Amino acid dipepetide frequency for Budgerigar fledgling disease virus - 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.419AlaAla: 8.419 ± 2.465
0.468AlaCys: 0.468 ± 0.452
3.274AlaAsp: 3.274 ± 1.216
3.742AlaGlu: 3.742 ± 1.348
4.21AlaPhe: 4.21 ± 1.766
5.145AlaGly: 5.145 ± 2.182
2.806AlaHis: 2.806 ± 0.959
3.742AlaIle: 3.742 ± 1.693
1.403AlaLys: 1.403 ± 0.637
10.29AlaLeu: 10.29 ± 2.292
1.403AlaMet: 1.403 ± 0.53
1.403AlaAsn: 1.403 ± 0.841
5.145AlaPro: 5.145 ± 2.496
4.21AlaGln: 4.21 ± 1.427
6.548AlaArg: 6.548 ± 1.204
4.677AlaSer: 4.677 ± 1.208
5.613AlaThr: 5.613 ± 2.149
7.484AlaVal: 7.484 ± 2.576
0.935AlaTrp: 0.935 ± 0.55
2.339AlaTyr: 2.339 ± 0.878
0.0AlaXaa: 0.0 ± 0.0
Cys
2.339CysAla: 2.339 ± 0.849
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.468CysGly: 0.468 ± 0.452
0.468CysHis: 0.468 ± 0.331
0.0CysIle: 0.0 ± 0.0
0.935CysLys: 0.935 ± 0.447
0.935CysLeu: 0.935 ± 0.561
0.935CysMet: 0.935 ± 0.699
0.0CysAsn: 0.0 ± 0.0
2.339CysPro: 2.339 ± 1.261
0.935CysGln: 0.935 ± 0.661
0.0CysArg: 0.0 ± 0.0
0.935CysSer: 0.935 ± 0.661
1.403CysThr: 1.403 ± 0.992
0.935CysVal: 0.935 ± 0.661
0.468CysTrp: 0.468 ± 0.452
0.468CysTyr: 0.468 ± 0.452
0.0CysXaa: 0.0 ± 0.0
Asp
3.274AspAla: 3.274 ± 1.023
0.935AspCys: 0.935 ± 0.661
2.339AspAsp: 2.339 ± 0.862
3.742AspGlu: 3.742 ± 1.546
1.403AspPhe: 1.403 ± 0.584
2.806AspGly: 2.806 ± 1.007
0.935AspHis: 0.935 ± 0.661
6.08AspIle: 6.08 ± 1.722
2.339AspLys: 2.339 ± 0.878
4.21AspLeu: 4.21 ± 0.673
0.935AspMet: 0.935 ± 0.447
0.935AspAsn: 0.935 ± 0.661
4.677AspPro: 4.677 ± 1.997
2.339AspGln: 2.339 ± 0.537
0.935AspArg: 0.935 ± 0.487
2.806AspSer: 2.806 ± 0.465
2.339AspThr: 2.339 ± 0.537
4.677AspVal: 4.677 ± 0.758
0.935AspTrp: 0.935 ± 0.55
0.935AspTyr: 0.935 ± 0.661
0.0AspXaa: 0.0 ± 0.0
Glu
4.677GluAla: 4.677 ± 1.34
1.403GluCys: 1.403 ± 0.643
3.742GluAsp: 3.742 ± 1.152
4.677GluGlu: 4.677 ± 1.458
1.403GluPhe: 1.403 ± 0.723
5.613GluGly: 5.613 ± 1.245
0.468GluHis: 0.468 ± 0.331
2.339GluIle: 2.339 ± 0.786
2.806GluLys: 2.806 ± 1.568
7.484GluLeu: 7.484 ± 1.954
1.403GluMet: 1.403 ± 0.614
2.339GluAsn: 2.339 ± 0.895
3.274GluPro: 3.274 ± 0.876
2.339GluGln: 2.339 ± 1.028
5.613GluArg: 5.613 ± 0.967
3.742GluSer: 3.742 ± 1.721
7.484GluThr: 7.484 ± 1.708
3.742GluVal: 3.742 ± 1.473
1.871GluTrp: 1.871 ± 1.1
0.468GluTyr: 0.468 ± 0.571
0.0GluXaa: 0.0 ± 0.0
Phe
0.468PheAla: 0.468 ± 0.412
0.468PheCys: 0.468 ± 0.331
0.468PheAsp: 0.468 ± 0.412
4.21PheGlu: 4.21 ± 1.251
2.806PhePhe: 2.806 ± 0.975
1.403PheGly: 1.403 ± 0.695
0.0PheHis: 0.0 ± 0.0
0.468PheIle: 0.468 ± 0.412
1.871PheLys: 1.871 ± 1.123
1.403PheLeu: 1.403 ± 0.643
1.403PheMet: 1.403 ± 0.708
2.339PheAsn: 2.339 ± 0.906
1.871PhePro: 1.871 ± 0.691
1.871PheGln: 1.871 ± 0.94
3.742PheArg: 3.742 ± 0.783
4.21PheSer: 4.21 ± 1.347
2.339PheThr: 2.339 ± 1.184
0.468PheVal: 0.468 ± 0.331
0.0PheTrp: 0.0 ± 0.0
0.935PheTyr: 0.935 ± 0.688
0.0PheXaa: 0.0 ± 0.0
Gly
4.677GlyAla: 4.677 ± 1.401
0.468GlyCys: 0.468 ± 0.331
2.806GlyAsp: 2.806 ± 0.682
4.21GlyGlu: 4.21 ± 1.181
0.935GlyPhe: 0.935 ± 0.447
4.677GlyGly: 4.677 ± 1.973
0.935GlyHis: 0.935 ± 0.487
3.742GlyIle: 3.742 ± 1.046
2.339GlyLys: 2.339 ± 0.478
7.484GlyLeu: 7.484 ± 1.818
0.935GlyMet: 0.935 ± 0.447
2.339GlyAsn: 2.339 ± 0.876
6.548GlyPro: 6.548 ± 2.477
4.21GlyGln: 4.21 ± 1.824
3.742GlyArg: 3.742 ± 1.573
3.274GlySer: 3.274 ± 1.375
5.613GlyThr: 5.613 ± 0.946
1.871GlyVal: 1.871 ± 0.888
0.0GlyTrp: 0.0 ± 0.0
2.806GlyTyr: 2.806 ± 1.72
0.0GlyXaa: 0.0 ± 0.0
His
1.871HisAla: 1.871 ± 0.691
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.806HisGlu: 2.806 ± 0.774
0.935HisPhe: 0.935 ± 0.447
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.403HisIle: 1.403 ± 0.992
0.0HisLys: 0.0 ± 0.0
3.742HisLeu: 3.742 ± 1.576
0.468HisMet: 0.468 ± 0.331
1.871HisAsn: 1.871 ± 0.691
1.403HisPro: 1.403 ± 0.723
2.806HisGln: 2.806 ± 0.882
0.468HisArg: 0.468 ± 0.459
1.871HisSer: 1.871 ± 1.044
0.468HisThr: 0.468 ± 0.331
0.0HisVal: 0.0 ± 0.0
0.468HisTrp: 0.468 ± 0.331
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.403IleAla: 1.403 ± 0.776
0.935IleCys: 0.935 ± 0.447
3.274IleAsp: 3.274 ± 1.433
5.613IleGlu: 5.613 ± 2.015
2.339IlePhe: 2.339 ± 0.844
2.806IleGly: 2.806 ± 1.186
1.403IleHis: 1.403 ± 0.584
0.935IleIle: 0.935 ± 0.431
3.274IleLys: 3.274 ± 1.882
5.145IleLeu: 5.145 ± 1.291
0.0IleMet: 0.0 ± 0.0
1.403IleAsn: 1.403 ± 0.584
0.935IlePro: 0.935 ± 0.571
3.274IleGln: 3.274 ± 0.557
2.339IleArg: 2.339 ± 1.02
2.339IleSer: 2.339 ± 1.244
4.21IleThr: 4.21 ± 1.477
1.403IleVal: 1.403 ± 0.53
0.935IleTrp: 0.935 ± 0.55
1.403IleTyr: 1.403 ± 0.53
0.0IleXaa: 0.0 ± 0.0
Lys
3.742LysAla: 3.742 ± 0.682
0.935LysCys: 0.935 ± 0.561
1.871LysAsp: 1.871 ± 0.92
3.274LysGlu: 3.274 ± 0.884
0.468LysPhe: 0.468 ± 0.331
4.21LysGly: 4.21 ± 1.695
1.403LysHis: 1.403 ± 0.695
0.0LysIle: 0.0 ± 0.0
2.339LysLys: 2.339 ± 0.668
2.339LysLeu: 2.339 ± 1.332
1.871LysMet: 1.871 ± 0.816
1.871LysAsn: 1.871 ± 0.893
0.935LysPro: 0.935 ± 0.661
0.935LysGln: 0.935 ± 0.561
7.484LysArg: 7.484 ± 2.295
1.871LysSer: 1.871 ± 0.669
2.806LysThr: 2.806 ± 1.001
2.339LysVal: 2.339 ± 0.668
0.0LysTrp: 0.0 ± 0.0
1.403LysTyr: 1.403 ± 0.723
0.0LysXaa: 0.0 ± 0.0
Leu
9.355LeuAla: 9.355 ± 2.314
2.806LeuCys: 2.806 ± 1.142
5.145LeuAsp: 5.145 ± 2.096
7.484LeuGlu: 7.484 ± 1.715
5.613LeuPhe: 5.613 ± 0.769
3.274LeuGly: 3.274 ± 1.214
2.806LeuHis: 2.806 ± 1.535
6.08LeuIle: 6.08 ± 1.372
5.613LeuLys: 5.613 ± 1.509
16.37LeuLeu: 16.37 ± 6.861
2.339LeuMet: 2.339 ± 1.263
4.21LeuAsn: 4.21 ± 0.802
7.484LeuPro: 7.484 ± 1.714
4.677LeuGln: 4.677 ± 0.919
7.951LeuArg: 7.951 ± 2.308
2.806LeuSer: 2.806 ± 1.404
6.08LeuThr: 6.08 ± 1.717
1.871LeuVal: 1.871 ± 0.591
0.0LeuTrp: 0.0 ± 0.0
3.274LeuTyr: 3.274 ± 0.877
0.0LeuXaa: 0.0 ± 0.0
Met
1.871MetAla: 1.871 ± 0.607
0.0MetCys: 0.0 ± 0.0
0.935MetAsp: 0.935 ± 0.55
1.403MetGlu: 1.403 ± 0.603
0.468MetPhe: 0.468 ± 0.571
0.468MetGly: 0.468 ± 0.412
0.935MetHis: 0.935 ± 0.447
0.0MetIle: 0.0 ± 0.0
1.403MetLys: 1.403 ± 1.082
1.403MetLeu: 1.403 ± 0.992
0.0MetMet: 0.0 ± 0.0
0.935MetAsn: 0.935 ± 0.661
2.339MetPro: 2.339 ± 1.018
2.339MetGln: 2.339 ± 0.956
0.0MetArg: 0.0 ± 0.0
1.403MetSer: 1.403 ± 0.759
3.274MetThr: 3.274 ± 0.948
1.403MetVal: 1.403 ± 0.992
0.468MetTrp: 0.468 ± 0.452
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.339AsnAla: 2.339 ± 0.743
0.468AsnCys: 0.468 ± 0.331
1.871AsnAsp: 1.871 ± 0.888
0.935AsnGlu: 0.935 ± 0.699
1.871AsnPhe: 1.871 ± 0.782
3.274AsnGly: 3.274 ± 1.326
0.935AsnHis: 0.935 ± 0.688
2.806AsnIle: 2.806 ± 1.059
0.468AsnLys: 0.468 ± 0.331
2.806AsnLeu: 2.806 ± 1.539
1.871AsnMet: 1.871 ± 0.604
1.871AsnAsn: 1.871 ± 0.935
2.339AsnPro: 2.339 ± 0.537
0.0AsnGln: 0.0 ± 0.0
2.806AsnArg: 2.806 ± 1.798
1.871AsnSer: 1.871 ± 1.044
4.21AsnThr: 4.21 ± 0.902
2.806AsnVal: 2.806 ± 0.465
0.0AsnTrp: 0.0 ± 0.0
1.403AsnTyr: 1.403 ± 0.53
0.0AsnXaa: 0.0 ± 0.0
Pro
6.08ProAla: 6.08 ± 2.79
0.468ProCys: 0.468 ± 0.452
5.145ProAsp: 5.145 ± 1.421
8.419ProGlu: 8.419 ± 1.779
1.871ProPhe: 1.871 ± 1.375
6.548ProGly: 6.548 ± 1.807
0.935ProHis: 0.935 ± 0.447
0.468ProIle: 0.468 ± 0.452
2.339ProLys: 2.339 ± 0.537
6.08ProLeu: 6.08 ± 2.49
0.468ProMet: 0.468 ± 0.482
4.677ProAsn: 4.677 ± 2.783
6.08ProPro: 6.08 ± 1.036
2.806ProGln: 2.806 ± 0.768
4.677ProArg: 4.677 ± 2.954
5.613ProSer: 5.613 ± 2.001
8.419ProThr: 8.419 ± 3.063
3.742ProVal: 3.742 ± 0.91
0.468ProTrp: 0.468 ± 0.571
0.935ProTyr: 0.935 ± 0.591
0.0ProXaa: 0.0 ± 0.0
Gln
3.274GlnAla: 3.274 ± 0.831
0.468GlnCys: 0.468 ± 0.331
3.742GlnAsp: 3.742 ± 0.929
1.871GlnGlu: 1.871 ± 0.608
1.403GlnPhe: 1.403 ± 0.992
2.806GlnGly: 2.806 ± 0.89
0.468GlnHis: 0.468 ± 0.331
1.871GlnIle: 1.871 ± 0.691
2.806GlnLys: 2.806 ± 0.713
2.806GlnLeu: 2.806 ± 0.478
0.935GlnMet: 0.935 ± 0.55
1.403GlnAsn: 1.403 ± 0.512
4.677GlnPro: 4.677 ± 2.141
1.871GlnGln: 1.871 ± 0.835
1.871GlnArg: 1.871 ± 0.453
3.742GlnSer: 3.742 ± 1.426
5.613GlnThr: 5.613 ± 1.701
3.274GlnVal: 3.274 ± 1.434
0.0GlnTrp: 0.0 ± 0.0
1.403GlnTyr: 1.403 ± 0.643
0.0GlnXaa: 0.0 ± 0.0
Arg
4.21ArgAla: 4.21 ± 0.583
0.0ArgCys: 0.0 ± 0.0
3.274ArgAsp: 3.274 ± 0.839
1.871ArgGlu: 1.871 ± 0.737
1.871ArgPhe: 1.871 ± 0.973
4.21ArgGly: 4.21 ± 0.923
1.403ArgHis: 1.403 ± 0.53
3.274ArgIle: 3.274 ± 0.895
4.677ArgLys: 4.677 ± 1.243
10.29ArgLeu: 10.29 ± 4.061
2.806ArgMet: 2.806 ± 0.956
1.871ArgAsn: 1.871 ± 0.893
4.677ArgPro: 4.677 ± 1.674
1.871ArgGln: 1.871 ± 1.102
7.016ArgArg: 7.016 ± 1.802
4.21ArgSer: 4.21 ± 1.236
4.21ArgThr: 4.21 ± 1.316
1.403ArgVal: 1.403 ± 0.584
0.935ArgTrp: 0.935 ± 0.55
4.21ArgTyr: 4.21 ± 1.427
0.0ArgXaa: 0.0 ± 0.0
Ser
3.274SerAla: 3.274 ± 0.984
2.339SerCys: 2.339 ± 1.018
3.274SerAsp: 3.274 ± 0.703
2.339SerGlu: 2.339 ± 1.172
0.935SerPhe: 0.935 ± 0.55
5.145SerGly: 5.145 ± 1.169
0.0SerHis: 0.0 ± 0.0
4.677SerIle: 4.677 ± 1.094
1.403SerLys: 1.403 ± 0.584
6.08SerLeu: 6.08 ± 1.07
0.468SerMet: 0.468 ± 0.452
0.935SerAsn: 0.935 ± 0.55
5.145SerPro: 5.145 ± 2.857
3.274SerGln: 3.274 ± 1.308
3.274SerArg: 3.274 ± 1.402
0.468SerSer: 0.468 ± 0.452
7.016SerThr: 7.016 ± 2.405
6.08SerVal: 6.08 ± 1.227
0.0SerTrp: 0.0 ± 0.0
0.935SerTyr: 0.935 ± 0.55
0.0SerXaa: 0.0 ± 0.0
Thr
14.5ThrAla: 14.5 ± 3.299
0.468ThrCys: 0.468 ± 0.452
1.403ThrAsp: 1.403 ± 0.992
6.548ThrGlu: 6.548 ± 2.03
1.871ThrPhe: 1.871 ± 0.842
5.613ThrGly: 5.613 ± 0.92
0.468ThrHis: 0.468 ± 0.331
3.742ThrIle: 3.742 ± 1.473
1.403ThrLys: 1.403 ± 0.695
7.951ThrLeu: 7.951 ± 1.552
1.403ThrMet: 1.403 ± 0.992
1.871ThrAsn: 1.871 ± 0.651
9.822ThrPro: 9.822 ± 2.955
1.871ThrGln: 1.871 ± 1.242
1.871ThrArg: 1.871 ± 0.702
6.548ThrSer: 6.548 ± 2.079
8.887ThrThr: 8.887 ± 1.918
4.677ThrVal: 4.677 ± 1.622
0.0ThrTrp: 0.0 ± 0.0
1.871ThrTyr: 1.871 ± 0.713
0.0ThrXaa: 0.0 ± 0.0
Val
4.21ValAla: 4.21 ± 1.454
0.0ValCys: 0.0 ± 0.0
5.145ValAsp: 5.145 ± 1.481
1.403ValGlu: 1.403 ± 0.584
0.0ValPhe: 0.0 ± 0.0
2.339ValGly: 2.339 ± 1.282
2.339ValHis: 2.339 ± 0.945
2.339ValIle: 2.339 ± 0.537
3.274ValLys: 3.274 ± 1.242
6.08ValLeu: 6.08 ± 1.327
0.0ValMet: 0.0 ± 0.0
3.274ValAsn: 3.274 ± 1.454
5.145ValPro: 5.145 ± 1.037
1.403ValGln: 1.403 ± 0.643
3.742ValArg: 3.742 ± 1.015
3.274ValSer: 3.274 ± 1.116
1.403ValThr: 1.403 ± 0.723
0.935ValVal: 0.935 ± 0.447
0.935ValTrp: 0.935 ± 0.55
2.806ValTyr: 2.806 ± 0.704
0.0ValXaa: 0.0 ± 0.0
Trp
0.935TrpAla: 0.935 ± 0.55
0.468TrpCys: 0.468 ± 0.452
0.0TrpAsp: 0.0 ± 0.0
0.468TrpGlu: 0.468 ± 0.452
0.935TrpPhe: 0.935 ± 0.55
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.468TrpLys: 0.468 ± 0.571
0.935TrpLeu: 0.935 ± 0.55
0.0TrpMet: 0.0 ± 0.0
0.935TrpAsn: 0.935 ± 0.55
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.339TrpArg: 2.339 ± 1.041
0.0TrpSer: 0.0 ± 0.0
1.403TrpThr: 1.403 ± 0.53
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.339TyrAla: 2.339 ± 1.015
0.468TyrCys: 0.468 ± 0.331
1.871TyrAsp: 1.871 ± 0.608
2.339TyrGlu: 2.339 ± 0.537
1.403TyrPhe: 1.403 ± 1.193
2.806TyrGly: 2.806 ± 1.169
1.871TyrHis: 1.871 ± 0.607
1.403TyrIle: 1.403 ± 0.658
0.935TyrLys: 0.935 ± 0.447
1.403TyrLeu: 1.403 ± 0.643
0.935TyrMet: 0.935 ± 0.55
0.468TyrAsn: 0.468 ± 0.331
1.403TyrPro: 1.403 ± 1.355
3.274TyrGln: 3.274 ± 1.559
1.871TyrArg: 1.871 ± 0.607
1.403TyrSer: 1.403 ± 0.835
0.0TyrThr: 0.0 ± 0.0
0.935TyrVal: 0.935 ± 0.447
0.468TyrTrp: 0.468 ± 0.452
1.871TyrTyr: 1.871 ± 0.453
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (2139 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski