Amino acid dipepetide frequency for Enhygromyxa salina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.123AlaAla: 16.123 ± 0.141	1.852AlaCys: 1.852 ± 0.034	6.873AlaAsp: 6.873 ± 0.054	8.859AlaGlu: 8.859 ± 0.081	3.209AlaPhe: 3.209 ± 0.04	10.201AlaGly: 10.201 ± 0.064	2.525AlaHis: 2.525 ± 0.032	4.661AlaIle: 4.661 ± 0.05	3.559AlaLys: 3.559 ± 0.056	14.105AlaLeu: 14.105 ± 0.144	2.28AlaMet: 2.28 ± 0.03	2.372AlaAsn: 2.372 ± 0.037	6.498AlaPro: 6.498 ± 0.059	3.827AlaGln: 3.827 ± 0.047	10.586AlaArg: 10.586 ± 0.109	6.928AlaSer: 6.928 ± 0.057	5.647AlaThr: 5.647 ± 0.047	8.091AlaVal: 8.091 ± 0.073	1.972AlaTrp: 1.972 ± 0.035	2.183AlaTyr: 2.183 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	1.478CysAla: 1.478 ± 0.032	0.193CysCys: 0.193 ± 0.009	1.046CysAsp: 1.046 ± 0.03	0.977CysGlu: 0.977 ± 0.023	0.373CysPhe: 0.373 ± 0.013	1.287CysGly: 1.287 ± 0.028	0.314CysHis: 0.314 ± 0.014	0.352CysIle: 0.352 ± 0.012	0.293CysLys: 0.293 ± 0.011	1.005CysLeu: 1.005 ± 0.022	0.24CysMet: 0.24 ± 0.009	0.288CysAsn: 0.288 ± 0.014	0.706CysPro: 0.706 ± 0.02	0.34CysGln: 0.34 ± 0.014	0.76CysArg: 0.76 ± 0.017	0.806CysSer: 0.806 ± 0.02	0.692CysThr: 0.692 ± 0.021	1.107CysVal: 1.107 ± 0.022	0.23CysTrp: 0.23 ± 0.016	0.248CysTyr: 0.248 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.972AspAla: 7.972 ± 0.072	0.805AspCys: 0.805 ± 0.026	5.155AspAsp: 5.155 ± 0.076	5.591AspGlu: 5.591 ± 0.075	1.972AspPhe: 1.972 ± 0.029	7.971AspGly: 7.971 ± 0.138	1.531AspHis: 1.531 ± 0.026	2.092AspIle: 2.092 ± 0.032	1.429AspLys: 1.429 ± 0.032	6.109AspLeu: 6.109 ± 0.061	1.033AspMet: 1.033 ± 0.02	1.377AspAsn: 1.377 ± 0.026	5.362AspPro: 5.362 ± 0.058	2.1AspGln: 2.1 ± 0.033	4.539AspArg: 4.539 ± 0.045	2.994AspSer: 2.994 ± 0.041	2.832AspThr: 2.832 ± 0.044	3.762AspVal: 3.762 ± 0.041	0.92AspTrp: 0.92 ± 0.02	1.385AspTyr: 1.385 ± 0.025	0.0AspXaa: 0.0 ± 0.0
Glu	9.15GluAla: 9.15 ± 0.082	0.674GluCys: 0.674 ± 0.022	3.82GluAsp: 3.82 ± 0.06	2.972GluGlu: 2.972 ± 0.054	2.049GluPhe: 2.049 ± 0.031	5.739GluGly: 5.739 ± 0.051	1.837GluHis: 1.837 ± 0.028	3.065GluIle: 3.065 ± 0.04	1.072GluLys: 1.072 ± 0.028	11.15GluLeu: 11.15 ± 0.098	0.963GluMet: 0.963 ± 0.024	0.984GluAsn: 0.984 ± 0.023	4.697GluPro: 4.697 ± 0.056	3.086GluGln: 3.086 ± 0.041	6.801GluArg: 6.801 ± 0.078	2.895GluSer: 2.895 ± 0.034	3.244GluThr: 3.244 ± 0.045	5.482GluVal: 5.482 ± 0.052	0.786GluTrp: 0.786 ± 0.018	1.139GluTyr: 1.139 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	3.775PheAla: 3.775 ± 0.038	0.425PheCys: 0.425 ± 0.014	2.498PheAsp: 2.498 ± 0.029	2.7PheGlu: 2.7 ± 0.032	1.039PhePhe: 1.039 ± 0.029	3.177PheGly: 3.177 ± 0.036	0.632PheHis: 0.632 ± 0.016	1.05PheIle: 1.05 ± 0.02	0.665PheLys: 0.665 ± 0.017	2.283PheLeu: 2.283 ± 0.034	0.642PheMet: 0.642 ± 0.014	0.768PheAsn: 0.768 ± 0.019	1.253PhePro: 1.253 ± 0.024	0.647PheGln: 0.647 ± 0.015	1.752PheArg: 1.752 ± 0.028	1.752PheSer: 1.752 ± 0.026	1.578PheThr: 1.578 ± 0.026	2.756PheVal: 2.756 ± 0.033	0.426PheTrp: 0.426 ± 0.014	0.707PheTyr: 0.707 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	9.386GlyAla: 9.386 ± 0.066	1.379GlyCys: 1.379 ± 0.029	7.845GlyAsp: 7.845 ± 0.149	6.655GlyGlu: 6.655 ± 0.061	2.956GlyPhe: 2.956 ± 0.039	7.818GlyGly: 7.818 ± 0.077	1.952GlyHis: 1.952 ± 0.026	2.997GlyIle: 2.997 ± 0.043	2.232GlyLys: 2.232 ± 0.037	9.24GlyLeu: 9.24 ± 0.083	1.774GlyMet: 1.774 ± 0.027	1.801GlyAsn: 1.801 ± 0.039	4.982GlyPro: 4.982 ± 0.049	2.969GlyGln: 2.969 ± 0.035	6.637GlyArg: 6.637 ± 0.065	5.007GlySer: 5.007 ± 0.045	4.143GlyThr: 4.143 ± 0.046	6.765GlyVal: 6.765 ± 0.06	1.383GlyTrp: 1.383 ± 0.023	1.912GlyTyr: 1.912 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	2.715HisAla: 2.715 ± 0.038	0.265HisCys: 0.265 ± 0.009	1.43HisAsp: 1.43 ± 0.023	1.698HisGlu: 1.698 ± 0.025	0.725HisPhe: 0.725 ± 0.017	2.086HisGly: 2.086 ± 0.032	0.602HisHis: 0.602 ± 0.016	0.662HisIle: 0.662 ± 0.019	0.424HisLys: 0.424 ± 0.014	2.086HisLeu: 2.086 ± 0.028	0.33HisMet: 0.33 ± 0.011	0.454HisAsn: 0.454 ± 0.013	1.461HisPro: 1.461 ± 0.023	0.622HisGln: 0.622 ± 0.016	1.743HisArg: 1.743 ± 0.032	0.978HisSer: 0.978 ± 0.018	0.891HisThr: 0.891 ± 0.017	1.606HisVal: 1.606 ± 0.025	0.332HisTrp: 0.332 ± 0.01	0.543HisTyr: 0.543 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.887IleAla: 4.887 ± 0.054	0.439IleCys: 0.439 ± 0.015	3.244IleAsp: 3.244 ± 0.037	3.587IleGlu: 3.587 ± 0.042	0.945IlePhe: 0.945 ± 0.02	3.48IleGly: 3.48 ± 0.037	0.922IleHis: 0.922 ± 0.019	1.258IleIle: 1.258 ± 0.025	0.9IleLys: 0.9 ± 0.021	2.994IleLeu: 2.994 ± 0.04	0.536IleMet: 0.536 ± 0.012	0.951IleAsn: 0.951 ± 0.018	2.031IlePro: 2.031 ± 0.031	1.013IleGln: 1.013 ± 0.022	2.515IleArg: 2.515 ± 0.031	2.068IleSer: 2.068 ± 0.029	1.801IleThr: 1.801 ± 0.028	3.191IleVal: 3.191 ± 0.041	0.48IleTrp: 0.48 ± 0.015	0.891IleTyr: 0.891 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	2.501LysAla: 2.501 ± 0.048	0.184LysCys: 0.184 ± 0.01	1.131LysAsp: 1.131 ± 0.027	0.847LysGlu: 0.847 ± 0.023	0.656LysPhe: 0.656 ± 0.017	1.59LysGly: 1.59 ± 0.034	0.506LysHis: 0.506 ± 0.013	1.277LysIle: 1.277 ± 0.027	1.102LysLys: 1.102 ± 0.063	3.051LysLeu: 3.051 ± 0.041	0.435LysMet: 0.435 ± 0.015	0.491LysAsn: 0.491 ± 0.016	1.586LysPro: 1.586 ± 0.03	0.884LysGln: 0.884 ± 0.022	1.918LysArg: 1.918 ± 0.032	1.157LysSer: 1.157 ± 0.028	1.275LysThr: 1.275 ± 0.026	1.859LysVal: 1.859 ± 0.03	0.284LysTrp: 0.284 ± 0.009	0.419LysTyr: 0.419 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	15.408LeuAla: 15.408 ± 0.138	1.187LeuCys: 1.187 ± 0.02	8.11LeuAsp: 8.11 ± 0.073	8.0LeuGlu: 8.0 ± 0.09	2.86LeuPhe: 2.86 ± 0.037	10.124LeuGly: 10.124 ± 0.092	2.113LeuHis: 2.113 ± 0.028	3.857LeuIle: 3.857 ± 0.038	1.499LeuLys: 1.499 ± 0.029	10.476LeuLeu: 10.476 ± 0.097	1.626LeuMet: 1.626 ± 0.026	1.669LeuAsn: 1.669 ± 0.027	5.473LeuPro: 5.473 ± 0.051	2.286LeuGln: 2.286 ± 0.034	9.06LeuArg: 9.06 ± 0.079	5.863LeuSer: 5.863 ± 0.052	4.873LeuThr: 4.873 ± 0.048	8.299LeuVal: 8.299 ± 0.069	1.445LeuTrp: 1.445 ± 0.03	1.775LeuTyr: 1.775 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.026MetAla: 2.026 ± 0.029	0.202MetCys: 0.202 ± 0.01	0.829MetAsp: 0.829 ± 0.018	0.695MetGlu: 0.695 ± 0.016	0.617MetPhe: 0.617 ± 0.016	1.312MetGly: 1.312 ± 0.022	0.376MetHis: 0.376 ± 0.011	0.894MetIle: 0.894 ± 0.018	0.478MetLys: 0.478 ± 0.014	1.975MetLeu: 1.975 ± 0.03	0.382MetMet: 0.382 ± 0.014	0.439MetAsn: 0.439 ± 0.014	1.143MetPro: 1.143 ± 0.022	0.543MetGln: 0.543 ± 0.016	1.506MetArg: 1.506 ± 0.026	1.401MetSer: 1.401 ± 0.023	1.24MetThr: 1.24 ± 0.022	1.263MetVal: 1.263 ± 0.026	0.212MetTrp: 0.212 ± 0.009	0.287MetTyr: 0.287 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.081AsnAla: 2.081 ± 0.032	0.306AsnCys: 0.306 ± 0.014	1.279AsnAsp: 1.279 ± 0.028	1.23AsnGlu: 1.23 ± 0.024	0.781AsnPhe: 0.781 ± 0.018	1.624AsnGly: 1.624 ± 0.03	0.514AsnHis: 0.514 ± 0.014	0.843AsnIle: 0.843 ± 0.021	0.57AsnLys: 0.57 ± 0.016	2.056AsnLeu: 2.056 ± 0.028	0.425AsnMet: 0.425 ± 0.015	0.663AsnAsn: 0.663 ± 0.017	1.527AsnPro: 1.527 ± 0.029	0.605AsnGln: 0.605 ± 0.014	1.181AsnArg: 1.181 ± 0.024	1.024AsnSer: 1.024 ± 0.023	1.056AsnThr: 1.056 ± 0.022	1.405AsnVal: 1.405 ± 0.027	0.307AsnTrp: 0.307 ± 0.011	0.558AsnTyr: 0.558 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	6.834ProAla: 6.834 ± 0.066	0.562ProCys: 0.562 ± 0.015	4.194ProAsp: 4.194 ± 0.041	5.289ProGlu: 5.289 ± 0.056	1.56ProPhe: 1.56 ± 0.027	5.776ProGly: 5.776 ± 0.057	0.979ProHis: 0.979 ± 0.021	2.111ProIle: 2.111 ± 0.027	1.555ProLys: 1.555 ± 0.029	5.0ProLeu: 5.0 ± 0.048	1.061ProMet: 1.061 ± 0.019	1.367ProAsn: 1.367 ± 0.026	3.791ProPro: 3.791 ± 0.053	1.495ProGln: 1.495 ± 0.03	4.234ProArg: 4.234 ± 0.042	3.869ProSer: 3.869 ± 0.045	2.992ProThr: 2.992 ± 0.037	3.82ProVal: 3.82 ± 0.042	0.913ProTrp: 0.913 ± 0.019	0.997ProTyr: 0.997 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.75GlnAla: 3.75 ± 0.049	0.305GlnCys: 0.305 ± 0.012	1.392GlnAsp: 1.392 ± 0.026	1.226GlnGlu: 1.226 ± 0.028	0.817GlnPhe: 0.817 ± 0.019	2.191GlnGly: 2.191 ± 0.03	0.613GlnHis: 0.613 ± 0.017	1.472GlnIle: 1.472 ± 0.023	0.577GlnLys: 0.577 ± 0.018	4.074GlnLeu: 4.074 ± 0.049	0.502GlnMet: 0.502 ± 0.014	0.531GlnAsn: 0.531 ± 0.013	1.892GlnPro: 1.892 ± 0.03	1.063GlnGln: 1.063 ± 0.029	2.82GlnArg: 2.82 ± 0.038	1.339GlnSer: 1.339 ± 0.027	1.571GlnThr: 1.571 ± 0.028	2.274GlnVal: 2.274 ± 0.03	0.446GlnTrp: 0.446 ± 0.015	0.506GlnTyr: 0.506 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	10.126ArgAla: 10.126 ± 0.099	0.885ArgCys: 0.885 ± 0.022	4.429ArgAsp: 4.429 ± 0.042	6.183ArgGlu: 6.183 ± 0.065	2.708ArgPhe: 2.708 ± 0.034	6.335ArgGly: 6.335 ± 0.076	1.672ArgHis: 1.672 ± 0.03	2.895ArgIle: 2.895 ± 0.033	1.962ArgLys: 1.962 ± 0.038	7.948ArgLeu: 7.948 ± 0.075	1.472ArgMet: 1.472 ± 0.022	1.29ArgAsn: 1.29 ± 0.022	4.09ArgPro: 4.09 ± 0.052	2.133ArgGln: 2.133 ± 0.027	7.355ArgArg: 7.355 ± 0.082	4.283ArgSer: 4.283 ± 0.05	3.132ArgThr: 3.132 ± 0.036	6.405ArgVal: 6.405 ± 0.065	1.524ArgTrp: 1.524 ± 0.028	1.807ArgTyr: 1.807 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	6.226SerAla: 6.226 ± 0.048	0.876SerCys: 0.876 ± 0.025	3.305SerAsp: 3.305 ± 0.043	3.708SerGlu: 3.708 ± 0.043	2.055SerPhe: 2.055 ± 0.025	5.385SerGly: 5.385 ± 0.058	0.994SerHis: 0.994 ± 0.021	2.0SerIle: 2.0 ± 0.029	1.296SerLys: 1.296 ± 0.023	5.676SerLeu: 5.676 ± 0.053	1.183SerMet: 1.183 ± 0.019	1.188SerAsn: 1.188 ± 0.022	3.312SerPro: 3.312 ± 0.037	1.396SerGln: 1.396 ± 0.022	3.567SerArg: 3.567 ± 0.04	3.672SerSer: 3.672 ± 0.048	2.893SerThr: 2.893 ± 0.037	3.902SerVal: 3.902 ± 0.042	0.94SerTrp: 0.94 ± 0.017	1.214SerTyr: 1.214 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	4.811ThrAla: 4.811 ± 0.051	0.721ThrCys: 0.721 ± 0.021	2.651ThrAsp: 2.651 ± 0.043	2.793ThrGlu: 2.793 ± 0.036	1.434ThrPhe: 1.434 ± 0.025	4.444ThrGly: 4.444 ± 0.05	1.045ThrHis: 1.045 ± 0.021	2.299ThrIle: 2.299 ± 0.032	1.394ThrLys: 1.394 ± 0.027	5.356ThrLeu: 5.356 ± 0.047	0.937ThrMet: 0.937 ± 0.019	1.147ThrAsn: 1.147 ± 0.025	3.161ThrPro: 3.161 ± 0.034	1.39ThrGln: 1.39 ± 0.026	3.465ThrArg: 3.465 ± 0.036	2.767ThrSer: 2.767 ± 0.04	2.811ThrThr: 2.811 ± 0.041	3.598ThrVal: 3.598 ± 0.044	0.813ThrTrp: 0.813 ± 0.02	1.053ThrTyr: 1.053 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	9.167ValAla: 9.167 ± 0.075	0.978ValCys: 0.978 ± 0.022	5.429ValAsp: 5.429 ± 0.046	6.375ValGlu: 6.375 ± 0.057	2.492ValPhe: 2.492 ± 0.038	6.433ValGly: 6.433 ± 0.058	1.777ValHis: 1.777 ± 0.027	3.012ValIle: 3.012 ± 0.036	1.407ValLys: 1.407 ± 0.028	7.495ValLeu: 7.495 ± 0.062	1.274ValMet: 1.274 ± 0.025	1.489ValAsn: 1.489 ± 0.025	3.667ValPro: 3.667 ± 0.035	1.797ValGln: 1.797 ± 0.029	5.344ValArg: 5.344 ± 0.052	4.02ValSer: 4.02 ± 0.047	3.532ValThr: 3.532 ± 0.047	6.627ValVal: 6.627 ± 0.076	1.046ValTrp: 1.046 ± 0.022	1.519ValTyr: 1.519 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.667TrpAla: 1.667 ± 0.027	0.187TrpCys: 0.187 ± 0.01	0.872TrpAsp: 0.872 ± 0.022	0.728TrpGlu: 0.728 ± 0.017	0.494TrpPhe: 0.494 ± 0.014	1.073TrpGly: 1.073 ± 0.023	0.3TrpHis: 0.3 ± 0.011	0.711TrpIle: 0.711 ± 0.017	0.307TrpLys: 0.307 ± 0.011	1.892TrpLeu: 1.892 ± 0.035	0.323TrpMet: 0.323 ± 0.012	0.336TrpAsn: 0.336 ± 0.011	0.776TrpPro: 0.776 ± 0.017	0.536TrpGln: 0.536 ± 0.014	1.254TrpArg: 1.254 ± 0.024	0.953TrpSer: 0.953 ± 0.02	0.915TrpThr: 0.915 ± 0.022	1.18TrpVal: 1.18 ± 0.023	0.27TrpTrp: 0.27 ± 0.011	0.296TrpTyr: 0.296 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.269TyrAla: 2.269 ± 0.031	0.31TyrCys: 0.31 ± 0.012	1.4TyrAsp: 1.4 ± 0.025	1.491TyrGlu: 1.491 ± 0.024	0.782TyrPhe: 0.782 ± 0.02	1.786TyrGly: 1.786 ± 0.027	0.449TyrHis: 0.449 ± 0.014	0.625TyrIle: 0.625 ± 0.018	0.429TyrLys: 0.429 ± 0.015	2.03TyrLeu: 2.03 ± 0.03	0.401TyrMet: 0.401 ± 0.013	0.429TyrAsn: 0.429 ± 0.013	0.993TyrPro: 0.993 ± 0.019	0.63TyrGln: 0.63 ± 0.017	1.598TyrArg: 1.598 ± 0.026	1.013TyrSer: 1.013 ± 0.021	0.974TyrThr: 0.974 ± 0.02	1.489TyrVal: 1.489 ± 0.026	0.34TyrTrp: 0.34 ± 0.011	0.561TyrTyr: 0.561 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6943 proteins (2649706 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---