ± 0.027
1.229TyrThr: 1.229 ± 0.027
1.842TyrVal: 1.842 ± 0.036
0.387TyrTrp: 0.387 ± 0.014
0.632TyrTyr: 0.632 ± 0.019
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.001
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6724 proteins (2040670 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski