Amino acid dipepetide frequency for Fowl aviadenovirus B

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.807AlaAla: 8.807 ± 1.501
1.215AlaCys: 1.215 ± 0.405
5.162AlaAsp: 5.162 ± 0.521
5.162AlaGlu: 5.162 ± 0.709
2.885AlaPhe: 2.885 ± 0.372
4.707AlaGly: 4.707 ± 0.696
1.594AlaHis: 1.594 ± 0.396
3.796AlaIle: 3.796 ± 0.53
1.974AlaLys: 1.974 ± 0.463
7.364AlaLeu: 7.364 ± 0.79
1.594AlaMet: 1.594 ± 0.474
3.113AlaAsn: 3.113 ± 0.46
4.859AlaPro: 4.859 ± 0.751
2.657AlaGln: 2.657 ± 0.548
4.1AlaArg: 4.1 ± 0.516
5.238AlaSer: 5.238 ± 0.64
4.251AlaThr: 4.251 ± 0.816
6.149AlaVal: 6.149 ± 0.639
0.759AlaTrp: 0.759 ± 0.243
3.416AlaTyr: 3.416 ± 0.538
0.0AlaXaa: 0.0 ± 0.0
Cys
1.063CysAla: 1.063 ± 0.211
0.228CysCys: 0.228 ± 0.137
1.063CysAsp: 1.063 ± 0.396
1.063CysGlu: 1.063 ± 0.283
0.607CysPhe: 0.607 ± 0.174
1.822CysGly: 1.822 ± 0.399
0.835CysHis: 0.835 ± 0.307
0.683CysIle: 0.683 ± 0.235
1.215CysLys: 1.215 ± 0.368
1.518CysLeu: 1.518 ± 0.387
0.759CysMet: 0.759 ± 0.215
0.911CysAsn: 0.911 ± 0.255
0.835CysPro: 0.835 ± 0.232
0.987CysGln: 0.987 ± 0.271
1.291CysArg: 1.291 ± 0.298
1.442CysSer: 1.442 ± 0.436
0.835CysThr: 0.835 ± 0.267
1.063CysVal: 1.063 ± 0.34
0.304CysTrp: 0.304 ± 0.136
0.759CysTyr: 0.759 ± 0.247
0.0CysXaa: 0.0 ± 0.0
Asp
4.631AspAla: 4.631 ± 0.913
0.835AspCys: 0.835 ± 0.203
3.113AspAsp: 3.113 ± 0.447
4.859AspGlu: 4.859 ± 0.659
1.974AspPhe: 1.974 ± 0.326
4.251AspGly: 4.251 ± 0.499
0.835AspHis: 0.835 ± 0.247
2.202AspIle: 2.202 ± 0.517
2.353AspLys: 2.353 ± 0.556
4.859AspLeu: 4.859 ± 0.5
1.063AspMet: 1.063 ± 0.337
1.594AspAsn: 1.594 ± 0.376
5.542AspPro: 5.542 ± 0.723
1.518AspGln: 1.518 ± 0.387
4.327AspArg: 4.327 ± 0.575
4.176AspSer: 4.176 ± 0.389
3.644AspThr: 3.644 ± 0.449
3.796AspVal: 3.796 ± 0.5
0.911AspTrp: 0.911 ± 0.249
2.05AspTyr: 2.05 ± 0.415
0.0AspXaa: 0.0 ± 0.0
Glu
3.492GluAla: 3.492 ± 0.465
0.683GluCys: 0.683 ± 0.235
4.555GluAsp: 4.555 ± 0.629
8.958GluGlu: 8.958 ± 1.708
1.594GluPhe: 1.594 ± 0.329
3.492GluGly: 3.492 ± 0.632
0.835GluHis: 0.835 ± 0.209
2.05GluIle: 2.05 ± 0.325
2.353GluLys: 2.353 ± 0.453
5.618GluLeu: 5.618 ± 0.535
1.215GluMet: 1.215 ± 0.339
3.189GluAsn: 3.189 ± 0.532
2.657GluPro: 2.657 ± 0.57
2.353GluGln: 2.353 ± 0.427
4.479GluArg: 4.479 ± 0.615
3.872GluSer: 3.872 ± 0.65
3.948GluThr: 3.948 ± 0.578
2.809GluVal: 2.809 ± 0.446
0.607GluTrp: 0.607 ± 0.164
1.898GluTyr: 1.898 ± 0.354
0.0GluXaa: 0.0 ± 0.0
Phe
2.961PheAla: 2.961 ± 0.433
0.683PheCys: 0.683 ± 0.264
2.733PheAsp: 2.733 ± 0.509
1.974PheGlu: 1.974 ± 0.274
1.518PhePhe: 1.518 ± 0.343
1.518PheGly: 1.518 ± 0.373
1.442PheHis: 1.442 ± 0.288
0.987PheIle: 0.987 ± 0.243
1.518PheLys: 1.518 ± 0.307
3.948PheLeu: 3.948 ± 0.526
1.215PheMet: 1.215 ± 0.35
1.974PheAsn: 1.974 ± 0.316
2.657PhePro: 2.657 ± 0.548
0.835PheGln: 0.835 ± 0.206
3.568PheArg: 3.568 ± 0.477
2.809PheSer: 2.809 ± 0.401
1.974PheThr: 1.974 ± 0.377
2.809PheVal: 2.809 ± 0.38
0.759PheTrp: 0.759 ± 0.224
2.126PheTyr: 2.126 ± 0.308
0.0PheXaa: 0.0 ± 0.0
Gly
6.529GlyAla: 6.529 ± 0.766
0.835GlyCys: 0.835 ± 0.262
3.416GlyAsp: 3.416 ± 0.482
4.024GlyGlu: 4.024 ± 0.617
2.05GlyPhe: 2.05 ± 0.325
7.06GlyGly: 7.06 ± 1.407
1.518GlyHis: 1.518 ± 0.496
2.429GlyIle: 2.429 ± 0.535
2.657GlyLys: 2.657 ± 0.584
4.555GlyLeu: 4.555 ± 0.667
1.67GlyMet: 1.67 ± 0.365
2.429GlyAsn: 2.429 ± 0.478
2.961GlyPro: 2.961 ± 0.559
1.67GlyGln: 1.67 ± 0.365
4.859GlyArg: 4.859 ± 0.68
4.479GlySer: 4.479 ± 0.523
4.327GlyThr: 4.327 ± 0.697
4.707GlyVal: 4.707 ± 0.69
1.215GlyTrp: 1.215 ± 0.19
2.278GlyTyr: 2.278 ± 0.336
0.0GlyXaa: 0.0 ± 0.0
His
1.746HisAla: 1.746 ± 0.319
0.987HisCys: 0.987 ± 0.366
1.139HisAsp: 1.139 ± 0.278
0.911HisGlu: 0.911 ± 0.232
0.987HisPhe: 0.987 ± 0.393
1.974HisGly: 1.974 ± 0.434
0.759HisHis: 0.759 ± 0.329
0.911HisIle: 0.911 ± 0.298
0.531HisLys: 0.531 ± 0.172
2.278HisLeu: 2.278 ± 0.436
0.38HisMet: 0.38 ± 0.164
0.911HisAsn: 0.911 ± 0.288
1.594HisPro: 1.594 ± 0.389
0.987HisGln: 0.987 ± 0.379
2.429HisArg: 2.429 ± 0.521
0.911HisSer: 0.911 ± 0.273
1.367HisThr: 1.367 ± 0.329
1.367HisVal: 1.367 ± 0.443
0.228HisTrp: 0.228 ± 0.123
1.063HisTyr: 1.063 ± 0.273
0.0HisXaa: 0.0 ± 0.0
Ile
3.34IleAla: 3.34 ± 0.472
1.139IleCys: 1.139 ± 0.334
2.809IleAsp: 2.809 ± 0.412
1.67IleGlu: 1.67 ± 0.273
1.291IlePhe: 1.291 ± 0.355
2.278IleGly: 2.278 ± 0.398
0.835IleHis: 0.835 ± 0.277
1.367IleIle: 1.367 ± 0.382
1.67IleLys: 1.67 ± 0.272
3.189IleLeu: 3.189 ± 0.445
0.456IleMet: 0.456 ± 0.153
1.594IleAsn: 1.594 ± 0.39
2.809IlePro: 2.809 ± 0.443
1.215IleGln: 1.215 ± 0.28
2.657IleArg: 2.657 ± 0.407
2.657IleSer: 2.657 ± 0.398
2.581IleThr: 2.581 ± 0.486
3.265IleVal: 3.265 ± 0.413
0.683IleTrp: 0.683 ± 0.176
1.67IleTyr: 1.67 ± 0.352
0.0IleXaa: 0.0 ± 0.0
Lys
2.733LysAla: 2.733 ± 0.469
0.987LysCys: 0.987 ± 0.303
2.202LysAsp: 2.202 ± 0.389
1.442LysGlu: 1.442 ± 0.427
1.67LysPhe: 1.67 ± 0.347
2.353LysGly: 2.353 ± 0.479
0.835LysHis: 0.835 ± 0.294
1.291LysIle: 1.291 ± 0.279
2.202LysLys: 2.202 ± 0.754
3.34LysLeu: 3.34 ± 0.576
1.139LysMet: 1.139 ± 0.309
1.822LysAsn: 1.822 ± 0.349
1.898LysPro: 1.898 ± 0.389
1.139LysGln: 1.139 ± 0.326
3.796LysArg: 3.796 ± 0.735
1.518LysSer: 1.518 ± 0.337
2.202LysThr: 2.202 ± 0.331
1.67LysVal: 1.67 ± 0.258
0.531LysTrp: 0.531 ± 0.186
1.442LysTyr: 1.442 ± 0.424
0.0LysXaa: 0.0 ± 0.0
Leu
5.922LeuAla: 5.922 ± 0.679
1.518LeuCys: 1.518 ± 0.332
4.935LeuAsp: 4.935 ± 0.589
4.555LeuGlu: 4.555 ± 0.739
4.479LeuPhe: 4.479 ± 0.435
4.631LeuGly: 4.631 ± 0.66
2.202LeuHis: 2.202 ± 0.553
3.644LeuIle: 3.644 ± 0.454
3.644LeuLys: 3.644 ± 0.55
7.971LeuLeu: 7.971 ± 0.828
2.581LeuMet: 2.581 ± 0.399
3.265LeuAsn: 3.265 ± 0.479
5.162LeuPro: 5.162 ± 0.613
4.176LeuGln: 4.176 ± 0.513
7.288LeuArg: 7.288 ± 1.088
6.225LeuSer: 6.225 ± 0.687
5.998LeuThr: 5.998 ± 0.692
4.631LeuVal: 4.631 ± 0.628
1.518LeuTrp: 1.518 ± 0.308
3.34LeuTyr: 3.34 ± 0.477
0.0LeuXaa: 0.0 ± 0.0
Met
2.278MetAla: 2.278 ± 0.463
0.228MetCys: 0.228 ± 0.13
1.442MetAsp: 1.442 ± 0.296
1.291MetGlu: 1.291 ± 0.423
0.835MetPhe: 0.835 ± 0.216
1.063MetGly: 1.063 ± 0.312
0.531MetHis: 0.531 ± 0.203
0.835MetIle: 0.835 ± 0.252
0.759MetLys: 0.759 ± 0.183
1.898MetLeu: 1.898 ± 0.325
0.456MetMet: 0.456 ± 0.253
0.835MetAsn: 0.835 ± 0.198
2.05MetPro: 2.05 ± 0.319
0.759MetGln: 0.759 ± 0.227
1.898MetArg: 1.898 ± 0.288
1.822MetSer: 1.822 ± 0.463
1.291MetThr: 1.291 ± 0.414
1.518MetVal: 1.518 ± 0.344
0.304MetTrp: 0.304 ± 0.116
0.987MetTyr: 0.987 ± 0.257
0.0MetXaa: 0.0 ± 0.0
Asn
2.353AsnAla: 2.353 ± 0.41
0.607AsnCys: 0.607 ± 0.214
2.429AsnAsp: 2.429 ± 0.546
2.126AsnGlu: 2.126 ± 0.497
1.518AsnPhe: 1.518 ± 0.555
1.898AsnGly: 1.898 ± 0.296
0.987AsnHis: 0.987 ± 0.256
1.974AsnIle: 1.974 ± 0.591
0.911AsnLys: 0.911 ± 0.267
3.72AsnLeu: 3.72 ± 0.516
1.139AsnMet: 1.139 ± 0.339
1.594AsnAsn: 1.594 ± 0.453
3.948AsnPro: 3.948 ± 0.552
1.518AsnGln: 1.518 ± 0.416
2.809AsnArg: 2.809 ± 0.549
3.113AsnSer: 3.113 ± 0.647
1.974AsnThr: 1.974 ± 0.335
3.416AsnVal: 3.416 ± 0.521
0.456AsnTrp: 0.456 ± 0.262
2.126AsnTyr: 2.126 ± 0.494
0.0AsnXaa: 0.0 ± 0.0
Pro
5.314ProAla: 5.314 ± 0.747
1.442ProCys: 1.442 ± 0.323
3.796ProAsp: 3.796 ± 0.465
4.024ProGlu: 4.024 ± 0.566
3.416ProPhe: 3.416 ± 0.585
2.961ProGly: 2.961 ± 0.354
1.746ProHis: 1.746 ± 0.32
2.353ProIle: 2.353 ± 0.488
1.594ProLys: 1.594 ± 0.321
5.087ProLeu: 5.087 ± 1.005
1.594ProMet: 1.594 ± 0.329
2.278ProAsn: 2.278 ± 0.53
6.073ProPro: 6.073 ± 0.954
2.353ProGln: 2.353 ± 0.471
4.1ProArg: 4.1 ± 0.585
5.846ProSer: 5.846 ± 0.765
4.631ProThr: 4.631 ± 0.574
4.327ProVal: 4.327 ± 0.748
0.607ProTrp: 0.607 ± 0.219
2.505ProTyr: 2.505 ± 0.397
0.0ProXaa: 0.0 ± 0.0
Gln
3.037GlnAla: 3.037 ± 0.501
0.38GlnCys: 0.38 ± 0.171
1.367GlnAsp: 1.367 ± 0.309
1.67GlnGlu: 1.67 ± 0.295
1.442GlnPhe: 1.442 ± 0.294
1.518GlnGly: 1.518 ± 0.379
1.215GlnHis: 1.215 ± 0.458
1.442GlnIle: 1.442 ± 0.266
1.822GlnLys: 1.822 ± 0.309
4.327GlnLeu: 4.327 ± 0.4
0.911GlnMet: 0.911 ± 0.31
1.746GlnAsn: 1.746 ± 0.385
1.822GlnPro: 1.822 ± 0.403
2.05GlnGln: 2.05 ± 0.492
1.974GlnArg: 1.974 ± 0.457
2.278GlnSer: 2.278 ± 0.381
3.113GlnThr: 3.113 ± 0.531
1.822GlnVal: 1.822 ± 0.334
0.607GlnTrp: 0.607 ± 0.188
1.215GlnTyr: 1.215 ± 0.309
0.0GlnXaa: 0.0 ± 0.0
Arg
5.314ArgAla: 5.314 ± 0.799
1.215ArgCys: 1.215 ± 0.274
3.568ArgAsp: 3.568 ± 0.682
4.176ArgGlu: 4.176 ± 0.584
3.113ArgPhe: 3.113 ± 0.437
4.555ArgGly: 4.555 ± 0.803
2.581ArgHis: 2.581 ± 0.404
3.037ArgIle: 3.037 ± 0.547
2.809ArgLys: 2.809 ± 0.466
6.453ArgLeu: 6.453 ± 0.808
1.67ArgMet: 1.67 ± 0.263
3.037ArgAsn: 3.037 ± 0.825
4.327ArgPro: 4.327 ± 0.785
2.733ArgGln: 2.733 ± 0.452
8.503ArgArg: 8.503 ± 1.56
5.694ArgSer: 5.694 ± 0.71
3.568ArgThr: 3.568 ± 0.462
5.011ArgVal: 5.011 ± 0.581
1.442ArgTrp: 1.442 ± 0.302
2.961ArgTyr: 2.961 ± 0.509
0.0ArgXaa: 0.0 ± 0.0
Ser
5.694SerAla: 5.694 ± 0.541
1.67SerCys: 1.67 ± 0.378
4.935SerAsp: 4.935 ± 0.772
4.783SerGlu: 4.783 ± 0.571
2.885SerPhe: 2.885 ± 0.494
6.909SerGly: 6.909 ± 0.873
1.215SerHis: 1.215 ± 0.302
2.657SerIle: 2.657 ± 0.44
2.202SerLys: 2.202 ± 0.672
5.618SerLeu: 5.618 ± 0.731
1.518SerMet: 1.518 ± 0.425
2.505SerAsn: 2.505 ± 0.432
4.555SerPro: 4.555 ± 0.708
1.822SerGln: 1.822 ± 0.382
5.466SerArg: 5.466 ± 0.821
6.833SerSer: 6.833 ± 1.121
2.809SerThr: 2.809 ± 0.502
3.72SerVal: 3.72 ± 0.517
0.911SerTrp: 0.911 ± 0.286
2.278SerTyr: 2.278 ± 0.368
0.0SerXaa: 0.0 ± 0.0
Thr
5.846ThrAla: 5.846 ± 0.766
1.367ThrCys: 1.367 ± 0.39
2.809ThrAsp: 2.809 ± 0.422
3.113ThrGlu: 3.113 ± 0.475
2.126ThrPhe: 2.126 ± 0.334
3.796ThrGly: 3.796 ± 0.679
1.291ThrHis: 1.291 ± 0.282
2.202ThrIle: 2.202 ± 0.409
1.67ThrLys: 1.67 ± 0.342
5.846ThrLeu: 5.846 ± 0.738
1.291ThrMet: 1.291 ± 0.3
2.429ThrAsn: 2.429 ± 0.706
4.176ThrPro: 4.176 ± 0.684
2.05ThrGln: 2.05 ± 0.417
3.34ThrArg: 3.34 ± 0.492
4.555ThrSer: 4.555 ± 0.574
4.176ThrThr: 4.176 ± 1.102
4.251ThrVal: 4.251 ± 0.525
0.607ThrTrp: 0.607 ± 0.186
2.885ThrTyr: 2.885 ± 0.575
0.0ThrXaa: 0.0 ± 0.0
Val
4.327ValAla: 4.327 ± 0.529
1.594ValCys: 1.594 ± 0.325
3.113ValAsp: 3.113 ± 0.376
2.581ValGlu: 2.581 ± 0.431
2.581ValPhe: 2.581 ± 0.444
4.707ValGly: 4.707 ± 0.625
1.063ValHis: 1.063 ± 0.253
3.34ValIle: 3.34 ± 0.662
1.898ValLys: 1.898 ± 0.346
5.314ValLeu: 5.314 ± 0.551
1.291ValMet: 1.291 ± 0.236
2.961ValAsn: 2.961 ± 0.532
5.39ValPro: 5.39 ± 0.682
2.733ValGln: 2.733 ± 0.711
4.935ValArg: 4.935 ± 0.574
4.024ValSer: 4.024 ± 0.596
4.707ValThr: 4.707 ± 0.497
3.72ValVal: 3.72 ± 0.584
0.759ValTrp: 0.759 ± 0.226
2.961ValTyr: 2.961 ± 0.318
0.0ValXaa: 0.0 ± 0.0
Trp
0.835TrpAla: 0.835 ± 0.279
0.531TrpCys: 0.531 ± 0.22
0.987TrpAsp: 0.987 ± 0.329
0.683TrpGlu: 0.683 ± 0.206
0.456TrpPhe: 0.456 ± 0.186
0.987TrpGly: 0.987 ± 0.221
0.304TrpHis: 0.304 ± 0.151
0.835TrpIle: 0.835 ± 0.269
0.835TrpLys: 0.835 ± 0.253
1.291TrpLeu: 1.291 ± 0.309
0.152TrpMet: 0.152 ± 0.132
0.759TrpAsn: 0.759 ± 0.21
0.456TrpPro: 0.456 ± 0.401
0.759TrpGln: 0.759 ± 0.237
1.291TrpArg: 1.291 ± 0.302
0.683TrpSer: 0.683 ± 0.205
0.835TrpThr: 0.835 ± 0.222
0.835TrpVal: 0.835 ± 0.266
0.228TrpTrp: 0.228 ± 0.115
0.683TrpTyr: 0.683 ± 0.207
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.581TyrAla: 2.581 ± 0.412
1.139TyrCys: 1.139 ± 0.236
2.961TyrAsp: 2.961 ± 0.442
1.594TyrGlu: 1.594 ± 0.331
2.581TyrPhe: 2.581 ± 0.43
3.189TyrGly: 3.189 ± 0.414
0.835TyrHis: 0.835 ± 0.23
1.139TyrIle: 1.139 ± 0.297
1.594TyrLys: 1.594 ± 0.425
3.492TyrLeu: 3.492 ± 0.65
0.911TyrMet: 0.911 ± 0.409
1.67TyrAsn: 1.67 ± 0.402
2.278TyrPro: 2.278 ± 0.414
1.442TyrGln: 1.442 ± 0.193
2.657TyrArg: 2.657 ± 0.415
2.809TyrSer: 2.809 ± 0.523
1.594TyrThr: 1.594 ± 0.258
3.113TyrVal: 3.113 ± 0.437
1.063TyrTrp: 1.063 ± 0.285
1.367TyrTyr: 1.367 ± 0.48
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 36 proteins (13173 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski