Amino acid dipepetide frequency for Actinidia virus X

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.684AlaAla: 9.684 ± 3.207
0.842AlaCys: 0.842 ± 0.448
4.632AlaAsp: 4.632 ± 1.618
4.632AlaGlu: 4.632 ± 1.853
2.105AlaPhe: 2.105 ± 0.726
4.211AlaGly: 4.211 ± 1.489
2.947AlaHis: 2.947 ± 0.572
5.474AlaIle: 5.474 ± 2.836
4.211AlaLys: 4.211 ± 0.983
11.789AlaLeu: 11.789 ± 3.665
2.526AlaMet: 2.526 ± 0.866
4.632AlaAsn: 4.632 ± 1.133
5.474AlaPro: 5.474 ± 1.489
2.526AlaGln: 2.526 ± 0.618
3.789AlaArg: 3.789 ± 0.972
4.632AlaSer: 4.632 ± 1.175
6.737AlaThr: 6.737 ± 0.706
2.947AlaVal: 2.947 ± 1.494
0.0AlaTrp: 0.0 ± 0.0
5.474AlaTyr: 5.474 ± 1.022
0.0AlaXaa: 0.0 ± 0.0
Cys
1.263CysAla: 1.263 ± 1.192
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.842CysGlu: 0.842 ± 0.448
0.842CysPhe: 0.842 ± 0.448
2.105CysGly: 2.105 ± 1.284
0.842CysHis: 0.842 ± 0.667
0.842CysIle: 0.842 ± 0.64
1.263CysLys: 1.263 ± 0.672
0.421CysLeu: 0.421 ± 0.224
0.0CysMet: 0.0 ± 0.0
0.421CysAsn: 0.421 ± 0.224
2.947CysPro: 2.947 ± 1.62
0.842CysGln: 0.842 ± 0.667
0.842CysArg: 0.842 ± 0.729
2.526CysSer: 2.526 ± 1.146
1.263CysThr: 1.263 ± 0.708
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.368AspAla: 3.368 ± 1.263
0.421AspCys: 0.421 ± 0.786
2.105AspAsp: 2.105 ± 1.12
2.105AspGlu: 2.105 ± 0.726
3.368AspPhe: 3.368 ± 1.547
3.789AspGly: 3.789 ± 0.917
0.842AspHis: 0.842 ± 0.448
1.684AspIle: 1.684 ± 0.896
0.842AspLys: 0.842 ± 0.64
4.211AspLeu: 4.211 ± 1.689
0.842AspMet: 0.842 ± 0.448
1.684AspAsn: 1.684 ± 0.763
5.053AspPro: 5.053 ± 3.217
2.105AspGln: 2.105 ± 1.12
1.263AspArg: 1.263 ± 0.672
5.053AspSer: 5.053 ± 1.405
3.789AspThr: 3.789 ± 1.435
3.368AspVal: 3.368 ± 1.019
1.263AspTrp: 1.263 ± 0.672
2.105AspTyr: 2.105 ± 1.12
0.0AspXaa: 0.0 ± 0.0
Glu
6.316GluAla: 6.316 ± 2.132
0.421GluCys: 0.421 ± 0.224
3.368GluAsp: 3.368 ± 1.23
2.947GluGlu: 2.947 ± 1.119
2.105GluPhe: 2.105 ± 1.12
2.105GluGly: 2.105 ± 0.635
0.842GluHis: 0.842 ± 0.448
2.947GluIle: 2.947 ± 1.181
2.526GluLys: 2.526 ± 1.344
4.211GluLeu: 4.211 ± 1.689
0.842GluMet: 0.842 ± 0.448
2.526GluAsn: 2.526 ± 0.865
5.053GluPro: 5.053 ± 2.495
1.263GluGln: 1.263 ± 0.711
3.789GluArg: 3.789 ± 1.317
1.263GluSer: 1.263 ± 0.609
4.632GluThr: 4.632 ± 2.465
4.211GluVal: 4.211 ± 1.433
0.421GluTrp: 0.421 ± 0.224
1.684GluTyr: 1.684 ± 1.333
0.0GluXaa: 0.0 ± 0.0
Phe
2.526PheAla: 2.526 ± 1.248
2.105PheCys: 2.105 ± 0.635
2.526PheAsp: 2.526 ± 0.561
3.789PheGlu: 3.789 ± 0.949
1.684PhePhe: 1.684 ± 0.88
0.842PheGly: 0.842 ± 0.667
2.105PheHis: 2.105 ± 1.12
3.368PheIle: 3.368 ± 1.793
1.684PheLys: 1.684 ± 0.896
3.368PheLeu: 3.368 ± 2.307
1.263PheMet: 1.263 ± 0.672
1.263PheAsn: 1.263 ± 0.672
2.105PhePro: 2.105 ± 0.846
1.263PheGln: 1.263 ± 0.672
1.263PheArg: 1.263 ± 0.826
2.526PheSer: 2.526 ± 2.104
2.947PheThr: 2.947 ± 1.532
1.684PheVal: 1.684 ± 0.99
0.0PheTrp: 0.0 ± 0.0
1.263PheTyr: 1.263 ± 0.609
0.0PheXaa: 0.0 ± 0.0
Gly
2.526GlyAla: 2.526 ± 0.866
2.526GlyCys: 2.526 ± 2.376
4.632GlyAsp: 4.632 ± 1.65
0.842GlyGlu: 0.842 ± 0.738
1.684GlyPhe: 1.684 ± 0.769
2.947GlyGly: 2.947 ± 2.205
1.263GlyHis: 1.263 ± 0.711
2.947GlyIle: 2.947 ± 1.243
2.947GlyLys: 2.947 ± 0.818
4.211GlyLeu: 4.211 ± 2.601
0.842GlyMet: 0.842 ± 0.687
2.526GlyAsn: 2.526 ± 1.736
2.947GlyPro: 2.947 ± 1.243
1.263GlyGln: 1.263 ± 0.609
2.105GlyArg: 2.105 ± 1.44
4.211GlySer: 4.211 ± 1.616
3.789GlyThr: 3.789 ± 0.898
2.947GlyVal: 2.947 ± 0.816
0.421GlyTrp: 0.421 ± 0.224
1.263GlyTyr: 1.263 ± 0.609
0.0GlyXaa: 0.0 ± 0.0
His
3.789HisAla: 3.789 ± 1.517
0.842HisCys: 0.842 ± 0.729
0.0HisAsp: 0.0 ± 0.0
2.526HisGlu: 2.526 ± 0.869
2.105HisPhe: 2.105 ± 1.12
4.211HisGly: 4.211 ± 2.042
1.684HisHis: 1.684 ± 1.458
0.842HisIle: 0.842 ± 0.667
1.684HisLys: 1.684 ± 1.093
3.368HisLeu: 3.368 ± 1.793
0.421HisMet: 0.421 ± 0.224
0.421HisAsn: 0.421 ± 0.224
2.105HisPro: 2.105 ± 0.976
2.526HisGln: 2.526 ± 1.156
2.947HisArg: 2.947 ± 1.041
1.263HisSer: 1.263 ± 0.609
2.947HisThr: 2.947 ± 1.569
0.842HisVal: 0.842 ± 0.729
0.0HisTrp: 0.0 ± 0.0
0.842HisTyr: 0.842 ± 0.667
0.0HisXaa: 0.0 ± 0.0
Ile
5.053IleAla: 5.053 ± 2.059
0.0IleCys: 0.0 ± 0.0
2.526IleAsp: 2.526 ± 1.248
2.947IleGlu: 2.947 ± 1.042
2.526IlePhe: 2.526 ± 1.219
0.842IleGly: 0.842 ± 1.084
1.684IleHis: 1.684 ± 0.632
2.105IleIle: 2.105 ± 0.726
3.789IleLys: 3.789 ± 1.435
4.211IleLeu: 4.211 ± 1.643
0.842IleMet: 0.842 ± 0.448
2.526IleAsn: 2.526 ± 0.561
2.526IlePro: 2.526 ± 1.002
2.947IleGln: 2.947 ± 1.181
2.947IleArg: 2.947 ± 0.884
4.632IleSer: 4.632 ± 1.053
5.053IleThr: 5.053 ± 1.559
1.684IleVal: 1.684 ± 0.632
0.0IleTrp: 0.0 ± 0.0
2.105IleTyr: 2.105 ± 1.423
0.0IleXaa: 0.0 ± 0.0
Lys
2.947LysAla: 2.947 ± 1.042
0.421LysCys: 0.421 ± 0.224
2.105LysAsp: 2.105 ± 1.12
2.105LysGlu: 2.105 ± 1.12
2.105LysPhe: 2.105 ± 0.902
1.684LysGly: 1.684 ± 0.876
0.421LysHis: 0.421 ± 0.224
3.789LysIle: 3.789 ± 0.54
1.684LysLys: 1.684 ± 0.896
7.158LysLeu: 7.158 ± 1.938
2.105LysMet: 2.105 ± 0.717
2.105LysAsn: 2.105 ± 1.206
2.105LysPro: 2.105 ± 0.976
1.684LysGln: 1.684 ± 0.76
2.947LysArg: 2.947 ± 1.569
3.789LysSer: 3.789 ± 1.222
2.105LysThr: 2.105 ± 0.926
4.632LysVal: 4.632 ± 0.917
2.526LysTrp: 2.526 ± 1.081
0.421LysTyr: 0.421 ± 0.758
0.0LysXaa: 0.0 ± 0.0
Leu
5.474LeuAla: 5.474 ± 2.986
1.684LeuCys: 1.684 ± 0.876
5.474LeuAsp: 5.474 ± 1.86
7.158LeuGlu: 7.158 ± 1.823
5.474LeuPhe: 5.474 ± 2.134
5.053LeuGly: 5.053 ± 1.257
2.947LeuHis: 2.947 ± 0.659
4.211LeuIle: 4.211 ± 3.374
5.474LeuLys: 5.474 ± 2.46
10.105LeuLeu: 10.105 ± 4.762
1.684LeuMet: 1.684 ± 0.545
4.211LeuAsn: 4.211 ± 2.342
6.737LeuPro: 6.737 ± 2.33
4.211LeuGln: 4.211 ± 0.983
5.053LeuArg: 5.053 ± 2.356
5.474LeuSer: 5.474 ± 2.07
7.158LeuThr: 7.158 ± 1.958
4.211LeuVal: 4.211 ± 0.97
1.263LeuTrp: 1.263 ± 0.609
3.368LeuTyr: 3.368 ± 1.019
0.0LeuXaa: 0.0 ± 0.0
Met
2.947MetAla: 2.947 ± 1.274
0.421MetCys: 0.421 ± 0.758
0.421MetAsp: 0.421 ± 0.224
1.263MetGlu: 1.263 ± 0.609
0.0MetPhe: 0.0 ± 0.0
2.105MetGly: 2.105 ± 1.206
1.263MetHis: 1.263 ± 0.672
0.421MetIle: 0.421 ± 0.224
0.421MetLys: 0.421 ± 0.224
2.526MetLeu: 2.526 ± 1.344
0.0MetMet: 0.0 ± 0.0
0.421MetAsn: 0.421 ± 0.224
0.842MetPro: 0.842 ± 1.317
1.263MetGln: 1.263 ± 0.672
2.947MetArg: 2.947 ± 1.042
0.842MetSer: 0.842 ± 0.835
1.263MetThr: 1.263 ± 0.586
0.842MetVal: 0.842 ± 0.448
0.421MetTrp: 0.421 ± 0.758
0.421MetTyr: 0.421 ± 0.758
0.0MetXaa: 0.0 ± 0.0
Asn
4.211AsnAla: 4.211 ± 1.84
1.684AsnCys: 1.684 ± 0.896
1.684AsnAsp: 1.684 ± 0.763
0.842AsnGlu: 0.842 ± 0.64
1.263AsnPhe: 1.263 ± 0.711
1.263AsnGly: 1.263 ± 1.017
2.526AsnHis: 2.526 ± 1.423
2.526AsnIle: 2.526 ± 0.865
1.684AsnLys: 1.684 ± 0.632
4.211AsnLeu: 4.211 ± 1.314
0.842AsnMet: 0.842 ± 1.143
2.526AsnAsn: 2.526 ± 0.869
2.947AsnPro: 2.947 ± 1.398
0.421AsnGln: 0.421 ± 0.224
2.105AsnArg: 2.105 ± 0.87
0.842AsnSer: 0.842 ± 0.448
2.526AsnThr: 2.526 ± 0.561
2.947AsnVal: 2.947 ± 1.181
0.421AsnTrp: 0.421 ± 0.758
2.526AsnTyr: 2.526 ± 0.561
0.0AsnXaa: 0.0 ± 0.0
Pro
8.421ProAla: 8.421 ± 1.748
1.263ProCys: 1.263 ± 0.826
6.316ProAsp: 6.316 ± 1.436
6.737ProGlu: 6.737 ± 3.209
0.842ProPhe: 0.842 ± 0.738
2.526ProGly: 2.526 ± 1.028
2.947ProHis: 2.947 ± 1.245
3.789ProIle: 3.789 ± 1.073
4.211ProLys: 4.211 ± 0.983
5.474ProLeu: 5.474 ± 2.023
0.421ProMet: 0.421 ± 0.224
0.421ProAsn: 0.421 ± 0.224
6.316ProPro: 6.316 ± 2.41
2.526ProGln: 2.526 ± 2.317
0.842ProArg: 0.842 ± 1.181
4.211ProSer: 4.211 ± 1.734
8.842ProThr: 8.842 ± 3.083
4.632ProVal: 4.632 ± 1.127
1.263ProTrp: 1.263 ± 1.252
2.105ProTyr: 2.105 ± 0.726
0.0ProXaa: 0.0 ± 0.0
Gln
2.947GlnAla: 2.947 ± 1.743
0.0GlnCys: 0.0 ± 0.0
1.263GlnAsp: 1.263 ± 0.672
3.368GlnGlu: 3.368 ± 1.234
0.842GlnPhe: 0.842 ± 0.64
1.263GlnGly: 1.263 ± 0.586
0.842GlnHis: 0.842 ± 0.448
2.105GlnIle: 2.105 ± 0.87
3.368GlnLys: 3.368 ± 0.596
6.316GlnLeu: 6.316 ± 1.592
1.263GlnMet: 1.263 ± 0.672
1.263GlnAsn: 1.263 ± 0.586
4.632GlnPro: 4.632 ± 1.146
1.263GlnGln: 1.263 ± 0.708
0.842GlnArg: 0.842 ± 0.835
4.211GlnSer: 4.211 ± 1.489
2.105GlnThr: 2.105 ± 1.12
3.368GlnVal: 3.368 ± 1.344
0.421GlnTrp: 0.421 ± 0.224
0.421GlnTyr: 0.421 ± 0.786
0.0GlnXaa: 0.0 ± 0.0
Arg
5.053ArgAla: 5.053 ± 0.714
0.0ArgCys: 0.0 ± 0.0
2.947ArgAsp: 2.947 ± 1.187
1.684ArgGlu: 1.684 ± 0.615
3.368ArgPhe: 3.368 ± 1.748
1.263ArgGly: 1.263 ± 1.385
1.263ArgHis: 1.263 ± 0.909
1.263ArgIle: 1.263 ± 0.672
0.421ArgLys: 0.421 ± 0.224
3.368ArgLeu: 3.368 ± 1.734
1.263ArgMet: 1.263 ± 0.966
2.947ArgAsn: 2.947 ± 1.041
3.368ArgPro: 3.368 ± 1.775
7.158ArgGln: 7.158 ± 3.492
2.947ArgArg: 2.947 ± 1.033
3.368ArgSer: 3.368 ± 2.194
4.211ArgThr: 4.211 ± 2.241
2.105ArgVal: 2.105 ± 1.348
0.0ArgTrp: 0.0 ± 0.0
2.526ArgTyr: 2.526 ± 1.344
0.0ArgXaa: 0.0 ± 0.0
Ser
5.474SerAla: 5.474 ± 1.685
0.842SerCys: 0.842 ± 0.667
3.368SerAsp: 3.368 ± 0.663
2.105SerGlu: 2.105 ± 1.12
1.684SerPhe: 1.684 ± 1.333
4.211SerGly: 4.211 ± 2.106
3.789SerHis: 3.789 ± 1.733
2.947SerIle: 2.947 ± 0.659
4.632SerLys: 4.632 ± 1.832
5.895SerLeu: 5.895 ± 3.14
0.842SerMet: 0.842 ± 0.448
2.947SerAsn: 2.947 ± 1.181
5.474SerPro: 5.474 ± 1.373
3.368SerGln: 3.368 ± 1.063
2.947SerArg: 2.947 ± 0.72
3.368SerSer: 3.368 ± 2.31
3.789SerThr: 3.789 ± 1.429
4.211SerVal: 4.211 ± 1.14
0.421SerTrp: 0.421 ± 0.224
2.105SerTyr: 2.105 ± 0.755
0.0SerXaa: 0.0 ± 0.0
Thr
4.211ThrAla: 4.211 ± 1.015
2.105ThrCys: 2.105 ± 1.522
2.105ThrAsp: 2.105 ± 1.206
2.526ThrGlu: 2.526 ± 0.869
4.211ThrPhe: 4.211 ± 1.635
2.947ThrGly: 2.947 ± 1.154
4.632ThrHis: 4.632 ± 1.014
4.632ThrIle: 4.632 ± 0.735
2.947ThrLys: 2.947 ± 0.937
8.0ThrLeu: 8.0 ± 3.481
2.947ThrMet: 2.947 ± 1.109
1.684ThrAsn: 1.684 ± 1.501
7.158ThrPro: 7.158 ± 2.812
1.684ThrGln: 1.684 ± 0.896
3.789ThrArg: 3.789 ± 1.709
6.737ThrSer: 6.737 ± 2.421
6.316ThrThr: 6.316 ± 2.331
4.632ThrVal: 4.632 ± 1.519
0.421ThrTrp: 0.421 ± 0.224
2.105ThrTyr: 2.105 ± 0.87
0.0ThrXaa: 0.0 ± 0.0
Val
4.632ValAla: 4.632 ± 1.829
0.421ValCys: 0.421 ± 0.81
2.105ValAsp: 2.105 ± 1.642
2.947ValGlu: 2.947 ± 1.569
1.684ValPhe: 1.684 ± 0.747
4.211ValGly: 4.211 ± 1.41
1.263ValHis: 1.263 ± 0.711
2.526ValIle: 2.526 ± 2.0
3.368ValLys: 3.368 ± 1.171
4.211ValLeu: 4.211 ± 1.76
0.842ValMet: 0.842 ± 0.448
2.947ValAsn: 2.947 ± 1.042
3.789ValPro: 3.789 ± 1.532
3.368ValGln: 3.368 ± 1.234
4.632ValArg: 4.632 ± 1.181
1.684ValSer: 1.684 ± 2.254
4.211ValThr: 4.211 ± 1.568
5.053ValVal: 5.053 ± 0.872
1.263ValTrp: 1.263 ± 1.113
2.526ValTyr: 2.526 ± 1.354
0.0ValXaa: 0.0 ± 0.0
Trp
1.263TrpAla: 1.263 ± 0.672
0.0TrpCys: 0.0 ± 0.0
0.421TrpAsp: 0.421 ± 0.758
1.263TrpGlu: 1.263 ± 0.672
0.0TrpPhe: 0.0 ± 0.0
0.421TrpGly: 0.421 ± 0.786
0.421TrpHis: 0.421 ± 0.224
0.0TrpIle: 0.0 ± 0.0
0.842TrpLys: 0.842 ± 0.729
0.842TrpLeu: 0.842 ± 0.448
0.421TrpMet: 0.421 ± 0.224
1.263TrpAsn: 1.263 ± 1.017
0.842TrpPro: 0.842 ± 0.835
0.421TrpGln: 0.421 ± 0.224
0.421TrpArg: 0.421 ± 0.224
0.0TrpSer: 0.0 ± 0.0
0.421TrpThr: 0.421 ± 0.81
2.105TrpVal: 2.105 ± 0.755
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
7.158TyrAla: 7.158 ± 1.441
1.263TyrCys: 1.263 ± 0.711
1.263TyrAsp: 1.263 ± 0.609
0.842TyrGlu: 0.842 ± 0.64
1.684TyrPhe: 1.684 ± 0.615
0.842TyrGly: 0.842 ± 0.667
0.842TyrHis: 0.842 ± 0.448
2.526TyrIle: 2.526 ± 0.866
0.842TyrLys: 0.842 ± 0.448
2.947TyrLeu: 2.947 ± 1.221
0.421TyrMet: 0.421 ± 0.224
1.263TyrAsn: 1.263 ± 0.711
1.684TyrPro: 1.684 ± 0.632
0.0TyrGln: 0.0 ± 0.0
2.105TyrArg: 2.105 ± 1.981
3.789TyrSer: 3.789 ± 2.017
1.684TyrThr: 1.684 ± 0.632
1.263TyrVal: 1.263 ± 0.938
0.842TyrTrp: 0.842 ± 0.448
0.421TyrTyr: 0.421 ± 0.224
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2376 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski