Amino acid dipepetide frequency for Fusarium poae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.058AlaAla: 8.058 ± 0.064
1.073AlaCys: 1.073 ± 0.013
4.084AlaAsp: 4.084 ± 0.027
4.992AlaGlu: 4.992 ± 0.047
3.07AlaPhe: 3.07 ± 0.023
5.205AlaGly: 5.205 ± 0.037
1.718AlaHis: 1.718 ± 0.016
4.417AlaIle: 4.417 ± 0.028
4.273AlaLys: 4.273 ± 0.037
7.251AlaLeu: 7.251 ± 0.037
1.934AlaMet: 1.934 ± 0.017
2.868AlaAsn: 2.868 ± 0.022
4.421AlaPro: 4.421 ± 0.042
3.25AlaGln: 3.25 ± 0.026
4.553AlaArg: 4.553 ± 0.032
6.817AlaSer: 6.817 ± 0.04
5.059AlaThr: 5.059 ± 0.034
5.076AlaVal: 5.076 ± 0.029
1.157AlaTrp: 1.157 ± 0.013
2.117AlaTyr: 2.117 ± 0.018
0.0AlaXaa: 0.0 ± 0.0
Cys
0.911CysAla: 0.911 ± 0.013
0.268CysCys: 0.268 ± 0.006
0.755CysAsp: 0.755 ± 0.011
0.683CysGlu: 0.683 ± 0.012
0.594CysPhe: 0.594 ± 0.009
0.953CysGly: 0.953 ± 0.015
0.368CysHis: 0.368 ± 0.008
0.781CysIle: 0.781 ± 0.013
0.609CysLys: 0.609 ± 0.011
1.287CysLeu: 1.287 ± 0.016
0.287CysMet: 0.287 ± 0.006
0.492CysAsn: 0.492 ± 0.008
0.69CysPro: 0.69 ± 0.011
0.526CysGln: 0.526 ± 0.009
0.799CysArg: 0.799 ± 0.013
0.923CysSer: 0.923 ± 0.012
0.738CysThr: 0.738 ± 0.014
0.8CysVal: 0.8 ± 0.014
0.23CysTrp: 0.23 ± 0.006
0.379CysTyr: 0.379 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
4.673AspAla: 4.673 ± 0.03
0.711AspCys: 0.711 ± 0.011
4.665AspAsp: 4.665 ± 0.037
4.817AspGlu: 4.817 ± 0.035
2.301AspPhe: 2.301 ± 0.021
4.153AspGly: 4.153 ± 0.031
1.338AspHis: 1.338 ± 0.014
3.385AspIle: 3.385 ± 0.024
2.874AspLys: 2.874 ± 0.025
5.104AspLeu: 5.104 ± 0.031
1.382AspMet: 1.382 ± 0.015
2.275AspAsn: 2.275 ± 0.022
3.281AspPro: 3.281 ± 0.02
2.038AspGln: 2.038 ± 0.017
3.087AspArg: 3.087 ± 0.03
4.279AspSer: 4.279 ± 0.028
3.209AspThr: 3.209 ± 0.026
3.752AspVal: 3.752 ± 0.026
1.046AspTrp: 1.046 ± 0.012
1.659AspTyr: 1.659 ± 0.015
0.0AspXaa: 0.0 ± 0.0
Glu
5.541GluAla: 5.541 ± 0.043
0.726GluCys: 0.726 ± 0.011
4.377GluAsp: 4.377 ± 0.03
5.59GluGlu: 5.59 ± 0.054
2.026GluPhe: 2.026 ± 0.016
3.691GluGly: 3.691 ± 0.025
1.511GluHis: 1.511 ± 0.015
3.107GluIle: 3.107 ± 0.024
3.776GluLys: 3.776 ± 0.035
5.122GluLeu: 5.122 ± 0.033
1.471GluMet: 1.471 ± 0.016
2.437GluAsn: 2.437 ± 0.019
2.973GluPro: 2.973 ± 0.04
2.576GluGln: 2.576 ± 0.023
3.973GluArg: 3.973 ± 0.033
4.405GluSer: 4.405 ± 0.03
3.798GluThr: 3.798 ± 0.026
3.58GluVal: 3.58 ± 0.026
1.016GluTrp: 1.016 ± 0.012
1.771GluTyr: 1.771 ± 0.018
0.0GluXaa: 0.0 ± 0.0
Phe
2.841PheAla: 2.841 ± 0.023
0.583PheCys: 0.583 ± 0.009
2.376PheAsp: 2.376 ± 0.019
2.267PheGlu: 2.267 ± 0.019
1.607PhePhe: 1.607 ± 0.019
2.778PheGly: 2.778 ± 0.022
0.918PheHis: 0.918 ± 0.011
1.962PheIle: 1.962 ± 0.02
1.677PheLys: 1.677 ± 0.018
3.406PheLeu: 3.406 ± 0.024
0.847PheMet: 0.847 ± 0.012
1.546PheAsn: 1.546 ± 0.017
1.83PhePro: 1.83 ± 0.016
1.435PheGln: 1.435 ± 0.015
1.974PheArg: 1.974 ± 0.017
2.96PheSer: 2.96 ± 0.022
2.169PheThr: 2.169 ± 0.015
2.305PheVal: 2.305 ± 0.023
0.67PheTrp: 0.67 ± 0.011
1.092PheTyr: 1.092 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
4.781GlyAla: 4.781 ± 0.034
0.882GlyCys: 0.882 ± 0.013
3.686GlyAsp: 3.686 ± 0.028
3.481GlyGlu: 3.481 ± 0.024
2.759GlyPhe: 2.759 ± 0.022
5.159GlyGly: 5.159 ± 0.049
1.769GlyHis: 1.769 ± 0.023
3.609GlyIle: 3.609 ± 0.026
3.484GlyLys: 3.484 ± 0.029
5.84GlyLeu: 5.84 ± 0.037
1.555GlyMet: 1.555 ± 0.017
2.649GlyAsn: 2.649 ± 0.021
3.092GlyPro: 3.092 ± 0.027
2.613GlyGln: 2.613 ± 0.022
4.047GlyArg: 4.047 ± 0.03
5.456GlySer: 5.456 ± 0.035
3.791GlyThr: 3.791 ± 0.039
4.074GlyVal: 4.074 ± 0.025
1.227GlyTrp: 1.227 ± 0.013
2.099GlyTyr: 2.099 ± 0.021
0.0GlyXaa: 0.0 ± 0.0
His
1.698HisAla: 1.698 ± 0.015
0.366HisCys: 0.366 ± 0.007
1.494HisAsp: 1.494 ± 0.015
1.448HisGlu: 1.448 ± 0.02
0.969HisPhe: 0.969 ± 0.012
1.77HisGly: 1.77 ± 0.015
0.871HisHis: 0.871 ± 0.015
1.329HisIle: 1.329 ± 0.015
1.071HisLys: 1.071 ± 0.015
2.224HisLeu: 2.224 ± 0.018
0.521HisMet: 0.521 ± 0.009
0.955HisAsn: 0.955 ± 0.012
1.612HisPro: 1.612 ± 0.015
1.065HisGln: 1.065 ± 0.014
1.525HisArg: 1.525 ± 0.015
1.773HisSer: 1.773 ± 0.015
1.249HisThr: 1.249 ± 0.015
1.417HisVal: 1.417 ± 0.015
0.371HisTrp: 0.371 ± 0.007
0.731HisTyr: 0.731 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
4.198IleAla: 4.198 ± 0.024
0.799IleCys: 0.799 ± 0.012
3.131IleAsp: 3.131 ± 0.019
3.141IleGlu: 3.141 ± 0.02
1.977IlePhe: 1.977 ± 0.021
3.242IleGly: 3.242 ± 0.026
1.259IleHis: 1.259 ± 0.013
2.757IleIle: 2.757 ± 0.023
2.484IleLys: 2.484 ± 0.021
4.606IleLeu: 4.606 ± 0.03
1.095IleMet: 1.095 ± 0.013
1.985IleAsn: 1.985 ± 0.016
3.037IlePro: 3.037 ± 0.024
2.044IleGln: 2.044 ± 0.017
2.961IleArg: 2.961 ± 0.022
3.914IleSer: 3.914 ± 0.027
2.952IleThr: 2.952 ± 0.031
3.235IleVal: 3.235 ± 0.025
0.839IleTrp: 0.839 ± 0.014
1.431IleTyr: 1.431 ± 0.015
0.0IleXaa: 0.0 ± 0.0
Lys
4.398LysAla: 4.398 ± 0.031
0.585LysCys: 0.585 ± 0.011
3.185LysAsp: 3.185 ± 0.034
3.529LysGlu: 3.529 ± 0.03
1.541LysPhe: 1.541 ± 0.016
3.127LysGly: 3.127 ± 0.027
1.234LysHis: 1.234 ± 0.014
2.394LysIle: 2.394 ± 0.019
3.607LysLys: 3.607 ± 0.035
4.273LysLeu: 4.273 ± 0.028
1.121LysMet: 1.121 ± 0.016
1.955LysAsn: 1.955 ± 0.018
2.932LysPro: 2.932 ± 0.031
2.044LysGln: 2.044 ± 0.019
3.57LysArg: 3.57 ± 0.027
3.691LysSer: 3.691 ± 0.026
3.154LysThr: 3.154 ± 0.022
2.922LysVal: 2.922 ± 0.023
0.762LysTrp: 0.762 ± 0.012
1.439LysTyr: 1.439 ± 0.016
0.0LysXaa: 0.0 ± 0.0
Leu
7.248LeuAla: 7.248 ± 0.043
1.214LeuCys: 1.214 ± 0.016
5.425LeuAsp: 5.425 ± 0.032
5.565LeuGlu: 5.565 ± 0.035
3.241LeuPhe: 3.241 ± 0.029
5.609LeuGly: 5.609 ± 0.036
2.18LeuHis: 2.18 ± 0.019
3.946LeuIle: 3.946 ± 0.026
4.353LeuLys: 4.353 ± 0.027
7.954LeuLeu: 7.954 ± 0.054
1.77LeuMet: 1.77 ± 0.017
3.141LeuAsn: 3.141 ± 0.023
5.226LeuPro: 5.226 ± 0.034
3.777LeuGln: 3.777 ± 0.026
5.671LeuArg: 5.671 ± 0.036
7.04LeuSer: 7.04 ± 0.039
4.698LeuThr: 4.698 ± 0.028
5.254LeuVal: 5.254 ± 0.031
1.255LeuTrp: 1.255 ± 0.016
2.284LeuTyr: 2.284 ± 0.02
0.0LeuXaa: 0.0 ± 0.0
Met
2.256MetAla: 2.256 ± 0.018
0.249MetCys: 0.249 ± 0.006
1.364MetAsp: 1.364 ± 0.014
1.335MetGlu: 1.335 ± 0.015
0.755MetPhe: 0.755 ± 0.011
1.468MetGly: 1.468 ± 0.017
0.478MetHis: 0.478 ± 0.009
1.058MetIle: 1.058 ± 0.013
1.062MetLys: 1.062 ± 0.012
1.837MetLeu: 1.837 ± 0.021
0.63MetMet: 0.63 ± 0.01
0.827MetAsn: 0.827 ± 0.012
1.307MetPro: 1.307 ± 0.016
0.817MetGln: 0.817 ± 0.011
1.224MetArg: 1.224 ± 0.014
1.984MetSer: 1.984 ± 0.017
1.384MetThr: 1.384 ± 0.016
1.339MetVal: 1.339 ± 0.015
0.284MetTrp: 0.284 ± 0.007
0.528MetTyr: 0.528 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
3.048AsnAla: 3.048 ± 0.022
0.485AsnCys: 0.485 ± 0.009
2.252AsnAsp: 2.252 ± 0.018
2.162AsnGlu: 2.162 ± 0.019
1.421AsnPhe: 1.421 ± 0.015
3.029AsnGly: 3.029 ± 0.028
0.923AsnHis: 0.923 ± 0.013
2.182AsnIle: 2.182 ± 0.02
1.884AsnLys: 1.884 ± 0.019
3.282AsnLeu: 3.282 ± 0.027
0.917AsnMet: 0.917 ± 0.013
1.692AsnAsn: 1.692 ± 0.019
2.433AsnPro: 2.433 ± 0.022
1.44AsnGln: 1.44 ± 0.018
2.102AsnArg: 2.102 ± 0.019
2.822AsnSer: 2.822 ± 0.024
2.318AsnThr: 2.318 ± 0.02
2.295AsnVal: 2.295 ± 0.018
0.636AsnTrp: 0.636 ± 0.01
1.064AsnTyr: 1.064 ± 0.013
0.0AsnXaa: 0.0 ± 0.0
Pro
4.777ProAla: 4.777 ± 0.04
0.567ProCys: 0.567 ± 0.01
3.302ProAsp: 3.302 ± 0.025
3.98ProGlu: 3.98 ± 0.031
2.018ProPhe: 2.018 ± 0.018
3.793ProGly: 3.793 ± 0.043
1.266ProHis: 1.266 ± 0.015
2.542ProIle: 2.542 ± 0.021
2.804ProLys: 2.804 ± 0.03
4.461ProLeu: 4.461 ± 0.033
1.109ProMet: 1.109 ± 0.014
2.206ProAsn: 2.206 ± 0.019
4.667ProPro: 4.667 ± 0.058
2.428ProGln: 2.428 ± 0.025
3.276ProArg: 3.276 ± 0.028
5.61ProSer: 5.61 ± 0.041
3.838ProThr: 3.838 ± 0.034
3.48ProVal: 3.48 ± 0.028
0.762ProTrp: 0.762 ± 0.011
1.457ProTyr: 1.457 ± 0.017
0.0ProXaa: 0.0 ± 0.0
Gln
3.417GlnAla: 3.417 ± 0.027
0.472GlnCys: 0.472 ± 0.009
2.328GlnAsp: 2.328 ± 0.019
2.6GlnGlu: 2.6 ± 0.023
1.279GlnPhe: 1.279 ± 0.013
2.479GlnGly: 2.479 ± 0.021
1.133GlnHis: 1.133 ± 0.013
1.932GlnIle: 1.932 ± 0.019
2.05GlnLys: 2.05 ± 0.017
3.442GlnLeu: 3.442 ± 0.027
0.88GlnMet: 0.88 ± 0.012
1.614GlnAsn: 1.614 ± 0.02
2.582GlnPro: 2.582 ± 0.031
2.519GlnGln: 2.519 ± 0.047
2.753GlnArg: 2.753 ± 0.027
3.076GlnSer: 3.076 ± 0.025
2.384GlnThr: 2.384 ± 0.024
2.278GlnVal: 2.278 ± 0.019
0.665GlnTrp: 0.665 ± 0.01
1.203GlnTyr: 1.203 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
4.443ArgAla: 4.443 ± 0.029
0.809ArgCys: 0.809 ± 0.011
3.561ArgAsp: 3.561 ± 0.028
3.784ArgGlu: 3.784 ± 0.032
2.175ArgPhe: 2.175 ± 0.018
3.527ArgGly: 3.527 ± 0.027
1.658ArgHis: 1.658 ± 0.017
2.946ArgIle: 2.946 ± 0.024
3.481ArgLys: 3.481 ± 0.025
5.463ArgLeu: 5.463 ± 0.033
1.318ArgMet: 1.318 ± 0.014
2.377ArgAsn: 2.377 ± 0.021
3.437ArgPro: 3.437 ± 0.028
2.754ArgGln: 2.754 ± 0.026
5.094ArgArg: 5.094 ± 0.035
4.682ArgSer: 4.682 ± 0.034
3.246ArgThr: 3.246 ± 0.023
3.283ArgVal: 3.283 ± 0.022
1.021ArgTrp: 1.021 ± 0.015
1.732ArgTyr: 1.732 ± 0.018
0.0ArgXaa: 0.0 ± 0.0
Ser
6.052SerAla: 6.052 ± 0.039
0.917SerCys: 0.917 ± 0.013
4.442SerAsp: 4.442 ± 0.03
4.278SerGlu: 4.278 ± 0.03
3.055SerPhe: 3.055 ± 0.026
5.229SerGly: 5.229 ± 0.032
1.99SerHis: 1.99 ± 0.017
4.105SerIle: 4.105 ± 0.028
3.867SerLys: 3.867 ± 0.026
6.887SerLeu: 6.887 ± 0.038
1.74SerMet: 1.74 ± 0.017
3.051SerAsn: 3.051 ± 0.023
5.111SerPro: 5.111 ± 0.039
3.436SerGln: 3.436 ± 0.028
4.964SerArg: 4.964 ± 0.033
8.156SerSer: 8.156 ± 0.062
5.366SerThr: 5.366 ± 0.042
4.445SerVal: 4.445 ± 0.029
1.238SerTrp: 1.238 ± 0.016
2.081SerTyr: 2.081 ± 0.019
0.0SerXaa: 0.0 ± 0.0
Thr
4.926ThrAla: 4.926 ± 0.033
0.819ThrCys: 0.819 ± 0.011
3.055ThrAsp: 3.055 ± 0.023
3.366ThrGlu: 3.366 ± 0.028
2.218ThrPhe: 2.218 ± 0.018
4.087ThrGly: 4.087 ± 0.037
1.275ThrHis: 1.275 ± 0.013
3.251ThrIle: 3.251 ± 0.034
2.9ThrLys: 2.9 ± 0.025
5.097ThrLeu: 5.097 ± 0.029
1.241ThrMet: 1.241 ± 0.013
2.149ThrAsn: 2.149 ± 0.02
4.201ThrPro: 4.201 ± 0.038
2.203ThrGln: 2.203 ± 0.02
3.263ThrArg: 3.263 ± 0.025
5.212ThrSer: 5.212 ± 0.041
4.421ThrThr: 4.421 ± 0.066
3.762ThrVal: 3.762 ± 0.045
0.919ThrTrp: 0.919 ± 0.013
1.605ThrTyr: 1.605 ± 0.017
0.0ThrXaa: 0.0 ± 0.0
Val
4.91ValAla: 4.91 ± 0.028
0.858ValCys: 0.858 ± 0.013
3.826ValAsp: 3.826 ± 0.028
3.902ValGlu: 3.902 ± 0.027
2.428ValPhe: 2.428 ± 0.021
3.779ValGly: 3.779 ± 0.026
1.371ValHis: 1.371 ± 0.013
3.067ValIle: 3.067 ± 0.022
3.076ValLys: 3.076 ± 0.029
5.286ValLeu: 5.286 ± 0.033
1.324ValMet: 1.324 ± 0.014
2.28ValAsn: 2.28 ± 0.019
3.408ValPro: 3.408 ± 0.026
2.357ValGln: 2.357 ± 0.019
3.267ValArg: 3.267 ± 0.024
4.55ValSer: 4.55 ± 0.029
3.573ValThr: 3.573 ± 0.036
4.174ValVal: 4.174 ± 0.029
0.892ValTrp: 0.892 ± 0.012
1.724ValTyr: 1.724 ± 0.017
0.0ValXaa: 0.0 ± 0.0
Trp
1.174TrpAla: 1.174 ± 0.016
0.21TrpCys: 0.21 ± 0.006
0.989TrpAsp: 0.989 ± 0.014
0.91TrpGlu: 0.91 ± 0.012
0.613TrpPhe: 0.613 ± 0.009
0.924TrpGly: 0.924 ± 0.013
0.396TrpHis: 0.396 ± 0.008
0.909TrpIle: 0.909 ± 0.013
0.898TrpLys: 0.898 ± 0.012
1.476TrpLeu: 1.476 ± 0.016
0.404TrpMet: 0.404 ± 0.009
0.699TrpAsn: 0.699 ± 0.011
0.658TrpPro: 0.658 ± 0.011
0.631TrpGln: 0.631 ± 0.011
0.984TrpArg: 0.984 ± 0.012
1.1TrpSer: 1.1 ± 0.012
1.011TrpThr: 1.011 ± 0.012
0.997TrpVal: 0.997 ± 0.012
0.303TrpTrp: 0.303 ± 0.007
0.493TrpTyr: 0.493 ± 0.008
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.044TyrAla: 2.044 ± 0.017
0.478TyrCys: 0.478 ± 0.009
1.733TyrAsp: 1.733 ± 0.017
1.64TyrGlu: 1.64 ± 0.016
1.198TyrPhe: 1.198 ± 0.014
2.049TyrGly: 2.049 ± 0.019
0.802TyrHis: 0.802 ± 0.011
1.41TyrIle: 1.41 ± 0.016
1.234TyrLys: 1.234 ± 0.015
2.551TyrLeu: 2.551 ± 0.021
0.641TyrMet: 0.641 ± 0.01
1.189TyrAsn: 1.189 ± 0.016
1.444TyrPro: 1.444 ± 0.017
1.132TyrGln: 1.132 ± 0.014
1.703TyrArg: 1.703 ± 0.016
1.96TyrSer: 1.96 ± 0.017
1.611TyrThr: 1.611 ± 0.018
1.585TyrVal: 1.585 ± 0.016
0.484TyrTrp: 0.484 ± 0.008
0.982TyrTyr: 0.982 ± 0.013
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 14048 proteins (7061983 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski